Cancer - Cancer Science

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If the spread is not controlled, it can result in death. Cancer can develop in almost any tissue or organ in the body and is often named after the part of the body where it starts.</div><div><a href="https://cancerscience.net/knowledgebase/how-does-cancer-develop" title="How Does Cancer Develop?"><h3>How Does Cancer Develop?</h3></a>Cancer develops when cells acquire mutations in their <a href="https://cancerscience.net/about/index/dna" title="DNA" target="_blank">DNA</a> that enable them to grow and divide uncontrollably. These mutations can be caused by various factors, including exposure to <a href="https://cancerscience.net/about/index/carcinogens" title="carcinogens" target="_blank">carcinogens</a> such as tobacco smoke, radiation, and certain chemicals. Genetic predispositions also play a role in the development of cancer.</div><div><a href="https://cancerscience.net/knowledgebase/what-are-the-common-types-of-cancer" title="What Are the Common Types of Cancer?"><h3>What Are the Common Types of Cancer?</h3></a>Some of the most common types of cancer include <a href="https://cancerscience.net/about/index/lung-cancer" title="lung cancer" target="_blank">lung cancer</a>, <a href="https://cancerscience.net/about/index/breast-cancer" title="breast cancer" target="_blank">breast cancer</a>, <a href="https://cancerscience.net/about/index/prostate-cancer" title="prostate cancer" target="_blank">prostate cancer</a>, and <a href="https://cancerscience.net/about/index/colorectal-cancer" title="colorectal cancer" target="_blank">colorectal cancer</a>. Each type has its own risk factors, symptoms, and treatment options.</div><div><a href="https://cancerscience.net/knowledgebase/what-are-the-symptoms-of-cancer" title="What Are the Symptoms of Cancer?"><h3>What Are the Symptoms of Cancer?</h3></a>The symptoms of cancer can vary widely depending on the type and location of the cancer. Common symptoms include unexplained weight loss, persistent fatigue, pain, skin changes, and unusual lumps or masses. Early detection through <a href="https://cancerscience.net/about/index/screening" title="screening" target="_blank">screening</a> can improve the chances of successful treatment.</div><div><a href="https://cancerscience.net/knowledgebase/how-is-cancer-diagnosed" title="How is Cancer Diagnosed?"><h3>How is Cancer Diagnosed?</h3></a>The diagnosis of cancer often involves a combination of <a href="https://cancerscience.net/about/index/diagnostic-tests" title="diagnostic tests" target="_blank">diagnostic tests</a> such as imaging scans (e.g., X-rays, CT scans, MRI), blood tests, and biopsies. A biopsy, where a sample of tissue is examined under a microscope, is typically necessary to confirm a cancer diagnosis.</div><div><a href="https://cancerscience.net/knowledgebase/what-are-the-treatment-options-for-cancer" title="What Are the Treatment Options for Cancer?"><h3>What Are the Treatment Options for Cancer?</h3></a>Treatment options for cancer depend on the type, location, and stage of the disease. Common treatments include <a href="https://cancerscience.net/about/index/surgery" title="surgery" target="_blank">surgery</a> to remove tumors, <a href="https://cancerscience.net/about/index/radiation-therapy" title="radiation therapy" target="_blank">radiation therapy</a> to destroy cancer cells, and <a href="https://cancerscience.net/about/index/chemotherapy" title="chemotherapy" target="_blank">chemotherapy</a> to target rapidly dividing cells. Other treatments, such as <a href="https://cancerscience.net/about/index/immunotherapy" title="immunotherapy" target="_blank">immunotherapy</a> and <a href="https://cancerscience.net/about/index/targeted-therapy" title="targeted therapy" target="_blank">targeted therapy</a>, are designed to boost the body's immune system or target specific molecules involved in cancer growth.</div><div><a href="https://cancerscience.net/knowledgebase/what-is-the-prognosis-for-cancer-patients" title="What is the Prognosis for Cancer Patients?"><h3>What is the Prognosis for Cancer Patients?</h3></a>The prognosis for cancer patients varies widely based on factors such as the type and stage of cancer, the patient's overall health, and the effectiveness of treatment. Early detection and advances in treatment have improved the prognosis for many types of cancer. However, some cancers remain challenging to treat and have lower survival rates.</div><div><a href="https://cancerscience.net/knowledgebase/how-can-cancer-be-prevented" title="How Can Cancer Be Prevented?"><h3>How Can Cancer Be Prevented?</h3></a>While not all cancers can be prevented, certain lifestyle changes can reduce the risk of developing cancer. These include avoiding tobacco, limiting alcohol consumption, maintaining a healthy diet and weight, staying physically active, and protecting skin from excessive sun exposure. Regular <a href="https://cancerscience.net/about/index/screening-tests" title="screening tests" target="_blank">screening tests</a> can also help detect cancer early when it is most treatable.</div><div><a href="https://cancerscience.net/knowledgebase/what-are-the-latest-advances-in-cancer-research" title="What Are the Latest Advances in Cancer Research?"><h3>What Are the Latest Advances in Cancer Research?</h3></a>Recent advances in cancer research have led to the development of new treatments and diagnostic tools. <a href="https://cancerscience.net/about/index/precision-medicine" title="Precision medicine" target="_blank">Precision medicine</a>, which tailors treatments based on an individual's genetic makeup, is one of the most promising areas of research. Other advances include the use of <a href="https://cancerscience.net/about/index/liquid-biopsies" title="liquid biopsies" target="_blank">liquid biopsies</a> for early detection and monitoring, and the development of new <a href="https://cancerscience.net/about/index/immunotherapy-drugs" title="immunotherapy drugs" target="_blank">immunotherapy drugs</a> that harness the body's immune system to fight cancer.</div><div><h3>Conclusion</h3>Cancer remains a major global health challenge, but ongoing research and advancements in treatment are improving outcomes for many patients. Understanding the basics of cancer, recognizing symptoms, and seeking early diagnosis and treatment can significantly impact the prognosis and quality of life for those affected by this complex disease.</div></div> </div> <div id="recent_papers"> <br><hr /><br><h2 class="heading1">Relevant Publications</h2> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38787726" target='_blank' title="Dark force rising: Reawakening and targeting of fetal-like stem cells in colorectal cancer.">Dark force rising: Reawakening and targeting of fetal-like stem cells in colorectal cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38764305" target='_blank' title="Relationship Between Preoperative Nutritional Indicators and Postoperative Complications in Patients with Oesophageal Cancer: A Meta-Analysis.">Relationship Between Preoperative Nutritional Indicators and Postoperative Complications in Patients with Oesophageal Cancer: A Meta-Analysis.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38944844" target='_blank' title="Molecular profile of driver genes in lung adenocarcinomas of Brazilian patients who have never smoked: implications for targeted therapies.">Molecular profile of driver genes in lung adenocarcinomas of Brazilian patients who have never smoked: implications for targeted therapies.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38944901" target='_blank' title="Development of a bioluminescent homogenous nanobody-based immunoassay for the detection of prostate-specific antigen (PSA).">Development of a bioluminescent homogenous nanobody-based immunoassay for the detection of prostate-specific antigen (PSA).</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38925848" target='_blank' title="NUAK2 Inhibitors, KHKI-01128 and KHKI-01215, Exhibit Potent Anticancer Activity Against SW480 Colorectal Cancer Cells.">NUAK2 Inhibitors, KHKI-01128 and KHKI-01215, Exhibit Potent Anticancer Activity Against SW480 Colorectal Cancer Cells.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38925350" target='_blank' title="Discovery and validation of combined biomarkers for the diagnosis of esophageal intraepithelial neoplasia and esophageal squamous cell carcinoma.">Discovery and validation of combined biomarkers for the diagnosis of esophageal intraepithelial neoplasia and esophageal squamous cell carcinoma.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38944939" target='_blank' title="A self-immobilizing near-infrared fluorogenic probe for in vivo imaging of fibroblast activation protein-伪.">A self-immobilizing near-infrared fluorogenic probe for in vivo imaging of fibroblast activation protein-伪.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945528" target='_blank' title="Colon cancer-associated transcript 1 (CCAT1): A potential novel target in cancer therapy.">Colon cancer-associated transcript 1 (CCAT1): A potential novel target in cancer therapy.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38944945" target='_blank' title="Adverse selection and network design under regulated plan prices: Evidence from Medicaid.">Adverse selection and network design under regulated plan prices: Evidence from Medicaid.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945908" target='_blank' title="[Pharmacological properties and clinical development overview of pertuzumab (genetical recombination), trastuzumab (genetical recombination) and vorhyaluronidase alfa (genetical recombination) (PHESGO combination for 鈥峴ubcutaneous injection MA, IN)].">[Pharmacological properties and clinical development overview of pertuzumab (genetical recombination), trastuzumab (genetical recombination) and vorhyaluronidase alfa (genetical recombination) (PHESGO combination for 鈥峴ubcutaneous injection MA, IN)].</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38945700" target='_blank' title="Recent advances and molecular mechanisms of TGF-尾 signaling in colorectal cancer, with focus on bioactive compounds targeting.">Recent advances and molecular mechanisms of TGF-尾 signaling in colorectal cancer, with focus on bioactive compounds targeting.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946012" target='_blank' title="Subdivision of pT1N0 (American Joint Committee on Cancer 8th edition) distal cholangiocarcinoma for adjuvant chemotherapy consideration.">Subdivision of pT1N0 (American Joint Committee on Cancer 8th edition) distal cholangiocarcinoma for adjuvant chemotherapy consideration.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946063" target='_blank' title="14-3-3 Family of Proteins: Biological Implications, Molecular Interactions, and Potential Intervention in Cancer, Virus and Neurodegeneration Disorders.">14-3-3 Family of Proteins: Biological Implications, Molecular Interactions, and Potential Intervention in Cancer, Virus and Neurodegeneration Disorders.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946034" target='_blank' title="WGCNA reveals a biomarker for cancer-associated fibroblasts to predict prognosis in cervical cancer.">WGCNA reveals a biomarker for cancer-associated fibroblasts to predict prognosis in cervical cancer.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946231" target='_blank' title="The impact of hysterectomy on subsequent colonoscopy in women with Lynch Syndrome.">The impact of hysterectomy on subsequent colonoscopy in women with Lynch Syndrome.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946003" target='_blank' title="From balance to imbalance: disruption of plasma glutathione concentration in micropapillary thyroid carcinoma.">From balance to imbalance: disruption of plasma glutathione concentration in micropapillary thyroid carcinoma.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946317" target='_blank' title="Maternal Substance Use and Childhood Cancer-Letter.">Maternal Substance Use and Childhood Cancer-Letter.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946284" target='_blank' title="Dense tumor-infiltrating lymphocytes (TILs) in liver metastasis from colorectal cancer are related to improved overall survival.">Dense tumor-infiltrating lymphocytes (TILs) in liver metastasis from colorectal cancer are related to improved overall survival.</a> </div> <p><strong>Issue Release:</strong> 2024</p> </div> <div class='publication-block'> <div style='margin-bottom: 10px;line-height: 24px;'> <a href="https://pubmed.ncbi.nlm.nih.gov/38946429" target='_blank' title="A lateral flow assay strip for simultaneous detection of miRNA and exosomes in liver cancer.">A lateral flow assay strip 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