Closed Loop Large Bowel Obstruction Due to Appendiceal Signet Cell Carcinoma

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Obstruction Due to Appendiceal Signet Cell Carcinoma</title> <meta name="description" content="Closed Loop Large Bowel Obstruction Due to Appendiceal Signet Cell Carcinoma"> <meta name="keywords" content="appendiceal carcinoma, large bowel obstruction, signet ring cell cancer, caecal perforation"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img 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publication-listing mt-3 mb-3"> <h5 class="card-header" style="font-size:.9rem">Closed Loop Large Bowel Obstruction Due to Appendiceal Signet Cell Carcinoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Joshua%20Teo">Joshua Teo</a>, <a href="https://publications.waset.org/abstracts/search?q=Leo%20Phan"> Leo Phan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Signet cell carcinoma of the appendix is the rarest and the most aggressive subtype of appendiceal malignancy, typically with non-specific presentations. We describe a case of a 62-year-old male with large bowel obstruction and CT demonstrating dilated large bowels from caecum to proximal sigmoid colon with pneumoperitoneum. Intra-operatively, closed-loop obstruction caused by dense adherence of sigmoid colon to caecum was noted, which had resulted in caecal perforation. Histopathology study indicated primary appendiceal malignancy of signet cell morphology with intra-peritoneal spread to the sigmoid colon. Large bowel obstruction from appendiceal malignancy has rarely been reported, and a similar presentation has not been described in the existing literature. When left-sided large bowel obstruction is suspected to be caused by a malignant stricture, it is essential to consider transperitoneal spread of appendiceal malignancy as potential aetiology, particularly in the elderly. <iframe src="https://publications.waset.org/abstracts/141362.pdf" style="width:100%; height:400px;" frameborder="0"></iframe> <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=appendiceal%20carcinoma" title="appendiceal carcinoma">appendiceal carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=large%20bowel%20obstruction" title=" large bowel obstruction"> large bowel obstruction</a>, <a href="https://publications.waset.org/abstracts/search?q=signet%20ring%20cell%20cancer" title=" signet ring cell cancer"> signet ring cell cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=caecal%20perforation" title=" caecal perforation"> caecal perforation</a> </p> <a 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Closed Loop Large Bowel Obstruction Due to Appendiceal Signet Cell Carcinoma