CINXE.COM
ExplorEnz: EC 2.1.1.140
<!DOCTYPE HTML PUBLIC "-//W3C//DTD HTML 4.0//EN" "http://www.w3.org/TR/REC-html40/strict.dtd"> <html> <head> <title>ExplorEnz: EC 2.1.1.140</title> <meta http-equiv="Content-Type" content="text/html; charset=iso-8859-1" /> <meta name="keywords" content="EC 2.1.1.140,ExplorEnz,IUBMB,Enzyme Nomenclature Database,Enzyme Classification" /> <meta name="description" content="Enzyme Nomenclature Database" /> <meta name="robots" content="index,nofollow"> <meta name="googlebot" content="index,nofollow" /> <link rel="stylesheet" type="text/css" href="enzyme2.css"> <link rel="shortcut icon" href="favicon.ico" /> <style type="text/css" media="screen"> <!-- #nav a#home { background-color:#f6f6f6; color:#000; } .style1 {color:#6b707a} --> </style> </head> <base href="/query.php?ec=2.1.1.140"> <body> <a href="index.php"> <img src="images/banner_5.gif" alt="The Enzyme Database" width="920 px" height="" border="0" /></a> </div><table border="0" cellborder="0" cellspacing="0" cellpadding="0" width="100%" id="nav"> <tr> <td class="f" nowrap="nowrap" colspan="1" border="0"> <li><a href="./" alt="Home" title="Home"><small>Home</small></a></li> <li><a href="search.php" alt="Simple Search" title="Search the database"><small>Search</small></a></li> <li><a href="class.php" alt="Enzyme Classes" title="Hierarchical view of the Enzyme Classification system"><small>Enzymes by Class</small></a></li> <li><a href="newenz.php" alt="New/Modified Enzymes" title="New/modified enzyme entries"><small>New/Amended Enzymes</small></a></li> <li><a href="stats.php" alt="Enzyme Count" title="Enzyme count"><small>Statistics</small></a></li> <li><a href="forms.php" alt="Forms" title="Submit data on a new enzyme, or report an error"><small>Forms</small></a></li> <li><a href="news.php" alt="News" title="Reports on recent developments in enzyme classification or changes to nomenclature"><small>News</small></a></li> <li><a href="about.php" alt="Help Files, Archives" title="Quick-start Guide, FAQ, Supplements"><small>Information</small></a></li> <li><a href="downloads.php" alt="Downloads" title="Download the database"><small>Downloads</small></a></li> <li></li> </td> </tr> </table> <p> <p> <strong>Your query returned 1 entry.</strong> <a href="query.php?ec=2.1.1.140&pr=on" target="new"><img src="images/print.png" alt="printer_icon" align="center" border="0"></a><small>Printable version</small> <table border="0" cellpadding="2" cellspacing="3" width="100%"> <tr valign="bottom"> <td width="20%" align="right"><a name="1"></a><strong><span style="color : red">EC</span></strong></td> <td width="80%" colspan="1"><strong><span style="color : red">2.1.1.140</span></strong> </td> </tr> <tr> <td width="20%" align="right"><strong>Accepted name:</strong></td> <td width="80%" colspan="1">(<em>S</em>)-coclaurine-<em>N</em>-methyltransferase</td> </tr> <tr> <td width="20%" align="right"><strong>Reaction:</strong></td> <td width="80%" colspan="1"><em>S</em>-adenosyl-<small>L</small>-methionine + (<em>S</em>)-coclaurine = <em>S</em>-adenosyl-<small>L</small>-homocysteine + (<em>S</em>)-<em>N</em>-methylcoclaurine</td> </tr> <tr> <td width="20%" align="right"></td> <td width="80%">For diagram of reticuline-biosynthesis pathway, <a target="new" href="reaction/alkaloid/retic.html">click here</a></td> </tr> <tr valign="top"> <td width="20%" align="right"><strong>Systematic name: </strong></td> <td width="80%" colspan="1"><em>S</em>-adenosyl-<small>L</small>-methionine:(<em>S</em>)-coclaurine-<em>N</em>-methyltransferase</td> </tr> <tr valign="top"> <td width="20%" align="right"><strong>Comments:</strong></td> <td width="80%" colspan="1">The enzyme is specific for the (<em>S</em>)-isomer of coclaurine. Norcoclaurine can also act as an acceptor.</td> </tr> <tr> <td width="20%" align="right"><strong>Links to other databases:</strong></td> <td width="80%" colspan="1"><a href="https://www.brenda-enzymes.org/enzyme.php?ecno=2.1.1.140" target="new">BRENDA</a>, <a href="https://enzyme.expasy.org/EC/2.1.1.140" target="new">EXPASY</a>, <a href="https://www.ncbi.nlm.nih.gov/gene/?term=2.1.1.140%5BEC%5D" target="new">Gene</a>, <a href="https://www.kegg.jp/dbget-bin/www_bget?ec:2.1.1.140" target="new">KEGG</a>, <a href="http://biocyc.org/META/NEW-IMAGE?type=EC-NUMBER&object=EC-2.1.1.140" target="new">MetaCyc</a>, CAS registry number: 167398-06-3</td> </tr> <tr> <td width="20%" align="right" valign="top"><strong>References:</strong></td> <td align="left" valign="top" colspan="1"> <table border="0" cellpadding="0"><tr> <td>1. </td> <td>Loeffler, S., Deus-Neumann, B. and Zenk, M.H. <em>S</em>-Adenosyl-<small>L</small>-methionine: (<em>S</em>)-coclaurine-<em>N</em>-methyltransferase from <em>Tinospora cordifolia</em>. <em>Phytochemistry</em> <strong>38</strong> (1995) 1387–1395. [<a href="https://doi.org/10.4236/health.2010.28144" target="new">DOI</a>] </td> </tr> </td></tr> </table></td></tr> </td></tr> <tr><td colspan="2"><center><small>[EC 2.1.1.140 created 2001]</small></center></td> </tr> <tr> <td> </td> <td></td> </tr> <tr> <td> </td> <td></td> </tr> </table> <br><br><center><font size="1">Data © 2001–2024 IUBMB</font> <br> <font size="1">Web site © 2005–2024 Andrew McDonald</font> <br> </center> </body> </html>