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(PDF) Maternal-care behavior and life-history traits in house mice (< i> Mus domesticus</i>) artificially selected for high voluntary wheel-running activity | Theodore Garland - Academia.edu

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{"work":{"id":69661281,"created_at":"2022-01-27T10:02:47.948-08:00","from_world_paper_id":193626811,"updated_at":"2024-11-22T21:50:20.277-08:00","_data":{"grobid_abstract":"To test the hypothesis that selective breeding for high voluntary wheel running negatively affects maternal performance in house mice, we observed maternal behavior and compared litter size and mass, in replicate lines of selected (N =4) and control (N=4) mice from generations 20 and 21 of an artificial selection experiment. At generation 21, selected-line females ran 2.8-times more revolutions per day than females from random-bred control lines, when tested at approximately 6 weeks of age as part of the normal selection protocol. After giving birth, dams from selected and control lines exhibited similar frequencies of maternal behaviors and also spent similar amounts of time in general locomotor activity at litter ages of both 9 and 16 days. Dams from selected lines also performed equally well as controls in repeated pup-retrieval trials. At first parturition, selected-line dams averaged 2.4 g smaller in body mass as compared with dams from the control lines; however, neither litter size nor litter mass at birth (generation 20) or at weaning (generation 21) differed significantly between selected and control lines. We conclude that, at least under the husbandry conditions employed, maternal behavior and reproductive output at first parturition are genetically independent of wheel-running behavior.","publication_date":"2002,,","grobid_abstract_attachment_id":"79670350"},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Maternal-care behavior and life-history traits in house mice (\u003c i\u003e Mus domesticus\u003c/i\u003e) artificially selected for high voluntary wheel-running activity","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [31702217]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" 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class="ds-work-card--author-avatar" src="https://0.academia-photos.com/31702217/50736096/38775289/s65_theodore.garland.jpg" />Theodore Garland</a></div><p class="ds-work-card--detail ds2-5-body-sm">2002</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--work-card&quot;,&quot;attachmentId&quot;:79670350,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:&quot;https://www.academia.edu/69661281/Maternal_care_behavior_and_life_history_traits_in_house_mice_i_Mus_domesticus_i_artificially_selected_for_high_voluntary_wheel_running_activity&quot;}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" 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class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="26048410" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26048410/Maternal_care_behavior_and_life_history_traits_in_house_mice_Mus_domesticus_artificially_selected_for_high_voluntary_wheel_running_activity">Maternal-care behavior and life-history traits in house mice (Mus domesticus) artificially selected for high voluntary wheel-running activity</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31702217" href="https://ucriverside.academia.edu/TGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Behavioural Processes, 2002</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Maternal-care behavior and life-history traits in house mice (Mus domesticus) artificially selected for high voluntary wheel-running activity&quot;,&quot;attachmentId&quot;:46386483,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/26048410/Maternal_care_behavior_and_life_history_traits_in_house_mice_Mus_domesticus_artificially_selected_for_high_voluntary_wheel_running_activity&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/26048410/Maternal_care_behavior_and_life_history_traits_in_house_mice_Mus_domesticus_artificially_selected_for_high_voluntary_wheel_running_activity"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="8195523" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/8195523/Artificial_Selection_for_Increased_Wheel_Running_Behavior_in_House_Mice">Artificial Selection for Increased Wheel-Running Behavior in House Mice</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="16061010" href="https://ucriverside.academia.edu/TheodoreGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">1998</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Artificial Selection for Increased Wheel-Running Behavior in House Mice&quot;,&quot;attachmentId&quot;:34626154,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/8195523/Artificial_Selection_for_Increased_Wheel_Running_Behavior_in_House_Mice&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/8195523/Artificial_Selection_for_Increased_Wheel_Running_Behavior_in_House_Mice"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="64361514" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/64361514/Artificial_selection_for_increased_wheel_running_activity_in_house_mice_results_in_decreased_body_mass_at_maturity">Artificial selection for increased wheel-running activity in house mice results in decreased body mass at maturity</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31702217" href="https://ucriverside.academia.edu/TGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">The Journal of experimental biology, 1999</p><p class="ds-related-work--abstract ds2-5-body-sm">To test the hypothesis that body size and activity levels are negatively genetically correlated, we conducted an artificial selection experiment for increased voluntary wheel-running activity in house mice (Mus domesticus). Here, we compare body masses of mice from control and selected lines after 14 generations of selection. In both groups, beginning at weaning and then for 8 weeks, we housed half of the individuals with access to running wheels that were free to rotate and the other half with wheels that were locked to prevent rotation. Mice from selected lines were more active than controls at weaning (21 days) and across the experiment (total revolutions during last week: females 2.5-fold higher, males 2.1-fold higher). At weaning, mice from selected and control lines did not differ significantly in body mass. At 79 days of age, mice from selected lines weighed 13.6 % less than mice from control lines, whereas mice with access to free wheels weighed 4.5 % less than &amp;#39;sedentar...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Artificial selection for increased wheel-running activity in house mice results in decreased body mass at maturity&quot;,&quot;attachmentId&quot;:76432609,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/64361514/Artificial_selection_for_increased_wheel_running_activity_in_house_mice_results_in_decreased_body_mass_at_maturity&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/64361514/Artificial_selection_for_increased_wheel_running_activity_in_house_mice_results_in_decreased_body_mass_at_maturity"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="12689980" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/12689980/Nesting_behavior_of_house_mice_Mus_domesticus_selected_for_increased_wheel_running_activity">Nesting behavior of house mice (Mus domesticus) selected for increased wheel-running activity</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31702217" href="https://ucriverside.academia.edu/TGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2000</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Nesting behavior of house mice (Mus domesticus) selected for increased wheel-running activity&quot;,&quot;attachmentId&quot;:46005492,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/12689980/Nesting_behavior_of_house_mice_Mus_domesticus_selected_for_increased_wheel_running_activity&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/12689980/Nesting_behavior_of_house_mice_Mus_domesticus_selected_for_increased_wheel_running_activity"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="53105106" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/53105106/Mice_Selectively_Bred_for_High_Wheel_Running_Activity_Have_Increased_Growth_Efficiency_During_Lactation">Mice Selectively Bred for High Wheel Running Activity Have Increased Growth Efficiency During Lactation</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="33109137" href="https://independent.academia.edu/GDijk">Gertjan Van Dijk</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Mice Selectively Bred for High Wheel Running Activity Have Increased Growth Efficiency During Lactation&quot;,&quot;attachmentId&quot;:70048558,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/53105106/Mice_Selectively_Bred_for_High_Wheel_Running_Activity_Have_Increased_Growth_Efficiency_During_Lactation&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/53105106/Mice_Selectively_Bred_for_High_Wheel_Running_Activity_Have_Increased_Growth_Efficiency_During_Lactation"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="12690019" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/12690019/Open_Field_Behavior_of_House_Mice_Selectively_Bred_for_High_Voluntary_Wheel_Running">Open-Field Behavior of House Mice Selectively Bred for High Voluntary Wheel-Running</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31702217" href="https://ucriverside.academia.edu/TGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2001</p><p class="ds-related-work--abstract ds2-5-body-sm">Received 1 Sept. 2000—Final 3 May 2001 Open-field behavioral assays are commonly used to test both locomotor activity and emotional- ity in rodents. We performed open-field tests on house mice ( Mus domesticus) from four repli- cate lines genetically selected for high voluntary wheel-running for 22 generations and from four replicate random-bred control lines. Individual mice were recorded by video</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Open-Field Behavior of House Mice Selectively Bred for High Voluntary Wheel-Running&quot;,&quot;attachmentId&quot;:37782785,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/12690019/Open_Field_Behavior_of_House_Mice_Selectively_Bred_for_High_Voluntary_Wheel_Running&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/12690019/Open_Field_Behavior_of_House_Mice_Selectively_Bred_for_High_Voluntary_Wheel_Running"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="12689982" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/12689982/Behaviour_of_house_mice_artificially_selected_for_high_levels_of_voluntary_wheel_running">Behaviour of house mice artificially selected for high levels of voluntary wheel running</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50043409" href="https://independent.academia.edu/JoannaSax">Joanna Sax</a><span>, </span><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31702217" href="https://ucriverside.academia.edu/TGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Animal Behaviour, 1999</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Behaviour of house mice artificially selected for high levels of voluntary wheel running&quot;,&quot;attachmentId&quot;:46005473,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/12689982/Behaviour_of_house_mice_artificially_selected_for_high_levels_of_voluntary_wheel_running&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/12689982/Behaviour_of_house_mice_artificially_selected_for_high_levels_of_voluntary_wheel_running"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="4942559" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/4942559/Behavioral_Traits_are_Affected_by_Selective_Breeding_for_Increased_Wheel_Running_Behavior_in_Mice">Behavioral Traits are Affected by Selective Breeding for Increased Wheel-Running Behavior in Mice</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="6498229" href="https://umcg.academia.edu/FionaReijne">Fiona Reijne</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Behavioral Traits are Affected by Selective Breeding for Increased Wheel-Running Behavior in Mice&quot;,&quot;attachmentId&quot;:32198684,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/4942559/Behavioral_Traits_are_Affected_by_Selective_Breeding_for_Increased_Wheel_Running_Behavior_in_Mice&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/4942559/Behavioral_Traits_are_Affected_by_Selective_Breeding_for_Increased_Wheel_Running_Behavior_in_Mice"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="26048402" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26048402/Are_Voluntary_Wheel_Running_and_Open_Field_Behavior_Correlated_in_Mice_Different_Answers_from_Comparative_and_Artificial_Selection_Approaches">Are Voluntary Wheel Running and Open-Field Behavior Correlated in Mice? Different Answers from Comparative and Artificial Selection Approaches</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31702217" href="https://ucriverside.academia.edu/TGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Behavior Genetics, 2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Are Voluntary Wheel Running and Open-Field Behavior Correlated in Mice? Different Answers from Comparative and Artificial Selection Approaches&quot;,&quot;attachmentId&quot;:46386479,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/26048402/Are_Voluntary_Wheel_Running_and_Open_Field_Behavior_Correlated_in_Mice_Different_Answers_from_Comparative_and_Artificial_Selection_Approaches&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/26048402/Are_Voluntary_Wheel_Running_and_Open_Field_Behavior_Correlated_in_Mice_Different_Answers_from_Comparative_and_Artificial_Selection_Approaches"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="121230413" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/121230413/Variability_of_wheel_running_behavior_in_mice_is_dependent_on_housing_sex_and_genetic_background">Variability of wheel running behavior in mice is dependent on housing, sex, and genetic background</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="47965764" href="https://independent.academia.edu/DietmarPlenz">Dietmar Plenz</a></div><p class="ds-related-work--abstract ds2-5-body-sm">Environmental enrichment (EE) has been increasingly used to enhance and support the physiological fitness and natural behavior of research animals. For mice, which are known to be highly active nocturnal animals that live in large social groups, the introduction of running wheels is a particularly promising approach in EE. When wheels are introduced to their home cage, mice increase their nocturnal locomotion activity by orders of magnitude. However, little is known about how mice share such a readily adopted EE. Here, we studied wheel running in single-housed and group-housed mice. We hypothesized that group-housed mice will compete over the scarce resource of a running wheel leading to a change in overall wheel usage compared to single-housed mice that have exclusive wheel access. We measured wheel locomotion in two strains of single-housed and group-housed mice over multiple 24h periods at sub-second temporal resolution using a custom-designed data acquisition system. We observed...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Variability of wheel running behavior in mice is dependent on housing, sex, and genetic background&quot;,&quot;attachmentId&quot;:116164970,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/121230413/Variability_of_wheel_running_behavior_in_mice_is_dependent_on_housing_sex_and_genetic_background&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/121230413/Variability_of_wheel_running_behavior_in_mice_is_dependent_on_housing_sex_and_genetic_background"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:79670350,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--sticky-ctas&quot;,&quot;attachmentId&quot;:79670350,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_79670350" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="112454819" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/112454819/Selection_for_high_voluntary_wheel_running_increases_speed_and_intermittency_in_house_mice_Mus_domesticus_">Selection for high voluntary wheel-running increases speed and intermittency in house mice (Mus domesticus)</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="31702217" href="https://ucriverside.academia.edu/TGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Experimental Biology, 2001</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Selection for high voluntary wheel-running increases speed and intermittency in house mice (Mus domesticus)&quot;,&quot;attachmentId&quot;:109680261,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/112454819/Selection_for_high_voluntary_wheel_running_increases_speed_and_intermittency_in_house_mice_Mus_domesticus_&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/112454819/Selection_for_high_voluntary_wheel_running_increases_speed_and_intermittency_in_house_mice_Mus_domesticus_"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="1" data-entity-id="71900835" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/71900835/Selective_Breeding_and_Short_Term_Access_to_a_Running_Wheel_Alter_Stride_Characteristics_in_House_Mice">Selective Breeding and Short-Term Access to a Running Wheel Alter Stride Characteristics in House Mice</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="16061010" href="https://ucriverside.academia.edu/TheodoreGarland">Theodore Garland</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Physiological and Biochemical Zoology</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Selective Breeding and Short-Term Access to a Running Wheel Alter Stride Characteristics in House Mice&quot;,&quot;attachmentId&quot;:81056167,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/71900835/Selective_Breeding_and_Short_Term_Access_to_a_Running_Wheel_Alter_Stride_Characteristics_in_House_Mice&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-related-work-grid-card-view-pdf" href="https://www.academia.edu/71900835/Selective_Breeding_and_Short_Term_Access_to_a_Running_Wheel_Alter_Stride_Characteristics_in_House_Mice"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="2" data-entity-id="18100194" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/18100194/Behavioural_differences_in_non_reproductive_adult_females_in_a_long_term_selection_experiment_for_litter_size_in_mice">Behavioural differences in non-reproductive adult females in a long-term selection experiment for litter size in mice</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="38055101" href="https://independent.academia.edu/OddVangen">Odd Vangen</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Applied Animal Behaviour Science, 2000</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Behavioural differences in non-reproductive adult females in a long-term selection experiment for litter size in mice&quot;,&quot;attachmentId&quot;:39876076,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/18100194/Behavioural_differences_in_non_reproductive_adult_females_in_a_long_term_selection_experiment_for_litter_size_in_mice&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span 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Laboratory Mice Selectively Bred for High Wheel-Running Activity</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="5113017" href="https://independent.academia.edu/FernandoGomes1">Fernando Gomes</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Physiological and Biochemical Zoology, 2006</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Effects of Size, Sex, and Voluntary Running Speeds on Costs of Locomotion in Lines of Laboratory Mice Selectively Bred for High Wheel-Running 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