帅心涛 | 中山大学化学学院

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href="/zh-hans/taxonomy/term/257">师资队伍</a> </li> <li class="space"><i class="icon"></i></li><li> <a href="/zh-hans/TeachersTeam/JieQingFund">国家杰青</a> </li> <li class="space"><i class="icon"></i></li><li> 帅心涛 </li> </ul> </nav> </div> </div> </div> <div class="row"> <div class="col-sm-12 col-md-3 hidden-xs region-left"> <div class="block-region-left"> <div class="views-element-container block" data-block-plugin-id="views_block:teacher-block_1"> <div><div class="js-view-dom-id-2d935f2d52e3ac884c0c4619a0c0e19738cde3ad97b8ee49b56404ced7590ba5"> <div class="views-row"><div class="views-field views-field-image"><div class="field-content"> <img loading="lazy" src="/sites/default/files/styles/image_style_2/public/2018-07/%E5%B8%85%E5%BF%83%E6%B6%9B.jpg?itok=tJsWcit0" width="300" height="400" alt="帅心涛" typeof="foaf:Image" /> </div></div><div class="views-field views-field-title"><span class="field-content"></br> <h2 class="align-center"><strong>帅心涛 </strong></h2> </br></span></div><div class="views-field views-field-category"><div class="field-content"><p class="t-c">教授</p> </div></div></div> </div> </div> </div> <div data-block-plugin-id="entity_field:node:field_tel" class="block"> <div class="field field-field-tel field-type-string field-label-inline"> <div class="field-label">办公电话</div> <div class="field-item">020- 84110365</div> </div> </div> </div> </div> <div class="col-sm-12 col-md-9 region-right"> <div class="block-region-right"> <div data-block-plugin-id="entity_field:node:body" class="block"> <div class="field field-body field-type-text-with-summary field-label-hidden field-item"><p>基本情况</p> <p>姓名：帅心涛</p> <p>性别：男</p> <p>出生年月：暂未填写</p> <p>籍贯：暂未填写</p> <p>职位：</p> <p>化学与化工学院教授，中山医学院双聘教授'。</p> <h3>联系方式</h3> <p>电话：020- 84110365</p> <p>传真：020- 84112245</p> <p>邮箱：暂未填写</p> <p>通讯地址：广东省广州市中山大学化学与化学工程学院</p> <p>邮编：510275</p> <p>个人网站：暂未填写</p> <h3>教育经历</h3> <p>1986年—1996年：北京理工大学化学与材料学院学习，获学士、硕士及博士学位。 <strong> </strong></p> <h3>工作经历</h3> <p>2016.1 材料科学与工程学院教授，化学与化学工程学院、中山医学院双聘教授。<br> 2010年6月—2010年9月：美国得克萨斯大学西南医学中心访问教授。 <br> 2005年—2016年：中山大学化学与化工学院、中山医学院双聘教授。 <br> 2003年—2005年：美国凯斯西储大学研究人员。 <br> 2002年：德国马尔堡大学洪堡学者。 <strong> </strong> <br> 2001年：美国北卡州立大学访问学者。 <br> 1998年—2000年：中国科学院化学研究所副研究员。 </p> <h3>讲授课程</h3> <p>《功能高分子》、《材料力学》等。</p> <h3>科研方向</h3> <p>以聚合物纳米医学技术为平台的疾病（例如：肿瘤）诊断及治疗研究，主要涉及下述两个方面： <br> 1. 肿瘤等疾病早期诊断纳米探针研究 <br> 2. 小分子药物及核酸药物（例如：基因及siRNA）的靶向传输及控制释放研究。</p> <h3>科研项目</h3> <p>  主持国家自然科学基金重点项目1项、海外合作青年基金项目1项（原杰青B，共同主持）、面上项目3项，主持863计划项目1项；此外主持或参加863计划、国家自然科学基金、科技部十一五重大新药创制专项、“高等学校学科创新引智计划”（111计划）等项目20余项，主要包括： <br> 1. 国家自然科学基金-广东省联合基金重点项目，“骨髓间充质干细胞肝内移植后定向分化的活体基因成像研究”，2011年1月至2014年12月，副组长（co-PI）； <br> 2. 科技部“863”探索导向项目，“用于乳腺癌早期诊断具有双重肿瘤靶向功能的MRI对比剂”，2009年至2011年，主持； <br> 3. 国家自然科学基金重点项目，“肿瘤靶向药物及siRNA联合传输多功能纳米载体研究”，2009年至2012年，主持； <br> 4. 国家自然科学基金海外及港澳青年学者合作研究基金项目（原杰青B），“医用高分子、高分子药物”，2008年至2010年，共同主持； <br> 5. 国家自然科学基金面上项目，“用于肿瘤靶向性基因传输的新型非病毒聚合物载体的制备及性能优化”，已结题，2007年至2009年，主持； <br> 6. 国家自然科学基金面上项目，“用于肿瘤治疗及心血管疾病与早期肿瘤诊断的双重靶向传输及MRI可见的先进聚合物纳米胶束的研究”，已结题，主持； <br> 7. 国家自然科学基金面上项目，“超稳定及智能型聚合物纳米胶束的制备及药物传送与控释”，已结题，主持； <br> 8. 科技部十一五重大新药创制专项，“口服微丸制剂国际化关键技术”，2009年至2011年，主要成员。（项目负责人为药学院吴传斌教授）； <br> 9. 科技部“863计划”重点项目，“控制对虾白斑综合症病毒感染的阻断技术”，2007年至2009年，主要成员。（项目负责单位为海洋三所）； <br> 10. 高等学校学科创新引智计划（111计划）项目, “光电及功能分子固体材料创新引智基地”，2008年至2012年，纳米生物技术子课题中方负责人。（项目负责人为理工学院许宁生院士）； <br> 11. 广东省自然科学基金团队项目，“肿瘤靶向金属药物的创新研制与应用”，2010年至2013年，五个负责人之一。（项目协调人为化工学院毛宗万教授）。</p> <h3>获奖情况</h3> <p>暂无资料</p> <h3>论著一览</h3> <p>1. J. Li, X. Yu, Y. Wang, Y. Yuan, Hong Xiao, D. Cheng, X. Shuai*, A reduction and pH dual-sensitive polymeric vector for long-circulating and tumor-targeted siRNA delivery, Adv. Mater. 2014, 26, 8217-8224.<br> 2. T. Yin, P. Wang, J. Li, Y. Wang, B. Zheng, R. Zheng*, D. Cheng, X. Shuai*, Tumor-penetrating codelivery of siRNA and paclitaxel with ultrasound-responsive nanobubbles hetero-assembled from polymeric micelles and liposomes, Biomaterials 2014, 35, 5932-5943.<br> 3.  W. Chen, Y. Yuan, D. Cheng, J. Chen, L. Wang, X. Shuai*, Co-delivery of doxorubicin and siRNA with reduction and pH dual sensitive nanocarrier for synergistic cancer therapy, Small 2014, 10, 2678-2687.<br> 4. C. Wu, J. Li, P. Pang, J. Liu, K. Zhu, D. Li, D. Cheng, J. Chen, X. Shuai*, Hong Shan*, Polymeric vector-mediated gene transfection of MSCs for dual bioluminescent and MRI tracking in vivo, Biomaterials 2014, 28, 8249-8260.<br> 5. C. Qian, Y. Wang, Y. Chen, L. Zeng, Q. Zhang, X. Shuai*, K. Huang*, Suppression of pancreatic tumor growth by targeted arsenic delivery with anti-CD44v6 single chain antibody conjugated nanoparticles, Biomaterials2013, 34, 6175-6184.<br> 6. T. Yin, P. Wang, J. Li, R. Zheng*, B Zheng, D. Cheng, R. Li, J. Lai, X. Shuai*, Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles and liposomes and their therapeutic effect in gliomas, Biomaterials 2013, 34, 4532-4543.<br> 7. Y. Guo, W. Chen, W. Wang, J. Shen*, R. Guo, F. Gong, S. Lin, D. Cheng, G. Chen*, X Shuai*, Simultaneous Diagnosis and Gene Therapy of Immuno-Rejection in Rat Allogeneic Heart Transplantation Model Using a T-Cell-Targeted Theranostic Nanosystem, ACS Nano 2012, 6, 10646-10657.<br> 8. W. Wang, D. Cheng, D. Cheng, F. Gong, X. Miao, X. Shuai*, Design of multifunctional micelle for tumor-targeted intracellular drug release and fluorescent imaging, Adv. Mater. 2012, 24, 115-120.<br> 9. D. Cheng, N. Cao, J. Chen, X. Yu, X. Shuai*, Multifunctional nanocarrier mediated co-delivery of doxorubicin and siRNA for synergistic enhancement of glioma apoptosis in rat, Biomaterials 2012, 33, 1170-1179.<br> 10. J. Dai, S. Lin, D. Cheng, S. Zou, X. Shuai*, Interlayer crosslinked micelle with partially hydrated core showing reduction and pH dual sensitivity for pinpointed intracellular drug release, Angew. Chem. Int. Ed. 2011, 50, 9404 -9408.<br> 11. N. Cao, D. Cheng, S. Zou, H. Ai, J. Gao, X. Shuai*, The synergistic effect of hierarchical assemblies of siRNA and chemotherapeutic drugs co-delivered into hepatic cancer cells, Biomaterials 2011, 32, 2222-2232.<br> 12. J. Dai, S. Zou, Y. Pei, D. Cheng, H. Ai, X. Shuai*, Polyethylenimine-grafted copolymer of poly(L-lysine) and poly(ethylene glycol) for gene delivery, Biomaterials 2011, 32, 1694-1705.<br> 13. B. Liang, M. He, C. Chan, Y. Chen, X. Li, Y. Li, D. Zheng, M. Lin, H. Kung, X. Shuai*, Ying Peng*, The use of folate-PEG-grafted-hybranched-PEI nonviral vector for the inhibition of glioma growth in the rat, Biomaterials2009, 30, 4014-4020.<br> 14. G. Chen*, W. Chen, Z. Wu, R. Yuan, Hua Li, J. Gao, X. Shuai*, MRI-visible polymeric vector bearing CD3 single chain antibody for gene delivery to T cells for immunosuppression, Biomaterials 2009, 30, 1962-1970.<br> 15. N. Nasongkla†, X. Shuai†, H. Ai, B. Weinberg, J. Pink, D. Boothman, J. Gao*, cRGD-functionalized polymer micelles for targeted doxorubicin delivery, Angew. Chem. Int. Edi. 2004, 43, 6323-6327. (†equal contributors).<br> 16. X. Shuai, H. Ai, N. Nasongkla, S. Kim, J. Gao, Micellar Carriers Based on Block Copolymers of Poly(e-caprolactone) and Poly(ethylene glycol) for Doxorubicin Delivery, J. Controlled Release 2004, 98, 415-426.</p> <p><strong>学术积累</strong><br>     发表SCI论文60余篇，他引1500余次。申请发明专利8项。近5年来10多次在国际、国内学术会议上作邀请报告。担任Biomaterials、 Macromolecules、Biomacromolecules等学术期刊审稿人，广东省药学会药物制剂专业委员会副主任委员。中山大学“百人计划”第二层次引进人才，2005年入选教育部“新世纪优秀人才支持计划”， 2010年入选广东省高校“千百十工程”省级培养对象。</p> <h3>相关成果</h3> <p>暂无资料</p> </div> </div> </div> </div> </div> </div> </div> </article> </div> </div> <div id="footer"> <div id="block-footer-2" data-block-plugin-id="block_content:c66c305b-9ef5-4596-9f31-22956d73fa08" class="block"> <div class="field field-body field-type-text-with-summary field-label-hidden field-item"><p> <style type="text/css">* { padding: 0; margin: 0; box-sizing: border-box; } a:link { text-decoration: none; } .t-c { text-align: center; } .t-l { text-align: left; } </style> </p> <div class="inside-lr"> <div class="footer" style="margin-bottom:0px;padding-top:10px;"> <div class="footer_container floatfix footer-t-b" style="margin-bottom:0px;"> <div class="footer_copyright"> <div 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