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myometrial laceration</title> <meta name="description" content="Search results for: inner myometrial laceration"> <meta name="keywords" content="inner myometrial laceration"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button 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action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="inner myometrial laceration"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 24</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: inner myometrial laceration</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">24</span> Massive Intrapartum Hemorrhage Following by Inner Myometrial Laceration during a Vaginal Delivery: A Rare Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Bahareh%20Khakifirooz">Bahareh Khakifirooz</a>, <a href="https://publications.waset.org/abstracts/search?q=Arian%20Shojaei"> Arian Shojaei</a>, <a href="https://publications.waset.org/abstracts/search?q=Amirhossein%20Hajialigol"> Amirhossein Hajialigol</a>, <a href="https://publications.waset.org/abstracts/search?q=Bahare%20Abdolahi"> Bahare Abdolahi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Laceration of the inner layer of the myometrium can cause massive bleeding during and after childbirth, which can lead to the death of the mother if it is not diagnosed in time. We studied a rare case of massive intrapartum bleeding following myometrial laceration that was diagnosed correctly, and the patient survived with in-time treatments. The patient was a 26 years-old woman who was under observation for term pregnancy and complaint of rupture of membranes (ROM) and vaginal bleeding. Following the spontaneous course of labor and without receiving oxytocin, during the normal course of labor, she had an estimated total blood loss of 750 mL bleeding, which, despite the normal fetal heart rate and with the mother's indication for cesarean section, was transferred to the operating room and underwent cesarean section. During the cesarean section, the amniotic fluid was clear; after the removal of the placenta, severe and clear bleeding was flowing from the posterior wall of the uterus, which was caused by the laceration of the inner layer of the myometrium in the posterior wall of the lower segment of the uterus. The myometrial laceration was repaired with absorbable continuous locked sutures, and hemostasis was established, then, the patient used uterotonic drugs, and after monitoring, the patient was discharged from the hospital in good condition. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=intrapartum%20hemorrhage" title="intrapartum hemorrhage">intrapartum hemorrhage</a>, <a href="https://publications.waset.org/abstracts/search?q=inner%20myometrial%20laceration" title=" inner myometrial laceration"> inner myometrial laceration</a>, <a href="https://publications.waset.org/abstracts/search?q=labor" title=" labor"> labor</a>, <a href="https://publications.waset.org/abstracts/search?q=Increased%20intrauterine%20pressure" title=" Increased intrauterine pressure"> Increased intrauterine pressure</a> </p> <a href="https://publications.waset.org/abstracts/188869/massive-intrapartum-hemorrhage-following-by-inner-myometrial-laceration-during-a-vaginal-delivery-a-rare-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/188869.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">27</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">23</span> The Effect of Visfatin on Pregnant Mouse Myometrial Contractility in vitro</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Seham%20Alsaif">Seham Alsaif</a>, <a href="https://publications.waset.org/abstracts/search?q=Susan%20Wray"> Susan Wray</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Obesity is a worldwide disorder influencing women’s health and childbearing. There is a close relation between obesity and pregnancy related complications. Dyslipidemia and adipokine dysregulation are core environmental changes that may mechanistically link these complications with obesity in pregnant women. We have previously found that visfatin has a relaxant effect on mouse, rat and human myometrial contractility. We hypothesised that visfatin inhibits mouse myometrial contractility through the NAD+ pathway. This study was designed to examine the mechanism of action of visfatin on myometrial contractility. To examine the NAD+ pathway, FK866 which is a potent inhibitor of NAD+ biosynthesis was used. Methods: Myometrial strips from term pregnant mice were dissected, superfused with physiological saline and the effects of visfatin (10nM) on oxytocin-induced contractions (0.5nM) alone and after the infusion of FK866 (10uM) were studied. After regular contractions were established, contractility was examined for control (100%) and test response at 37 °C for 10 min each. Results: FK866 was found to inhibit the effect of visfatin on myometrial contractility (the AUC increased from 89±2% of control, P=0.0009 for visfatin alone to 97±4% of control, P>0.05 for visfatin combined with FK866, n=8). In conclusion, NAD+ pathway appears to be involved in the mechanism of action of visfatin on mouse myometrium. This could have a role in making new targets to prevent obesity-related complications. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=myometrium" title="myometrium">myometrium</a>, <a href="https://publications.waset.org/abstracts/search?q=obesity" title=" obesity"> obesity</a>, <a href="https://publications.waset.org/abstracts/search?q=oxytocin" title=" oxytocin"> oxytocin</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=visfatin" title=" visfatin"> visfatin</a> </p> <a href="https://publications.waset.org/abstracts/81512/the-effect-of-visfatin-on-pregnant-mouse-myometrial-contractility-in-vitro" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/81512.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">177</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">22</span> A Rare Neck Trauma by Bicycle Handlebar in Road Traffic Accident</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Parthasarathi%20Pramanik">Parthasarathi Pramanik</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Paediatric blunt abdominal trauma associated with superficial bruise, hematoma, or laceration and internal organ damage secondary to bicycle handlebar is widely documented in the literature. In this article, we have presented a case of bicycle handlebar inflicted fatal neck laceration in a road accident. The deceased sustained a horizontally placed laceration injury over the front and both sides of the middle third of neck (13 cm x 5-8 cm x 2-3.5 cm).The margins of the wound were irregular and focally abraded. The right corner of the injury was pointed whereas the left one was ended with a skin flap. Multiple graze abrasions, contusions and lacerations were found on different parts of body. Autopsy findings and other circumstantial evidences revealed that the victim died due to exsanguination because of severance of carotid artery and jugular vein of both sides. Analysis of the wound suggests the decease sustained the wound by the revolving bicycle handle bar while he had lost the balance. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=bicycle%20handle%20bar" title="bicycle handle bar">bicycle handle bar</a>, <a href="https://publications.waset.org/abstracts/search?q=neck%20injury" title=" neck injury"> neck injury</a>, <a href="https://publications.waset.org/abstracts/search?q=lacerated%20injury" title=" lacerated injury"> lacerated injury</a>, <a href="https://publications.waset.org/abstracts/search?q=road%20acident" title=" road acident"> road acident</a> </p> <a href="https://publications.waset.org/abstracts/54465/a-rare-neck-trauma-by-bicycle-handlebar-in-road-traffic-accident" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/54465.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">317</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">21</span> A Rare Case of Myometrial Ectopic</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Madeleine%20Cox">Madeleine Cox</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: Discussion of diagnosis and management options for myometrial ectopic pregnancy Case: A 30 yo G1P0 presented to the emergency department with vaginal bleeding for the last 4 days. She had a positive home urine pregnancy test, confirmed with a serum HCG. When she presented for an ultrasound, there was no intrauterine pregnancy, no evidence of adnexal pregnancy, however, the anterior myometrium of the uterus was noted to be markedly abnormal. When she presented to the emergency department of a busy tertiary hospital in Queensland, she had a small amount of vaginal bleeding, was anxious but well, observations normal. Repeat blood testes demonstrated a serum HCG of 9246 IU/L, haemoglobin of 143g/L. The patient had an interesting history of a right oophorectomy and open myomectomy in another country. A repeat ultrasound again showed an abnormality within the myometrium of the uterus, which was initially reported as concerning for an AVM, or potentially invasive gestational trophoblastic disease. An MRI was organised 2 days later, which demonstrated a intramural/subserosal irregularity in the right lateral body measuring 35x38x42mm with peripheral enhancement and central cystic components, favouring a myometrial ectopic most likely at the site of previous myomectomy. Alternative diagnosis of AVM, GTD were considered less likely. After discussion with the patient, IV methotrexate was administered as an in patient 4 days after her initial presentation to emergency. After this, her HCG fell to 1236 IU/L on day 6 post treatment. Weekly reviews showed stable ultrasound appearances with a steadily dropping HCG level. A repeat MRI was performed 3 weeks after methotrexate administration which confirmed involution of the myometrial ectopic, however, showed ongoing progression of vascularity surrounding the site. Despite resolution of HCG, the patient persisted to have ongoing bleeding associated with this and went to have uterine artery embolisation. Follow up ultrasound showed resolution of abnormal vascularity and negative HCG levels. Conclusion: Myometrial ectopic pregnancies are a rare occurrence and require a multidisciplinary approach to achieve timely management for these patients. This patient was in a very well resourced setting with excellent access to Interventional Radiology and specialist Radiologists who could work together with the Obstetrics, Gynaecology, and Maternal Fetal Medicine team to provide multiple options of management which preserved her fertility. This case has a very good outcome, with the patient being referred back to our service 12 months later with an early intrauterine pregnancy. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=ectopic" title="ectopic">ectopic</a>, <a href="https://publications.waset.org/abstracts/search?q=pregnancy" title=" pregnancy"> pregnancy</a>, <a href="https://publications.waset.org/abstracts/search?q=miscarriage" title=" miscarriage"> miscarriage</a>, <a href="https://publications.waset.org/abstracts/search?q=gynaecology" title=" gynaecology"> gynaecology</a> </p> <a href="https://publications.waset.org/abstracts/148755/a-rare-case-of-myometrial-ectopic" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/148755.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">133</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">20</span> Clinical and Radiological Features of Adenomyosis and Its Histopathological Correlation </h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Surabhi%20Agrawal%20Kohli">Surabhi Agrawal Kohli</a>, <a href="https://publications.waset.org/abstracts/search?q=Sunita%20Gupta"> Sunita Gupta</a>, <a href="https://publications.waset.org/abstracts/search?q=Esha%20Khanuja"> Esha Khanuja</a>, <a href="https://publications.waset.org/abstracts/search?q=Parul%20Garg"> Parul Garg</a>, <a href="https://publications.waset.org/abstracts/search?q=P.%20Gupta"> P. Gupta </a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Adenomyosis is a common gynaecological condition that affects the menstruating women. Uterine enlargement, dysmenorrhoea, and menorrhagia are regarded as the cardinal clinical symptoms of adenomyosis. Classically it was thought, compared with ultrasonography, when adenomyosis is suspected, MRI enables more accurate diagnosis of the disease. Materials and Methods: 172 subjects were enrolled after an informed consent that had complaints of HMB, dyspareunia, dysmenorrhea, and chronic pelvic pain. Detailed history of the enrolled subjects was taken, followed by a clinical examination. These patients were then subjected to TVS where myometrial echo texture, presence of myometrial cysts, blurring of endomyometrial junction was noted. MRI was followed which noted the presence of junctional zone thickness and myometrial cysts. After hysterectomy, histopathological diagnosis was obtained. Results: 78 participants were analysed. The mean age was 44.2 years. 43.5% had parity of 4 or more. heavy menstrual bleeding (HMB) was present in 97.8% and dysmenorrhea in 93.48 % of HPE positive patient. Transvaginal sonography (TVS) and MRI had a sensitivity of 89.13% and 80.43%, specificity of 90.62% and 84.37%, positive likelihood ratio of 9.51 and 5.15, negative likelihood ratio of 0.12 and 0.23, positive predictive value of 93.18% and 88.1%, negative predictive value of 85.29% and 75% and a diagnostic accuracy of 89.74% and 82.5%. Comparison of sensitivity (p=0.289) and specificity (p=0.625) showed no statistically significant difference between TVS and MRI. Conclusion: Prevalence of 30.23%. HMB with dysmenorrhoea and chronic pelvic pain helps in diagnosis. TVS (Endomyometrial junction blurring) is both sensitive and specific in diagnosing adenomyosis without need for additional diagnostic tool. Both TVS and MRI are equally efficient, however because of certain additional advantages of TVS over MRI, it may be used as the first choice of imaging. MRI may be used additionally in difficult cases as well as in patients with existing co-pathologies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adenomyosis" title="adenomyosis">adenomyosis</a>, <a href="https://publications.waset.org/abstracts/search?q=heavy%20menstrual%20bleeding" title=" heavy menstrual bleeding"> heavy menstrual bleeding</a>, <a href="https://publications.waset.org/abstracts/search?q=MRI" title=" MRI"> MRI</a>, <a href="https://publications.waset.org/abstracts/search?q=TVS" title=" TVS"> TVS</a> </p> <a href="https://publications.waset.org/abstracts/51885/clinical-and-radiological-features-of-adenomyosis-and-its-histopathological-correlation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/51885.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">498</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">19</span> Insight into Figo Sub-classification System of Uterine Fibroids and Its Clinical Importance as Well as MR Imaging Appearances of Atypical Fibroids</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Madhuri%20S.%20Ghate">Madhuri S. Ghate</a>, <a href="https://publications.waset.org/abstracts/search?q=Rahul%20P.%20Chavhan"> Rahul P. Chavhan</a>, <a href="https://publications.waset.org/abstracts/search?q=Shriya%20S.%20Nahar"> Shriya S. Nahar</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Learning objective: •To describe Magnetic Resonance Imaging (MRI) imaging appearances of typical and atypical uterine fibroids with emphasis on differentiating it from other similar conditions. •To classify uterine fibroids according to International Federation of Gynecology and Obstetrics (FIGO) Sub-classifications system and emphasis on its clinical significance. •To show cases with atypical imaging appearances atypical fibroids Material and methods: MRI of Pelvis had been performed in symptomatic women of child bearing age group on 1.5T and 3T MRI using T1, T2, STIR, FAT SAT, DWI sequences. Contrast was administered when degeneration was suspected. Imaging appearances of Atypical fibroids and various degenerations in fibroids were studied. Fibroids were classified using FIGO Sub-classification system. Its impact on surgical decision making and clinical outcome were also studied qualitatively. Results: Intramural fibroids were most common (14 patients), subserosal 7 patients, submucosal 5 patients . 6 patients were having multiple fibroids. 7 were having atypical fibroids. (1 hyaline degeneration, 1 cystic degeneration, 1 fatty, 1 necrosis and hemorrhage, 1 red degeneration, 1 calcification, 1 unusual large bilobed growth). Fibroids were classified using FIGO system. In uterus conservative surgeries, the lesser was the degree of myometrial invasion of fibroid, better was the fertility outcome. Conclusion: Relationship of fibroid with mucosal and serosal layers is important in the management of symptomatic fibroid cases. Risk to fertility involved in uterus conservative surgeries in women of child bearing age group depends on the extent of myometrial invasion of fibroids. FIGO system provides better insight into the degree of myometrial invasion. Knowledge about the atypical appearances of fibroids is important to avoid diagnostic confusion and untoward treatment. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=degeneration" title="degeneration">degeneration</a>, <a href="https://publications.waset.org/abstracts/search?q=FIGO%20sub-classification" title=" FIGO sub-classification"> FIGO sub-classification</a>, <a href="https://publications.waset.org/abstracts/search?q=MRI%20pelvis" title=" MRI pelvis"> MRI pelvis</a>, <a href="https://publications.waset.org/abstracts/search?q=uterine%20fibroids" title=" uterine fibroids"> uterine fibroids</a> </p> <a href="https://publications.waset.org/abstracts/161429/insight-into-figo-sub-classification-system-of-uterine-fibroids-and-its-clinical-importance-as-well-as-mr-imaging-appearances-of-atypical-fibroids" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161429.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">92</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">18</span> Death Due to Ulnar Artery Injury by Glassdoor: A Case Report</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ashok%20Kumar%20Rastogi">Ashok Kumar Rastogi</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Glass is a material commonly used for Glassdoor, glass bottles, cookware, and containers. It can be harmful, as it is a hard and blunt object. Glass has been associated with severe injury and is a common cause of injuries warranting hospital visits to the emergency department (ED). These injuries can be accidental or intentionally inflicted. Broken glass injuries can be severe, even deadly. If broken glass shards fall out on your arm, it may cause fatal injuries. Case history: A 20-year-old male dead body was found aside the road, police informed, and a video recording ceased during an investigation. In the video recording, the person was in a drunken state (unable to walk and disoriented), wandering in the residential area road. He saw a barber shop, the shop door made of Glass. Suddenly, he hit the Glassdoor with his right hand forcefully. The Glassdoor broke into multiple pieces, and multiple injuries were seen over the right hand. Observations: Multiple small and large lacerations were seen over the right anterior part of the elbow. The main injury looked like an incised wound caused by a hard and sharp object. The main injury was noted as a laceration of size 13 x 06 cm bone deep, placed obliquely over the anteromedial aspect of the right elbow joint, its medial end at medial end of elbow joint while its anterior end was 04 cm below the elbow joint with laceration of underline brachialis muscles and complete transaction of ulnar artery and vein, skin margins looking sharply cut with irregular margins with tiny cuts at the medial lower border of laceration. Injuries were antemortem and fresh in nature, caused by hard and blunt objects but looking like hard and sharp objects. All organs were found pale, and the cause of death was shock and hemorrhage because of ulnar vessel injury. Conclusion: The findings of this case report highlight the potentially lethal consequences of glass injuries, especially those involving Glassdoors. The study underscores the importance of accurate interpretation and identification of wounds caused by Glass, as they may resemble injuries caused by other objects. It emphasizes the challenges faced by autopsy surgeons when determining the cause and manner of death in cases where visual evidence of injury is absent or when the weapon is not recovered. Ultimately, this case report serves as a reminder of the potential dangers posed by Glass and the importance of comprehensive forensic examinations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=glassdoor" title="glassdoor">glassdoor</a>, <a href="https://publications.waset.org/abstracts/search?q=incised" title=" incised"> incised</a>, <a href="https://publications.waset.org/abstracts/search?q=wound" title=" wound"> wound</a>, <a href="https://publications.waset.org/abstracts/search?q=laceration" title=" laceration"> laceration</a>, <a href="https://publications.waset.org/abstracts/search?q=autopsy" title=" autopsy"> autopsy</a> </p> <a href="https://publications.waset.org/abstracts/174242/death-due-to-ulnar-artery-injury-by-glassdoor-a-case-report" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/174242.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">77</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">17</span> A Study of the Atlantoaxial Fracture or Dislocation in Motorcyclists with Helmet Accidents</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Shao-Huang%20Wu">Shao-Huang Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=Ai-Yun%20Wu"> Ai-Yun Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=Meng-Chen%20Wu"> Meng-Chen Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=Chun-Liang%20Wu"> Chun-Liang Wu</a>, <a href="https://publications.waset.org/abstracts/search?q=Kai-Ping%20Shaw"> Kai-Ping Shaw</a>, <a href="https://publications.waset.org/abstracts/search?q=Hsiao-Ting%20Chen"> Hsiao-Ting Chen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Objective: To analyze the forensic autopsy data of known passengers and compare it with the National database of the autopsy report in 2017, and obtain the special patterned injuries, which can be used as the reference for the reconstruction of hit-and-run motor vehicle accidents. Methods: Analyze the items of the Motor Vehicle Accident Report, including Date of accident, Time occurred, Day, Acc. severity, Acc. Location, Acc. Class, Collision with Vehicle, Motorcyclists Codes, Safety equipment use, etc. Analyzed the items of the Autopsy Report included, including General Description, Clothing and Valuables, External Examination, Head and Neck Trauma, Trunk Trauma, Other Injuries, Internal Examination, Associated Items, Autopsy Determinations, etc. Materials: Case 1. The process of injury formation: the car was chased forward and collided with the scooter. The passenger wearing the helmet fell to the ground. The helmet crashed under the bottom of the sedan, and the bottom of the sedan was raised. Additionally, the sedan was hit on the left by the other sedan behind, resulting in the front sedan turning 180 degrees on the spot. The passenger’s head was rotated, and the cervical spine was fractured. Injuries: 1. Fracture of atlantoaxial joint 2. Fracture of the left clavicle, scapula, and proximal humerus 3. Fracture of the 1-10 left ribs and 2-7 right ribs with lung contusion and hemothorax 4. Fracture of the transverse process of 2-5 lumbar vertebras 5. Comminuted fracture of the right femur 6. Suspected subarachnoid space and subdural hemorrhage 7. Laceration of the spleen. Case 2. The process of injury formation: The motorcyclist wearing the helmet fell to the left by himself, and his chest was crushed by the car going straight. Only his upper body was under the car and the helmet finally fell off. Injuries: 1. Dislocation of atlantoaxial joint 2. Laceration on the left posterior occipital 3. Laceration on the left frontal 4. Laceration on the left side of the chin 5. Strip bruising on the anterior neck 6. Open rib fracture of the right chest wall 7. Comminuted fracture of both 1-12 ribs 8. Fracture of the sternum 9. Rupture of the left lung 10. Rupture of the left and right atria, heart tip and several large vessels 11. The aortic root is nearly transected 12. Severe rupture of the liver. Results: The common features of the two cases were the fracture or dislocation of the atlantoaxial joint and both helmets that were crashed. There were no atlantoaxial fractures or dislocations in 27 pedestrians (without wearing a helmet) versus motor vehicle accidents in 2017 the National database of an autopsy report, but there were two atlantoaxial fracture or dislocation cases in the database, both of which were cases of falling from height. Conclusion: The cervical spine fracture injury of the motorcyclist, who was wearing a helmet, is very likely to be a patterned injury caused by his/her fall and rollover under the sedan. It could provide a reference for forensic peers. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=patterned%20injuries" title="patterned injuries">patterned injuries</a>, <a href="https://publications.waset.org/abstracts/search?q=atlantoaxial%20fracture%20or%20dislocation" title=" atlantoaxial fracture or dislocation"> atlantoaxial fracture or dislocation</a>, <a href="https://publications.waset.org/abstracts/search?q=accident%20reconstruction" title=" accident reconstruction"> accident reconstruction</a>, <a href="https://publications.waset.org/abstracts/search?q=motorcycle%20accident%20with%20helmet" title=" motorcycle accident with helmet"> motorcycle accident with helmet</a>, <a href="https://publications.waset.org/abstracts/search?q=forensic%20autopsy%20data" title=" forensic autopsy data"> forensic autopsy data</a> </p> <a href="https://publications.waset.org/abstracts/161182/a-study-of-the-atlantoaxial-fracture-or-dislocation-in-motorcyclists-with-helmet-accidents" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/161182.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">93</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">16</span> Trial of Resorbable versus Non-Resorbable Sutures for Traumatic Lacerations of the Face: A Demonstration of Maxillo-Facial Trainee Led Research</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=R.%20Botrugno">R. Botrugno</a>, <a href="https://publications.waset.org/abstracts/search?q=S%20Basyuni"> S Basyuni</a>, <a href="https://publications.waset.org/abstracts/search?q=G.%20Nugent"> G. Nugent</a>, <a href="https://publications.waset.org/abstracts/search?q=I.%20Jenkyn"> I. Jenkyn</a>, <a href="https://publications.waset.org/abstracts/search?q=A.%20Ferro"> A. Ferro</a>, <a href="https://publications.waset.org/abstracts/search?q=H.%20Bennett"> H. Bennett</a>, <a href="https://publications.waset.org/abstracts/search?q=C.%20Hjalmarsson"> C. Hjalmarsson</a>, <a href="https://publications.waset.org/abstracts/search?q=J.%20Chu"> J. Chu</a>, <a href="https://publications.waset.org/abstracts/search?q=V.%20Santhanam"> V. Santhanam</a> </p> <p class="card-text"><strong>Abstract:</strong></p> This trainee led randomised controlled trial (RCT) aims to assess various outcomes for resorbable versus non-resorbable sutures for traumatic lacerations to the face. Within this trial of resorbable versus non-resorbable sutures for traumatic lacerations of the face (TORNFace), patient recruitment was facilitated by trainees who were employed at an NHS University Teaching Hospital in the United Kingdom. The trainees received appropriate training prior to recruiting patients for the trial. This included the completion of a national research e-learning module and face-to-face training that was provided locally. The locally delivered training provided an understanding of the eligibility criteria for the trial and the consent process. Existing trainee skills were utilised involving clinical photography to record baseline data and delivering the intervention based on the treatment arm selected. Eligible patients who required primary closure of traumatic lacerations of the face were randomised into one of two treatment arms. These comprised of resorbable (vicryl rapide) or non-resorbable sutures (ethilon). Primarily the cosmetic outcome was assessed. Secondary outcomes included: complications rates, health care economics, and patient-reported outcomes. Remote follow-up of recruited patients utilised photographs of the facial laceration which had received the intervention. These took place at 1 week, 3 months and 6 months post-intervention. This study aims to demonstrate an example of trainee-led research within the specialty of oral and maxillofacial surgery. The available data for the randomised controlled trial will also be presented. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=laceration" title="laceration">laceration</a>, <a href="https://publications.waset.org/abstracts/search?q=suture" title=" suture"> suture</a>, <a href="https://publications.waset.org/abstracts/search?q=trauma" title=" trauma"> trauma</a>, <a href="https://publications.waset.org/abstracts/search?q=trial" title=" trial"> trial</a> </p> <a href="https://publications.waset.org/abstracts/152129/trial-of-resorbable-versus-non-resorbable-sutures-for-traumatic-lacerations-of-the-face-a-demonstration-of-maxillo-facial-trainee-led-research" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/152129.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">137</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">15</span> Single Centre Retrospective Analysis of MR Imaging in Placenta Accreta Spectrum Disorder with Histopathological Correlation</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Frank%20Dorrian">Frank Dorrian</a>, <a href="https://publications.waset.org/abstracts/search?q=Aniket%20Adhikari"> Aniket Adhikari</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The placenta accreta spectrum (PAS), which includes placenta accreta, increta, and percreta, is characterized by the abnormal implantation of placental chorionic villi beyond the decidua basalis. Key risk factors include placenta previa, prior cesarean sections, advanced maternal age, uterine surgeries, multiparity, pelvic radiation, and in vitro fertilization (IVF). The incidence of PAS has increased tenfold over the past 50 years, largely due to rising cesarean rates. PAS is associated with significant peripartum and postpartum hemorrhage. Magnetic resonance imaging (MRI) and ultrasound assist in the evaluation of PAS, enabling a multidisciplinary approach to mitigate morbidity and mortality. This study retrospectively analyzed PAS cases at Royal Prince Alfred Hospital, Sydney, Australia. Using the SAR-ESUR joint consensus statement, seven imaging signs were reassessed for their sensitivity and specificity in predicting PAS, with histopathological correlation. The standardized MRI protocols for PAS at the institution were also reviewed. Data were collected from the picture archiving and communication system (PACS) records from 2010 to July 2024, focusing on cases where MR imaging and confirmed histopathology or operative notes were available. This single-center, observational study provides insights into the reliability of MRI for PAS detection and the optimization of imaging protocols for accurate diagnosis. The findings demonstrate that intraplacental dark bands serve as highly sensitive markers for diagnosing PAS, achieving sensitivities of 88.9%, 85.7%, and 100% for placenta accreta, increta, and percreta, respectively, with a combined specificity of 42.9%. Sensitivity for abnormal vascularization was lower (33.3%, 28.6%, and 50%), with a specificity of 57.1%. The placenta bulge exhibited sensitivities of 55.5%, 57.1%, and 100%, with a specificity of 57.1%. Loss of the T2 hypointense interface had sensitivities of 66.6%, 85.7%, and 100%, with 42.9% specificity. Myometrial thinning showed high sensitivity across PAS conditions (88.9%, 71.4%, and 100%) and a specificity of 57.1%. Bladder wall thinning was sensitive only for placenta percreta (50%) but had a specificity of 100%. Focal exophytic mass displayed variable sensitivity (22.9%, 42.9%, and 100%) with a specificity of 85.7%. These results highlight the diagnostic variability among markers, with intraplacental dark bands and myometrial thinning being useful in detecting abnormal placentation, though they lack high specificity. The literature and the results of our study highlight that while no single feature can definitively diagnose PAS, the presence of multiple features -especially when combined with elevated clinical risk- significantly increases the likelihood of an underlying PAS. A thorough understanding of the range of MRI findings associated with PAS, along with awareness of the clinical significance of each sign, helps the radiologist more accurately diagnose the condition and assist in surgical planning, ultimately improving patient care. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=placenta" title="placenta">placenta</a>, <a href="https://publications.waset.org/abstracts/search?q=accreta" title=" accreta"> accreta</a>, <a href="https://publications.waset.org/abstracts/search?q=spectrum" title=" spectrum"> spectrum</a>, <a href="https://publications.waset.org/abstracts/search?q=MRI" title=" MRI"> MRI</a> </p> <a href="https://publications.waset.org/abstracts/194620/single-centre-retrospective-analysis-of-mr-imaging-in-placenta-accreta-spectrum-disorder-with-histopathological-correlation" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194620.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">8</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">14</span> Uncommon Case of Falx Subdural Hematoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Thu%20Nguyen">Thu Nguyen</a>, <a href="https://publications.waset.org/abstracts/search?q=Jane%20Daugherty-Luck"> Jane Daugherty-Luck</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Falx subdural hematoma is a life-threatening condition associated with high mortality. We present a patient case who had fallen with no head injury or loss of conspicuousness. She had tenderness along cervical and thoracic lumbar spine. CT head revealed falx subdural hematoma. The patient was managed medically. The pathophysiology of falx subdural hematoma is linked to laceration of bridging veins provoked by frontal or occipital impact. Posttraumatic subdural hematoma is commonly caused by inertia instead of facture or cerebral contusion resulting from direct impact. The theory is consistent with the lack of fracture in most cases in the literature. Our patient had neither contusion nor fracture. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=falx%20subdural%20hematoma" title="falx subdural hematoma">falx subdural hematoma</a>, <a href="https://publications.waset.org/abstracts/search?q=traumatic%20head%20injury" title=" traumatic head injury"> traumatic head injury</a>, <a href="https://publications.waset.org/abstracts/search?q=CT%20head%20scan" title=" CT head scan"> CT head scan</a>, <a href="https://publications.waset.org/abstracts/search?q=bridging%20veins" title=" bridging veins"> bridging veins</a>, <a href="https://publications.waset.org/abstracts/search?q=inertia" title=" inertia"> inertia</a> </p> <a href="https://publications.waset.org/abstracts/135186/uncommon-case-of-falx-subdural-hematoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/135186.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">140</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">13</span> Visual and Clinical Outcome in Patients with Corneal Lacerations</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Avantika%20Verma">Avantika Verma</a> </p> <p class="card-text"><strong>Abstract:</strong></p> In industrialized nations, corneal lacerations are one of the most common reason for hospitalization. This study was designed to study visual and clinical outcome in patients presenting with full thickness corneal lacerations in Indian population and to ascertain the impact of various preoperative and operative factors influencing prognosis after repair of corneal lacerations. Males in third decade with injuries at work with metallic objects were common. Lens damage, hyphema, vitreous hemorrhage, retinal detachment and endophthalmitis were seen. All the patients underwent primary repair within first 24 hours of presentation. At 3 months, 74.3% had a good visual outcome. About 5.7% of patients had no perception of light.In conclusion, various demographic and preoperative factors like age, time of presentation, vision at presentation, length of corneal wound, involvement of visual axis, associated ocular features like hyphaema, lenticular changes, vitreous haemorrhage and retinal detachment are significant prognostic indicators for final visual outcome. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=corneal%20laceration" title="corneal laceration">corneal laceration</a>, <a href="https://publications.waset.org/abstracts/search?q=corneal%20wound%20repair" title=" corneal wound repair"> corneal wound repair</a>, <a href="https://publications.waset.org/abstracts/search?q=injury" title=" injury"> injury</a>, <a href="https://publications.waset.org/abstracts/search?q=visual%20outcome" title=" visual outcome"> visual outcome</a> </p> <a href="https://publications.waset.org/abstracts/70121/visual-and-clinical-outcome-in-patients-with-corneal-lacerations" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/70121.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">357</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">12</span> Lymphatic Microvessel Density as a Prognostic Factor in Endometrial Carcinoma</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Noha%20E.%20Hassan">Noha E. Hassan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Little is known regarding the influence of lymphatic microvessel density (LMVD) on prognosis in endometrial cancer. Prospective study was done in tertiary education and research hospital (Shatby Alexandria university hospital) on sixty patients presented with endometrial carcinoma underwent complete surgical staging. Our aim was to assess the intratumoral and peritumoral Lymphatic microvessel density (LMVD) of endometrial carcinomas identified by immunohistochemical staining using an antibody against podoplanin and to investigate their association with classical clinicopathological factors and prognosis. The result shows that high LMVD was associated with endometroid type of tumors, lesser myometrial, adnexal, cervical and peritoneal infiltration, lower tumor grade and stage and lesser recurrent cases. There is lower lymph node involvement among cases with high intratumoral LMVD and cases of high peritumoral LMVD; that reach statistical significance only among cases of high intratumoral LMVD. No association was seen between LMVD and lymphovascular space invasion. On the other hand, low LMVD was associated with poor outcome. Finally, we can conclude that increased LMVD is associated with favorable prognosis in endometrial cancer patients. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=endometrial%20carcinoma" title="endometrial carcinoma">endometrial carcinoma</a>, <a href="https://publications.waset.org/abstracts/search?q=lymphatic%20microvessel" title=" lymphatic microvessel"> lymphatic microvessel</a>, <a href="https://publications.waset.org/abstracts/search?q=microvessel%20density" title=" microvessel density"> microvessel density</a>, <a href="https://publications.waset.org/abstracts/search?q=prognosis" title=" prognosis"> prognosis</a> </p> <a href="https://publications.waset.org/abstracts/108777/lymphatic-microvessel-density-as-a-prognostic-factor-in-endometrial-carcinoma" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/108777.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">141</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">11</span> Anatomical Features of Internal Pudendal Artery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Adel%20Yasky">Adel Yasky</a>, <a href="https://publications.waset.org/abstracts/search?q=Waseem%20Al-Talalwah"> Waseem Al-Talalwah</a>, <a href="https://publications.waset.org/abstracts/search?q=Shorok%20Al%20Dorazi"> Shorok Al Dorazi</a>, <a href="https://publications.waset.org/abstracts/search?q=Roger%20Soames"> Roger Soames</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The internal pudendal artery is a standard branch of the anterior division of the internal iliac artery. The current study includes 41 cadavers to investigate the origin and branches of the internal pudendal artery and its clinical significances. The internal pudendal artery arose directly from the anterior division of the internal iliac artery in 48.3% while it arose indirectly in 48.5%. However, the internal pudendal artery arose from the posterior division of internal iliac artery in 1.6%. Moreover, it arose internal iliac artery bifurcation site in 1.6%. Further, the internal pudendal artery supplied the urinary bladder in 17.1%. Also, the internal pudendal artery supplied the rectum 33.5% respectively. It gave uterine and vaginal arteries in 9.4% and 7.8% respectively. Finally, it supplied the sciatic nerve via giving lateral sacral branch in 1.6%. Internists, surgeons and radiologists have to be aware of the variability to decrease iatrogenic injury. Therefore, unnecessary proximal ligation should be avoided at the site of indirect origin of the internal pudendal artery to prevent sciatic neuropathy. Further, intrapelvic bleeding as result of laceration of internal pudendal branches during hysterectomy, prostatectomy or proctectomy should be expected. Therefore, this study increases the awareness of surgeons leading to minimize iatrogenic faults, <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=internal%20pudendal%20artery" title="internal pudendal artery">internal pudendal artery</a>, <a href="https://publications.waset.org/abstracts/search?q=inferior%20gluteal%20artery" title=" inferior gluteal artery"> inferior gluteal artery</a>, <a href="https://publications.waset.org/abstracts/search?q=superior%20gluteal%20artery" title=" superior gluteal artery"> superior gluteal artery</a>, <a href="https://publications.waset.org/abstracts/search?q=internal%20iliac%20artery" title=" internal iliac artery"> internal iliac artery</a>, <a href="https://publications.waset.org/abstracts/search?q=impotence" title=" impotence"> impotence</a>, <a href="https://publications.waset.org/abstracts/search?q=decreased%20libido" title=" decreased libido"> decreased libido</a> </p> <a href="https://publications.waset.org/abstracts/30963/anatomical-features-of-internal-pudendal-artery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/30963.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">356</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">10</span> Risk Factor of Anal Incontinence among Women in Makassar</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Azizah%20Nurdin">Azizah Nurdin</a>, <a href="https://publications.waset.org/abstracts/search?q=Trika%20Irianta"> Trika Irianta</a>, <a href="https://publications.waset.org/abstracts/search?q=Mardiah%20Tahir"> Mardiah Tahir</a>, <a href="https://publications.waset.org/abstracts/search?q=Maisuri%20T.%20Chalid"> Maisuri T. Chalid</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Studies of anal incontinence in the general population are rare however its financial healthcare cost is significant. Women attended Hasanuddin University Teaching Hospital and its networking in Makassar, Indonesia was surveyed between February to April 2015 about their obstetrical and gynecological history. Aims: To establish obstetrical risk factor of anal incontinence among women in Makassar. Methods: In a cross sectional face to face interview study, 135 women aged 30 years or more were selected randomly. Participants were asked to complete an anal incontinence questionnaire. Results: From a total sample of 135 respondents, 42,2 % reported has flatulence incontinence. Parity, history of anal sphincter laceration, history of having large baby, history of assisted vaginal delivery were shown have no significant association with anal incontinence, while history of episiotomy was shown have a significant association with anal incontinence (p value < 0.05). The risk of flatulence incontinence was higher among women with history of episiotomy (OR : 2,85, 95 % CI = 1,58- 5,13) Conclusions: This study has confirmed that fecal incontinence is a fairly common symptom. Flatulence incontinence is the most frequent even. An obstetrical factor like episiotomy is one of risk factor that could be avoided in order to prevent anal incontinence. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=anal%20incontinence" title="anal incontinence">anal incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=flatulence%20incontinence" title=" flatulence incontinence"> flatulence incontinence</a>, <a href="https://publications.waset.org/abstracts/search?q=obstetrical%20risk%20factor" title=" obstetrical risk factor"> obstetrical risk factor</a>, <a href="https://publications.waset.org/abstracts/search?q=women" title=" women"> women</a> </p> <a href="https://publications.waset.org/abstracts/32498/risk-factor-of-anal-incontinence-among-women-in-makassar" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/32498.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">318</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">9</span> Sensitivity and Specificity of Clinical Testing for Digital Nerve Injury</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Guy%20Rubin">Guy Rubin</a>, <a href="https://publications.waset.org/abstracts/search?q=Ravit%20Shay"> Ravit Shay</a>, <a href="https://publications.waset.org/abstracts/search?q=Nimrod%20Rozen"> Nimrod Rozen</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The accuracy of a diagnostic test used to classify a patient as having disease or being disease-free is a valuable piece of information to be used by the physician when making treatment decisions. Finger laceration, suspected to have nerve injury is a challenging decision for the treating surgeon. The purpose of this study was to evaluate the sensitivity, specificity and predictive values of six clinical tests in the diagnosis of digital nerve injury. The six clinical tests included light touch, pin prick, static and dynamic 2-point discrimination, Semmes Weinstein monofilament and wrinkle test. Data comparing pre-surgery examination with post-surgery results of 42 patients with 52 digital nerve injury was evaluated. The subjective examinations, light touch, pin prick, static and dynamic 2-point discrimination and Semmes-Weinstein monofilament were not sensitive (57.6, 69.7, 42.4, 40 and 66.8% respectively) and specific (36.8, 36.8, 47.4, 42.1 and 31.6% respectively). Wrinkle test, the only objective examination, was the most sensitive (78.1%) and specific (55.6%). This result gives no pre-operative examination the ability to predict the result of explorative surgery. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=digital%20nerve" title="digital nerve">digital nerve</a>, <a href="https://publications.waset.org/abstracts/search?q=injury" title=" injury"> injury</a>, <a href="https://publications.waset.org/abstracts/search?q=nerve%20examination" title=" nerve examination"> nerve examination</a>, <a href="https://publications.waset.org/abstracts/search?q=Semmes-Weinstein%20monofilamen" title=" Semmes-Weinstein monofilamen"> Semmes-Weinstein monofilamen</a>, <a href="https://publications.waset.org/abstracts/search?q=sensitivity" title=" sensitivity"> sensitivity</a>, <a href="https://publications.waset.org/abstracts/search?q=specificity" title=" specificity"> specificity</a>, <a href="https://publications.waset.org/abstracts/search?q=two%20point%20discrimination" title=" two point discrimination"> two point discrimination</a>, <a href="https://publications.waset.org/abstracts/search?q=wrinkle%20test" title=" wrinkle test"> wrinkle test</a> </p> <a href="https://publications.waset.org/abstracts/74474/sensitivity-and-specificity-of-clinical-testing-for-digital-nerve-injury" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/74474.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">344</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">8</span> The Origin Variability of the Obturator Artery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Halimah%20Al%20Hifzi">Halimah Al Hifzi</a>, <a href="https://publications.waset.org/abstracts/search?q=Waseem%20Al-Talalwah"> Waseem Al-Talalwah</a>, <a href="https://publications.waset.org/abstracts/search?q=Shorok%20Al%20Dorazi"> Shorok Al Dorazi</a>, <a href="https://publications.waset.org/abstracts/search?q=Hassan%20Al%20Mousa"> Hassan Al Mousa</a>, <a href="https://publications.waset.org/abstracts/search?q=Zainab%20Al-Hashim"> Zainab Al-Hashim</a>, <a href="https://publications.waset.org/abstracts/search?q=Roger%20Soames"> Roger Soames</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The obturator artery is one branches of anterior division of the internal iliac artery. It passes on the lateral wall of pelvis to escape into thigh region via obturator foremen. Based on previous research studies, it found to be extremely variable in origin and course. It may arise from internal or external iliac artery. The current study includes 82 dissected specimens to investigate the origin of the obturator artery and explain the clinical importance. The obturator artery arises from the internal iliac artery in 75% either from its anterior or posterior division in 46.9% or 25% respectively. Further, it arises neither from the anterior nor posterior division of the internal iliac artery but it arises between them in 3.1%. In 25%, the obturator artery arises from the external iliac artery. In case of aneurysmectomy of posterior division, carries a high risk of insufficient of vascular supply for demand structures such as proximal adductors attachment and hip joint. Therefore, vascular surgeons have to pay attention to the posterior division being an origin of the obturator artery beside its usual three classical branches: superior gluteal, iliolumbar and lateral sacral arteries. Further, the obturator artery arising from the external iliac system is in great dangerous of laceration in case of anterior pelvic fracture. Therefore, it may lead to haemorrhagic shock threatening life. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=obturator%20artery" title="obturator artery">obturator artery</a>, <a href="https://publications.waset.org/abstracts/search?q=external%20iliac" title=" external iliac"> external iliac</a>, <a href="https://publications.waset.org/abstracts/search?q=internal%20iliac%20artery" title=" internal iliac artery"> internal iliac artery</a>, <a href="https://publications.waset.org/abstracts/search?q=anterior%20division" title=" anterior division"> anterior division</a>, <a href="https://publications.waset.org/abstracts/search?q=posterior%20division" title=" posterior division"> posterior division</a>, <a href="https://publications.waset.org/abstracts/search?q=superior%20gluteal" title=" superior gluteal"> superior gluteal</a>, <a href="https://publications.waset.org/abstracts/search?q=iliolumbar%20and%20lateral%20sacral" title=" iliolumbar and lateral sacral"> iliolumbar and lateral sacral</a>, <a href="https://publications.waset.org/abstracts/search?q=pubic%20fracture" title=" pubic fracture"> pubic fracture</a>, <a href="https://publications.waset.org/abstracts/search?q=aneurysm" title=" aneurysm"> aneurysm</a>, <a href="https://publications.waset.org/abstracts/search?q=shock" title=" shock"> shock</a> </p> <a href="https://publications.waset.org/abstracts/31813/the-origin-variability-of-the-obturator-artery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/31813.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">357</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Grade and Maximum Tumor Dimension as Determinants of Lymphadenectomy in Patients with Endometrioid Endometrial Cancer (EEC)</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ali%20A.%20Bazzi">Ali A. Bazzi</a>, <a href="https://publications.waset.org/abstracts/search?q=Ameer%20Hamza"> Ameer Hamza</a>, <a href="https://publications.waset.org/abstracts/search?q=Riley%20O%E2%80%99Hara"> Riley O’Hara</a>, <a href="https://publications.waset.org/abstracts/search?q=Kimberly%20Kado"> Kimberly Kado</a>, <a href="https://publications.waset.org/abstracts/search?q=Karen%20H.%20Hagglund"> Karen H. Hagglund</a>, <a href="https://publications.waset.org/abstracts/search?q=Lamia%20Fathallah"> Lamia Fathallah</a>, <a href="https://publications.waset.org/abstracts/search?q=Robert%20T.%20Morris"> Robert T. Morris</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Endometrial Cancer is a common gynecologic malignancy primarily treated with complete surgical staging, which may include complete pelvic and para-aortic lymphadenectomy. The role of lymphadenectomy is controversial, especially the intraoperative indications for the procedure. Three factors are important in decision to proceed with lymphadenectomy: Myometrial invasion, maximum tumor dimension, and histology. Many institutions incorporate these criteria in varying degrees in the decision to proceed with lymphadenectomy. This investigation assesses the use of intraoperatively measured MTD with and without pre-operative histologic grade. Methods: This study compared retrospectively EEC patients with intraoperatively measured MTD ≤2 cm to those with MTD >2 cm from January 1, 2002 to August 31, 2017. This assessment compared those with MTD ≤ 2cm with endometrial biopsy (EB) grade 1-2 to patients with MTD > 2cm with EB grade 3. Lymph node metastasis (LNM), recurrence, and survival were compared in these groups. Results: This study reviewed 222 patient cases. In tumors > 2 cm, LNM occurred in 20% cases while in tumors ≤ 2 cm, LNM was found in 6% cases (p=0.04). Recurrence and mean survival based on last follow up visit in these two groups were not statistically different (p=0.78 and 0.36 respectively). Data demonstrated a trend that when combined with preoperative EB International Federation of Gynecology and Obstetrics (FIGO) grade, a higher proportion of patients with EB FIGO Grade 3 and MTD > 2 cm had LNM compared to those with EB FIGO Grade 1-2 and MTD ≤ 2 cm (43% vs, 11%, p=0.06). LNM was found in 15% of cases in which lymphadenectomy was performed based on current practices, whereas if the criteria of EB FIGO 3 and MTD > 2 cm were used the incidence of LNM would have been 44% cases. However, using this criterion, two patients would not have had their nodal metastases detected. Compared to the current practice, the sensitivity and specificity of the proposed criteria would be 60% and 81%, respectively. The PPV and NPV would be 43% and 90%, respectively. Conclusion: The results indicate that MTD combined with EB FIGO grade can detect LNM in a higher proportion of cases when compared to current practice. MTD combined with EB FIGO grade may eliminate the need of frozen section sampling in a substantial number of cases. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=endometrial%20cancer" title="endometrial cancer">endometrial cancer</a>, <a href="https://publications.waset.org/abstracts/search?q=FIGO%20grade" title=" FIGO grade"> FIGO grade</a>, <a href="https://publications.waset.org/abstracts/search?q=lymphadenectomy" title=" lymphadenectomy"> lymphadenectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=tumor%20size" title=" tumor size"> tumor size</a> </p> <a href="https://publications.waset.org/abstracts/92494/grade-and-maximum-tumor-dimension-as-determinants-of-lymphadenectomy-in-patients-with-endometrioid-endometrial-cancer-eec" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/92494.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">182</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Histopathological, Proliferative, Apoptotic, and Hormonal Characteristics of Various Types of Leiomyomas</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Kiknadze%20T">Kiknadze T</a>, <a href="https://publications.waset.org/abstracts/search?q=Tevdorashvili%20G"> Tevdorashvili G</a>, <a href="https://publications.waset.org/abstracts/search?q=Muzashvili%20T"> Muzashvili T</a>, <a href="https://publications.waset.org/abstracts/search?q=Gachechiladze%20M"> Gachechiladze M</a>, <a href="https://publications.waset.org/abstracts/search?q=Burkadze%20G"> Burkadze G</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Uterine leiomyomas decrease the quality of life by causing significant morbidity among women of reproductive age. Histologically various types of leiomyoma's can be differentiated. We have analysed th histopathological, proliferation, apoptotic, and hormonal profile in different types of leiomyomas. Study included altogether140 cases distributed into the following groups: group I-normal myometrium (20cases), group II-classic leiomyoma (69 cases), group III-cellular leiomyoma (15 cases), group IV-bizarre cell/atypical leiomyoma (22cases), group V-smooth muscle tumors of uncertain malignancy potential (STUMP) (8 cases) and group VI-leiomyosarcoma (6 cases). Together with classic histopathological features such as nuclear atypia, cellularity, presence of mitoses, vasculature and necrosis, immunohistochemical phenotype using antibodies against Ki67,Cas3, ER, and PR were analysed. The results of our study showed that leiomyomas are charterised with variable histopathological and immunohistocthemical phenotype. Histopathological parameters mainly correlate with the degree of malignancy except for two bizarre/atypical leiomyoma and STUMP, where two distinct subgroups could be identified. In bizarre/ atipycal leiomyoma, 31% of cases are characterized with the features of classic leiomyoma, whilst the rest of the cases reveal more atipycal phenotype. In STUMP 37.5 % of cases are characterized with the features of atipycal leiomyomas. The result of the immunohistochemical study also reveald that half of bizarre/atipycal leiomyomas are characterized with the low proliferation index, high apoptotic index, and high ER and PR index, whilst another half is characterized with high proliferation index, low apoptotic index, and low ER and PR index. Similarly, part of the STUMP cases are characterized with low proliferation index, high Er, and PR index and whilst part of the cases are characterized whith high proliferation index, low apoptotic index and low ER and PR index. The results of the histopathological and immunohistochemical study indicate that these two entities represent the heterogenous group of diseases, which might be the explanation of their different prognosis. Presented histopathological and immunohistochemical features should be considered in the diagnosis of myometrial smooth muscle tumors. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=proliferation" title="proliferation">proliferation</a>, <a href="https://publications.waset.org/abstracts/search?q=apoptosis" title=" apoptosis"> apoptosis</a>, <a href="https://publications.waset.org/abstracts/search?q=bizarre%20cell" title=" bizarre cell"> bizarre cell</a>, <a href="https://publications.waset.org/abstracts/search?q=leiomyosarcoma." title=" leiomyosarcoma."> leiomyosarcoma.</a>, <a href="https://publications.waset.org/abstracts/search?q=leiomyoma" title=" leiomyoma"> leiomyoma</a> </p> <a href="https://publications.waset.org/abstracts/158575/histopathological-proliferative-apoptotic-and-hormonal-characteristics-of-various-types-of-leiomyomas" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/158575.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">108</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Morphology and Risk Factors for Blunt Aortic Trauma in Car Accidents: An Autopsy Study</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Ticijana%20Prijon">Ticijana Prijon</a>, <a href="https://publications.waset.org/abstracts/search?q=Branko%20Ermenc"> Branko Ermenc</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Blunt aortic trauma (BAT) includes various morphological changes that occur during deceleration, acceleration and/or body compression in traffic accidents. The various forms of BAT, from limited laceration of the intima to complete transection of the aorta, depends on the force acting on the vessel wall and the tolerance of the aorta to injury. The force depends on the change in velocity, the dynamics of the accident and of the seating position in the car. Tolerance to aortic injury depends on the anatomy, histological structure and pathomorphological alterations due to aging or disease of the aortic wall.An overview of the literature and medical documentation reveals that different terms are used to describe certain forms of BAT, which can lead to misinterpretation of findings or diagnoses. We therefore, propose a classification that would enable uniform systematic screening of all forms of BAT. We have classified BAT into three morphologycal types: TYPE I (intramural), TYPE II (transmural) and TYPE III (multiple) aortic ruptures with appropriate subtypes. Methods: All car accident casualties examined at the Institute of Forensic Medicine from 2001 to 2009 were included in this retrospective study. Autopsy reports were used to determine the occurrence of each morphological type of BAT in deceased drivers, front seat passengers and other passengers in cars and to define the morphology of BAT in relation to the accident dynamics and the age of the fatalities. Results: A total of 391 fatalities in car accidents were included in the study. TYPE I, TYPE II and TYPE III BAT were observed in 10,9%, 55,6% and 33,5%, respectively. The incidence of BAT in drivers, front seat and other passengers was 36,7%, 43,1% and 28,6%, respectively. In frontal collisions, the incidence of BAT was 32,7%, in lateral collisions 54,2%, and in other traffic accidents 29,3%. The average age of fatalities with BAT was 42,8 years and of those without BAT 39,1 years. Conclusion: Identification and early recognition of the risk factors of BAT following a traffic accident is crucial for successful treatment of patients with BAT. Front seat passengers over 50 years of age who have been injured in a lateral collision are the most at risk of BAT. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=aorta" title="aorta">aorta</a>, <a href="https://publications.waset.org/abstracts/search?q=blunt%20trauma" title=" blunt trauma"> blunt trauma</a>, <a href="https://publications.waset.org/abstracts/search?q=car%20accidents" title=" car accidents"> car accidents</a>, <a href="https://publications.waset.org/abstracts/search?q=morphology" title=" morphology"> morphology</a>, <a href="https://publications.waset.org/abstracts/search?q=risk%20factors" title=" risk factors"> risk factors</a> </p> <a href="https://publications.waset.org/abstracts/7478/morphology-and-risk-factors-for-blunt-aortic-trauma-in-car-accidents-an-autopsy-study" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/7478.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">513</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> One Decade Later: The Conundrum of Unrecognized Asherman Syndrome</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Maria%20Francesca%20Lavadia-Gumabao">Maria Francesca Lavadia-Gumabao</a>, <a href="https://publications.waset.org/abstracts/search?q=Mary%20Antoinette%20Salvamante-Torallo"> Mary Antoinette Salvamante-Torallo</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: The fibrous intrauterine adhesions forming inside the uterus and/or cervix in Asherman syndrome can obstruct the internal cervical orifice and may present as a case of outflow tract obstruction. Asherman syndrome is often overlooked since it has no specific presentation and is undetectable by routine physical examinations or diagnostic procedures such as an ultrasound. This paper highlights the delay and elusive diagnosis of Asherman syndrome which negatively impacted the patient’s fertility and quality of life. Case presentation: A 33-year-old woman (gravida 3, para 3) who presented with secondary amenorrhea for thirteen years associated with cyclic pelvic pain and secondary infertility sought a consultation at our institution for evaluation and specialty management. The patient had no other well-established risk factors for Asherman syndrome aside from pregnancy. For more than a decade, she delayed seeking medical care. At presentation, history taking, physical examination, and ultrasound were not helpful in identifying the cause of outflow tract obstruction. Diagnostic hysteroscopy was then performed, during which extensive scarring and fibrosis completely obscured the internal cervical orifice were observed, consistent with the diagnosis of Asherman syndrome (Grade 5B). The patient then underwent ultrasound guided hysteroscopy outflow tract dilatation and responded well to the treatment as she had her menstrual period a month after the procedure and no longer had cyclic pelvic pain with a repeat ultrasound finding of an unremarkable uterus. The hispathology result of the tissues retrieved revealed myometrial fragments with associated old hemorrhage benign endometrial stromal tissues, which failed to show endometrial glands. Conclusion: The delay and elusive diagnosis of Asherman syndrome can be brought about by poor health seeking behavior of patients and difficulty in detecting this condition by routine physical examinations or diagnostic procedures such as an ultrasound. It is, therefore, necessary to include Asherman syndrome in the differential diagnosis of secondary amenorrhea and secondary infertility. With expertise in hysteroscopy, early diagnosis, proper classification in the advent of hysteroscopy, and optimal management can improve patient outcomes. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Asherman%20syndrome" title="Asherman syndrome">Asherman syndrome</a>, <a href="https://publications.waset.org/abstracts/search?q=outflow%20tract%20obstruction" title=" outflow tract obstruction"> outflow tract obstruction</a>, <a href="https://publications.waset.org/abstracts/search?q=secondary%20amenorrhea" title=" secondary amenorrhea"> secondary amenorrhea</a>, <a href="https://publications.waset.org/abstracts/search?q=infertility" title=" infertility"> infertility</a>, <a href="https://publications.waset.org/abstracts/search?q=hysteroscopy" title=" hysteroscopy"> hysteroscopy</a> </p> <a href="https://publications.waset.org/abstracts/193499/one-decade-later-the-conundrum-of-unrecognized-asherman-syndrome" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193499.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">10</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Cytokine Profiling in Cultured Endometrial Cells after Hormonal Treatment</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Mark%20Gavriel">Mark Gavriel</a>, <a href="https://publications.waset.org/abstracts/search?q=Ariel%20J.%20Jaffa"> Ariel J. Jaffa</a>, <a href="https://publications.waset.org/abstracts/search?q=Dan%20Grisaru"> Dan Grisaru</a>, <a href="https://publications.waset.org/abstracts/search?q=David%20Elad"> David Elad</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The human endometrium-myometrium interface (EMI) is the uterine inner barrier without a separatig layer. It is composed of endometrial epithelial cells (EEC) and endometrial stromal cells (ESC) in the endometrium and myometrial smooth muscle cells (MSMC) in the myometrium. The EMI undergoes structural remodeling during the menstruation cycle which are essential for human reproduction. Recently, we co-cultured a layer-by-layer in vitro model of EEC, ESC and MSMC on a synthetic membrane for mechanobiology experiments. We also treated the model with progesterone and β-estradiol in order to mimic the in vivo receptive uterus In the present study we analyzed the cytokines profile in a single layer of EEC the hormonal treated in vitro model of the EMI. The methodologies of this research include simple tissue-engineering . First, we cultured commercial EEC (RL95-2, ATCC® CRL-1671™) in 24-wellplate. Then, we applied an hormonal stimuli protocol with 17-β-estradiol and progesterone in time dependent concentration according to the human physiology that mimics the menstrual cycle. We collected cell supernatant samples of control, pre-ovulation, ovulation and post-ovulaton periods for analysis of the secreted proteins and cytokines. The cytokine profiling was performed using the Proteome Profiler Human XL Cytokine Array Kit (R&D Systems, Inc., USA) that can detect105 human soluble cytokines. The relative quantification of all the cytokines will be analyzed using xMAP – LUMINEX. We conducted a fishing expedition with the 4 membranes Proteome Profiler. We processed the images, quantified the spots intensity and normalized these values by the negative control and reference spots at the membrane. Analyses of the relative quantities that reflected change higher than 5% of the control points of the kit revealed the The results clearly showed that there are significant changes in the cytokine level for inflammation and angiogenesis pathways. Analysis of tissue-engineered models of the uterine wall will enable deeper investigation of molecular and biomechanical aspects of early reproductive stages (e.g. the window of implantation) or developments of pathologies. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=tissue-engineering" title="tissue-engineering">tissue-engineering</a>, <a href="https://publications.waset.org/abstracts/search?q=hormonal%20stimuli" title=" hormonal stimuli"> hormonal stimuli</a>, <a href="https://publications.waset.org/abstracts/search?q=reproduction" title=" reproduction"> reproduction</a>, <a href="https://publications.waset.org/abstracts/search?q=multi-layer%20uterine%20model" title=" multi-layer uterine model"> multi-layer uterine model</a>, <a href="https://publications.waset.org/abstracts/search?q=progesterone" title=" progesterone"> progesterone</a>, <a href="https://publications.waset.org/abstracts/search?q=%CE%B2-estradiol" title=" β-estradiol"> β-estradiol</a>, <a href="https://publications.waset.org/abstracts/search?q=receptive%20uterine%20model" title=" receptive uterine model"> receptive uterine model</a>, <a href="https://publications.waset.org/abstracts/search?q=fertility" title=" fertility"> fertility</a> </p> <a href="https://publications.waset.org/abstracts/149276/cytokine-profiling-in-cultured-endometrial-cells-after-hormonal-treatment" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/149276.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">132</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Placenta A Classical Caesarean Section with Peripartum Hysterectomy at 27+3 Weeks Gestation For Placnta Accreta</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Huda%20Abdelrhman%20Osman%20Ahmed">Huda Abdelrhman Osman Ahmed</a>, <a href="https://publications.waset.org/abstracts/search?q=Paul%20Feyi%20Waboso"> Paul Feyi Waboso</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: Placenta accreta spectrum (PAS) disorders present a significant challenge in obstetric management due to the high risk of hemorrhage and potential complications at delivery. This case describes a 27+3 weeks gestation in a patient with placenta accreta managed with classical cesarean section and peripartum hysterectomy. Case Description: AGravida 4P3 patient presented at 27+3 weeks gestation with painless, unprovoked vaginal bleeding and an estimated blood loss (EBL) of 300 mL. At the 20+5 week anomaly scan, a placenta previa was identified anterior, covering the os anterior uterus and containing lacunae with signs of myometrial thinning. At a 24+1 week scan conducted at a tertiary center, further imaging indicated placenta increta with invasion into the myometrium and potential areas of placenta percreta. The patient’s past obstetric history included three previous cesarean sections, with no significant medical or surgical history. Social history revealed heavy smoking but no alcohol use. No drug allergies were reported. Given the risks associated with PAS, a management plan was formulated, including an MRI at a later stage and cesarean delivery with a possible hysterectomy between 34-36 weeks. However, at 27+3 weeks, the patient experienced another episode of vaginal bleeding EBL 500 ml, necessitating immediate intervention. Management: As the patient was unstable, she was not transferred to the tertiary center. Completed and informed consent was obtained. MDT planning-group and cross-matching 4 units, uterotonics. Tranexamic acid blood products, cryo, cell salvage, 2 obstetric consultants and an anesthetic consultant, blood bank aware and hematologist. HDU bed and ITU availability. This study assisted in performing a classical Caesarean section, Where the urologist inserted JJ ureteric stents. Following this, we also assisted in a total abdominal hysterectomy with the conservation of ovaries. 4 units RBC and 1 unit FFP were transfused. The total blood loss was 2.3 L. Outcome: The procedure successfully achieved hemostasis, and the neonate was delivered with subsequent transfer to a neonatal intensive care unit for management. The patient’s postoperative course was monitored closely with no immediate complications. Discussion: This case highlights the complexity and urgency in managing placenta accreta spectrum disorders, particularly with the added challenges posed by remote location and limited tertiary support. The need for rapid decision-making and interdisciplinary coordination is emphasized in such high-risk obstetric cases. The case also underscores the potential for surgical intervention and the importance of family involvement in emergent care decisions. Conclusion: Placenta accreta spectrum disorders demand meticulous planning and timely intervention. This case contributes to understanding PAS management at earlier gestational ages and provides insights into the challenges posed by access to tertiary care, especially in urgent situations. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Accreta" title="Accreta">Accreta</a>, <a href="https://publications.waset.org/abstracts/search?q=Hysterectomy" title=" Hysterectomy"> Hysterectomy</a>, <a href="https://publications.waset.org/abstracts/search?q=3MDT" title=" 3MDT"> 3MDT</a>, <a href="https://publications.waset.org/abstracts/search?q=prematurity" title=" prematurity"> prematurity</a> </p> <a href="https://publications.waset.org/abstracts/193450/placenta-a-classical-caesarean-section-with-peripartum-hysterectomy-at-273-weeks-gestation-for-placnta-accreta" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/193450.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">11</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Force Sensor for Robotic Graspers in Minimally Invasive Surgery</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Naghmeh%20M.%20Bandari">Naghmeh M. Bandari</a>, <a href="https://publications.waset.org/abstracts/search?q=Javad%20Dargahi"> Javad Dargahi</a>, <a href="https://publications.waset.org/abstracts/search?q=Muthukumaran%20Packirisamy"> Muthukumaran Packirisamy</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Robot-assisted minimally invasive surgery (RMIS) has been widely performed around the world during the last two decades. RMIS demonstrates significant advantages over conventional surgery, e.g., improving the accuracy and dexterity of a surgeon, providing 3D vision, motion scaling, hand-eye coordination, decreasing tremor, and reducing x-ray exposure for surgeons. Despite benefits, surgeons cannot touch the surgical site and perceive tactile information. This happens due to the remote control of robots. The literature survey identified the lack of force feedback as the riskiest limitation in the existing technology. Without the perception of tool-tissue contact force, the surgeon might apply an excessive force causing tissue laceration or insufficient force causing tissue slippage. The primary use of force sensors has been to measure the tool-tissue interaction force in real-time in-situ. Design of a tactile sensor is subjected to a set of design requirements, e.g., biocompatibility, electrical-passivity, MRI-compatibility, miniaturization, ability to measure static and dynamic force. In this study, a planar optical fiber-based sensor was proposed to mount at the surgical grasper. It was developed based on the light intensity modulation principle. The deflectable part of the sensor was a beam modeled as a cantilever Euler-Bernoulli beam on rigid substrates. A semi-cylindrical indenter was attached to the bottom surface the beam at the mid-span. An optical fiber was secured at both ends on the same rigid substrates. The indenter was in contact with the fiber. External force on the sensor caused deflection in the beam and optical fiber simultaneously. The micro-bending of the optical fiber would consequently result in light power loss. The sensor was simulated and studied using finite element methods. A laser light beam with 800nm wavelength and 5mW power was used as the input to the optical fiber. The output power was measured using a photodetector. The voltage from photodetector was calibrated to the external force for a chirp input (0.1-5Hz). The range, resolution, and hysteresis of the sensor were studied under monotonic and harmonic external forces of 0-2.0N with 0 and 5Hz, respectively. The results confirmed the validity of proposed sensing principle. Also, the sensor demonstrated an acceptable linearity (R2 > 0.9). A minimum external force was observed below which no power loss was detectable. It is postulated that this phenomenon is attributed to the critical angle of the optical fiber to observe total internal reflection. The experimental results were of negligible hysteresis (R2 > 0.9) and in fair agreement with the simulations. In conclusion, the suggested planar sensor is assessed to be a cost-effective solution, feasible, and easy to use the sensor for being miniaturized and integrated at the tip of robotic graspers. Geometrical and optical factors affecting the minimum sensible force and the working range of the sensor should be studied and optimized. This design is intrinsically scalable and meets all the design requirements. Therefore, it has a significant potential of industrialization and mass production. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=force%20sensor" title="force sensor">force sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=minimally%20invasive%20surgery" title=" minimally invasive surgery"> minimally invasive surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=optical%20sensor" title=" optical sensor"> optical sensor</a>, <a href="https://publications.waset.org/abstracts/search?q=robotic%20surgery" title=" robotic surgery"> robotic surgery</a>, <a href="https://publications.waset.org/abstracts/search?q=tactile%20sensor" title=" tactile sensor"> tactile sensor</a> </p> <a href="https://publications.waset.org/abstracts/83179/force-sensor-for-robotic-graspers-in-minimally-invasive-surgery" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/83179.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">231</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); 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