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Search results for: guided discovery
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text-center" style="font-size:1.6rem;">Search results for: guided discovery</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1298</span> Guided Energy Theory of a Particle: Answered Questions Arise from Quantum Foundation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Desmond%20Agbolade%20Ademola">Desmond Agbolade Ademola</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This work aimed to introduce a theory, called Guided Energy Theory of a particle that answered questions that arise from quantum foundation, quantum mechanics theory, and interpretation such as: what is nature of wavefunction? Is mathematical formalism of wavefunction correct? Does wavefunction collapse during measurement? Do quantum physical entanglement and many world interpretations really exist? In addition, is there uncertainty in the physical reality of our nature as being concluded in the Quantum theory? We have been able to show by the fundamental analysis presented in this work that the way quantum mechanics theory, and interpretation describes nature is not correlated with physical reality. Because, we discovered amongst others that, (1) Guided energy theory of a particle fundamentally provides complete physical observable series of quantized measurement of a particle momentum, force, energy e.t.c. in a given distance and time.In contrast, quantum mechanics wavefunction describes that nature has inherited probabilistic and indeterministic physical quantities, resulting in unobservable physical quantities that lead to many worldinterpretation.(2) Guided energy theory of a particle fundamentally predicts that it is mathematically possible to determine precise quantized measurementof position and momentum of a particle simultaneously. Because, there is no uncertainty in nature; nature however naturally guides itself against uncertainty. Contrary to the conclusion in quantum mechanics theory that, it is mathematically impossible to determine the position and the momentum of a particle simultaneously. Furthermore, we have been able to show by this theory that, it is mathematically possible to determine quantized measurement of force acting on a particle simultaneously, which is not possible on the premise of quantum mechanics theory. (3) It is evidently shown by our theory that, guided energy does not collapse, only describes the lopsided nature of a particle behavior in motion. This pretty offers us insight on gradual process of engagement - convergence and disengagement – divergence of guided energy holders which further highlight the picture how wave – like behavior return to particle-like behavior and how particle – like behavior return to wave – like behavior respectively. This further proves that the particles’ behavior in motion is oscillatory in nature. The mathematical formalism of Guided energy theory shows that nature is certainty whereas the mathematical formalism of Quantum mechanics theory shows that nature is absolutely probabilistics. In addition, the nature of wavefunction is the guided energy of the wave. In conclusion, the fundamental mathematical formalism of Quantum mechanics theory is wrong. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=momentum" title="momentum">momentum</a>, <a href="https://publications.waset.org/abstracts/search?q=physical%20entanglement" title=" physical entanglement"> physical entanglement</a>, <a href="https://publications.waset.org/abstracts/search?q=wavefunction" title=" wavefunction"> wavefunction</a>, <a href="https://publications.waset.org/abstracts/search?q=uncertainty" title=" uncertainty"> uncertainty</a> </p> <a href="https://publications.waset.org/abstracts/72416/guided-energy-theory-of-a-particle-answered-questions-arise-from-quantum-foundation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/72416.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">295</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1297</span> Computed Tomography Guided Bone Biopsies: Experience at an Australian Metropolitan Hospital</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=K.%20Hinde">K. Hinde</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Bookun"> R. Bookun</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Tran"> P. Tran</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Percutaneous CT guided biopsies provide a fast, minimally invasive, cost effective and safe method for obtaining tissue for histopathology and culture. Standards for diagnostic yield vary depending on whether the tissue is being obtained for histopathology or culture. We present a retrospective audit from Western Health in Melbourne Australia over a 12-month period which aimed to determine the diagnostic yield, technical success and complication rate for CT guided bone biopsies and identify factors affecting these results. The digital imaging storage program (Synapse Picture Archiving and Communication System – Fujifilm Australia) was analysed with key word searches from October 2015 to October 2016. Nineteen CT guided bone biopsies were performed during this time. The most common referring unit was oncology, work up imaging included CT, MRI, bone scan and PET scan. The complication rate was 0%, overall diagnostic yield was 74% with a technical success of 95%. When performing biopsies for histologic analysis diagnostic yield was 85% and when performing biopsies for bacterial culture diagnostic yield was 60%. There was no significant relationship identified between size of lesion, distance of lesion to skin, lesion appearance on CT, the number of samples taken or gauge of needle to diagnostic yield or technical success. CT guided bone biopsy at Western Health meets the standard reported at other major clinical centres for technical success and safety. It is a useful investigation in identification of primary malignancy in distal bone metastases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bone%20biopsy" title="bone biopsy">bone biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title=" computed tomography"> computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=core%20biopsy" title=" core biopsy"> core biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=histopathology" title=" histopathology"> histopathology</a> </p> <a href="https://publications.waset.org/abstracts/77030/computed-tomography-guided-bone-biopsies-experience-at-an-australian-metropolitan-hospital" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/77030.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">200</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1296</span> Knowledge-Driven Decision Support System Based on Knowledge Warehouse and Data Mining by Improving Apriori Algorithm with Fuzzy Logic</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pejman%20Hosseinioun">Pejman Hosseinioun</a>, <a href="https://publications.waset.org/abstracts/search?q=Hasan%20Shakeri"> Hasan Shakeri</a>, <a href="https://publications.waset.org/abstracts/search?q=Ghasem%20Ghorbanirostam"> Ghasem Ghorbanirostam</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In recent years, we have seen an increasing importance of research and study on knowledge source, decision support systems, data mining and procedure of knowledge discovery in data bases and it is considered that each of these aspects affects the others. In this article, we have merged information source and knowledge source to suggest a knowledge based system within limits of management based on storing and restoring of knowledge to manage information and improve decision making and resources. In this article, we have used method of data mining and Apriori algorithm in procedure of knowledge discovery one of the problems of Apriori algorithm is that, a user should specify the minimum threshold for supporting the regularity. Imagine that a user wants to apply Apriori algorithm for a database with millions of transactions. Definitely, the user does not have necessary knowledge of all existing transactions in that database, and therefore cannot specify a suitable threshold. Our purpose in this article is to improve Apriori algorithm. To achieve our goal, we tried using fuzzy logic to put data in different clusters before applying the Apriori algorithm for existing data in the database and we also try to suggest the most suitable threshold to the user automatically. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=decision%20support%20system" title="decision support system">decision support system</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20mining" title=" data mining"> data mining</a>, <a href="https://publications.waset.org/abstracts/search?q=knowledge%20discovery" title=" knowledge discovery"> knowledge discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20discovery" title=" data discovery"> data discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=fuzzy%20logic" title=" fuzzy logic"> fuzzy logic</a> </p> <a href="https://publications.waset.org/abstracts/48155/knowledge-driven-decision-support-system-based-on-knowledge-warehouse-and-data-mining-by-improving-apriori-algorithm-with-fuzzy-logic" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/48155.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">335</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1295</span> Zika Virus NS5 Protein Potential Inhibitors: An Enhanced in silico Approach in Drug Discovery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Pritika%20Ramharack">Pritika Ramharack</a>, <a href="https://publications.waset.org/abstracts/search?q=Mahmoud%20E.%20S.%20Soliman"> Mahmoud E. S. Soliman</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The re-emerging Zika virus is an arthropod-borne virus that has been described to have explosive potential as a worldwide pandemic. The initial transmission of the virus was through a mosquito vector, however, evolving modes of transmission has allowed the spread of the disease over continents. The virus already been linked to irreversible chronic central nervous system (CNS) conditions. The concerns of the scientific and clinical community are the consequences of Zika viral mutations, thus suggesting the urgent need for viral inhibitors. There have been large strides in vaccine development against the virus but there are still no FDA-approved drugs available. Rapid rational drug design and discovery research is fundamental in the production of potent inhibitors against the virus that will not just mask the virus, but destroy it completely. In silico drug design allows for this prompt screening of potential leads, thus decreasing the consumption of precious time and resources. This study demonstrates an optimized and proven screening technique in the discovery of two potential small molecule inhibitors of Zika virus Methyltransferase and RNA-dependent RNA polymerase. This in silico “per-residue energy decomposition pharmacophore” virtual screening approach will be critical in aiding scientists in the discovery of not only effective inhibitors of Zika viral targets, but also a wide range of anti-viral agents. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=NS5%20protein%20inhibitors" title="NS5 protein inhibitors">NS5 protein inhibitors</a>, <a href="https://publications.waset.org/abstracts/search?q=per-residue%20decomposition" title=" per-residue decomposition"> per-residue decomposition</a>, <a href="https://publications.waset.org/abstracts/search?q=pharmacophore%20model" title=" pharmacophore model"> pharmacophore model</a>, <a href="https://publications.waset.org/abstracts/search?q=virtual%20screening" title=" virtual screening"> virtual screening</a>, <a href="https://publications.waset.org/abstracts/search?q=Zika%20virus" title=" Zika virus"> Zika virus</a> </p> <a href="https://publications.waset.org/abstracts/59456/zika-virus-ns5-protein-potential-inhibitors-an-enhanced-in-silico-approach-in-drug-discovery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/59456.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">227</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1294</span> Effect of Three Instructional Strategies on Pre-service Teachers’ Learning Outcomes in Practical Chemistry in Niger State, Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Akpokiere%20Ugbede%20Roseline">Akpokiere Ugbede Roseline</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Chemistry is an activity oriented subject in which many students achievement over the years are not encouraging. Among the reasons found to be responsible for student’s poor performance in chemistry are ineffective teaching strategies. This study, therefore, sought to determine the effect of guided inquiry, guided inquiry with demonstration, and demonstration with conventional approach on pre-service teachers’ cognitive attainment and practical skills acquisition on stoichiometry and chemical reactions in practical chemistry, Two research questions and hypotheses were each answered and tested respectively. The study was a quasi-experimental research involving 50 students in each of the experimental groups and 50 students in the control group. Out of the five instruments used for the study, three were on stimulus and two on response (Test of Cognitive Attainment and Test of Practical Skills in Chemistry) instruments administered, and dataobtained were analyzed with t-test and Analysis of Variance. Findings revealed, among others, that there was a significant effect of treatments on students' cognitive attainment and on practical skills acquisition. Students exposed to guided inquiry (with/without demonstration) strategies achieved better than those exposed to demonstration with conventional strategy. It is therefore recommended, among others, that Lecturers in Colleges of Education should utilize the guided inquiry strategy for teaching concepts in chemistry. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=instructional%20strategy" title="instructional strategy">instructional strategy</a>, <a href="https://publications.waset.org/abstracts/search?q=practical%20chemistry" title=" practical chemistry"> practical chemistry</a>, <a href="https://publications.waset.org/abstracts/search?q=learning%20outcomes" title=" learning outcomes"> learning outcomes</a>, <a href="https://publications.waset.org/abstracts/search?q=pre-service%20teachers" title=" pre-service teachers"> pre-service teachers</a> </p> <a href="https://publications.waset.org/abstracts/150981/effect-of-three-instructional-strategies-on-pre-service-teachers-learning-outcomes-in-practical-chemistry-in-niger-state-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/150981.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">103</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1293</span> Modeling Optimal Lipophilicity and Drug Performance in Ligand-Receptor Interactions: A Machine Learning Approach to Drug Discovery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jay%20Ananth">Jay Ananth</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The drug discovery process currently requires numerous years of clinical testing as well as money just for a single drug to earn FDA approval. For drugs that even make it this far in the process, there is a very slim chance of receiving FDA approval, resulting in detrimental hurdles to drug accessibility. To minimize these inefficiencies, numerous studies have implemented computational methods, although few computational investigations have focused on a crucial feature of drugs: lipophilicity. Lipophilicity is a physical attribute of a compound that measures its solubility in lipids and is a determinant of drug efficacy. This project leverages Artificial Intelligence to predict the impact of a drug’s lipophilicity on its performance by accounting for factors such as binding affinity and toxicity. The model predicted lipophilicity and binding affinity in the validation set with very high R² scores of 0.921 and 0.788, respectively, while also being applicable to a variety of target receptors. The results expressed a strong positive correlation between lipophilicity and both binding affinity and toxicity. The model helps in both drug development and discovery, providing every pharmaceutical company with recommended lipophilicity levels for drug candidates as well as a rapid assessment of early-stage drugs prior to any testing, eliminating significant amounts of time and resources currently restricting drug accessibility. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=drug%20discovery" title="drug discovery">drug discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=lipophilicity" title=" lipophilicity"> lipophilicity</a>, <a href="https://publications.waset.org/abstracts/search?q=ligand-receptor%20interactions" title=" ligand-receptor interactions"> ligand-receptor interactions</a>, <a href="https://publications.waset.org/abstracts/search?q=machine%20learning" title=" machine learning"> machine learning</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20development" title=" drug development"> drug development</a> </p> <a href="https://publications.waset.org/abstracts/163127/modeling-optimal-lipophilicity-and-drug-performance-in-ligand-receptor-interactions-a-machine-learning-approach-to-drug-discovery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/163127.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">111</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1292</span> Characterization of Natural Polymers for Guided Bone Regeneration Applications</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Benedetta%20Isella">Benedetta Isella</a>, <a href="https://publications.waset.org/abstracts/search?q=Aleksander%20Drinic"> Aleksander Drinic</a>, <a href="https://publications.waset.org/abstracts/search?q=Alissa%20Heim"> Alissa Heim</a>, <a href="https://publications.waset.org/abstracts/search?q=Phillip%20Czichowski"> Phillip Czichowski</a>, <a href="https://publications.waset.org/abstracts/search?q=Lisa%20Lauts"> Lisa Lauts</a>, <a href="https://publications.waset.org/abstracts/search?q=Hans%20Leemhuis"> Hans Leemhuis</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Membranes for guided bone regeneration are essential to perform a barrier function between the soft and the regenerating bone tissue. Bioabsorbable membranes are desirable in this field as they do not require a secondary surgery for removal, decreasing patient surgical risk. Collagen was the first bioabsorbable alternative introduced on the market, but its degradation time may be too fast to guarantee bone regeneration, and optimisation is needed. Silk fibroin, being biocompatible, slowly bioabsorbable, and processable into different scaffold types, could be a promising alternative. Objectives: The objective is to compare the general performance of a silk fibroin membrane for guided bone regeneration to current collagen alternatives developing suitable standardized tests for the mechanical and morphological characterization. Methods: Silk fibroin and collagen-based membranes were compared from the morphological and chemical perspective, with techniques such as SEM imaging and from the mechanical point of view with techniques such as tensile and suture retention strength (SRS) tests. Results: Silk fibroin revealed a high degree of reproducibility in surface density. The SRS of silk fibroin (0.76 ± 0.04 N), although lower than collagen, was still comparable to native tissues such as the internal mammary artery (0.56 N), and the same can be extended to general mechanical behaviour in tensile tests. The SRS could be increased by an increase in thickness. Conclusion: Silk fibroin is a promising material in the field of guided bone regeneration, covering the interesting position of not being considered a product containing cells or tissues of animal origin from the regulatory perspective and having longer degradation times with respect to collagen. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=guided%20bone%20regeneration" title="guided bone regeneration">guided bone regeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=mechanical%20characterization" title=" mechanical characterization"> mechanical characterization</a>, <a href="https://publications.waset.org/abstracts/search?q=membrane" title=" membrane"> membrane</a>, <a href="https://publications.waset.org/abstracts/search?q=silk%20fibroin" title=" silk fibroin"> silk fibroin</a> </p> <a href="https://publications.waset.org/abstracts/187400/characterization-of-natural-polymers-for-guided-bone-regeneration-applications" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/187400.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">42</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1291</span> An Exploration of the Integration of Guided Play With Explicit Instruction in Early Childhood Mathematics</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Anne%20Tan">Anne Tan</a>, <a href="https://publications.waset.org/abstracts/search?q=Kok-Sing%20Tang"> Kok-Sing Tang</a>, <a href="https://publications.waset.org/abstracts/search?q=Audrey%20Cooke"> Audrey Cooke</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Play has always been a prominent pedagogy in early childhood. However, there is growing evidence of success in students’ learning using explicit instruction, especially in literacy in the early years. There is also limited research using explicit instruction in early childhood mathematics, and play is usually prominently mentioned. This proposed research aims to investigate the possibilities and benefits of integrating guided play with explicit instruction in early childhood mathematics education. While play has traditionally been a prominent pedagogy in early childhood, there is growing evidence of success in student learning through explicit instruction, particularly in literacy. However, limited research exists on the integration of explicit instruction in early childhood mathematics, where play remains prominently mentioned. This study utilises a multiple case study methodology to gather data and provide immediate opportunities for curriculum improvement. The research will commence with semi-structured interviews to gain insights into educators' background knowledge. Highly structured observations will be conducted to record the frequency and manner in which guided play is integrated with specific elements of explicit instruction during mathematics teaching in early childhood. To enhance the observations, video recordings will be made using cameras with video settings and Microsoft Teams meeting recordings. In addition to interviews and observations, educators will maintain journals and use the Microsoft Teams platform for self-reflection on the integration of guided play and explicit instruction in their classroom practices and experiences. The study participants will include educators with early childhood degrees and students in years one and two. The primary goal of this research is to inform the benefits of integrating two high-impact pedagogies, guided play, and explicit instruction, for enhancing student learning outcomes in mathematics education. By exploring the integration of these pedagogical approaches, this study aims to contribute to the development of effective instructional strategies in early childhood mathematics education. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=early%20childhood" title="early childhood">early childhood</a>, <a href="https://publications.waset.org/abstracts/search?q=early%20childhood%20mathematics" title=" early childhood mathematics"> early childhood mathematics</a>, <a href="https://publications.waset.org/abstracts/search?q=early%20childhood%20numbers" title=" early childhood numbers"> early childhood numbers</a>, <a href="https://publications.waset.org/abstracts/search?q=guided%20play" title=" guided play"> guided play</a>, <a href="https://publications.waset.org/abstracts/search?q=play-based%20learning" title=" play-based learning"> play-based learning</a>, <a href="https://publications.waset.org/abstracts/search?q=explicit%20instruction" title=" explicit instruction"> explicit instruction</a> </p> <a href="https://publications.waset.org/abstracts/174140/an-exploration-of-the-integration-of-guided-play-with-explicit-instruction-in-early-childhood-mathematics" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174140.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">64</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1290</span> The Usefulness and Limitations of Manual Aspiration Immediately after Pneumothorax Complicating Percutaneous CT Guided Lung Biopsies: A Retrospective 9-Year Review from a Large Tertiary Centre</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Niall%20Fennessy">Niall Fennessy</a>, <a href="https://publications.waset.org/abstracts/search?q=Charlotte%20Yin"> Charlotte Yin</a>, <a href="https://publications.waset.org/abstracts/search?q=Vineet%20Gorolay"> Vineet Gorolay</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Chan"> Michael Chan</a>, <a href="https://publications.waset.org/abstracts/search?q=Ilias%20Drivas"> Ilias Drivas</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: The aim of this study was to evaluate the effect of manual aspiration of air from the pleural cavity in mitigating the need for chest drain placement after a CT-guided lung biopsy. Method: This is a single institution retrospective review of CT-guided lung biopsies performed on 799 patients between September 2013 and May 2021 in a major tertiary hospital. Percutaneous manual aspiration of air was performed in 104/306 patients (34%) with pneumothoraxes as a preventative measure. Simple and multivariate analysis was performed to identify independent risk factors (modifiable and nonmodifiable) for the success of manual aspiration in mitigating the need for chest drain insertion. Results: The overall incidence of pneumothorax was 37% (295/799). Chest drains were inserted for 81/295 (27%) of the pneumothoraxes, representing 81/799 (10%) of all CT-guided lung biopsies. Of patients with pneumothoraces, 104 (36%) underwent percutaneous aspiration via either the coaxial guide needle or an 18 or 20G intravenous catheter attached to a three-way stopcock and syringe. Amongst this group, 13 patients (13%) subsequently required chest drain insertion. The success of percutaneous aspiration in avoiding subsequent pleural drain insertion decreased with aspiration volume >500mL, radial pneumothorax depth >3cm, increased subpleural depth of the lesion, and the presence of background emphysema. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title="computed tomography">computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=lung%20biopsy" title=" lung biopsy"> lung biopsy</a>, <a href="https://publications.waset.org/abstracts/search?q=pneumothorax" title=" pneumothorax"> pneumothorax</a>, <a href="https://publications.waset.org/abstracts/search?q=manual%20aspiration" title=" manual aspiration"> manual aspiration</a>, <a href="https://publications.waset.org/abstracts/search?q=chest%20drainage" title=" chest drainage"> chest drainage</a> </p> <a href="https://publications.waset.org/abstracts/140907/the-usefulness-and-limitations-of-manual-aspiration-immediately-after-pneumothorax-complicating-percutaneous-ct-guided-lung-biopsies-a-retrospective-9-year-review-from-a-large-tertiary-centre" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140907.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">175</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1289</span> Simplifying Writing Composition to Assist Students in Rural Areas: An Experimental Study for the Comparison of Guided and Unguided Instruction</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Neha%20Toppo">Neha Toppo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Method and strategies of teaching instruction highly influence learning of students. In second language teaching, number of ways and methods has been suggested by different scholars and researchers through times. The present article deals with the role of teaching instruction in developing compositional ability of students in writing. It focuses on the secondary level students of rural areas, whose exposure to English language is limited and they face challenges even in simple compositions. The students till high school suffer with their disability in writing formal letter, application, essay, paragraph etc. They face problem in note making, writing answers in examination using their own words and depend fully on rote learning. It becomes difficult for them to give language to their own ideas. Teaching writing composition deserves special attention as writing is an integral part of language learning and students at this level are expected to have sound compositional ability for it is useful in numerous domains. Effective method of instruction could help students to learn expression of self, correct selection of vocabulary and grammar, contextual writing, composition of formal and informal writing. It is not limited to school but continues to be important in various other fields outside the school such as in newspaper and magazine, official work, legislative work, material writing, academic writing, personal writing, etc. The study is based on the experimental method, which hypothesize that guided instruction will be more effective in teaching writing compositions than usual instruction in which students are left to compose by their own without any help. In the test, students of one section are asked to write an essay on the given topic without guidance and another section are asked to write the same but with the assistance of guided instruction in which students have been provided with a few vocabulary and sentence structure. This process is repeated in few more schools to get generalize data. The study shows the difference on students’ performance using both the instructions; guided and unguided. The conclusion of the study is followed by the finding that writing skill of the students is quite poor but with the help of guided instruction they perform better. The students are in need of better teaching instruction to develop their writing skills. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=composition" title="composition">composition</a>, <a href="https://publications.waset.org/abstracts/search?q=essay" title=" essay"> essay</a>, <a href="https://publications.waset.org/abstracts/search?q=guided%20instruction" title=" guided instruction"> guided instruction</a>, <a href="https://publications.waset.org/abstracts/search?q=writing%20skill" title=" writing skill"> writing skill</a> </p> <a href="https://publications.waset.org/abstracts/60632/simplifying-writing-composition-to-assist-students-in-rural-areas-an-experimental-study-for-the-comparison-of-guided-and-unguided-instruction" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/60632.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">279</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1288</span> Application of Causal Inference and Discovery in Curriculum Evaluation and Continuous Improvement</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lunliang%20Zhong">Lunliang Zhong</a>, <a href="https://publications.waset.org/abstracts/search?q=Bin%20Duan"> Bin Duan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The undergraduate graduation project is a vital part of the higher education curriculum, crucial for engineering accreditation. Current evaluations often summarize data without identifying underlying issues. This study applies the Peter-Clark algorithm to analyze causal relationships within the graduation project data of an Electronics and Information Engineering program, creating a causal model. Structural equation modeling confirmed the model's validity. The analysis reveals key teaching stages affecting project success, uncovering problems in the process. Introducing causal discovery and inference into project evaluation helps identify issues and propose targeted improvement measures. The effectiveness of these measures is validated by comparing the learning outcomes of two student cohorts, stratified by confounding factors, leading to improved teaching quality. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=causal%20discovery" title="causal discovery">causal discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=causal%20inference" title=" causal inference"> causal inference</a>, <a href="https://publications.waset.org/abstracts/search?q=continuous%20improvement" title=" continuous improvement"> continuous improvement</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter-Clark%20algorithm" title=" Peter-Clark algorithm"> Peter-Clark algorithm</a>, <a href="https://publications.waset.org/abstracts/search?q=structural%20equation%20modeling" title=" structural equation modeling"> structural equation modeling</a> </p> <a href="https://publications.waset.org/abstracts/191014/application-of-causal-inference-and-discovery-in-curriculum-evaluation-and-continuous-improvement" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/191014.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">18</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1287</span> Ultrasound Guided Treatment of Carpal Tunnel Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kazem%20Shakouri">Kazem Shakouri</a>, <a href="https://publications.waset.org/abstracts/search?q=Alireza%20Pishgahi"> Alireza Pishgahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Homayoun%20Sadeghi-bBazargani"> Homayoun Sadeghi-bBazargani</a>, <a href="https://publications.waset.org/abstracts/search?q=Shahla%20Dareshiri"> Shahla Dareshiri </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Carpal Tunnel Syndrome has numerous nonsurgical treatments including splint, physical therapy and corticosteroid injections. Aim: The purpose of this study was to evaluate the effectiveness of an ultrasound guided treatment procedure, for individuals with severe carpal tunnel syndrome. Materials and Method: 20 patients with an electrodiagnostic evidence of severe carpal tunnel syndrome were treated by an office-based ultrasound guided procedure (combination of percutaneous needle release of carpal tunnel and corticosteroid injection). Electrodiagnostic (nerve conduction study), clinical (Boston Carpal Tunnel Questionnaire, grip strength) and ultrasonic (median nerve and carpal tunnel cross-sectional area) measurements were recorded at baseline and one month after intervention. Results: Our preliminary data analysis showed that in one month follow up, patients had a significantly smaller cross-sectional area of the median nerve compared to pretreatment values (mean difference 0.06; 95%CI: 0.02-0.1; p < 0.001). In addition, patients had significantly less functional impairment (mean difference 35; 95% CI:28.7-43.4 ; p < 0.001), and an improved hand grip strength in one month follow up (mean difference 5.4; 95%CI: 3.1-7.8; p < 0.001;). There were no significant complications. Conclusion: Patients with severe carpal tunnel syndrome, who are candidates for surgical intervention, can consider office-based ultrasound guided needle release of carpal tunnel as an alternative safe treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Carpal%20Tunnel%20Syndrome" title="Carpal Tunnel Syndrome">Carpal Tunnel Syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=needle%20release" title=" needle release"> needle release</a>, <a href="https://publications.waset.org/abstracts/search?q=pain" title=" pain"> pain</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrasound" title=" ultrasound"> ultrasound</a> </p> <a href="https://publications.waset.org/abstracts/74847/ultrasound-guided-treatment-of-carpal-tunnel-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74847.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">247</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1286</span> Co-Registered Identification and Treatment of Skin Tumor with Optical Coherence Tomography-Guided Laser Therapy</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bo-Huei%20Huang">Bo-Huei Huang</a>, <a href="https://publications.waset.org/abstracts/search?q=Chih-Hsun%20Yang"> Chih-Hsun Yang</a>, <a href="https://publications.waset.org/abstracts/search?q=Meng-Tsan%20Tsai"> Meng-Tsan Tsai</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Optical coherence tomography (OCT) enables to provide advantages of noninvasive imaging, high resolution, and high imaging speed. In this study, we integrated OCT and a CW laser for tumor diagnosis and treatment. The axial and transverse resolutions of the developed OCT system are 3 μm and 1 μm, respectively. The frame rate of OCT system is 30 frames/s. In this study, the tumor cells were implanted into the mice skin and scanned by OCT to observe the morphological and angiographic changes. With OCT imaging, 3D microstructures and skin angiography of mice skin can be simultaneously acquired, which can be utilized for identification of the tumor distribution. Then, the CW laser beam can be accurately controlled to expose on the center of the tumor, according to the OCT results. Moreover, OCT was used to monitor the induced photothermolysis and to evaluate the treatment outcome. The results showed that OCT-guided laser therapy could efficiently improve the treatment outcome and the extra damage induced by CW can be greatly reduced. Such OCT-guided laser therapy system could be a potential tool for dermatological applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=optical%20coherence%20tomography" title="optical coherence tomography">optical coherence tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=laser%20therapy" title=" laser therapy"> laser therapy</a>, <a href="https://publications.waset.org/abstracts/search?q=skin%20tumor" title=" skin tumor"> skin tumor</a>, <a href="https://publications.waset.org/abstracts/search?q=position%20guide" title=" position guide"> position guide</a> </p> <a href="https://publications.waset.org/abstracts/55100/co-registered-identification-and-treatment-of-skin-tumor-with-optical-coherence-tomography-guided-laser-therapy" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/55100.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">280</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1285</span> A Novel Guided Search Based Multi-Objective Evolutionary Algorithm</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=A.%20Baviskar">A. Baviskar</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Sandeep"> C. Sandeep</a>, <a href="https://publications.waset.org/abstracts/search?q=K.%20Shankar"> K. Shankar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Solving Multi-objective Optimization Problems requires faster convergence and better spread. Though existing Evolutionary Algorithms (EA's) are able to achieve this, the computation effort can further be reduced by hybridizing them with innovative strategies. This study is focuses on converging to the pareto front faster while adapting the advantages of Strength Pareto Evolutionary Algorithm-II (SPEA-II) for a better spread. Two different approaches based on optimizing the objective functions independently are implemented. In the first method, the decision variables corresponding to the optima of individual objective functions are strategically used to guide the search towards the pareto front. In the second method, boundary points of the pareto front are calculated and their decision variables are seeded to the initial population. Both the methods are applied to different constrained and unconstrained multi-objective test functions. It is observed that proposed guided search based algorithm gives better convergence and diversity than several well-known existing algorithms (such as NSGA-II and SPEA-II) in considerably less number of iterations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=boundary%20points" title="boundary points">boundary points</a>, <a href="https://publications.waset.org/abstracts/search?q=evolutionary%20algorithms%20%28EA%27s%29" title=" evolutionary algorithms (EA's)"> evolutionary algorithms (EA's)</a>, <a href="https://publications.waset.org/abstracts/search?q=guided%20search" title=" guided search"> guided search</a>, <a href="https://publications.waset.org/abstracts/search?q=strength%20pareto%20evolutionary%20algorithm-II%20%28SPEA-II%29" title=" strength pareto evolutionary algorithm-II (SPEA-II)"> strength pareto evolutionary algorithm-II (SPEA-II)</a> </p> <a href="https://publications.waset.org/abstracts/40983/a-novel-guided-search-based-multi-objective-evolutionary-algorithm" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/40983.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">277</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1284</span> Biochemical Characterization and Structure Elucidation of a New Cytochrome P450 Decarboxylase</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Leticia%20Leandro%20Rade">Leticia Leandro Rade</a>, <a href="https://publications.waset.org/abstracts/search?q=Amanda%20Silva%20de%20Sousa"> Amanda Silva de Sousa</a>, <a href="https://publications.waset.org/abstracts/search?q=Suman%20Das"> Suman Das</a>, <a href="https://publications.waset.org/abstracts/search?q=Wesley%20Generoso"> Wesley Generoso</a>, <a href="https://publications.waset.org/abstracts/search?q=Mayara%20Chagas%20%C3%81vila"> Mayara Chagas Ávila</a>, <a href="https://publications.waset.org/abstracts/search?q=Plinio%20Salmazo%20Vieira"> Plinio Salmazo Vieira</a>, <a href="https://publications.waset.org/abstracts/search?q=Antonio%20Bonomi"> Antonio Bonomi</a>, <a href="https://publications.waset.org/abstracts/search?q=Gabriela%20Persinoti"> Gabriela Persinoti</a>, <a href="https://publications.waset.org/abstracts/search?q=Mario%20Tyago%20Murakami"> Mario Tyago Murakami</a>, <a href="https://publications.waset.org/abstracts/search?q=Thomas%20Michael%20Makris"> Thomas Michael Makris</a>, <a href="https://publications.waset.org/abstracts/search?q=Leticia%20Maria%20Zanphorlin"> Leticia Maria Zanphorlin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Alkenes have an economic appeal, especially in the biofuels field, since they are precursors for drop-in biofuels production, which have similar chemical and physical properties to the conventional fossil fuels, with no oxygen in their composition. After the discovery of the first P450 CYP152 OleTJE in 2011, reported with its unique property of decarboxylating fatty acids (FA), by using hydrogen peroxide as a cofactor and producing 1-alkenes as the main product, the scientific and technological interest in this family of enzymes vastly increased. In this context, the present work presents a new decarboxylase (OleTRN) with low similarity with OleTJE (32%), its biochemical characterization, and structure elucidation. As main results, OleTRN presented a high yield of expression and purity, optimum reaction conditions at 35 °C and pH from 6.5 to 8.0, and higher specificity for oleic acid. Besides that, structure-guided mutations were performed and according to the functional characterizations, it was observed that some mutations presented different specificity and chemoselectivity by varying the chain-length of FA substrates from 12 to 20 carbons. These results are extremely interesting from a biotechnological perspective as those characteristics could diversify the applications and contribute to designing better cytochrome P450 decarboxylases. Considering that peroxygenases have the potential activity of decarboxylating and hydroxylating fatty acids and that the elucidation of the intriguing mechanistic involved in the decarboxylation preferential from OleTJE is still a challenge, the elucidation of OleTRN structure and the functional characterizations of OleTRN and its mutants contribute to new information about CYP152. Besides that, the work also contributed to the discovery of a new decarboxylase with a different selectivity profile from OleTJE, which allows a wide range of applications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=P450" title="P450">P450</a>, <a href="https://publications.waset.org/abstracts/search?q=decarboxylases" title=" decarboxylases"> decarboxylases</a>, <a href="https://publications.waset.org/abstracts/search?q=alkenes" title=" alkenes"> alkenes</a>, <a href="https://publications.waset.org/abstracts/search?q=biofuels" title=" biofuels"> biofuels</a> </p> <a href="https://publications.waset.org/abstracts/140579/biochemical-characterization-and-structure-elucidation-of-a-new-cytochrome-p450-decarboxylase" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140579.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">202</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1283</span> Research of Data Cleaning Methods Based on Dependency Rules</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Yang%20Bao">Yang Bao</a>, <a href="https://publications.waset.org/abstracts/search?q=Shi%20Wei%20Deng"> Shi Wei Deng</a>, <a href="https://publications.waset.org/abstracts/search?q=WangQun%20Lin"> WangQun Lin</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This paper introduces the concept and principle of data cleaning, analyzes the types and causes of dirty data, and proposes several key steps of typical cleaning process, puts forward a well scalability and versatility data cleaning framework, in view of data with attribute dependency relation, designs several of violation data discovery algorithms by formal formula, which can obtain inconsistent data to all target columns with condition attribute dependent no matter data is structured (SQL) or unstructured (NoSQL), and gives 6 data cleaning methods based on these algorithms. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=data%20cleaning" title="data cleaning">data cleaning</a>, <a href="https://publications.waset.org/abstracts/search?q=dependency%20rules" title=" dependency rules"> dependency rules</a>, <a href="https://publications.waset.org/abstracts/search?q=violation%20data%20discovery" title=" violation data discovery"> violation data discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=data%20repair" title=" data repair"> data repair</a> </p> <a href="https://publications.waset.org/abstracts/31348/research-of-data-cleaning-methods-based-on-dependency-rules" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31348.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">564</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1282</span> Data Mining As A Tool For Knowledge Management: A Review </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maram%20Saleh">Maram Saleh</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Knowledge has become an essential resource in today’s economy and become the most important asset of maintaining competition advantage in organizations. The importance of knowledge has made organizations to manage their knowledge assets and resources through all multiple knowledge management stages such as: Knowledge Creation, knowledge storage, knowledge sharing and knowledge use. Researches on data mining are continues growing over recent years on both business and educational fields. Data mining is one of the most important steps of the knowledge discovery in databases process aiming to extract implicit, unknown but useful knowledge and it is considered as significant subfield in knowledge management. Data miming have the great potential to help organizations to focus on extracting the most important information on their data warehouses. Data mining tools and techniques can predict future trends and behaviors, allowing businesses to make proactive, knowledge-driven decisions. This review paper explores the applications of data mining techniques in supporting knowledge management process as an effective knowledge discovery technique. In this paper, we identify the relationship between data mining and knowledge management, and then focus on introducing some application of date mining techniques in knowledge management for some real life domains. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Data%20Mining" title="Data Mining">Data Mining</a>, <a href="https://publications.waset.org/abstracts/search?q=Knowledge%20management" title=" Knowledge management"> Knowledge management</a>, <a href="https://publications.waset.org/abstracts/search?q=Knowledge%20discovery" title=" Knowledge discovery"> Knowledge discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=Knowledge%20creation." title=" Knowledge creation."> Knowledge creation.</a> </p> <a href="https://publications.waset.org/abstracts/137030/data-mining-as-a-tool-for-knowledge-management-a-review" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/137030.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">208</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1281</span> Open educational Resources' Metadata: Towards the First Star to Quality of Open Educational Resources</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Audrey%20Romero-Pelaez">Audrey Romero-Pelaez</a>, <a href="https://publications.waset.org/abstracts/search?q=Juan%20Carlos%20Morocho-Yunga"> Juan Carlos Morocho-Yunga</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The increasing amount of open educational resources (OER) published on the web for consumption in teaching and learning environments also generates a growing need to ensure the quality of these resources. The low level of OER discovery is one of the most significant drawbacks when faced with its reuse, and as a consequence, high-quality educational resources can go unnoticed. Metadata enables the discovery of resources on the web. The purpose of this study is to lay the foundations for open educational resources to achieve their first quality star within the Quality4OER Framework. In this study, we evaluate the quality of OER metadata and establish the main guidelines on metadata quality in this context. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=open%20educational%20resources" title="open educational resources">open educational resources</a>, <a href="https://publications.waset.org/abstracts/search?q=OER%20quality" title=" OER quality"> OER quality</a>, <a href="https://publications.waset.org/abstracts/search?q=quality%20metadata" title=" quality metadata"> quality metadata</a> </p> <a href="https://publications.waset.org/abstracts/129865/open-educational-resources-metadata-towards-the-first-star-to-quality-of-open-educational-resources" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/129865.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">240</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1280</span> Endoscopic Ultrasound-Guided Choledochoduodenostomy in an Advanced Extrahepatic Cholangiocarcinoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Diego%20Carrasco">Diego Carrasco</a>, <a href="https://publications.waset.org/abstracts/search?q=Catarina%20Freitas"> Catarina Freitas</a>, <a href="https://publications.waset.org/abstracts/search?q=Hugo%20Rio%20Tinto"> Hugo Rio Tinto</a>, <a href="https://publications.waset.org/abstracts/search?q=Ricardo%20Rio%20Tinto"> Ricardo Rio Tinto</a>, <a href="https://publications.waset.org/abstracts/search?q=Nuno%20Couto"> Nuno Couto</a>, <a href="https://publications.waset.org/abstracts/search?q=Joaquim%20Gago"> Joaquim Gago</a>, <a href="https://publications.waset.org/abstracts/search?q=Carlos%20Carvalho"> Carlos Carvalho</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Endoscopic ultrasound-guided choledochoduodenostomy (EUS-CD) to drain the gallbladder can be a palliative care procedure for non-surgical oncologic patients with cholelithiasis and cholangitis process. Case description: A 59-years old Caucasian male diagnosed with extrahepatic cholangiocarcinoma with multiple liver, lung and peritoneum metastasis, unresponsive to treatment with gemcitabine/cisplatin, presented in the institution with fever, hypotension, and severe upper right abdominal pain secondary to cholelithiasis and cholangitis process. The patient was admitted and started on large spectrum antibiotics plus fluid-challenge. Afterward, a percutaneous transhepatic biliary drainage (PTBD) was performed to drain the gallbladder. This procedure temporarily stabilized the patient. However, the definitive solution required gallbladder removal. Since the patient exhibited an advanced oncologic disease and poor response to the chemotherapy, he was not a candidate for surgical intervention. Diagnostic Pathways: A self-expanding metal stent was placed from the duodenum into the bile duct by endoscopic ultrasound-guided. The stent allowed efficient drainage of the contrast from the gallbladder at the end of the endoscopic procedure. Conclusion and Discussion: The stent allowed efficient drainage of the contrast from the gallbladder at the end of the endoscopic procedure and successfully reversed the cholangitis process. EUS-CD is an effective and safe technique and can be used as a palliative care procedure for non-surgical oncologic patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=palliative%20care" title="palliative care">palliative care</a>, <a href="https://publications.waset.org/abstracts/search?q=cholangiocarcinoma" title=" cholangiocarcinoma"> cholangiocarcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=choledochoduodenostomy" title=" choledochoduodenostomy"> choledochoduodenostomy</a>, <a href="https://publications.waset.org/abstracts/search?q=endoscopic%20ultrasound-guided" title=" endoscopic ultrasound-guided"> endoscopic ultrasound-guided</a> </p> <a href="https://publications.waset.org/abstracts/140682/endoscopic-ultrasound-guided-choledochoduodenostomy-in-an-advanced-extrahepatic-cholangiocarcinoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/140682.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">185</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1279</span> Air-Coupled Ultrasonic Testing for Non-Destructive Evaluation of Various Aerospace Composite Materials by Laser Vibrometry</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=J.%20Vyas">J. Vyas</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Kazys"> R. Kazys</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Sestoke"> J. Sestoke</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Air-coupled ultrasonic is the contactless ultrasonic measurement approach which has become widespread for material characterization in Aerospace industry. It is always essential for the requirement of lightest weight, without compromising the durability. To archive the requirements, composite materials are widely used. This paper yields analysis of the air-coupled ultrasonics for composite materials such as CFRP (Carbon Fibre Reinforced Polymer) and GLARE (Glass Fiber Metal Laminate) and honeycombs for the design of modern aircrafts. Laser vibrometry could be the key source of characterization for the aerospace components. The air-coupled ultrasonics fundamentals, including principles, working modes and transducer arrangements used for this purpose is also recounted in brief. The emphasis of this paper is to approach the developed NDT techniques based on the ultrasonic guided waves applications and the possibilities of use of laser vibrometry in different materials with non-contact measurement of guided waves. 3D assessment technique which employs the single point laser head using, automatic scanning relocation of the material to assess the mechanical displacement including pros and cons of the composite materials for aerospace applications with defects and delaminations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=air-coupled%20ultrasonics" title="air-coupled ultrasonics">air-coupled ultrasonics</a>, <a href="https://publications.waset.org/abstracts/search?q=contactless%20measurement" title=" contactless measurement"> contactless measurement</a>, <a href="https://publications.waset.org/abstracts/search?q=laser%20interferometry" title=" laser interferometry"> laser interferometry</a>, <a href="https://publications.waset.org/abstracts/search?q=NDT" title=" NDT"> NDT</a>, <a href="https://publications.waset.org/abstracts/search?q=ultrasonic%20guided%20waves" title=" ultrasonic guided waves"> ultrasonic guided waves</a> </p> <a href="https://publications.waset.org/abstracts/87212/air-coupled-ultrasonic-testing-for-non-destructive-evaluation-of-various-aerospace-composite-materials-by-laser-vibrometry" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/87212.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">239</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1278</span> Screening for Hit Identification against Mycobacterium abscessus </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Jichan%20Jang">Jichan Jang</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Mycobacterium abscessus is a rapidly growing life-threatening mycobacterium with multiple drug-resistance mechanisms. In this study, we screened the library to identify active molecules targeting Mycobacterium abscessus using resazurin live/dead assays. In this screening assay, the Z-factor was 0.7, as an indication of the statistical confidence of the assay. A cut-off of 80% growth inhibition in the screening resulted in the identification of four different compounds at a single concentration (20 μM). Dose-response curves identified three different hit candidates, which generated good inhibitory curves. All hit candidates were expected to have different molecular targets. Thus, we found that compound X, identified, may be a promising candidate in the M. abscessus drug discovery pipeline. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mycobacterium%20abscessus" title="Mycobacterium abscessus">Mycobacterium abscessus</a>, <a href="https://publications.waset.org/abstracts/search?q=antibiotics" title=" antibiotics"> antibiotics</a>, <a href="https://publications.waset.org/abstracts/search?q=drug%20discovery" title=" drug discovery"> drug discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=emerging%20Pathogen" title=" emerging Pathogen"> emerging Pathogen</a> </p> <a href="https://publications.waset.org/abstracts/91908/screening-for-hit-identification-against-mycobacterium-abscessus" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91908.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">209</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1277</span> Improving Cryptographically Generated Address Algorithm in IPv6 Secure Neighbor Discovery Protocol through Trust Management </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=M.%20Moslehpour">M. Moslehpour</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Khorsandi"> S. Khorsandi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> As transition to widespread use of IPv6 addresses has gained momentum, it has been shown to be vulnerable to certain security attacks such as those targeting Neighbor Discovery Protocol (NDP) which provides the address resolution functionality in IPv6. To protect this protocol, Secure Neighbor Discovery (SEND) is introduced. This protocol uses Cryptographically Generated Address (CGA) and asymmetric cryptography as a defense against threats on integrity and identity of NDP. Although SEND protects NDP against attacks, it is computationally intensive due to Hash2 condition in CGA. To improve the CGA computation speed, we parallelized CGA generation process and used the available resources in a trusted network. Furthermore, we focused on the influence of the existence of malicious nodes on the overall load of un-malicious ones in the network. According to the evaluation results, malicious nodes have adverse impacts on the average CGA generation time and on the average number of tries. We utilized a Trust Management that is capable of detecting and isolating the malicious node to remove possible incentives for malicious behavior. We have demonstrated the effectiveness of the Trust Management System in detecting the malicious nodes and hence improving the overall system performance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=CGA" title="CGA">CGA</a>, <a href="https://publications.waset.org/abstracts/search?q=ICMPv6" title=" ICMPv6"> ICMPv6</a>, <a href="https://publications.waset.org/abstracts/search?q=IPv6" title=" IPv6"> IPv6</a>, <a href="https://publications.waset.org/abstracts/search?q=malicious%20node" title=" malicious node"> malicious node</a>, <a href="https://publications.waset.org/abstracts/search?q=modifier" title=" modifier"> modifier</a>, <a href="https://publications.waset.org/abstracts/search?q=NDP" title=" NDP"> NDP</a>, <a href="https://publications.waset.org/abstracts/search?q=overall%20load" title=" overall load"> overall load</a>, <a href="https://publications.waset.org/abstracts/search?q=SEND" title=" SEND"> SEND</a>, <a href="https://publications.waset.org/abstracts/search?q=trust%20management" title=" trust management"> trust management</a> </p> <a href="https://publications.waset.org/abstracts/41739/improving-cryptographically-generated-address-algorithm-in-ipv6-secure-neighbor-discovery-protocol-through-trust-management" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/41739.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">184</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1276</span> An Animation-Based Resource for Screening Emotional and Behavioural Distress in Children Aged 6 to 12</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zoe%20Lynch">Zoe Lynch</a>, <a href="https://publications.waset.org/abstracts/search?q=Kirsty%20Zieschank"> Kirsty Zieschank</a> </p> <p class="card-text"><strong>Abstract:</strong></p> There are several factors that compromise the utility and wide-spread use of existing emotional and behavioural distress screening instruments. Some of these factors include lengthy administration times, high costs, feasibility issues, and a lack of self-report options for children under 12 years of age. This animation-based resource was developed to overcome as many of these factors as possible. Developed for educators and medical and mental health professionals, this resource offers children a self-guided mechanism for reporting any current emotional and behavioural distress. An avatar assistant, selected by the child, accompanies them through each stage of the screening process, offering further instruction if prompted. Children enter their age and gender before viewing comparative animations conveying common childhood emotional and behavioural difficulties. The child then selects the most relatable animations, along with the frequency with which they experience the depicted emotions. From a perspective of intellectual development, an engaging, animated format means that outcomes will not be constrained by children’s reading, writing, cognitive, or verbal expression abilities. Having been user-tested with children aged 6 to 12, this resource shows promising results as a self-guided screening instrument. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=animation-based%20screening%20instrument" title="animation-based screening instrument">animation-based screening instrument</a>, <a href="https://publications.waset.org/abstracts/search?q=mental%20health" title=" mental health"> mental health</a>, <a href="https://publications.waset.org/abstracts/search?q=primary-aged%20children" title=" primary-aged children"> primary-aged children</a>, <a href="https://publications.waset.org/abstracts/search?q=self-guided" title=" self-guided"> self-guided</a> </p> <a href="https://publications.waset.org/abstracts/86653/an-animation-based-resource-for-screening-emotional-and-behavioural-distress-in-children-aged-6-to-12" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/86653.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">158</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1275</span> A Comparison of Implant Stability between Implant Placed without Bone Graft versus with Bone Graft Using Guided Bone Regeneration (GBR) Technique: A Resonance Frequency Analysis</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=R.%20Janyaphadungpong">R. Janyaphadungpong</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Pimkhaokham"> A. Pimkhaokham</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This prospective clinical study determined the insertion torque (IT) value and monitored the changes in implant stability quotient (ISQ) values during the 12 weeks healing period from implant placement without bone graft (control group) and with bone graft using the guided bone regeneration (GBR) technique (study group). The relationship between the IT and ISQ values of the implants was also assessed. The control and study groups each consisted of 6 patients with 8 implants per group. The ASTRA TECH Implant System™ EV 4.2 mm in diameter was placed in the posterior mandibular region. In the control group, implants were placed in bone without bone graft, whereas in the study group implants were placed simultaneously with the GBR technique at favorable bone defect. IT (Ncm) of each implant was recorded when fully inserted. ISQ values were obtained from the Osstell® ISQ at the time of implant placement, and at 2, 4, 8, and 12 weeks. No difference in IT was found between groups (P = 0.320). The ISQ values in the control group were significantly higher than in the study group at the time of implant placement and at 4 weeks. There was no significant association between IT and ISQ values either at baseline or after the 12 weeks. At 12 weeks of healing, the control and study groups displayed different trends. Mean ISQ values for the control group decreased over the first 2 weeks and then started to increase. ISQ value increases were statistically significant at 8 weeks and later, whereas mean ISQ values in the study group decreased over the first 4 weeks and then started to increase, with statistical significance after 12 weeks. At 12 weeks, all implants achieved osseointegration with mean ISQ values over the threshold value (ISQ>70). These results indicated that implants, in which guided bone regeneration technique was performed during implant placement for treating favorable bone defects, were as predictable as implants placed without bone graft. However, loading in implants placed with the GBR technique for correcting favorable bone defects should be performed after 12 weeks of healing to ensure implant stability and osseointegration. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=dental%20implant" title="dental implant">dental implant</a>, <a href="https://publications.waset.org/abstracts/search?q=favorable%20bone%20defect" title=" favorable bone defect"> favorable bone defect</a>, <a href="https://publications.waset.org/abstracts/search?q=guided%20bone%20regeneration%20technique" title=" guided bone regeneration technique"> guided bone regeneration technique</a>, <a href="https://publications.waset.org/abstracts/search?q=implant%20stability" title=" implant stability"> implant stability</a> </p> <a href="https://publications.waset.org/abstracts/62198/a-comparison-of-implant-stability-between-implant-placed-without-bone-graft-versus-with-bone-graft-using-guided-bone-regeneration-gbr-technique-a-resonance-frequency-analysis" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/62198.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">296</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1274</span> Proposing an Architecture for Drug Response Prediction by Integrating Multiomics Data and Utilizing Graph Transformers</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Nishank%20Raisinghani">Nishank Raisinghani</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Efficiently predicting drug response remains a challenge in the realm of drug discovery. To address this issue, we propose four model architectures that combine graphical representation with varying positions of multiheaded self-attention mechanisms. By leveraging two types of multi-omics data, transcriptomics and genomics, we create a comprehensive representation of target cells and enable drug response prediction in precision medicine. A majority of our architectures utilize multiple transformer models, one with a graph attention mechanism and the other with a multiheaded self-attention mechanism, to generate latent representations of both drug and omics data, respectively. Our model architectures apply an attention mechanism to both drug and multiomics data, with the goal of procuring more comprehensive latent representations. The latent representations are then concatenated and input into a fully connected network to predict the IC-50 score, a measure of cell drug response. We experiment with all four of these architectures and extract results from all of them. Our study greatly contributes to the future of drug discovery and precision medicine by looking to optimize the time and accuracy of drug response prediction. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=drug%20discovery" title="drug discovery">drug discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=transformers" title=" transformers"> transformers</a>, <a href="https://publications.waset.org/abstracts/search?q=graph%20neural%20networks" title=" graph neural networks"> graph neural networks</a>, <a href="https://publications.waset.org/abstracts/search?q=multiomics" title=" multiomics"> multiomics</a> </p> <a href="https://publications.waset.org/abstracts/169926/proposing-an-architecture-for-drug-response-prediction-by-integrating-multiomics-data-and-utilizing-graph-transformers" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/169926.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">153</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1273</span> Design and Implementation Guidance System of Guided Rocket RKX-200 Using Optimal Guidance Law</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Amalia%20Sholihati">Amalia Sholihati</a>, <a href="https://publications.waset.org/abstracts/search?q=Bambang%20Riyanto%20Trilaksono"> Bambang Riyanto Trilaksono</a> </p> <p class="card-text"><strong>Abstract:</strong></p> As an island nation, is a necessity for the Republic of Indonesia to have a capable military defense on land, sea or air that the development of military weapons such as rockets for air defense becomes very important. RKX rocket-200 is one of the guided missiles which are developed by consortium Indonesia and coordinated by LAPAN that serve to intercept the target. RKX-200 is designed to have the speed of Mach 0.5-0.9. RKX rocket-200 belongs to the category two-stage rocket that control is carried out on the second stage when the rocket has separated from the booster. The requirement for better performance to intercept missiles with higher maneuverability continues to push optimal guidance law development, which is derived from non-linear equations. This research focused on the design and implementation of a guidance system based OGL on the rocket RKX-200 while considering the limitation of rockets such as aerodynamic rocket and actuator. Guided missile control system has three main parts, namely, guidance system, navigation system and autopilot systems. As for other parts such as navigation systems and other supporting simulated on MATLAB based on the results of previous studies. In addition to using the MATLAB simulation also conducted testing with hardware-based ARM TWR-K60D100M conjunction with a navigation system and nonlinear models in MATLAB using Hardware-in-the-Loop Simulation (HILS). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=RKX-200" title="RKX-200">RKX-200</a>, <a href="https://publications.waset.org/abstracts/search?q=guidance%20system" title=" guidance system"> guidance system</a>, <a href="https://publications.waset.org/abstracts/search?q=optimal%20guidance%20law" title=" optimal guidance law"> optimal guidance law</a>, <a href="https://publications.waset.org/abstracts/search?q=Hils" title=" Hils"> Hils</a> </p> <a href="https://publications.waset.org/abstracts/57098/design-and-implementation-guidance-system-of-guided-rocket-rkx-200-using-optimal-guidance-law" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/57098.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">254</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1272</span> Ontology-Driven Knowledge Discovery and Validation from Admission Databases: A Structural Causal Model Approach for Polytechnic Education in Nigeria</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bernard%20Igoche%20Igoche">Bernard Igoche Igoche</a>, <a href="https://publications.waset.org/abstracts/search?q=Olumuyiwa%20Matthew"> Olumuyiwa Matthew</a>, <a href="https://publications.waset.org/abstracts/search?q=Peter%20Bednar"> Peter Bednar</a>, <a href="https://publications.waset.org/abstracts/search?q=Alexander%20Gegov"> Alexander Gegov</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This study presents an ontology-driven approach for knowledge discovery and validation from admission databases in Nigerian polytechnic institutions. The research aims to address the challenges of extracting meaningful insights from vast amounts of admission data and utilizing them for decision-making and process improvement. The proposed methodology combines the knowledge discovery in databases (KDD) process with a structural causal model (SCM) ontological framework. The admission database of Benue State Polytechnic Ugbokolo (Benpoly) is used as a case study. The KDD process is employed to mine and distill knowledge from the database, while the SCM ontology is designed to identify and validate the important features of the admission process. The SCM validation is performed using the conditional independence test (CIT) criteria, and an algorithm is developed to implement the validation process. The identified features are then used for machine learning (ML) modeling and prediction of admission status. The results demonstrate the adequacy of the SCM ontological framework in representing the admission process and the high predictive accuracies achieved by the ML models, with k-nearest neighbors (KNN) and support vector machine (SVM) achieving 92% accuracy. The study concludes that the proposed ontology-driven approach contributes to the advancement of educational data mining and provides a foundation for future research in this domain. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=admission%20databases" title="admission databases">admission databases</a>, <a href="https://publications.waset.org/abstracts/search?q=educational%20data%20mining" title=" educational data mining"> educational data mining</a>, <a href="https://publications.waset.org/abstracts/search?q=machine%20learning" title=" machine learning"> machine learning</a>, <a href="https://publications.waset.org/abstracts/search?q=ontology-driven%20knowledge%20discovery" title=" ontology-driven knowledge discovery"> ontology-driven knowledge discovery</a>, <a href="https://publications.waset.org/abstracts/search?q=polytechnic%20education" title=" polytechnic education"> polytechnic education</a>, <a href="https://publications.waset.org/abstracts/search?q=structural%20causal%20model" title=" structural causal model"> structural causal model</a> </p> <a href="https://publications.waset.org/abstracts/184064/ontology-driven-knowledge-discovery-and-validation-from-admission-databases-a-structural-causal-model-approach-for-polytechnic-education-in-nigeria" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/184064.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">64</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1271</span> Discovery the Relics of Buddhist Stupa at Thanesar, Kurukshetra</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Chander%20Shekhar">Chander Shekhar</a>, <a href="https://publications.waset.org/abstracts/search?q=Manoj%20Kumar"> Manoj Kumar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Present paper deal with the discovery of the stupa’s relics which belongs to the Kushana period. These remains were found during the scientific clearance work at a mound near Brahma-SarovarThanesar, Kurukshetra. This archaeological work was done by Department of Archaeology & Museums Haryana Government. The relics of stupa show that it would have been similar to Assandh and Damekhstupa. As per-Buddhist literature, GoutamBudhha reached Thanesar. In memory of Buddh’s Journey, King Ashoka built a big Stupa at Thanesar on the bank of Sarasvati River. Chinese pilgrim Yuan Chuang also referred a Monastery and stupa near Aujas-ghatof Brahma-sarovar. It may be part of that settlement which was mentioned by Yuan Chuang. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=archaeology" title="archaeology">archaeology</a>, <a href="https://publications.waset.org/abstracts/search?q=stupa" title=" stupa"> stupa</a>, <a href="https://publications.waset.org/abstracts/search?q=buddhism" title=" buddhism"> buddhism</a>, <a href="https://publications.waset.org/abstracts/search?q=excavtoin" title=" excavtoin"> excavtoin</a> </p> <a href="https://publications.waset.org/abstracts/145977/discovery-the-relics-of-buddhist-stupa-at-thanesar-kurukshetra" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/145977.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">193</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1270</span> Radio-Guided Surgery with β− Radiation: Test on Ex-Vivo Specimens</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=E.%20Solfaroli%20Camillocci">E. Solfaroli Camillocci</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Mancini-Terracciano"> C. Mancini-Terracciano</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Bocci"> V. Bocci</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Carollo"> A. Carollo</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Colandrea"> M. Colandrea</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Collamati"> F. Collamati</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Cremonesi"> M. Cremonesi</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20E.%20Ferrari"> M. E. Ferrari</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Ferroli"> P. Ferroli</a>, <a href="https://publications.waset.org/abstracts/search?q=F.%20Ghielmetti"> F. Ghielmetti</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20M.%20Grana"> C. M. Grana</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Marafini"> M. Marafini</a>, <a href="https://publications.waset.org/abstracts/search?q=S.%20Morganti"> S. Morganti</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Patane"> M. Patane</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Pedroli"> G. Pedroli</a>, <a href="https://publications.waset.org/abstracts/search?q=B.%20Pollo"> B. Pollo</a>, <a href="https://publications.waset.org/abstracts/search?q=L.%20Recchia"> L. Recchia</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Russomando"> A. Russomando</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Schiariti"> M. Schiariti</a>, <a href="https://publications.waset.org/abstracts/search?q=M.%20Toppi"> M. Toppi</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Traini"> G. Traini</a>, <a href="https://publications.waset.org/abstracts/search?q=R.%20Faccini"> R. Faccini</a> </p> <p class="card-text"><strong>Abstract:</strong></p> A Radio-Guided Surgery technique exploiting β− emitting radio-tracers has been suggested to overcome the impact of the large penetration of γ radiation. The detection of electrons in low radiation background provides a clearer delineation of the margins of lesioned tissues. As a start, the clinical cases were selected between the tumors known to express receptors to a β− emitting radio-tracer: 90Y-labelled DOTATOC. The results of tests on ex-vivo specimens of meningioma brain tumor and abdominal neuroendocrine tumors are presented. Voluntary patients were enrolled according to the standard uptake value (SUV > 2 g/ml) and the expected tumor-to-non-tumor ratios (TNR∼10) estimated from PET images after administration of 68Ga-DOTATOC. All these tests validated this technique yielding a significant signal on the bulk tumor and a negligible background from the nearby healthy tissue. Even injecting as low as 1.4 MBq/kg of radiotracer, tumor remnants of 0.1 ml would be detectable. The negligible medical staff exposure was confirmed and among the biological wastes only urine had a significant activity. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ex-vivo%20test" title="ex-vivo test">ex-vivo test</a>, <a href="https://publications.waset.org/abstracts/search?q=meningioma" title=" meningioma"> meningioma</a>, <a href="https://publications.waset.org/abstracts/search?q=neuroendocrine%20tumor" title=" neuroendocrine tumor"> neuroendocrine tumor</a>, <a href="https://publications.waset.org/abstracts/search?q=radio-guided%20surgery" title=" radio-guided surgery"> radio-guided surgery</a> </p> <a href="https://publications.waset.org/abstracts/72423/radio-guided-surgery-with-v-radiation-test-on-ex-vivo-specimens" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/72423.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">294</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1269</span> Khilafat from Khilafat-e-Rashida: The Rightly Guided the Only Form of Governance to Unite Muslim Countries</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Zoaib%20Mirza">Zoaib Mirza</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Half of the Muslim countries in the world have declared Islam the state religion in their constitutions. Yet, none of these countries have implemented authentic Islamic laws in line with the Quran (Holy Book), practices of Prophet Mohammad (P.B.U.H) called the Sunnah, and his four successors known as the Rightly Guided - Khalifa. Since their independence, these countries have adopted different government systems like Democracy, Dictatorship, Republic, Communism, and Monarchy. Instead of benefiting the people, these government systems have put these countries into political, social, and economic crises. These Islamic countries do not have equal representation and membership in worldwide political forums. Western countries lead these forums. Therefore, it is now imperative for the Muslim leaders of all these countries to collaborate, reset, and implement the original Islamic form of government, which led to the prosperity and success of people, including non-Muslims, 1400 years ago. They should unite as one nation under Khalifat, which means establishing the authority of Allah (SWT) and following the divine commandments related to the social, political, and economic systems. As they have declared Islam in their constitution, they should work together to apply the divine framework of the governance revealed by Allah (SWT) and implemented by Prophet Mohammad (P.B.U.H) and his four successors called Khalifas. This paper provides an overview of the downfall and the end of the Khalifat system by 1924, the ways in which the West caused political, social, and economic crises in the Muslim countries, and finally, a summary of the social, political, and economic systems implemented by the Prophet Mohammad (P.B.U.H) and his successors, Khalifas, called the Rightly Guided – Hazrat Abu Bakr (RA), Hazrat Omar (RA), Hazrat Usman (RA), and Hazrat Ali (RA). <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=khalifat" title="khalifat">khalifat</a>, <a href="https://publications.waset.org/abstracts/search?q=khilafat-e-Rashida" title=" khilafat-e-Rashida"> khilafat-e-Rashida</a>, <a href="https://publications.waset.org/abstracts/search?q=the%20rightly%20guided" title=" the rightly guided"> the rightly guided</a>, <a href="https://publications.waset.org/abstracts/search?q=colonization" title=" colonization"> colonization</a>, <a href="https://publications.waset.org/abstracts/search?q=capitalism" title=" capitalism"> capitalism</a>, <a href="https://publications.waset.org/abstracts/search?q=neocolonization" title=" neocolonization"> neocolonization</a>, <a href="https://publications.waset.org/abstracts/search?q=government%20systems" title=" government systems"> government systems</a> </p> <a href="https://publications.waset.org/abstracts/158957/khilafat-from-khilafat-e-rashida-the-rightly-guided-the-only-form-of-governance-to-unite-muslim-countries" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158957.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">120</span> </span> </div> </div> <ul class="pagination"> <li class="page-item"><a class="page-link" href="https://publications.waset.org/abstracts/search?q=guided%20discovery&page=1" 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