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href="/research-funding/research-resources/data-management-sharing">NIDDK Data Management & Sharing</a> </li> </ul> </li> <li class="ln-current"> <div> <span>Technology Advancement & Transfer</span> <button type="button">Hide child pages</button></div> <ul> <li class="ln-collapsed"> <a href="/research-funding/technology-advancement-transfer/research-materials-licensing">Research Materials & Licensing</a> </li> <li class="ln-collapsed"> <a href="/research-funding/technology-advancement-transfer/clinical-trial-collaboration">Clinical Trial Collaboration</a> </li> <li class="ln-collapsed"> <a href="/research-funding/technology-advancement-transfer/research-collaboration">Research Collaboration</a> </li> </ul> </li> </ul> </nav> <article class="dk-content"> <h1 itemprop="name">Technology Advancement & Transfer</h1> <div > <p>NIDDK is committed to transferring its technologies and research materials through industry partnerships to benefit public health. The <a href="/about-niddk/offices-divisions/technology-advancement-office">NIDDK Technology Advancement Office (TAO)</a> facilitates the exchange, evaluation, patenting, and licensing of new inventions and discoveries. If you have any questions, contact the <a href="mailto:tao@niddk.nih.gov">Technology Advancement Office</a>.</p> <h2>TAO Supports</h2> <ul class="thumbnail-list"> <li><i class="stack-icon green blank grant-award"></i> <div class="title"><a href="/research-funding/technology-advancement-transfer/research-materials-licensing">Research Materials and Licensing</a></div> <div> <p>Use research materials and reagents, Material Transfer Agreements (MTAs), and licensing opportunities developed by NIDDK scientists for your research.</p> </div> </li> <li><i class="stack-icon orange blank medical-microscope"></i> <div class="title"><a href="/research-funding/technology-advancement-transfer/clinical-trial-collaboration">Clinical Trial Collaboration</a></div> <div> <p>Collaborate with investigators at the NIH Clinical Center and NIDDK extramural clinical networks on clinical trials.</p> </div> </li> <li><i class="stack-icon indigo blank collaboration"></i> <div class="title"><a href="/research-funding/technology-advancement-transfer/research-collaboration">Research Collaboration</a></div> <div> <p>Connect with NIDDK clinicians or scientists in your field and locate technologies available for further development.</p> </div> </li> </ul> </div> <section class="sc-slider "> <div class="grid"> <h2>NIDDK Technology Highlights</h2> </div> <div class="sc-inner-wrap"> <div class="sc-slider-paginator"> <button type="button" class="sc-previous" aria-label="Show previous cards"></button> <button type="button" class="sc-next" aria-label="Show next cards"></button> </div> <div class="grid"> <div class="sc-cards"> <div class="sc-card"> <a href="/research-funding/technology-advancement-transfer/research-materials-licensing/a3-adenosine-receptor-positive-allosteric-modulators"> <div class="sc-card-image"><img src="/-/media/Images/Research-Funding/Technology-Advancement-Transfer/NOV23_Diagram2.jpg?as=0&h=300&iar=0&w=400&hash=6FC98A3C5316042826071BB60D385B3E" alt="A diagram of A3 Adenosine Receptor Positive Allosteric Modulators" width="400" height="300"/></div> <div class="sc-card-header">A3 Adenosine Receptor Positive Allosteric Modulators</div> <div class="sc-card-copy"> <p>Invention relates to allosteric modulation of A3 adenosine receptor (A3AR).</p> </div> </a> </div> <div class="sc-card"> <a href="/research-funding/technology-advancement-transfer/research-materials-licensing/heterocyclic-p2y14-antagonists"> <div class="sc-card-image"><img src="/-/media/Images/Research-Funding/Technology-Advancement-Transfer/NOV23_Diagram1.jpg?as=0&h=300&iar=0&w=400&hash=CE3085FBE9F224BD2ED90195BCC2C94F" alt="Diagram of Heterocyclic P2Y14 Antagonists for the Treatment of Various Conditions" width="400" height="300"/></div> <div class="sc-card-header">Heterocyclic P2Y14 Antagonists for the Treatment of Various Conditions</div> <div class="sc-card-copy"> <p>Composition of highly selective P2Y14 receptor antagonists, as potential therapeutics for asthma, chronic pain, inflammation and diabetes and neurodegeneration.</p> </div> </a> </div> <div class="sc-card"> <a href="/research-funding/technology-advancement-transfer/research-materials-licensing/personalized-body-weight-management-system"> <div class="sc-card-image"><img src="/-/media/Images/Components/Cards/PBWC-Screen-for-TAO-Slider.png?as=0&h=300&iar=0&w=400&hash=5BC54510ACF0A7161292D6CF17E15109" alt="PBWC Slider Image" width="400" height="300"/></div> <div class="sc-card-header">Personalized Body Weight Management System</div> <div class="sc-card-copy"> <p>A licensable system to establish, track and adjust clinical weight management interventions over time. Accounts for changes in human appetite, metabolism, and calorie expenditure. Builds on the research behind the Body Weight Planner.</p> </div> </a> </div> <div class="sc-card"> <a href="/research-funding/technology-advancement-transfer/research-materials-licensing/dna-sequence-insulator-cis-acting"> <div class="sc-card-image"><img src="/-/media/Images/Components/Cards/DNA-Sequence-400x300b.png?as=0&h=300&iar=0&w=400&hash=352A29BA06D941890EE7E0AD5C60057E" alt="A diagram showing cell type differences inside DNA sequences." width="400" height="300"/></div> <div class="sc-card-header">5′-HS4 chicken β-globin insulator (DNA sequence acting as an insulator for the effects of cis-acting regulatory elements)</div> <div class="sc-card-copy"> <p>A newly characterized chromatin insulator element isolated from the DNA of a higher eukaryotic organism and contained in vector constructs is described...</p> </div> </a> </div> <div class="sc-card"> <a href="/research-funding/technology-advancement-transfer/research-materials-licensing/sphk1-ko-mouse"> <div class="sc-card-image"><img src="/-/media/Images/Components/Cards/mouse-helix-400x300.png?as=0&h=300&iar=0&w=400&hash=C7688CB41F72C43C07C540020BBC1F6F" alt="A mouse with a DNA Helix symbol" width="400" height="300" loading="lazy"/></div> <div class="sc-card-header">Sphk1 KO</div> <div class="sc-card-copy"> <p>A Sphingosine kinase 1 (Sphk1) knockout mouse… </p> </div> </a> </div> <div class="sc-card"> <a href="/research-funding/technology-advancement-transfer/research-materials-licensing/stat5a-loxp-mouse"> <div class="sc-card-image"><img src="/-/media/Images/Components/Cards/Stat5-Hen-400x300.png?as=0&h=300&iar=0&w=400&hash=2336956BD6AA7C85406871158B878DB6" alt="Visual representation of the Stat5a LoxP/Stat5b LoxP protein." width="400" height="300" loading="lazy"/></div> <div class="sc-card-header">Stat5a LoxP/Stat5b LoxP (Stat5a/Stat5b tm2Mam)</div> <div class="sc-card-copy"> <p>Conditional knockout of Stat5a and Stat5b: Combined deletion of conserved Stat5a and Stat5b in mammary<br/>epithelium at different times during pregnancy reveal multiple distinct functions...</p> </div> </a> </div> </div> </div> </div> </section> <h2>Related Links</h2> <ul class="thumbnail-list"> <li><i class="stack-icon green square test-tubes"></i> <div class="title"><a href="/research-funding/at-niddk/labs-branches">Laboratories and Branches at NIDDK</a></div> <div> <p> </p> </div> </li> <li><i class="stack-icon orange circle id-badge"></i> <div class="title"><a href="/research-funding/at-niddk/faculty">Intramural NIDDK Faculty</a></div> <div> <p> </p> </div> </li> <li><i class="stack-icon small-business indigo hexagon"></i> <div class="title"><a href="/research-funding/research-programs/small-business">Small Business Programs</a></div> <div> <p> </p> </div> </li> <li><i class="stack-icon square blue lightbulb"></i> <div class="title"><a href="/about-niddk/offices-divisions/technology-advancement-office">NIDDK Technology Advancement Office</a></div> <div> <p> </p> </div> </li> </ul> <h2>NIH Resources</h2> <ul class="thumbnail-list"> <li><i class="stack-icon green pentagon-arrow handshake"></i> <div class="title"><a href="https://www.ott.nih.gov/">NIH Office of Technology Transfer</a></div> <div> <p> </p> </div> </li> <li><i class="stack-icon pentagon-arrow orange newspaper"></i> <div class="title"><a href="https://www.ott.nih.gov/rss">OTT Recent News</a></div> <div> <p> </p> </div> </li> <li><i class="stack-icon pentagon-arrow indigo medical-microscope"></i> <div class="title"><a href="https://irp.nih.gov/">NIH Intramural Research Program</a></div> <div> <p> </p> </div> </li> <li><i class="stack-icon pentagon-arrow blue grant-award"></i> <div class="title"><a href="https://www.ott.nih.gov/opportunities">OTT Licensing Opportunities</a></div> <div> <p> </p> </div> </li> </ul> <div class="dk-review-date">Last Reviewed September 2024</div> </article> </div> </div> </main> <footer id="main-footer" itemscope 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