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Adakah tautan antara konsumsi alkohol dan kanker? | DRINKiQ ID
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data-srcset='/~/media/Images/D/drinkiq/Universal/drinkiq--images/in-english/banner-module-images/drinking-and-your-body/alcohol-and-cancer-ill.webp' media="(min-width: 767px)"> <img class="lazy w-100" data-src='/~/media/Images/D/drinkiq/Universal/drinkiq--images/in-english/banner-module-images/drinking-and-your-body/alcohol-and-cancer-ill.webp' alt='Adakah tautan antara konsumsi alkohol dan kanker?'> <noscript> <img src='/~/media/Images/D/drinkiq/Universal/drinkiq--images/in-english/banner-module-images/drinking-and-your-body/alcohol-and-cancer-ill.webp' alt='Adakah tautan antara konsumsi alkohol dan kanker?' /> </noscript> </picture> </div> <figcaption class="caption column-start-1 column-end-13 text-caption"> Adakah tautan antara konsumsi alkohol dan kanker? </figcaption> </div> </div> </section> <section class="config-text pt-0 pb-16"> <div class="container-fluid"> <div class="config-text-content column-start-1 column-end-13"> <p>Kanker adalah penyakit yang kompleks yang memiliki banyak penyebab dan dipengaruhi oleh banyak faktor <a href="#refs1" data-anchor="#refs1"><sup> (1)</sup></a>. Konsumsi alkohol misalnya bir, wine, atau spirit terdistilasi, adalah salah satu faktornya. Banyak risiko kanker yang tidak dapat diubah; yakni genetik dan riwayat keluarga, usia dan ukuran tubuh Anda, serta faktor lingkungan lainnya seperti radiasi dan infeksi virus <a href="#refs2" data-anchor="#refs2"><sup> (2)</sup></a>.</p> <p>Faktor-faktor gaya hidup juga berperan penting dan dapat dimodifikasi untuk mengurangi risiko <a href="#refs2" data-anchor="#refs2"><sup> (2)</sup></a>. Merokok adalah faktor risiko gaya hidup tunggal paling signifikan bagi kebanyakan tipe kanker <a href="#refs3" data-anchor="#refs3"><sup> (3)</sup></a>. Bagaimana Anda mengonsumsi alkohol dan seberapa banyak dapat memengaruhi risiko kanker Anda <a href="#refs4" data-anchor="#refs4"><sup> (4)</sup></a>.</p> <p>Kajian peneliti menunjukkan bahwa konsumsi alkohol berlebihan merupakan faktor risiko untuk kanker mulut, tenggorokan, dan laring, atau kanker usus bagian atas <a href="#refs5" data-anchor="#refs5"><sup>(5, 6, 7)</sup></a>. Hal ini terutama terbukti pada orang-orang yang juga merokok atau mengonsumsi produk tembakau <a href="#refs7" data-anchor="#refs7"><sup>(7, 8, 9)</sup></a>. Risiko perkembangan kanker ini sama bagi laki-laki dan perempuan tanpa mempertimbangkan apakah mereka minum bir, wine, atau spirit <a href="#refs4" data-anchor="#refs4"><sup>(4, 7)</sup></a>.</p> <ul> <li>Orang-orang yang mengonsumsi alkohol berlebihan juga memiliki risiko lebih besar menderita kanker hati <a href="#refs5" data-anchor="#refs5">(5, 10)</a>. Sirosis hati, efek dari konsumsi alkohol berlebihan selama periode yang panjang, telah dihubungkan dengan perkembangan kanker hati. Faktor risiko mandiri lain termasuk mengisap tembakau <a href="#refs11" data-anchor="#refs11">(11)</a> dan obesitas <a href="#refs12" data-anchor="#refs12">(12, 13)</a>, serta infeksi hepatitis B <a href="#refs10" data-anchor="#refs10"><sup> (10)</sup></a>.</li> <li>Konsumsi alkohol berlebihan juga meningkatkan risiko kanker kolorektal <a href="#refs14" data-anchor="#refs14">(4, 5, 14)</a>. Beberapa kajian juga telah mencatat kenaikan risiko kanker kolorektal pada peminum beralkohol tingkat menengah <a href="#refs15" data-anchor="#refs15">(15, 16)</a>, terutama di kalangan laki-laki <a href="#refs7" data-anchor="#refs17"><sup> (17)</sup></a>.</li> <li>Kajian penelitian juga telah mendapati bahwa risiko kanker payudara dapat meningkat bagi perempuan bahkan jika mereka minum sewajarnya <a href="#refs5" data-anchor="#refs5"><sup> (5)</sup></a>. Dibandingkan dengan perempuan yang tidak mengonsumsi alkohol, <a href="/id-id/drinking-and-your-body/understanding-absolute-and-relative-risk-with-alcohol">risiko relatif</a> terkena kanker payudara meningkat seiring banyaknya ia mengonsumsi alkohol. Namun, menentukan kenaikan nyata risiko, juga punting untuk mengetahui risiko apa <a href="/id-id/drinking-and-your-body/understanding-absolute-and-relative-risk-with-alcohol">yang mutlak</a> atas perkembangan kanker payudara.</li> <li>Sebagai contoh, di UK, 116 dari 1000 perempuan lebih mungkin terdiagnosis kanker payudara sepanjang hidup mereka. Artinya seorang perempuan di UK memiliki risiko sebesar 11,6% terdiagnosis kanker payudara.</li> </ul> <p>Dibandingkan dengan yang tidak mengonsumsi alkohol sama sekali:</p> <ul> <li>Minum hingga 12,5 gram minuman beralkohol per hari - atau, menggunakan perhitungan Inggris Raya mengandung 8 g etanol, setara dengan satu setengah perhitungan UK - peningkatan risiko relatif kanker payudara bagi perempuan sebesar 4%. Hal ini berarti bahwa pada tingkat konsumsi alkohol ini, risiko mutlak meningkat dari 11,6% menjadi 12,1%.</li> <li>Minum antara 12,5 dan 50 gram minuman beralkohol per hari, atau antara satu setengah dan lebih dari enam perhitungan UK, meningkatkan risiko relatif kanker payudara bagi perempuan sebesar 23%. Dengan demikian, pada tingkat konsumsi alkohol ini, risiko mutlak meningkat dari 11,6% menjadi 14,3%.</li> <li>Minum hingga 50 gram minuman beralkohol per hari, atau lebih dari tiga setengah perhitungan UK - peningkatan risiko relatif kanker payudara bagi perempuan sebesar 61%. Pada tingkat konsumsi alkohol ini, risiko mutlak meningkat dari 11,6% menjadi 18,7%.<br /> Sumber: <a href="#refs5" data-anchor="#refs5"><sup> (5)</sup></a></li> </ul> <p>Hubungan antara konsumsi alkohol dan kanker payudara bergantung pada seberapa banyak minuman beralkohol yang diminum seorang perempuan, dan meningkat seiring dengan berlebihannya konsumsi alkohol. Risiko kanker payudara juga dipengaruhi oleh beberapa faktor, termasuk apakah ia obesitas, riwayat reproduksinya, apakah ia merokok, apakah ada kasus kanker payudara dalam keluarga dekatnya <a href="#refs2" data-anchor="#refs2"><sup>(2, 18, 19)</sup></a>.</p> <p>Faktor-faktor risiko kanker berinteraksi satu sama lain dan cara berlangsungnya berbeda bagi setiap orang <a href="#refs1" data-anchor="#refs1"><sup> (1)</sup></a>. Pendekatan baru untuk penanganan adalah peningkatan pemanfaatan perbedaan ini untuk menciptakan panduan yang dibuat khusus untuk setiap pasien <a href="#refs20" data-anchor="#refs20"><sup> (20)</sup></a>.</p> <p>Beberapa perubahan gaya hidup dapat membantu mengurangi risiko kanker, termasuk menjaga agar kebiasaan konsumsi alkohol sesuai dengan rekomendasi panduan <a href="/id-id/about-alcohol/what-are-drinking-guidelines-and-why-are-they-important">pemerintah</a>. Bagi beberapa orang, paling baik tidak mengonsumsi alkohol sama sekali. Namun demikian, untuk menyampaikan pertanyaan khusus Anda dan untuk mendapatkan saran terbaik bagi situasi Anda, Anda perlu berkonsultasi dengan tenaga kesehatan profesional untuk membantu Anda membuat keputusan yang sesuai dengan kebiasaan konsumsi alkohol Anda.</p> </div> </div> </section> <section class="module-link-box pt-0 pb-0"> <div class="container-fluid"> <div class="link-box column-start-1 column-end-13 "> <a class="link-wrapper d-flex" href='https://www.alodokter.com/kegunaan-alkohol-tak-sebanding-efek-negatifnya' target='_blank' title='Terbuka di jendela baru' data-linktype='external' aria-label="Untuk menemukan lebih banyak, kunjungi:"> <div class="link-icon"> <span class="external-link white"></span> </div> <div class="link-content"> <div class="link-text fw-800"> Untuk menemukan lebih banyak, kunjungi: </div> <span class=""> https://www.alodokter.com/ </span> <span class="small-link-icon external-link"> </span> </div> </a> </div> <div class="link-box column-start-1 column-end-13 "> <a class="link-wrapper d-flex" href='http://www.p2ptm.kemkes.go.id/search/alkohol' target='_blank' title='Terbuka di jendela baru' data-linktype='external' aria-label="Panduan konsumsi alkohol Kementerian Kesehatan"> <div class="link-icon"> <span class="external-link white"></span> </div> <div class="link-content"> <div class="link-text fw-800"> Panduan konsumsi alkohol Kementerian Kesehatan </div> <span class=""> http://www.p2ptm.kemkes.go.id/ </span> <span class="small-link-icon external-link"> </span> </div> </a> </div> </div> </section> <section class="accordion pb-0"> <div class="container-fluid"> <div class="accordion-item column-start-1 column-end-13 pt-20 pb-20"> <a href="javascript:void(0);" class="accordion-heading accordion-heading-js"> <span class="accordion-title fw-800">References</span> <span class="accordion-icon accordion-icon-js"> <svg width="20" height="20" viewBox="0 0 20 20" preserveAspectRatio="xMidYMid meet" fill="#2314a7" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" clip-rule="evenodd" d="M11 9H20V11H11V20H9V11H0V9H9V0H11V9Z"></path></svg> </span> </a> <div class="accordion-content accordion-content-js "><ol> <li><a href="https://www.cancer.gov/about-cancer/causes-prevention/risk" title="Terbuka di jendela baru" target="_blank" rel="noopener noreferrer" class="Article_typography_link__s55T6">National Cancer Institute (NCI). Risk factors for cancer. 2015; Available from: </a></li> <li>World Cancer Research Fund International (WCRFI), Diet, Nutrition, Physical Activity and Cancer: a Global Perspective. . 2018, WCRFI: London.</li> <li>Sasco, A.J., M.B. Secretan, and K. Straif, Tobacco smoking and cancer: a brief review of recent epidemiological evidence. Lung Cancer, 2004. 45 Suppl 2: p. S3-9.</li> <li> International Agency for Research on Cancer (IARC), Alcohol Consumption and Ethyl Carbamate, in IARC Monographs on the Identification of Carcinogenic Hazards to Humans. 2010, IARC: Lyon.</li> <li> Bagnardi, V., et al., Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis. Br J Cancer, 2015. 112(3): p. 580-93.</li> <li> de Menezes, R.F., A. Bergmann, and L.C. Thuler, Alcohol consumption and risk of cancer: a systematic literature review. Asian Pac J Cancer Prev, 2013. 14(9): p. 4965-72.</li> <li> Turati, F., W. Garavello, I. Tramacere, V. Bagnardi, M. Rota, L. Scotti, F. Islami, G. Corrao, P. Boffetta, C. La Vecchia and E. Negri (2010). "A meta-analysis of alcohol drinking and oral and pharyngeal cancers. Part 2: results by subsites." Oral Oncol 46(10): 720-726.</li> <li> Pelucchi, C., S. Gallus, W. Garavello, C. Bosetti and C. La Vecchia (2008). "Alcohol and tobacco use, and cancer risk for upper aerodigestive tract and liver." Eur J Cancer Prev 17(4): 340-344.</li> <li> Hashibe, M., et al., Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium. Cancer Epidemiol Biomarkers Prev, 2009. 18(2): p. 541-50.</li> <li> Zakhari, S., Chronic alcohol drinking: Liver and pancreatic cancer? Clin Res Hepatol Gastroenterol, 2015. 39 Suppl 1: p. S86-91.</li> <li> Baecker, A., X. Liu, C. La Vecchia and Z. F. Zhang (2018). "Worldwide incidence of hepatocellular carcinoma cases attributable to major risk factors." Eur J Cancer Prev 27(3): 205-212.</li> <li> Vanni, E. and E. Bugianesi (2014). "Obesity and liver cancer." Clin Liver Dis 18(1): 191-203.</li> <li> Marengo, A., C. Rosso and E. Bugianesi (2016). "Liver Cancer: Connections with Obesity, Fatty Liver, and Cirrhosis." Annu Rev Med 67: 103-117.</li> <li> Cai, S., et al., Alcohol drinking and the risk of colorectal cancer death: a meta-analysis. Eur J Cancer Prev, 2014. 23(6): p. 532-9.</li> <li> Vieira, A. R., L. Abar, D. S. M. Chan, S. Vingeliene, E. Polemiti, C. Stevens, D. Greenwood and T. Norat (2017). "Foods and beverages and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, an update of the evidence of the WCRF-AICR Continuous Update Project." Ann Oncol 28(8): 1788-1802.</li> <li> Rossi, M., M. Jahanzaib Anwar, A. Usman, A. Keshavarzian and F. Bishehsari (2018). "Colorectal Cancer and Alcohol Consumption-Populations to Molecules." Cancers (Basel) 10(2).</li> <li> Choi, Y. J., S. K. Myung and J. H. Lee (2018). "Light Alcohol Drinking and Risk of Cancer: A Meta-Analysis of Cohort Studies." Cancer Res Treat 50(2): 474-487.</li> <li> Rojas, K. and A. Stuckey, Breast Cancer Epidemiology and Risk Factors. Clin Obstet Gynecol, 2016. 59(4): p. 651-672.</li> <li> Tamimi, R.M., et al., Population Attributable Risk of Modifiable and Nonmodifiable Breast Cancer Risk Factors in Postmenopausal Breast Cancer. Am J Epidemiol, 2016. 184(12): p. 884-893.</li> <li> American Association for Cancer Research (AACR), AACR Cancer Progress Report 2019: Transforming Lives Through Innovative Cancer Science. 2019, AACR: Philadelphia, PA.</li> </ol></div> </div> </div> </section> <section id="module---two-column-text-with-link" class="two-column-text-with-link "> <div class="container-fluid"> <div class="test-and-help-block-wrapper column-start-1 column-end-13"> <div class="container-fluid p-0"> <div class="test-and-help-block column-start-1 column-end-13"> <div class="test-link-block-title column-start-1 column-end-13"> <h2 class="pt-40 mb-16">Apakah Anda khawatir tentang efek konsumsi alkohol?</h2> </div> <div class="test-link-block column-start-1 column-end-13"> <div> <p class="fw-300 mb-0">Entah itu diri Anda atau orang lain, gunakan penilaian mandiri konsumsi alkohol kami untuk memahami risikonya.</p> <div> <a class="d-flex justify-content-space-between align-items-center pt-20 pb-20 test-link" href=/id-id/audit data-linktype='internal' aria-label="Lakukan tes"> <span>Lakukan tes</span> <span class="cta cta-round"> </span> </a> </div> </div> <div class="help-section"> <p class="help-section-title mb-0 fw-300">Jika Anda atau orang yang Anda kenal mengonsumsi alkohol hingga menimbulkan masalah, daftar jaringan dukungan kami adalah awal yang bagus.</p> <div> <a class="d-flex justify-content-space-between align-items-center pt-20 pb-20 test-link help-link" href=/id-id/get-help data-linktype='internal'> <span>Cari bantuan sekarang</span> <span class="cta cta-round"> </span> </a></div> </div> </div> </div> </div> </div> </div> </section> <section class="article-link-wrapper"> <div class="container-fluid"> <div class="content-wrapper column-start-1 column-end-13"> <div class="main-title"> <h2 class="title m-0 fw-800">Lanjutkan membaca</h2> </div> <div class="article-items-wrapper"> <div> <a href="/id-id/drinking-and-your-body/how-does-drinking-affect-general-health" class="article-item-wrapper" aria-label="Bagaimana minum memengaruhi kesehatan umum?"> <div class="article-content"> <p class="article-category"> Minum dan tubuh Anda </p> <p class="article-title"> Bagaimana minum memengaruhi kesehatan umum? 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