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aria-label="Conteúdo" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" title="Índice" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Alternar o índice" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Alternar o índice</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Filodulcina</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ir para um artigo noutra língua. Disponível em 11 línguas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-11" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">11 línguas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-azb mw-list-item"><a href="https://azb.wikipedia.org/wiki/%D9%81%DB%8C%D9%84%E2%80%8C%D9%84%D9%88%D8%AF%D9%88%D9%84%D8%B3%DB%8C%D9%86" title="فیل‌لودولسین — South Azerbaijani" lang="azb" hreflang="azb" data-title="فیل‌لودولسین" data-language-autonym="تۆرکجه" data-language-local-name="South Azerbaijani" class="interlanguage-link-target"><span>تۆرکجه</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Phyllodulcin" title="Phyllodulcin — alemão" lang="de" hreflang="de" data-title="Phyllodulcin" data-language-autonym="Deutsch" data-language-local-name="alemão" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Phyllodulcin" title="Phyllodulcin — inglês" lang="en" hreflang="en" data-title="Phyllodulcin" data-language-autonym="English" data-language-local-name="inglês" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Filodulcina" title="Filodulcina — espanhol" lang="es" hreflang="es" data-title="Filodulcina" data-language-autonym="Español" data-language-local-name="espanhol" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%81%DB%8C%D9%84%E2%80%8C%D9%84%D9%88%D8%AF%D9%88%D9%84%D8%B3%DB%8C%D9%86" title="فیل‌لودولسین — persa" lang="fa" hreflang="fa" data-title="فیل‌لودولسین" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Phyllodulcine" title="Phyllodulcine — francês" lang="fr" hreflang="fr" data-title="Phyllodulcine" data-language-autonym="Français" data-language-local-name="francês" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Fillodulcina" title="Fillodulcina — italiano" lang="it" hreflang="it" data-title="Fillodulcina" data-language-autonym="Italiano" data-language-local-name="italiano" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/%E3%83%95%E3%82%A3%E3%83%AD%E3%82%BA%E3%83%AB%E3%83%81%E3%83%B3" title="フィロズルチン — japonês" lang="ja" hreflang="ja" data-title="フィロズルチン" data-language-autonym="日本語" data-language-local-name="japonês" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Filodulcin" title="Filodulcin — servo-croata" lang="sh" hreflang="sh" data-title="Filodulcin" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="servo-croata" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Filodulcin" title="Filodulcin — sérvio" lang="sr" hreflang="sr" data-title="Filodulcin" data-language-autonym="Српски / srpski" data-language-local-name="sérvio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Phyllodulcin" title="Phyllodulcin — vietnamita" lang="vi" hreflang="vi" data-title="Phyllodulcin" data-language-autonym="Tiếng Việt" data-language-local-name="vietnamita" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q5961163#sitelinks-wikipedia" title="Editar hiperligações interlínguas" class="wbc-editpage">Editar hiperligações</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Espaços nominais"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div 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lang="pt" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r69424239">.mw-parser-output .ib-chembox{border-collapse:collapse;text-align:left}.mw-parser-output .ib-chembox td,.mw-parser-output .ib-chembox th{border:1px solid #a2a9b1;width:40%}.mw-parser-output .ib-chembox td+td{width:60%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .ib-chembox figure:not(.skin-invert-image):not(.skin-invert):not(.bg-transparent){background:var(--background-color-inverted,#f8f9fa)}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .ib-chembox figure:not(.skin-invert-image):not(.skin-invert):not(.bg-transparent){background:var(--background-color-inverted,#f8f9fa)}}</style> <table class="infobox ib-chembox" style="width: 300px; float: right; clear: right; margin: 0 0 1em 1em; border-collapse: collapse;"> <tbody><tr> <th style="background: #F8EABA; text-align: center;" colspan="2">Filodulcina<br /><small><i>phyllodulcin</i></small><br /><small><a href="/wiki/Wikip%C3%A9dia:Aviso_m%C3%A9dico" title="Wikipédia:Aviso médico">Alerta sobre risco à saúde</a></small> </th></tr> <tr> <td align="center" colspan="2" bgcolor="#ffffff"><span typeof="mw:File"><a href="/wiki/Ficheiro:Phyllodulcin.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Phyllodulcin.svg/200px-Phyllodulcin.svg.png" decoding="async" width="200" height="157" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/04/Phyllodulcin.svg/300px-Phyllodulcin.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/04/Phyllodulcin.svg/400px-Phyllodulcin.svg.png 2x" data-file-width="580" data-file-height="455" /></a></span> </td></tr> <tr> <td><a href="/wiki/Nomenclatura_IUPAC" title="Nomenclatura IUPAC">Nome IUPAC</a> </td> <td>(3R)-8-hidroxi-3-(3-hidroxi-4-metoxifenil)-3,4-dihidroisocromen-1-ona </td></tr> <tr> <td>Outros nomes </td> <td><a href="/wiki/Praeruptorin" class="mw-redirect" title="Praeruptorin">Praeruptorin</a> </td></tr> <tr> <th style="background: #F8EABA; text-align: center;" colspan="2">Identificadores </th></tr> <tr> <td bgcolor=""><a href="/wiki/Registro_CAS" class="mw-redirect" title="Registro CAS">Número CAS</a> </td> <td bgcolor=""><span class="reflink plainlinksneverexpand"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=21499-23-0">21499-23-0</a></span> </td></tr> <tr> <td><a href="/wiki/PubChem" title="PubChem">PubChem</a> </td> <td><span class="reflink plainlinksneverexpand"><a rel="nofollow" class="external text" href="http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=146694">146694</a></span> </td></tr> <tr> <td><a href="/wiki/SMILES" title="SMILES">SMILES</a> </td> <td><small><tt><div class="NavFrame collapsed" style="border: none; padding: 0;"> <div class="NavHead" style="font-size: 105%; background: transparent; text-align: left;"> </div> <ul class="NavContent" style="list-style: none none; margin-left: 0; text-align: left; font-size: 105%; margin-top: 0; margin-bottom: 0; line-height: inherit;"><li style="line-height: inherit; margin: 0">COC1=C(C=C(C=C1)C2CC3=C(C(=CC=C3)O)C(=O)O2)O</li></ul> </div></tt></small> </td></tr> <tr> <th style="background: #F8EABA; text-align: center;" colspan="2">Propriedades </th></tr> <tr> <td><a href="/wiki/F%C3%B3rmula_qu%C3%ADmica" title="Fórmula química">Fórmula molecular</a> </td> <td>C<sub>16</sub>H<sub>14</sub>O<sub>5</sub> </td></tr> <tr> <td><a href="/wiki/Massa_molar" title="Massa molar">Massa molar</a> </td> <td>286.27 g/mol </td></tr> <tr> <th style="background: #F8EABA; text-align: center;" colspan="2"><a class="mw-selflink selflink">Página de dados suplementares</a> </th></tr> <tr> <td><a class="mw-selflink-fragment" href="#Estrutura_e_propriedades">Estrutura e propriedades</a> </td> <td><a href="/wiki/%C3%8Dndice_de_refrac%C3%A7%C3%A3o" class="mw-redirect" title="Índice de refracção"><i>n</i></a>, <a href="/wiki/Constante_diel%C3%A9ctrica" class="mw-redirect" title="Constante dieléctrica">ε<sub>r</sub></a>, etc. </td></tr> <tr> <td><a class="mw-selflink-fragment" href="#Propriedades_termodinâmicas">Dados termodinâmicos</a> </td> <td>Phase behaviour<br />Solid, liquid, gas </td></tr> <tr> <td><a class="mw-selflink-fragment" href="#Dados_espectrais">Dados espectrais</a> </td> <td><a href="/wiki/Espectroscopia_UV/vis%C3%ADvel" title="Espectroscopia UV/visível">UV</a>, <a href="/wiki/Espectroscopia_de_infravermelho" title="Espectroscopia de infravermelho">IV</a>, <a href="/wiki/Espectroscopia_de_resson%C3%A2ncia_magn%C3%A9tica_nuclear" class="mw-redirect" title="Espectroscopia de ressonância magnética nuclear">RMN</a>, <a href="/wiki/Espectroscopia_de_massa" class="mw-redirect" title="Espectroscopia de massa">EM</a> </td></tr> <tr> <td style="background: #F8EABA; text-align: center;" colspan="2"><small><b>Exceto onde denotado, os dados referem-se a<br /> materiais sob <a href="/wiki/Condi%C3%A7%C3%B5es_normais_de_temperatura_e_press%C3%A3o" title="Condições normais de temperatura e pressão">condições normais de temperatura e pressão</a></b><br /><b><a href="/wiki/Wikip%C3%A9dia:Informa%C3%A7%C3%A3o_nas_infocaixas_de_qu%C3%ADmica" title="Wikipédia:Informação nas infocaixas de química">Referências e avisos gerais sobre esta caixa</a>.</b><br /><b><a href="/wiki/Wikip%C3%A9dia:Aviso_m%C3%A9dico" title="Wikipédia:Aviso médico">Alerta sobre risco à saúde</a>.</b> </small> </td></tr> </tbody></table> <p><b>Filodulcina</b>, conhecida também pela designação <i>phyllodulcin</i>, é uma <a href="/wiki/Isocumarina" title="Isocumarina">dihidroisocumarina</a> que ocorre naturalmente em algumas <a href="/wiki/Esp%C3%A9cie" title="Espécie">espécies</a> do <a href="/wiki/G%C3%A9nero_(biologia)" title="Género (biologia)">género</a> <i><a href="/wiki/Hydrangea" title="Hydrangea">Hydrangea</a></i>, nomeadamente em <i><a href="/wiki/Hydrangea_macrophylla" title="Hydrangea macrophylla">Hydrangea macrophylla</a></i><sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span>[</span>1<span>]</span></a></sup> e <i><a href="/w/index.php?title=Hydrangea_serrata&action=edit&redlink=1" class="new" title="Hydrangea serrata (página não existe)">Hydrangea serrata</a></i>.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span>[</span>2<span>]</span></a></sup> O composto apresenta forte actividade <a href="/wiki/Edulcorante" class="mw-redirect" title="Edulcorante">edulcorante</a>, sendo 400-800 vezes mais adoçante que o <a href="/wiki/Sacarose" title="Sacarose">açúcar de mesa</a>.<sup id="cite_ref-Tomasik-2003_3-0" class="reference"><a href="#cite_note-Tomasik-2003-3"><span>[</span>3<span>]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Ver_também"><span id="Ver_tamb.C3.A9m"></span>Ver também</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Filodulcina&veaction=edit&section=1" title="Editar secção: Ver também" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Filodulcina&action=edit&section=1" title="Editar código-fonte da secção: Ver também"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Amacha" title="Amacha">Amacha</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Referências"><span id="Refer.C3.AAncias"></span>Referências</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Filodulcina&veaction=edit&section=2" title="Editar secção: Referências" class="mw-editsection-visualeditor"><span>editar</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=Filodulcina&action=edit&section=2" title="Editar código-fonte da secção: Referências"><span>editar código-fonte</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist" style="list-style-type: decimal;"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text">Effects of phyllodulcin, <a href="/wiki/Hydrangenol" class="mw-redirect" title="Hydrangenol">hydrangenol</a>, and their 8-O-glucosides, and <a href="/w/index.php?title=Thunberginol_A&action=edit&redlink=1" class="new" title="Thunberginol A (página não existe)">Thunberginols A</a> and <a href="/w/index.php?title=Thunberginol_F&action=edit&redlink=1" class="new" title="Thunberginol F (página não existe)">F</a> from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Matsuda H., Shimoda H., Yamahara J. and Yoshikawa M., Biological & pharmaceutical bulletin, 1999, vol. 22, no8, pp. 870-872, <a href="/w/index.php?title=Institut_de_l%27information_scientifique_et_technique&action=edit&redlink=1" class="new" title="Institut de l'information scientifique et technique (página não existe)">INIST</a>:<a rel="nofollow" class="external text" href="http://cat.inist.fr/?aModele=afficheN&cpsidt=1959604">1959604</a> </span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text">Accumulation of phyllodulcin in sweet-leaf plants of Hydrangea serrata and its neutrality in the defence against a specialist leafmining herbivore. Mami Ujihara, Masateru Shinozaki and Makoto Kato, Researches on population ecology, Volume 37, Number 2, pp. 249-257, <a href="/wiki/Digital_object_identifier" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1007%2FBF02515827">10.1007/BF02515827</a></span> </li> <li id="cite_note-Tomasik-2003-3"><span class="mw-cite-backlink"><a href="#cite_ref-Tomasik-2003_3-0">↑</a></span> <span class="reference-text">Chemical and Functional Properties of Food Saccharides. P. Tomasik, CRC Press, Boca Raton, 2003 , isbn : 978-0-8493-1486-5</span> </li> </ol></div></div> <p><a href="/w/index.php?title=Predefini%C3%A7%C3%A3o:Isocoumarinas&action=edit&redlink=1" class="new" title="Predefinição:Isocoumarinas (página não existe)">Predefinição:Isocoumarinas</a> </p>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?useformat=desktop&type=1x1&usesul3=0" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Obtida de "<a dir="ltr" href="https://pt.wikipedia.org/w/index.php?title=Filodulcina&oldid=62152052">https://pt.wikipedia.org/w/index.php?title=Filodulcina&oldid=62152052</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Especial:Categorias" title="Especial:Categorias">Categorias</a>: <ul><li><a href="/wiki/Categoria:Cumarinas" title="Categoria:Cumarinas">Cumarinas</a></li><li><a href="/wiki/Categoria:Ado%C3%A7antes" title="Categoria:Adoçantes">Adoçantes</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> Esta página foi editada pela última vez às 21h21min de 30 de setembro de 2021.</li> <li id="footer-info-copyright">Este texto é disponibilizado nos termos da licença <a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.pt">Atribuição-CompartilhaIgual 4.0 Internacional (CC BY-SA 4.0) da Creative Commons</a>; pode estar sujeito a condições adicionais. 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