Transforming clinical trials to improve Pharma ROI

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As sponsor strategies change, ICON’s blended solutions offer models that meet their needs.</p></div> </div> </div> </div> </div> </a> </div> <div class="col-sm"> <a href="/insights/transforming-trials/partnership-insights" class="block-link" target="_self"> <div class="container-full"> <div class="card card--title-description card--title-description-purple text-left"> <div class="card-body" data-mh="card-body"> <i class="icon-ui-arrow-right"></i> <h4 class="card-title">Partnering to improve outcomes</h4> <div class="card-text small"> <div> <p>Much more can be achieved when the life sciences and pharmaceutical industries truly collaborate. At ICON, this means working in a way that goes beyond a traditional CRO. It means being a trusted partner.</p> </div> </div> </div> </div> </div> </a> </div> </div> </div> </div> </div> <div id="a330fb79-96e7-4bb6-a211-bab755a71e47"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> </h3> <div> <p class="lead">Designed primarily to meet regulatory requirements for therapies targeting large patient populations, the existing development model lacks the flexibility, analytical power and efficiency to address today’s development demands.</p> <p>These include managing product pipelines targeting smaller and more heterogeneous indications, meeting rising standards of evidence from payers that are moving towards value-based reimbursement models, and addressing the patient’s rising role in care decisions.</p> <p>Our industry must adopt an entirely new framework for development infrastructure and processes. Focus must go beyond cost containment alone, and instead unlock value through fundamental reforms that allow sponsors to move more treatments to market faster.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="547ab95c-f2a7-4b69-9935-bdca3a8f46f7"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/icxhdkf3bg/web/COA-whitepaper-subpage-banner.png?crop=yes&w=622&h=380&a=818,0&itok=8R9d2gSg 1x, https://icon.widen.net/content/icxhdkf3bg/web/COA-whitepaper-subpage-banner.png?crop=yes&w=622&h=380&a=818,0&itok=8R9d2gSg 2x" media="(min-width: 1400px)" width="555" height="339"/> <source 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height="339"/> <source srcset="https://icon.widen.net/content/icxhdkf3bg/web/COA-whitepaper-subpage-banner.png?crop=yes&w=622&h=380&a=818,0&itok=8R9d2gSg 1x, https://icon.widen.net/content/icxhdkf3bg/web/COA-whitepaper-subpage-banner.png?crop=yes&w=622&h=380&a=818,0&itok=8R9d2gSg 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/icxhdkf3bg/web/COA-whitepaper-subpage-banner.png?crop=yes&w=622&h=380&a=818,0&itok=8R9d2gSg 1x, https://icon.widen.net/content/icxhdkf3bg/web/COA-whitepaper-subpage-banner.png?crop=yes&w=622&h=380&a=818,0&itok=8R9d2gSg 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/icxhdkf3bg/web/COA-whitepaper-subpage-banner.png" width="1440" height="380" alt="COA-whitepaper-subpage-banner" title="COA-whitepaper-subpage-banner" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2></h2> <h3>Ensuring the validity of clinical outcomes assessment data: The value of rater training</h3> <div><p>The necessity of appropriately training raters for reducing variability in measurements, rater interpretation, and bias and scale administration errors in COA implementation are outlined in this whitepaper.</p></div> <a class="btn btn-primary btn-md" href="https://www.iconplc.com/insights/transforming-trials/ensuring-validity-clinical-outcomes-assessment-coa-data-value-rater" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="970dc43b-e29b-4db0-90d8-2601ca0dc4f8"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid 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https://icon.widen.net/content/hgghmygyuu/web/Optimising%20biotech%20funding%20whitepaper%20series_1440x750.jpg?crop=yes&w=1228&h=750&a=212,0&itok=SZDkvcEA 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/hgghmygyuu/web/Optimising%20biotech%20funding%20whitepaper%20series_1440x750.jpg?crop=yes&w=1228&h=750&a=212,0&itok=SZDkvcEA 1x, https://icon.widen.net/content/hgghmygyuu/web/Optimising%20biotech%20funding%20whitepaper%20series_1440x750.jpg?crop=yes&w=1228&h=750&a=212,0&itok=SZDkvcEA 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/hgghmygyuu/web/Optimising%20biotech%20funding%20whitepaper%20series_1440x750.jpg" width="1440" height="750" alt="Optimising biotech funding whitepaper series_1440x750" title="Optimising biotech funding whitepaper series_1440x750" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2>Optimising biotech funding whitepaper series</h2> <h3></h3> <div><p>In this two-part whitepaper series on biotech funding, we firstly share insights on how biotechs can secure funding in a highly competitive market, and then shed light on the opportunities available to utilise these funds more effectively and efficiently.</p></div> <a class="btn btn-primary btn-md" href="/insights/transforming-trials/optimising-biotech-funding" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="9d664fe8-fdcf-4eb3-9703-6918b1c67097"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 1x, https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 1x, https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 1x, https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 1x, https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 1x, https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 1x, https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg?crop=yes&w=982&h=600&a=938,0&itok=hovINtC3 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/4jx7oxlq7u/web/whitepaper-innovative-tools-reg-writing.jpg" width="1920" height="600" alt="whitepaper-innovative-tools-reg-writing" title="whitepaper-innovative-tools-reg-writing" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2>Using innovative tools and lean writing processes to accelerate regulatory document writing</h2> <h3></h3> <div><p>In this whitepaper, we explore how these valuable tools, including software, templates and collaborative work processes, can provide practical solutions to common challenges medical writers face.</p></div> <a class="btn btn-primary btn-md" href="/insights/regulatory-intelligence/accelerate-regulatory-document-writing" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="5a6fcf6a-6a5c-427d-81bd-bd7bdeeaf915"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 1x, https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 1x, https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 1x, https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 1x, https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 1x, https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 1x, https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg?crop=yes&w=622&h=380&a=818,0&itok=CO2Jim7- 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/735nvusf6c/web/moneymolecules_banner.jpg" width="1440" height="380" alt="moneymolecules_banner" title="moneymolecules_banner" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2>2023 biotech sector survey</h2> <h3>Navigating biotech's challenges and embracing a promising tomorrow</h3> <div><p>Using exclusive data from ICON’s 2023 survey with Citeline, this report presents valuable insights from 133 influential decision-makers within biotech and venture capital organisations from across North America, Europe, and Asia Pacific.</p></div> <a class="btn btn-primary btn-md" href="https://www.iconplc.com/insights/transforming-trials/accelerating-biotech-innovation" target="_self" title="Read the report"> Read the report </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="815c07e6-b73c-4efc-8d7b-c2827699f5fc"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"><img src="https://icon.widen.net/content/b4kgaltwic/original/Linguistic-validation-coa.jpg?u=z8skf3" alt="Linguistic-validation-coa" title="Linguistic-validation-coa" /> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2>Linguistic validation of clinical outcomes assessments:</h2> <h3>A best-practice approach </h3> <div><p>In this whitepaper we describe the rigorous, iterative linguistic validation process for COAs that ensures conceptual equivalency and cultural relevance for each required translation. </p></div> <a class="btn btn-primary btn-md" href="/insights/transforming-trials/linguistic-validation-of-clinical-outcomes-assessments" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="cfdaf6b6-f427-4dca-bb4d-be25b2d894ad"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"><img src="https://icon.widen.net/content/aczdxveua5/original/Whitepaper-Digitizing-COAs.jpg?u=z8skf3" alt="Whitepaper-Digitizing COAs" title="Whitepaper-Digitizing COAs" /> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2>Digitizing COAs: A streamlined approach to approval</h2> <h3></h3> <div><p>In all aspects of life, paper copies are giving way to electronic versions of documents. Clinical research is no exception as there is an ongoing push to capture trial data electronically to improve both the participant experience and data quality. Download the whitepaper from Mapi Research Trust to discover success factors in converting from paper to digital.</p></div> <a class="btn btn-primary btn-md" href="https://mapi-trust.org/resources/whitepapers/digitizing-coas/" target="_blank" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="e46eb0f6-7f6a-4163-ae86-6bbd6865844b"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 1x, https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 1x, https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 1x, https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 1x, https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 1x, https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 1x, https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg?crop=yes&w=555&h=339&a=0,0&itok=vvN8fRq2 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/0odtjdaf3u/web/Whitepaper-COA-licensing_image_rev.jpg" width="555" height="339" alt="Whitepaper-COA-licensing_image_rev" title="Whitepaper-COA-licensing_image_rev" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2>The COA licensing process: How to prepare for success</h2> <h3></h3> <div> <p>The prerequisites for controlled use of Clinical Outcome Assessments (COAs) and suggestions for streamlining the licensing process, which can be complex and typically involves multiple parties, are detailed in this whitepaper from Mapi Research Trust.</p> <p> </p> </div> <a class="btn btn-primary btn-md" href="https://mapi-trust.org/resources/whitepapers/coa-licensing-process/index.xml" target="_blank" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="27a686c4-7f53-4669-8291-759a05d2b105"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 1x, https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 1x, https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 1x, https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 1x, https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 1x, https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 1x, https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg?crop=yes&w=555&h=339&a=0,0&itok=9dcpCQCE 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/3mfflexgiz/web/eCOA.jpg" width="555" height="339" alt="eCOA" title="eCOA" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2>Keeping eCOA implementation off a trial’s critical path</h2> <h3>A best-practice approach</h3> <div> <p>In this whitepaper we describe what is involved in adopting an eCOA solution and share a recommended approach to planning and implementing eCOA that will eliminate surprises and mitigate the risks of delaying the study start up.</p> <p><a href="https://international-pharma.com/keeping-ecoas-off-the-critical-path-key-considerations/" target="_blank">Related article on eCOA.</a></p> </div> <a class="btn btn-primary btn-md" href="/insights/transforming-trials/ecoa-implementation" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="26f10b19-d793-48e8-89c3-9962dba8684b"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 1x, https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 1x, https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 1x, https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 1x, https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 1x, https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 1x, https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=_WJoYCtX 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/jeaqbm2lnk/web/Best-practices-to-increase-engagement-555x339.jpg" width="555" height="339" alt="Best-practices-to-increase-engagement-555x339" title="Best-practices-to-increase-engagement-555x339" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2></h2> <h3>Whitepaper: Best practices to increase engagement with medical and scientific poster content</h3> <div> <p>Scientific posters are in need of a design overhaul. Poster sessions are a valuable opportunity to communicate research with a large audience. However, traditional posters rely on an information-dense design and often fail to make a lasting impression.</p> </div> <a class="btn btn-primary btn-md" href="/insights/transforming-trials/best-practices-to-increase-engagement-with-medical-and-scientific-poster-content" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="393bb978-f1d1-465f-979e-71c86450ea4e"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 1x, https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 1x, https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 1x, https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 1x, https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 1x, https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 1x, https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg?crop=yes&w=257&h=157&a=43,0&itok=FG282UQM 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/gjhdwwopcb/web/7876_ICON_RBQM_MDD.jpg" width="300" height="157" alt="7876_ICON_RBQM_MDD" title="7876_ICON_RBQM_MDD" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2></h2> <h3>Risk Based Quality Management</h3> <div> <p>Our risk based, patient focused methodology for the design and execution of an adaptive monitoring strategy already has a quality management system, risk management system and innovative proprietary technology to support implementation of new ICH GCP guidelines.</p> </div> <a class="btn btn-primary btn-md" href="/insights/transforming-trials/risk-based-quality-management" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="39dfc904-4dda-419c-b708-39e02873e0a5"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 1x, https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 1x, https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 1x, https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 1x, https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 1x, https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 1x, https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg?crop=yes&w=318&h=194&a=36,0&itok=2JMIRhub 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/kuf14mrbty/web/Monitoring-in-a-post-covid-era-website-images_Page-tiles.jpg" width="370" height="194" alt="Monitoring-in-a-post-covid-era-website-images_Page-tiles" title="Monitoring-in-a-post-covid-era-website-images_Page-tiles" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2></h2> <h3>Agile clinical monitoring </h3> <div> <p>Our whitepaper examines how agile clinical monitoring provides the flexibility to keep your trials on track.</p> <p>Topics include:</p> <ul> <li>The changing dynamic of clinical monitoring</li> <li>Assessing models for quality and flexibility</li> <li>Considerations in Remote monitoring</li> <li>Integrated technology strategy</li> <li>Hybrid monitoring model – the model for the future</li> </ul> </div> <a class="btn btn-primary btn-md" href="/insights/patient-centricity/agile-clinical-monitoring" target="_self" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="e5888138-8fa3-4c11-b36c-2c895db1af6d"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 1x, https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 1x, https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 1x, https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 1x, https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 1x, https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 1x, https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg?crop=yes&w=555&h=339&a=0,0&itok=aVAY8HqC 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/fmxt0fkemu/web/roi-in-drug-development-insights.jpg" width="555" height="339" alt="roi-in-drug-development-insights" title="roi-in-drug-development-insights" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2></h2> <h3>Increasing complexity and declining ROI in drug development</h3> <div> <p>Find out more about how other organisations such as TEVA and UCB Biosciences are managing the evolving challenges of drug development and read the insights of an eminent doctor who has a unique perspective due to his varying roles in the industry.</p> <p>Topics covered in the report:</p> <ul> <li>Is increasing complexity, reality or myth?</li> <li>Complexity: a necessary evil or is there a better way?</li> <li>Drug development with fresh eyes and new perspectives</li> <li>Patient power and dynamics</li> <li>Engaging the investigator for better outcomes</li> <li>Virtual trials – extending the reach of clinical trials Areas of focus to decrease the cost of R&D</li> </ul> </div> <a class="btn btn-primary btn-md" href="/insights/transforming-trials/increasing-complexity-and-declining-roi-in-drug-development" target="_self" title="Read the report"> Read the report </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="f189c7fa-837a-47f2-a776-195e08eae202"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <a class="text-picture-link-wrapper" target="_top" href="/insights/transforming-trials/innovation-in-clinical-trial-methodologies"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 1x, https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 1x, https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 1x, https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 1x, https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 1x, https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 1x, https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg?crop=yes&w=982&h=600&a=520,0&itok=x_YjeXpQ 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/6ulzxospwr/web/DtX_Payer_Perspective_web_Subpage.jpg" width="1920" height="600" alt="DtX_Payer_Perspective_web_Subpage" title="DtX_Payer_Perspective_web_Subpage" loading="lazy" /> </picture> </div> </div> </a> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2></h2> <h3>Innovation in clinical trial methodologies</h3> <div> <p>In a timely new book edited by Dr Peter Schueler, Senior VP Drug Development Services, Neurosciences, at ICON plc, authors explore how, by learning the right lessons, the industry and wider society could be entering a golden age of drug development. </p> <p>ICON is pleased to offer a code for a 30% discount on individual purchases, and a 50% discount on bulk purchases (more than 10) – simply complete the short form to receive your discount code and link to purchase the book.</p> </div> <a class="btn btn-primary btn-md" href="/insights/transforming-trials/innovation-in-clinical-trial-methodologies" target="_self" title="Receive your discount"> Receive your discount </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="a3b9ff24-3bdc-4b2a-9e3e-2db94c0698de"> <div class="bg-gray"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h3> Digital disruption in pharma and the need to transform clinical trials </h3> <div> <p>ICON's Dr. Greg Licholai, Chief Medical & Innovation Officer took part in a panel discussion: Dynamic clinical trial models at the 2022 Financial Times US Pharma and Biotech Summit. The panel discussion covered a wide range of topics including how the COVID-19 pandemic accelerated innovation in clinical trials, especially in terms of how to connect with patients and investigators.</p> <p>The challenges of the pandemic have pushed CROs and sponsors to embrace new ways of conducting clinical trials that offer significant advantages going forward. At the 2021 Financial Times US Pharma and Biotech Summit, ICON CEO Dr. Steve Cutler discussed these developments in a post-pandemic clinical trials landscape and recent developments in the CRO market.</p> <p>Watch ICON’s CIO, Tom O’Leary in conversation with Hannah Kuchler, US Pharma and Biotech Correspondent discuss digital disruption in pharma and the need to transform clinical trials. Recorded late November 2019 at the Financial Times Global Pharmaceutical and Biotechnology conference in London.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div><div id="4a3090d8-3a83-42f9-bd12-c10b8751dca2"> <div class="container-fluid container-fluid--xl"> <div class="video-player video-player--with-playlist"> <video id="player-1699498587582178024" data-playlist-id="1699498587582178024" data-account="108289197001" data-player="default" data-embed="default" data-application-id="" class="video-js" controls=""> </video> <script src="//players.brightcove.net/108289197001/default_default/index.min.js"></script> <div class="vjs-playlist"></div> <script src="https://players.brightcove.net/videojs-bc-playlist-ui/3/videojs-bc-playlist-ui.min.js"></script> <script type="text/javascript"> videojs.getPlayer('player-1699498587582178024').ready(function() { // Get a reference to the player var myPlayer = this, // Create an object in which you will place options options = {}; // Set options options.horizontal = true; options.autoadvance = 0; // Call plugins method passing in options object myPlayer.bcPlaylistUi(options); }); </script> <div class="video-label"></div> </div> </div> </div> <div id="804fa732-b9c3-4463-b1f7-23c30af02693"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 1x, https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 1x, https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 1x, https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 1x, https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 1x, https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 1x, https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient?crop=yes&w=555&h=339&a=0,0&itok=hM8G3PsJ 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/qnzivov9xp/web/doctor-with-patient" width="555" height="339" alt="doctor-with-patient" title="doctor-with-patient" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2></h2> <h3>ICON’s Transforming Trials initiative is a continuous quality improvement process that</h3> <div> <ul> <li>Confronts fundamental risks that cause high failure rates</li> <li>Disrupts inefficient processes with EHR-driven analytics</li> <li>Integrates payer, provider, and patient priorities at early decision-points</li> <li>Accelerates precision medicine and development for rare and orphan indications</li> <li>Leverages mobile technologies both to enhance trials and support a product ecosystem</li> <li>Facilitates a continuously learning clinical ecosystem</li> </ul> <p>Much of the foundational innovation needed to transform clinical development enterprise exists today, and enjoys explicit regulatory support.</p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="f7cb290e-3329-4ef9-9cf4-99455d530383"> <div class="bg-gray"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 1x, https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 1x, https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 1x, https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 1x, https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 1x, https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 1x, https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials?crop=yes&w=555&h=339&a=0,0&itok=RgukN9dU 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/y5ecwxzw7t/web/whitepaper-transforming-trials" width="555" height="339" alt="whitepaper-transforming-trials" title="whitepaper-transforming-trials" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2></h2> <h3>Improving Pharma R&D efficiency</h3> <div> <p>The cost pressures on drug development are driving the search for savings. Whilst large-scale operational efficiencies are being instituted in many pharmaceutical organisations, efforts need to be integrated if they are to be effective.</p> <ul> <li><a href="https://www.contractpharma.com/issues/2021-10-01/view_features/rd-outsourcing-trends-roundtable/?widget=listSection" target="_blank">Article: R&D outsourcing trends roundtable</a></li> <li><a href="https://pharmaphorum.com/views-analysis-digital/digital-reversing-fortunes-rd/" target="_blank">Article: How digital is reversing fortunes in R&D</a></li> <li><a href="/insights/transforming-trials/improving-pharma-research-and-development-efficiency/" target="_self">Improving Pharma R&D efficiency: The case for a holistic approach to transforming clinical trials</a></li> <li><a href="https://www2.iconplc.com/article/contractpharma/transforming_trials" target="_blank">Article: Improving Pharma R&D efficiency - the need to transform clinical trials (PDF)</a></li> <li><a href="http://www.appliedclinicaltrialsonline.com/improving-pharma-rd-efficiency?pageID=1" target="_blank">Article: Applied Clinical Trials: Improving Pharma R&D</a></li> <li>Webinar: <a href="/news-events/events/webinars/improving-r-and-d-efficiency-through-a-holistic-approach-to-clinical-trials/" target="_self">Improving R&D Efficiency - why 62% of companies are planning a holistic approach to transform clinical trials</a>.</li> </ul> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="17f3f5cb-e7b4-4506-a773-5b733d4b4988"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 1x, https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 1x, https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 1x, https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 1x, https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 1x, https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 1x, https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes?crop=yes&w=555&h=339&a=0,0&itok=IlAbxtkm 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/pit5p8mvnk/web/lab-test-tubes" width="555" height="339" alt="lab-test-tubes" title="lab-test-tubes" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2></h2> <h3>Adaptive Design</h3> <div><p>Adaptive designs remove unnecessary risk from trials, both for patients and sponsors. ICON combines powerful statistical methodologies with novel technology suites such as <a href="https://www.iconplc.com/solutions/technologies/flex-advantage/" target="_self">FLEXADVANTAGE</a> to design and execute efficient studies that mitigate problems that too often undermine good products.</p><ul><li><a href="/insights/transforming-trials/adaptive-clinical-trials/" target="_self">ICON guide to adaptive trials</a></li><li><a href="/insights/transforming-trials/adaptive-clinical-trials/faster-path-to-market/" target="_self">Adaptive design: The faster path to market for medical devices</a></li></ul></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="0c8075a6-4377-4ba8-9da0-9a6a283c6a16"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 1x, https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 1x, https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 1x, https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 1x, https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 1x, https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 1x, https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg?crop=yes&w=555&h=339&a=0,0&itok=WhiGO17L 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/t9apkvx4t8/web/Estimands-Whitepaper_555x339.jpg" width="555" height="339" alt="Estimands-Whitepaper_555x339" title="Estimands-Whitepaper_555x339" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2></h2> <h3>Bringing clarity and focus to the research question: the role of estimands</h3> <div> <p>The International Council for Harmonisation (ICH) guideline E9 Statistical Principles for Clinical Trials was issued in 1998 and in November 2019 an addendum to ICH E9 (R1) was issued relating to estimands and sensitivity analyses. This Whitepaper outlines the basics of estimands, and discusses their proposed deployment for improving the quality of clinical research.</p> </div> <a class="btn btn-primary btn-md" href="https://icon.widen.net/s/fcqkdkmpdf/estimands-whitepaper" target="_blank" title="Read the whitepaper"> Read the whitepaper </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="12226d11-558c-406a-a0f4-66c0a1652e89"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 1x, https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 1x, https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 1x, https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 1x, https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 1x, https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 1x, https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg?crop=yes&w=555&h=339&a=0,0&itok=ztIQYwlE 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/ydluz3iqh9/web/harnessing-technology-to-maximise-rwe-value.jpg" width="555" height="339" alt="harnessing-technology-to-maximise-rwe-value" title="harnessing-technology-to-maximise-rwe-value" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2></h2> <h3>Real World Intelligence™</h3> <div><p>Based on deep insights into emerging evidence needs, ICON experts design <a href="/solutions/real-world-intelligence/">real-world data collection strategies</a> that build a compelling clinical and economic case as trials progress rather than after regulatory approval – often saving millions in post-market study costs and payer authorisation delays.</p><ul><li><a href="/insights/digital-disruption/real-world-data/" target="_self">ICON Real World Data (RWD) Insights</a></li><li>White Paper: <a href="/insights/digital-disruption/real-world-data/maximise-rwe-value/" target="_self">Harnessing technology to maximise RWE value</a></li><li><a href="/insights/value-based-healthcare/global-outcomes-benchmark/" target="_self">ICON and ICHOM unveil the world’s first global patient outcomes benchmarking platform</a></li><li>White Paper: <a href="/insights/digital-disruption/real-world-data/meeting-evidentiary-needs/" target="_self">Meeting evidentiary needs with EHRs</a></li><li><a href="/insights/blog/2018/04/20/accelerating-the-access-and-reimbursement-process/" target="_self">On formulary fast: accelerating the access and reimbursement process</a></li><li><a href="/insights/blog/2018/04/20/reduce-post-market-surveillance-cost/" target="_self">Reduce the cost of post-market surveillance with Real-World Data</a></li></ul></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="069a82f0-2aad-442b-bbb3-417cbda04b12"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/awv6wf6c5t/web/video-thumbnail?crop=yes&w=555&h=339&a=0,0&itok=0gyhCILy 1x, https://icon.widen.net/content/awv6wf6c5t/web/video-thumbnail?crop=yes&w=555&h=339&a=0,0&itok=0gyhCILy 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/awv6wf6c5t/web/video-thumbnail?crop=yes&w=555&h=339&a=0,0&itok=0gyhCILy 1x, 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https://icon.widen.net/content/awv6wf6c5t/web/video-thumbnail?crop=yes&w=555&h=339&a=0,0&itok=0gyhCILy 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/awv6wf6c5t/web/video-thumbnail?crop=yes&w=555&h=339&a=0,0&itok=0gyhCILy 1x, https://icon.widen.net/content/awv6wf6c5t/web/video-thumbnail?crop=yes&w=555&h=339&a=0,0&itok=0gyhCILy 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/awv6wf6c5t/web/video-thumbnail" width="555" height="339" alt="video-thumbnail" title="video-thumbnail" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2></h2> <h3>Design for the patient experience</h3> <div><p>ICON is empowering patients, encouraging compliance, and easing the burden of participating in trials through its <a href="https://www.iconplc.com/solutions/technologies/firecrest/" target="_self">FIRECREST</a> digital platform, backed by extensive research on behavioural decision-making and information technology.</p><ul><li><a href="/news-events/press-releases/voice-assistant-applications/" target="_self">ICON reveals voice-assistant applications for clinical trials</a></li><li><a href="/insights/blog/2018/04/17/leveraging-voice-assistant-technology-in-clinical-trials/" target="_self">Leveraging voice-assistant technology in clinical trials</a></li><li><a href="/insights/blog/2018/04/18/benefits-to-digital-health-ecosystem/" target="_self">How patients and developers benefit in a digital health ecosystem</a></li><li><a href="/insights/blog/2018/05/28/multimedia-approach-to-econsent/" target="_self">Multimedia approach to eConsent instils patient trust in clinical trials</a></li><li><a href="/news-events/press-releases/icon-and-carnegie-mellon/" target="_self">ICON and Carnegie Mellon University collaborate to evaluate patient-centric informed consent processes</a></li></ul></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="1c43d54d-bd1f-4daa-bee8-26b98926b860"> <div class="bg-gray"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h2>Transforming Trials email updates</h2> <h3> </h3> <div> <p>If you would like to receive our Transforming Trials email updates, including the latest on accelerating R&D timelines and minimising costs, adaptive design, CRO partnership strategy, risk-based monitoring, as well as reducing site & investigator burden, <a href="/preferences/" target="_self">click here to go to our preference centre</a>. </p> </div> <a class="btn btn-primary btn-md" href="/preferences" target="_self">Receive Transforming Trials email updates</a> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="bd125fe1-038e-4cf6-915d-6b4b29481a34"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/asqnbbwjct/web/icon-map?crop=yes&w=555&h=339&a=0,0&itok=FVtXPF2A 1x, https://icon.widen.net/content/asqnbbwjct/web/icon-map?crop=yes&w=555&h=339&a=0,0&itok=FVtXPF2A 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/asqnbbwjct/web/icon-map?crop=yes&w=555&h=339&a=0,0&itok=FVtXPF2A 1x, 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767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/asqnbbwjct/web/icon-map?crop=yes&w=555&h=339&a=0,0&itok=FVtXPF2A 1x, https://icon.widen.net/content/asqnbbwjct/web/icon-map?crop=yes&w=555&h=339&a=0,0&itok=FVtXPF2A 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/asqnbbwjct/web/icon-map" width="555" height="339" alt="icon-map" title="icon-map" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2></h2> <h3>Elevate site centricity</h3> <div><p>ICON is transforming the daily experiences of site staff through novel technologies that reduce the burden of participation and a novel centralised site management model, delivered through regional hubs fluent in local languages and customs, that provides a single point of contact from start to finish.</p><div><ul><li><a href="/insights/blog/2018/04/19/technology-enabled-remote-site-model/" target="_self">Technology-enabled remote site model offers one-stop support</a></li><li>White Paper: <a href="http://www2.iconplc.com/whitepaper/oncology_reducingbarriers" target="_blank">Identifying and reducing barriers to oncology clinical research at the site level</a></li><li><a href="https://www.iconplc.com/solutions/technologies/firecrest/" target="_self">Digital solutions to drive site performance</a>   </li><li><a href="/insights/blog/2018/11/05/managing-clinical-trial-training/" target="_self">Managing clinical trial training - Top 5 reasons to use a Learning Management System (LMS)</a></li></ul></div></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="f7c2dd18-0d8a-42c9-a3f0-0a629edd6ac4"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--text-left-picture-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6 order-sm-2"> <div class="text-picture__picture"> <div class="text-picture-link-wrapper"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 1x, https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 1x, https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 1x, https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 1x, https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 1x, https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 1x, https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient?crop=yes&w=555&h=339&a=0,0&itok=v2Efoc8f 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/buxus1mgf2/web/wearable-on-patient" width="555" height="339" alt="wearable-on-patient" title="wearable-on-patient" loading="lazy" /> </picture> </div> </div> </div> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6 col-sm-pull-6"> <div class="text-picture__text"> <h2></h2> <h3>Leverage mobile technology</h3> <div> <p>ICON is investing heavily in security and data validation standards for <a href="/insights/digital-disruption/mHealth-wearables/" target="_self">wearable devices and mobile applications</a>, so that sponsors can take advantage of opportunities to augment clinical and economic outcomes measures, and make studies more convenient and accessible for patients around the world.</p> <ul> <li>White paper: <a href="/insights/digital-disruption/mHealth-wearables/digital-endpoints/" target="_self">Wearables and digital endpoint strategy and validation</a></li> <li>White paper: <a href="/insights/digital-disruption/mHealth-wearables/transforming-medical-device-development-with-mhealth/" target="_self">Transforming medical device development with mHealth</a></li> <li><a href="/insights/digital-disruption/mHealth-wearables/" target="_self">Remote monitoring, wearables and sensors in clinical trials</a></li> <li>Blog: <a href="/insights/blog/2020/08/05/post-pandemic-clinical-tr/" target="_self">Post pandemic cliicla trial strategies</a></li> <li><a href="/insights/blog/2018/04/24/measuring-free-living-activity-in-clinical-trials/" target="_self">Measuring free-living activity in clinical trials</a></li> <li><a href="/news-events/events/webinars/BYOD-eCOA-instrument-validation/" target="_self">Bring your own device (BYOD) eCOA – instrument validation methodology</a></li> </ul> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="a87d8d5a-034e-40ca-b31f-9cc736ed9052"> <div class="bg-gray"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture-wrapper"> <div class="text-picture text-picture--text-only text-left with-separator--top"> <div> <div class="text-picture__text"> <h2>CRO partnership strategies</h2> <h3> </h3> <div> <p>CROs can provide a range of expertise to bring know how and solutions to the highly technical challenges of transforming clinical trials. In the 2018 ICON and Informa industry survey '<a href="/insights/transforming-trials/improving-pharma-research-and-development-efficiency/" target="_self">Improving Pharma R&D Efficiency</a>', executives were asked 'How important will strategic partnerships with CROs be to the success of your clinical trials in the next 5 years?' 83% of respondents stated such relationships would be 'Very Important' or 'Important'. Earlier ICON sponsored research in 2016 on '<strong>Optimising Collaboration Effectiveness in Alliance Partnerships</strong>' conducted by Tufts identified four key themes for optimising collaboration effectiveness:</p> <ul> <li>Evolve the partnership model to 'Design & Execution'</li> <li>Develop a joint innovation agenda</li> <li>Implement an integrated approach to patient centricity</li> <li>Build partnership trust</li> </ul> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="d9cd4565-63bd-438a-b04a-83b328b46aae"> <div class="container-fluid container-fluid--xl text-and-picture-wrapper") }}> <div class="row"> <div class="col-sm"> <div class="text-picture text-left text-picture--picture-left-text-right text-left "> <div class="container-fluid container-fluid--xl"> <div class="row"> <div class="col-sm-6"> <div class="text-picture__picture"> <a class="text-picture-link-wrapper" target="_top" href="/insights/transforming-trials/transforming-the-rd-model"> <div> <div> <picture> <source srcset="https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 1x, https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 2x" media="(min-width: 1400px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 1x, https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 2x" media="(min-width: 1200px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 1x, https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 2x" media="(min-width: 992px) and (max-width: 1199px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 1x, https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 2x" media="(min-width: 768px) and (max-width: 991px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 1x, https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 2x" media="(min-width: 576px) and (max-width: 767px)" width="555" height="339"/> <source srcset="https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 1x, https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg?crop=yes&w=982&h=600&a=757,0&itok=uhhauqjA 2x" media="(max-width: 575px)" width="555" height="339"/> <img src="https://icon.widen.net/content/g9d4qnx7ez/web/r-and-d-model-banner.jpg" width="1920" height="600" alt="r-and-d-model-banner" title="r-and-d-model-banner" loading="lazy" /> </picture> </div> </div> </a> </div> <div class="text-picture__picture-comment"> </div> </div> <div class="text-picture__text-wrapper col-sm-6"> <div class="text-picture__text"> <h2>Transforming medical device development</h2> <h3></h3> <div> <p>To sustain rapid revenue growth, medical device manufacturers are increasingly turning to significant corporate cost saving programmes, often requiring across-the-board cuts between 15 and 30%.</p> <p>Companies are under enormous pressure to introduce products to market faster while also meeting the escalating demands of regulators and payors for post-market research, requiring investment in infrastructure and expertise to maximise reimbursement and keep products on the market.</p> <p>How can manufacturers effectively reconcile these seemingly contradictory challenges?</p> <p>White paper: <a href="/insights/transforming-trials/transforming-the-rd-model/" target="_self">Transforming medical device development: achieving challenging mandates for cost savings and pipeline productivity</a></p> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div class="layout layout--onecol"> <div class="layout__region layout__region--content"> <div id="8ae06c1a-cd22-4bfe-b79e-5a8d170cb49b"> <div class="group bg-green-light content-visibility--auto contain-intrinsic-size--650"> <div class="container-fluid container-fluid--xl"> <h2 class="group__title"> <a 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