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is-link">Go</button> </div> </div> </form> </div> </div> <ol class="breathe-horizontal" start="1"> <li class="arxiv-result"> <div class="is-marginless"> <p class="list-title is-inline-block"><a href="https://arxiv.org/abs/2112.10074">arXiv:2112.10074</a> <span> [<a href="https://arxiv.org/pdf/2112.10074">pdf</a>, <a href="https://arxiv.org/format/2112.10074">other</a>] </span> </p> <div class="tags is-inline-block"> <span class="tag is-small is-link tooltip is-tooltip-top" data-tooltip="Image and Video Processing">eess.IV</span> <span class="tag is-small is-grey tooltip is-tooltip-top" data-tooltip="Computer Vision and Pattern Recognition">cs.CV</span> <span class="tag is-small is-grey tooltip is-tooltip-top" data-tooltip="Machine Learning">cs.LG</span> </div> <div class="is-inline-block" style="margin-left: 0.5rem"> <div class="tags has-addons"> <span class="tag is-dark is-size-7">doi</span> <span class="tag is-light is-size-7"><a class="" href="https://doi.org/10.59275/j.melba.2022-354b">10.59275/j.melba.2022-354b <i class="fa fa-external-link" aria-hidden="true"></i></a></span> </div> </div> </div> <p class="title is-5 mathjax"> QU-BraTS: MICCAI BraTS 2020 Challenge on Quantifying Uncertainty in Brain Tumor Segmentation - Analysis of Ranking Scores and Benchmarking Results </p> <p class="authors"> <span class="search-hit">Authors:</span> <a href="/search/cs?searchtype=author&query=Mehta%2C+R">Raghav Mehta</a>, <a href="/search/cs?searchtype=author&query=Filos%2C+A">Angelos Filos</a>, <a href="/search/cs?searchtype=author&query=Baid%2C+U">Ujjwal Baid</a>, <a href="/search/cs?searchtype=author&query=Sako%2C+C">Chiharu Sako</a>, <a href="/search/cs?searchtype=author&query=McKinley%2C+R">Richard McKinley</a>, <a href="/search/cs?searchtype=author&query=Rebsamen%2C+M">Michael Rebsamen</a>, <a href="/search/cs?searchtype=author&query=Datwyler%2C+K">Katrin Datwyler</a>, <a href="/search/cs?searchtype=author&query=Meier%2C+R">Raphael Meier</a>, <a href="/search/cs?searchtype=author&query=Radojewski%2C+P">Piotr Radojewski</a>, <a href="/search/cs?searchtype=author&query=Murugesan%2C+G+K">Gowtham Krishnan Murugesan</a>, <a href="/search/cs?searchtype=author&query=Nalawade%2C+S">Sahil Nalawade</a>, <a href="/search/cs?searchtype=author&query=Ganesh%2C+C">Chandan Ganesh</a>, <a href="/search/cs?searchtype=author&query=Wagner%2C+B">Ben Wagner</a>, <a href="/search/cs?searchtype=author&query=Yu%2C+F+F">Fang F. Yu</a>, <a href="/search/cs?searchtype=author&query=Fei%2C+B">Baowei Fei</a>, <a href="/search/cs?searchtype=author&query=Madhuranthakam%2C+A+J">Ananth J. Madhuranthakam</a>, <a href="/search/cs?searchtype=author&query=Maldjian%2C+J+A">Joseph A. Maldjian</a>, <a href="/search/cs?searchtype=author&query=Daza%2C+L">Laura Daza</a>, <a href="/search/cs?searchtype=author&query=Gomez%2C+C">Catalina Gomez</a>, <a href="/search/cs?searchtype=author&query=Arbelaez%2C+P">Pablo Arbelaez</a>, <a href="/search/cs?searchtype=author&query=Dai%2C+C">Chengliang Dai</a>, <a href="/search/cs?searchtype=author&query=Wang%2C+S">Shuo Wang</a>, <a href="/search/cs?searchtype=author&query=Reynaud%2C+H">Hadrien Reynaud</a>, <a href="/search/cs?searchtype=author&query=Mo%2C+Y">Yuan-han Mo</a>, <a href="/search/cs?searchtype=author&query=Angelini%2C+E">Elsa Angelini</a> , et al. (67 additional authors not shown) </p> <p class="abstract mathjax"> <span class="has-text-black-bis has-text-weight-semibold">Abstract</span>: <span class="abstract-short has-text-grey-dark mathjax" id="2112.10074v2-abstract-short" style="display: inline;"> Deep learning (DL) models have provided state-of-the-art performance in various medical imaging benchmarking challenges, including the Brain Tumor Segmentation (BraTS) challenges. However, the task of focal pathology multi-compartment segmentation (e.g., tumor and lesion sub-regions) is particularly challenging, and potential errors hinder translating DL models into clinical workflows. Quantifying… <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2112.10074v2-abstract-full').style.display = 'inline'; document.getElementById('2112.10074v2-abstract-short').style.display = 'none';">▽ More</a> </span> <span class="abstract-full has-text-grey-dark mathjax" id="2112.10074v2-abstract-full" style="display: none;"> Deep learning (DL) models have provided state-of-the-art performance in various medical imaging benchmarking challenges, including the Brain Tumor Segmentation (BraTS) challenges. However, the task of focal pathology multi-compartment segmentation (e.g., tumor and lesion sub-regions) is particularly challenging, and potential errors hinder translating DL models into clinical workflows. Quantifying the reliability of DL model predictions in the form of uncertainties could enable clinical review of the most uncertain regions, thereby building trust and paving the way toward clinical translation. Several uncertainty estimation methods have recently been introduced for DL medical image segmentation tasks. Developing scores to evaluate and compare the performance of uncertainty measures will assist the end-user in making more informed decisions. In this study, we explore and evaluate a score developed during the BraTS 2019 and BraTS 2020 task on uncertainty quantification (QU-BraTS) and designed to assess and rank uncertainty estimates for brain tumor multi-compartment segmentation. This score (1) rewards uncertainty estimates that produce high confidence in correct assertions and those that assign low confidence levels at incorrect assertions, and (2) penalizes uncertainty measures that lead to a higher percentage of under-confident correct assertions. We further benchmark the segmentation uncertainties generated by 14 independent participating teams of QU-BraTS 2020, all of which also participated in the main BraTS segmentation task. Overall, our findings confirm the importance and complementary value that uncertainty estimates provide to segmentation algorithms, highlighting the need for uncertainty quantification in medical image analyses. Finally, in favor of transparency and reproducibility, our evaluation code is made publicly available at: https://github.com/RagMeh11/QU-BraTS. <a class="is-size-7" style="white-space: nowrap;" onclick="document.getElementById('2112.10074v2-abstract-full').style.display = 'none'; document.getElementById('2112.10074v2-abstract-short').style.display = 'inline';">△ Less</a> </span> </p> <p class="is-size-7"><span class="has-text-black-bis has-text-weight-semibold">Submitted</span> 23 August, 2022; <span class="has-text-black-bis has-text-weight-semibold">v1</span> submitted 19 December, 2021; <span class="has-text-black-bis has-text-weight-semibold">originally announced</span> December 2021. </p> <p class="comments is-size-7"> <span class="has-text-black-bis has-text-weight-semibold">Comments:</span> <span class="has-text-grey-dark mathjax">Accepted for publication at the Journal of Machine Learning for Biomedical Imaging (MELBA): https://www.melba-journal.org/papers/2022:026.html</span> </p> <p class="comments is-size-7"> <span class="has-text-black-bis has-text-weight-semibold">Journal ref:</span> Machine.Learning.for.Biomedical.Imaging. 1 (2022) </p> </li> </ol> <div class="is-hidden-tablet">  <span class="help" style="display: inline-block;"><a href="https://github.com/arXiv/arxiv-search/releases">Search v0.5.6 released 2020-02-24</a>  </span> </div> </div> </main> <footer> <div class="columns is-desktop" role="navigation" aria-label="Secondary">  <div class="column"> <div class="columns"> <div class="column"> <ul class="nav-spaced"> <li><a href="https://info.arxiv.org/about">About</a></li> <li><a href="https://info.arxiv.org/help">Help</a></li> </ul> </div> <div class="column"> <ul class="nav-spaced"> <li> <svg xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512" class="icon filter-black" role="presentation"><title>contact arXiv</title><desc>Click here to contact arXiv</desc><path d="M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 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