CINXE.COM

<!DOCTYPE html><html lang="en"><head><meta charSet="utf-8"/><meta name="viewport" content="width=device-width"/><script src="https://cmp.osano.com/6olh2SicG0V81Mlk/1f9d883d-3834-40b9-9a96-6f89a1cda98b/osano.js"></script><title>HCPLive - Clinical news for connected physicians</title><meta name="description" content="HCPLive is a comprehensive clinical news and information portal that provides physicians with up-to-date specialty and disease-specific resources designed to help them provide better care to patients. At HCPLive, you will find breaking news, video interviews with physician experts, in-depth conference coverage, finance and practice management updates, insight and analysis from physician contributors, and more."/><meta property="og:url" content="https://www.hcplive.com "/><meta property="og:title" content="HCPLive - Clinical news for connected physicians"/><meta property="og:image" content="https://s3.amazonaws.com/mjhlifesciences.com/sitelogos/HCPLive_1200x637.png"/><meta property="og:site_name" content="HCP Live"/><meta property="og:description" content="HCPLive is a comprehensive clinical news and information portal that provides physicians with up-to-date specialty and disease-specific resources designed to help them provide better care to patients. At HCPLive, you will find breaking news, video interviews with physician experts, in-depth conference coverage, finance and practice management updates, insight and analysis from physician contributors, and more."/><meta name="twitter:card" content="summary"/><meta name="twitter:title" content="HCPLive - Clinical news for connected physicians"/><meta name="twitter:image" content="https://s3.amazonaws.com/mjhlifesciences.com/sitelogos/HCPLive_1200x637.png"/><meta name="twitter:site" content="@@MDMagazine"/><meta name="twitter:description" content="HCPLive is a comprehensive clinical news and information portal that provides physicians with up-to-date specialty and disease-specific resources designed to help them provide better care to patients. At HCPLive, you will find breaking news, video interviews with physician experts, in-depth conference coverage, finance and practice management updates, insight and analysis from physician contributors, and more."/><meta name="robots" content="max-image-preview:large"/><meta name="robots" content="max-video-preview:-1"/><link rel="preconnect dns-prefetch" href="https://cmp.osano.com"/><link rel="preconnect dns-prefetch" href="https://res.lassomarketing.io"/><link rel="preconnect dns-prefetch" href="https://www.lightboxcdn.com"/><link rel="preconnect dns-prefetch" href="https://pub.doubleverify.com"/><link rel="preconnect dns-prefetch" href="https://cdn.doubleverify.com"/><link rel="preconnect dns-prefetch" href="https://cdn.segment.com"/><link rel="preconnect dns-prefetch" href="https://securepubads.g.doubleclick.net"/><link rel="preconnect dns-prefetch" href="https://pagead2.googlesyndication.com"/><link rel="preconnect dns-prefetch" href="https://cdn.sanity.io"/><link rel="preconnect dns-prefetch" href="https://www.google-analytics.com"/><link rel="preconnect dns-prefetch" href="https://www.googletagmanager.com"/><link rel="preconnect dns-prefetch" href="https://player.vimeo.com"/><link rel="preconnect dns-prefetch" href="https://youtube.com"/><link rel="preconnect dns-prefetch" href="https://connect.facebook.net"/><link rel="preconnect dns-prefetch" href="https://www.facebook.com"/><link rel="preconnect dns-prefetch" href="https://static.ads-twitter.com"/><link rel="preconnect dns-prefetch" href="https://ad.doubleclick.net"/><link rel="preload" href="https://securepubads.g.doubleclick.net/tag/js/gpt.js"/><link rel="preload" href="https://pub.doubleverify.com/signals/pub.js#ctx=20083417&cmp=DV464021"/><link rel="icon" href="/favicon.ico"/><script async="" src="https://securepubads.g.doubleclick.net/tag/js/gpt.js"></script><script src="https://pub.doubleverify.com/signals/pub.js#ctx=20083417&cmp=DV464021"></script><meta name="keywords" content="medicine,medical,news,drugs,treatments,fda,health,healthcare,science,research,pipeline,pharmaceuticals,clinicians,insight,interviews,doctors,providers,allergy,pulmonology,dermatology,ophthalmology,cardiology,endocrinology,diabetes,psychiatry,internal medicine,primary care,rheumatology,gastroenterology,hematology,rare disease,infectious disease"/><script src="https://one.hcplive.com/tagmanager/scripts/one.js"></script><script>window.dataLayer = window.dataLayer || []; window.dataLayer.push({ event: "page_dimensions", pageTitle: "HCPLive - Clinical news for connected physicians", dimension9: "home", dimension11: "", dimension12: "", dimension13: "", dimension14: "", dimension15: "home", dimension18: "", dimension19: "", dimension20: "", });</script><script type="module"> (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-KNMGBBN'); </script><script type="module"> var ALGOLIA_INSIGHTS_SRC = "https://cdn.jsdelivr.net/npm/search-insights@2.4.0"; !function(e,a,t,n,s,i,c){e.AlgoliaAnalyticsObject=s,e[s]=e[s]||function(){ (e[s].queue=e[s].queue||[]).push(arguments)},i=a.createElement(t),c=a.getElementsByTagName(t)[0], i.async=1,i.src=n,c.parentNode.insertBefore(i,c) }(window,document,"script",ALGOLIA_INSIGHTS_SRC,"aa");</script><link rel="canonical" href="https://www.hcplive.com"/><script type="application/ld+json">{"@context":"https://schema.org","@type":"Organization","logo":"https://www.hcplive.com/hcplive_logo_250_w.webp","url":"https://www.hcplive.com","contactPoint":{"@type":"ContactPoint","availableLanguage":["English"]},"description":"HCPLive is a comprehensive clinical news and information portal that provides physicians with up-to-date specialty and disease-specific resources designed to help them provide better care to patients. At HCPLive, you will find breaking news, video interviews with physician experts, in-depth conference coverage, finance and practice management updates, insight and analysis from physician contributors, and more.","sameAs":["https://www.facebook.com/HCPLiveNews/","https://twitter.com/HCPLiveNews ","https://www.linkedin.com/company/hcplive","/rss"]}</script><meta name="next-head-count" content="12"/><link rel="preconnect" href="https://res.lassomarketing.io"/><script async="" type="text/javascript" src="https://www.lightboxcdn.com/static/lightbox_mjh.js"></script><script defer="" src="https://res.lassomarketing.io/scripts/lasso-imp-id-min.js" type="text/javascript"></script> <script defer="" type="text/javascript" src="https://www.googletagservices.com/tag/js/gpt.js"></script> <script type="module"> !function(){var analytics=window.analytics=window.analytics||[];if(!analytics.initialize)if(analytics.invoked)window.console&&console.error&&console.error("Segment snippet included twice.");else{analytics.invoked=!0;analytics.methods=["trackSubmit","trackClick","trackLink","trackForm","pageview","identify","reset","group","track","ready","alias","debug","page","once","off","on","addSourceMiddleware","addIntegrationMiddleware","setAnonymousId","addDestinationMiddleware"];analytics.factory=function(e){return function(){var t=Array.prototype.slice.call(arguments);t.unshift(e);analytics.push(t);return analytics}};for(var e=0;e<analytics.methods.length;e++){var key=analytics.methods[e];analytics[key]=analytics.factory(key)}analytics.load=function(key,e){var t=document.createElement("script");t.type="text/javascript";t.async=!0;t.src="https://cdn.segment.com/analytics.js/v1/" + key + "/analytics.min.js";var n=document.getElementsByTagName("script")[0];n.parentNode.insertBefore(t,n);analytics._loadOptions=e};analytics.SNIPPET_VERSION="4.13.1"; window.LassoImpressionID = lassoImpID(); analytics.load("BBbKMoOjmhsxPnbd2nO6osz3zq67DzuN"); analytics.page({ 'LassoImpressionID': window.LassoImpressionID }); }}(); </script> <link rel="preload" href="/_next/static/css/9e2e309ff782a3b7.css" as="style"/><link rel="stylesheet" href="/_next/static/css/9e2e309ff782a3b7.css" data-n-g=""/><link rel="preload" href="/_next/static/css/638c92711098fe34.css" as="style"/><link rel="stylesheet" href="/_next/static/css/638c92711098fe34.css" data-n-p=""/><noscript data-n-css=""></noscript><script defer="" nomodule="" src="/_next/static/chunks/polyfills-c67a75d1b6f99dc8.js"></script><script src="/_next/static/chunks/webpack-8eb552a8c86fb37e.js" defer=""></script><script src="/_next/static/chunks/framework-45ce3d09104a2cae.js" defer=""></script><script src="/_next/static/chunks/main-c1ce322a402d266c.js" defer=""></script><script src="/_next/static/chunks/pages/_app-6f814750e688eff0.js" defer=""></script><script src="/_next/static/chunks/72585f70-638458469aef554c.js" defer=""></script><script src="/_next/static/chunks/69bd6bf3-c7219ac9ecb38ac9.js" defer=""></script><script src="/_next/static/chunks/f36c6662-e730e1316f9aa347.js" defer=""></script><script src="/_next/static/chunks/8eec4907-bd18a9d50c17fbc1.js" defer=""></script><script src="/_next/static/chunks/065a3ddb-42216585c327b2a5.js" defer=""></script><script src="/_next/static/chunks/9814d858-cb162ab048445baf.js" defer=""></script><script src="/_next/static/chunks/59b4e022-7c8a205b41eac8c0.js" defer=""></script><script src="/_next/static/chunks/4179-91956f2d2c4bf724.js" defer=""></script><script src="/_next/static/chunks/5553-adcf0734802bcf9d.js" defer=""></script><script src="/_next/static/chunks/4159-fb9d5604c2036467.js" defer=""></script><script src="/_next/static/chunks/7107-6cabb37a1b6db405.js" defer=""></script><script src="/_next/static/chunks/6469-ae787191eae770ba.js" defer=""></script><script src="/_next/static/chunks/9100-6af073ac94c2c233.js" defer=""></script><script src="/_next/static/chunks/475-8933b8b0e2730387.js" defer=""></script><script src="/_next/static/chunks/5621-9ff66fb3d33d9b7f.js" defer=""></script><script src="/_next/static/chunks/pages/index-903bccdb791fd457.js" defer=""></script><script src="/_next/static/0zFRHeX4gm9NzHq9OuiA0/_buildManifest.js" defer=""></script><script src="/_next/static/0zFRHeX4gm9NzHq9OuiA0/_ssgManifest.js" defer=""></script><style id="__jsx-1661e6713d4eb9b5">.leaderboardAdWrapper.jsx-1661e6713d4eb9b5{min-height:90px;background:#fff}.leaderboardAdWrapper.jsx-1661e6713d4eb9b5 .AD728x90.jsx-1661e6713d4eb9b5{}@media screen and (min-width:768px){.leader-fixed.jsx-1661e6713d4eb9b5{position:fixed;margin-top:1rem;z-index:999999}}.leaderboardAdWrapper.jsx-1661e6713d4eb9b5 .AD728x90.jsx-1661e6713d4eb9b5 div[id*="google_ads_iframe"].jsx-1661e6713d4eb9b5:empty{height:0px!important}@media screen and (max-width:668px){.leaderboardAdWrapper.jsx-1661e6713d4eb9b5{min-height:0px;position:fixed;background:white;left:0;right:0;top:55px;padding-top:.5rem;padding-bottom:.25rem;z-index:9999}}</style><style id="__jsx-19ede9f0a5a45918">.jsx-19ede9f0a5a45918::-webkit-scrollbar{display:none}</style><style id="__jsx-3601348455">.button.jsx-3601348455{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-3601348455::before{content:"Case-based Simulation";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-3601348455{height:0px}.pill.jsx-3601348455::before{display:block;content:"CME,NCPD";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-3601348455{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-3601348455::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-3601348455::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-3601348455{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-3601348455{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-3601348455{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore08ed9c3f5-b964-4cc3-9eee-0e3007abf905.jsx-3601348455:hover{background:var(--secondary)}.view-more-wrap08ed9c3f5-b964-4cc3-9eee-0e3007abf905.jsx-3601348455{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap08ed9c3f5-b964-4cc3-9eee-0e3007abf905.jsx-3601348455:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-3601348455{background-position:right bottom}.text-white.jsx-3601348455{color:var(--primary)}</style><style id="__jsx-1189330088">.button.jsx-1189330088{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-1189330088::before{content:"In-Person + Virtual Event";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-1189330088{height:0px}.pill.jsx-1189330088::before{display:block;content:"CME";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-1189330088{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-1189330088::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-1189330088::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-1189330088{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-1189330088{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-1189330088{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore1f41bd0a4-e0ec-4521-860b-25fc88ab21f9.jsx-1189330088:hover{background:var(--secondary)}.view-more-wrap1f41bd0a4-e0ec-4521-860b-25fc88ab21f9.jsx-1189330088{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap1f41bd0a4-e0ec-4521-860b-25fc88ab21f9.jsx-1189330088:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-1189330088{background-position:right bottom}.text-white.jsx-1189330088{color:var(--primary)}</style><style id="__jsx-3134297187">.button.jsx-3134297187{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-3134297187::before{content:"Video";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-3134297187{height:0px}.pill.jsx-3134297187::before{display:block;content:"CME,NCPD";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-3134297187{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-3134297187::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-3134297187::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-3134297187{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-3134297187{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-3134297187{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore2d14e8a46-ff99-4fca-9bf9-6b93aaa75ac1.jsx-3134297187:hover{background:var(--secondary)}.view-more-wrap2d14e8a46-ff99-4fca-9bf9-6b93aaa75ac1.jsx-3134297187{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap2d14e8a46-ff99-4fca-9bf9-6b93aaa75ac1.jsx-3134297187:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-3134297187{background-position:right bottom}.text-white.jsx-3134297187{color:var(--primary)}</style><style id="__jsx-3920454624">.button.jsx-3920454624{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-3920454624::before{content:"Video";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-3920454624{height:0px}.pill.jsx-3920454624::before{display:block;content:"CME,NCPD";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-3920454624{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-3920454624::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-3920454624::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-3920454624{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-3920454624{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-3920454624{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore32aef7e83-78fc-4ab5-9ee0-940bb46c07d0.jsx-3920454624:hover{background:var(--secondary)}.view-more-wrap32aef7e83-78fc-4ab5-9ee0-940bb46c07d0.jsx-3920454624{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap32aef7e83-78fc-4ab5-9ee0-940bb46c07d0.jsx-3920454624:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-3920454624{background-position:right bottom}.text-white.jsx-3920454624{color:var(--primary)}</style><style id="__jsx-872076026">.button.jsx-872076026{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-872076026::before{content:"Case-based Simulation";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-872076026{height:0px}.pill.jsx-872076026::before{display:block;content:"CME";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-872076026{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-872076026::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-872076026::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-872076026{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-872076026{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-872076026{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore4d6dcdce4-ecbe-4b82-9024-357b9b5a2318.jsx-872076026:hover{background:var(--secondary)}.view-more-wrap4d6dcdce4-ecbe-4b82-9024-357b9b5a2318.jsx-872076026{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap4d6dcdce4-ecbe-4b82-9024-357b9b5a2318.jsx-872076026:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-872076026{background-position:right bottom}.text-white.jsx-872076026{color:var(--primary)}</style><style id="__jsx-4108833920">.button.jsx-4108833920{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-4108833920::before{content:"Video";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-4108833920{height:0px}.pill.jsx-4108833920::before{display:block;content:"CME,NCPD";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-4108833920{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-4108833920::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-4108833920::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-4108833920{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-4108833920{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-4108833920{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore5724b2643-978e-4be0-9b3e-e15aacc39b41.jsx-4108833920:hover{background:var(--secondary)}.view-more-wrap5724b2643-978e-4be0-9b3e-e15aacc39b41.jsx-4108833920{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap5724b2643-978e-4be0-9b3e-e15aacc39b41.jsx-4108833920:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-4108833920{background-position:right bottom}.text-white.jsx-4108833920{color:var(--primary)}</style><style id="__jsx-3236387575">.button.jsx-3236387575{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-3236387575::before{content:"Video";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-3236387575{height:0px}.pill.jsx-3236387575::before{display:block;content:"CME,NCPD";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-3236387575{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-3236387575::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-3236387575::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-3236387575{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-3236387575{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-3236387575{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore67c9c5349-b821-419d-8155-ac71d963bb15.jsx-3236387575:hover{background:var(--secondary)}.view-more-wrap67c9c5349-b821-419d-8155-ac71d963bb15.jsx-3236387575{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap67c9c5349-b821-419d-8155-ac71d963bb15.jsx-3236387575:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-3236387575{background-position:right bottom}.text-white.jsx-3236387575{color:var(--primary)}</style><style id="__jsx-3159401139">.button.jsx-3159401139{height:0px;position:relative;z-index:999;bottom:176px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%)}.button.jsx-3159401139::before{content:"Video";display:block;position:relative;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:7.5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;z-index:99999999;background-color:var(--primary);color:white;bottom:69px;left:50%;-webkit-transform:translateX(-50%);-moz-transform:translateX(-50%);-ms-transform:translateX(-50%);-o-transform:translateX(-50%);transform:translateX(-50%);font-size:.75rem;text-align:center;line-height:1.15;max-width:200px}.pill.jsx-3159401139{height:0px}.pill.jsx-3159401139::before{display:block;content:"CME,NCPD";height:22px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;background:var(--secondary);color:var(--primary);font-size:10px;font-weight:bold;padding:.25rem .5rem;text-align:center;-webkit-border-top-right-radius:15px;-moz-border-radius-topright:15px;border-top-right-radius:15px;-webkit-border-bottom-left-radius:15px;-moz-border-radius-bottomleft:15px;border-bottom-left-radius:15px;position:relative;float:right;bottom:413px;z-index:99}.bottomDiv.jsx-3159401139{width:100%;display:block;position:relative;top:-10px;height:300px;z-index:99;background:#fff;text-align:center;font-size:.875rem;-webkit-text-decoration-line:none;-moz-text-decoration-line:none;text-decoration-line:none}.bottomDiv.jsx-3159401139::before{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:-54px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:absolute!important;background:white;z-index:1;top:-7px}.bottomDiv.jsx-3159401139::after{content:" ";display:block;width:100%;height:280px;border-top:8px solid var(--primary);left:20px!important;top:-2px;background:white;-webkit-transform:rotate(-7.5deg)!important;-moz-transform:rotate(-7.5deg)!important;-ms-transform:rotate(-7.5deg)!important;-o-transform:rotate(-7.5deg)!important;transform:rotate(-7.5deg)!important;position:absolute!important;z-index:1}.border-div.jsx-3159401139{content:" ";display:block;width:100%;height:280px;left:-50px!important;-webkit-transform:rotate(7.5deg)!important;-moz-transform:rotate(7.5deg)!important;-ms-transform:rotate(7.5deg)!important;-o-transform:rotate(7.5deg)!important;transform:rotate(7.5deg)!important;position:relative;background:white;z-index:99;top:-116px}.content-button.jsx-3159401139{position:relative;border:1px solid var(--primary);min-width:40px;width:-webkit-fit-content;width:-moz-fit-content;width:fit-content;padding:5px 10px;font-weight:bold;-webkit-border-radius:5px;-moz-border-radius:5px;border-radius:5px;font-size:.75rem;z-index:9999;background:var(--primary);color:white;top:150px;left:70px}.content-wrap.jsx-3159401139{position:absolute;width:100%;height:-webkit-fit-content;height:-moz-fit-content;height:fit-content;z-index:99;top:45%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;-webkit-box-orient:vertical;-webkit-box-direction:normal;-webkit-flex-direction:column;-moz-box-orient:vertical;-moz-box-direction:normal;-ms-flex-direction:column;flex-direction:column}#viewMore778417c0d-8dcf-4912-9555-8f4660d32529.jsx-3159401139:hover{background:var(--secondary)}.view-more-wrap778417c0d-8dcf-4912-9555-8f4660d32529.jsx-3159401139{width:100%;height:10%;display:-webkit-box;display:-webkit-flex;display:-moz-box;display:-ms-flexbox;display:flex;background:var(--primary);-webkit-box-pack:justify;-webkit-justify-content:space-between;-moz-box-pack:justify;-ms-flex-pack:justify;justify-content:space-between;-webkit-box-align:center;-webkit-align-items:center;-moz-box-align:center;-ms-flex-align:center;align-items:center;position:absolute;top:90%;z-index:999;background:-webkit-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-moz-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:-o-linear-gradient(left,var(--primary)50%,var(--secondary)50%);background:linear-gradient(to right,var(--primary)50%,var(--secondary)50%);-webkit-background-size:200%100%;-moz-background-size:200%100%;-o-background-size:200%100%;background-size:200%100%;background-position:left bottom;-webkit-transition:all 150ms ease;-moz-transition:all 150ms ease;-o-transition:all 150ms ease;transition:all 150ms ease}.view#more-wrap778417c0d-8dcf-4912-9555-8f4660d32529.jsx-3159401139:hover{background-position:right bottom}.view-more-wrap-wipe.jsx-3159401139{background-position:right bottom}.text-white.jsx-3159401139{color:var(--primary)}</style></head><body><div id="__next" data-reactroot=""><div class="-mb-6"><div class="h-full w-full sticky top-0 z-[999999]"><nav role="navigation" class=" w-full mx-auto hidden lg:block bg-white shadow-md relative"><div class="bg-white" id="topnav"><div class="container px-4 relative justify-between h-16 flex items-center md:items-stretch mx-auto "><div class="h-full flex items-center"><a role="img" aria-label="logo" class="focus:outline-none relative h-12 w-40 mr-6 flex items-center" href="/"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain;object-position:left"/><noscript><img sizes="100vw" srcSet="/_next/image?url=%2Fhcplive_logo_250_w.webp&w=640&q=75 640w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=750&q=75 750w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=828&q=75 828w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=1080&q=75 1080w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=1200&q=75 1200w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=1920&q=75 1920w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=2048&q=75 2048w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=3840&q=75 3840w" src="/_next/image?url=%2Fhcplive_logo_250_w.webp&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain;object-position:left" loading="lazy"/></noscript></span></a><div class="hidden md:block"><div class="bg-white py-2 whitespace-nowrap"><div class="mx-auto md:max-w-4xl lg:max-w-5xl xl:max-w-7xl "><div class="flex gap-4"><a rel="noopener" target="_self" class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" href="/news">News</a><div class=" isolate z-[10000] " data-headlessui-state=""><button class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" type="button" aria-expanded="false" data-headlessui-state="">Media<svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></button><div class="sr-only"><a href="/podcasts" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Podcasts</a><a href="/shows" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Shows</a><a href="/state-of-sciences-presentations" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">State Of Sciences - Presentations</a><a href="/videos" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Videos</a><a href="/webinars" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Webinars</a></div></div><div class=" isolate z-[10000] " data-headlessui-state=""><button class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" type="button" aria-expanded="false" data-headlessui-state="">Multimedia Series<svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></button><div class="sr-only"><a href="/cure-connections" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">CURE Connections®</a><a href="/insights" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Insights</a><a href="/medcast" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Medcast</a><a href="/peer-exchange" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Peer Exchange</a><a href="/peers-and-perspective" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Peers & Perspectives</a><a href="/special-report" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Special Report</a></div></div><div class=" isolate z-[10000] " data-headlessui-state=""><button class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" type="button" aria-expanded="false" data-headlessui-state="">Conferences<svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></button><div class="sr-only"><a href="/latest-conference" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Conference Coverage</a><a href="/conference" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Conference Listing</a></div></div><a rel="noopener" target="_self" class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" href="/sap-partner">Partners</a><a rel="noopener" target="_self" class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" href="/continuing-education">CME/CE</a><div class=" isolate z-[10000] " data-headlessui-state=""><button class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" type="button" aria-expanded="false" data-headlessui-state="">Resources<svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></button><div class="sr-only"><a href="/journals/supplements/digital-supplement" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Digital Supplements</a><a href="/interactive-tools" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Interactive Tools</a><a href="/events" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Live Events</a><a href="/press-release" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Press Release</a><a href="/journals" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Publications</a><a href="/sponsored" rel="noopener" target="_self" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Sponsored</a></div></div><a rel="noopener" target="_self" class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" href="/advisory-board">Advisory Board</a><a rel="noreferrer noopener" target="_blank" class="focus:outline-none border-b-2 border-transparent font-medium cursor-pointer h-full flex items-center text-sm tracking-normal capitalize text-gray-800" href="https://one.hcplive.com/subscribe/">Subscribe</a></div></div></div></div></div><div class="md:flex items-center justify-end hidden"><div class="flex items-center"><div class="md:pr-10 lg:pr-0 h-full flex items-center"><button class="w-6 h-6 relative"><svg xmlns="http://www.w3.org/2000/svg" class="text-gray-800 stroke-current icon icon-tabler icon-tabler-search" viewBox="0 0 24 24" stroke-width="1.5" stroke="currentColor" fill="none" stroke-linecap="round" stroke-linejoin="round"><path stroke="none" d="M0 0h24v24H0z"></path><circle cx="10" cy="10" r="7"></circle><line x1="21" y1="21" x2="15" y2="15"></line></svg></button><div class="hidden bg-secondary p-4 rounded shadow-lg top-16 right-0 overflow-hidden absolute grid place-items-center z-[99999] "><form method="GET" action="/search"><div class="relative"><div class="text-gray-600 absolute ml-3 inset-0 m-auto lg:w-4 lg:h-4 md:w-6 md:h-6"><button aria-label="submit" type="submit" class="absolute block inset-0"><svg xmlns="http://www.w3.org/2000/svg" class="text-gray-600 stroke-current icon icon-tabler icon-tabler-search" viewBox="0 0 24 24" stroke-width="2" stroke="currentColor" fill="none" stroke-linecap="round" stroke-linejoin="round"><path stroke="none" d="M0 0h24v24H0z"></path><circle cx="10" cy="10" r="7"></circle><line x1="21" y1="21" x2="15" y2="15"></line></svg></button></div><input type="text" required="" name="searchTerm" class="block border border-gray-200 focus:outline-none focus:border-indigo-700 lg:w-48 xl:w-64 rounded text-sm text-gray-800 pl-8 py-2" placeholder="Search"/></div></form></div></div></div></div></div></div><div class="bg-primary" id="bottomnav"><div style="max-height:50px" class="px-4 transition-all container justify-between h-12 flex items-center md:items-stretch mx-auto"><div class="h-full w-full flex items-center justify-between relative"><div class="min-w-[170px] z-1 mr-4"><div class="block"><div class=""><div class="mx-auto md:max-w-4xl lg:max-w-5xl xl:max-w-7xl "><div class="flex gap-4 justify-start"><div class=" isolate z-[9999] " data-headlessui-state=""><button class="focus:outline-none rounded font-medium cursor-pointer flex items-center text-xs md:text-sm h-[34px] px-2 md:px-4 tracking-normal capitalize bg-white text-gray-600" type="button" aria-expanded="false" data-headlessui-state="">Choose Specialty<svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></button><nav role="navigation" aria-label="Choose Specialty" class="sr-only"><div><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a></div><div><a rel="noopener" target="_self" href="/clinical/biosimilars" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Biosimilars</a></div><div><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a></div><div><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a></div><div><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a></div><div><a rel="noopener" target="_self" href="/clinical/fda-news" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">FDA News</a></div><div><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a></div><div><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a></div><div><a rel="noopener" target="_self" href="/clinical/geriatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Geriatrics</a><a rel="noopener" target="_self" href="/clinical/geriatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Geriatrics</a><a rel="noopener" target="_self" href="/clinical/geriatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Geriatrics</a></div><div><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a></div><div><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a></div><div><a rel="noopener" target="_self" href="/clinical/hospital-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hospital Medicine</a></div><div><a rel="noopener" target="_self" href="/clinical/infectious-disease" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Infectious Disease</a><a rel="noopener" target="_self" href="/clinical/infectious-disease" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Infectious Disease</a></div><div><a rel="noopener" target="_self" href="/clinical/internal-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Internal Medicine</a></div><div><a rel="noopener" target="_self" href="/clinical/nephrology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Nephrology</a><a rel="noopener" target="_self" href="/clinical/nephrology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Nephrology</a><a rel="noopener" target="_self" href="/clinical/nephrology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Nephrology</a></div><div><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a></div><div><a rel="noopener" target="_self" href="/clinical/obesity-management" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Obesity Management</a></div><div><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a></div><div><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a></div><div><a rel="noopener" target="_self" href="/clinical/pediatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pediatrics</a></div><div><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a></div><div><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a></div><div><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a></div><div><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a></div><div><a rel="noopener" target="_self" href="/clinical/sleep" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Sleep</a><a rel="noopener" target="_self" href="/clinical/sleep" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Sleep</a><a rel="noopener" target="_self" href="/clinical/sleep" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Sleep</a></div><div><a rel="noopener" target="_self" href="/clinical/surgery" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Surgery</a><a rel="noopener" target="_self" href="/clinical/surgery" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Surgery</a></div><div><a rel="noopener" target="_self" href="/clinical/womens-health" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Women's Health</a></div></nav></div></div></div></div></div></div><div class="flex flex-1 items-center overflow-hidden"><span class="text-sm font-bold mr-1 whitespace-pre text-gray-50">Spotlight - </span><ul id="spotlight-links" class="flex gap-2 h-4 overflow-hidden flex-wrap"><li class="text-xs underline whitespace-pre cursor-pointer text-blue-200"><a target="" rel="" href="/clinical/fda-news">FDA News</a></li><span class="border-r w-0 border-gray-400"></span><li class="text-xs underline whitespace-pre cursor-pointer text-blue-200"><a target="" rel="" href="/respiratory-report">The Respiratory Report</a></li><span class="border-r w-0 border-gray-400"></span><li class="text-xs underline whitespace-pre cursor-pointer text-blue-200"><a target="_blank" rel="noreferrer noopener" href="https://www.hcplive.com/interactive-tools/dual-pathway-inhibition/chapter-1">DME & nAMD On-Demand Presentation</a></li></ul></div><div class="w-40 md:w-[280px] relative cursor-pointer md:border-r md:border-l md:ml-4 border-[#c6c6c659] bg-primary"><div class="w-full px-6 py-1 flex items-center justify-center flex-row"><div class="relative w-[160px] h-[24px] flex-1"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="HCP Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="HCP Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="text-gray-200 ml-auto mt-2"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></div></div><ul class="absolute min-w-full md:right-0 md:left-0 bg-primary shadow-lg z-10 space-y-4 pt-4 pb-6 hidden"><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.contagionlive.com/"><p class="flex-none relative max-w-full" style="height:32px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Contagion Live" title="Contagion Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Contagion Live" title="Contagion Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.cgtlive.com/"><p class="flex-none relative max-w-full" style="height:30px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="CGT Live" title="CGT Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="CGT Live" title="CGT Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.neurologylive.com/"><p class="flex-none relative max-w-full" style="height:22px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Neurology Live" title="Neurology Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Neurology Live" title="Neurology Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FNeuro_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FNeuro_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.hcplive.com/"><p class="flex-none relative max-w-full" style="height:26px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="HCP Live" title="HCP Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="HCP Live" title="HCP Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.onclive.com/"><p class="flex-none relative max-w-full" style="height:22px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Oncology Live" title="Oncology Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Oncology Live" title="Oncology Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FOncLive_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FOncLive_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.contemporarypediatrics.com/"><p class="flex-none relative max-w-full" style="height:32px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Contemporary Pediatrics" title="Contemporary Pediatrics" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Contemporary Pediatrics" title="Contemporary Pediatrics" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.contemporaryobgyn.net/"><p class="flex-none relative max-w-full" style="height:37px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Contemporary OBGYN" title="Contemporary OBGYN" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Contemporary OBGYN" title="Contemporary OBGYN" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.urologytimes.com/"><p class="flex-none relative max-w-full" style="height:22px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Urology Times" title="Urology Times" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Urology Times" title="Urology Times" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li></ul></div></div></div></div></nav><nav class="lg:hidden"><div class="w-full shadow-md bg-white sticky top-0 z-40"><div class="flex mx-auto container"><div class=" py-4 flex items-stretch justify-between mx-4 items-center w-full"><div class="flex items-center justify-end"><div class="flex items-center"><div class="h-full flex items-center"><button id="menu" aria-label="open menu" aria-expanded="false" class="focus:outline-none focus:ring-2 focus:ring-gray-700 rounded-md text-gray-800"><svg width="30" height="30" viewBox="0 0 24 24" fill="none" xmlns="http://www.w3.org/2000/svg"><path d="M21 10H3" stroke="#4B5563" stroke-width="1.5" stroke-linecap="round" stroke-linejoin="round"></path><path d="M21 6H3" stroke="#4B5563" stroke-width="1.5" stroke-linecap="round" stroke-linejoin="round"></path><path d="M21 14H3" stroke="#4B5563" stroke-width="1.5" stroke-linecap="round" stroke-linejoin="round"></path><path d="M21 18H3" stroke="#4B5563" stroke-width="1.5" stroke-linecap="round" stroke-linejoin="round"></path></svg></button></div></div></div><div aria-label="logo" role="img" tabindex="0" class="focus:outline-none relative h-10 w-40"><a role="img" aria-label="logo" class="focus:outline-none relative h-12 w-40 mr-6 flex items-center" href="/"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain;object-position:center"/><noscript><img sizes="100vw" srcSet="/_next/image?url=%2Fhcplive_logo_250_w.webp&w=640&q=75 640w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=750&q=75 750w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=828&q=75 828w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=1080&q=75 1080w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=1200&q=75 1200w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=1920&q=75 1920w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=2048&q=75 2048w, /_next/image?url=%2Fhcplive_logo_250_w.webp&w=3840&q=75 3840w" src="/_next/image?url=%2Fhcplive_logo_250_w.webp&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain;object-position:center" loading="lazy"/></noscript></span></a></div><div class="relative w-8 h-8 my grid items-center"><a class="absolute lg:hidden inset-0 mt-1" href="/search"><svg xmlns="http://www.w3.org/2000/svg" class="text-gray-800 stroke-current icon icon-tabler icon-tabler-search" viewBox="0 0 24 24" stroke-width="1.5" stroke="currentColor" fill="none" stroke-linecap="round" stroke-linejoin="round"><path stroke="none" d="M0 0h24v24H0z"></path><circle cx="10" cy="10" r="7"></circle><line x1="21" y1="21" x2="15" y2="15"></line></svg></a></div></div></div><div style="max-height:50px" class="bg-primary px-4 transition-all h-12 md:items-stretch mx-auto" id="bottomnav-mobile"><div class="container justify-between h-12 flex items-center md:items-stretch mx-auto"><div class="h-full w-full flex items-center justify-between relative"><div class="flex flex-1 justify-center xs:justify-start items-center relative group h-full z-50"><div class="z-1"><div class="block"><div class=""><div class="mx-auto md:max-w-4xl lg:max-w-5xl xl:max-w-7xl "><div class="flex gap-4 justify-start"><div class=" isolate z-[9999] " data-headlessui-state=""><button class="focus:outline-none rounded font-medium cursor-pointer flex items-center text-xs md:text-sm h-[34px] px-2 md:px-4 tracking-normal capitalize bg-white text-gray-600" type="button" aria-expanded="false" data-headlessui-state="">Choose Specialty<svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></button><nav role="navigation" aria-label="Choose Specialty" class="sr-only"><div><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a><a rel="noopener" target="_self" href="/clinical/allergy" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Allergy</a></div><div><a rel="noopener" target="_self" href="/clinical/biosimilars" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Biosimilars</a></div><div><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a><a rel="noopener" target="_self" href="/clinical/cardiology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Cardiology</a></div><div><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a><a rel="noopener" target="_self" href="/clinical/dermatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Dermatology</a></div><div><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a><a rel="noopener" target="_self" href="/clinical/endocrinology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Endocrinology</a></div><div><a rel="noopener" target="_self" href="/clinical/fda-news" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">FDA News</a></div><div><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a><a rel="noopener" target="_self" href="/clinical/family-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Family Medicine</a></div><div><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a><a rel="noopener" target="_self" href="/clinical/gastroenterology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Gastroenterology</a></div><div><a rel="noopener" target="_self" href="/clinical/geriatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Geriatrics</a><a rel="noopener" target="_self" href="/clinical/geriatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Geriatrics</a><a rel="noopener" target="_self" href="/clinical/geriatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Geriatrics</a></div><div><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a><a rel="noopener" target="_self" href="/clinical/hematology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hematology</a></div><div><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a><a rel="noopener" target="_self" href="/clinical/hepatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hepatology</a></div><div><a rel="noopener" target="_self" href="/clinical/hospital-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Hospital Medicine</a></div><div><a rel="noopener" target="_self" href="/clinical/infectious-disease" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Infectious Disease</a><a rel="noopener" target="_self" href="/clinical/infectious-disease" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Infectious Disease</a></div><div><a rel="noopener" target="_self" href="/clinical/internal-medicine" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Internal Medicine</a></div><div><a rel="noopener" target="_self" href="/clinical/nephrology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Nephrology</a><a rel="noopener" target="_self" href="/clinical/nephrology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Nephrology</a><a rel="noopener" target="_self" href="/clinical/nephrology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Nephrology</a></div><div><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a><a rel="noopener" target="_self" href="/clinical/neurology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Neurology</a></div><div><a rel="noopener" target="_self" href="/clinical/obesity-management" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Obesity Management</a></div><div><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a><a rel="noopener" target="_self" href="/clinical/ophthalmology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Ophthalmology</a></div><div><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a><a rel="noopener" target="_self" href="/clinical/pain" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pain</a></div><div><a rel="noopener" target="_self" href="/clinical/pediatrics" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pediatrics</a></div><div><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a><a rel="noopener" target="_self" href="/clinical/psychiatry" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Psychiatry</a></div><div><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a><a rel="noopener" target="_self" href="/clinical/pulmonology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Pulmonology</a></div><div><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a><a rel="noopener" target="_self" href="/clinical/rare-diseases" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">RDR Alert®</a></div><div><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a><a rel="noopener" target="_self" href="/clinical/rheumatology" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Rheumatology</a></div><div><a rel="noopener" target="_self" href="/clinical/sleep" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Sleep</a><a rel="noopener" target="_self" href="/clinical/sleep" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Sleep</a><a rel="noopener" target="_self" href="/clinical/sleep" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Sleep</a></div><div><a rel="noopener" target="_self" href="/clinical/surgery" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Surgery</a><a rel="noopener" target="_self" href="/clinical/surgery" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Surgery</a></div><div><a rel="noopener" target="_self" href="/clinical/womens-health" class="flex gap-x-4 py-2 text-sm font-semibold leading-6 text-blue-600 underline">Women's Health</a></div></nav></div></div></div></div></div></div></div><div class="flex-1 grid place-items-end"><div class="w-40 md:w-[280px] relative cursor-pointer md:border-r md:border-l md:ml-4 border-[#c6c6c659] bg-primary"><div class="w-full px-6 py-1 flex items-center justify-center flex-row"><div class="relative w-[160px] h-[24px] flex-1"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="HCP Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="HCP Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fhcplive_networkKO.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="text-gray-200 ml-auto mt-2"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="m11.998 17 7-8h-14z"></path></svg></div></div><ul class="absolute min-w-full md:right-0 md:left-0 bg-primary shadow-lg z-10 space-y-4 pt-4 pb-6 hidden"><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.contagionlive.com/"><p class="flex-none relative max-w-full" style="height:32px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Contagion Live" title="Contagion Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Contagion Live" title="Contagion Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FcontagionLive_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.cgtlive.com/"><p class="flex-none relative max-w-full" style="height:30px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="CGT Live" title="CGT Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="CGT Live" title="CGT Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FCGT_KO_NoTag.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.neurologylive.com/"><p class="flex-none relative max-w-full" style="height:22px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Neurology Live" title="Neurology Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Neurology Live" title="Neurology Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FNeuro_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FNeuro_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FNeuro_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.hcplive.com/"><p class="flex-none relative max-w-full" style="height:26px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="HCP Live" title="HCP Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="HCP Live" title="HCP Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FHCPlive_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.onclive.com/"><p class="flex-none relative max-w-full" style="height:22px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Oncology Live" title="Oncology Live" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Oncology Live" title="Oncology Live" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2FOncLive_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2FOncLive_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2FOncLive_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.contemporarypediatrics.com/"><p class="flex-none relative max-w-full" style="height:32px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Contemporary Pediatrics" title="Contemporary Pediatrics" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Contemporary Pediatrics" title="Contemporary Pediatrics" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fcontemporary_pediatrics_inverted_logo.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.contemporaryobgyn.net/"><p class="flex-none relative max-w-full" style="height:37px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Contemporary OBGYN" title="Contemporary OBGYN" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Contemporary OBGYN" title="Contemporary OBGYN" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fcontemporaryobgyn_inverted_logo.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li><li class="h-fit flex items-center justify-center cursor-pointer py-2 border-y border-transparent hover:border-white"><a class="w-full px-2" href="https://www.urologytimes.com/"><p class="flex-none relative max-w-full" style="height:22px"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Urology Times" title="Urology Times" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Urology Times" title="Urology Times" sizes="100vw" srcSet="/_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=640&q=75 640w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=750&q=75 750w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=828&q=75 828w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=1080&q=75 1080w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=1200&q=75 1200w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=1920&q=75 1920w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=2048&q=75 2048w, /_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FMasterHead%2Fut_logo_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></p></a></li></ul></div> </div></div></div></div></div><div class="fixed top-0 w-[85vw] h-full transform -translate-x-full z-40 transition duration-300 lg:hidden min-h-screen bg-primary shadow-lg" id="mobile-nav"><div class="w-full h-full shadow-lg z-40 fixed overflow-y-auto top-0 flex-col justify-between xl:hidden pb-4 transition duration-500 ease-in-out"><div class="px-5 h-full"><div class="flex flex-col justify-between h-full w-full"><div><div class="mt-6 flex w-full items-center justify-between"><div class="border-b border-gray-200 pb-2 flex items-center justify-between w-full"><div aria-label="logo" role="img" tabindex="0" class="focus:outline-none relative h-16 w-40 "><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain;object-position:left"/><noscript><img sizes="100vw" srcSet="/_next/image?url=%2FHCPlive_white.png&w=640&q=75 640w, /_next/image?url=%2FHCPlive_white.png&w=750&q=75 750w, /_next/image?url=%2FHCPlive_white.png&w=828&q=75 828w, /_next/image?url=%2FHCPlive_white.png&w=1080&q=75 1080w, /_next/image?url=%2FHCPlive_white.png&w=1200&q=75 1200w, /_next/image?url=%2FHCPlive_white.png&w=1920&q=75 1920w, /_next/image?url=%2FHCPlive_white.png&w=2048&q=75 2048w, /_next/image?url=%2FHCPlive_white.png&w=3840&q=75 3840w" src="/_next/image?url=%2FHCPlive_white.png&w=3840&q=75" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain;object-position:left" loading="lazy"/></noscript></span></div><button aria-label="close menu" class="focus:outline-none focus:ring-2 rounded-md text-white pl-8 font-bold"><svg width="18" height="18" viewBox="0 0 14 14" fill="#fff" xmlns="http://www.w3.org/2000/svg"><path d="M13 1L1 13" stroke="#fff" stroke-linecap="round" stroke-width="2" stroke-linejoin="round"></path><path d="M1 1L13 13" stroke="#fff" stroke-linecap="round" stroke-width="2" stroke-linejoin="round"></path></svg></button></div></div><ul role="list" class="flex flex-1 flex-col gap-y-7 mt-6"><li><ul role="list" class="-mx-2 space-y-1"><li><div data-headlessui-state=""><button class="hover:bg-gray-500 flex items-center w-full text-left p-2 gap-x-3 text-sm leading-6 font-semibold text-gray-50" id="headlessui-disclosure-button-undefined" type="button" aria-expanded="false" data-headlessui-state=""><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 320 512" class="text-gray-50 h-5 w-5 shrink-0" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="M285.476 272.971L91.132 467.314c-9.373 9.373-24.569 9.373-33.941 0l-22.667-22.667c-9.357-9.357-9.375-24.522-.04-33.901L188.505 256 34.484 101.255c-9.335-9.379-9.317-24.544.04-33.901l22.667-22.667c9.373-9.373 24.569-9.373 33.941 0L285.475 239.03c9.373 9.372 9.373 24.568.001 33.941z"></path></svg>Spotlight</button></div></li><li><a class="hover:bg-gray-500 block rounded-md py-2 pr-2 pl-10 text-sm leading-6 font-semibold text-gray-50" href="/news"><span>News</span></a></li><li><div data-headlessui-state=""><button class="hover:bg-gray-500 flex items-center w-full text-left p-2 gap-x-3 text-sm leading-6 font-semibold text-gray-50" id="headlessui-disclosure-button-undefined" type="button" aria-expanded="false" data-headlessui-state=""><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 320 512" class="text-gray-50 h-5 w-5 shrink-0" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="M285.476 272.971L91.132 467.314c-9.373 9.373-24.569 9.373-33.941 0l-22.667-22.667c-9.357-9.357-9.375-24.522-.04-33.901L188.505 256 34.484 101.255c-9.335-9.379-9.317-24.544.04-33.901l22.667-22.667c9.373-9.373 24.569-9.373 33.941 0L285.475 239.03c9.373 9.372 9.373 24.568.001 33.941z"></path></svg>Media</button></div></li><li><div data-headlessui-state=""><button class="hover:bg-gray-500 flex items-center w-full text-left p-2 gap-x-3 text-sm leading-6 font-semibold text-gray-50" id="headlessui-disclosure-button-undefined" type="button" aria-expanded="false" data-headlessui-state=""><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 320 512" class="text-gray-50 h-5 w-5 shrink-0" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="M285.476 272.971L91.132 467.314c-9.373 9.373-24.569 9.373-33.941 0l-22.667-22.667c-9.357-9.357-9.375-24.522-.04-33.901L188.505 256 34.484 101.255c-9.335-9.379-9.317-24.544.04-33.901l22.667-22.667c9.373-9.373 24.569-9.373 33.941 0L285.475 239.03c9.373 9.372 9.373 24.568.001 33.941z"></path></svg>Multimedia Series</button></div></li><li><div data-headlessui-state=""><button class="hover:bg-gray-500 flex items-center w-full text-left p-2 gap-x-3 text-sm leading-6 font-semibold text-gray-50" id="headlessui-disclosure-button-undefined" type="button" aria-expanded="false" data-headlessui-state=""><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 320 512" class="text-gray-50 h-5 w-5 shrink-0" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="M285.476 272.971L91.132 467.314c-9.373 9.373-24.569 9.373-33.941 0l-22.667-22.667c-9.357-9.357-9.375-24.522-.04-33.901L188.505 256 34.484 101.255c-9.335-9.379-9.317-24.544.04-33.901l22.667-22.667c9.373-9.373 24.569-9.373 33.941 0L285.475 239.03c9.373 9.372 9.373 24.568.001 33.941z"></path></svg>Conferences</button></div></li><li><a class="hover:bg-gray-500 block rounded-md py-2 pr-2 pl-10 text-sm leading-6 font-semibold text-gray-50" href="/sap-partner"><span>Partners</span></a></li><li><a class="hover:bg-gray-500 block rounded-md py-2 pr-2 pl-10 text-sm leading-6 font-semibold text-gray-50" href="/continuing-education"><span>CME/CE</span></a></li><li><div data-headlessui-state=""><button class="hover:bg-gray-500 flex items-center w-full text-left p-2 gap-x-3 text-sm leading-6 font-semibold text-gray-50" id="headlessui-disclosure-button-undefined" type="button" aria-expanded="false" data-headlessui-state=""><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 320 512" class="text-gray-50 h-5 w-5 shrink-0" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path d="M285.476 272.971L91.132 467.314c-9.373 9.373-24.569 9.373-33.941 0l-22.667-22.667c-9.357-9.357-9.375-24.522-.04-33.901L188.505 256 34.484 101.255c-9.335-9.379-9.317-24.544.04-33.901l22.667-22.667c9.373-9.373 24.569-9.373 33.941 0L285.475 239.03c9.373 9.372 9.373 24.568.001 33.941z"></path></svg>Resources</button></div></li><li><a class="hover:bg-gray-500 block rounded-md py-2 pr-2 pl-10 text-sm leading-6 font-semibold text-gray-50" href="/advisory-board"><span>Advisory Board</span></a></li><li><a class="hover:bg-gray-500 block rounded-md py-2 pr-2 pl-10 text-sm leading-6 font-semibold text-gray-50" href="https://one.hcplive.com/subscribe/"><span>Subscribe</span></a></li></ul></li></ul><div class="flex md:hidden mt-4 items-center gap-2 mt-6 pt-6 border-t"><a rel="noreferrer noopener" target="_blank" href="https://www.facebook.com/HCPLiveNews/"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 448 512" color="#fff" style="color:#fff" height="24" width="24" xmlns="http://www.w3.org/2000/svg"><path d="M400 32H48A48 48 0 0 0 0 80v352a48 48 0 0 0 48 48h137.25V327.69h-63V256h63v-54.64c0-62.15 37-96.48 93.67-96.48 27.14 0 55.52 4.84 55.52 4.84v61h-31.27c-30.81 0-40.42 19.12-40.42 38.73V256h68.78l-11 71.69h-57.78V480H400a48 48 0 0 0 48-48V80a48 48 0 0 0-48-48z"></path></svg></a><a rel="noreferrer noopener" target="_blank" href="https://twitter.com/HCPLiveNews "></a><a rel="noreferrer noopener" target="_blank" href="https://www.linkedin.com/company/hcplive"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 448 512" color="#fff" style="color:#fff" height="27" width="27" xmlns="http://www.w3.org/2000/svg"><path d="M416 32H31.9C14.3 32 0 46.5 0 64.3v383.4C0 465.5 14.3 480 31.9 480H416c17.6 0 32-14.5 32-32.3V64.3c0-17.8-14.4-32.3-32-32.3zM135.4 416H69V202.2h66.5V416zm-33.2-243c-21.3 0-38.5-17.3-38.5-38.5S80.9 96 102.2 96c21.2 0 38.5 17.3 38.5 38.5 0 21.3-17.2 38.5-38.5 38.5zm282.1 243h-66.4V312c0-24.8-.5-56.7-34.5-56.7-34.6 0-39.9 27-39.9 54.9V416h-66.4V202.2h63.7v29.2h.9c8.9-16.8 30.6-34.5 62.9-34.5 67.2 0 79.7 44.3 79.7 101.9V416z"></path></svg></a><a rel="noopener" target="_self" href="/rss"></a></div></div></div></div></div></div></nav></div><div class="container top-ad-div px-4 mx-auto pl-2 pr-2 sm:h-[98px] sm:w-[728px]"><div id="leaderboardWrapper" class="jsx-1661e6713d4eb9b5 leaderboardAdWrapper mx-auto mt-1 flex min-h-0 md:min-h-[90px] justify-center items-center flex-col relative z-[99999] "><div class="jsx-1661e6713d4eb9b5 bg-white md:-translate-x-4"><div class="jsx-1661e6713d4eb9b5 text-[8px] text-center text-gray-600 hidden relative">Advertisement</div><div id="div-gpt-ad-top" class="jsx-1661e6713d4eb9b5 AD728x90 mx-auto text-center x"></div></div></div></div><hr class="mt-8 pt-8 -mb-4 pb-0"/><div id="" class="container mx-auto flex m-1 min-h-[57vh] px-4"><div class="flex-auto w-[calc(100%-300px)] pr-0 md:pr-6 mt-16 sm:mt-0"><div class="relative w-full py-4"><div class="flex items-center space-x-4 border-0 border-b border-secondary select-none py-1"><h2 class="text-3xl text-primary">Latest News</h2></div><div class="grid grid-cols-1 gap-4 md:grid-cols-2"><div class="grid grid-cols-4 gap-3 mt-3 md:col-span-2"><a href="/view/dose-modulation-results-compared-in-risankizumab-guselkumab-for-psoriasis"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%] md:rounded-bl-none md:rounded-tl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis" title="Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:cover"/><noscript><img alt="Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis" title="Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fac119b2ba6368b92294f910860ad1801ffd6b01b-3232x3232.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fac119b2ba6368b92294f910860ad1801ffd6b01b-3232x3232.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fac119b2ba6368b92294f910860ad1801ffd6b01b-3232x3232.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:cover" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/dose-modulation-results-compared-in-risankizumab-guselkumab-for-psoriasis">Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/tim-smith">Tim Smith</a></span></div><p class="text-sm text-gray-500">February 21st 2025</p><p class="text-md block">These data suggest therapeutic modulation of IL-23 inhibitors for psoriasis in those who have shown stability may be a legitimate strategy to ensure efficacy and safety.</p></div></div><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/future-outlook-in-copd"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Future Outlook in COPD" title="Future Outlook in COPD" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:"/><noscript><img alt="Future Outlook in COPD" title="Future Outlook in COPD" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/future-outlook-in-copd">Future Outlook in COPD</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/m-bradley-drummond-md-mhs">M. Bradley Drummond, MD, MHS</a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/meilan-k-han-md-ms">MeiLan K. Han, MD, MS</a></span><div class="relative group w-3"><button><svg stroke="currentColor" fill="none" stroke-width="2" viewBox="0 0 24 24" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path stroke-linecap="round" stroke-linejoin="round" d="M5 12h.01M12 12h.01M19 12h.01M6 12a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0z"></path></svg></button><div class="absolute hidden w-[280px] top-0 flex flex-col mt-6 group-hover:flex"><div class="w-3 h-3 -mb-2 rotate-45 bg-[#eee] ml-[2px]"></div><span class="relative z-10 p-2 text-xs leading-none whitespace-no-wrap bg-[#eee] shadow-lg"><ul><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/emily-wan-md-mph">Emily Wan, MD MPH</a></li><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/ravi-kalhan-md-ms">Ravi Kalhan, MD, MS</a></li></ul></span></div></div></div><p class="text-sm text-gray-500">February 21st 2025</p><p class="text-md hidden">Panelists discuss how chronic obstructive pulmonary disease (COPD) management is evolving with personalized therapies, nonpharmacological care, and advanced treatments. Early diagnosis, adherence, and innovation offer hope for improved outcomes and quality of life.</p></div></div><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/omalizumab-linked-to-greatest-rate-of-hypersensitivity-reactions-atopic-diseases"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Valerie Jaroenpuntaruk, MD I Credit: the Mayo Clinic" title="Valerie Jaroenpuntaruk, MD I Credit: the Mayo Clinic" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:"/><noscript><img alt="Valerie Jaroenpuntaruk, MD I Credit: the Mayo Clinic" title="Valerie Jaroenpuntaruk, MD I Credit: the Mayo Clinic" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ffc268f58f4ab164e0856cf8e8fdfb63765f22855-348x446.png%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ffc268f58f4ab164e0856cf8e8fdfb63765f22855-348x446.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ffc268f58f4ab164e0856cf8e8fdfb63765f22855-348x446.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/omalizumab-linked-to-greatest-rate-of-hypersensitivity-reactions-atopic-diseases">Omalizumab Linked to Greatest Rate of Hypersensitivity Reactions in Atopic Diseases</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/chelsie-derman">Chelsie Derman</a></span></div><p class="text-sm text-gray-500">February 21st 2025</p><p class="text-md hidden">A study analyzed hypersensitivity reactions to biologics for atopic diseases, highlighting reaction types, severity, and biologic discontinuation rates.</p></div></div><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/vaccination-and-pulmonary-rehabilitation-in-copd"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Vaccination and Pulmonary Rehabilitation in COPD" title="Vaccination and Pulmonary Rehabilitation in COPD" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:"/><noscript><img alt="Vaccination and Pulmonary Rehabilitation in COPD" title="Vaccination and Pulmonary Rehabilitation in COPD" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/vaccination-and-pulmonary-rehabilitation-in-copd">Vaccination and Pulmonary Rehabilitation in COPD</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/m-bradley-drummond-md-mhs">M. Bradley Drummond, MD, MHS</a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/meilan-k-han-md-ms">MeiLan K. Han, MD, MS</a></span><div class="relative group w-3"><button><svg stroke="currentColor" fill="none" stroke-width="2" viewBox="0 0 24 24" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path stroke-linecap="round" stroke-linejoin="round" d="M5 12h.01M12 12h.01M19 12h.01M6 12a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0z"></path></svg></button><div class="absolute hidden w-[280px] top-0 flex flex-col mt-6 group-hover:flex"><div class="w-3 h-3 -mb-2 rotate-45 bg-[#eee] ml-[2px]"></div><span class="relative z-10 p-2 text-xs leading-none whitespace-no-wrap bg-[#eee] shadow-lg"><ul><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/emily-wan-md-mph">Emily Wan, MD MPH</a></li><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/ravi-kalhan-md-ms">Ravi Kalhan, MD, MS</a></li></ul></span></div></div></div><p class="text-sm text-gray-500">February 21st 2025</p><p class="text-md hidden">Panelists discuss how key nonpharmacological interventions include vaccinations to prevent infections, pulmonary rehabilitation to improve function, and lung cancer screening for high-risk patients to enable early detection.</p></div></div><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/new-biliary-atresia-guidance-released-american-academy-pediatrics"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Sanjiv Harpavat, MD, PhD | Credit: American Liver Foundation" title="Sanjiv Harpavat, MD, PhD | Credit: American Liver Foundation" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:"/><noscript><img alt="Sanjiv Harpavat, MD, PhD | Credit: American Liver Foundation" title="Sanjiv Harpavat, MD, PhD | Credit: American Liver Foundation" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0fd711f2bd49110973379ae60d69627fa166d7e4-750x750.png%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0fd711f2bd49110973379ae60d69627fa166d7e4-750x750.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0fd711f2bd49110973379ae60d69627fa166d7e4-750x750.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/new-biliary-atresia-guidance-released-american-academy-pediatrics">New Biliary Atresia Guidance Released by American Academy of Pediatrics</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/abigail-brooks">Abigail Brooks, MA</a></span></div><p class="text-sm text-gray-500">February 21st 2025</p><p class="text-md hidden">The strategy detailed in the guidance aids the early identification of infants with biliary atresia and is intended for use between 2 and 4 weeks of life.</p></div></div></div></div><div class="border-y border-secondary py-4"><div class="bg-primary swiper mySwiper"><div class="swiper-wrapper"><div class="swiper-slide" data-swiper-autoplay="undefined"><a target="_blank" href="https://www.hcplive.com/podcasts/lungcast"><div class="relative bg-primary cursor-pointer"><div class="w-full h-[250px] xs:h-[300px] sm:h-[350px] md:h-[300px] lg:h-[400px] xl:h-[500px] select-none "><img class="w-full h-full object-contain md:object-fill" src="https://cdn.sanity.io/images/0vv8moc6/hcplive/99b45b5c8555524da335c771be1d87b954404835-1200x600.png/LungcastFeature.png?w=900&fit=crop&auto=format" alt="Lungcast"/><div class="w-full h-full flex items-center justify-center absolute top-0 p-8 bg-[#00000040]"><div></div></div></div></div></a></div><div class="swiper-slide" data-swiper-autoplay="undefined"><a target="_blank" href="https://www.hcplive.com/podcasts/dont-miss-a-beat"><div class="relative bg-primary cursor-pointer"><div class="w-full h-[250px] xs:h-[300px] sm:h-[350px] md:h-[300px] lg:h-[400px] xl:h-[500px] select-none "><img class="w-full h-full object-contain md:object-fill" src="https://cdn.sanity.io/images/0vv8moc6/hcplive/f42da6a69af6abf349a8739e36c3c757ce137e8a-1200x600.png/DontMissABeatFeature.png?w=900&fit=crop&auto=format" alt="Don’t Miss a Beat"/></div></div></a></div><div class="swiper-slide" data-swiper-autoplay="undefined"><a target="_blank" href="https://www.hcplive.com/podcasts/diabetes-dialogue"><div class="relative bg-primary cursor-pointer"><div class="w-full h-[250px] xs:h-[300px] sm:h-[350px] md:h-[300px] lg:h-[400px] xl:h-[500px] select-none "><img class="w-full h-full object-contain md:object-fill" src="https://cdn.sanity.io/images/0vv8moc6/hcplive/beb8dd963b15661be9245a4e6abc80b22d913196-1200x600.png/DiabetesDialogueFeature.png?w=900&fit=crop&auto=format" alt="Diabetes Dialogue"/></div></div></a></div><div class="swiper-slide" data-swiper-autoplay="undefined"><a target="_blank" href="https://www.hcplive.com/podcasts/new-insight"><div class="relative bg-primary cursor-pointer"><div class="w-full h-[250px] xs:h-[300px] sm:h-[350px] md:h-[300px] lg:h-[400px] xl:h-[500px] select-none "><img class="w-full h-full object-contain md:object-fill" src="https://cdn.sanity.io/images/0vv8moc6/hcplive/c24dea9a5ca5fb10b4485d0edcac7fe471c4c949-1200x600.png/NewInsightFeature.png?w=900&fit=crop&auto=format" alt="New Insight with Dr. Veeral Sheth"/></div></div></a></div><div class="swiper-slide" data-swiper-autoplay="undefined"><a target="_blank" href="https://www.hcplive.com/shows/crisis-point"><div class="relative bg-primary cursor-pointer"><div class="w-full h-[250px] xs:h-[300px] sm:h-[350px] md:h-[300px] lg:h-[400px] xl:h-[500px] select-none "><img class="w-full h-full object-contain md:object-fill" src="https://cdn.sanity.io/images/0vv8moc6/hcplive/f9474953f8fe890c8941e21a9637a272bdff3881-1200x600.png/CrisisPointFeature.png?w=900&fit=crop&auto=format" alt="Crisis Point"/></div></div></a></div></div><div class="swiper-pagination"></div></div></div><div class="relative w-full py-4"><div class="flex items-center space-x-4 border-0 border-b border-secondary select-none py-1"><h2 class="text-3xl text-primary">Conference Coverage</h2><a class="text-sm text-primary flex items-center" href="/latest-conference"><span>View All</span><svg xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 24 24" class="w-3 h-3 -mr-2"><path stroke-linecap="round" stroke-linejoin="round" stroke-width="1.5" stroke="currentColor" d="M8.25 4.5l7.5 7.5-7.5 7.5"></path></svg><svg xmlns="http://www.w3.org/2000/svg" fill="none" viewBox="0 0 24 24" class="w-3 h-3 -mr-2"><path stroke-linecap="round" stroke-linejoin="round" stroke-width="1.5" stroke="currentColor" d="M8.25 4.5l7.5 7.5-7.5 7.5"></path></svg></a></div><div class="grid grid-cols-1 gap-4 md:grid-cols-2"><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/tapinarof-consistent-efficacy-across-body-regions-ad"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" title="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:cover"/><noscript><img alt="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" title="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:cover" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/tapinarof-consistent-efficacy-across-body-regions-ad">Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span></div><p class="text-sm text-gray-500">February 21st 2025</p><p class="text-md hidden">In new data to be presented at AAAAI, the therapy was well-tolerated in people as young as 2 years old.</p></div></div><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/add-on-remibrutinib-quickly-improves-urticaria-control-csu"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" title="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:"/><noscript><img alt="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" title="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/add-on-remibrutinib-quickly-improves-urticaria-control-csu">Add-on Remibrutinib Quickly Improves Urticaria Control in CSU</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span></div><p class="text-sm text-gray-500">February 20th 2025</p><p class="text-md hidden">By week 52, remibrutinib and placebo-to-remibrutinib groups had similar levels of urticaria control.</p></div></div><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/ruxolitinib-clinical-benefit-children-adults-atopic-dermatitis"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" title="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:"/><noscript><img alt="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" title="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/ruxolitinib-clinical-benefit-children-adults-atopic-dermatitis">Ruxolitinib Shows Clinical Benefit in Children, Adults With Atopic Dermatitis</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span></div><p class="text-sm text-gray-500">February 19th 2025</p><p class="text-md hidden">Data from 3 pooled phase 3 studies in children, adolescents, and adults will be presented at the AAAI/WAO Joint Congress.</p></div></div><div class="grid grid-cols-4 gap-3 mt-3 "><a href="/view/unmet-need-for-advanced-chronic-spontaneous-urticaria-treatments-highlighted-in-study"><div class="w-full aspect-square overflow-hidden rounded-bl-[10%]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27250%27/%3e"/></span><img alt="Jonathan Bernstein, MD, FAAAAI I Credit: Bernstein Allergy Group" title="Jonathan Bernstein, MD, FAAAAI I Credit: Bernstein Allergy Group" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" class="object-cover w-full h-full" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:"/><noscript><img alt="Jonathan Bernstein, MD, FAAAAI I Credit: Bernstein Allergy Group" title="Jonathan Bernstein, MD, FAAAAI I Credit: Bernstein Allergy Group" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc3aa3c1592a69f9e41f5005a3d21ee1879cbef77-704x762.png%3Ffit%3Dcrop%26auto%3Dformat&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc3aa3c1592a69f9e41f5005a3d21ee1879cbef77-704x762.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc3aa3c1592a69f9e41f5005a3d21ee1879cbef77-704x762.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:" class="object-cover w-full h-full" loading="lazy"/></noscript></span></div></a><div class="col-span-3 space-y-1"><a class="font-bold text-md md:text-lg" href="/view/unmet-need-for-advanced-chronic-spontaneous-urticaria-treatments-highlighted-in-study">Unmet Need for Advanced Chronic Spontaneous Urticaria Treatments Highlighted in Study</a><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/chelsie-derman">Chelsie Derman</a></span></div><p class="text-sm text-gray-500">February 18th 2025</p><p class="text-md hidden">A study found many patients with chronic spontaneous urticaria need add-on or higher-dose therapies, revealing gaps in treatment. Findings will be presented at AAAAI 2025.</p></div></div></div></div><div class="jsx-19ede9f0a5a45918 py-4 relative px-0"><div class="jsx-19ede9f0a5a45918 "><div class="flex justify-between items-center py-1 space-x-4 border-0 select-none sm:border-b border-secondary"><div class="text-3xl text-primary ">Video Series</div></div></div><div style="scroll-snap-type:none" class="jsx-19ede9f0a5a45918 flex items-start overflow-x-auto space-x-4 py-4 relative mx-auto w-[calc(100%-64px)]"><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/future-outlook-in-copd"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/vaccination-and-pulmonary-rehabilitation-in-copd"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/how-btk-inhibitors-differ-from-current-csu-treatment-approaches"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/btk-inhibition-as-a-strategy-for-csu-treatment"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/safety-data-with-biologics-in-atopic-dermatitis"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/use-of-combination-therapy-in-atopic-dermatitis"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/a-primary-care-perspective-on-diagnosing-atopic-dermatitis"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/considerations-for-switching-systemic-agents-in-atopic-dermatitis"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/expectations-for-efficacy-and-duration-of-response-with-systemic-atopic-dermatitis-treatments"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png%2FMarketing%2520Image%2520-%25202025-01-03T145812.788.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/considerations-for-diagnosis-of-atopic-dermatitis-in-adults"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png%2Fmarketing%2520image%2520(5).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/maintenance-therapy-and-adherence-to-copd-treatment"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/ensifentrine-enhance-trials-in-copd"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png%2FMarketing%2520Image%2520(68).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/current-csu-treatment-approach-and-the-role-of-bruton-tyrosine-kinase"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/pathophysiology-of-chronic-spontaneous-urticaria"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%2FTL.00_00_24_13.Still002.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/switching-or-staying-within-the-treatment-class"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fcc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png%2FMarketing%2520Image%2520-%25202024-12-24T091913.556.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a></div></div><div class="jsx-19ede9f0a5a45918 py-4 relative px-0"><div class="jsx-19ede9f0a5a45918 "><div class="flex justify-between items-center py-1 space-x-4 border-0 select-none sm:border-b border-secondary"><div class="text-3xl text-primary ">Video Interviews</div></div></div><div style="scroll-snap-type:none" class="jsx-19ede9f0a5a45918 flex items-start overflow-x-auto space-x-4 py-4 relative mx-auto w-[calc(100%-64px)]"><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/investigating-brensocatib-first-treatment-bronchiectasis-chalmers"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%2Fchalmers.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%2FW.%2520Lloyd%2520Clark%252C%2520MD.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/ai-in-dermatology-emerging-insights-and-diverging-perspectives"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%2Fpexels-ivan-samkov-4989171.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/skin-of-color-savvy-news-update-addressing-disparities-black-history-month-mentorship-opportunities"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%2FHCPLive%2520SOCS%2520Logo%2520update.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/the-medical-sisterhood-white-coats-wingmen-how-men-can-uplift-women-in-medicine"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%2FPodcast%2520Square%2520Thumbs%2520(4).png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/understanding-angioedema-urticaria-bernstein"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg%2FJonathan-Bernstein-Clinic.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/identifying-b-cell-depleting-agents-lupus-nephritis-furie"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg%2FRichard%252520Alan%252520Furie%252C%252520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/improving-fibrosis-risk-stratification-metald-brian-lee-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png%2FScreenshot%25202025-02-13%2520at%25203.18.07%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/transformations-in-aortic-disease-management-with-mehrdad-ghoreishi-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg%2FMehrdad%2520Ghoreishi%252C%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/importance-of-birch-triterpene-findings-for-epidermolysis-bullosa-with-anna-bruckner-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/phase-3-findings-birch-triterpenes-epidermolysis-bullosa-anna-bruckner-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg%2FAnna%2520Bruckner%2520MD.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/safety-profile-accessibility-tapinarof-cream-atopic-dermatitis-adelaide-hebert-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/impact-of-tapinarof-cream-approval-for-atopic-dermatitis-adelaide-hebert-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg%2FHebert-Adelaide.jpeg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/metabolic-surgery-benefit-mash-related-cirrhosis-soba-laique-md"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-video"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="" title="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="" title="" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png%2FScreenshot%25202025-02-03%2520at%25204.36.36%25E2%2580%25AFPM.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a></div></div><div class="jsx-19ede9f0a5a45918 py-4 relative px-0"><div class="jsx-19ede9f0a5a45918 "><div class="flex justify-between items-center py-1 space-x-4 border-0 select-none sm:border-b border-secondary"><div class="text-3xl text-primary ">Podcasts</div></div></div><div style="scroll-snap-type:none" class="jsx-19ede9f0a5a45918 flex items-start overflow-x-auto space-x-4 py-4 relative mx-auto w-[calc(100%-64px)]"><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/skin-of-color-savvy-news-update-addressing-disparities-black-history-month-mentorship-opportunities"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, & Mentorship Opportunities" title="Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, & Mentorship Opportunities" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, & Mentorship Opportunities" title="Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, & Mentorship Opportunities" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/the-medical-sisterhood-white-coats-wingmen-how-men-can-uplift-women-in-medicine"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Medical Sisterhood: James Del Rosso, DO" title="Medical Sisterhood: James Del Rosso, DO" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Medical Sisterhood: James Del Rosso, DO" title="Medical Sisterhood: James Del Rosso, DO" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/diabetes-dialogue-omnipod-5-and-medtronic-780g-for-type-2-diabetes"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Default thumbnail for Diabetes Dialogue, featuring podcast logo and headshots of hosts." title="Default thumbnail for Diabetes Dialogue, featuring podcast logo and headshots of hosts." src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Default thumbnail for Diabetes Dialogue, featuring podcast logo and headshots of hosts." title="Default thumbnail for Diabetes Dialogue, featuring podcast logo and headshots of hosts." sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fd42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/kidney-compass-applying-hierarchical-composite-endpoints-kidney-disease-trials"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Kidney Compass: Navigating Clinical Trials" title="Kidney Compass: Navigating Clinical Trials" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Kidney Compass: Navigating Clinical Trials" title="Kidney Compass: Navigating Clinical Trials" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/kidney-compass-addressing-skepticism-around-hces-nephrology"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Kidney Compass: Navigating Clinical Trials" title="Kidney Compass: Navigating Clinical Trials" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Kidney Compass: Navigating Clinical Trials" title="Kidney Compass: Navigating Clinical Trials" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/kidney-compass-understanding-hces-nephrology-clinical-trials"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Kidney Compass: Navigating Clinical Trials" title="Kidney Compass: Navigating Clinical Trials" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Kidney Compass: Navigating Clinical Trials" title="Kidney Compass: Navigating Clinical Trials" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/kidney-compass-hierarchical-composite-endpoints-nephrology-dustin-little-md-niels-jongs-phd"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Kidney Compass: Navigating Clinical Tr" title="Kidney Compass: Navigating Clinical Tr" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Kidney Compass: Navigating Clinical Tr" title="Kidney Compass: Navigating Clinical Tr" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F513a7a8843e2e6442581970b54b4ddc278e6628c-300x300.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/medical-ethics-unpacked-glp-1-allocation-and-challenges-of-equitable-access"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Medical Ethics Unpacked: GLP-1 Allocation" title="Medical Ethics Unpacked: GLP-1 Allocation" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Medical Ethics Unpacked: GLP-1 Allocation" title="Medical Ethics Unpacked: GLP-1 Allocation" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/what-is-the-global-lung-function-initiative-its-purpose-lung-function-testing-"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?" title="What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?" title="What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a><a id="" class="w-[200px] h-fit space-y-3 flex-none select-none no-underline" style="scroll-snap-align:center;text-decoration:none" href="/view/skin-of-color-savvy-pigmentary-disorders-in-skin-of-color-with-nada-elbuluk-md-and-michelle-rodrigues-mbbs"><div class="w-full shadow-md shadow-gray-800 overflow-hidden relative bg-white aspect-square"><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:absolute;top:0;left:0;bottom:0;right:0"><img alt="Skin of Color Savvy: Pigmentary Disorders in Skin of Color, with Nada Elbuluk, MD, and Michelle Rodrigues, MBBS" title="Skin of Color Savvy: Pigmentary Disorders in Skin of Color, with Nada Elbuluk, MD, and Michelle Rodrigues, MBBS" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain"/><noscript><img alt="Skin of Color Savvy: Pigmentary Disorders in Skin of Color, with Nada Elbuluk, MD, and Michelle Rodrigues, MBBS" title="Skin of Color Savvy: Pigmentary Disorders in Skin of Color, with Nada Elbuluk, MD, and Michelle Rodrigues, MBBS" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=30 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=30 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=30 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=30 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=30 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=30 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=30 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=30" decoding="async" data-nimg="fill" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:contain" loading="lazy"/></noscript></span></div><div class="w-full flex-wrap text-center text-sm mt-4 font-light no-underline text-gray-700"></div></a></div></div><div class="jsx-19ede9f0a5a45918 py-4 relative px-0"><div class="jsx-19ede9f0a5a45918 "><div class="flex justify-between items-center py-1 space-x-4 border-0 select-none sm:border-b border-secondary"><div class="text-primary text-3xl">Continuing Medical Education</div></div></div><div style="scroll-snap-type:none" class="jsx-19ede9f0a5a45918 flex items-start overflow-x-auto space-x-4 py-4 relative mx-auto w-full md:w-[calc(100%-64px)]"><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-3601348455 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/simulated-diagnosing-and-treating-alzheimers-disease-in-the-modern-era?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-3601348455 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-3601348455 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fddcpnrxgcu4a-Simulated_ADTICatalog750x361.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fddcpnrxgcu4a-Simulated_ADTICatalog750x361.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fddcpnrxgcu4a-Simulated_ADTICatalog750x361.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-3601348455 bottomDiv"></div><div class="jsx-3601348455 border-div"></div><div class="jsx-3601348455 pill"></div><noscript class="jsx-3601348455">Case-based Simulation</noscript><noscript class="jsx-3601348455">CME,NCPD</noscript><div class="jsx-3601348455 content-wrap"><div class="jsx-3601348455 w-full h-fit mb-4"><p class="jsx-3601348455 text-xs px-4 text-center text-[#39485F] font-bold">SimulatED™: Diagnosing and Treating Alzheimer’s Disease in the Modern Era</p></div></div><div class="jsx-3601348455 view-more-wrap08ed9c3f5-b964-4cc3-9eee-0e3007abf905"><div class="jsx-3601348455 flex justify-center w-[50%]"><p id="viewMoreText08ed9c3f5-b964-4cc3-9eee-0e3007abf905" class="jsx-3601348455 text-sm text-[#ffffff]">View More</p></div><div id="viewMore08ed9c3f5-b964-4cc3-9eee-0e3007abf905" class="jsx-3601348455 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-3601348455"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-3601348455 button"></div></a><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-1189330088 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/diabetes-management?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-1189330088 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-1189330088 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F6y9k5j6nl3md-ACP25_CGM_TICatalog750x3612x1.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F6y9k5j6nl3md-ACP25_CGM_TICatalog750x3612x1.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F6y9k5j6nl3md-ACP25_CGM_TICatalog750x3612x1.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-1189330088 bottomDiv"></div><div class="jsx-1189330088 border-div"></div><div class="jsx-1189330088 pill"></div><noscript class="jsx-1189330088">In-Person + Virtual Event</noscript><noscript class="jsx-1189330088">CME</noscript><div class="jsx-1189330088 content-wrap"><div class="jsx-1189330088 w-full h-fit mb-4"><p class="jsx-1189330088 text-xs px-4 text-center text-[#39485F] font-bold">Cases and Conversations™: A Horizon View of Continuous Monitoring Systems for Diabetes Management</p></div><p class="jsx-1189330088 text-center text-xs font-semibold px-4">April 3, 2025</p></div><div class="jsx-1189330088 view-more-wrap1f41bd0a4-e0ec-4521-860b-25fc88ab21f9"><div class="jsx-1189330088 flex justify-center w-[50%]"><p id="viewMoreText1f41bd0a4-e0ec-4521-860b-25fc88ab21f9" class="jsx-1189330088 text-sm text-[#ffffff]">Register Now!</p></div><div id="viewMore1f41bd0a4-e0ec-4521-860b-25fc88ab21f9" class="jsx-1189330088 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-1189330088"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-1189330088 button"></div></a><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-3134297187 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/a-tethered-approach-to-type-2-diabetes-care-connecting-insulin-regimens-with-digital-technology-cqdv?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-3134297187 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-3134297187 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F9f7ffzgm0g6g-ACP_TICatalog750x3612x.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F9f7ffzgm0g6g-ACP_TICatalog750x3612x.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F9f7ffzgm0g6g-ACP_TICatalog750x3612x.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-3134297187 bottomDiv"></div><div class="jsx-3134297187 border-div"></div><div class="jsx-3134297187 pill"></div><noscript class="jsx-3134297187">Video</noscript><noscript class="jsx-3134297187">CME,NCPD</noscript><div class="jsx-3134297187 content-wrap"><div class="jsx-3134297187 w-full h-fit mb-4"><p class="jsx-3134297187 text-xs px-4 text-center text-[#39485F] font-bold">A Tethered Approach to Type 2 Diabetes Care – Connecting Insulin Regimens with Digital Technology</p></div></div><div class="jsx-3134297187 view-more-wrap2d14e8a46-ff99-4fca-9bf9-6b93aaa75ac1"><div class="jsx-3134297187 flex justify-center w-[50%]"><p id="viewMoreText2d14e8a46-ff99-4fca-9bf9-6b93aaa75ac1" class="jsx-3134297187 text-sm text-[#ffffff]">View More</p></div><div id="viewMore2d14e8a46-ff99-4fca-9bf9-6b93aaa75ac1" class="jsx-3134297187 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-3134297187"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-3134297187 button"></div></a><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-3920454624 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/survey-says-what-are-clinicians-and-patients-saying-about-glucose-management-in-the-technology-age?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-3920454624 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-3920454624 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F0u97uvvry562-ACP_Survai_Archive_TICatalog750x361.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F0u97uvvry562-ACP_Survai_Archive_TICatalog750x361.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F0u97uvvry562-ACP_Survai_Archive_TICatalog750x361.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-3920454624 bottomDiv"></div><div class="jsx-3920454624 border-div"></div><div class="jsx-3920454624 pill"></div><noscript class="jsx-3920454624">Video</noscript><noscript class="jsx-3920454624">CME,NCPD</noscript><div class="jsx-3920454624 content-wrap"><div class="jsx-3920454624 w-full h-fit mb-4"><p class="jsx-3920454624 text-xs px-4 text-center text-[#39485F] font-bold">Surv.AI Says™: What Clinicians and Patients Are Saying About Glucose Management in the Technology Age</p></div></div><div class="jsx-3920454624 view-more-wrap32aef7e83-78fc-4ab5-9ee0-940bb46c07d0"><div class="jsx-3920454624 flex justify-center w-[50%]"><p id="viewMoreText32aef7e83-78fc-4ab5-9ee0-940bb46c07d0" class="jsx-3920454624 text-sm text-[#ffffff]">View More</p></div><div id="viewMore32aef7e83-78fc-4ab5-9ee0-940bb46c07d0" class="jsx-3920454624 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-3920454624"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-3920454624 button"></div></a><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-872076026 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/clinical-showcase-forming-a-personalized-treatment-plan-for-a-patient-with-anca-associated-vasculitis?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-872076026 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-872076026 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fj4x6y3g4v958-TICatalog750x3612x311.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fj4x6y3g4v958-TICatalog750x3612x311.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fj4x6y3g4v958-TICatalog750x3612x311.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-872076026 bottomDiv"></div><div class="jsx-872076026 border-div"></div><div class="jsx-872076026 pill"></div><noscript class="jsx-872076026">Case-based Simulation</noscript><noscript class="jsx-872076026">CME</noscript><div class="jsx-872076026 content-wrap"><div class="jsx-872076026 w-full h-fit mb-4"><p class="jsx-872076026 text-xs px-4 text-center text-[#39485F] font-bold">Clinical ShowCase™: Forming a Personalized Treatment Plan for a Patient With ANCA-Associated Vasculitis</p></div></div><div class="jsx-872076026 view-more-wrap4d6dcdce4-ecbe-4b82-9024-357b9b5a2318"><div class="jsx-872076026 flex justify-center w-[50%]"><p id="viewMoreText4d6dcdce4-ecbe-4b82-9024-357b9b5a2318" class="jsx-872076026 text-sm text-[#ffffff]">View More</p></div><div id="viewMore4d6dcdce4-ecbe-4b82-9024-357b9b5a2318" class="jsx-872076026 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-872076026"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-872076026 button"></div></a><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-4108833920 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/addressing-healthcare-inequities-tailoring-cancer-screening-plans-to-address-inequities-in-care?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-4108833920 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-4108833920 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fs3ftts655gmw-TICatalog750x3612x271.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fs3ftts655gmw-TICatalog750x3612x271.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fs3ftts655gmw-TICatalog750x3612x271.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-4108833920 bottomDiv"></div><div class="jsx-4108833920 border-div"></div><div class="jsx-4108833920 pill"></div><noscript class="jsx-4108833920">Video</noscript><noscript class="jsx-4108833920">CME,NCPD</noscript><div class="jsx-4108833920 content-wrap"><div class="jsx-4108833920 w-full h-fit mb-4"><p class="jsx-4108833920 text-xs px-4 text-center text-[#39485F] font-bold">Addressing Healthcare Inequities: Tailoring Cancer Screening Plans to Address Inequities in Care</p></div></div><div class="jsx-4108833920 view-more-wrap5724b2643-978e-4be0-9b3e-e15aacc39b41"><div class="jsx-4108833920 flex justify-center w-[50%]"><p id="viewMoreText5724b2643-978e-4be0-9b3e-e15aacc39b41" class="jsx-4108833920 text-sm text-[#ffffff]">View More</p></div><div id="viewMore5724b2643-978e-4be0-9b3e-e15aacc39b41" class="jsx-4108833920 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-4108833920"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-4108833920 button"></div></a><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-3236387575 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/patient-provider-caregiver-connection-understanding-the-patient-journey-to-provide-personalized-care-for-generalized-pustular-psoriasis?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-3236387575 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-3236387575 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F9ybisyhjkwg9-TICatalog750x3612x1212.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F9ybisyhjkwg9-TICatalog750x3612x1212.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2F9ybisyhjkwg9-TICatalog750x3612x1212.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-3236387575 bottomDiv"></div><div class="jsx-3236387575 border-div"></div><div class="jsx-3236387575 pill"></div><noscript class="jsx-3236387575">Video</noscript><noscript class="jsx-3236387575">CME,NCPD</noscript><div class="jsx-3236387575 content-wrap"><div class="jsx-3236387575 w-full h-fit mb-4"><p class="jsx-3236387575 text-xs px-4 text-center text-[#39485F] font-bold">Patient, Provider & Caregiver Connection™: Understanding the Patient Journey to Provide Personalized Care for Generalized Pustular Psoriasis</p></div></div><div class="jsx-3236387575 view-more-wrap67c9c5349-b821-419d-8155-ac71d963bb15"><div class="jsx-3236387575 flex justify-center w-[50%]"><p id="viewMoreText67c9c5349-b821-419d-8155-ac71d963bb15" class="jsx-3236387575 text-sm text-[#ffffff]">View More</p></div><div id="viewMore67c9c5349-b821-419d-8155-ac71d963bb15" class="jsx-3236387575 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-3236387575"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-3236387575 button"></div></a><a target="_blank" style="scroll-snap-align:center;text-decoration:none" class="jsx-3159401139 w-[250px] h-[350px] flex flex-col space-y-3 flex-none select-none no-underline" href="https://www.gotoper.com/courses/cases-and-conversations-applying-best-practices-to-prevent-shingles-in-your-practice-x7ap?utm_source=hcplive&utm_medium=homePage&utm_campaign=cmeDeck"><div class="jsx-3159401139 w-full h-full flex flex-col rounded-b-[10px] rounded-t-[15px] overflow-hidden relative bg-white shadow-[0_3px_7px_0px_#37393d]"><div class="jsx-3159401139 relative rounded-t-[15px]"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27250%27%20height=%27125%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill"/><noscript><img alt="" srcSet="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fk7tj8wih6443-TICatalog750x3612x491.png&w=256&q=75 1x, /_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fk7tj8wih6443-TICatalog750x3612x491.png&w=640&q=75 2x" src="/_next/image?url=https%3A%2F%2Fd36ai2hkxl16us.cloudfront.net%2Fthoughtindustries%2Fimage%2Fupload%2Fv1%2Fcourse-uploads%2F07c0d4e1-23aa-4e1a-8c5f-f2569da581c0%2Fk7tj8wih6443-TICatalog750x3612x491.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%;object-fit:fill" loading="lazy"/></noscript></span></div><div class="jsx-3159401139 bottomDiv"></div><div class="jsx-3159401139 border-div"></div><div class="jsx-3159401139 pill"></div><noscript class="jsx-3159401139">Video</noscript><noscript class="jsx-3159401139">CME,NCPD</noscript><div class="jsx-3159401139 content-wrap"><div class="jsx-3159401139 w-full h-fit mb-4"><p class="jsx-3159401139 text-xs px-4 text-center text-[#39485F] font-bold">Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice</p></div></div><div class="jsx-3159401139 view-more-wrap778417c0d-8dcf-4912-9555-8f4660d32529"><div class="jsx-3159401139 flex justify-center w-[50%]"><p id="viewMoreText778417c0d-8dcf-4912-9555-8f4660d32529" class="jsx-3159401139 text-sm text-[#ffffff]">View More</p></div><div id="viewMore778417c0d-8dcf-4912-9555-8f4660d32529" class="jsx-3159401139 flex w-[15%] h-full justify-center items-center bg-secondary z-[9999]"><div class="jsx-3159401139"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" style="color:var(--primary);width:100%;height:100%" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1 8a.5.5 0 0 1 .5-.5h11.793l-3.147-3.146a.5.5 0 0 1 .708-.708l4 4a.5.5 0 0 1 0 .708l-4 4a.5.5 0 0 1-.708-.708L13.293 8.5H1.5A.5.5 0 0 1 1 8z"></path></svg></div></div></div></div><div class="jsx-3159401139 button"></div></a></div></div><div class="m-2"><h2 class="text-3xl">All News</h2><div class="w-full border border-secondary"></div><div class="grid gap-2 md:gap-4 grid-cols-1"><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/tapinarof-consistent-efficacy-across-body-regions-ad"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:106.70553935860059%"></span><img alt="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" title="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" title="Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Ff5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/tapinarof-consistent-efficacy-across-body-regions-ad">Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span></div><a href="/view/tapinarof-consistent-efficacy-across-body-regions-ad"><span class="text-sm text-gray-500">February 21st 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">In new data to be presented at AAAAI, the therapy was well-tolerated in people as young as 2 years old.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/rates-of-iron-deficiency-differ-by-clinical-definition-in-heart-failure"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure | Image Credit: Medical University of Innsbruck" title="Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure | Image Credit: Medical University of Innsbruck" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure | Image Credit: Medical University of Innsbruck" title="Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure | Image Credit: Medical University of Innsbruck" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8ed591956c6daeac8382b305046f918b710e3764-600x600.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/rates-of-iron-deficiency-differ-by-clinical-definition-in-heart-failure">Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/connor-iapoce">Connor Iapoce</a></span></div><a href="/view/rates-of-iron-deficiency-differ-by-clinical-definition-in-heart-failure"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Iron deficiency was more common in acute versus chronic heart failure, with notable differences in detection by numerous recommended definitions. </p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/pediatric-atopic-dermatitis-most-effectively-treated-upadacitinib-study-finds"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds" title="Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds" title="Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/pediatric-atopic-dermatitis-most-effectively-treated-upadacitinib-study-finds">Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/tim-smith">Tim Smith</a></span></div><a href="/view/pediatric-atopic-dermatitis-most-effectively-treated-upadacitinib-study-finds"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">These data were the result of a new network meta-analysis looking specifically at children with eczema, highlighting the hierarchy of effectiveness among systemic drugs.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/expert-panel-develops-consensus-definition-clinical-tool-anaphylaxis-care"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:122.84482758620689%"></span><img alt="Timothy E. Dribin, MD I Credit: Cincinnati Children’s Hospital Medical Center" title="Timothy E. Dribin, MD I Credit: Cincinnati Children’s Hospital Medical Center" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Timothy E. Dribin, MD I Credit: Cincinnati Children’s Hospital Medical Center" title="Timothy E. Dribin, MD I Credit: Cincinnati Children’s Hospital Medical Center" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F30d5991e9fd90975f8abee94b079a38f5da712c1-464x570.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/expert-panel-develops-consensus-definition-clinical-tool-anaphylaxis-care">Expert Panel Develops Consensus Definition, Clinical Tool for Anaphylaxis Care</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/chelsie-derman">Chelsie Derman</a></span></div><a href="/view/expert-panel-develops-consensus-definition-clinical-tool-anaphylaxis-care"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">A 46-member expert panel created a consensus anaphylaxis definition, overview, and clinical tool to aid clinicians in recognition and management across settings.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/clinical-quiz-clinical-considerations-food-allergy-prevention"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100.42735042735043%"></span><img alt="Clinical Quiz: Dietary Diversity and Allergy Prevention" title="Clinical Quiz: Dietary Diversity and Allergy Prevention" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Clinical Quiz: Dietary Diversity and Allergy Prevention" title="Clinical Quiz: Dietary Diversity and Allergy Prevention" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/clinical-quiz-clinical-considerations-food-allergy-prevention">Clinical Quiz: Clinical Considerations in Food Allergy Prevention</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/hcplive-editorial-staff">HCPLive Editorial Staff</a></span></div><a href="/view/clinical-quiz-clinical-considerations-food-allergy-prevention"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">In this quiz, we test your knowledge of recommendations to prevent food allergy development in infants.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/add-on-remibrutinib-quickly-improves-urticaria-control-csu"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" title="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" title="Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450.tif%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/add-on-remibrutinib-quickly-improves-urticaria-control-csu">Add-on Remibrutinib Quickly Improves Urticaria Control in CSU</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span></div><a href="/view/add-on-remibrutinib-quickly-improves-urticaria-control-csu"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">By week 52, remibrutinib and placebo-to-remibrutinib groups had similar levels of urticaria control.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/second-trimester-kidney-function-linked-adverse-pregnancy-outcomes"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Anika Lucas, MD | Credit: Duke University School of Medicine" title="Anika Lucas, MD | Credit: Duke University School of Medicine" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Anika Lucas, MD | Credit: Duke University School of Medicine" title="Anika Lucas, MD | Credit: Duke University School of Medicine" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F5f150b703174f7bda1b31493a017d41e551e30e1-872x872.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/second-trimester-kidney-function-linked-adverse-pregnancy-outcomes">Second Trimester Kidney Function Linked to Adverse Pregnancy Outcomes</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/abigail-brooks">Abigail Brooks, MA</a></span></div><a href="/view/second-trimester-kidney-function-linked-adverse-pregnancy-outcomes"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Low and high second-trimester eGFR values were linked to adverse pregnancy outcomes, including preeclampsia, preterm birth, low birth weight, and fetal loss.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" title="Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" title="Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md">Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/w-lloyd-clark-md">W. Lloyd Clark, MD</a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/connor-iapoce">Connor Iapoce</a></span></div><a href="/view/aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Clark describes visual and anatomic improvements with aflibercept 8 mg in the PULSAR extension study, with most patients achieving extended dosing regimens.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/spn-820-fails-phase-2b-trial-treatment-resistant-depression"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:66.36971046770601%"></span><img alt="Credit: Adobe Stock/ Africa Studio" title="Credit: Adobe Stock/ Africa Studio" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Credit: Adobe Stock/ Africa Studio" title="Credit: Adobe Stock/ Africa Studio" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fbecc697436f8df85ec87549ea9ae200ba56682a3-898x596.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/spn-820-fails-phase-2b-trial-treatment-resistant-depression">SPN-820 Fails Phase 2b Trial for Treatment-Resistant Depression</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/chelsie-derman">Chelsie Derman</a></span></div><a href="/view/spn-820-fails-phase-2b-trial-treatment-resistant-depression"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">A phase 2b trial showed that, unlike patients with MDD, patients with treatment-resistant depression do not receive significant benefits from SPN-820.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/fda-clears-ind-application-zabalafin-hydrogel-treatment-of-atopic-dermatitis"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis " title="FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis " src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis " title="FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis " sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/fda-clears-ind-application-zabalafin-hydrogel-treatment-of-atopic-dermatitis">FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis </a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/tim-smith">Tim Smith</a></span></div><a href="/view/fda-clears-ind-application-zabalafin-hydrogel-treatment-of-atopic-dermatitis"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Alpyn’s Investigational New Drug application’s clearance by the FDA for the new Zabalafin Hydrogel for atopic dermatitis follows positive phase 2a clinical findings.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/gene-interaction-increases-patients-risk-of-frontal-fibrosing-alopecia"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia" title="Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia" title="Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe6192a743ebd63874848e078b799f6de2e899ae0-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/gene-interaction-increases-patients-risk-of-frontal-fibrosing-alopecia">Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/tim-smith">Tim Smith</a></span></div><a href="/view/gene-interaction-increases-patients-risk-of-frontal-fibrosing-alopecia"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">This genome-wide meta-analysis demonstrated that changes in 2 parts of the genome both work to influence patients’ risk of frontal fibrosing alopecia (FFA).</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/how-btk-inhibitors-differ-from-current-csu-treatment-approaches"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:56.25%"></span><img alt="How BTK Inhibitors Differ From Current CSU Treatment Approaches" title="How BTK Inhibitors Differ From Current CSU Treatment Approaches" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="How BTK Inhibitors Differ From Current CSU Treatment Approaches" title="How BTK Inhibitors Differ From Current CSU Treatment Approaches" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/how-btk-inhibitors-differ-from-current-csu-treatment-approaches">How BTK Inhibitors Differ From Current CSU Treatment Approaches</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/giselle-mosnaim-md-ms">Giselle Mosnaim, MD, MS </a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/shyam-joshi-md">Shyam Joshi, MD </a></span><div class="relative group w-3"><button><svg stroke="currentColor" fill="none" stroke-width="2" viewBox="0 0 24 24" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path stroke-linecap="round" stroke-linejoin="round" d="M5 12h.01M12 12h.01M19 12h.01M6 12a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0z"></path></svg></button><div class="absolute hidden w-[280px] top-0 flex flex-col mt-6 group-hover:flex"><div class="w-3 h-3 -mb-2 rotate-45 bg-[#eee] ml-[2px]"></div><span class="relative z-10 p-2 text-xs leading-none whitespace-no-wrap bg-[#eee] shadow-lg"><ul><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/mark-lebwohl-md">Mark Lebwohl, MD</a></li><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/jason-hawkes-md-ms">Jason Hawkes, MD, MS</a></li></ul></span></div></div></div><a href="/view/how-btk-inhibitors-differ-from-current-csu-treatment-approaches"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Panelists discuss how Bruton tyrosine kinase (BTK) inhibitors offer a novel upstream approach, in contrast to current treatments that work downstream by either blocking released mediators (antihistamines), neutralizing circulating IgE (omalizumab), or broadly suppressing immune responses (immunosuppressants).</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/btk-inhibition-as-a-strategy-for-csu-treatment"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:56.25%"></span><img alt="BTK Inhibition as a Strategy for CSU Treatment" title="BTK Inhibition as a Strategy for CSU Treatment" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="BTK Inhibition as a Strategy for CSU Treatment" title="BTK Inhibition as a Strategy for CSU Treatment" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/btk-inhibition-as-a-strategy-for-csu-treatment">BTK Inhibition as a Strategy for CSU Treatment</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/giselle-mosnaim-md-ms">Giselle Mosnaim, MD, MS </a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/shyam-joshi-md">Shyam Joshi, MD </a></span><div class="relative group w-3"><button><svg stroke="currentColor" fill="none" stroke-width="2" viewBox="0 0 24 24" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path stroke-linecap="round" stroke-linejoin="round" d="M5 12h.01M12 12h.01M19 12h.01M6 12a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0z"></path></svg></button><div class="absolute hidden w-[280px] top-0 flex flex-col mt-6 group-hover:flex"><div class="w-3 h-3 -mb-2 rotate-45 bg-[#eee] ml-[2px]"></div><span class="relative z-10 p-2 text-xs leading-none whitespace-no-wrap bg-[#eee] shadow-lg"><ul><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/mark-lebwohl-md">Mark Lebwohl, MD</a></li><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/jason-hawkes-md-ms">Jason Hawkes, MD, MS</a></li></ul></span></div></div></div><a href="/view/btk-inhibition-as-a-strategy-for-csu-treatment"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Panelists discuss how Bruton tyrosine kinase (BTK) inhibition could effectively treat both autoallergic and autoimmune chronic spontaneous urticaria (CSU).</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/multidisciplinary-care-model-improves-liver-metabolic-outcomes-mash"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Jonathan Stine, MD, MSc | Credit: Penn State Health" title="Jonathan Stine, MD, MSc | Credit: Penn State Health" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Jonathan Stine, MD, MSc | Credit: Penn State Health" title="Jonathan Stine, MD, MSc | Credit: Penn State Health" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fe9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/multidisciplinary-care-model-improves-liver-metabolic-outcomes-mash">Multidisciplinary Care Model Improves Liver, Metabolic Outcomes in MASH</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/abigail-brooks">Abigail Brooks, MA</a></span></div><a href="/view/multidisciplinary-care-model-improves-liver-metabolic-outcomes-mash"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">The multidisciplinary care model included 7 co-located specialists who aided patient education, lifestyle intervention, and drug therapy strategies for MASH.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/investigating-brensocatib-first-treatment-bronchiectasis-chalmers"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD" title="Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD" title="Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/investigating-brensocatib-first-treatment-bronchiectasis-chalmers">Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/james-chalmers-mbchb-phd">James Chalmers, MBChB, PhD</a></span></div><a href="/view/investigating-brensocatib-first-treatment-bronchiectasis-chalmers"><span class="text-sm text-gray-500">February 20th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Chalmers discussed how brensocatib’s potential approval may transform the currently empty treatment landscape for bronchiectasis.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" title="Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" title="Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md">Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/w-lloyd-clark-md">W. Lloyd Clark, MD</a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/connor-iapoce">Connor Iapoce</a></span></div><a href="/view/aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><div class="py-1 text-sm text-gray-500"><div class="blockText_blockContent__TbCXh"></div></div></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/ai-in-dermatology-emerging-insights-and-diverging-perspectives"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="AI in Dermatology: Emerging Insights and Diverging Perspectives" title="AI in Dermatology: Emerging Insights and Diverging Perspectives" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="AI in Dermatology: Emerging Insights and Diverging Perspectives" title="AI in Dermatology: Emerging Insights and Diverging Perspectives" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/ai-in-dermatology-emerging-insights-and-diverging-perspectives">AI in Dermatology: Emerging Insights and Diverging Perspectives</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/tim-smith">Tim Smith</a></span><span class="text-md "><span class="mr-1 italic"><br/></span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/shuai-steve-xu-md-msc-">Shuai (Steve) Xu, MD, MSc,</a></span><div class="relative group w-3"><button><svg stroke="currentColor" fill="none" stroke-width="2" viewBox="0 0 24 24" aria-hidden="true" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path stroke-linecap="round" stroke-linejoin="round" d="M5 12h.01M12 12h.01M19 12h.01M6 12a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0zm7 0a1 1 0 11-2 0 1 1 0 012 0z"></path></svg></button><div class="absolute hidden w-[280px] top-0 flex flex-col mt-6 group-hover:flex"><div class="w-3 h-3 -mb-2 rotate-45 bg-[#eee] ml-[2px]"></div><span class="relative z-10 p-2 text-xs leading-none whitespace-no-wrap bg-[#eee] shadow-lg"><ul><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/kailas-vodrahalli">Kailas Vodrahalli</a></li><li class="pb-2"><a class="mr-1 text-sm text-sky-800 hover:text-primary" href="/authors/harald-kittler-md">Harald Kittler, MD</a></li></ul></span></div></div></div><a href="/view/ai-in-dermatology-emerging-insights-and-diverging-perspectives"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">In this feature, 3 experts highlight their own research on new technological advances and their views on the benefits and drawbacks of artificial intelligence in dermatology.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/clinical-quiz-dietary-diversity-allergy-prevention"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100.42735042735043%"></span><img alt="Clinical Quiz: Dietary Diversity and Allergy Prevention" title="Clinical Quiz: Dietary Diversity and Allergy Prevention" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Clinical Quiz: Dietary Diversity and Allergy Prevention" title="Clinical Quiz: Dietary Diversity and Allergy Prevention" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/clinical-quiz-dietary-diversity-allergy-prevention">Clinical Quiz: Dietary Diversity and Allergy Prevention</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/hcplive-editorial-staff">HCPLive Editorial Staff</a></span></div><a href="/view/clinical-quiz-dietary-diversity-allergy-prevention"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">In this quiz, we test your knowledge of recommendations for introducing dietary diversity to infants.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/sozinibercept-topline-results-expected-in-q2-after-coast-trial-completion"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Sozinibercept Topline Results Expected in Q2 After COAST Trial Completion| Image Credit: Opthea" title="Sozinibercept Topline Results Expected in Q2 After COAST Trial Completion| Image Credit: Opthea" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Sozinibercept Topline Results Expected in Q2 After COAST Trial Completion| Image Credit: Opthea" title="Sozinibercept Topline Results Expected in Q2 After COAST Trial Completion| Image Credit: Opthea" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/sozinibercept-topline-results-expected-in-q2-after-coast-trial-completion">Sozinibercept Topline Results Expected in Q2 After COAST Trial Completion</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/connor-iapoce">Connor Iapoce</a></span></div><a href="/view/sozinibercept-topline-results-expected-in-q2-after-coast-trial-completion"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">The first of two Phase 3 pivotal trials investigating sozinibercept, COAST completed its final week 52 visit in patients with wet AMD.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/amneal-launches-mesalamine-ulcerative-colitis-receives-lenalidomide-fda-approval"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="FDA black and white logo | Credit: US Food and Drug Administration" title="FDA black and white logo | Credit: US Food and Drug Administration" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="FDA black and white logo | Credit: US Food and Drug Administration" title="FDA black and white logo | Credit: US Food and Drug Administration" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/amneal-launches-mesalamine-ulcerative-colitis-receives-lenalidomide-fda-approval">Amneal Launches Mesalamine for Ulcerative Colitis, Receives Lenalidomide FDA Approval</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/abigail-brooks">Abigail Brooks, MA</a></span></div><a href="/view/amneal-launches-mesalamine-ulcerative-colitis-receives-lenalidomide-fda-approval"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Amneal Pharmaceuticals launched mesalamine 800 mg delayed-release tablets for UC and received FDA approval for various lenalidomide doses for blood cancers.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/major-risk-factors-identified-which-may-limit-oral-jak-inhibitor-use-in-hs"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Major Risk Factors Identified Which May Limit Oral JAK Inhibitor Use in HS" title="Major Risk Factors Identified Which May Limit Oral JAK Inhibitor Use in HS" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Major Risk Factors Identified Which May Limit Oral JAK Inhibitor Use in HS" title="Major Risk Factors Identified Which May Limit Oral JAK Inhibitor Use in HS" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1b7255c8e81631df3248c7cd37895578f2a880a3-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/major-risk-factors-identified-which-may-limit-oral-jak-inhibitor-use-in-hs">Major Risk Factors Identified Which May Limit Oral JAK Inhibitor Use in HS</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/tim-smith">Tim Smith</a></span></div><a href="/view/major-risk-factors-identified-which-may-limit-oral-jak-inhibitor-use-in-hs"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">This analysis highlights the major risk factors resulting in limited use of oral JAKi for patients with hidradenitis suppurativa, including smoking, obesity, hypertension, and age.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/fda-rejects-pitolisant-nda-idiopathic-hypersomnia"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia" title="FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia" title="FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2Fc19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/fda-rejects-pitolisant-nda-idiopathic-hypersomnia">FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span></div><a href="/view/fda-rejects-pitolisant-nda-idiopathic-hypersomnia"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Pitolisant was evaluated for the supplemental indication in the phase 3 INTUNE study, which did not meet its primary outcome of reducing excessive daytime sleepiness.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/nebokitug-cm-101-gets-fda-runway-psc-approval"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="FDA black and white logo | Credit: US Food and Drug Administration" title="FDA black and white logo | Credit: US Food and Drug Administration" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="FDA black and white logo | Credit: US Food and Drug Administration" title="FDA black and white logo | Credit: US Food and Drug Administration" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400.webp%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/nebokitug-cm-101-gets-fda-runway-psc-approval">Nebokitug (CM-101) Gets FDA Runway for PSC Approval</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/abigail-brooks">Abigail Brooks, MA</a></span></div><a href="/view/nebokitug-cm-101-gets-fda-runway-psc-approval"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Chemomab completed an end-of-phase 2 meeting with the FDA and has aligned on the design of a phase 3 registration study for nebokitug (CM-101) in PSC.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/hdv-rna-positivity-linked-greater-risk-severe-liver-related-outcomes"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:99.6005326231691%"></span><img alt="Thomas Vanwolleghem, MD, PhD | Credit: Thomas Vanwolleghem on LinkedIn" title="Thomas Vanwolleghem, MD, PhD | Credit: Thomas Vanwolleghem on LinkedIn" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Thomas Vanwolleghem, MD, PhD | Credit: Thomas Vanwolleghem on LinkedIn" title="Thomas Vanwolleghem, MD, PhD | Credit: Thomas Vanwolleghem on LinkedIn" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748.png%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/hdv-rna-positivity-linked-greater-risk-severe-liver-related-outcomes">HDV RNA Positivity Linked to Greater Risk of Severe Liver-Related Outcomes</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/abigail-brooks">Abigail Brooks, MA</a></span></div><a href="/view/hdv-rna-positivity-linked-greater-risk-severe-liver-related-outcomes"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">HDV RNA-positive patients were more often diagnosed with advanced liver fibrosis and had a 4.7-fold greater risk of severe liver-related outcomes.</p></a><div class="flex mt-4"></div></div></div></div><div class="w-full h-full"><div class="flex mt-4"><a class="w-full mt-3 md:flex-none md:w-48" href="/view/ruxolitinib-clinical-benefit-children-adults-atopic-dermatitis"><div class=""><span style="box-sizing:border-box;display:block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;padding-top:100%"></span><img alt="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" title="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="responsive" class="shrink-0" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" title="Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health & Science University" sizes="100vw" srcSet="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=640&q=75 640w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=750&q=75 750w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=828&q=75 828w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1080&q=75 1080w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1200&q=75 1200w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=1920&q=75 1920w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=2048&q=75 2048w, /_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75 3840w" src="/_next/image?url=https%3A%2F%2Fcdn.sanity.io%2Fimages%2F0vv8moc6%2Fhcplive%2F1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300.jpg%3Ffit%3Dcrop%26auto%3Dformat&w=3840&q=75" decoding="async" data-nimg="responsive" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" class="shrink-0" loading="lazy"/></noscript></span></div></a><div class="w-[200%] md:w-[auto] flex-auto p-2 ml-2"><p class="font-bold"><a class="" href="/view/ruxolitinib-clinical-benefit-children-adults-atopic-dermatitis">Ruxolitinib Shows Clinical Benefit in Children, Adults With Atopic Dermatitis</a></p><div><span class="text-md "><span class="mr-1 italic">By </span><a class="mr-1 text-sky-800 hover:text-primary" href="/authors/victoria-johnson">Victoria Johnson</a></span></div><a href="/view/ruxolitinib-clinical-benefit-children-adults-atopic-dermatitis"><span class="text-sm text-gray-500">February 19th 2025</span><div class="mt-2"></div><p class="mt-4 text-gray-800">Data from 3 pooled phase 3 studies in children, adolescents, and adults will be presented at the AAAI/WAO Joint Congress.</p></a><div class="flex mt-4"></div></div></div></div></div><div class="text-center w-full pt-4 text-2xl font-bold pb-24"><a class="text-lg hover:text-gray-400 hover:underline" href="/news">See All News ></a></div></div></div><div class="flex-none w-[300px] z-[9999] relative hidden md:block"><div style="top:7rem" class="sticky custom-spacing"><div class="collapse-container " style="overflow:hidden;max-height:900px;transition:max-height .4s ease-in-out"></div></div></div></div><div id="div-gpt-ad-pixel" style="width:1px;height:1px" class=""></div><noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-KNMGBBN" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript><div id="footerOuterWrap" class="w-full bg-primary flex flex-col items-center justify-center"><div class="container w-[1340px]"><div id="footerInnerWrap" class="bg-primary w-full py-12"><div class="py-4 pl-4 flex flex-row items-center"><div class="flex flex-row flex-wrap w-[55%] h-full"><div class="w-[33%] p-1 my-0 cursor-pointer text-footer-text-color hover:text-footer-text-color/80 hover:underline"><a class="text-md" target="_self" href="/about">About Us</a></div><div class="w-[33%] p-1 my-0 cursor-pointer text-footer-text-color hover:text-footer-text-color/80 hover:underline"><a class="text-md" target="_self" href="/advertise">Advertise</a></div><div class="w-[33%] p-1 my-0 cursor-pointer text-footer-text-color hover:text-footer-text-color/80 hover:underline"><a class="text-md" target="_self" href="/editorial">Editorial</a></div><div class="w-[33%] p-1 my-0 cursor-pointer text-footer-text-color hover:text-footer-text-color/80 hover:underline"><a class="text-md" target="_self" href="/contact-us">Contact Us</a></div><div class="w-[33%] p-1 my-0 cursor-pointer text-footer-text-color hover:text-footer-text-color/80 hover:underline"><a class="text-md" target="_blank" href="https://www.mjhlifesciences.com/ccpa?domain=www.hcplive.com">Do Not Sell My Information</a></div><div class="w-[33%] p-1 my-0 cursor-pointer text-footer-text-color hover:text-footer-text-color/80 hover:underline"><a class="text-md" target="_blank" href="/privacy">Privacy</a></div><div class="w-[33%] p-1 my-0 cursor-pointer text-footer-text-color hover:text-footer-text-color/80 hover:underline"><a class="text-md" target="_blank" href="/terms">Terms & Conditions</a></div></div><div class="w-[45%] flex flex-row"><div class="w-[1px] bg-footer-vertical-rule"></div><div class="text-center flex w-[50%] flex-col gap-4 px-8 text-footer-text-color"><div class="py-2 text-xl">Contact Info</div><div class="mx-auto"><div class="flex flex-row gap-4 mb-4"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 24 24" class="text-footer-icon-color" font-size="30" style="margin-top:0.2rem" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill="none" d="M0 0h24v24H0z"></path><path d="M12 2C8.13 2 5 5.13 5 9c0 1.74.5 3.37 1.41 4.84.95 1.54 2.2 2.86 3.16 4.4.47.75.81 1.45 1.17 2.26.26.55.47 1.5 1.26 1.5s1-.95 1.25-1.5c.37-.81.7-1.51 1.17-2.26.96-1.53 2.21-2.85 3.16-4.4C18.5 12.37 19 10.74 19 9c0-3.87-3.13-7-7-7zm0 9.75a2.5 2.5 0 010-5 2.5 2.5 0 010 5z"></path></svg><p class="text-left text-sm">2 Commerce Drive <br/>Cranbury, NJ 08512</p></div><div class="flex flex-row gap-4 mb-4"><svg stroke="currentColor" fill="currentColor" stroke-width="0" viewBox="0 0 16 16" class="text-footer-icon-color ml-2" font-size="25" height="1em" width="1em" xmlns="http://www.w3.org/2000/svg"><path fill-rule="evenodd" d="M1.885.511a1.745 1.745 0 0 1 2.61.163L6.29 2.98c.329.423.445.974.315 1.494l-.547 2.19a.678.678 0 0 0 .178.643l2.457 2.457a.678.678 0 0 0 .644.178l2.189-.547a1.745 1.745 0 0 1 1.494.315l2.306 1.794c.829.645.905 1.87.163 2.611l-1.034 1.034c-.74.74-1.846 1.065-2.877.702a18.634 18.634 0 0 1-7.01-4.42 18.634 18.634 0 0 1-4.42-7.009c-.362-1.03-.037-2.137.703-2.877L1.885.511z"></path></svg><p class="text-sm"><a href="tel:609-716-7777">609-716-7777</a></p></div></div></div><div class="w-[1px] bg-footer-vertical-rule"></div><div class="flex flex-col gap-8 items-center justify-center" style="margin:0 auto"><span style="box-sizing:border-box;display:inline-block;overflow:hidden;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;position:relative;max-width:100%"><span style="box-sizing:border-box;display:block;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0;max-width:100%"><img style="display:block;max-width:100%;width:initial;height:initial;background:none;opacity:1;border:0;margin:0;padding:0" alt="" aria-hidden="true" src="data:image/svg+xml,%3csvg%20xmlns=%27http://www.w3.org/2000/svg%27%20version=%271.1%27%20width=%27200%27%20height=%2733%27/%3e"/></span><img alt="" src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%"/><noscript><img alt="" srcSet="/_next/image?url=%2Fan_mjhls_brand_ko.png&w=256&q=75 1x, /_next/image?url=%2Fan_mjhls_brand_ko.png&w=640&q=75 2x" src="/_next/image?url=%2Fan_mjhls_brand_ko.png&w=640&q=75" decoding="async" data-nimg="intrinsic" style="position:absolute;top:0;left:0;bottom:0;right:0;box-sizing:border-box;padding:0;border:none;margin:auto;display:block;width:0;height:0;min-width:100%;max-width:100%;min-height:100%;max-height:100%" loading="lazy"/></noscript></span><div class="flex flex-wrap self-start pt-6 pl-2"><a href="https://www.facebook.com/HCPLiveNews/" class="social-icon mx-0.5 mb-1" target="_blank" rel="noopener noreferrer" style="display:inline-block;width:30px;height:30px;position:relative;overflow:hidden;vertical-align:middle" aria-label="facebook"><span class="social-container" style="position:absolute;top:0;left:0;width:100%;height:100%"><svg role="img" aria-label="facebook social icon" class="social-svg" viewBox="0 0 64 64" style="position:absolute;top:0;left:0;width:100%;height:100%;border-radius:50%;fill-rule:evenodd"><g class="social-svg-icon" style="transition:fill 170ms ease-in-out;fill:white"><path d="M0,0H64V64H0ZM0 0v64h64V0zm39.6 22h-2.8c-2.2 0-2.6 1.1-2.6 2.6V28h5.3l-.7 5.3h-4.6V47h-5.5V33.3H24V28h4.6v-4c0-4.6 2.8-7 6.9-7 2 0 3.6.1 4.1.2z"></path></g><g class="social-svg-mask" style="transition:fill 170ms ease-in-out;fill:#3b5998"><path d="M0 0v64h64V0zm39.6 22h-2.8c-2.2 0-2.6 1.1-2.6 2.6V28h5.3l-.7 5.3h-4.6V47h-5.5V33.3H24V28h4.6v-4c0-4.6 2.8-7 6.9-7 2 0 3.6.1 4.1.2z"></path></g></svg></span></a><a href="https://twitter.com/HCPLiveNews " class="social-icon mx-0.5 mb-1" target="_blank" rel="noopener noreferrer" style="display:inline-block;width:30px;height:30px;position:relative;overflow:hidden;vertical-align:middle" aria-label="x"><span class="social-container" style="position:absolute;top:0;left:0;width:100%;height:100%"><svg role="img" aria-label="x social icon" class="social-svg" viewBox="0 0 64 64" style="position:absolute;top:0;left:0;width:100%;height:100%;border-radius:50%;fill-rule:evenodd"><g class="social-svg-icon" style="transition:fill 170ms ease-in-out;fill:white"><path d="M0,0H64V64H0ZM0 0v64h64V0zm16 17.537h10.125l6.992 9.242 8.084-9.242h4.908L35.39 29.79 48 46.463h-9.875l-7.734-10.111-8.85 10.11h-4.908l11.465-13.105zm5.73 2.783 17.75 23.205h2.72L24.647 20.32z"></path></g><g class="social-svg-mask" style="transition:fill 170ms ease-in-out;fill:#000000"><path d="M0 0v64h64V0zm16 17.537h10.125l6.992 9.242 8.084-9.242h4.908L35.39 29.79 48 46.463h-9.875l-7.734-10.111-8.85 10.11h-4.908l11.465-13.105zm5.73 2.783 17.75 23.205h2.72L24.647 20.32z"></path></g></svg></span></a><a href="https://www.linkedin.com/company/hcplive" class="social-icon mx-0.5 mb-1" target="_blank" rel="noopener noreferrer" style="display:inline-block;width:30px;height:30px;position:relative;overflow:hidden;vertical-align:middle" aria-label="linkedin"><span class="social-container" style="position:absolute;top:0;left:0;width:100%;height:100%"><svg role="img" aria-label="linkedin social icon" class="social-svg" viewBox="0 0 64 64" style="position:absolute;top:0;left:0;width:100%;height:100%;border-radius:50%;fill-rule:evenodd"><g class="social-svg-icon" style="transition:fill 170ms ease-in-out;fill:white"><path d="M0,0H64V64H0ZM0 0v64h64V0zm25.8 44h-5.4V26.6h5.4zm-2.7-19.7c-1.7 0-3.1-1.4-3.1-3.1s1.4-3.1 3.1-3.1 3.1 1.4 3.1 3.1-1.4 3.1-3.1 3.1M46 44h-5.4v-8.4c0-2 0-4.6-2.8-4.6s-3.2 2.2-3.2 4.5V44h-5.4V26.6h5.2V29h.1c.7-1.4 2.5-2.8 5.1-2.8 5.5 0 6.5 3.6 6.5 8.3V44z"></path></g><g class="social-svg-mask" style="transition:fill 170ms ease-in-out;fill:#007fb1"><path d="M0 0v64h64V0zm25.8 44h-5.4V26.6h5.4zm-2.7-19.7c-1.7 0-3.1-1.4-3.1-3.1s1.4-3.1 3.1-3.1 3.1 1.4 3.1 3.1-1.4 3.1-3.1 3.1M46 44h-5.4v-8.4c0-2 0-4.6-2.8-4.6s-3.2 2.2-3.2 4.5V44h-5.4V26.6h5.2V29h.1c.7-1.4 2.5-2.8 5.1-2.8 5.5 0 6.5 3.6 6.5 8.3V44z"></path></g></svg></span></a><a href="/rss" class="social-icon mx-0.5 mb-1" target="_self" rel="noopener noreferrer" style="display:inline-block;width:30px;height:30px;position:relative;overflow:hidden;vertical-align:middle" aria-label="rss"><span class="social-container" style="position:absolute;top:0;left:0;width:100%;height:100%"><svg role="img" aria-label="rss social icon" class="social-svg" viewBox="0 0 64 64" style="position:absolute;top:0;left:0;width:100%;height:100%;border-radius:50%;fill-rule:evenodd"><g class="social-svg-icon" style="transition:fill 170ms ease-in-out;fill:white"><path d="M0,0H64V64H0ZM0 0v64h64V0zm24 44c-2.2 0-4-1.8-4-4s1.8-4 4-4 4 1.8 4 4-1.8 4-4 4m11-1c-1.1 0-2-.9-2-2 0-5.5-4.5-10-10-10-1.1 0-2-.9-2-2s.9-2 2-2c7.7 0 14 6.3 14 14 0 1.1-.9 2-2 2m9 0c-1.1 0-2-.9-2-2 0-10.5-8.5-19-19-19-1.1 0-2-.9-2-2s.9-2 2-2c12.7 0 23 10.3 23 23 0 1.1-.9 2-2 2"></path></g><g class="social-svg-mask" style="transition:fill 170ms ease-in-out;fill:#EF8733"><path d="M0 0v64h64V0zm24 44c-2.2 0-4-1.8-4-4s1.8-4 4-4 4 1.8 4 4-1.8 4-4 4m11-1c-1.1 0-2-.9-2-2 0-5.5-4.5-10-10-10-1.1 0-2-.9-2-2s.9-2 2-2c7.7 0 14 6.3 14 14 0 1.1-.9 2-2 2m9 0c-1.1 0-2-.9-2-2 0-10.5-8.5-19-19-19-1.1 0-2-.9-2-2s.9-2 2-2c12.7 0 23 10.3 23 23 0 1.1-.9 2-2 2"></path></g></svg></span></a></div></div></div></div></div></div><div class="w-full bg-secondary flex justify-center"><div class="bg-secondary w-[85%] text-subfooter-text-color text-sm font-bold"><div class="flex flex-col gap-8 md:flex-row justify-between p-4 md:py-4 md:px-12"><div>© 2025 MJH Life Sciences <br/> <br/> All rights reserved.</div><div class="flex flex-column" style="gap:2rem;align-items:center"></div></div></div></div></div></div></div><script id="__NEXT_DATA__" type="application/json">{"props":{"pageProps":{"pageProps":{},"cache":{"main_menu":[{"name":"News","url":"/news","_type":"mainNavigation","navParent":null,"_rev":"0piGBXYU4xtr8AR7ctR4cP","_id":"f4f7de3f-a4d0-4634-be89-185d9be70195","sortOrder":1,"_updatedAt":"2021-01-27T13:54:55Z","subQuery":[],"is_active":true,"_createdAt":"2020-07-06T18:53:49Z"},{"_rev":"34u4WZPVf7HmRhpjBTBq4r","navParent":null,"subQuery":[{"children":[],"_updatedAt":"2020-07-06T19:01:07Z","_createdAt":"2020-07-06T19:00:59Z","_type":"mainNavigation","_id":"36796e9a-e503-4198-bdda-c424ab0d4503","name":"Podcasts","url":"/podcasts","is_active":true,"navParent":{"_ref":"baa2c771-db9b-43c0-9f60-8e639150998c","_type":"reference"},"_rev":"oLRA2Bq11mbiGcZggFcSuz"},{"_rev":"0IRgZfc6nyjKlJRwWBo1xT","url":"/shows","is_active":true,"navParent":{"_ref":"baa2c771-db9b-43c0-9f60-8e639150998c","_type":"reference"},"name":"Shows","_id":"9692eda5-dba0-40fe-925a-57d62bbcd0a0","_createdAt":"2022-10-14T21:19:42Z","_type":"mainNavigation","_updatedAt":"2022-11-04T13:38:06Z","children":[]},{"_rev":"eUasFf5wXNEF1LiRXhwPED","name":"State Of Sciences - Presentations","_updatedAt":"2022-12-12T18:53:42Z","_createdAt":"2022-12-12T18:53:42Z","url":"/state-of-sciences-presentations","children":[],"_id":"42a70687-43b0-4e53-8cdb-6886b3ac31aa","is_active":true,"navParent":{"_ref":"baa2c771-db9b-43c0-9f60-8e639150998c","_type":"reference"},"_type":"mainNavigation"},{"_type":"mainNavigation","_id":"969f97a4-2147-4b5f-b335-3ed41534bda9","is_active":true,"navParent":{"_ref":"baa2c771-db9b-43c0-9f60-8e639150998c","_type":"reference"},"_updatedAt":"2020-07-06T19:03:17Z","children":[],"_createdAt":"2020-07-06T19:03:17Z","_rev":"dsDuJ8RgDkZe5YdVQLrqNd","name":"Videos","url":"/videos"},{"url":"/webinars","_createdAt":"2020-07-09T19:53:44Z","name":"Webinars","_id":"b4bd470b-35e5-4217-88e9-23982c6ff10a","children":[],"_updatedAt":"2020-07-21T18:21:04Z","navParent":{"_ref":"baa2c771-db9b-43c0-9f60-8e639150998c","_type":"reference"},"_rev":"UP5DN8kgH0KgNaQFvnqFHP","is_active":true,"_type":"mainNavigation"}],"_updatedAt":"2020-07-06T19:02:20Z","url":"/videos","_type":"mainNavigation","is_active":true,"_createdAt":"2020-06-18T19:54:38Z","name":"Media","_id":"baa2c771-db9b-43c0-9f60-8e639150998c","sortOrder":2},{"sortOrder":3,"_rev":"351NvCjccsrS9yxaF3ChRd","name":"Multimedia Series","_type":"mainNavigation","_id":"a5c00038-fa1c-4aac-b884-0badd3bc0d72","_createdAt":"2023-01-27T19:48:18Z","_updatedAt":"2023-01-27T19:49:10Z","url":"/multimedia-series","navParent":null,"subQuery":[{"is_active":true,"_id":"0192b1c8-5e2a-4c01-8203-b34ad71ec999","url":"/cure-connections","_createdAt":"2023-03-30T17:08:54Z","_rev":"77mZ7PORfofI3dBGfLmStn","_updatedAt":"2023-03-30T17:08:54Z","_type":"mainNavigation","name":"CURE Connections®","navParent":{"_ref":"a5c00038-fa1c-4aac-b884-0badd3bc0d72","_type":"reference"},"children":[]},{"children":[],"_rev":"2MCZWtMCW1jfJl4yABL71d","_id":"d3921e99-220f-4dd1-a504-fbbc955e73e2","url":"/insights","_createdAt":"2023-01-27T19:51:16Z","_type":"mainNavigation","is_active":true,"navParent":{"_ref":"a5c00038-fa1c-4aac-b884-0badd3bc0d72","_type":"reference"},"name":"Insights","_updatedAt":"2023-01-27T19:51:16Z"},{"_id":"e1d3e324-eb42-4c13-9bb9-0e4b37e08704","_updatedAt":"2024-12-10T17:42:00Z","_type":"mainNavigation","url":"/medcast","is_active":true,"_createdAt":"2024-12-10T17:41:50Z","name":"Medcast","children":[],"navParent":{"_ref":"a5c00038-fa1c-4aac-b884-0badd3bc0d72","_type":"reference"},"_rev":"EnjHxnWG7nhsRUiWgCUdaG"},{"navParent":{"_ref":"a5c00038-fa1c-4aac-b884-0badd3bc0d72","_type":"reference"},"_type":"mainNavigation","is_active":true,"_createdAt":"2021-06-15T13:25:57Z","_rev":"hqLXDrrvqjVBQIYdPP7BUx","name":"Peer Exchange","_id":"2b268592-cb44-402a-8f19-6b3250eb54d2","url":"/peer-exchange","_updatedAt":"2023-01-27T19:50:40Z","children":[]},{"name":"Peers \u0026 Perspectives","_id":"4df21374-23a5-4900-96c8-f04040ef6497","is_active":true,"navParent":{"_ref":"a5c00038-fa1c-4aac-b884-0badd3bc0d72","_type":"reference"},"_updatedAt":"2024-03-06T14:18:48Z","children":[],"url":"/peers-and-perspective","_createdAt":"2023-01-27T19:51:46Z","_rev":"Y7jj4qevD6wsmmv1BNYxNi","_type":"mainNavigation"},{"is_active":true,"_id":"2b957949-0bdd-4e77-a582-8da4685e027b","_createdAt":"2023-07-19T16:07:41Z","name":"Special Report","url":"/special-report","children":[],"_rev":"XE9vnGgPXscpvWVDkqdNqL","_type":"mainNavigation","navParent":{"_ref":"a5c00038-fa1c-4aac-b884-0badd3bc0d72","_type":"reference"},"_updatedAt":"2025-02-14T19:19:48Z"}],"is_active":true},{"subQuery":[{"_rev":"mdPuorhvj3nUJt8rekN8C3","name":"Conference Coverage","_updatedAt":"2020-08-13T17:12:30Z","navParent":{"_ref":"408f125d-4a5e-4596-9e5c-b29b7d05a975","_type":"reference"},"_type":"mainNavigation","_createdAt":"2020-07-06T19:04:16Z","children":[],"url":"/latest-conference","is_active":true,"sortOrder":1,"_id":"9ce0e15c-561a-4dc5-b41b-20a481417d00"},{"url":"/conference","is_active":true,"_createdAt":"2020-07-06T19:04:01Z","sortOrder":2,"_rev":"Ta5zvuQiedEoSykjim90KZ","_type":"mainNavigation","name":"Conference Listing","navParent":{"_ref":"408f125d-4a5e-4596-9e5c-b29b7d05a975","_type":"reference"},"_id":"ccc6fa6c-d5e5-437e-ad0a-c88269c67d94","children":[],"_updatedAt":"2020-08-13T17:12:18Z"}],"_type":"mainNavigation","navParent":null,"sortOrder":4,"_updatedAt":"2023-01-27T19:49:21Z","_rev":"2MCZWtMCW1jfJl4yABJth7","name":"Conferences","_id":"408f125d-4a5e-4596-9e5c-b29b7d05a975","is_active":true,"_createdAt":"2020-06-18T19:53:45Z"},{"is_active":true,"sortOrder":5,"url":"/sap-partner","_createdAt":"2020-07-06T18:54:36Z","_type":"mainNavigation","_id":"bfeba0c4-342e-41ff-ae25-81a17f750a2a","subQuery":[],"_rev":"ycnEFlmTUqrxW08RfOBosE","_updatedAt":"2023-01-27T19:49:45Z","name":"Partners","navParent":null},{"_type":"mainNavigation","name":"CME/CE","_updatedAt":"2023-01-27T19:49:55Z","is_active":true,"navParent":null,"_createdAt":"2020-06-18T19:54:11Z","_id":"cdaaff11-e345-4ed4-b24a-f2c7ae881f16","url":"/continuing-education","subQuery":[],"sortOrder":6,"_rev":"2MCZWtMCW1jfJl4yABKCZb"},{"is_active":true,"_createdAt":"2020-07-06T19:02:35Z","_rev":"2MCZWtMCW1jfJl4yABKGAH","_updatedAt":"2023-01-27T19:50:05Z","_type":"mainNavigation","name":"Resources","sortOrder":7,"_id":"77e3cdec-ac7d-4b66-a62a-1b5fdd5b1412","navParent":null,"subQuery":[{"_type":"mainNavigation","name":"Digital Supplements","_createdAt":"2024-08-27T15:01:58Z","_updatedAt":"2024-08-27T15:02:25Z","is_active":true,"_id":"12aced21-d7f4-4af7-8245-34066e3b8450","navParent":{"_ref":"77e3cdec-ac7d-4b66-a62a-1b5fdd5b1412","_type":"reference"},"_rev":"qnuj1TG9WuzrClz6svf6Ej","children":[],"url":"/journals/supplements/digital-supplement"},{"navParent":{"_ref":"77e3cdec-ac7d-4b66-a62a-1b5fdd5b1412","_type":"reference"},"_createdAt":"2020-10-15T19:40:02Z","_rev":"uL49Jn9AVeINt8yYnxQdnu","_type":"mainNavigation","_id":"6021e1e5-f498-474a-9fc9-bb8be31c2d5f","url":"/interactive-tools","name":"Interactive Tools","children":[],"is_active":true,"_updatedAt":"2020-10-15T19:40:15Z"},{"navParent":{"_ref":"77e3cdec-ac7d-4b66-a62a-1b5fdd5b1412","_type":"reference"},"children":[],"name":"Live Events","_id":"3c7a968a-c6d1-48ff-9e2a-9fe6bcd54ae1","_updatedAt":"2020-07-17T22:53:00Z","is_active":true,"_createdAt":"2020-07-06T19:06:12Z","_type":"mainNavigation","_rev":"Rbpfm4lNh9K9vOrCWCwfUT","url":"/events"},{"url":"/press-release","is_active":true,"navParent":{"_ref":"77e3cdec-ac7d-4b66-a62a-1b5fdd5b1412","_type":"reference"},"_rev":"Nnr45qNrlMpP04fWDB4arl","_type":"mainNavigation","_id":"9acf789e-632d-44d3-a9e5-c533742d1982","_createdAt":"2020-07-06T19:02:14Z","_updatedAt":"2020-07-21T18:17:18Z","name":"Press Release","children":[]},{"is_active":true,"_createdAt":"2020-07-09T19:53:55Z","_type":"mainNavigation","_id":"aa16cae8-4e9b-494a-9b92-3cdc35dc4e56","_updatedAt":"2020-07-15T13:10:11Z","navParent":{"_ref":"77e3cdec-ac7d-4b66-a62a-1b5fdd5b1412","_type":"reference"},"name":"Publications","children":[],"_rev":"Rbpfm4lNh9K9vOrCWCZSDu","url":"/journals"},{"navParent":{"_ref":"77e3cdec-ac7d-4b66-a62a-1b5fdd5b1412","_type":"reference"},"_createdAt":"2020-07-08T19:32:22Z","_type":"mainNavigation","_id":"2d0688db-dbdf-45b2-885b-69faec225d5f","is_active":true,"url":"/sponsored","_rev":"oSc5kHnfSBKytb9HK9T9fJ","name":"Sponsored","_updatedAt":"2020-07-08T19:32:29Z","children":[]}]},{"_createdAt":"2023-08-30T20:12:43Z","_rev":"tPEnmlVIjqbfPxAFbRBMv1","name":"Advisory Board","_updatedAt":"2023-09-18T14:54:22Z","url":"/advisory-board","is_active":true,"sortOrder":8,"_type":"mainNavigation","_id":"6538071c-7020-461c-b63c-78d5cdefa3e7","navParent":null,"subQuery":[]},{"url":"https://one.hcplive.com/subscribe/","is_active":true,"name":"Subscribe","navParent":null,"blank":true,"needSegmentSupport":true,"sortOrder":9,"_updatedAt":"2024-03-08T15:28:59Z","subQuery":[],"_createdAt":"2020-07-22T13:50:09Z","_rev":"4t8uEPzSGXp25SPV3OLppK","_type":"mainNavigation","_id":"7307b9f9-2068-42ff-b90a-2f09cf867b1c"}],"sub_menu":[{"is_active":true,"name":"Spotlight","_id":"24bceebf-b407-47a7-bc61-7d4da2ac1957","navParent":null,"subQuery":[{"navParent":{"_ref":"24bceebf-b407-47a7-bc61-7d4da2ac1957","_type":"reference"},"_rev":"opKylK688YYdETOKCHNDh3","children":[],"is_active":true,"_createdAt":"2023-04-20T20:03:40Z","sortOrder":2,"_id":"fba846c7-cf39-43d4-92a4-44d07d316c30","_updatedAt":"2024-12-05T13:52:17Z","_type":"subNavigation","name":"FDA News","url":"clinical/fda-news"},{"navParent":{"_ref":"24bceebf-b407-47a7-bc61-7d4da2ac1957","_type":"reference"},"sortOrder":3,"name":"The Respiratory Report","_id":"db8615f2-22bb-4587-ad94-9ec36a18a135","is_active":true,"_updatedAt":"2024-12-05T13:52:37Z","_createdAt":"2024-09-17T14:42:43Z","_rev":"opKylK688YYdETOKCHNEu9","_type":"subNavigation","url":"/respiratory-report","children":[]},{"name":"DME \u0026 nAMD On-Demand Presentation","_updatedAt":"2024-12-05T14:10:50Z","navParent":{"_ref":"24bceebf-b407-47a7-bc61-7d4da2ac1957","_type":"reference"},"_type":"subNavigation","url":"https://www.hcplive.com/interactive-tools/dual-pathway-inhibition/chapter-1","children":[],"_createdAt":"2024-01-10T16:23:58Z","_rev":"5C7r9qKmADH0BJVlJ8jZzC","sortOrder":5,"_id":"66d7a80c-26a1-4a50-ab5b-23a6e2c80712","blank":true,"is_active":true}],"_createdAt":"2020-07-17T22:59:49Z","blank":false,"sortOrder":1,"_rev":"oLRA2Bq11mbiGcZggGrXKn","_type":"subNavigation","_updatedAt":"2020-07-17T22:59:49Z"},{"_id":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_updatedAt":"2020-07-17T22:59:56Z","_rev":"Rbpfm4lNh9K9vOrCWCwgjY","navParent":null,"subQuery":[{"_rev":"b03LVdkc2FoBJ0telqs7eU","_type":"subNavigation","_id":"71831116-7e8d-40ba-8ba1-1ddcd6d56e44","url":"/clinical/adhd","_createdAt":"2021-02-19T17:33:54Z","name":"ADHD","_updatedAt":"2021-03-02T14:23:29Z","is_active":true,"navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"children":[]},{"is_active":true,"name":"Allergy","_id":"c42e0522-d7ef-4d8b-a89a-58457c496039","_updatedAt":"2020-07-06T19:09:36Z","_rev":"34u4WZPVf7HmRhpjBTBukM","_type":"subNavigation","url":"/clinical/allergy","navParent":{"_type":"reference","_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede"},"_createdAt":"2020-06-18T20:02:05Z","children":[]},{"is_active":true,"_type":"subNavigation","navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"_createdAt":"2021-04-15T15:07:54Z","_id":"3c321073-e54f-4e5d-8edf-42b326d5ef15","_updatedAt":"2021-05-05T20:51:01Z","url":"/clinical/arterial-disease","name":"Arterial Disease","_rev":"j5M79pSfXw23SIOuVlRid1","children":[]},{"_updatedAt":"2020-07-06T19:09:10Z","children":[],"navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"name":"Cardiology","_id":"75d57cf8-8c62-441f-819f-dd5013a6f826","url":"/clinical/cardiology","is_active":true,"_type":"subNavigation","_createdAt":"2020-06-18T20:01:30Z","_rev":"4fn0XkMWk4LCkQOA03VnFT"},{"_updatedAt":"2021-05-26T15:31:14Z","url":"/clinical/dermatology","_type":"subNavigation","_createdAt":"2021-05-18T20:11:17Z","name":"Dermatology","_id":"3eb56fcc-d115-4331-a6f3-d1f79e9a985c","is_active":true,"navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"_rev":"0tja9556q5l5InhqnF0cKz","children":[]},{"_updatedAt":"2020-07-06T19:09:30Z","url":"/clinical/diabetes","is_active":true,"name":"Diabetes","_id":"75f75716-4781-4700-be9c-e1a55385b81a","_rev":"iKtw4N8j7SUoUxTg2zfHym","_type":"subNavigation","children":[],"navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"_createdAt":"2020-06-18T20:02:25Z"},{"_id":"8c71f03a-2abe-4d72-8811-44a9b884aaf7","_updatedAt":"2020-07-06T19:14:24Z","url":"/clinical/gastroenterology","navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"name":"Gastroenterology","_rev":"oLRA2Bq11mbiGcZggFcWbu","children":[{"_type":"subNavigation","_updatedAt":"2024-04-30T14:25:40Z","blank":false,"_createdAt":"2024-04-30T14:25:40Z","_rev":"awDwQ2PZ96JRXjsz8Oz1wW","name":"Alpha-1 antitrypsin deficiency","_id":"159650d1-eb5d-4f0c-9cee-6b24d049f654","url":"AATD","is_active":true,"navParent":{"_ref":"8c71f03a-2abe-4d72-8811-44a9b884aaf7","_type":"reference"}}],"is_active":true,"_createdAt":"2020-06-18T20:07:40Z","_type":"subNavigation"},{"_updatedAt":"2020-07-06T19:14:30Z","navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"name":"Geriatric Medicine","_rev":"34u4WZPVf7HmRhpjBTC04K","_id":"ba37c1bb-6e55-4b99-84a3-124c467065a5","children":[],"_type":"subNavigation","url":"/clinical/geriatrics","is_active":true,"_createdAt":"2020-06-18T20:08:01Z"},{"is_active":true,"_createdAt":"2023-10-04T15:50:22Z","_type":"subNavigation","_rev":"X03bJYt1K3pT4A1FkxdaIt","name":"Hematology","navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"_id":"e2d776fb-f588-4a01-95c2-2781feb0ef27","url":"hematology","_updatedAt":"2023-10-04T15:50:22Z","children":[{"is_active":true,"_rev":"EfCBW61lXUnn4wOifDStFd","_type":"subNavigation","name":"Anemia","_id":"93b40aa1-0e5a-47bd-90c7-80b0ba18be54","_updatedAt":"2023-10-05T14:15:56Z","url":"anemia","navParent":{"_ref":"e2d776fb-f588-4a01-95c2-2781feb0ef27","_type":"reference"},"_createdAt":"2023-10-04T15:50:31Z"}]},{"_createdAt":"2020-07-20T16:50:22Z","url":"https://www.contagionlive.com/","is_active":true,"navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"_rev":"kKEbnz9vfYiNAWM5yTspwK","_type":"subNavigation","name":"Infectious Disease","_id":"6d33bed2-cbf1-40ad-94d8-b956f8eeb336","_updatedAt":"2020-07-20T16:50:32Z","blank":true,"children":[]},{"url":"https://www.neurologylive.com/","name":"Neurology","_updatedAt":"2020-07-20T16:50:20Z","children":[{"navParent":{"_ref":"81d75dcb-c0c1-4131-9a16-77799bebb73e","_type":"reference"},"_rev":"gL5mbufLla0z6s1IdCTo7f","_type":"subNavigation","name":"Insomnia","is_active":true,"_createdAt":"2022-08-18T16:35:42Z","_id":"14caccf7-7748-45f2-a566-2b8760ce8a1d","_updatedAt":"2022-10-18T13:28:30Z","url":"clinical/insomnia"}],"navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"_rev":"kKEbnz9vfYiNAWM5yTspuS","_createdAt":"2020-07-20T16:49:59Z","_type":"subNavigation","_id":"81d75dcb-c0c1-4131-9a16-77799bebb73e","blank":true,"is_active":true},{"url":"/clinical/psychiatry","children":[],"_type":"subNavigation","name":"Psychiatry","_id":"3a5642e7-4978-4b13-a838-00a17effa962","_updatedAt":"2020-07-06T19:14:39Z","is_active":true,"_createdAt":"2020-06-18T20:11:57Z","_rev":"WaXZ1tzEWHjo6ee6dcDw7B","navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"}},{"_rev":"34u4WZPVf7HmRhpjBTC0Jt","url":"/clinical/pulmonology","navParent":{"_type":"reference","_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede"},"_updatedAt":"2020-07-06T19:14:43Z","children":[{"is_active":true,"navParent":{"_ref":"fc044d26-d3f0-4116-854e-eba5209f76a2","_type":"reference"},"_type":"subNavigation","_id":"4605bc90-0ad2-4b41-ad56-bc8dd39819ab","_updatedAt":"2024-04-30T14:25:21Z","_createdAt":"2024-04-30T14:25:21Z","_rev":"FVKqFrFv5OgrBrJpbuar92","name":"Alpha-1 antitrypsin deficiency","url":"AATD"}],"name":"Pulmonology","is_active":true,"_type":"subNavigation","_id":"fc044d26-d3f0-4116-854e-eba5209f76a2","_createdAt":"2020-06-18T20:12:25Z"},{"url":"/clinical/rheumatology","_createdAt":"2020-06-18T20:13:25Z","_rev":"WaXZ1tzEWHjo6ee6dcDwWj","children":[],"_id":"f1c63e0d-47b5-4506-8578-fa30739ece96","navParent":{"_ref":"d90b9f3c-c66b-4c95-80e0-0839f5aacede","_type":"reference"},"_type":"subNavigation","is_active":true,"_updatedAt":"2020-07-06T19:14:52Z","name":"Rheumatology"}],"name":"Clinical","is_active":true,"url":"/clinical","_createdAt":"2020-06-18T19:59:49Z","sortOrder":2,"_type":"subNavigation"},{"_rev":"s1AWpZqq7eamJttD9i11P7","_createdAt":"2020-07-22T13:54:11Z","name":"Video Series","navParent":null,"subQuery":[{"_createdAt":"2020-07-22T13:54:49Z","navParent":{"_ref":"b4b969bd-e797-4bfe-8f91-93d74d8ee7bf","_type":"reference"},"_type":"subNavigation","name":"Insights","_id":"2f21f5cc-bf6e-43d3-989d-dc9b44e44172","url":"/insights","children":[],"is_active":true,"_updatedAt":"2020-07-22T13:54:56Z","_rev":"UP5DN8kgH0KgNaQFvo058N"},{"_rev":"05fXEYAQ1sYANlWRaBEdsF","name":"News Network","navParent":{"_ref":"b4b969bd-e797-4bfe-8f91-93d74d8ee7bf","_type":"reference"},"_type":"subNavigation","_id":"abffe854-6bff-4cc9-b86d-719ed396e97b","_updatedAt":"2020-07-22T13:55:41Z","is_active":true,"children":[],"_createdAt":"2020-07-22T13:55:16Z","url":"/news-network"},{"navParent":{"_ref":"b4b969bd-e797-4bfe-8f91-93d74d8ee7bf","_type":"reference"},"_createdAt":"2020-07-22T13:55:48Z","_rev":"Rw1btq5gg3Z1Ecax7J3AaQ","_type":"subNavigation","_id":"e1f7b631-3986-4355-99ba-9d6f08b48f2c","_updatedAt":"2020-10-08T19:34:33Z","name":"Peers \u0026 Perspectives","is_active":true,"url":"/peers-perspectives","children":[]},{"is_active":true,"_id":"81dea83c-c25f-4746-beea-da8f72f6cba2","_updatedAt":"2020-07-22T13:58:39Z","navParent":{"_ref":"b4b969bd-e797-4bfe-8f91-93d74d8ee7bf","_type":"reference"},"_createdAt":"2020-07-22T13:58:26Z","name":"Post Conference Perspectives","_rev":"s1AWpZqq7eamJttD9i1447","_type":"subNavigation","url":"/post-conference-perspectives","children":[]}],"_updatedAt":"2020-07-22T13:54:11Z","is_active":true,"sortOrder":3,"_type":"subNavigation","_id":"b4b969bd-e797-4bfe-8f91-93d74d8ee7bf"}],"site_setting":{"description":"HCPLive is a comprehensive clinical news and information portal that provides physicians with up-to-date specialty and disease-specific resources designed to help them provide better care to patients. At HCPLive, you will find breaking news, video interviews with physician experts, in-depth conference coverage, finance and practice management updates, insight and analysis from physician contributors, and more.","siteURL":"www.hcplive.com","gaID":"UA-155582410-23,UA-11140057-1","_rev":"3GUDmcZdXMS7XYzeG12i72","name":"HCPLive - Clinical news for connected physicians","_createdAt":"2020-06-02T17:48:42Z","socialLinks":[{"_key":"89fa6fb1757e","title":"Facebook","url":"https://www.facebook.com/HCPLiveNews/","blank":true,"_type":"urlArray"},{"blank":true,"_type":"urlArray","_key":"521ace042737","title":"X","url":"https://twitter.com/HCPLiveNews "},{"title":"LinkedIn","url":"https://www.linkedin.com/company/hcplive","blank":true,"_type":"urlArray","_key":"53c27686f9be"},{"_type":"urlArray","_key":"a63ae0624a8e","title":"RSS","url":"/rss"}],"footerLinks":[{"url":"/about","_type":"urlArray","_key":"d1541b9c9c02","title":"About Us"},{"_type":"urlArray","_key":"da26b5e81063","title":"Advertise","url":"/advertise"},{"_type":"urlArray","_key":"440c8f7cfde1","title":"Editorial","url":"/editorial"},{"_key":"628466e4c98c","title":"Contact Us","url":"/contact-us","blank":false,"_type":"urlArray"},{"_type":"urlArray","_key":"023335c1bce0","title":"Do Not Sell My Information","url":"https://www.mjhlifesciences.com/ccpa?domain=www.hcplive.com","blank":true},{"url":"/privacy","blank":true,"_type":"urlArray","_key":"f3fcb3bac7f2","title":"Privacy"},{"blank":true,"_type":"urlArray","_key":"2ff530547271","title":"Terms \u0026 Conditions","url":"/terms"}],"_id":"siteSettings","enableSanity2":true,"creativeLayout":null,"masterHeadConfig":{"hasMain":true,"main":{"_type":"mainImage","alt":"HCP Live Network","asset":{"_type":"reference","_ref":"image-09f00492e5df5f66a0d97f316f6d3704619ba791-1054x146-png"}},"logos":[{"_type":"logo","main":{"asset":{"_ref":"image-b5b96ed84541c4a5461bb61d78bc0b3643cb5f5f-200x48-webp","_type":"reference"},"blank":true,"_type":"mainImage","alt":"ContagionLive","link":"https://www.contagionlive.com/"},"_key":"f1b690b5957e"},{"main":{"alt":"CGTLive","link":"https://www.cgtlive.com/","asset":{"_ref":"image-71753968937bf3534051f06947c588aff0995e5a-200x62-webp","_type":"reference"},"blank":true,"_type":"mainImage"},"_key":"e31123241345","_type":"logo"},{"_type":"logo","main":{"alt":"NeurologyLive","link":"https://www.neurologylive.com/","asset":{"_type":"reference","_ref":"image-c9975c8662fddaf0537185a01dee702b7c894a00-200x28-webp"},"blank":true,"_type":"mainImage"},"_key":"71c61481eb92"},{"_key":"df1c0c4d2f7c","_type":"logo","main":{"_type":"mainImage","alt":"HCPLive","link":"https://www.hcplive.com","asset":{"_ref":"image-419960ba9b4e1c4a3803065fae90f54317f2a00c-250x61-webp","_type":"reference"},"blank":false}},{"_key":"3c228ac88fb2","_type":"logo","main":{"blank":true,"_type":"mainImage","alt":"OncLive","link":"https://www.onclive.com","asset":{"_ref":"image-f4674f073f5d31865ac1ee601a40a7c471373ecf-200x41-webp","_type":"reference"}}},{"_type":"logo","main":{"alt":"Contemporary Pediatrics","link":"https://www.contemporarypediatrics.com/","asset":{"_ref":"image-00a790e70c1d5b7c705d5055510eae6eec1f5fc2-1132x313-png","_type":"reference"},"blank":true,"_type":"mainImage"},"_key":"bb6690e62181"},{"_type":"logo","main":{"alt":"Contemporary Obgyn","link":"https://www.contemporaryobgyn.net/","asset":{"_type":"reference","_ref":"image-ad767640ef35e891328e7b2876a57fb894156411-859x261-png"},"blank":true,"_type":"mainImage"},"_key":"53266cff90bb"}]},"_type":"siteSettings","creativeLayoutLatestNews":null,"_updatedAt":"2024-10-09T19:51:20Z","keywords":["medicine","medical","news","drugs","treatments","fda","health","healthcare","science","research","pipeline","pharmaceuticals","clinicians","insight","interviews","doctors","providers","allergy","pulmonology","dermatology","ophthalmology","cardiology","endocrinology","diabetes","psychiatry","internal medicine","primary care","rheumatology","gastroenterology","hematology","rare disease","infectious disease"]},"clinicalData":[{"sortOrder":null,"children":[{"_id":"topic_anaphylaxis","name":"Anaphylaxis","identifier":"anaphylaxis","sortOrder":1},{"_id":"fe512b06-3fc5-4f5d-b30a-df7ecb28a95e","name":"Food Allergy","identifier":"food-allergy","sortOrder":2},{"_id":"b5009398-92aa-4953-b86b-3bcc66e2e595","name":"Seasonal Allergy","identifier":"seasonal-allergy","sortOrder":3}],"_id":"topic_allergy","name":"Allergy","identifier":"allergy"},{"identifier":"biosimilars","sortOrder":null,"children":[],"_id":"7e030af3-2bfb-4393-b71a-6180d37f140b","name":"Biosimilars"},{"_id":"topic_cardiology","name":"Cardiology","identifier":"cardiology","sortOrder":null,"children":[{"_id":"419cb6e9-d06c-4ee6-953f-bbefb5b57947","name":"Arrhythmia","identifier":"arrhythmia","sortOrder":null},{"_id":"ffb1f3f4-40d5-47f1-8950-c29fae9c643f","name":"Atherosclerotic Cardiovascular Disease","identifier":"atherosclerotic-cardiovascular-disease","sortOrder":null},{"_id":"e7f67b9e-d4d2-43e7-a2b1-f6364715d332","name":"Cardiomyopathy","identifier":"cardiomyopathy","sortOrder":null},{"_id":"2f7bbeb0-5cf9-4915-b101-1154d1b62f87","name":"Dyslipidemia","identifier":"dyslipidemia","sortOrder":null},{"_id":"topic_heart-failure","name":"Heart Failure","identifier":"heart-failure","sortOrder":null},{"_id":"topic_hypertension","name":"Hypertension","identifier":"hypertension","sortOrder":null},{"_id":"topic_stroke","name":"Stroke","identifier":"stroke","sortOrder":null},{"_id":"edd2ed98-277d-47c8-9046-d6d32a1efdd7","name":"Structural Heart Disease","identifier":"structural-heart-disease","sortOrder":null},{"_id":"topic_vte","name":"Venous Thromboembolism","identifier":"vte","sortOrder":null}]},{"_id":"topic_dermatology","name":"Dermatology","identifier":"dermatology","sortOrder":null,"children":[{"_id":"topic_acne","name":"Acne","identifier":"acne","sortOrder":null},{"_id":"6693c91c-812d-4480-a9bc-4deb0db0d7aa","name":"Alopecia","identifier":"alopecia","sortOrder":null},{"_id":"topic_atopic-dermatitis","name":"Atopic Dermatitis","identifier":"atopic-dermatitis","sortOrder":null},{"_id":"topic_chronic-idiopathic-urticaria","name":"Chronic Idiopathic Urticaria","identifier":"chronic-idiopathic-urticaria","sortOrder":null},{"_id":"98710e1c-b4e6-480b-9ac0-e728051e6699","name":"Hidradenitis Suppurativa","identifier":"hidradenitis-suppurativa","sortOrder":null},{"_id":"topic_plaque-psoriasis","name":"Plaque Psoriasis","identifier":"plaque-psoriasis","sortOrder":null},{"_id":"topic_rosacea","name":"Rosacea","identifier":"rosacea","sortOrder":null},{"_id":"93d97c16-5d1e-4f47-80c7-1247e47b54ba","name":"Vitiligo","identifier":"vitiligo","sortOrder":null}]},{"_id":"topic_endocrinology","name":"Endocrinology","identifier":"endocrinology","sortOrder":null,"children":[{"_id":"a68a7602-e8ac-4872-9441-42e5de4a29b4","name":"Hormonal Disorders","identifier":"hormonal-disorders","sortOrder":null},{"_id":"52263dee-e084-4e01-99cd-415bd3a2d7e2","name":"Polycystic Ovary Syndrome","identifier":"polycystic-ovary-syndrome","sortOrder":null},{"_id":"d16f4a42-2aa6-4720-bce2-e6ac8847ae40","name":"Thyroid Disorders","identifier":"thyroid-disorders","sortOrder":null},{"_id":"3d8f15cd-3033-401b-b58f-f2879d00a68d","name":"Type 1 Diabetes","identifier":"type-1-diabetes","sortOrder":null},{"_id":"0b42f38c-7a65-4bb4-ac2d-86500db18ab8","name":"Type 2 Diabetes","identifier":"type-2-diabetes","sortOrder":null}]},{"name":"FDA News","identifier":"fda-news","sortOrder":null,"children":[],"_id":"ce30aa62-f935-4ba1-a191-6503014d4802"},{"children":[{"_id":"topic_coronavirus","name":"COVID-19","identifier":"coronavirus","sortOrder":null},{"_id":"topic_influenza","name":"Influenza","identifier":"influenza","sortOrder":null},{"_id":"topic_vaccination","name":"Vaccination","identifier":"vaccination","sortOrder":null}],"_id":"topic_family-medicine","name":"Family Medicine","identifier":"family-medicine","sortOrder":null},{"sortOrder":null,"children":[{"_id":"topic_c-difficile-resources","name":"C Difficile Infection","identifier":"c-difficile-resources","sortOrder":null},{"_id":"topic_gastroesophageal-reflux-disease","name":"Gastroesophageal Reflux Disease (GERD)","identifier":"gastroesophageal-reflux-disease","sortOrder":null},{"_id":"3dad5995-1067-4a04-8551-5c82f66d0265","name":"Inflammatory Bowel Disease","identifier":"ibd","sortOrder":null},{"_id":"topic_irritable-bowel-syndrome","name":"Irritable Bowel Syndrome","identifier":"irritable-bowel-syndrome","sortOrder":null},{"_id":"topic_peptic-ulcer","name":"Peptic Ulcer","identifier":"peptic-ulcer","sortOrder":null},{"_id":"topic_ulcerative-colitis","name":"Ulcerative Colitis","identifier":"ulcerative-colitis","sortOrder":null}],"_id":"topic_gastroenterology","name":"Gastroenterology","identifier":"gastroenterology"},{"_id":"topic_geriatrics","name":"Geriatrics","identifier":"geriatrics","sortOrder":null,"children":[{"_id":"topic_alzheimer-disease","name":"Dementia and Alzheimer Disease","identifier":"alzheimer-disease","sortOrder":null},{"_id":"topic_parkinsons-disease","name":"Parkinson Disease","identifier":"parkinsons-disease","sortOrder":null}]},{"_id":"4ef2c459-a5b5-460c-817e-84823ece5bdf","name":"Hematology","identifier":"hematology","sortOrder":null,"children":[{"_id":"d43b48c0-9ffc-4541-925c-d97faaec91b1","name":"Anemia","identifier":"anemia","sortOrder":null},{"_id":"86587783-54b0-4eb6-a489-6590ea144468","name":"Paroxysmal Nocturnal Hemoglobinuria","identifier":"paroxysmal-nocturnal-hemoglobinuria","sortOrder":null},{"_id":"d68aec14-ffef-437b-a71b-0b989c84ca2f","name":"Sickle Cell","identifier":"sickle-cell","sortOrder":null}]},{"name":"Hepatology","identifier":"hepatology","sortOrder":null,"children":[{"_id":"2d8a080a-b54d-4975-a55e-8b5fd75ce859","name":"Alpha-1 antitrypsin deficiency","identifier":"aatd","sortOrder":null},{"_id":"32a576ae-40ba-41c5-9128-7e158588ccda","name":"Cholangitis","identifier":"cholangitis","sortOrder":null},{"_id":"topic_hepatitis-c","name":"Hepatitis C","identifier":"hepatitis-c","sortOrder":null},{"_id":"82d0e148-23b4-480a-b0a5-f5bddfaaa00f","name":"MASH / MASLD","identifier":"mash-masld","sortOrder":null}],"_id":"44abda14-7b81-4a4f-ac34-a5e848aa62b2"},{"_id":"topic_hospital-medicine","name":"Hospital Medicine","identifier":"hospital-medicine","sortOrder":null,"children":[]},{"children":[{"_id":"topic_hiv-aids","name":"HIV/AIDS","identifier":"hiv-aids","sortOrder":null}],"_id":"topic_infectious-disease","name":"Infectious Disease","identifier":"infectious-disease","sortOrder":null},{"identifier":"internal-medicine","sortOrder":null,"children":[],"_id":"topic_internal-medicine","name":"Internal Medicine"},{"name":"Nephrology","identifier":"nephrology","sortOrder":null,"children":[{"_id":"8c48cb91-1dcf-4bbc-81e0-e494a5b51b4b","name":"Chronic Kidney Disease","identifier":"chronic-kidney-disease","sortOrder":null},{"_id":"23e43f09-f248-4adb-a02b-7704fb3aa4d3","name":"IgA Nephropathy","identifier":"berger-disease","sortOrder":null}],"_id":"topic_nephrology"},{"name":"Neurology","identifier":"neurology","sortOrder":null,"children":[{"_id":"topic_epilepsy","name":"Epilepsy","identifier":"epilepsy","sortOrder":null},{"_id":"topic_migraine","name":"Migraine","identifier":"migraine","sortOrder":null},{"_id":"topic_tardive-dyskinesia","name":"Tardive Dyskinesia","identifier":"tardive-dyskinesia","sortOrder":null},{"_id":"topic_tbi","name":"Traumatic Brain Injury","identifier":"tbi","sortOrder":null}],"_id":"topic_neurology"},{"_id":"219060ed-b55f-4010-8cd2-25f21defbffb","name":"Obesity Management","identifier":"obesity-management","sortOrder":null,"children":[]},{"_id":"topic_ophthalmology","name":"Ophthalmology","identifier":"ophthalmology","sortOrder":null,"children":[{"_id":"8d2ddf0a-2685-4e62-b599-c3fd9c9f1ad8","name":"Age-Related Macular Degeneration","identifier":"amd","sortOrder":null},{"_id":"topic_diabetic-macular-edema","name":"Diabetic Macular Edema","identifier":"diabetic-macular-edema","sortOrder":null},{"_id":"6b2e397a-6f65-477d-84f1-824a19559738","name":"Geographic Atrophy","identifier":"geographic-atrophy","sortOrder":null},{"_id":"topic_uveitis","name":"Uveitis","identifier":"uveitis","sortOrder":null}]},{"children":[{"_id":"topic_acute-pain","name":"Acute Pain","identifier":"acute-pain","sortOrder":null},{"_id":"topic_chronic-pain","name":"Chronic Pain","identifier":"chronic-pain","sortOrder":null},{"_id":"topic_multiple-sclerosis","name":"Multiple Sclerosis","identifier":"multiple-sclerosis","sortOrder":null},{"_id":"topic_neuropathic-pain","name":"Neuropathic Pain","identifier":"neuropathic-pain","sortOrder":null}],"_id":"topic_pain","name":"Pain","identifier":"pain","sortOrder":null},{"_id":"topic_pediatrics","name":"Pediatrics","identifier":"pediatrics","sortOrder":null,"children":[]},{"_id":"topic_psychiatry","name":"Psychiatry","identifier":"psychiatry","sortOrder":null,"children":[{"_id":"topic_adhd","name":"ADHD","identifier":"adhd","sortOrder":null},{"_id":"topic_addiction","name":"Addiction","identifier":"addiction","sortOrder":null},{"_id":"topic_bipolar-disorder","name":"Bipolar Disorder","identifier":"bipolar-disorder","sortOrder":null},{"_id":"topic_major-depressive-disorder","name":"Major Depressive Disorder","identifier":"major-depressive-disorder","sortOrder":null},{"_id":"d602c259-bbc8-45bb-ac7c-95fab4308ff1","name":"PTSD","identifier":"ptsd","sortOrder":null},{"_id":"topic_schizophrenia","name":"Schizophrenia","identifier":"schizophrenia","sortOrder":null}]},{"name":"Pulmonology","identifier":"pulmonology","sortOrder":null,"children":[{"_id":"topic_asthma","name":"Asthma","identifier":"asthma","sortOrder":null},{"_id":"topic_copd","name":"COPD","identifier":"copd","sortOrder":null},{"_id":"7eb7087e-3116-49aa-9954-6ab487a1b496","name":"Lung Cancer","identifier":"lung-cancer","sortOrder":null},{"_id":"b659bd77-5a33-40aa-9dd2-52188d680227","name":"Pulmonary Fibrosis","identifier":"pulmonary-fibrosis","sortOrder":null}],"_id":"topic_pulmonology"},{"_id":"topic_rare-diseases","name":"RDR Alert®","identifier":"rare-diseases","sortOrder":null,"children":[{"_id":"topic_amyloidosis","name":"Amyloidosis","identifier":"amyloidosis","sortOrder":null},{"_id":"topic_huntington-disease","name":"Huntington Disease","identifier":"huntington-disease","sortOrder":null},{"_id":"topic_lysosomal-storage-disorders","name":"Lysosomal Storage Disorders","identifier":"lysosomal-storage-disorders","sortOrder":null},{"_id":"ce50bece-5e53-4fbd-a6e9-945fd601d3ba","name":"Vasculitis","identifier":"vasculitis","sortOrder":null}]},{"_id":"topic_rheumatology","name":"Rheumatology","identifier":"rheumatology","sortOrder":null,"children":[{"_id":"topic_fibromyalgia","name":"Fibromyalgia","identifier":"fibromyalgia","sortOrder":null},{"_id":"topic_gout","name":"Gout","identifier":"gout","sortOrder":null},{"_id":"39ebe0b3-bfce-469d-bf9e-f6c9cef44ab7","name":"Lupus","identifier":"lupus","sortOrder":null},{"_id":"topic_osteoarthritis","name":"Osteoarthritis","identifier":"osteoarthritis","sortOrder":null},{"_id":"3d0ce4db-efb3-467c-9417-0324174be5a3","name":"Osteoporosis","identifier":"osteoporosis","sortOrder":null},{"_id":"topic_psoriatic-arthritis","name":"Psoriatic Arthritis","identifier":"psoriatic-arthritis","sortOrder":null},{"_id":"topic_rheumatoid-arthritis","name":"Rheumatoid Arthritis","identifier":"rheumatoid-arthritis","sortOrder":null},{"_id":"topic_spondyloarthritis","name":"Spondyloarthritis","identifier":"spondyloarthritis","sortOrder":null}]},{"_id":"topic_sleep","name":"Sleep","identifier":"sleep","sortOrder":null,"children":[{"_id":"topic_insomnia","name":"Insomnia","identifier":"insomnia","sortOrder":null},{"_id":"634d14f0-d228-4e86-b0eb-1e148aac0936","name":"Obstructive Sleep Apnea","identifier":"obstructive-sleep-apnea","sortOrder":null}]},{"identifier":"surgery","sortOrder":null,"children":[{"_id":"topic_plastic-surgery","name":"Plastic surgery","identifier":"plastic-surgery","sortOrder":null}],"_id":"topic_surgery","name":"Surgery"},{"_id":"topic_womens-health","name":"Women's Health","identifier":"womens-health","sortOrder":null,"children":[]}],"seo_data":[],"recent_news":[{"title":"Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis","summary":"These data suggest therapeutic modulation of IL-23 inhibitors for psoriasis in those who have shown stability may be a legitimate strategy to ensure efficacy and safety.","thumbnail":{"_type":"mainImage","alt":"Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis","asset":{"_ref":"image-ac119b2ba6368b92294f910860ad1801ffd6b01b-3232x3232-jpg","_type":"reference"}},"factCheckAuthorMapping":null,"contentCategory":{"_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory","name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91","_updatedAt":"2023-01-17T17:54:09Z"},"_id":"2d816086-8261-49de-8767-81254177e403","url":{"current":"dose-modulation-results-compared-in-risankizumab-guselkumab-for-psoriasis","_type":"slug"},"published":"2025-02-21T15:00:59.920Z","authorMapping":{"_id":"50390873-f609-4f23-b2f5-a613c054c1ac","biography":[{"_key":"7bbc0f222f10","markDefs":[{"_type":"link","href":"mailto:tsmith@mjhlifesciences.com","_key":"61fa5a3c02ca"}],"children":[{"_type":"span","marks":[],"text":"Tim Smith joined the MJH Life Sciences team as an assistant editor for HCPLive in August 2022. He graduated from UC Berkeley with a degree in political science, working in multimedia journalism as a staff writer prior to joining MJH. In his spare time, he enjoys reading, watching TV, listening to podcasts, and rock climbing. You can contact him at ","_key":"b4511b246e190"},{"_type":"span","marks":["61fa5a3c02ca"],"text":"tsmith@mjhlifesciences.com","_key":"b4511b246e191"},{"_type":"span","marks":[],"text":".","_key":"b4511b246e192"}],"_type":"block","style":"normal"}],"_updatedAt":"2022-08-24T19:55:19Z","firstName":"Tim","lastName":"Smith","_type":"author","url":{"current":"tim-smith","_type":"slug"},"displayName":"Tim Smith","_createdAt":"2022-08-24T19:55:19Z","_rev":"4cB9C6CTf03w1NIxZziTKh"}},{"summary":"A study analyzed hypersensitivity reactions to biologics for atopic diseases, highlighting reaction types, severity, and biologic discontinuation rates.","thumbnail":{"caption":"Valerie Jaroenpuntaruk, MD\nCredit: the Mayo Clinic","asset":{"_ref":"image-fc268f58f4ab164e0856cf8e8fdfb63765f22855-348x446-png","_type":"reference"},"_type":"mainImage","alt":"Valerie Jaroenpuntaruk, MD I Credit: the Mayo Clinic"},"published":"2025-02-21T13:00:00.000Z","factCheckAuthorMapping":null,"_id":"8b9ec1ba-2cf6-47ed-8927-34dc80d9240b","title":"Omalizumab Linked to Greatest Rate of Hypersensitivity Reactions in Atopic Diseases","url":{"current":"omalizumab-linked-to-greatest-rate-of-hypersensitivity-reactions-atopic-diseases","_type":"slug"},"authorMapping":{"biography":[{"children":[{"_key":"8bd338dea8b50","_type":"span","marks":[],"text":"Chelsie Derman is an associate editor for "},{"_key":"8bd338dea8b51","_type":"span","marks":["em"],"text":"HCPLive "},{"_key":"8bd338dea8b52","_type":"span","marks":[],"text":"who covers psychiatry, sleep medicine, geriatrics, migraine, and allergy. She joined MJH Life Sciences in September 2023 after graduating from The College of New Jersey with a bachelor’s degree in journalism and professional writing. In her free time, she enjoys creative writing and reading."}],"_type":"block","style":"normal","_key":"f0ce38fcc5dd","markDefs":[]},{"style":"normal","_key":"4e2e43e384c6","markDefs":[{"href":"cderman@mjhlifesciences.com","_key":"dc0c3e67806e","_type":"emailAddress"}],"children":[{"text":"She can be reached at ","_key":"3c09df6a4f1e0","_type":"span","marks":[]},{"_type":"span","marks":["dc0c3e67806e"],"text":"cderman@mjhlifesciences.com","_key":"ca6e10c8e1df"}],"_type":"block"}],"_updatedAt":"2025-01-17T16:04:39Z","firstName":"Chelsie","lastName":"Derman","authorType":"author","url":{"current":"chelsie-derman","_type":"slug"},"displayName":"Chelsie Derman","_createdAt":"2023-09-27T19:16:08Z","_rev":"PHYRau07g0l5Y4L0Wyi8OL","_type":"author","_id":"c91bc665-dc9f-464d-9ec0-b26014d056e3"},"contentCategory":{"_updatedAt":"2023-01-17T17:54:09Z","_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory","name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91"}},{"factCheckAuthorMapping":null,"_id":"d9823284-2f66-4323-a936-1993baee1a87","title":"New Biliary Atresia Guidance Released by American Academy of Pediatrics","summary":"The strategy detailed in the guidance aids the early identification of infants with biliary atresia and is intended for use between 2 and 4 weeks of life.","thumbnail":{"_type":"mainImage","alt":"Sanjiv Harpavat, MD, PhD | Credit: American Liver Foundation","asset":{"_ref":"image-0fd711f2bd49110973379ae60d69627fa166d7e4-750x750-png","_type":"reference"}},"contentCategory":{"_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory","name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91","_updatedAt":"2023-01-17T17:54:09Z"},"url":{"current":"new-biliary-atresia-guidance-released-american-academy-pediatrics","_type":"slug"},"published":"2025-02-21T11:00:00.000Z","authorMapping":{"firstName":"Abigail","lastName":"Brooks","displayName":"Abigail Brooks, MA","_createdAt":"2023-08-16T21:01:55Z","_type":"author","_id":"a4f8c360-5ae6-48cb-99c0-286a6b76f037","biography":[{"children":[{"_key":"1d7645ea6da80","_type":"span","marks":[],"text":"Abigail Brooks is an assistant editor for "},{"_type":"span","marks":["em"],"text":"HCPLive. ","_key":"1d7645ea6da81"},{"_type":"span","marks":[],"text":"She joined MJH Life Sciences in August 2023 shortly after graduating from Monmouth University where she earned her BA in Communication with a concentration in Public Relations/Journalism and later an MA in Interactive Digital Media. She enjoys traveling, running, and reading books. She can be reached at abrooks@mjhlifesciences.com.","_key":"1d7645ea6da82"}],"_type":"block","style":"normal","_key":"ad4ff818a6d3","markDefs":[]}],"_updatedAt":"2023-08-16T21:01:55Z","_rev":"sXRLufgca24g5WFAwOy51f","profileImage":{"_type":"mainImage","asset":{"_ref":"image-93bd0088a30dd94cde45491e60398457d8055321-1928x2700-jpg","_type":"reference"}},"url":{"current":"abigail-brooks","_type":"slug"}}},{"title":"Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis","summary":"In new data to be presented at AAAAI, the therapy was well-tolerated in people as young as 2 years old.","thumbnail":{"_type":"mainImage","alt":"Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati","caption":"Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis\n","asset":{"_ref":"image-f5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366-jpg","_type":"reference"}},"factCheckAuthorMapping":null,"contentCategory":{"_updatedAt":"2023-01-17T17:54:09Z","_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory","name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91"},"url":{"current":"tapinarof-consistent-efficacy-across-body-regions-ad","_type":"slug"},"published":"2025-02-21T00:00:46.772Z","authorMapping":{"lastName":"Johnson","_createdAt":"2020-12-10T20:09:41Z","_type":"author","displayName":"Victoria Johnson","_rev":"R5Nwo2wgBUbo1xFZSWuqlM","_id":"d4c32d40-a161-4f01-8151-702eff7a6e75","biography":[{"style":"normal","_key":"bf207805c002","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Victoria Johnson joined the MJH Life Sciences in 2020 and has written for NeurologyLive, CGTLive, and now HCPLive. You can reach her at vjohnson@mjhlifesciences.com","_key":"69caae9c35c7"}],"_type":"block"}],"_updatedAt":"2024-09-16T22:30:31Z","url":{"current":"victoria-johnson","_type":"slug"},"firstName":"Victoria"},"_id":"c9385425-36e7-46fa-835d-a7edf6ef58ff"}],"isLiveSite":true,"host":"www.hcplive.com","settings":{"title":"HCP Live","networkID":"4688","adUnit":"hcplive.com","liveDomain":"www.hcplive.com","logo":"/hcplive_logo_250_w.webp","white_logo":"/HCPlive_white.png","enableEdgeCache":true,"sMaxAge":300,"staleWhileRevalidate":359,"megaMenuTaxName":"clinical","sharingImageUrl":"https://s3.amazonaws.com/mjhlifesciences.com/sitelogos/HCPLive_1200x637.png","twitterHandle":"@MDMagazine","publicationMapping":"journals","publicationName":"HCPLive","clinicalDropDownLabel":"Related Topics","redesignDetail":true,"navigationOptions":{"variant":"2"},"gateEnabled":"modal"}},"targeting":{"content_placement":["home"],"document_url":["home"],"document_group":[],"rootDocumentGroup":[]},"data":{"topArticles":[{"authors":[{"displayName":"Tim Smith","url":"tim-smith"}],"title":"Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis","url":"dose-modulation-results-compared-in-risankizumab-guselkumab-for-psoriasis","thumbnail":{"alt":"Dose Modulation Results Compared in Risankizumab, Guselkumab for Psoriasis","asset":{"_ref":"image-ac119b2ba6368b92294f910860ad1801ffd6b01b-3232x3232-jpg","_type":"reference"},"_type":"mainImage"},"summary":"These data suggest therapeutic modulation of IL-23 inhibitors for psoriasis in those who have shown stability may be a legitimate strategy to ensure efficacy and safety.","published":"2025-02-21T15:00:59.920Z"},{"summary":"Panelists discuss how chronic obstructive pulmonary disease (COPD) management is evolving with personalized therapies, nonpharmacological care, and advanced treatments. Early diagnosis, adherence, and innovation offer hope for improved outcomes and quality of life.","published":"2025-02-21T13:05:00.000Z","authors":[{"displayName":"M. Bradley Drummond, MD, MHS","url":"m-bradley-drummond-md-mhs"},{"displayName":"MeiLan K. Han, MD, MS","url":"meilan-k-han-md-ms"},{"displayName":"Emily Wan, MD MPH","url":"emily-wan-md-mph"},{"displayName":"Ravi Kalhan, MD, MS","url":"ravi-kalhan-md-ms"}],"title":"Future Outlook in COPD","url":"future-outlook-in-copd","thumbnail":{"_type":"mainImage","asset":{"_ref":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","_type":"reference"}}},{"title":"Omalizumab Linked to Greatest Rate of Hypersensitivity Reactions in Atopic Diseases","url":"omalizumab-linked-to-greatest-rate-of-hypersensitivity-reactions-atopic-diseases","thumbnail":{"_type":"mainImage","alt":"Valerie Jaroenpuntaruk, MD I Credit: the Mayo Clinic","caption":"Valerie Jaroenpuntaruk, MD\nCredit: the Mayo Clinic","asset":{"_ref":"image-fc268f58f4ab164e0856cf8e8fdfb63765f22855-348x446-png","_type":"reference"}},"summary":"A study analyzed hypersensitivity reactions to biologics for atopic diseases, highlighting reaction types, severity, and biologic discontinuation rates.","published":"2025-02-21T13:00:00.000Z","authors":[{"displayName":"Chelsie Derman","url":"chelsie-derman"}]},{"title":"Vaccination and Pulmonary Rehabilitation in COPD","url":"vaccination-and-pulmonary-rehabilitation-in-copd","thumbnail":{"asset":{"_ref":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","_type":"reference"},"_type":"mainImage"},"summary":"Panelists discuss how key nonpharmacological interventions include vaccinations to prevent infections, pulmonary rehabilitation to improve function, and lung cancer screening for high-risk patients to enable early detection.","published":"2025-02-21T13:00:00.000Z","authors":[{"displayName":"M. Bradley Drummond, MD, MHS","url":"m-bradley-drummond-md-mhs"},{"displayName":"MeiLan K. Han, MD, MS","url":"meilan-k-han-md-ms"},{"displayName":"Emily Wan, MD MPH","url":"emily-wan-md-mph"},{"displayName":"Ravi Kalhan, MD, MS","url":"ravi-kalhan-md-ms"}]},{"title":"New Biliary Atresia Guidance Released by American Academy of Pediatrics","url":"new-biliary-atresia-guidance-released-american-academy-pediatrics","thumbnail":{"_type":"mainImage","alt":"Sanjiv Harpavat, MD, PhD | Credit: American Liver Foundation","asset":{"_ref":"image-0fd711f2bd49110973379ae60d69627fa166d7e4-750x750-png","_type":"reference"}},"summary":"The strategy detailed in the guidance aids the early identification of infants with biliary atresia and is intended for use between 2 and 4 weeks of life.","published":"2025-02-21T11:00:00.000Z","authors":[{"displayName":"Abigail Brooks, MA","url":"abigail-brooks"}]}],"newsArticles":[{"authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"}],"title":"Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis","url":"tapinarof-consistent-efficacy-across-body-regions-ad","thumbnail":{"_type":"mainImage","alt":"Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati","caption":"Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis\n","asset":{"_ref":"image-f5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366-jpg","_type":"reference"}},"summary":"In new data to be presented at AAAAI, the therapy was well-tolerated in people as young as 2 years old.","published":"2025-02-21T00:00:46.772Z"},{"published":"2025-02-20T23:00:46.596Z","authors":[{"displayName":"Connor Iapoce","url":"connor-iapoce"}],"title":"Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure","url":"rates-of-iron-deficiency-differ-by-clinical-definition-in-heart-failure","thumbnail":{"alt":"Rates of Iron Deficiency Differ by Clinical Definition in Heart Failure | Image Credit: Medical University of Innsbruck","asset":{"_ref":"image-8ed591956c6daeac8382b305046f918b710e3764-600x600-jpg","_type":"reference"},"_type":"mainImage"},"summary":"Iron deficiency was more common in acute versus chronic heart failure, with notable differences in detection by numerous recommended definitions.\n"},{"url":"pediatric-atopic-dermatitis-most-effectively-treated-upadacitinib-study-finds","thumbnail":{"asset":{"_type":"reference","_ref":"image-5dd1df201377c5abc2a448f2113e627ffa0aea8d-400x400-jpg"},"_type":"mainImage","alt":"Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds"},"summary":"These data were the result of a new network meta-analysis looking specifically at children with eczema, highlighting the hierarchy of effectiveness among systemic drugs.","published":"2025-02-20T21:00:42.115Z","authors":[{"displayName":"Tim Smith","url":"tim-smith"}],"title":"Pediatric Atopic Dermatitis Most Effectively Treated with Upadacitinib, Study Finds"},{"url":"expert-panel-develops-consensus-definition-clinical-tool-anaphylaxis-care","thumbnail":{"_type":"mainImage","alt":"Timothy E. Dribin, MD I Credit: Cincinnati Children’s Hospital Medical Center","caption":"Timothy E. Dribin, MD\nCredit: Cincinnati Children’s Hospital Medical Center","asset":{"_ref":"image-30d5991e9fd90975f8abee94b079a38f5da712c1-464x570-png","_type":"reference"}},"summary":"A 46-member expert panel created a consensus anaphylaxis definition, overview, and clinical tool to aid clinicians in recognition and management across settings.","published":"2025-02-20T20:00:00.000Z","authors":[{"displayName":"Chelsie Derman","url":"chelsie-derman"}],"title":"Expert Panel Develops Consensus Definition, Clinical Tool for Anaphylaxis Care"},{"title":"Clinical Quiz: Clinical Considerations in Food Allergy Prevention","url":"clinical-quiz-clinical-considerations-food-allergy-prevention","thumbnail":{"_type":"mainImage","alt":"Clinical Quiz: Dietary Diversity and Allergy Prevention","caption":"Clinical Quiz: Dietary Diversity and Allergy Prevention","asset":{"_ref":"image-08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940-png","_type":"reference"}},"summary":"In this quiz, we test your knowledge of recommendations to prevent food allergy development in infants.","published":"2025-02-20T19:22:30.748Z","authors":[{"displayName":"HCPLive Editorial Staff","url":"hcplive-editorial-staff"}]},{"title":"Add-on Remibrutinib Quickly Improves Urticaria Control in CSU","url":"add-on-remibrutinib-quickly-improves-urticaria-control-csu","thumbnail":{"caption":"Add-on Remibrutinib Quickly Improves Urticaria Control in CSU","asset":{"_ref":"image-3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450-tif","_type":"reference"},"_type":"mainImage","alt":"Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany"},"summary":"By week 52, remibrutinib and placebo-to-remibrutinib groups had similar levels of urticaria control.","published":"2025-02-20T18:00:21.129Z","authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"}]},{"authors":[{"displayName":"Abigail Brooks, MA","url":"abigail-brooks"}],"title":"Second Trimester Kidney Function Linked to Adverse Pregnancy Outcomes","url":"second-trimester-kidney-function-linked-adverse-pregnancy-outcomes","thumbnail":{"_type":"mainImage","alt":"Anika Lucas, MD | Credit: Duke University School of Medicine","asset":{"_type":"reference","_ref":"image-5f150b703174f7bda1b31493a017d41e551e30e1-872x872-png"}},"summary":"Low and high second-trimester eGFR values were linked to adverse pregnancy outcomes, including preeclampsia, preterm birth, low birth weight, and fetal loss.","published":"2025-02-20T17:00:12.570Z"},{"thumbnail":{"asset":{"_ref":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","_type":"reference"},"_type":"mainImage","alt":"Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center"},"summary":"Clark describes visual and anatomic improvements with aflibercept 8 mg in the PULSAR extension study, with most patients achieving extended dosing regimens.","published":"2025-02-20T16:15:12.251Z","authors":[{"displayName":"W. Lloyd Clark, MD","url":"w-lloyd-clark-md"},{"displayName":"Connor Iapoce","url":"connor-iapoce"}],"title":"Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD","url":"aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md"},{"authors":[{"displayName":"Chelsie Derman","url":"chelsie-derman"}],"title":"SPN-820 Fails Phase 2b Trial for Treatment-Resistant Depression","url":"spn-820-fails-phase-2b-trial-treatment-resistant-depression","thumbnail":{"_type":"mainImage","alt":"Credit: Adobe Stock/ Africa Studio","caption":"Credit: Adobe Stock/ Africa Studio","asset":{"_ref":"image-becc697436f8df85ec87549ea9ae200ba56682a3-898x596-png","_type":"reference"}},"summary":"A phase 2b trial showed that, unlike patients with MDD, patients with treatment-resistant depression do not receive significant benefits from SPN-820.","published":"2025-02-20T15:31:00.000Z"},{"published":"2025-02-20T15:02:57.000Z","authors":[{"displayName":"Tim Smith","url":"tim-smith"}],"title":"FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis ","url":"fda-clears-ind-application-zabalafin-hydrogel-treatment-of-atopic-dermatitis","thumbnail":{"_type":"mainImage","alt":"FDA Clears IND Application for Zabalafin Hydrogel Treatment of Atopic Dermatitis ","asset":{"_ref":"image-c19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400-jpg","_type":"reference"}},"summary":"Alpyn’s Investigational New Drug application’s clearance by the FDA for the new Zabalafin Hydrogel for atopic dermatitis follows positive phase 2a clinical findings."},{"title":"Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia","url":"gene-interaction-increases-patients-risk-of-frontal-fibrosing-alopecia","thumbnail":{"_type":"mainImage","alt":"Gene Interaction Increases Patients’ Risk of Frontal Fibrosing Alopecia","asset":{"_ref":"image-e6192a743ebd63874848e078b799f6de2e899ae0-300x300-jpg","_type":"reference"}},"summary":"This genome-wide meta-analysis demonstrated that changes in 2 parts of the genome both work to influence patients’ risk of frontal fibrosing alopecia (FFA).","published":"2025-02-20T15:00:10.741Z","authors":[{"displayName":"Tim Smith","url":"tim-smith"}]},{"authors":[{"displayName":"Giselle Mosnaim, MD, MS ","url":"giselle-mosnaim-md-ms"},{"displayName":"Shyam Joshi, MD ","url":"shyam-joshi-md"},{"displayName":"Mark Lebwohl, MD","url":"mark-lebwohl-md"},{"displayName":"Jason Hawkes, MD, MS","url":"jason-hawkes-md-ms"}],"title":"How BTK Inhibitors Differ From Current CSU Treatment Approaches","url":"how-btk-inhibitors-differ-from-current-csu-treatment-approaches","thumbnail":{"_type":"mainImage","asset":{"_ref":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","_type":"reference"}},"summary":"Panelists discuss how Bruton tyrosine kinase (BTK) inhibitors offer a novel upstream approach, in contrast to current treatments that work downstream by either blocking released mediators (antihistamines), neutralizing circulating IgE (omalizumab), or broadly suppressing immune responses (immunosuppressants).","published":"2025-02-20T13:05:00.000Z"},{"title":"BTK Inhibition as a Strategy for CSU Treatment","url":"btk-inhibition-as-a-strategy-for-csu-treatment","thumbnail":{"_type":"mainImage","asset":{"_ref":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","_type":"reference"}},"summary":"Panelists discuss how Bruton tyrosine kinase (BTK) inhibition could effectively treat both autoallergic and autoimmune chronic spontaneous urticaria (CSU).","published":"2025-02-20T13:00:00.000Z","authors":[{"displayName":"Giselle Mosnaim, MD, MS ","url":"giselle-mosnaim-md-ms"},{"displayName":"Shyam Joshi, MD ","url":"shyam-joshi-md"},{"displayName":"Mark Lebwohl, MD","url":"mark-lebwohl-md"},{"displayName":"Jason Hawkes, MD, MS","url":"jason-hawkes-md-ms"}]},{"url":"multidisciplinary-care-model-improves-liver-metabolic-outcomes-mash","thumbnail":{"alt":"Jonathan Stine, MD, MSc | Credit: Penn State Health","asset":{"_ref":"image-e9b7501faffbfa350e7062d5dbb132f814e6cf14-1014x1014-png","_type":"reference"},"_type":"mainImage"},"summary":"The multidisciplinary care model included 7 co-located specialists who aided patient education, lifestyle intervention, and drug therapy strategies for MASH.","published":"2025-02-20T11:00:00.000Z","authors":[{"displayName":"Abigail Brooks, MA","url":"abigail-brooks"}],"title":"Multidisciplinary Care Model Improves Liver, Metabolic Outcomes in MASH"},{"published":"2025-02-20T00:06:54.912Z","authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"},{"displayName":"James Chalmers, MBChB, PhD","url":"james-chalmers-mbchb-phd"}],"title":"Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD","url":"investigating-brensocatib-first-treatment-bronchiectasis-chalmers","thumbnail":{"_type":"mainImage","alt":"Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD","caption":"Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD","asset":{"_ref":"image-1e39f2bffa24ec93339878a0450fab82714d105f-320x320-webp","_type":"reference"}},"summary":"Chalmers discussed how brensocatib’s potential approval may transform the currently empty treatment landscape for bronchiectasis."},{"summary":null,"published":"2025-02-19T23:00:36.096Z","authors":[{"displayName":"W. Lloyd Clark, MD","url":"w-lloyd-clark-md"},{"displayName":"Connor Iapoce","url":"connor-iapoce"}],"title":"Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD","url":"aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md","thumbnail":{"alt":"Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD | Image Credit: Palmetto Retinal Center","asset":{"_ref":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","_type":"reference"},"_type":"mainImage"}},{"authors":[{"displayName":"Tim Smith","url":"tim-smith"},{"displayName":"Shuai (Steve) Xu, MD, MSc,","url":"shuai-steve-xu-md-msc-"},{"displayName":"Kailas Vodrahalli","url":"kailas-vodrahalli"},{"displayName":"Harald Kittler, MD","url":"harald-kittler-md"}],"title":"AI in Dermatology: Emerging Insights and Diverging Perspectives","url":"ai-in-dermatology-emerging-insights-and-diverging-perspectives","thumbnail":{"_type":"mainImage","alt":"AI in Dermatology: Emerging Insights and Diverging Perspectives","asset":{"_ref":"image-27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400-jpg","_type":"reference"}},"summary":"In this feature, 3 experts highlight their own research on new technological advances and their views on the benefits and drawbacks of artificial intelligence in dermatology.","published":"2025-02-19T21:00:13.952Z"},{"title":"Clinical Quiz: Dietary Diversity and Allergy Prevention","url":"clinical-quiz-dietary-diversity-allergy-prevention","thumbnail":{"caption":"Clinical Quiz: Dietary Diversity and Allergy Prevention","asset":{"_ref":"image-08ba5f6ce1cca28af49699af1b3020f44a78f06a-936x940-png","_type":"reference"},"_type":"mainImage","alt":"Clinical Quiz: Dietary Diversity and Allergy Prevention"},"summary":"In this quiz, we test your knowledge of recommendations for introducing dietary diversity to infants.","published":"2025-02-19T19:00:00.000Z","authors":[{"displayName":"HCPLive Editorial Staff","url":"hcplive-editorial-staff"}]},{"thumbnail":{"_type":"mainImage","alt":"Sozinibercept Topline Results Expected in Q2 After COAST Trial Completion| Image Credit: Opthea","asset":{"_ref":"image-6b8f4b8ef650d8b864c1e76076eefdfee0eae4e4-800x800-jpg","_type":"reference"}},"summary":"The first of two Phase 3 pivotal trials investigating sozinibercept, COAST completed its final week 52 visit in patients with wet AMD.","published":"2025-02-19T16:00:17.637Z","authors":[{"displayName":"Connor Iapoce","url":"connor-iapoce"}],"title":"Sozinibercept Topline Results Expected in Q2 After COAST Trial Completion","url":"sozinibercept-topline-results-expected-in-q2-after-coast-trial-completion"},{"title":"Amneal Launches Mesalamine for Ulcerative Colitis, Receives Lenalidomide FDA Approval","url":"amneal-launches-mesalamine-ulcerative-colitis-receives-lenalidomide-fda-approval","thumbnail":{"_type":"mainImage","alt":"FDA black and white logo | Credit: US Food and Drug Administration","asset":{"_ref":"image-8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400-webp","_type":"reference"}},"summary":"Amneal Pharmaceuticals launched mesalamine 800 mg delayed-release tablets for UC and received FDA approval for various lenalidomide doses for blood cancers.","published":"2025-02-19T15:04:48.569Z","authors":[{"displayName":"Abigail Brooks, MA","url":"abigail-brooks"}]},{"title":"Major Risk Factors Identified Which May Limit Oral JAK Inhibitor Use in HS","url":"major-risk-factors-identified-which-may-limit-oral-jak-inhibitor-use-in-hs","thumbnail":{"_type":"mainImage","alt":"Major Risk Factors Identified Which May Limit Oral JAK Inhibitor Use in HS","asset":{"_type":"reference","_ref":"image-1b7255c8e81631df3248c7cd37895578f2a880a3-400x400-jpg"}},"summary":"This analysis highlights the major risk factors resulting in limited use of oral JAKi for patients with hidradenitis suppurativa, including smoking, obesity, hypertension, and age.","published":"2025-02-19T15:00:00.000Z","authors":[{"displayName":"Tim Smith","url":"tim-smith"}]},{"authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"}],"title":"FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia","url":"fda-rejects-pitolisant-nda-idiopathic-hypersomnia","thumbnail":{"_type":"mainImage","alt":"FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia","caption":"FDA Rejects Pitolisant NDA for Idiopathic Hypersomnia","asset":{"_ref":"image-c19f9b84461ae7978f62fb84d1c8791e249bcfc7-400x400-jpg","_type":"reference"}},"summary":"Pitolisant was evaluated for the supplemental indication in the phase 3 INTUNE study, which did not meet its primary outcome of reducing excessive daytime sleepiness.","published":"2025-02-19T14:57:02.846Z"},{"url":"nebokitug-cm-101-gets-fda-runway-psc-approval","thumbnail":{"_type":"mainImage","alt":"FDA black and white logo | Credit: US Food and Drug Administration","asset":{"_ref":"image-8c9fc7db85bab8d7795d7e7f3fe25112d090c457-400x400-webp","_type":"reference"}},"summary":"Chemomab completed an end-of-phase 2 meeting with the FDA and has aligned on the design of a phase 3 registration study for nebokitug (CM-101) in PSC.","published":"2025-02-19T14:24:48.833Z","authors":[{"displayName":"Abigail Brooks, MA","url":"abigail-brooks"}],"title":"Nebokitug (CM-101) Gets FDA Runway for PSC Approval"},{"thumbnail":{"_type":"mainImage","alt":"Thomas Vanwolleghem, MD, PhD | Credit: Thomas Vanwolleghem on LinkedIn","asset":{"_type":"reference","_ref":"image-89bd7dfa62e7c4005786e6a9eb56da78185e5b97-751x748-png"}},"summary":"HDV RNA-positive patients were more often diagnosed with advanced liver fibrosis and had a 4.7-fold greater risk of severe liver-related outcomes.","published":"2025-02-19T11:00:00.000Z","authors":[{"displayName":"Abigail Brooks, MA","url":"abigail-brooks"}],"title":"HDV RNA Positivity Linked to Greater Risk of Severe Liver-Related Outcomes","url":"hdv-rna-positivity-linked-greater-risk-severe-liver-related-outcomes"},{"title":"Ruxolitinib Shows Clinical Benefit in Children, Adults With Atopic Dermatitis","url":"ruxolitinib-clinical-benefit-children-adults-atopic-dermatitis","thumbnail":{"_type":"mainImage","alt":"Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health \u0026 Science University","caption":"Ruxolitinib Shows Clinical Benefit in Children, Adults With Atopic Dermatitis","asset":{"_ref":"image-1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300-jpg","_type":"reference"}},"summary":"Data from 3 pooled phase 3 studies in children, adolescents, and adults will be presented at the AAAI/WAO Joint Congress.","published":"2025-02-19T00:00:40.183Z","authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"}]}],"latestVideos":[{"_id":"616052c8-a4d3-4bec-95a2-27cf94bba3c3","title":"Future Outlook in COPD","url":"future-outlook-in-copd","thumbnail":{"asset":{"sha1hash":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_updatedAt":"2024-12-23T16:47:36Z","extension":"png","_rev":"d85e4RNWNOToFCQ813A8oh","size":1252826,"assetId":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","_id":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","originalFilename":"Marketing Image (68).png","metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnJtbxS$R5WARP~qofNGV@of-;e-ofoMWV","_type":"sanity.imageMetadata","palette":{"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.52,"background":"#58110b"},"lightMuted":{"population":6.39,"background":"#cbb7a7","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"background":"#bc1934","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.01},"dominant":{"background":"#58110b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.52},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.96,"background":"#32375a"},"muted":{"population":6.05,"background":"#876b71","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"title":"#000","population":1.98,"background":"#d1deea","_type":"sanity.imagePaletteSwatch","foreground":"#000"}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"uploadId":"oUch4WEsQdZlRPM2Xzm6fyEM7fUwxdy0","path":"images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_type":"sanity.imageAsset","mimeType":"image/png","_createdAt":"2024-12-23T16:47:36Z"}},"link":"/view/undefined"},{"_id":"afc9b2bf-10dc-45fe-b73d-4025eda9af78","title":"Vaccination and Pulmonary Rehabilitation in COPD","url":"vaccination-and-pulmonary-rehabilitation-in-copd","thumbnail":{"asset":{"sha1hash":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_updatedAt":"2024-12-23T16:47:36Z","extension":"png","_rev":"d85e4RNWNOToFCQ813A8oh","size":1252826,"assetId":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","_id":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","originalFilename":"Marketing Image (68).png","metadata":{"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnJtbxS$R5WARP~qofNGV@of-;e-ofoMWV","_type":"sanity.imageMetadata","palette":{"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000","population":1.98,"background":"#d1deea"},"darkVibrant":{"title":"#fff","population":6.52,"background":"#58110b","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"foreground":"#000","title":"#fff","population":6.39,"background":"#cbb7a7","_type":"sanity.imagePaletteSwatch"},"vibrant":{"title":"#fff","population":0.01,"background":"#bc1934","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"background":"#58110b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.52},"_type":"sanity.imagePalette","darkMuted":{"background":"#32375a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.96},"muted":{"title":"#fff","population":6.05,"background":"#876b71","_type":"sanity.imagePaletteSwatch","foreground":"#fff"}},"hasAlpha":true},"uploadId":"oUch4WEsQdZlRPM2Xzm6fyEM7fUwxdy0","path":"images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_type":"sanity.imageAsset","mimeType":"image/png","_createdAt":"2024-12-23T16:47:36Z"}},"link":"/view/undefined"},{"_id":"81ad9042-7688-45a8-8e40-d82cf285e725","title":"Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD","url":"aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md","thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg","extension":"jpg","size":15600,"assetId":"6d87f07338586a48041ba67e900189789aa40d8a","uploadId":"TTF2WdHDaiIZTf2ZMQ6iguHLdrxvluOA","_type":"sanity.imageAsset","path":"images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg","_id":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","_updatedAt":"2023-11-05T17:22:08Z","originalFilename":"W. Lloyd Clark, MD.jpeg","mimeType":"image/jpeg","sha1hash":"6d87f07338586a48041ba67e900189789aa40d8a","_createdAt":"2023-11-05T17:22:08Z","metadata":{"isOpaque":true,"blurHash":"eIG8yO?H5kNG^j~VRPpIbIIA9FRjRQazoeENofrWs:x^XSay%2ayM{","_type":"sanity.imageMetadata","palette":{"vibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0,"background":"#3a74c4"},"dominant":{"foreground":"#000","title":"#fff","population":7.65,"background":"#c2a499","_type":"sanity.imagePaletteSwatch"},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.59,"background":"#604234"},"muted":{"foreground":"#fff","title":"#fff","population":1.79,"background":"#a3715e","_type":"sanity.imagePaletteSwatch"},"lightVibrant":{"background":"#e0a491","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":4.83},"darkVibrant":{"title":"#fff","population":0.02,"background":"#0b1625","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"title":"#fff","population":7.65,"background":"#c2a499","_type":"sanity.imagePaletteSwatch","foreground":"#000"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"height":300,"_type":"sanity.imageDimensions","width":300,"aspectRatio":1}},"_rev":"BpNdyQCG1dl0w7WYXlIgvj"}},"link":"/view/undefined"},{"_id":"907d18f4-bf69-4989-938b-010de74beb3b","title":"How BTK Inhibitors Differ From Current CSU Treatment Approaches","url":"how-btk-inhibitors-differ-from-current-csu-treatment-approaches","thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","size":2172584,"_rev":"XE9vnGgPXscpvWVDknVLRB","path":"images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","_id":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","_updatedAt":"2025-02-13T17:04:35Z","originalFilename":"TL.00_00_24_13.Still002.png","extension":"png","metadata":{"_type":"sanity.imageMetadata","palette":{"darkVibrant":{"background":"#261404","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.05},"lightMuted":{"title":"#fff","population":0.09,"background":"#d6b0b5","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34},"dominant":{"population":3.34,"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":2.91,"background":"#373d4d","_type":"sanity.imagePaletteSwatch"},"muted":{"title":"#fff","population":2.73,"background":"#aa8081","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightVibrant":{"title":"#000","population":2.99,"background":"#edd4d3","_type":"sanity.imagePaletteSwatch","foreground":"#000"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":true,"blurHash":"MpIE@SRjS%kCxu~qayX9ofs:jZazoza{RP"},"_type":"sanity.imageAsset","mimeType":"image/png","sha1hash":"895ac0390c516bb6677b19ecd0040c5f858f0796","uploadId":"oSnXepOqjz9K6IGvwhhGjyoWZ8FoxhUd","assetId":"895ac0390c516bb6677b19ecd0040c5f858f0796","_createdAt":"2025-02-13T17:04:35Z"}},"link":"/view/undefined"},{"_id":"43dd5f84-badf-4269-9748-440b9d021bd8","title":"BTK Inhibition as a Strategy for CSU Treatment","url":"btk-inhibition-as-a-strategy-for-csu-treatment","thumbnail":{"asset":{"extension":"png","metadata":{"palette":{"darkVibrant":{"background":"#261404","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.05},"lightMuted":{"foreground":"#000","title":"#fff","population":0.09,"background":"#d6b0b5","_type":"sanity.imagePaletteSwatch"},"vibrant":{"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34},"dominant":{"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":2.91,"background":"#373d4d","_type":"sanity.imagePaletteSwatch"},"muted":{"background":"#aa8081","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.73},"lightVibrant":{"title":"#000","population":2.99,"background":"#edd4d3","_type":"sanity.imagePaletteSwatch","foreground":"#000"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":true,"blurHash":"MpIE@SRjS%kCxu~qayX9ofs:jZazoza{RP","_type":"sanity.imageMetadata"},"_type":"sanity.imageAsset","mimeType":"image/png","sha1hash":"895ac0390c516bb6677b19ecd0040c5f858f0796","uploadId":"oSnXepOqjz9K6IGvwhhGjyoWZ8FoxhUd","assetId":"895ac0390c516bb6677b19ecd0040c5f858f0796","_createdAt":"2025-02-13T17:04:35Z","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","size":2172584,"_rev":"XE9vnGgPXscpvWVDknVLRB","path":"images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","_id":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","_updatedAt":"2025-02-13T17:04:35Z","originalFilename":"TL.00_00_24_13.Still002.png"}},"link":"/view/undefined"},{"_id":"04775208-b774-4a8e-af2b-7681676b6e44","title":"Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD","url":"investigating-brensocatib-first-treatment-bronchiectasis-chalmers","thumbnail":{"asset":{"extension":"webp","_rev":"cID2mV6fSdv64jOtmNsNRV","mimeType":"image/webp","size":9822,"assetId":"1e39f2bffa24ec93339878a0450fab82714d105f","originalFilename":"chalmers.webp","_id":"image-1e39f2bffa24ec93339878a0450fab82714d105f-320x320-webp","_createdAt":"2025-02-20T00:11:57Z","sha1hash":"1e39f2bffa24ec93339878a0450fab82714d105f","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp","path":"images/0vv8moc6/hcplive/1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp","metadata":{"_type":"sanity.imageMetadata","palette":{"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":12.09,"background":"#614718"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":9.01,"background":"#725a34","_type":"sanity.imagePaletteSwatch"},"muted":{"background":"#a38372","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":10.83},"lightVibrant":{"background":"#e4b6ae","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.05},"darkVibrant":{"background":"#614718","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":12.09},"lightMuted":{"background":"#c4a293","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":10.27},"vibrant":{"background":"#bc6474","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"width":320,"aspectRatio":1,"height":320,"_type":"sanity.imageDimensions"},"isOpaque":true,"blurHash":"e5GHuI,m00%#^N00tT-;8_Nf00-O}[tT-nVCE6-;r;EQ0jR$~A-;9@"},"uploadId":"wXbNK6mZhvncEquaHtNIRqxhS6u5tT7E","_type":"sanity.imageAsset","_updatedAt":"2025-02-20T00:11:57Z"}},"link":"/view/undefined"},{"_id":"d4083e60-03e8-4e5d-8404-9f97c8c5d98b","title":"Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD","url":"aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md","thumbnail":{"asset":{"extension":"jpg","size":15600,"assetId":"6d87f07338586a48041ba67e900189789aa40d8a","uploadId":"TTF2WdHDaiIZTf2ZMQ6iguHLdrxvluOA","_type":"sanity.imageAsset","path":"images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg","_id":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","_updatedAt":"2023-11-05T17:22:08Z","originalFilename":"W. Lloyd Clark, MD.jpeg","mimeType":"image/jpeg","sha1hash":"6d87f07338586a48041ba67e900189789aa40d8a","_createdAt":"2023-11-05T17:22:08Z","metadata":{"lqip":"data:image/jpeg;base64,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","dimensions":{"height":300,"_type":"sanity.imageDimensions","width":300,"aspectRatio":1},"isOpaque":true,"blurHash":"eIG8yO?H5kNG^j~VRPpIbIIA9FRjRQazoeENofrWs:x^XSay%2ayM{","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"background":"#604234","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.59},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.79,"background":"#a3715e"},"lightVibrant":{"background":"#e0a491","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":4.83},"darkVibrant":{"title":"#fff","population":0.02,"background":"#0b1625","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"title":"#fff","population":7.65,"background":"#c2a499","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"foreground":"#fff","title":"#fff","population":0,"background":"#3a74c4","_type":"sanity.imagePaletteSwatch"},"dominant":{"population":7.65,"background":"#c2a499","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"}},"hasAlpha":false},"_rev":"BpNdyQCG1dl0w7WYXlIgvj","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg"}},"link":"/view/undefined"},{"_id":"674b3cf3-e594-4131-9da6-2fe424ed0e8a","title":"AI in Dermatology: Emerging Insights and Diverging Perspectives","url":"ai-in-dermatology-emerging-insights-and-diverging-perspectives","thumbnail":{"asset":{"_id":"image-27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400-jpg","originalFilename":"pexels-ivan-samkov-4989171.jpg","uploadId":"sYZms91fzvjjN6B1LX6iGV7RgtDdqaHy","_rev":"ivaRGNxFBepXyTXsuKWZnp","_type":"sanity.imageAsset","mimeType":"image/jpeg","sha1hash":"27b7211cf03e0b68aaeb16548693de243d74bfd7","path":"images/0vv8moc6/hcplive/27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg","_updatedAt":"2025-02-19T19:32:36Z","extension":"jpg","metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":400,"aspectRatio":1,"height":400},"isOpaque":true,"blurHash":"ekL4g0%M%MWBt7?wR*azWAR*-:RiWBR*WBD*RjxaofofxaozWCt7WV","_type":"sanity.imageMetadata","palette":{"muted":{"background":"#aa9676","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":9.51},"lightVibrant":{"foreground":"#000","title":"#000","population":0,"background":"#e4cca4","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"population":8.72,"background":"#4a321c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"population":7.77,"background":"#c5bdb0","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"background":"#d4a880","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0},"dominant":{"foreground":"#000","title":"#fff","population":9.51,"background":"#aa9676","_type":"sanity.imagePaletteSwatch"},"_type":"sanity.imagePalette","darkMuted":{"population":2.24,"background":"#57452d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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"},"size":51651,"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg","assetId":"27b7211cf03e0b68aaeb16548693de243d74bfd7","_createdAt":"2025-02-19T19:32:36Z"}},"link":"/view/undefined"},{"_id":"0d93cfd0-4dbd-4134-ae47-9525a0ee8193","title":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","url":"skin-of-color-savvy-news-update-addressing-disparities-black-history-month-mentorship-opportunities","thumbnail":{"asset":{"metadata":{"isOpaque":true,"blurHash":"VES~q;tRx]xabvxuWqofoLbb?wofM{kDe-?vsmRjWXjE","_type":"sanity.imageMetadata","palette":{"lightMuted":{"title":"#fff","population":0.02,"background":"#d7c4ac","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"foreground":"#fff","title":"#fff","population":0.03,"background":"#ce5a22","_type":"sanity.imagePaletteSwatch"},"dominant":{"background":"#3f322a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.47},"_type":"sanity.imagePalette","darkMuted":{"background":"#3f322a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.47},"muted":{"background":"#a57055","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.33},"lightVibrant":{"population":0,"background":"#fca474","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"darkVibrant":{"background":"#713112","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,/9j/2wBDAAYEBQYFBAYGBQYHBwYIChAKCgkJChQODwwQFxQYGBcUFhYaHSUfGhsjHBYWICwgIyYnKSopGR8tMC0oMCUoKSj/2wBDAQcHBwoIChMKChMoGhYaKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCj/wAARCAANABQDASIAAhEBAxEB/8QAGQAAAgMBAAAAAAAAAAAAAAAAAAECAwQI/8QAHxAAAQUAAQUAAAAAAAAAAAAAAQACAxEhBBNBUVJx/8QAFAEBAAAAAAAAAAAAAAAAAAAAAf/EABYRAQEBAAAAAAAAAAAAAAAAAAABEf/aAAwDAQACEQMRAD8A6dl5cjbLIrAsb5VbObM5uwgH6t5aDeDUumz1CMp2FE8vjDiKJ7IUwKFBCQ//2Q==","dimensions":{"_type":"sanity.imageDimensions","width":4176,"aspectRatio":1.5806207418622256,"height":2642}},"_rev":"d85e4RNWNOToFCQ826spTr","mimeType":"image/jpeg","path":"images/0vv8moc6/hcplive/5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg","size":467261,"originalFilename":"HCPLive SOCS Logo update.jpg","extension":"jpg","uploadId":"UkWU0x248b0tvJWbTkE2uO8lY7FzTZnJ","_type":"sanity.imageAsset","sha1hash":"5b991868daab2ad6287b75ffd968ecd8e44181a7","assetId":"5b991868daab2ad6287b75ffd968ecd8e44181a7","_createdAt":"2025-01-06T12:59:58Z","_id":"image-5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642-jpg","_updatedAt":"2025-01-06T12:59:58Z","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg"}},"link":"/view/undefined"},{"_id":"b9bc870d-494a-4cf6-8975-6622ac811c54","title":"Safety Data With Biologics in Atopic Dermatitis","url":"safety-data-with-biologics-in-atopic-dermatitis","thumbnail":{"asset":{"extension":"png","sha1hash":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","size":1228069,"originalFilename":"Marketing Image - 2024-12-24T091913.556.png","_rev":"5K24o7vC94LP4crFJHTRn6","_updatedAt":"2024-12-24T14:24:15Z","uploadId":"tRZtfAPN89t4PeZm1FfsoaO1PgPSPAwP","_type":"sanity.imageAsset","mimeType":"image/png","path":"images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","_createdAt":"2024-12-24T14:24:15Z","_id":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","metadata":{"dimensions":{"width":1920,"aspectRatio":1.7777777777777777,"height":1080,"_type":"sanity.imageDimensions"},"isOpaque":false,"blurHash":"MnINs}X9RPWURk~qo0WBaeWC-qRjkCjZoe","_type":"sanity.imageMetadata","palette":{"vibrant":{"foreground":"#fff","title":"#fff","population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch"},"dominant":{"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.73},"_type":"sanity.imagePalette","darkMuted":{"title":"#fff","population":4.7,"background":"#3b2925","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0,"background":"#b4946c"},"lightVibrant":{"population":0.26,"background":"#ecb9a8","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"darkVibrant":{"population":0.02,"background":"#810418","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"population":0.03,"background":"#bacddc","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000"}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","assetId":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f"}},"link":"/view/undefined"},{"_id":"36f6c629-cbb6-4e16-bbe8-f227bdce95e4","title":"Use of Combination Therapy in Atopic Dermatitis","url":"use-of-combination-therapy-in-atopic-dermatitis","thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","assetId":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","extension":"png","sha1hash":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","size":1228069,"originalFilename":"Marketing Image - 2024-12-24T091913.556.png","_rev":"5K24o7vC94LP4crFJHTRn6","_updatedAt":"2024-12-24T14:24:15Z","uploadId":"tRZtfAPN89t4PeZm1FfsoaO1PgPSPAwP","_type":"sanity.imageAsset","mimeType":"image/png","path":"images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","_createdAt":"2024-12-24T14:24:15Z","_id":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","metadata":{"isOpaque":false,"blurHash":"MnINs}X9RPWURk~qo0WBaeWC-qRjkCjZoe","_type":"sanity.imageMetadata","palette":{"dominant":{"population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"population":4.7,"background":"#3b2925","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0,"background":"#b4946c"},"lightVibrant":{"title":"#fff","population":0.26,"background":"#ecb9a8","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"foreground":"#fff","title":"#fff","population":0.02,"background":"#810418","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"population":0.03,"background":"#bacddc","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000"},"vibrant":{"population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"width":1920,"aspectRatio":1.7777777777777777,"height":1080,"_type":"sanity.imageDimensions"}}}},"link":"/view/undefined"},{"_id":"dae00c38-f11a-486f-af2f-7ccb26302816","title":"The Medical Sisterhood: Men, Medicine, and Their Female Mentors","url":"the-medical-sisterhood-white-coats-wingmen-how-men-can-uplift-women-in-medicine","thumbnail":{"asset":{"_type":"sanity.imageAsset","_createdAt":"2025-02-18T17:53:32Z","_id":"image-48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200-png","_updatedAt":"2025-02-18T17:53:32Z","extension":"png","uploadId":"1SqDYpNOdaaNtxtVbCdeiJG5cmTuPvtj","sha1hash":"48a42c96bb84d8067d9522bd8af433c69b4dea94","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png","size":690849,"metadata":{"blurHash":"eMPOlS.RMe#=~X-;t%V[VuR%^S-;s,NZE0TqMyV@oy%MXPS^nOoftk","_type":"sanity.imageMetadata","palette":{"lightVibrant":{"population":0.3,"background":"#f1dd8c","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000"},"darkVibrant":{"background":"#8d2c3d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.1},"lightMuted":{"title":"#fff","population":0.3,"background":"#d4afc7","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"title":"#fff","population":0.01,"background":"#ec3794","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"background":"#452a2d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.74},"_type":"sanity.imagePalette","darkMuted":{"population":7.74,"background":"#452a2d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"population":3.76,"background":"#926b48","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1200,"aspectRatio":1,"height":1200},"isOpaque":true},"_rev":"Fd1jDX9jbPHQLM4ybhpFpE","mimeType":"image/png","assetId":"48a42c96bb84d8067d9522bd8af433c69b4dea94","originalFilename":"Podcast Square Thumbs (4).png","path":"images/0vv8moc6/hcplive/48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png"}},"link":"/view/undefined"},{"_id":"6655cff5-8957-4f9f-aff5-ba87ac5cba94","title":"A Primary Care Perspective on Diagnosing Atopic Dermatitis","url":"a-primary-care-perspective-on-diagnosing-atopic-dermatitis","thumbnail":{"asset":{"_rev":"5MymcCPmeJiqJMv8mbGqeF","mimeType":"image/png","extension":"png","uploadId":"vUDttLD8iks5qHEhpWfveoGmVDwEqJSn","size":1603635,"_updatedAt":"2025-02-14T15:20:16Z","originalFilename":"marketing image (5).png","metadata":{"isOpaque":true,"blurHash":"MlI}I%OEIUW-RP~qaxRPWBWX.8nikCjFj]","_type":"sanity.imageMetadata","palette":{"lightVibrant":{"title":"#fff","population":0,"background":"#fcbc7c","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":4.6,"background":"#74181a"},"lightMuted":{"population":0.6,"background":"#a8c4d2","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"title":"#fff","population":0.02,"background":"#ba6c34","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"population":6.71,"background":"#9f8678","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"title":"#fff","population":0.02,"background":"#345448","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.71,"background":"#9f8678"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080}},"_type":"sanity.imageAsset","sha1hash":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","path":"images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","_createdAt":"2025-02-14T15:20:16Z","_id":"image-2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080-png","assetId":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937"}},"link":"/view/undefined"},{"_id":"c33f9111-e780-4a88-924c-c0304e02fea5","title":"Considerations for Switching Systemic Agents in Atopic Dermatitis","url":"considerations-for-switching-systemic-agents-in-atopic-dermatitis","thumbnail":{"asset":{"extension":"png","_updatedAt":"2025-01-03T19:58:20Z","originalFilename":"Marketing Image - 2025-01-03T145812.788.png","mimeType":"image/png","sha1hash":"0878bfa7cd08e89066336e7089ede6c234290179","path":"images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","size":1418782,"assetId":"0878bfa7cd08e89066336e7089ede6c234290179","_id":"image-0878bfa7cd08e89066336e7089ede6c234290179-1920x1080-png","metadata":{"dimensions":{"height":1080,"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777},"isOpaque":true,"blurHash":"MmH_MmR*i_j=M|~qjERjaya}.8a#W;aeoJ","_type":"sanity.imageMetadata","palette":{"lightMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.88,"background":"#b7867b"},"vibrant":{"background":"#9d3030","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":5.32},"dominant":{"background":"#59120f","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.08},"_type":"sanity.imagePalette","darkMuted":{"population":6.51,"background":"#54413a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"background":"#8f7f75","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.55},"lightVibrant":{"title":"#fff","population":0.71,"background":"#d7bda3","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"background":"#59120f","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.08}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"uploadId":"670OHsVYqwO0HYIucVdjSWngIxEQY6S3","_rev":"5K24o7vC94LP4crFKji536","_type":"sanity.imageAsset","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","_createdAt":"2025-01-03T19:58:20Z"}},"link":"/view/undefined"},{"_id":"b318d2c0-e681-4bfd-94fd-04a990cc42d0","title":"Expectations for Efficacy and Duration of Response With Systemic Atopic Dermatitis Treatments","url":"expectations-for-efficacy-and-duration-of-response-with-systemic-atopic-dermatitis-treatments","thumbnail":{"asset":{"mimeType":"image/png","sha1hash":"0878bfa7cd08e89066336e7089ede6c234290179","path":"images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","size":1418782,"assetId":"0878bfa7cd08e89066336e7089ede6c234290179","_id":"image-0878bfa7cd08e89066336e7089ede6c234290179-1920x1080-png","metadata":{"blurHash":"MmH_MmR*i_j=M|~qjERjaya}.8a#W;aeoJ","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"title":"#fff","population":6.51,"background":"#54413a","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.55,"background":"#8f7f75"},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.71,"background":"#d7bda3"},"darkVibrant":{"background":"#59120f","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.08},"lightMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.88,"background":"#b7867b"},"vibrant":{"foreground":"#fff","title":"#fff","population":5.32,"background":"#9d3030","_type":"sanity.imagePaletteSwatch"},"dominant":{"background":"#59120f","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.08}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAALCAYAAAB/Ca1DAAAACXBIWXMAAAPoAAAD6AG1e1JrAAAAFHRFWHRDcmVhdG9yAFByZW1pZXJlIFByb2l7TwQAAAMKSURBVHicVcnLT9MHAMDx31+xGXHLBogQxktSkUcLfVEQin3RFx1CebWlSIWWPmhLWbVFWpFC49jGpplxYXNZolPUFZCYyEFmFhez0y5eFg+LoZ1xx++yLVmyw+f0EX59vMfP39/hl0ePePniBa8PDnhTKPAmn//Pn4XCv/L/9/e9PsjzR77Aq1cH/Pbyd4Q72VVurWa4+8Vn7H53kyf377L/4B77D+7zdHeX/Z2HPN68x97mJj/mcjzb3ub5zhbPH27xbCfHT9s5nua2eHJ7k70b3yDMtstIDttY8rr+sTLjJuMbJxOYZj2zzOWFRWbH3cQm3KzMRbm+mODmUpyN5RjXFmb5JB5mLZ7kc2+YLzVGhJHyYmYMHUTHLCScfaTdNqJDeiKOM6QTCfw+P+N9VgKjQ1wIBVm/lOSrbIxPL06yNGPn4pSby/NprgaT3GhVIQyVvYenR0bCZWMjco6NqIeoXYfXbiEeCnN2eAyP1UJ8YpzU3BzX17J8vZ5mKTxCalTH2qSbTDRDxnOBa83tCH3FRxhVNpJ22fjhfJBbUS9hm4ax3tOcc0wwaLAy3NWDv3+A874A66tZrq6miDhMzOukXBkcIGz3M6waJFFxAsFw5G3MTbXE+vXcDk/zbcCD19CFXtGGSWfGoFJzRt7OVK+ZkOssCx8lSMUiuA0d+KTHuaTV4lQPoq5X43u/GkFbdIiu+lqGdBqu+Lx87A9g12iQNzahkCqRN7bQ2yTG0X0ap62f0LSXOY8Ts1SE/fhRwkoZxtZTqGpa8ZZUIfQUFSGrP4lGayMYSBKOLGMyjdDWKEYsEnGiugqVqAGjXIG+s4PJASvzTjN90jos9eVMKFoxtMn4sFlMorIaoefwYVR1DZg0/UxPJfD6lzEbnShETcg+qEBcXoaquoZukQh5XQ026UliZgUzXS04JQ24lTJc3Z1ET8nJ1lQh6A+9hbGiklGJAp/WxpTFgU2pR11Zi+FoKZaSUqwlZWiKS5G/+w76YyWEWupZlEuYFzcTlEiIdraTkotZqTjGXx6hB/JWym2SAAAAAElFTkSuQmCC","dimensions":{"height":1080,"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777},"isOpaque":true},"uploadId":"670OHsVYqwO0HYIucVdjSWngIxEQY6S3","_rev":"5K24o7vC94LP4crFKji536","_type":"sanity.imageAsset","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","_createdAt":"2025-01-03T19:58:20Z","extension":"png","_updatedAt":"2025-01-03T19:58:20Z","originalFilename":"Marketing Image - 2025-01-03T145812.788.png"}},"link":"/view/undefined"},{"_id":"f418306a-7db8-4a0e-909c-46a6bbd5690b","title":"Considerations for Diagnosis of Atopic Dermatitis in Adults","url":"considerations-for-diagnosis-of-atopic-dermatitis-in-adults","thumbnail":{"asset":{"assetId":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937","_rev":"5MymcCPmeJiqJMv8mbGqeF","mimeType":"image/png","extension":"png","uploadId":"vUDttLD8iks5qHEhpWfveoGmVDwEqJSn","size":1603635,"_updatedAt":"2025-02-14T15:20:16Z","originalFilename":"marketing image (5).png","metadata":{"isOpaque":true,"blurHash":"MlI}I%OEIUW-RP~qaxRPWBWX.8nikCjFj]","_type":"sanity.imageMetadata","palette":{"darkMuted":{"population":0.02,"background":"#345448","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"title":"#fff","population":6.71,"background":"#9f8678","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightVibrant":{"foreground":"#000","title":"#fff","population":0,"background":"#fcbc7c","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":4.6,"background":"#74181a"},"lightMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.6,"background":"#a8c4d2"},"vibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.02,"background":"#ba6c34"},"dominant":{"title":"#fff","population":6.71,"background":"#9f8678","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"_type":"sanity.imagePalette"},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080}},"_type":"sanity.imageAsset","sha1hash":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","path":"images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","_createdAt":"2025-02-14T15:20:16Z","_id":"image-2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080-png"}},"link":"/view/undefined"}],"videoSeriesData":[{"published":"2025-02-21T13:05:00.000Z","summary":"Panelists discuss how chronic obstructive pulmonary disease (COPD) management is evolving with personalized therapies, nonpharmacological care, and advanced treatments. Early diagnosis, adherence, and innovation offer hope for improved outcomes and quality of life.","ExcludeFromPubMedXML":false,"documentGroupMapping":[{"_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526","_type":"reference","_key":"ea0d9592c2e2"}],"contentCategory":{"name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory"},"seoTag":["COPD management","COPD","COPD prevention","COPD diagnosis","Chronic obstructive pulmonary disease"],"showSocialShare":true,"authorMapping":[{"_type":"author","_id":"17f58209-caa1-4311-83aa-76c2b68b0431","_updatedAt":"2024-12-23T16:45:03Z","displayName":"M. Bradley Drummond, MD, MHS","_createdAt":"2024-12-23T16:44:59Z","_rev":"nWtwX1K15VoXyHNzqntSRn","url":{"current":"m-bradley-drummond-md-mhs","_type":"slug"},"authorType":"expert"},{"url":{"current":"meilan-k-han-md-ms","_type":"slug"},"displayName":"MeiLan K. Han, MD, MS","_rev":"Z3pPQn8kInHPss3kunpVqi","_type":"author","_id":"29deaac6-e4ad-4cd2-ab0c-e49222b7e377","_updatedAt":"2024-12-23T16:45:24Z","authorType":"expert","_createdAt":"2024-12-23T16:45:19Z"},{"authorType":"expert","displayName":"Emily Wan, MD MPH","_rev":"kSEheplhqbTVfPV93CoxTR","_type":"author","url":{"current":"emily-wan-md-mph","_type":"slug"},"_createdAt":"2024-12-23T16:45:34Z","_id":"463b5158-ebf7-436c-8d43-5994e7ec000d","_updatedAt":"2024-12-23T16:45:38Z"},{"_createdAt":"2024-12-23T16:45:52Z","_id":"2b9dc7d6-c081-417c-9f32-eab0706ea7f6","url":{"current":"ravi-kalhan-md-ms","_type":"slug"},"authorType":"expert","displayName":"Ravi Kalhan, MD, MS","_rev":"niOyneYhvNl2SVQWMxfDTV","_type":"author","_updatedAt":"2024-12-23T16:45:56Z"}],"documentGroup":{"_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526","_type":"reference"},"url":{"current":"future-outlook-in-copd","_type":"slug"},"_id":"616052c8-a4d3-4bec-95a2-27cf94bba3c3","thumbnail":{"asset":{"mimeType":"image/png","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","assetId":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","uploadId":"oUch4WEsQdZlRPM2Xzm6fyEM7fUwxdy0","_rev":"d85e4RNWNOToFCQ813A8oh","_type":"sanity.imageAsset","sha1hash":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","_createdAt":"2024-12-23T16:47:36Z","_id":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","extension":"png","metadata":{"palette":{"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.52,"background":"#58110b"},"_type":"sanity.imagePalette","darkMuted":{"title":"#fff","population":0.96,"background":"#32375a","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.05,"background":"#876b71"},"lightVibrant":{"title":"#000","population":1.98,"background":"#d1deea","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"background":"#58110b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.52},"lightMuted":{"title":"#fff","population":6.39,"background":"#cbb7a7","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"foreground":"#fff","title":"#fff","population":0.01,"background":"#bc1934","_type":"sanity.imagePaletteSwatch"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnJtbxS$R5WARP~qofNGV@of-;e-ofoMWV","_type":"sanity.imageMetadata"},"size":1252826,"originalFilename":"Marketing Image (68).png","path":"images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_updatedAt":"2024-12-23T16:47:36Z"}},"is_visible":true,"_rev":"PHYRau07g0l5Y4L0XCYO33","_createdAt":"2025-01-20T14:47:28Z","_type":"article","title":"Future Outlook in COPD","articleType":"Opinion","_updatedAt":"2025-01-20T14:48:42Z","taxonomyMapping":[{"identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z"},{"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8","summary":[{"_type":"block","style":"normal","_key":"8de93ead7686","markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}]}]},{"_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0"},{"identifier":"copd","_id":"topic_copd","_updatedAt":"2021-03-12T23:09:23Z","summary":[{"markDefs":[],"children":[{"_key":"a93ed19c195c","_type":"span","marks":[],"text":"On the "},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"a717dd6a302d"},{"marks":[],"text":"COPD condition center page, resources on the topics of medical news and expert insight into chronic obstructive pulmonary disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on COPD research, treatment, and drug development.","_key":"fa4d38c12dca","_type":"span"}],"_type":"block","style":"normal","_key":"002ff14623bd"}],"parent":{"_ref":"topic_pulmonology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"duatTUEfMZ8Ma3bwePOSKv","_type":"taxonomy","name":"COPD"}],"body":[{"source":"brightcove","_key":"5f8621b98ebd","videoObject":{"videoTitle":"Future Outlook in COPD","thumbnail":{"_type":"image","asset":{"_ref":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","_type":"reference"}},"videoDuration":"HCP4m54s","videoDescription":"Panelists discuss how chronic obstructive pulmonary disease (COPD) management is evolving with personalized therapies, nonpharmacological care, and advanced treatments. Early diagnosis, adherence, and innovation offer hope for improved outcomes and quality of life.","_type":"videoDetails"},"_type":"video","videoID":"6367091667112","disableAutoPlayVideo":false},{"style":"normal","_key":"416ae49ca90d","markDefs":[],"children":[{"_type":"span","marks":["em","strong"],"text":"Video content above is prompted by the following:","_key":"f4edcaa9d1a30"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Please share your closing thoughts about COPD management and outlook for the future.","_key":"543d5f06babb"}],"level":1,"_type":"block","style":"normal","_key":"bd9d00754913","listItem":"bullet"}],"link":"/view/future-outlook-in-copd"},{"_type":"article","taxonomyMapping":[{"identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z"},{"summary":[{"_type":"block","style":"normal","_key":"8de93ead7686","markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}]}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8"},{"isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical"},{"identifier":"copd","_id":"topic_copd","_updatedAt":"2021-03-12T23:09:23Z","summary":[{"children":[{"_key":"a93ed19c195c","_type":"span","marks":[],"text":"On the "},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"a717dd6a302d"},{"marks":[],"text":"COPD condition center page, resources on the topics of medical news and expert insight into chronic obstructive pulmonary disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on COPD research, treatment, and drug development.","_key":"fa4d38c12dca","_type":"span"}],"_type":"block","style":"normal","_key":"002ff14623bd","markDefs":[]}],"parent":{"_ref":"topic_pulmonology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"duatTUEfMZ8Ma3bwePOSKv","_type":"taxonomy","name":"COPD"}],"link":"/view/vaccination-and-pulmonary-rehabilitation-in-copd","url":{"current":"vaccination-and-pulmonary-rehabilitation-in-copd","_type":"slug"},"summary":"Panelists discuss how key nonpharmacological interventions include vaccinations to prevent infections, pulmonary rehabilitation to improve function, and lung cancer screening for high-risk patients to enable early detection.","ExcludeFromPubMedXML":false,"articleType":"Opinion","body":[{"videoID":"6367091295112","disableAutoPlayVideo":false,"source":"brightcove","_key":"5f8621b98ebd","videoObject":{"videoDescription":"Panelists discuss how key nonpharmacological interventions include vaccinations to prevent infections, pulmonary rehabilitation to improve function, and lung cancer screening for high-risk patients to enable early detection.","_type":"videoDetails","videoTitle":"Vaccination and Pulmonary Rehabilitation in COPD","thumbnail":{"_type":"image","asset":{"_ref":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","_type":"reference"}},"videoDuration":"HCP6m25s"},"_type":"video"},{"children":[{"_type":"span","marks":["em","strong"],"text":"Video content above is prompted by the following:","_key":"f4edcaa9d1a30"}],"_type":"block","style":"normal","_key":"416ae49ca90d","markDefs":[]},{"listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"What nonpharmacological interventions should one consider for their patients, including vaccination, pulmonary rehabilitation, and lung cancer screening?","_key":"360d73d9cc92"}],"level":1,"_type":"block","style":"normal","_key":"b740ad755f3d"}],"_createdAt":"2025-01-20T14:40:25Z","_id":"afc9b2bf-10dc-45fe-b73d-4025eda9af78","published":"2025-02-21T13:00:00.000Z","title":"Vaccination and Pulmonary Rehabilitation in COPD","contentCategory":{"_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z"},"_updatedAt":"2025-01-20T14:41:26Z","thumbnail":{"asset":{"mimeType":"image/png","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","assetId":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","uploadId":"oUch4WEsQdZlRPM2Xzm6fyEM7fUwxdy0","_rev":"d85e4RNWNOToFCQ813A8oh","_type":"sanity.imageAsset","sha1hash":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","_createdAt":"2024-12-23T16:47:36Z","_id":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","extension":"png","metadata":{"palette":{"vibrant":{"title":"#fff","population":0.01,"background":"#bc1934","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"population":6.52,"background":"#58110b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"population":0.96,"background":"#32375a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.05,"background":"#876b71"},"lightVibrant":{"title":"#000","population":1.98,"background":"#d1deea","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.52,"background":"#58110b"},"lightMuted":{"background":"#cbb7a7","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":6.39}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnJtbxS$R5WARP~qofNGV@of-;e-ofoMWV","_type":"sanity.imageMetadata"},"size":1252826,"originalFilename":"Marketing Image (68).png","path":"images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_updatedAt":"2024-12-23T16:47:36Z"}},"showSocialShare":true,"documentGroupMapping":[{"_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526","_type":"reference","_key":"ea0d9592c2e2"}],"seoTag":["COPD management","COPD","COPD prevention","COPD diagnosis","Chronic obstructive pulmonary disease"],"authorMapping":[{"authorType":"expert","_type":"author","_id":"17f58209-caa1-4311-83aa-76c2b68b0431","_updatedAt":"2024-12-23T16:45:03Z","displayName":"M. Bradley Drummond, MD, MHS","_createdAt":"2024-12-23T16:44:59Z","_rev":"nWtwX1K15VoXyHNzqntSRn","url":{"current":"m-bradley-drummond-md-mhs","_type":"slug"}},{"displayName":"MeiLan K. Han, MD, MS","_rev":"Z3pPQn8kInHPss3kunpVqi","_type":"author","_id":"29deaac6-e4ad-4cd2-ab0c-e49222b7e377","_updatedAt":"2024-12-23T16:45:24Z","authorType":"expert","_createdAt":"2024-12-23T16:45:19Z","url":{"current":"meilan-k-han-md-ms","_type":"slug"}},{"_updatedAt":"2024-12-23T16:45:38Z","authorType":"expert","displayName":"Emily Wan, MD MPH","_rev":"kSEheplhqbTVfPV93CoxTR","_type":"author","url":{"current":"emily-wan-md-mph","_type":"slug"},"_createdAt":"2024-12-23T16:45:34Z","_id":"463b5158-ebf7-436c-8d43-5994e7ec000d"},{"displayName":"Ravi Kalhan, MD, MS","_rev":"niOyneYhvNl2SVQWMxfDTV","_type":"author","_updatedAt":"2024-12-23T16:45:56Z","_createdAt":"2024-12-23T16:45:52Z","_id":"2b9dc7d6-c081-417c-9f32-eab0706ea7f6","url":{"current":"ravi-kalhan-md-ms","_type":"slug"},"authorType":"expert"}],"documentGroup":{"_type":"reference","_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526"},"is_visible":true,"_rev":"oufmAAqgdqWHTgEp4VgWRw"},{"_rev":"jxkloFTwbsbZ4yXrpSiEtd","documentGroup":{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference"},"body":[{"_key":"84a7647d1457","videoObject":{"videoDuration":"HCP6M45S","videoDescription":"How BTK Inhibitors Differ From Current CSU Treatment Approaches","_type":"videoDetails","videoTitle":"How BTK Inhibitors Differ From Current CSU Treatment Approaches","thumbnail":{"_type":"image","asset":{"_ref":"image-2f2ebb5d7addd3f41bc7f5cbb3be74452580b7f5-1920x1080-png","_type":"reference"}}},"_type":"video","videoID":"6368429352112","disableAutoPlayVideo":false,"source":"brightcove"},{"_type":"block","style":"normal","_key":"59ac43f909fc","markDefs":[],"children":[{"marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"622afb3d553e","_type":"span"}]},{"_key":"e6b1b8f52516","listItem":"bullet","markDefs":[],"children":[{"marks":[],"text":"How do BTK inhibitors differ from the current treatment approach for chronic spontaneous urticaria (CSU) (antihistamines, omalizumab, immunosuppressants)?\n","_key":"52886f2d341c","_type":"span"}],"level":1,"_type":"block","style":"normal"}],"published":"2025-02-20T13:05:00.000Z","contentCategory":{"name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory"},"summary":"Panelists discuss how Bruton tyrosine kinase (BTK) inhibitors offer a novel upstream approach, in contrast to current treatments that work downstream by either blocking released mediators (antihistamines), neutralizing circulating IgE (omalizumab), or broadly suppressing immune responses (immunosuppressants).","ExcludeFromPubMedXML":false,"_type":"article","documentGroupMapping":[{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference","_key":"a5795c5a2ce2"}],"title":"How BTK Inhibitors Differ From Current CSU Treatment Approaches","_updatedAt":"2025-02-20T13:05:11Z","seoTag":["Chronic Spontaneous Urticaria"],"url":{"_type":"slug","current":"how-btk-inhibitors-differ-from-current-csu-treatment-approaches"},"articleType":"Opinion","authorMapping":[{"firstName":"Giselle","displayName":"Giselle Mosnaim, MD, MS ","_createdAt":"2025-02-10T19:42:46Z","_rev":"NT4ETOVf4DRHVmw78jA9gm","_updatedAt":"2025-02-10T19:42:56Z","lastName":"Mosnaim","authorType":"expert","_type":"author","_id":"ad870360-7628-4fea-8d77-e2924564677e","url":{"current":"giselle-mosnaim-md-ms","_type":"slug"}},{"firstName":"Shyam","lastName":"Joshi","displayName":"Shyam Joshi, MD ","_rev":"wcsTIBGO7X8rh4FCI486MU","_id":"f40abd81-63cc-489d-985a-c1f307da664e","authorType":"expert","_createdAt":"2025-02-10T19:43:23Z","_type":"author","_updatedAt":"2025-02-10T19:43:35Z","url":{"_type":"slug","current":"shyam-joshi-md"}},{"_updatedAt":"2024-03-29T13:58:29Z","url":{"current":"mark-lebwohl-md","_type":"slug"},"lastName":"Lebwohl","displayName":"Mark Lebwohl, MD","_createdAt":"2024-03-29T13:58:29Z","_rev":"wktVmwlv7Py7ixALcRNpYO","_type":"author","firstName":"Mark","_id":"9a2e024a-a67b-4ee6-a1d8-4f70185cdc1b"},{"lastName":"Hawkes","_type":"author","_updatedAt":"2023-06-19T15:53:59Z","url":{"current":"jason-hawkes-md-ms","_type":"slug"},"firstName":"Jason","displayName":"Jason Hawkes, MD, MS","_createdAt":"2023-06-19T15:53:59Z","_rev":"abF4aXKOa4aItNTLQigpeX","_id":"c46cc8d2-54e1-41e4-9719-7aba27a6e9d9"}],"link":"/view/how-btk-inhibitors-differ-from-current-csu-treatment-approaches","thumbnail":{"asset":{"metadata":{"_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"population":2.91,"background":"#373d4d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"title":"#fff","population":2.73,"background":"#aa8081","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightVibrant":{"title":"#000","population":2.99,"background":"#edd4d3","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"foreground":"#fff","title":"#fff","population":0.05,"background":"#261404","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"foreground":"#000","title":"#fff","population":0.09,"background":"#d6b0b5","_type":"sanity.imagePaletteSwatch"},"vibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34,"background":"#94424d"},"dominant":{"population":3.34,"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"height":1080,"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777},"isOpaque":true,"blurHash":"MpIE@SRjS%kCxu~qayX9ofs:jZazoza{RP"},"_createdAt":"2025-02-13T17:04:35Z","_updatedAt":"2025-02-13T17:04:35Z","_id":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","extension":"png","uploadId":"oSnXepOqjz9K6IGvwhhGjyoWZ8FoxhUd","_rev":"XE9vnGgPXscpvWVDknVLRB","_type":"sanity.imageAsset","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","sha1hash":"895ac0390c516bb6677b19ecd0040c5f858f0796","assetId":"895ac0390c516bb6677b19ecd0040c5f858f0796","mimeType":"image/png","path":"images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","size":2172584,"originalFilename":"TL.00_00_24_13.Still002.png"}},"_createdAt":"2025-02-10T20:58:00Z","_id":"907d18f4-bf69-4989-938b-010de74beb3b","taxonomyMapping":[{"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}]},{"parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_type":"taxonomy","summary":[{"style":"normal","_key":"31027e2639fb","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive chronic idiopathic urticaria page is a comprehensive resource for clinical news and insights on CIU. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for urticaria, and more.","_key":"d1966bbb3a12"}],"_type":"block"}],"identifier":"chronic-idiopathic-urticaria","_rev":"QX7y4QewgOajo2HeiHq5KN","name":"Chronic Idiopathic Urticaria","_id":"topic_chronic-idiopathic-urticaria","_updatedAt":"2021-08-20T00:22:05Z"},{"_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z"},{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}],"_type":"block","style":"normal","_key":"8de93ead7686"}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8"}],"is_visible":true,"showSocialShare":true},{"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"articleType":"Opinion","seoTag":["Chronic Spontaneous Urticaria"],"ExcludeFromPubMedXML":false,"_updatedAt":"2025-02-20T13:00:49Z","summary":"Panelists discuss how Bruton tyrosine kinase (BTK) inhibition could effectively treat both autoallergic and autoimmune chronic spontaneous urticaria (CSU).","documentGroup":{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference"},"documentGroupMapping":[{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference","_key":"a5795c5a2ce2"}],"authorMapping":[{"firstName":"Giselle","displayName":"Giselle Mosnaim, MD, MS ","_createdAt":"2025-02-10T19:42:46Z","_rev":"NT4ETOVf4DRHVmw78jA9gm","_updatedAt":"2025-02-10T19:42:56Z","lastName":"Mosnaim","authorType":"expert","_type":"author","_id":"ad870360-7628-4fea-8d77-e2924564677e","url":{"current":"giselle-mosnaim-md-ms","_type":"slug"}},{"_updatedAt":"2025-02-10T19:43:35Z","url":{"_type":"slug","current":"shyam-joshi-md"},"firstName":"Shyam","lastName":"Joshi","displayName":"Shyam Joshi, MD ","_rev":"wcsTIBGO7X8rh4FCI486MU","_id":"f40abd81-63cc-489d-985a-c1f307da664e","authorType":"expert","_createdAt":"2025-02-10T19:43:23Z","_type":"author"},{"firstName":"Mark","_id":"9a2e024a-a67b-4ee6-a1d8-4f70185cdc1b","_updatedAt":"2024-03-29T13:58:29Z","url":{"current":"mark-lebwohl-md","_type":"slug"},"lastName":"Lebwohl","displayName":"Mark Lebwohl, MD","_createdAt":"2024-03-29T13:58:29Z","_rev":"wktVmwlv7Py7ixALcRNpYO","_type":"author"},{"_rev":"abF4aXKOa4aItNTLQigpeX","_id":"c46cc8d2-54e1-41e4-9719-7aba27a6e9d9","lastName":"Hawkes","_type":"author","_updatedAt":"2023-06-19T15:53:59Z","url":{"current":"jason-hawkes-md-ms","_type":"slug"},"firstName":"Jason","displayName":"Jason Hawkes, MD, MS","_createdAt":"2023-06-19T15:53:59Z"}],"url":{"current":"btk-inhibition-as-a-strategy-for-csu-treatment","_type":"slug"},"showSocialShare":true,"is_visible":true,"_type":"article","body":[{"videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-2f2ebb5d7addd3f41bc7f5cbb3be74452580b7f5-1920x1080-png","_type":"reference"}},"videoDuration":"HCP6M45S","videoDescription":"BTK Inhibition as a Strategy for CSU Treatment","_type":"videoDetails","videoTitle":"BTK Inhibition as a Strategy for CSU Treatment"},"_type":"video","videoID":"6368451972112","disableAutoPlayVideo":false,"source":"brightcove","_key":"84a7647d1457"},{"_type":"block","style":"normal","_key":"59ac43f909fc","markDefs":[],"children":[{"_type":"span","marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"622afb3d553e"}]},{"style":"normal","_key":"e6b1b8f52516","markDefs":[],"children":[{"_type":"span","marks":[],"text":"•\tHow would targeting BTK through inhibition be a strategy in the treatment of both IgE (autoallergic) and IgG (autoimmune) CSU?\n•\tCovalent binding enables high and sustained occupancy of BTK without the need for sustained systemic exposure.\n","_key":"c0ea05db679c"}],"_type":"block"}],"title":"BTK Inhibition as a Strategy for CSU Treatment","_createdAt":"2025-02-10T20:55:56Z","_id":"43dd5f84-badf-4269-9748-440b9d021bd8","taxonomyMapping":[{"summary":[{"markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z"},{"parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_type":"taxonomy","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive chronic idiopathic urticaria page is a comprehensive resource for clinical news and insights on CIU. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for urticaria, and more.","_key":"d1966bbb3a12"}],"_type":"block","style":"normal","_key":"31027e2639fb"}],"identifier":"chronic-idiopathic-urticaria","_rev":"QX7y4QewgOajo2HeiHq5KN","name":"Chronic Idiopathic Urticaria","_id":"topic_chronic-idiopathic-urticaria","_updatedAt":"2021-08-20T00:22:05Z"},{"_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX"},{"_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8","summary":[{"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}],"_type":"block","style":"normal","_key":"8de93ead7686","markDefs":[]}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i"}],"published":"2025-02-20T13:00:00.000Z","_rev":"jxkloFTwbsbZ4yXrpSfpTV","thumbnail":{"asset":{"_createdAt":"2025-02-13T17:04:35Z","_updatedAt":"2025-02-13T17:04:35Z","_id":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","extension":"png","uploadId":"oSnXepOqjz9K6IGvwhhGjyoWZ8FoxhUd","_rev":"XE9vnGgPXscpvWVDknVLRB","_type":"sanity.imageAsset","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","sha1hash":"895ac0390c516bb6677b19ecd0040c5f858f0796","assetId":"895ac0390c516bb6677b19ecd0040c5f858f0796","mimeType":"image/png","path":"images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","size":2172584,"originalFilename":"TL.00_00_24_13.Still002.png","metadata":{"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"height":1080,"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777},"isOpaque":true,"blurHash":"MpIE@SRjS%kCxu~qayX9ofs:jZazoza{RP","_type":"sanity.imageMetadata","palette":{"muted":{"foreground":"#fff","title":"#fff","population":2.73,"background":"#aa8081","_type":"sanity.imagePaletteSwatch"},"lightVibrant":{"title":"#000","population":2.99,"background":"#edd4d3","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"title":"#fff","population":0.05,"background":"#261404","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"title":"#fff","population":0.09,"background":"#d6b0b5","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"title":"#fff","population":3.34,"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34,"background":"#94424d"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":2.91,"background":"#373d4d","_type":"sanity.imagePaletteSwatch"}}}}},"link":"/view/btk-inhibition-as-a-strategy-for-csu-treatment"},{"authorMapping":null,"documentGroup":{"_type":"reference","_ref":"7ca9367a-b7bb-4fcc-8d06-bcaf20ab44c0"},"_createdAt":"2025-01-28T16:57:04Z","published":"2025-02-18T13:05:00.000Z","showSocialShare":true,"body":[{"_type":"video","videoID":"6367088856112","disableAutoPlayVideo":false,"source":"brightcove","_key":"791c39ddaa4a","videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","_type":"reference"}},"videoDuration":"HCP3m52s","videoDescription":"Safety Data With Biologics in Atopic Dermatitis","_type":"videoDetails","videoTitle":"Safety Data With Biologics in Atopic Dermatitis"}},{"_key":"c10a68b50e4d","markDefs":[],"children":[{"_type":"span","marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"ae1f355b42a1"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":[],"text":"Please discuss the safety of biologics in AD. Where are we today in understanding the safety of these agents?","_key":"d718caf39e9b"}],"level":1,"_type":"block","style":"normal","_key":"9ac246685bec","listItem":"bullet","markDefs":[]}],"_rev":"SWWZrLXbtmOZqjM3gEZNlO","is_visible":true,"documentGroupMapping":[{"_ref":"7ca9367a-b7bb-4fcc-8d06-bcaf20ab44c0","_type":"reference","_key":"1a893c3005a0"}],"url":{"_type":"slug","current":"safety-data-with-biologics-in-atopic-dermatitis"},"_id":"b9bc870d-494a-4cf6-8975-6622ac811c54","summary":"Panelists discuss the safety of biologics in atopic dermatitis (AD), reviewing current understanding of their safety profiles, including long-term data, adverse events, and the overall risk-benefit analysis for patients using these agents.","ExcludeFromPubMedXML":false,"_type":"article","seoTag":["Atopic dermatitis"],"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"taxonomyMapping":[{"isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[]}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical"},{"_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series"}],"thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnINs}X9RPWURk~qo0WBaeWC-qRjkCjZoe","_type":"sanity.imageMetadata","palette":{"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.73,"background":"#8f191d"},"_type":"sanity.imagePalette","darkMuted":{"population":4.7,"background":"#3b2925","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"population":0,"background":"#b4946c","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"lightVibrant":{"background":"#ecb9a8","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.26},"darkVibrant":{"population":0.02,"background":"#810418","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"population":0.03,"background":"#bacddc","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000"},"vibrant":{"title":"#fff","population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff"}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"uploadId":"tRZtfAPN89t4PeZm1FfsoaO1PgPSPAwP","path":"images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","size":1228069,"assetId":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","_createdAt":"2024-12-24T14:24:15Z","mimeType":"image/png","sha1hash":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","_id":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","originalFilename":"Marketing Image - 2024-12-24T091913.556.png","extension":"png","_rev":"5K24o7vC94LP4crFJHTRn6","_type":"sanity.imageAsset","_updatedAt":"2024-12-24T14:24:15Z"}},"_updatedAt":"2025-01-28T16:58:27Z","articleType":"Opinion","title":"Safety Data With Biologics in Atopic Dermatitis","link":"/view/safety-data-with-biologics-in-atopic-dermatitis"},{"documentGroup":{"_ref":"7ca9367a-b7bb-4fcc-8d06-bcaf20ab44c0","_type":"reference"},"documentGroupMapping":[{"_type":"reference","_key":"1a893c3005a0","_ref":"7ca9367a-b7bb-4fcc-8d06-bcaf20ab44c0"}],"articleType":"Opinion","link":"/view/use-of-combination-therapy-in-atopic-dermatitis","summary":"Panelists discuss the frequency of combination therapy use in managing atopic dermatitis, highlighting its role in enhancing treatment efficacy and addressing multifactorial aspects of the disease in their patient population.","published":"2025-02-18T13:00:00.000Z","taxonomyMapping":[{"isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}]}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical"},{"_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z"}],"_id":"36f6c629-cbb6-4e16-bbe8-f227bdce95e4","url":{"current":"use-of-combination-therapy-in-atopic-dermatitis","_type":"slug"},"_updatedAt":"2025-02-18T15:54:36Z","showSocialShare":true,"_createdAt":"2025-01-28T16:56:09Z","is_visible":true,"thumbnail":{"asset":{"extension":"png","_rev":"5K24o7vC94LP4crFJHTRn6","_type":"sanity.imageAsset","_updatedAt":"2024-12-24T14:24:15Z","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnINs}X9RPWURk~qo0WBaeWC-qRjkCjZoe","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"background":"#3b2925","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":4.7},"muted":{"title":"#fff","population":0,"background":"#b4946c","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"lightVibrant":{"background":"#ecb9a8","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.26},"darkVibrant":{"title":"#fff","population":0.02,"background":"#810418","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"title":"#000","population":0.03,"background":"#bacddc","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"title":"#fff","population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"uploadId":"tRZtfAPN89t4PeZm1FfsoaO1PgPSPAwP","path":"images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","size":1228069,"assetId":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","_createdAt":"2024-12-24T14:24:15Z","mimeType":"image/png","sha1hash":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","_id":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","originalFilename":"Marketing Image - 2024-12-24T091913.556.png"}},"_type":"article","authorMapping":[{"lastName":"Stein Gold","_type":"author","_updatedAt":"2022-04-27T14:18:21Z","url":{"current":"linda-stein-gold-md","_type":"slug"},"firstName":"Linda","displayName":"Linda Stein Gold, MD","_createdAt":"2022-04-27T14:18:21Z","_rev":"IMgnVSbg9NVYxCJ63gNftZ","_id":"76cd476e-ca5b-4ba8-8582-643021fd1ae4"},{"firstName":"Alexandra","lastName":"Golant","displayName":"Alexandra K. Golant, MD","_createdAt":"2022-04-27T14:18:50Z","_rev":"h2V9BXWDd08V4aY6nLN0GR","_id":"4cf3baed-afa1-4a0b-9ee5-2a9267c19e71","_type":"author","_updatedAt":"2022-04-27T14:18:50Z","url":{"current":"alexandra-k-golant-md","_type":"slug"}},{"lastName":"Lio","displayName":"Peter Lio, MD ","_rev":"RNMve0hiapSaZS4aIAOSS6","_type":"author","firstName":"Peter","_createdAt":"2021-09-10T14:33:14Z","company":"Northwestern University Feinberg School of Medicine","_id":"d9e83aaa-e52e-4b4c-8251-da434c87ec17","_updatedAt":"2021-09-10T14:33:14Z","url":{"_type":"slug","current":"peter-lio-md"}},{"firstName":"Jennifer","lastName":"Soung","displayName":"Jennifer Soung, MD","_rev":"1Z6vF4pxH4OlF0724m7fJP","_type":"author","_id":"0d5cce5d-d3c8-4eac-adf6-80e0d28e8a75","_updatedAt":"2023-11-10T14:46:58Z","url":{"current":"jennifer-soung-md","_type":"slug"},"_createdAt":"2023-11-10T14:46:58Z"}],"body":[{"_key":"791c39ddaa4a","videoObject":{"videoDuration":"HCP2m14s","videoDescription":"Use of Combination Therapy in Atopic Dermatitis","_type":"videoDetails","videoTitle":"Use of Combination Therapy in Atopic Dermatitis","thumbnail":{"asset":{"_ref":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","_type":"reference"},"_type":"image"}},"_type":"video","videoID":"6367089459112","disableAutoPlayVideo":false,"source":"brightcove"},{"style":"normal","_key":"c10a68b50e4d","markDefs":[],"children":[{"marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"ae1f355b42a1","_type":"span"}],"_type":"block"},{"level":1,"_type":"block","style":"normal","_key":"9ac246685bec","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"How often are your patients using combination therapy to manage their disease?","_key":"d718caf39e9b"}]}],"contentCategory":{"_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384"},"seoTag":["Atopic dermatitis"],"_rev":"JIsHRd8EUh12asrkPZ8yv9","title":"Use of Combination Therapy in Atopic Dermatitis","ExcludeFromPubMedXML":false},{"ExcludeFromPubMedXML":false,"_id":"6655cff5-8957-4f9f-aff5-ba87ac5cba94","_type":"article","published":"2025-02-17T13:05:00.000Z","showSocialShare":true,"link":"/view/a-primary-care-perspective-on-diagnosing-atopic-dermatitis","taxonomyMapping":[{"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"_key":"2573f14363ee","markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true},{"name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy"},{"identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8","summary":[{"_type":"block","style":"normal","_key":"8de93ead7686","markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}]}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z"},{"identifier":"atopic-dermatitis","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"2sK05ae9cc6f2xw80LsqdL","_id":"topic_atopic-dermatitis","summary":[{"_key":"f61ee45b707b","markDefs":[],"children":[{"text":"On the ","_key":"9faef397dc21","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"95494ef9d956"},{"_type":"span","marks":[],"text":"Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development.","_key":"a55149ee5114"}],"_type":"block","style":"normal"}],"pixelTrackingCode":{"_ref":"e4b5b2a6-8742-42cb-bf97-fa1a8bfd2d53","_type":"reference"},"_type":"taxonomy","name":"Atopic Dermatitis","_updatedAt":"2024-10-23T13:10:35Z"}],"contentCategory":{"_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z"},"thumbnail":{"asset":{"path":"images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","_id":"image-2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080-png","originalFilename":"marketing image (5).png","extension":"png","uploadId":"vUDttLD8iks5qHEhpWfveoGmVDwEqJSn","_rev":"5MymcCPmeJiqJMv8mbGqeF","_type":"sanity.imageAsset","mimeType":"image/png","sha1hash":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","size":1603635,"metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":true,"blurHash":"MlI}I%OEIUW-RP~qaxRPWBWX.8nikCjFj]","_type":"sanity.imageMetadata","palette":{"vibrant":{"population":0.02,"background":"#ba6c34","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.71,"background":"#9f8678"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":0.02,"background":"#345448","_type":"sanity.imagePaletteSwatch"},"muted":{"background":"#9f8678","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.71},"lightVibrant":{"foreground":"#000","title":"#fff","population":0,"background":"#fcbc7c","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"population":4.6,"background":"#74181a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"title":"#fff","population":0.6,"background":"#a8c4d2","_type":"sanity.imagePaletteSwatch","foreground":"#000"}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAALCAYAAAB/Ca1DAAAACXBIWXMAAAPoAAAD6AG1e1JrAAAAFHRFWHRDcmVhdG9yAFByZW1pZXJlIFByb2l7TwQAAAMhSURBVHicJcpNTJMHAIDh766oNzPUQUCzbFWMoIiANNBKaaVWWwpFavltGYWWIVChltJtXzvpLCywtjJZ+WcKehA2MwzZUhEIMVs4OGbmLl62HRbTn4m7vUvc4b08eYUXa+tsLX3LdvQxf758STIWYyeR4E0yyU4iyet4/P9icXbi8bf+b/If3iQSvI7F3v7JeJxXr2L88dffCAuDg8yKIt/4/Xw/PcVWNMrzp095tr7OLxsb/Lq5ybMnj9le/ZHfN9d4sbHG89Uovz2Jsr2yzNb9+2zdWeCnuXnWJ2cRGnOysWSfoDknm/4KHUu3x4guLjEfCvEgEmF1aZFH02NEZ0P8/HCe5akx7g75WY4M88jv5k6FjmmpnCmpjPGzJQile3aj3puCZt9e7IUFPIhMsPLdQ255ReZCQTajP7AyP87yZIDo4gwLM5OMh4Lc/SrAvb5WxvJOEkxNI5yazu0D6QiylF2UpezifMpurHlnmAgMMTYSxG1t5Wafm/nZWaaDAUZcNoa9TkKhEKOjX+Pu6cZVWc5NyQeMvHOIW6npTBzMRJDu24Ny/34uHTiI5eQpPPWNOOqasGkradbpaTPV4myqxXFZR+eVanqtNrrtDiq0RqqKZPRJshjKOMxIWibhQxkIxWlpXFFqsFfW0aPS8omhjuut3Vwzt9KmVmJTSXFWncdpuIinRovPqMPb3ITYdQ2xoxOfwYCokOPLz+XG4SMI8mMnsHR7cQ1MMGxxEmn/mBtfzNDr8dNvvEjAKCNQr8HfoOfLD7VErJeI9LZwLzzIXHgYr6MTa42eTrUcz1EJQr4kB02bSJ0zjNjoItjuxdY/Sn2XF3dtJYPGcwwYVPgMaj43lRG0lOOz1uLru85nn4q02zrQ6Q3UK0rxHM1CyMmUUKCqRa5uwKypx15tpVRjRlVhpremGp9OgUOWj116mp7yswxcVtKhvYC5ugFL41WqTFdRVrVhkOtwvZeFkJv6LtJjeSiPn8FYUExVkYLTWYWU5Mr46FwZruIiWo5LML1/hPbCU4hqBV3FMuwlGlrKjOhVZi5o2jFJ9fRmSPgPvRwVtVqostwAAAAASUVORK5CYII="},"assetId":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937","_createdAt":"2025-02-14T15:20:16Z","_updatedAt":"2025-02-14T15:20:16Z"}},"title":"A Primary Care Perspective on Diagnosing Atopic Dermatitis","url":{"current":"a-primary-care-perspective-on-diagnosing-atopic-dermatitis","_type":"slug"},"_createdAt":"2025-02-14T15:28:15Z","_updatedAt":"2025-02-17T13:05:01Z","summary":"Panelists discuss how they assess atopic dermatitis across all age groups by evaluating clinical history, symptom severity, and physical examination. They consider factors like age-specific presentations, comorbid conditions, and response to treatment for individualized management.","body":[{"_type":"video","videoID":"6368714065112","disableAutoPlayVideo":false,"source":"brightcove","_key":"ad39bb7f4c52","videoObject":{"videoDuration":"HCP2M57S","videoDescription":"Panelists discuss how they assess atopic dermatitis across all age groups by evaluating clinical history, symptom severity, and physical examination. They consider factors like age-specific presentations, comorbid conditions, and response to treatment for individualized management.","_type":"videoDetails","videoTitle":"A Primary Care Perspective on Diagnosing Atopic Dermatitis","thumbnail":{"_type":"image","asset":{"_ref":"image-2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080-png","_type":"reference"}}}},{"children":[{"_key":"9b52774e2d20","_type":"span","marks":["em","strong"],"text":"Video content above in prompted by the following:"}],"_type":"block","style":"normal","_key":"8536b9a0f029","markDefs":[]},{"_key":"19b4986c0683","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Provide perspectives on the how panelists assess atopic dermatitis across all age groups.","_key":"07eb907b08e3"}],"level":1,"_type":"block","style":"normal"}],"authorMapping":[{"authorType":"expert","displayName":"Brad P. Glick, DO, MPH","_createdAt":"2025-01-06T15:34:45Z","_rev":"d85e4RNWNOToFCQ827sKo6","_type":"author","url":{"current":"brad-p-glick-do-mph","_type":"slug"},"_id":"411c27e8-555f-45ea-a398-49c954d75062","_updatedAt":"2025-01-06T15:34:48Z"},{"authorType":"expert","displayName":"Zed Zha, MD, FAAFP","_createdAt":"2025-02-14T14:51:19Z","_type":"author","_updatedAt":"2025-02-14T14:51:19Z","url":{"current":"zed-zha-md-faafp","_type":"slug"},"lastName":"Zha","_rev":"5MymcCPmeJiqJMv8mbDXga","_id":"38501b67-585b-4f63-bd06-16922865f629","firstName":"Zed "},{"firstName":"Charles ","lastName":"Vega","authorType":"expert","_id":"db192129-9391-4b63-9c33-8d1471e66dcb","_updatedAt":"2025-02-14T14:53:32Z","displayName":"Charles Vega, MD, FAAFP","_createdAt":"2025-02-14T14:53:32Z","_rev":"nk0hGN8AuHdSYpy8Ayt6UJ","_type":"author","url":{"current":"charles-vega-md-faafp","_type":"slug"}},{"_type":"author","_updatedAt":"2023-06-19T13:59:49Z","_rev":"hkdPnl63Es19oMLWlTEncJ","_id":"c0271bed-fd84-49b6-9126-a82acb3be026","url":{"current":"mona-shahriari-md-faad","_type":"slug"},"firstName":"Mona","lastName":"Shahriari","displayName":"Mona Shahriari, MD, FAAD","_createdAt":"2023-06-19T13:59:49Z"},{"_id":"db56bca0-f757-4917-ab6d-90e513d6a186","lastName":"Nazareth","_type":"author","_updatedAt":"2025-02-14T14:55:23Z","url":{"current":"michael-r-nazareth-md-phd-faad","_type":"slug"},"firstName":"Michael ","authorType":"expert","displayName":"Michael R. Nazareth, MD, PhD, FAAD","_createdAt":"2025-02-14T14:55:23Z","_rev":"nk0hGN8AuHdSYpy8Ayu87V"}],"documentGroup":{"_ref":"498b12f0-7fa8-4b24-864c-3c635688b05f","_type":"reference"},"articleType":"Opinion","is_visible":true,"_rev":"XE9vnGgPXscpvWVDkye1Nh","documentGroupMapping":[{"_ref":"498b12f0-7fa8-4b24-864c-3c635688b05f","_type":"reference","_key":"d681a52a4660"}],"seoTag":["Atopic dermatitis","shared decision-making","diagnosis","adult patients","pediatric patients","disease severity","EASI","NRS","SCORAD","POEM","BSA","referral","topical JAK inhibitors","biologics","treatment response","adverse effects","primary care","upadacitinib","abrocitinib"]},{"_rev":"JIsHRd8EUh12asrkPZ2SVj","articleType":"Opinion","_type":"article","link":"/view/considerations-for-switching-systemic-agents-in-atopic-dermatitis","authorMapping":null,"seoTag":["atopic dermatitis"],"documentGroupMapping":[{"_key":"7f2b82195dc2","_ref":"d6689f68-2f04-49f5-b81b-5b0f13f60bf2","_type":"reference"}],"showSocialShare":true,"thumbnail":{"asset":{"uploadId":"670OHsVYqwO0HYIucVdjSWngIxEQY6S3","_type":"sanity.imageAsset","sha1hash":"0878bfa7cd08e89066336e7089ede6c234290179","_createdAt":"2025-01-03T19:58:20Z","_id":"image-0878bfa7cd08e89066336e7089ede6c234290179-1920x1080-png","originalFilename":"Marketing Image - 2025-01-03T145812.788.png","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","path":"images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","size":1418782,"assetId":"0878bfa7cd08e89066336e7089ede6c234290179","_updatedAt":"2025-01-03T19:58:20Z","extension":"png","metadata":{"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"aspectRatio":1.7777777777777777,"height":1080,"_type":"sanity.imageDimensions","width":1920},"isOpaque":true,"blurHash":"MmH_MmR*i_j=M|~qjERjaya}.8a#W;aeoJ","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"title":"#fff","population":6.51,"background":"#54413a","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"muted":{"background":"#8f7f75","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.55},"lightVibrant":{"foreground":"#000","title":"#fff","population":0.71,"background":"#d7bda3","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.08,"background":"#59120f"},"lightMuted":{"background":"#b7867b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.88},"vibrant":{"foreground":"#fff","title":"#fff","population":5.32,"background":"#9d3030","_type":"sanity.imagePaletteSwatch"},"dominant":{"foreground":"#fff","title":"#fff","population":7.08,"background":"#59120f","_type":"sanity.imagePaletteSwatch"}}},"_rev":"5K24o7vC94LP4crFKji536","mimeType":"image/png"}},"is_visible":true,"documentGroup":{"_type":"reference","_ref":"d6689f68-2f04-49f5-b81b-5b0f13f60bf2"},"_id":"c33f9111-e780-4a88-924c-c0304e02fea5","published":"2025-02-17T13:05:00.000Z","body":[{"videoID":"6366923059112","disableAutoPlayVideo":false,"source":"brightcove","_key":"12a21cb69bcc","videoObject":{"videoDuration":"HPC7M45S","videoDescription":"Considerations for Switching Systemic Agents in Atopic Dermatitis","_type":"videoDetails","videoTitle":"Considerations for Switching Systemic Agents in Atopic Dermatitis","thumbnail":{"_type":"image","asset":{"_ref":"image-0878bfa7cd08e89066336e7089ede6c234290179-1920x1080-png","_type":"reference"}}},"_type":"video"},{"markDefs":[],"children":[{"_type":"span","marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"488d3f19dea3"}],"_type":"block","style":"normal","_key":"061345922d5b"},{"_type":"block","style":"normal","_key":"c623927f6489","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"How prevalent is treatment-refractory moderate to severe atopic dermatitis?","_key":"e18610126dd5"}],"level":1},{"children":[{"marks":[],"text":"What are other reasons for treatment failure (eg, intolerance, inability to use high-potency topical agents)?","_key":"1d7f5ea94e66","_type":"span"}],"level":1,"_type":"block","style":"normal","_key":"62d66b99b013","listItem":"bullet","markDefs":[]},{"listItem":"bullet","markDefs":[],"children":[{"marks":[],"text":"When do you consider adding or switching agents?","_key":"7aa756cbe794","_type":"span"}],"level":1,"_type":"block","style":"normal","_key":"a4d3b2ae1d01"},{"_key":"703fdc843760","listItem":"bullet","markDefs":[],"children":[{"_key":"91b2ff337907","_type":"span","marks":[],"text":"What other treatment options exist for pediatric atopic dermatitis?"}],"level":1,"_type":"block","style":"normal"},{"_key":"7e65a6ebd4d8","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"How do you determine which treatment to switch to?","_key":"77d01d6dcd0d"}],"level":1,"_type":"block","style":"normal"},{"_key":"cfbdf98743b7","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Biologic to JAK inhibitor: Blauvelt 2023, Keow \u0026 Abu-Hilal 2024, JADE EXTEND, Shi 2022","_key":"2c3f8440e290"}],"level":1,"_type":"block","style":"normal"}],"title":"Considerations for Switching Systemic Agents in Atopic Dermatitis","_createdAt":"2025-01-30T15:40:07Z","summary":"Panelists discuss the prevalence of treatment-refractory moderate to severe atopic dermatitis, noting factors such as intolerance or inability to use high-potency topical agents as common reasons for treatment failure, and emphasize the importance of considering alternative agents or switching treatments when necessary, particularly in pediatric patients, with biologics and Janus kinase (JAK) inhibitors being key options as evidenced by studies such as Blauvelt 2023, Keow \u0026 Abu-Hilal 2024 , and JADE EXTEND.","ExcludeFromPubMedXML":false,"_updatedAt":"2025-02-18T15:33:20Z","taxonomyMapping":[{"isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical"},{"summary":[{"_key":"f61ee45b707b","markDefs":[],"children":[{"text":"On the ","_key":"9faef397dc21","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"95494ef9d956"},{"_type":"span","marks":[],"text":"Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development.","_key":"a55149ee5114"}],"_type":"block","style":"normal"}],"pixelTrackingCode":{"_ref":"e4b5b2a6-8742-42cb-bf97-fa1a8bfd2d53","_type":"reference"},"_type":"taxonomy","name":"Atopic Dermatitis","_updatedAt":"2024-10-23T13:10:35Z","identifier":"atopic-dermatitis","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"2sK05ae9cc6f2xw80LsqdL","_id":"topic_atopic-dermatitis"},{"_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c"}],"url":{"current":"considerations-for-switching-systemic-agents-in-atopic-dermatitis","_type":"slug"},"contentCategory":{"_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u"}},{"_createdAt":"2025-01-30T15:37:27Z","thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","path":"images/0vv8moc6/hcplive/0878bfa7cd08e89066336e7089ede6c234290179-1920x1080.png","size":1418782,"assetId":"0878bfa7cd08e89066336e7089ede6c234290179","_updatedAt":"2025-01-03T19:58:20Z","extension":"png","metadata":{"palette":{"muted":{"title":"#fff","population":6.55,"background":"#8f7f75","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightVibrant":{"foreground":"#000","title":"#fff","population":0.71,"background":"#d7bda3","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.08,"background":"#59120f"},"lightMuted":{"foreground":"#fff","title":"#fff","population":1.88,"background":"#b7867b","_type":"sanity.imagePaletteSwatch"},"vibrant":{"foreground":"#fff","title":"#fff","population":5.32,"background":"#9d3030","_type":"sanity.imagePaletteSwatch"},"dominant":{"foreground":"#fff","title":"#fff","population":7.08,"background":"#59120f","_type":"sanity.imagePaletteSwatch"},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.51,"background":"#54413a"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"aspectRatio":1.7777777777777777,"height":1080,"_type":"sanity.imageDimensions","width":1920},"isOpaque":true,"blurHash":"MmH_MmR*i_j=M|~qjERjaya}.8a#W;aeoJ","_type":"sanity.imageMetadata"},"_rev":"5K24o7vC94LP4crFKji536","mimeType":"image/png","uploadId":"670OHsVYqwO0HYIucVdjSWngIxEQY6S3","_type":"sanity.imageAsset","sha1hash":"0878bfa7cd08e89066336e7089ede6c234290179","_createdAt":"2025-01-03T19:58:20Z","_id":"image-0878bfa7cd08e89066336e7089ede6c234290179-1920x1080-png","originalFilename":"Marketing Image - 2025-01-03T145812.788.png"}},"documentGroupMapping":[{"_ref":"d6689f68-2f04-49f5-b81b-5b0f13f60bf2","_type":"reference","_key":"7f2b82195dc2"}],"title":"Expectations for Efficacy and Duration of Response With Systemic Atopic Dermatitis Treatments","url":{"current":"expectations-for-efficacy-and-duration-of-response-with-systemic-atopic-dermatitis-treatments","_type":"slug"},"showSocialShare":true,"is_visible":true,"summary":"Panelists discuss treatment expectations for newer systemic agents, highlighting data on efficacy onset and persistence, including rapid improvement in pruritus with dupilumab by week 2 (SOLO trials), early Investigator Global Assessment (IGA) and Eczema Area and Severity Index (EASI)-75 improvement with lebrikizumab by week 2 to 4 (ADvocate trials), and EASI-75 improvement with tralokinumab by week 4 (ECZTRA 6 trial), emphasizing the importance of setting realistic expectations with patients and caregivers regarding the onset of action and duration of treatment.","published":"2025-02-17T13:00:00.000Z","articleType":"Opinion","_rev":"JIsHRd8EUh12asrkPZ28cR","ExcludeFromPubMedXML":false,"taxonomyMapping":[{"summary":[{"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[]}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z"},{"summary":[{"_key":"f61ee45b707b","markDefs":[],"children":[{"text":"On the ","_key":"9faef397dc21","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"95494ef9d956"},{"_type":"span","marks":[],"text":"Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development.","_key":"a55149ee5114"}],"_type":"block","style":"normal"}],"pixelTrackingCode":{"_ref":"e4b5b2a6-8742-42cb-bf97-fa1a8bfd2d53","_type":"reference"},"_type":"taxonomy","name":"Atopic Dermatitis","_updatedAt":"2024-10-23T13:10:35Z","identifier":"atopic-dermatitis","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"2sK05ae9cc6f2xw80LsqdL","_id":"topic_atopic-dermatitis"},{"_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series"}],"contentCategory":{"_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u"},"link":"/view/expectations-for-efficacy-and-duration-of-response-with-systemic-atopic-dermatitis-treatments","_updatedAt":"2025-02-18T15:32:18Z","_type":"article","body":[{"_key":"12a21cb69bcc","videoObject":{"videoDuration":"HPC7M45S","videoDescription":"Expectations for Efficacy and Duration of Response With Systemic Atopic Dermatitis Treatments","_type":"videoDetails","videoTitle":"Expectations for Efficacy and Duration of Response With Systemic Atopic Dermatitis Treatments","thumbnail":{"_type":"image","asset":{"_ref":"image-0878bfa7cd08e89066336e7089ede6c234290179-1920x1080-png","_type":"reference"}}},"_type":"video","videoID":"6366921318112","disableAutoPlayVideo":false,"source":"brightcove"},{"style":"normal","_key":"061345922d5b","markDefs":[],"children":[{"text":"Video content above is prompted by the following:","_key":"488d3f19dea3","_type":"span","marks":["strong","em"]}],"_type":"block"},{"_type":"block","style":"normal","_key":"a22d965f57c5","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Let’s shift now to treatment expectations. What are the data about efficacy onset and persistence when considering these newer systemic agents?","_key":"7a370567d50a"}],"level":1},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"How do you set expectations with patients starting on systemic treatment and their caregivers in terms of onset of action and duration of treatment?","_key":"381dc2683e2e"}],"level":1,"_type":"block","style":"normal","_key":"33fd80b8d679","listItem":"bullet"},{"level":1,"_type":"block","style":"normal","_key":"dd67bf313f24","listItem":"bullet","markDefs":[],"children":[{"text":"Dupilumab in the SOLO trials showed improvement on Peak Pruritus Numerical Rating Scale score at week 2 (in adults).","_key":"5670af3dbbf1","_type":"span","marks":[]}]},{"style":"normal","_key":"933c26ac02a9","listItem":"bullet","markDefs":[],"children":[{"_key":"ebc04bcadef3","_type":"span","marks":[],"text":"Lebrikizumab in the ADvocate trials showed some IGA improvement at week 4 and some EASI-75 improvement at week 2."}],"level":1,"_type":"block"},{"_key":"5a0515010b14","listItem":"bullet","markDefs":[],"children":[{"_key":"1ea78a8d617d","_type":"span","marks":[],"text":"Tralokinumab in the ECZTRA 6 trial showed some EASI-75 improvement at 4 weeks (in adolescents).\n"}],"level":1,"_type":"block","style":"normal"}],"authorMapping":null,"seoTag":["atopic dermatitis"],"documentGroup":{"_ref":"d6689f68-2f04-49f5-b81b-5b0f13f60bf2","_type":"reference"},"_id":"b318d2c0-e681-4bfd-94fd-04a990cc42d0"},{"taxonomyMapping":[{"summary":[{"markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z"},{"_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series"},{"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8","summary":[{"style":"normal","_key":"8de93ead7686","markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}],"_type":"block"}]},{"identifier":"atopic-dermatitis","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"2sK05ae9cc6f2xw80LsqdL","_id":"topic_atopic-dermatitis","summary":[{"markDefs":[],"children":[{"text":"On the ","_key":"9faef397dc21","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"95494ef9d956"},{"_type":"span","marks":[],"text":"Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development.","_key":"a55149ee5114"}],"_type":"block","style":"normal","_key":"f61ee45b707b"}],"pixelTrackingCode":{"_ref":"e4b5b2a6-8742-42cb-bf97-fa1a8bfd2d53","_type":"reference"},"_type":"taxonomy","name":"Atopic Dermatitis","_updatedAt":"2024-10-23T13:10:35Z"}],"published":"2025-02-17T13:00:00.000Z","documentGroupMapping":[{"_ref":"498b12f0-7fa8-4b24-864c-3c635688b05f","_type":"reference","_key":"d681a52a4660"}],"_updatedAt":"2025-02-17T13:00:11Z","title":"Considerations for Diagnosis of Atopic Dermatitis in Adults","summary":"Panelists discuss how adult atopic dermatitis diagnosis relies on clinical presentation of chronic, pruritic, and eczematous lesions with characteristic distribution patterns. Unlike children, adults show more lichenified plaques and predominant hand/foot involvement. Key diagnostic criteria include personal/family history of atopy and chronic/relapsing course. No definitive test exists.","_rev":"5MymcCPmeJiqJMv8mkXSgM","contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"thumbnail":{"asset":{"path":"images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","_id":"image-2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080-png","originalFilename":"marketing image (5).png","extension":"png","uploadId":"vUDttLD8iks5qHEhpWfveoGmVDwEqJSn","_rev":"5MymcCPmeJiqJMv8mbGqeF","_type":"sanity.imageAsset","mimeType":"image/png","sha1hash":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080.png","size":1603635,"metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":true,"blurHash":"MlI}I%OEIUW-RP~qaxRPWBWX.8nikCjFj]","_type":"sanity.imageMetadata","palette":{"darkVibrant":{"foreground":"#fff","title":"#fff","population":4.6,"background":"#74181a","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"background":"#a8c4d2","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.6},"vibrant":{"title":"#fff","population":0.02,"background":"#ba6c34","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.71,"background":"#9f8678"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":0.02,"background":"#345448","_type":"sanity.imagePaletteSwatch"},"muted":{"background":"#9f8678","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.71},"lightVibrant":{"background":"#fcbc7c","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"assetId":"2515e0e13de1c439ac26dcc8f51a17e5cbd8d937","_createdAt":"2025-02-14T15:20:16Z","_updatedAt":"2025-02-14T15:20:16Z"}},"seoTag":["Atopic dermatitis","shared decision-making","diagnosis","adult patients","pediatric patients","disease severity","EASI","NRS","SCORAD","POEM","BSA","referral","topical JAK inhibitors","biologics","treatment response","adverse effects","primary care","upadacitinib","abrocitinib"],"authorMapping":[{"authorType":"expert","displayName":"Brad P. Glick, DO, MPH","_createdAt":"2025-01-06T15:34:45Z","_rev":"d85e4RNWNOToFCQ827sKo6","_type":"author","url":{"current":"brad-p-glick-do-mph","_type":"slug"},"_id":"411c27e8-555f-45ea-a398-49c954d75062","_updatedAt":"2025-01-06T15:34:48Z"},{"_id":"38501b67-585b-4f63-bd06-16922865f629","firstName":"Zed ","authorType":"expert","displayName":"Zed Zha, MD, FAAFP","_createdAt":"2025-02-14T14:51:19Z","_type":"author","_updatedAt":"2025-02-14T14:51:19Z","url":{"current":"zed-zha-md-faafp","_type":"slug"},"lastName":"Zha","_rev":"5MymcCPmeJiqJMv8mbDXga"},{"firstName":"Charles ","lastName":"Vega","authorType":"expert","_id":"db192129-9391-4b63-9c33-8d1471e66dcb","_updatedAt":"2025-02-14T14:53:32Z","displayName":"Charles Vega, MD, FAAFP","_createdAt":"2025-02-14T14:53:32Z","_rev":"nk0hGN8AuHdSYpy8Ayt6UJ","_type":"author","url":{"current":"charles-vega-md-faafp","_type":"slug"}},{"_rev":"hkdPnl63Es19oMLWlTEncJ","_id":"c0271bed-fd84-49b6-9126-a82acb3be026","url":{"current":"mona-shahriari-md-faad","_type":"slug"},"firstName":"Mona","lastName":"Shahriari","displayName":"Mona Shahriari, MD, FAAD","_createdAt":"2023-06-19T13:59:49Z","_type":"author","_updatedAt":"2023-06-19T13:59:49Z"},{"_id":"db56bca0-f757-4917-ab6d-90e513d6a186","lastName":"Nazareth","_type":"author","_updatedAt":"2025-02-14T14:55:23Z","url":{"current":"michael-r-nazareth-md-phd-faad","_type":"slug"},"firstName":"Michael ","authorType":"expert","displayName":"Michael R. Nazareth, MD, PhD, FAAD","_createdAt":"2025-02-14T14:55:23Z","_rev":"nk0hGN8AuHdSYpy8Ayu87V"}],"documentGroup":{"_ref":"498b12f0-7fa8-4b24-864c-3c635688b05f","_type":"reference"},"body":[{"videoID":"6368713362112","disableAutoPlayVideo":false,"source":"brightcove","_key":"ad39bb7f4c52","videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-2515e0e13de1c439ac26dcc8f51a17e5cbd8d937-1920x1080-png","_type":"reference"}},"videoDuration":"HCP6M13S","videoDescription":"Panelists discuss how adult atopic dermatitis diagnosis relies on clinical presentation of chronic, pruritic, and eczematous lesions with characteristic distribution patterns. Unlike children, adults show more lichenified plaques and predominant hand/foot involvement. Key diagnostic criteria include personal/family history of atopy and chronic/relapsing course. No definitive test exists.","_type":"videoDetails","videoTitle":"Considerations for Diagnosis of Atopic Dermatitis in Adults"},"_type":"video"},{"markDefs":[],"children":[{"_key":"9b52774e2d20","_type":"span","marks":["em","strong"],"text":"Video content above in prompted by the following:"}],"_type":"block","style":"normal","_key":"8536b9a0f029"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Discuss the diagnosis of atopic dermatitis in adults, specifically what’s needed to make the diagnosis and the considerations in adults vs pediatric patients.","_key":"1e3f934f0df5"}],"level":1,"_type":"block","style":"normal","_key":"33f750e6efad","listItem":"bullet"}],"_type":"article","is_visible":true,"_id":"f418306a-7db8-4a0e-909c-46a6bbd5690b","link":"/view/considerations-for-diagnosis-of-atopic-dermatitis-in-adults","ExcludeFromPubMedXML":false,"url":{"current":"considerations-for-diagnosis-of-atopic-dermatitis-in-adults","_type":"slug"},"articleType":"Opinion","_createdAt":"2025-02-14T14:47:56Z","showSocialShare":true},{"published":"2025-02-14T13:05:00.000Z","authorMapping":[{"displayName":"M. Bradley Drummond, MD, MHS","_createdAt":"2024-12-23T16:44:59Z","_rev":"nWtwX1K15VoXyHNzqntSRn","url":{"current":"m-bradley-drummond-md-mhs","_type":"slug"},"authorType":"expert","_type":"author","_id":"17f58209-caa1-4311-83aa-76c2b68b0431","_updatedAt":"2024-12-23T16:45:03Z"},{"displayName":"MeiLan K. Han, MD, MS","_rev":"Z3pPQn8kInHPss3kunpVqi","_type":"author","_id":"29deaac6-e4ad-4cd2-ab0c-e49222b7e377","_updatedAt":"2024-12-23T16:45:24Z","authorType":"expert","_createdAt":"2024-12-23T16:45:19Z","url":{"current":"meilan-k-han-md-ms","_type":"slug"}},{"authorType":"expert","displayName":"Emily Wan, MD MPH","_rev":"kSEheplhqbTVfPV93CoxTR","_type":"author","url":{"current":"emily-wan-md-mph","_type":"slug"},"_createdAt":"2024-12-23T16:45:34Z","_id":"463b5158-ebf7-436c-8d43-5994e7ec000d","_updatedAt":"2024-12-23T16:45:38Z"},{"_type":"author","_updatedAt":"2024-12-23T16:45:56Z","_createdAt":"2024-12-23T16:45:52Z","_id":"2b9dc7d6-c081-417c-9f32-eab0706ea7f6","url":{"current":"ravi-kalhan-md-ms","_type":"slug"},"authorType":"expert","displayName":"Ravi Kalhan, MD, MS","_rev":"niOyneYhvNl2SVQWMxfDTV"}],"summary":"Panelists discuss how individualized chronic obstructive pulmonary disease (COPD) maintenance therapy considers symptom severity, exacerbation risk, and eosinophil levels. Dupilumab and ensifentrine require adherence to prescribed dosing for efficacy and safety.","documentGroupMapping":[{"_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526","_type":"reference","_key":"ea0d9592c2e2"}],"url":{"current":"maintenance-therapy-and-adherence-to-copd-treatment","_type":"slug"},"contentCategory":{"_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z"},"_id":"7f57f576-c44c-4579-b4b5-b71fa5205310","_type":"article","is_visible":true,"_createdAt":"2025-01-20T14:33:29Z","seoTag":["COPD management","COPD","COPD prevention","COPD diagnosis","Chronic obstructive pulmonary disease"],"showSocialShare":true,"articleType":"Opinion","link":"/view/maintenance-therapy-and-adherence-to-copd-treatment","ExcludeFromPubMedXML":false,"thumbnail":{"asset":{"uploadId":"oUch4WEsQdZlRPM2Xzm6fyEM7fUwxdy0","_rev":"d85e4RNWNOToFCQ813A8oh","_type":"sanity.imageAsset","sha1hash":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","_createdAt":"2024-12-23T16:47:36Z","_id":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","extension":"png","metadata":{"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnJtbxS$R5WARP~qofNGV@of-;e-ofoMWV","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"background":"#32375a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.96},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.05,"background":"#876b71"},"lightVibrant":{"population":1.98,"background":"#d1deea","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.52,"background":"#58110b"},"lightMuted":{"foreground":"#000","title":"#fff","population":6.39,"background":"#cbb7a7","_type":"sanity.imagePaletteSwatch"},"vibrant":{"foreground":"#fff","title":"#fff","population":0.01,"background":"#bc1934","_type":"sanity.imagePaletteSwatch"},"dominant":{"population":6.52,"background":"#58110b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"}},"hasAlpha":true},"size":1252826,"originalFilename":"Marketing Image (68).png","path":"images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_updatedAt":"2024-12-23T16:47:36Z","mimeType":"image/png","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","assetId":"413626ed9a43092d8e8b54e779a66a9c0ad02c32"}},"documentGroup":{"_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526","_type":"reference"},"_updatedAt":"2025-01-20T14:40:07Z","taxonomyMapping":[{"name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy"},{"_id":"091c96e7-e15c-4b96-8894-79fa589e08d8","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}],"_type":"block","style":"normal","_key":"8de93ead7686"}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange"},{"_updatedAt":"2021-11-10T19:26:47Z","summary":[{"style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532"},{"_createdAt":"2020-05-20T18:09:49Z","_rev":"duatTUEfMZ8Ma3bwePOSKv","_type":"taxonomy","name":"COPD","identifier":"copd","_id":"topic_copd","_updatedAt":"2021-03-12T23:09:23Z","summary":[{"markDefs":[],"children":[{"_key":"a93ed19c195c","_type":"span","marks":[],"text":"On the "},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"a717dd6a302d"},{"marks":[],"text":"COPD condition center page, resources on the topics of medical news and expert insight into chronic obstructive pulmonary disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on COPD research, treatment, and drug development.","_key":"fa4d38c12dca","_type":"span"}],"_type":"block","style":"normal","_key":"002ff14623bd"}],"parent":{"_ref":"topic_pulmonology","_type":"reference"}}],"body":[{"source":"brightcove","_key":"5f8621b98ebd","videoObject":{"videoDescription":"Panelists discuss how individualized chronic obstructive pulmonary disease (COPD) maintenance therapy considers symptom severity, exacerbation risk, and eosinophil levels. Dupilumab and ensifentrine require adherence to prescribed dosing for efficacy and safety.","_type":"videoDetails","videoTitle":"Maintenance Therapy and Adherence to COPD Treatment","thumbnail":{"_type":"image","asset":{"_ref":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","_type":"reference"}},"videoDuration":"HCP6m27s"},"_type":"video","videoID":"6367091666112","disableAutoPlayVideo":false},{"_key":"416ae49ca90d","markDefs":[],"children":[{"_type":"span","marks":["em","strong"],"text":"Video content above is prompted by the following:","_key":"f4edcaa9d1a30"}],"_type":"block","style":"normal"},{"listItem":"bullet","markDefs":[],"children":[{"_key":"67afd3c5ede6","_type":"span","marks":[],"text":"What are key considerations when selecting individualized maintenance therapy for COPD?"}],"level":1,"_type":"block","style":"normal","_key":"82e88f6586e9"},{"listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"What are the dosing and administration recommendations for dupilumab and ensifentrine? Is treatment adherence a concern with either agent?","_key":"594136062a76"}],"level":1,"_type":"block","style":"normal","_key":"e780ee9368f8"}],"_rev":"PHYRau07g0l5Y4L0XCWn7q","title":"Maintenance Therapy and Adherence to COPD Treatment"},{"_rev":"PHYRau07g0l5Y4L0XCUKSi","url":{"current":"ensifentrine-enhance-trials-in-copd","_type":"slug"},"body":[{"_type":"video","videoID":"6367090885112","disableAutoPlayVideo":false,"source":"brightcove","_key":"5f8621b98ebd","videoObject":{"videoTitle":"Ensifentrine (ENHANCE Trials) in COPD","thumbnail":{"asset":{"_ref":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","_type":"reference"},"_type":"image"},"videoDuration":"HCP4m46s","videoDescription":"Panelists discuss how the ENHANCE trials assessed ensifentrine in patients with chronic obstructive pulmonary disease (COPD) with moderate-to-severe airflow obstruction and a history of exacerbations. Outcomes showed improved lung function and reduced exacerbations. Clinically, ensifentrine may be used as monotherapy or an add-on, addressing diverse patient needs.","_type":"videoDetails"}},{"children":[{"_type":"span","marks":["em","strong"],"text":"Video content above is prompted by the following:","_key":"f4edcaa9d1a30"}],"_type":"block","style":"normal","_key":"416ae49ca90d","markDefs":[]},{"_key":"a910b4713c83","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Ensifentrine is recommended in the 2025 GOLD Report as a bronchodilator to improve dyspnea. Ensifentrine is also suggested as a potential anti-inflammatory therapy in stable COPD.","_key":"8788de4de8eb"}],"level":1,"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"158c327c5670","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"What were the main patient eligibility criteria and clinical outcomes in the ENHANCE trials?","_key":"97f4b77ad803"}],"level":2},{"_key":"bd50e6fd45c5","listItem":"bullet","markDefs":[],"children":[{"marks":[],"text":"How do you anticipate that ensifentrine will be used in clinical practice (ie, monotherapy, add-on, both)?","_key":"f40011833a9e","_type":"span"}],"level":2,"_type":"block","style":"normal"}],"documentGroup":{"_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526","_type":"reference"},"published":"2025-02-14T13:00:00.000Z","summary":"Panelists discuss how the ENHANCE trials assessed ensifentrine in patients with chronic obstructive pulmonary disease (COPD) with moderate-to-severe airflow obstruction and a history of exacerbations. Outcomes showed improved lung function and reduced exacerbations. Clinically, ensifentrine may be used as monotherapy or an add-on, addressing diverse patient needs.","link":"/view/ensifentrine-enhance-trials-in-copd","_updatedAt":"2025-01-20T14:30:42Z","showSocialShare":true,"authorMapping":[{"displayName":"M. Bradley Drummond, MD, MHS","_createdAt":"2024-12-23T16:44:59Z","_rev":"nWtwX1K15VoXyHNzqntSRn","url":{"current":"m-bradley-drummond-md-mhs","_type":"slug"},"authorType":"expert","_type":"author","_id":"17f58209-caa1-4311-83aa-76c2b68b0431","_updatedAt":"2024-12-23T16:45:03Z"},{"_createdAt":"2024-12-23T16:45:19Z","url":{"current":"meilan-k-han-md-ms","_type":"slug"},"displayName":"MeiLan K. Han, MD, MS","_rev":"Z3pPQn8kInHPss3kunpVqi","_type":"author","_id":"29deaac6-e4ad-4cd2-ab0c-e49222b7e377","_updatedAt":"2024-12-23T16:45:24Z","authorType":"expert"},{"_rev":"kSEheplhqbTVfPV93CoxTR","_type":"author","url":{"current":"emily-wan-md-mph","_type":"slug"},"_createdAt":"2024-12-23T16:45:34Z","_id":"463b5158-ebf7-436c-8d43-5994e7ec000d","_updatedAt":"2024-12-23T16:45:38Z","authorType":"expert","displayName":"Emily Wan, MD MPH"},{"_type":"author","_updatedAt":"2024-12-23T16:45:56Z","_createdAt":"2024-12-23T16:45:52Z","_id":"2b9dc7d6-c081-417c-9f32-eab0706ea7f6","url":{"current":"ravi-kalhan-md-ms","_type":"slug"},"authorType":"expert","displayName":"Ravi Kalhan, MD, MS","_rev":"niOyneYhvNl2SVQWMxfDTV"}],"ExcludeFromPubMedXML":false,"title":"Ensifentrine (ENHANCE Trials) in COPD","is_visible":true,"thumbnail":{"asset":{"mimeType":"image/png","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","assetId":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","uploadId":"oUch4WEsQdZlRPM2Xzm6fyEM7fUwxdy0","_rev":"d85e4RNWNOToFCQ813A8oh","_type":"sanity.imageAsset","sha1hash":"413626ed9a43092d8e8b54e779a66a9c0ad02c32","_createdAt":"2024-12-23T16:47:36Z","_id":"image-413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080-png","extension":"png","metadata":{"isOpaque":false,"blurHash":"MnJtbxS$R5WARP~qofNGV@of-;e-ofoMWV","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"background":"#32375a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.96},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.05,"background":"#876b71"},"lightVibrant":{"background":"#d1deea","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000","population":1.98},"darkVibrant":{"population":6.52,"background":"#58110b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"title":"#fff","population":6.39,"background":"#cbb7a7","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"population":0.01,"background":"#bc1934","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"dominant":{"foreground":"#fff","title":"#fff","population":6.52,"background":"#58110b","_type":"sanity.imagePaletteSwatch"}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAALCAYAAAB/Ca1DAAAACXBIWXMAAAPoAAAD6AG1e1JrAAAAFHRFWHRDcmVhdG9yAFByZW1pZXJlIFByb2l7TwQAAAMqSURBVHicZY9fUNMFAMf32l0YeHapcyRLIC7v6gHjFGflDEMZhBOG4MZgQ/k3Fuu4XyiROnHDaRsIQxoCg/hzyiyBQESB9pPhpKs7O5HMF1/quus82Lp44NinM3vr4fPwffnc5yt5MhvgwcgoC34/vz99Snhpib9DoRcsL/+PlVCIlXCYlVD43/3X0jLh5RDPni3x2x9/IhlxOblut3Gzw8P85CQL9+Z4NBdgMRDg8f37/Dr/A4v3gjy6K/J41s8v4gwL03dYnJlmcWaKn29N8ODGCD8NXiPY049EeDeZ+vd247FYuD3kQ/xujEmvl9sdHQRHRvlx2o84PMLU1x78vW5uuBrwCJ/Qf6qW8WY7w7YvuFpcxOC+j+jbo0RSuP4VKuJicVeZEb8PIIpBhlrbGTrvZO7mFA8fPiEoziJ+62VmoIn2OjNCzsdYi/IZtJ3AZxXoVqXTGRdPj3QrEt36dZRuldFsqmZsQqS77zqfV9VwprKG9pYuJqbnuesPMDvcy/iVRs6V6ihPS8OkOoi71oTvrIA3K4MueQL9W+RI8mOiOCaT0qgtotN5GaG8msN701F/mEX+4UIcjja+6b+Gz2XD81klNdmZ6BXvU6hMw1pRRm+9QFemig55PN3SOCSa6ChKtmzGkXeEXrsDm6ka44FsshQZqJQ5nKxpiFxquLh22miI1OqOIuiNWLQGhONVXLTa6W48T2eOhjZ5Aq2bYl8IjbFSWowGbvX10dPUQn25hWOaMjLSislWmyK6vLJVU0Hhmq3uBJddLtrsjfS52xgf8jHh9TJYZKB1WxLOjTIkOdFR6GWbcZUYGRsYwO1o4lOjhZJ8MynJaqSy1MjbSYrV47lH1prOncb95QUu1NXxlc3GaHs7d5xOrmp1uOOTaHle+FyolW7kjPoQV6xnOVliRqPM5aBCQ8LrHxD9UmIkccMbq3m7Uteqc9RU5BVgyNVSml/MKUMpnvJKPKpMLskT/7scs46C1zZg3pFMfYaKsl37yH5zJ3u3pfLWq8nEv5wQSYmRrmni5JGS7dspemcH+t37OarYj36PEiH9ALaUnThlcpo3xfIP2VAjnZwwjFIAAAAASUVORK5CYII=","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080}},"size":1252826,"originalFilename":"Marketing Image (68).png","path":"images/0vv8moc6/hcplive/413626ed9a43092d8e8b54e779a66a9c0ad02c32-1920x1080.png","_updatedAt":"2024-12-23T16:47:36Z"}},"_createdAt":"2025-01-20T14:29:50Z","_id":"eec15d87-9954-483d-97d1-3f7bf433c35e","_type":"article","contentCategory":{"_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384"},"documentGroupMapping":[{"_key":"ea0d9592c2e2","_ref":"4b9d02fe-9902-49a3-911e-e6b1a5d1b526","_type":"reference"}],"articleType":"Opinion","seoTag":["COPD management","COPD","COPD prevention","COPD diagnosis","Chronic obstructive pulmonary disease"],"taxonomyMapping":[{"_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX"},{"identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8","summary":[{"style":"normal","_key":"8de93ead7686","markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}],"_type":"block"}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z"},{"_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block"}],"identifier":"clinical"},{"identifier":"copd","_id":"topic_copd","_updatedAt":"2021-03-12T23:09:23Z","summary":[{"_key":"002ff14623bd","markDefs":[],"children":[{"_key":"a93ed19c195c","_type":"span","marks":[],"text":"On the "},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"a717dd6a302d"},{"marks":[],"text":"COPD condition center page, resources on the topics of medical news and expert insight into chronic obstructive pulmonary disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on COPD research, treatment, and drug development.","_key":"fa4d38c12dca","_type":"span"}],"_type":"block","style":"normal"}],"parent":{"_ref":"topic_pulmonology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"duatTUEfMZ8Ma3bwePOSKv","_type":"taxonomy","name":"COPD"}]},{"is_visible":true,"_id":"c1e5bc84-6f57-4623-a7a1-12dab80679ac","link":"/view/current-csu-treatment-approach-and-the-role-of-bruton-tyrosine-kinase","url":{"current":"current-csu-treatment-approach-and-the-role-of-bruton-tyrosine-kinase","_type":"slug"},"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"showSocialShare":true,"authorMapping":[{"firstName":"Giselle","displayName":"Giselle Mosnaim, MD, MS ","_createdAt":"2025-02-10T19:42:46Z","_rev":"NT4ETOVf4DRHVmw78jA9gm","_updatedAt":"2025-02-10T19:42:56Z","lastName":"Mosnaim","authorType":"expert","_type":"author","_id":"ad870360-7628-4fea-8d77-e2924564677e","url":{"current":"giselle-mosnaim-md-ms","_type":"slug"}},{"authorType":"expert","_createdAt":"2025-02-10T19:43:23Z","_type":"author","_updatedAt":"2025-02-10T19:43:35Z","url":{"_type":"slug","current":"shyam-joshi-md"},"firstName":"Shyam","lastName":"Joshi","displayName":"Shyam Joshi, MD ","_rev":"wcsTIBGO7X8rh4FCI486MU","_id":"f40abd81-63cc-489d-985a-c1f307da664e"},{"firstName":"Mark","_id":"9a2e024a-a67b-4ee6-a1d8-4f70185cdc1b","_updatedAt":"2024-03-29T13:58:29Z","url":{"current":"mark-lebwohl-md","_type":"slug"},"lastName":"Lebwohl","displayName":"Mark Lebwohl, MD","_createdAt":"2024-03-29T13:58:29Z","_rev":"wktVmwlv7Py7ixALcRNpYO","_type":"author"},{"displayName":"Jason Hawkes, MD, MS","_createdAt":"2023-06-19T15:53:59Z","_rev":"abF4aXKOa4aItNTLQigpeX","_id":"c46cc8d2-54e1-41e4-9719-7aba27a6e9d9","lastName":"Hawkes","_type":"author","_updatedAt":"2023-06-19T15:53:59Z","url":{"current":"jason-hawkes-md-ms","_type":"slug"},"firstName":"Jason"}],"documentGroup":{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference"},"_rev":"XE9vnGgPXscpvWVDkncFWT","published":"2025-02-13T13:05:00.000Z","_updatedAt":"2025-02-13T18:24:30Z","_type":"article","body":[{"videoObject":{"_type":"videoDetails","videoTitle":"Current CSU Treatment Approach and the Role of Bruton Tyrosine Kinase (BTK)","thumbnail":{"asset":{"_ref":"image-2f2ebb5d7addd3f41bc7f5cbb3be74452580b7f5-1920x1080-png","_type":"reference"},"_type":"image"},"videoDuration":"HCP6M45S","videoDescription":"Current CSU Treatment Approach and the Role of Bruton Tyrosine Kinase (BTK)"},"_type":"video","videoID":"6368431792112","disableAutoPlayVideo":false,"source":"brightcove","_key":"84a7647d1457"},{"_key":"59ac43f909fc","markDefs":[],"children":[{"marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"622afb3d553e","_type":"span"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"What mechanisms and targets are currently being utilized or studied for the treatment of CSU?","_key":"fdc73d1b8530"}],"level":1,"_type":"block","style":"normal","_key":"a0acae1b52d6","listItem":"bullet"},{"listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Why are so many patients (more than half) with CSU unable to achieve adequate control with antihistamines alone?","_key":"82d5202ae716"}],"level":1,"_type":"block","style":"normal","_key":"3934bd8b495e"},{"children":[{"_type":"span","marks":[],"text":"What role does BTK play in the pathogenesis of CSU?","_key":"4a50650acc96"}],"level":1,"_type":"block","style":"normal","_key":"f7beb369d58b","listItem":"bullet","markDefs":[]},{"level":1,"_type":"block","style":"normal","_key":"74f1ebd66929","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"BTK signaling is involved in pathways that lead to the degranulation of skin mast cells, which are key pathogenic drivers of CSU.","_key":"e2c007d914b7"}]},{"_key":"ae470a294044","listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"BTK also presents in B cells and basophils, the latter of which activate and degranulate similarly to mast cells.","_key":"2097f34cdebb"}],"level":1,"_type":"block","style":"normal"}],"seoTag":["Chronic Spontaneous Urticaria"],"_createdAt":"2025-02-10T19:50:48Z","documentGroupMapping":[{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference","_key":"a5795c5a2ce2"}],"taxonomyMapping":[{"name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy"},{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive chronic idiopathic urticaria page is a comprehensive resource for clinical news and insights on CIU. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for urticaria, and more.","_key":"d1966bbb3a12"}],"_type":"block","style":"normal","_key":"31027e2639fb"}],"identifier":"chronic-idiopathic-urticaria","_rev":"QX7y4QewgOajo2HeiHq5KN","name":"Chronic Idiopathic Urticaria","_id":"topic_chronic-idiopathic-urticaria","_updatedAt":"2021-08-20T00:22:05Z","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_type":"taxonomy"},{"_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series"},{"_id":"091c96e7-e15c-4b96-8894-79fa589e08d8","summary":[{"_type":"block","style":"normal","_key":"8de93ead7686","markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}]}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange"}],"title":"Current CSU Treatment Approach and the Role of Bruton Tyrosine Kinase ","summary":"Panelists discuss how chronic spontaneous urticaria (CSU) treatment targets multiple pathways through antihistamines, anti-IgE therapy, and BTK inhibitors, with BTK emerging as a key target.","ExcludeFromPubMedXML":false,"articleType":"Opinion","thumbnail":{"asset":{"sha1hash":"895ac0390c516bb6677b19ecd0040c5f858f0796","assetId":"895ac0390c516bb6677b19ecd0040c5f858f0796","mimeType":"image/png","path":"images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","size":2172584,"originalFilename":"TL.00_00_24_13.Still002.png","metadata":{"_type":"sanity.imageMetadata","palette":{"lightMuted":{"foreground":"#000","title":"#fff","population":0.09,"background":"#d6b0b5","_type":"sanity.imagePaletteSwatch"},"vibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34,"background":"#94424d"},"dominant":{"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34},"_type":"sanity.imagePalette","darkMuted":{"population":2.91,"background":"#373d4d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"population":2.73,"background":"#aa8081","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"background":"#edd4d3","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000","population":2.99},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.05,"background":"#261404"}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"height":1080,"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777},"isOpaque":true,"blurHash":"MpIE@SRjS%kCxu~qayX9ofs:jZazoza{RP"},"_createdAt":"2025-02-13T17:04:35Z","_updatedAt":"2025-02-13T17:04:35Z","_id":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","extension":"png","uploadId":"oSnXepOqjz9K6IGvwhhGjyoWZ8FoxhUd","_rev":"XE9vnGgPXscpvWVDknVLRB","_type":"sanity.imageAsset","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png"}}},{"ExcludeFromPubMedXML":false,"_rev":"5MymcCPmeJiqJMv8mYeM1d","showSocialShare":true,"published":"2025-02-13T13:00:00.000Z","articleType":"Opinion","seoTag":["Chronic Spontaneous Urticaria"],"_type":"article","contentCategory":{"_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos"},"title":"Pathophysiology of Chronic Spontaneous Urticaria ","_createdAt":"2025-02-10T19:39:39Z","summary":"Panelists discuss how chronic spontaneous urticaria develops through 2 distinct pathways: autoallergic CSU involving IgE-mediated mast cell activation (type I hypersensitivity) and autoimmune CSU where IgG autoantibodies target FcεRI receptors or IgE itself (type IIb hypersensitivity), both ultimately leading to mast cell degranulation and wheal formation.","taxonomyMapping":[{"summary":[{"style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block"}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z"},{"_rev":"QX7y4QewgOajo2HeiHq5KN","name":"Chronic Idiopathic Urticaria","_id":"topic_chronic-idiopathic-urticaria","_updatedAt":"2021-08-20T00:22:05Z","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_type":"taxonomy","summary":[{"_type":"block","style":"normal","_key":"31027e2639fb","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive chronic idiopathic urticaria page is a comprehensive resource for clinical news and insights on CIU. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for urticaria, and more.","_key":"d1966bbb3a12"}]}],"identifier":"chronic-idiopathic-urticaria"},{"identifier":"video-series","_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z"},{"summary":[{"_key":"8de93ead7686","markDefs":[],"children":[{"_type":"span","marks":[],"text":"HCPLive® Peer Exchange panel discussions feature authoritative insights, opinions, and perspectives on important issues facing today's care professionals.","_key":"45fb07f11b0f"}],"_type":"block","style":"normal"}],"_createdAt":"2020-06-16T21:08:54Z","_rev":"NdnrpkkhKMOTty4L8Ea56i","_type":"taxonomy","name":"Peer Exchange","_updatedAt":"2021-07-12T14:46:37Z","identifier":"peer-exchange","_id":"091c96e7-e15c-4b96-8894-79fa589e08d8"}],"link":"/view/pathophysiology-of-chronic-spontaneous-urticaria","url":{"current":"pathophysiology-of-chronic-spontaneous-urticaria","_type":"slug"},"authorMapping":[{"firstName":"Giselle","displayName":"Giselle Mosnaim, MD, MS ","_createdAt":"2025-02-10T19:42:46Z","_rev":"NT4ETOVf4DRHVmw78jA9gm","_updatedAt":"2025-02-10T19:42:56Z","lastName":"Mosnaim","authorType":"expert","_type":"author","_id":"ad870360-7628-4fea-8d77-e2924564677e","url":{"current":"giselle-mosnaim-md-ms","_type":"slug"}},{"authorType":"expert","_createdAt":"2025-02-10T19:43:23Z","_type":"author","_updatedAt":"2025-02-10T19:43:35Z","url":{"_type":"slug","current":"shyam-joshi-md"},"firstName":"Shyam","lastName":"Joshi","displayName":"Shyam Joshi, MD ","_rev":"wcsTIBGO7X8rh4FCI486MU","_id":"f40abd81-63cc-489d-985a-c1f307da664e"},{"lastName":"Lebwohl","displayName":"Mark Lebwohl, MD","_createdAt":"2024-03-29T13:58:29Z","_rev":"wktVmwlv7Py7ixALcRNpYO","_type":"author","firstName":"Mark","_id":"9a2e024a-a67b-4ee6-a1d8-4f70185cdc1b","_updatedAt":"2024-03-29T13:58:29Z","url":{"current":"mark-lebwohl-md","_type":"slug"}},{"_rev":"abF4aXKOa4aItNTLQigpeX","_id":"c46cc8d2-54e1-41e4-9719-7aba27a6e9d9","lastName":"Hawkes","_type":"author","_updatedAt":"2023-06-19T15:53:59Z","url":{"current":"jason-hawkes-md-ms","_type":"slug"},"firstName":"Jason","displayName":"Jason Hawkes, MD, MS","_createdAt":"2023-06-19T15:53:59Z"}],"_id":"e2204837-037b-4346-b134-7ea8cc68b4fd","documentGroupMapping":[{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference","_key":"a5795c5a2ce2"}],"_updatedAt":"2025-02-13T17:07:23Z","is_visible":true,"documentGroup":{"_ref":"cf7cfd00-f010-406d-b386-e09e6fbcfb6b","_type":"reference"},"body":[{"disableAutoPlayVideo":false,"source":"brightcove","_key":"84a7647d1457","videoObject":{"videoDuration":"HCP5M50S","videoDescription":"Pathophysiology of Chronic Spontaneous Urticaria","_type":"videoDetails","videoTitle":"Pathophysiology of Chronic Spontaneous Urticaria","thumbnail":{"_type":"image","asset":{"_ref":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","_type":"reference"}}},"_type":"video","videoID":"6368429440112"},{"markDefs":[],"children":[{"_type":"span","marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"622afb3d553e"}],"_type":"block","style":"normal","_key":"59ac43f909fc"},{"listItem":"bullet","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Describe the pathogenesis of chronic spontaneous urticaria (CSU), including the IgE (autoallergic; type I) and IgG (autoimmune; type IIb) CSU subtypes.","_key":"fdc73d1b8530"}],"level":1,"_type":"block","style":"normal","_key":"a0acae1b52d6"}],"thumbnail":{"asset":{"_type":"sanity.imageAsset","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","sha1hash":"895ac0390c516bb6677b19ecd0040c5f858f0796","assetId":"895ac0390c516bb6677b19ecd0040c5f858f0796","mimeType":"image/png","path":"images/0vv8moc6/hcplive/895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080.png","size":2172584,"originalFilename":"TL.00_00_24_13.Still002.png","metadata":{"dimensions":{"height":1080,"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777},"isOpaque":true,"blurHash":"MpIE@SRjS%kCxu~qayX9ofs:jZazoza{RP","_type":"sanity.imageMetadata","palette":{"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.34,"background":"#94424d"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":2.91,"background":"#373d4d","_type":"sanity.imagePaletteSwatch"},"muted":{"population":2.73,"background":"#aa8081","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"title":"#000","population":2.99,"background":"#edd4d3","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"foreground":"#fff","title":"#fff","population":0.05,"background":"#261404","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"background":"#d6b0b5","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.09},"vibrant":{"title":"#fff","population":3.34,"background":"#94424d","_type":"sanity.imagePaletteSwatch","foreground":"#fff"}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAALCAYAAAB/Ca1DAAAACXBIWXMAAAPoAAAD6AG1e1JrAAAAFHRFWHRDcmVhdG9yAFByZW1pZXJlIFByb2l7TwQAAAMSSURBVHicPcX9U5MFAMDx5x/outMrso672HgxsOyEOGQaC5WN8brNQl6CEhezvC5fsCAROUVCyDyTLhDkIJm1MQZMNto7e8bmbmMvSARczLqyu7r+h293dNcPn/sIkc2nRDefEtv6g8jPv+J+FGPaamNhbobHD+dJzc7yxGIhZVtgOxpi/acYwWAAn1ckFt9gLfUXySd/k9j5H4RAcpvg6jbhtRTBxAYPnT4MJjNWk5HY2DjrA7dYv3mbtZFREgtWVpZ9BPw+3F6RUOQxsY3fiG7+vmNl60+ExUAcZzDOUngVp8vP/bF7jAzdwWKYImyYIv7tMPHhEWITE0QsZsI/2vC5nNgdbtz+EOLKGsHEFuHkL0RXUwjmxSXmnCI2p8gPkwaGei7z1eUOpu6NsOyyk1hykfC7SYoeEgEP0YAHj3MRi3ka64wFhzeA51ESMZRkObSKYLJ5Mdu9jBvMXO2+Qoe+lXZdC71XLjE/ZyIS9hNbWSYeXWYlIhIQ3ZjNRu4O3WHs9tdMPZhm1iFi94Z3CEarm8lpK591X0Oj0dCoqeWEupp3jmsZHOjD5bASDLh2iH4HRtMDunp6OX+2g87zl7jw6VUGv5nAuOBmxuFHGP/ewpdDo9Q3t6IoU9DW0oKuuRmVshy9vo3vJkex22ZYtFmwzpvoHxhEW6+j6d2P+VB3EfVxHfqzXQxPGrk/s4DQ3XeTM+c6UFVpOPF2Hb2dn3O9s5PGugZq1VraL7bT39/HjRtf0Hv9Gqf0ZzhWUUdj00ecPnWByuom1PWttHf10tN/C0FZoeato+UUFb+JUqGi7b2TnD7ZSrWqClnxYUpLj1CuVO1QKsopKSlFJpOjKKukpkrL0WOVyI8oKSuvQVlRi5CVkcFeqYTcTAn7c7IofDWXg/tzKczLpmCvlPwcCfnZGf97I0dC4StSivKyKS3Kp0ZZRrVKiVxWzIF9eQjpu54h8/lnyX1pF6+l7+b19N0UvPwcB6VpHMraw+GsPRRL0yiW/EcmfYFDmWnIs19EW1LAJ+83cO6DFhqqFMgP7ONfLbQ24N2oAaIAAAAASUVORK5CYII="},"_createdAt":"2025-02-13T17:04:35Z","_updatedAt":"2025-02-13T17:04:35Z","_id":"image-895ac0390c516bb6677b19ecd0040c5f858f0796-1920x1080-png","extension":"png","uploadId":"oSnXepOqjz9K6IGvwhhGjyoWZ8FoxhUd","_rev":"XE9vnGgPXscpvWVDknVLRB"}}},{"articleType":"Opinion","is_visible":true,"url":{"_type":"slug","current":"switching-or-staying-within-the-treatment-class"},"thumbnail":{"asset":{"metadata":{"palette":{"muted":{"foreground":"#000","title":"#fff","population":0,"background":"#b4946c","_type":"sanity.imagePaletteSwatch"},"lightVibrant":{"background":"#ecb9a8","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.26},"darkVibrant":{"population":0.02,"background":"#810418","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"population":0.03,"background":"#bacddc","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000"},"vibrant":{"title":"#fff","population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"population":7.73,"background":"#8f191d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"background":"#3b2925","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":4.7}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1920,"aspectRatio":1.7777777777777777,"height":1080},"isOpaque":false,"blurHash":"MnINs}X9RPWURk~qo0WBaeWC-qRjkCjZoe","_type":"sanity.imageMetadata"},"uploadId":"tRZtfAPN89t4PeZm1FfsoaO1PgPSPAwP","path":"images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png","size":1228069,"assetId":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","_createdAt":"2024-12-24T14:24:15Z","mimeType":"image/png","sha1hash":"cc35d0a5d6bdfc82208e68d23b2793b2fb56117f","_id":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","originalFilename":"Marketing Image - 2024-12-24T091913.556.png","extension":"png","_rev":"5K24o7vC94LP4crFJHTRn6","_type":"sanity.imageAsset","_updatedAt":"2024-12-24T14:24:15Z","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080.png"}},"_rev":"xQ59ksnL97kRasvNOZo1Gm","title":"Switching or Staying Within the Treatment Class","seoTag":["Atopic dermatitis"],"ExcludeFromPubMedXML":false,"_createdAt":"2025-01-28T16:54:17Z","body":[{"source":"brightcove","_key":"791c39ddaa4a","videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-cc35d0a5d6bdfc82208e68d23b2793b2fb56117f-1920x1080-png","_type":"reference"}},"videoDuration":"HCP2m39s","videoDescription":"Switching or Staying Within the Treatment Class","_type":"videoDetails","videoTitle":"Switching or Staying Within the Treatment Class"},"_type":"video","videoID":"6367089646112","disableAutoPlayVideo":false},{"children":[{"_type":"span","marks":["strong","em"],"text":"Video content above is prompted by the following:","_key":"ae1f355b42a1"}],"_type":"block","style":"normal","_key":"c10a68b50e4d","markDefs":[]},{"_key":"9ac246685bec","listItem":"bullet","markDefs":[],"children":[{"_key":"d718caf39e9b","_type":"span","marks":[],"text":"Can you talk about when we should consider switching to another biologic or when to go with a different mechanism of action?"}],"level":1,"_type":"block","style":"normal"}],"_updatedAt":"2025-02-18T15:52:18Z","link":"/view/switching-or-staying-within-the-treatment-class","documentGroup":{"_ref":"7ca9367a-b7bb-4fcc-8d06-bcaf20ab44c0","_type":"reference"},"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"_id":"f664d3c5-7195-48d4-a812-36589e6793c6","authorMapping":[{"firstName":"Linda","displayName":"Linda Stein Gold, MD","_createdAt":"2022-04-27T14:18:21Z","_rev":"IMgnVSbg9NVYxCJ63gNftZ","_id":"76cd476e-ca5b-4ba8-8582-643021fd1ae4","lastName":"Stein Gold","_type":"author","_updatedAt":"2022-04-27T14:18:21Z","url":{"current":"linda-stein-gold-md","_type":"slug"}},{"lastName":"Golant","displayName":"Alexandra K. Golant, MD","_createdAt":"2022-04-27T14:18:50Z","_rev":"h2V9BXWDd08V4aY6nLN0GR","_id":"4cf3baed-afa1-4a0b-9ee5-2a9267c19e71","_type":"author","_updatedAt":"2022-04-27T14:18:50Z","url":{"current":"alexandra-k-golant-md","_type":"slug"},"firstName":"Alexandra"},{"_updatedAt":"2021-09-10T14:33:14Z","url":{"_type":"slug","current":"peter-lio-md"},"lastName":"Lio","displayName":"Peter Lio, MD ","_rev":"RNMve0hiapSaZS4aIAOSS6","_type":"author","firstName":"Peter","_createdAt":"2021-09-10T14:33:14Z","company":"Northwestern University Feinberg School of Medicine","_id":"d9e83aaa-e52e-4b4c-8251-da434c87ec17"},{"firstName":"Jennifer","lastName":"Soung","displayName":"Jennifer Soung, MD","_rev":"1Z6vF4pxH4OlF0724m7fJP","_type":"author","_id":"0d5cce5d-d3c8-4eac-adf6-80e0d28e8a75","_updatedAt":"2023-11-10T14:46:58Z","url":{"current":"jennifer-soung-md","_type":"slug"},"_createdAt":"2023-11-10T14:46:58Z"}],"taxonomyMapping":[{"summary":[{"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"text":"The ","_key":"eee871ba2638","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"17c44b92092c"},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}]}],"identifier":"clinical","_createdAt":"2020-05-20T18:05:03Z","_type":"taxonomy","name":"Clinical","isMainTopic":true,"_rev":"jFlyVyB0S45zgvAzVefOS0","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z"},{"_createdAt":"2020-10-14T05:36:04Z","_rev":"5Yey6I4rZyWcODD45dIdoX","_type":"taxonomy","name":"Video Series","_id":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_updatedAt":"2020-10-14T05:36:04Z","identifier":"video-series"}],"documentGroupMapping":[{"_ref":"7ca9367a-b7bb-4fcc-8d06-bcaf20ab44c0","_type":"reference","_key":"1a893c3005a0"}],"published":"2025-02-11T13:05:00.000Z","summary":"Panelists discuss when to consider switching to another biologic or exploring a different mechanism of action in atopic dermatitis treatment, focusing on factors like inadequate response, adverse effects, or the need for more targeted therapy to optimize patient outcomes.","_type":"article","showSocialShare":true}],"videoNonSeriesData":[{"_createdAt":"2025-02-20T16:18:27Z","ExcludeFromPubMedXML":false,"body":[{"disableAutoPlayVideo":false,"source":"brightcove","_key":"d2bcc9c4ced0","videoObject":{"videoDescription":"Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD","_type":"videoDetails","videoTitle":"Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD","thumbnail":{"_type":"image","asset":{"_ref":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","_type":"reference"}},"videoDuration":"3M01S"},"_type":"video","videoID":"6369101018112"},{"markDefs":[{"href":"https://www.hcplive.com/clinical/amd","_key":"36edcc532114","blank":true,"_type":"link"}],"children":[{"text":"Aflibercept 8 mg (EYLEA HD) achieved positive results at 3 years among patients with ","_key":"dee93b4c5b47","_type":"span","marks":[]},{"_key":"1088df65d962","_type":"span","marks":["36edcc532114"],"text":"neovascular (wet) age-related macular degeneration (nAMD)"},{"_type":"span","marks":[],"text":" in an extension study of the Phase 3 PULSAR trial.","_key":"331335025e27"},{"_type":"span","marks":["sup"],"text":"1","_key":"8a2e74810b06"}],"_type":"block","style":"normal","_key":"28b523a16f93"},{"_key":"8f8d56297498","markDefs":[],"children":[{"text":"Announced by Regeneron Pharmaceuticals on February 8, 2025, these findings, presented at Angiogenesis, Exudation, and Degeneration 2025, revealed most patients treated with aflibercept 8 mg continued to experience improvements in vision and anatomy, with extended dosing intervals.","_key":"cc5ac4b1ecd5","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"36122872d691","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“In the PULSAR extension, a large percentage of patients can be extended out to 4 months or even longer, with good disease control,” W. Lloyd Clark, MD, Palmetto Retinal Center, and assistant clinical professor of ophthalmology at the University of South Carolina School of Medicine told ","_key":"6f23ec7139ed"},{"marks":["em"],"text":"HCPLive. ","_key":"299f4d15dd54","_type":"span"},{"_key":"3d57bf4ee229","_type":"span","marks":[],"text":"“This really does represent the next incremental improvement in the chronic treatment of patients with wet AMD.”"}]},{"style":"normal","_key":"63d866b6910f","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/clinical/fda-news","_key":"857a5a751878"}],"children":[{"_type":"span","marks":[],"text":"The ","_key":"8ecf0987fc61"},{"_type":"span","marks":["857a5a751878"],"text":"US Food and Drug Administration (FDA)","_key":"0ea6931b0736"},{"_key":"12f230c33920","_type":"span","marks":[],"text":" approved aflibercept 8 mg for wet age-related macular degeneration (AMD), diabetic macular edema (DME), and diabetic retinopathy in August 2023."},{"_type":"span","marks":["sup"],"text":"2","_key":"6e8ddd2bfe95"},{"_key":"868c993b9e44","_type":"span","marks":[],"text":" Wet AMD occurs after the growth of abnormal blood vessels leak fluid under the macula, with nearly 1.4 million people in the US at risk of vision loss from AMD."},{"text":"3","_key":"e5e652e26e9a","_type":"span","marks":["sup"]}],"_type":"block"},{"_type":"block","style":"normal","_key":"5c68acfe8531","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The PULSAR trial was a double-masked, active-controlled pivotal trial in patients with wet AMD, reporting 88% of all patients on aflibercept 8 mg maintaining ≥3-month dosing intervals at the end of 2 years. After its completion, an optional extension study began at Week 96, with all participants receiving aflibercept 8 mg across Week 156. Dosing intervals in the extension study could be reduced or extended by 2-week increments based on certain criteria, with a minimum interval of every 2 months and a maximum of every 6 months.","_key":"67d2fd97d02d"},{"_type":"span","marks":["sup"],"text":"1","_key":"c311f0815811"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Among those who completed the full 3 years of treatment (n = 375), nearly 60% had a last assigned dosing interval of ≥4 months. Approximately 40% and 24% had a final assigned dosing interval of ≥5 months and 6 months at the end of 3 years. Visual and anatomic improvements, including reductions in retinal thickness, were sustained through year 3 in the extension.","_key":"e586283b66dc"}],"_type":"block","style":"normal","_key":"394328e28018"},{"children":[{"_type":"span","marks":[],"text":"Those in the comparator arm were treated with aflibercept (EYLEA) as a fixed 2-month dosing regimen for 96 weeks and could switch to a 3-month dosing interval with aflibercept 8 mg until Week 156. Among those who completed the extension (n = 186) after switching, these data showed maintenance of vision and anatomic improvements, with 79% and 43% on an assigned dosing interval of ≥3 and ≥4 months, respectively.","_key":"6efd6cea447c"}],"_type":"block","style":"normal","_key":"3e225351f525","markDefs":[]},{"_type":"block","style":"normal","_key":"c0617efcd790","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The safety of aflibercept 8 mg was similar to aflibercept across 3 years and remained generally consistent with the known profile from pivotal trials. Ocular treatment-emergent adverse events (TEAEs) were reported in ≥4% of all patients, including cataracts, retinal hemorrhage, reduction of visual acuity, vitreous floaters, and increase of intraocular pressure. The rate of intraocular inflammation was 2.4% for the patients who switched from aflibercept to aflibercept, and 1.9% for those randomized at baseline.","_key":"b54cba0a462a"}]},{"children":[{"marks":[],"text":"“These patients typically stay on treatment for life and I’ve got patients in my clinic that have been on injections pushing 20 years,” Clark told ","_key":"df1ae151e70e","_type":"span"},{"_type":"span","marks":["em"],"text":"HCPLive","_key":"18129c2ec635"},{"_type":"span","marks":[],"text":". “If we can reduce the number of treatment visits for these patients, it will significantly increase their quality of life. These patients with wet AMD are typically more compliant and so they welcome the idea of coming less frequently.”","_key":"75c3e531ee5d"}],"_type":"block","style":"normal","_key":"37f4609fa9cf","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Relevant disclosures for Clark include Amgen, Genentech/Roche, Regeneron, and others.","_key":"88fb7118ca66"}],"_type":"block","style":"normal","_key":"07a5e7b04381"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"References","_key":"5eab0c173ebf"}],"_type":"block","style":"normal","_key":"6082d6567a81"},{"_key":"876ab8de5341","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Three-year results for Eylea HD® (aflibercept) injection 8 mg in patients with wet age-related macular degeneration demonstrate continued durable vision gains and anatomic improvements with extended dosing intervals. Regeneron Pharmaceuticals Inc. February 8, 2025. Accessed February 20, 2025. https://newsroom.regeneron.com/news-releases/news-release-details/three-year-results-eylea-hdr-aflibercept-injection-8-mg-patients.","_key":"4591a6ad9ef1"}],"level":1,"_type":"block","style":"h6"},{"children":[{"_key":"1891a4a46acd","_type":"span","marks":[],"text":"Campbell P. Aflibercept 8 mg (eylea HD) approved by FDA for wet AMD, DME, and Diabetic retinopathy. HCP Live. August 23, 2023. Accessed February 19, 2025. https://www.hcplive.com/view/aflibercept-8mg-eylea-hd-approved-by-fda-for-wamd-dme-and-diabetic-retinopathy."}],"level":1,"_type":"block","style":"h6","_key":"cb7756022567","listItem":"number","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"Ruia S, Kaufman EJ. Macular Degeneration. [Updated 2023 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK560778/","_key":"e65e1a8f6813"}],"level":1,"_type":"block","style":"h6","_key":"626ac4514215","listItem":"number","markDefs":[]}],"published":"2025-02-20T16:15:12.251Z","title":"Aflibercept 8 mg Shows Durability at 3 Years in Wet AMD with W. Lloyd Clark, MD","articleType":"News","summary":"Clark describes visual and anatomic improvements with aflibercept 8 mg in the PULSAR extension study, with most patients achieving extended dosing regimens.","_type":"article","thumbnail":{"asset":{"extension":"jpg","_id":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","originalFilename":"W. Lloyd Clark, MD.jpeg","metadata":{"isOpaque":true,"blurHash":"eIG8yO?H5kNG^j~VRPpIbIIA9FRjRQazoeENofrWs:x^XSay%2ayM{","_type":"sanity.imageMetadata","palette":{"darkVibrant":{"background":"#0b1625","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.02},"lightMuted":{"population":7.65,"background":"#c2a499","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"background":"#3a74c4","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0},"dominant":{"population":7.65,"background":"#c2a499","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.59,"background":"#604234"},"muted":{"foreground":"#fff","title":"#fff","population":1.79,"background":"#a3715e","_type":"sanity.imagePaletteSwatch"},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":4.83,"background":"#e0a491"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":300,"aspectRatio":1,"height":300}},"_rev":"BpNdyQCG1dl0w7WYXlIgvj","sha1hash":"6d87f07338586a48041ba67e900189789aa40d8a","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg","_createdAt":"2023-11-05T17:22:08Z","_updatedAt":"2023-11-05T17:22:08Z","_type":"sanity.imageAsset","mimeType":"image/jpeg","assetId":"6d87f07338586a48041ba67e900189789aa40d8a","uploadId":"TTF2WdHDaiIZTf2ZMQ6iguHLdrxvluOA","path":"images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg","size":15600}},"url":{"current":"aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md","_type":"slug"},"is_visible":true,"taxonomyMapping":[{"_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy"},{"_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"_type":"taxonomy","identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z"},{"_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy","name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z"},{"_rev":"L7yG3IvIye3EpJsuLI6lj5","name":"Ophthalmology","_id":"topic_ophthalmology","summary":[{"style":"normal","_key":"7f7e7f1fc48d","markDefs":[],"children":[{"marks":[],"text":"On the ","_key":"b608c592ab02","_type":"span"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"cdba8d4004fe"},{"_type":"span","marks":[],"text":"Ophthalmology page, resources on the topics of medical news and expert insight into ophthalmic disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on eye disease research, treatment, and drug development.","_key":"34b8afe797af"}],"_type":"block"}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"cmeType":"per","_type":"taxonomy","_updatedAt":"2023-03-30T18:45:07Z","identifier":"ophthalmology","perKeywordMapping":["Ophthalmology","Optometry"],"pixelTrackingCode":{"_ref":"21fa5627-6528-45fb-938c-762770c2a663","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z"},{"_updatedAt":"2022-04-15T16:31:40Z","summary":[{"markDefs":[],"children":[{"marks":[],"text":"The ","_key":"d83294976cb8","_type":"span"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"c6383aa22916"},{"_type":"span","marks":[],"text":"age-related macular degeneration condition center page is a comprehensive resource for clinical news and insights on retina disease. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for patients with AMD.","_key":"4c41646dd966"}],"_type":"block","style":"normal","_key":"bbbdae203daa"}],"identifier":"amd","parent":{"_ref":"topic_ophthalmology","_type":"reference"},"_id":"8d2ddf0a-2685-4e62-b599-c3fd9c9f1ad8","_createdAt":"2022-04-15T16:30:27Z","_rev":"k74QslJWVHh8BDW1v1JjRa","_type":"taxonomy","name":"Age-Related Macular Degeneration"}],"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"link":"/view/aflibercept-8-mg-shows-durability-at-3-years-in-wet-amd-with-w-lloyd-clark-md","_updatedAt":"2025-02-20T16:18:27Z","authorMapping":[{"url":{"current":"w-lloyd-clark-md","_type":"slug"},"displayName":"W. Lloyd Clark, MD","_createdAt":"2021-11-08T20:30:12Z","_rev":"WTa1tCSmB5FyFHeNdE1Kzw","_type":"author","_id":"224f64fc-5a87-46c6-b638-16571568feac","_updatedAt":"2021-11-08T20:30:12Z"},{"_updatedAt":"2025-01-13T19:54:59Z","url":{"current":"connor-iapoce","_type":"slug"},"authorType":"author","displayName":"Connor Iapoce","_createdAt":"2021-04-06T14:07:28Z","_rev":"lMqTJ7iiwxFTeHbLVhHzE4","_type":"author","firstName":"Connor","lastName":"Iapoce","_id":"976f58a6-1439-429f-a1ac-5b1bc00855ef","biography":[{"_type":"block","style":"normal","_key":"599533f3f0aa","markDefs":[],"children":[{"text":"Connor Iapoce is the assistant managing editor for ","_key":"f2f59465653b","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive, ","_key":"c19214c63e58"},{"_type":"span","marks":[],"text":"after","_key":"d7fed3c60b95"},{"_key":"0aefa727bc2b","_type":"span","marks":["em"],"text":" "},{"_type":"span","marks":[],"text":"joining the MJH Life Sciences team in April 2021. He graduated from The College of New Jersey with a degree in Journalism and Professional Writing. He enjoys listening to records, going to the movies, and playing with his cat, Squish. You can reach him at ","_key":"64fc9d50c821"},{"_type":"span","marks":["underline"],"text":"ciapoce@mjhlifesciences.com","_key":"303c2d464c84"},{"_type":"span","marks":[],"text":".","_key":"3e46e883cc67"}]}]}],"_id":"81ad9042-7688-45a8-8e40-d82cf285e725","_rev":"o0lY0lMSCBNEoNDZvetSO4"},{"thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp","_updatedAt":"2025-02-20T00:11:57Z","extension":"webp","path":"images/0vv8moc6/hcplive/1e39f2bffa24ec93339878a0450fab82714d105f-320x320.webp","_createdAt":"2025-02-20T00:11:57Z","_id":"image-1e39f2bffa24ec93339878a0450fab82714d105f-320x320-webp","metadata":{"blurHash":"e5GHuI,m00%#^N00tT-;8_Nf00-O}[tT-nVCE6-;r;EQ0jR$~A-;9@","_type":"sanity.imageMetadata","palette":{"dominant":{"title":"#fff","population":12.09,"background":"#614718","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":9.01,"background":"#725a34","_type":"sanity.imagePaletteSwatch"},"muted":{"population":10.83,"background":"#a38372","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"foreground":"#000","title":"#fff","population":0.05,"background":"#e4b6ae","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"background":"#614718","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":12.09},"lightMuted":{"title":"#fff","population":10.27,"background":"#c4a293","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"foreground":"#fff","title":"#fff","population":0,"background":"#bc6474","_type":"sanity.imagePaletteSwatch"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":320,"aspectRatio":1,"height":320},"isOpaque":true},"_type":"sanity.imageAsset","assetId":"1e39f2bffa24ec93339878a0450fab82714d105f","originalFilename":"chalmers.webp","uploadId":"wXbNK6mZhvncEquaHtNIRqxhS6u5tT7E","_rev":"cID2mV6fSdv64jOtmNsNRV","sha1hash":"1e39f2bffa24ec93339878a0450fab82714d105f","size":9822,"mimeType":"image/webp"}},"authorMapping":[{"firstName":"Victoria","lastName":"Johnson","_rev":"R5Nwo2wgBUbo1xFZSWuqlM","_id":"d4c32d40-a161-4f01-8151-702eff7a6e75","url":{"current":"victoria-johnson","_type":"slug"},"displayName":"Victoria Johnson","_createdAt":"2020-12-10T20:09:41Z","_type":"author","biography":[{"_type":"block","style":"normal","_key":"bf207805c002","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Victoria Johnson joined the MJH Life Sciences in 2020 and has written for NeurologyLive, CGTLive, and now HCPLive. You can reach her at vjohnson@mjhlifesciences.com","_key":"69caae9c35c7"}]}],"_updatedAt":"2024-09-16T22:30:31Z"},{"firstName":"James","authorType":"expert","displayName":"James Chalmers, MBChB, PhD","_rev":"Fd1jDX9jbPHQLM4ybp1jkq","_id":"3a7b60a7-e557-4ce1-95f5-1fa93c43f5db","_updatedAt":"2025-02-20T00:07:24Z","url":{"current":"james-chalmers-mbchb-phd","_type":"slug"},"lastName":"Chalmers, MBChB, PhD","_createdAt":"2025-02-20T00:07:24Z","_type":"author"}],"taxonomyMapping":[{"_type":"taxonomy","name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn"},{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z"},{"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"perKeywordMapping":["Pulmonology","Critical Care","Lung Cancer"],"cmeType":"per","_rev":"SptJyyJZlDXHKuYmZmgZ51","name":"Pulmonology","summary":[{"children":[{"text":"The ","_key":"9046723a5453","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"3ed08285fbac"},{"_type":"span","marks":[],"text":"Infectious Disease condition center page is a comprehensive resource for clinical news and insights on respiratory health. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for asthma, COPD, interstitial lung disease, COVID-19, and more.","_key":"e99036a8f5e0"}],"_type":"block","style":"normal","_key":"8b99413ae62f","markDefs":[]}],"identifier":"pulmonology","_createdAt":"2020-05-20T18:09:49Z","_type":"taxonomy","_id":"topic_pulmonology","_updatedAt":"2023-03-30T18:47:06Z"},{"_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"_type":"taxonomy","identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical"}],"is_visible":true,"ExcludeFromPubMedXML":false,"body":[{"caption":"Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD","videoID":"6369068547112","disableAutoPlayVideo":false,"source":"brightcove","_key":"c5653536def3","videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-ca91fe58cae81ff89f48bbaafcec833ee5ca6d7f-1280x720-jpg","_type":"reference"}},"videoDuration":"PT8M28S","videoDescription":"Chalmers discussed how brensocatib’s potential approval may transform the currently empty treatment landscape for bronchiectasis.","_type":"videoDetails","videoTitle":"Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD"},"_type":"video"},{"children":[{"text":"The FDA has accepted and granted priority review to Insmed’s New Drug Application (NDA) for brensocatib, a potential first treatment for patients with non-cystic fibrosis bronchiectasis. The therapy has a Prescription Drug User Fee Act (PDUFA) of August 12, 2025.","_key":"c2db8aa423de","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"dbfe5c5d9ff4","markDefs":[]},{"_key":"9ab26c2bdbac","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The NDA submission was based on data from the landmark Phase 3 ASPEN study, which met its primary endpoint of clinically and statistically significantly reducing the annualized rate of pulmonary exacerbations compared with placebo over 52 weeks in both its 10 and 25 mg dosages. The study assessed brensocatib 10 mg, brensocatib 25 mg, or placebo once daily for 52 weeks, followed by 4 weeks off treatment, in adults and adolescents.","_key":"fafc4e2dd882"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"HCPLive","_key":"deee5b76861f"},{"_type":"span","marks":[],"text":"® spoke with James Chalmers, MBChB, PhD, Professor, Asthma and Lung UK Chair of Respiratory Research, MBChB, PhD, FRCPE, FERS, Clinical Professor (Teaching and Research) of Respiratory Research, Respiratory Medicine and Gastroenterology, University of Dundee, United Kingdom, who served as a primary investigator on the ASPEN study, to learn more about bronchiectasis and its unmet needs in the field. He discussed brensocatib and how it may benefit patients with bronchiectasis as the potential first treatment to be approved for the condition.","_key":"c94463c9f5ff"}],"_type":"block","style":"normal","_key":"6d1ef30b20f0"},{"children":[{"marks":[],"text":"“[Bronchiectasis has] been neglected, a bit of a Cinderella condition. In 2011 the European Respiratory Society… described bronchiectasis as the most neglected disease in respiratory medicine, because there's so many patients, but nobody was really doing research into it, and nobody, nobody was doing any clinical trials. And so, it's really exciting that that's now changing, because our patients really need it to change. And this [potential] first licensed therapy is a step towards addressing that major burden,” Chalmers told ","_key":"82fc2e4bb0ec","_type":"span"},{"_type":"span","marks":["em"],"text":"HCPLive.","_key":"313f8999b6e2"}],"_type":"block","style":"normal","_key":"578505416964","markDefs":[]},{"_type":"block","style":"normal","_key":"cd16880deab2","markDefs":[],"children":[{"text":"Chalmers shared his excitement for the potential FDA approval of brensocatib and also discussed some priorities in bronchiectasis research and care that will follow after getting a first treatment.","_key":"fbf5fcba0f7e","_type":"span","marks":[]}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"REFERENCE","_key":"5837ee1b5f80"}],"_type":"block","style":"h6","_key":"2846afe34a69"},{"markDefs":[],"children":[{"marks":[],"text":"FDA Grants Priority Review to Insmed's Brensocatib for Treatment of Bronchiectasis with PDUFA Target Action Date Set for August 12, 2025. News release. Insmed. February 6, 2025. https://www.prnewswire.com/news-releases/fda-grants-priority-review-to-insmeds-brensocatib-for-treatment-of-bronchiectasis-with-pdufa-target-action-date-set-for-august-12-2025-302369466.html","_key":"67490a5b5057","_type":"span"}],"_type":"block","style":"h6","_key":"4e6b8d6e7623"}],"title":"Investigating Brensocatib, Potential First Treatment for Bronchiectasis, with James Chalmers, MBChB, PhD","contentCategory":{"_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z"},"summary":"Chalmers discussed how brensocatib’s potential approval may transform the currently empty treatment landscape for bronchiectasis.","published":"2025-02-20T00:06:54.912Z","_type":"article","url":{"current":"investigating-brensocatib-first-treatment-bronchiectasis-chalmers","_type":"slug"},"_id":"04775208-b774-4a8e-af2b-7681676b6e44","articleType":"Commentary","_createdAt":"2025-02-20T00:12:02Z","_updatedAt":"2025-02-20T00:12:02Z","_rev":"Fd1jDX9jbPHQLM4ybp2ciM","link":"/view/investigating-brensocatib-first-treatment-bronchiectasis-chalmers"},{"authorMapping":[{"displayName":"W. Lloyd Clark, MD","_createdAt":"2021-11-08T20:30:12Z","_rev":"WTa1tCSmB5FyFHeNdE1Kzw","_type":"author","_id":"224f64fc-5a87-46c6-b638-16571568feac","_updatedAt":"2021-11-08T20:30:12Z","url":{"current":"w-lloyd-clark-md","_type":"slug"}},{"_id":"976f58a6-1439-429f-a1ac-5b1bc00855ef","biography":[{"markDefs":[],"children":[{"text":"Connor Iapoce is the assistant managing editor for ","_key":"f2f59465653b","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive, ","_key":"c19214c63e58"},{"_type":"span","marks":[],"text":"after","_key":"d7fed3c60b95"},{"_key":"0aefa727bc2b","_type":"span","marks":["em"],"text":" "},{"_type":"span","marks":[],"text":"joining the MJH Life Sciences team in April 2021. He graduated from The College of New Jersey with a degree in Journalism and Professional Writing. He enjoys listening to records, going to the movies, and playing with his cat, Squish. You can reach him at ","_key":"64fc9d50c821"},{"_type":"span","marks":["underline"],"text":"ciapoce@mjhlifesciences.com","_key":"303c2d464c84"},{"_type":"span","marks":[],"text":".","_key":"3e46e883cc67"}],"_type":"block","style":"normal","_key":"599533f3f0aa"}],"_updatedAt":"2025-01-13T19:54:59Z","url":{"current":"connor-iapoce","_type":"slug"},"authorType":"author","displayName":"Connor Iapoce","_createdAt":"2021-04-06T14:07:28Z","_rev":"lMqTJ7iiwxFTeHbLVhHzE4","_type":"author","firstName":"Connor","lastName":"Iapoce"}],"published":"2025-02-19T23:00:36.096Z","body":[{"videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","_type":"reference"}},"videoDuration":"2M58S","videoDescription":"Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD","_type":"videoDetails","videoTitle":"Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD"},"_type":"video","videoID":"6369064320112","disableAutoPlayVideo":false,"source":"brightcove","_key":"a7a061354b65"},{"_type":"block","style":"normal","_key":"8627f66f4d4d","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/clinical/ophthalmology","_key":"04591ee8bc0c"}],"children":[{"_type":"span","marks":[],"text":"Positive results from the Phase 3 QUASAR trial demonstrate the noninferiority of aflibercept 8 mg (EYLEA HD) administered every 8 weeks to aflibercept 2 mg (EYLEA) dosed every 4 weeks for treating ","_key":"d02acb79330c"},{"marks":["04591ee8bc0c"],"text":"macular edema secondary to retinal vein occlusion (RVO)","_key":"838957e08606","_type":"span"},{"marks":[],"text":".","_key":"a1abd91015f4","_type":"span"},{"_type":"span","marks":["sup"],"text":"1","_key":"e9c3e0c1b0fc"}]},{"_key":"660a2dd0c907","markDefs":[],"children":[{"text":"Announced by Regeneron Pharmaceuticals on February 8, 2025, these findings, presented at Angiogenesis, Exudation, and Degeneration 2025, will support the submission of a supplemental Biologics License Application (sBLA) in Q1 2025.","_key":"ed090397e3f1","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"style":"normal","_key":"6ed80f6e9c0c","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“A higher concentration of VEGF inhibition might be beneficial because we have seen situations where there’s an unmet need in people with active disease on monthly therapy,” W. Lloyd Clark, MD, Palmetto Retinal Center, and assistant clinical professor of ophthalmology at the University of South Carolina School of Medicine told ","_key":"0b27d2b6781a"},{"_type":"span","marks":["em"],"text":"HCPLive","_key":"8f02c00f7a31"},{"marks":[],"text":". “One of the key takeaways from QUASAR is that we do see an additional benefit, not only in terms of durability but also efficacy and the ability to get these eyes under control with less frequent injections.”","_key":"6f2f149c3954","_type":"span"}],"_type":"block"},{"_type":"block","style":"normal","_key":"22d9d34f86b1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"A common cause of vision loss in adults, RVO is the second most frequent retinal vascular disease, occurring when there is a blockage in a retinal vein, leading to restricted blood flow and increased pressure in the eye. Those with RVO can experience sudden blurry vision or loss of vision, with ultimate serious complications such as macular edema.2","_key":"feb03b3fc558"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The US Food and Drug Administration approved aflibercept 8 mg for wet age-related macular degeneration (AMD), diabetic macular edema (DME), and diabetic retinopathy in August 2023.","_key":"d3586c876d40"},{"_type":"span","marks":["sup"],"text":"3","_key":"89cc4078c9e9"},{"_type":"span","marks":[],"text":" QUASAR is a global double-masked, active-controlled Phase 3 trial evaluating the efficacy and safety of aflibercept 8 mg in eyes with macular edema secondary to RVO, including central RVO (CRVO), branch RVO (BRVO), or hemiretinal RVO (HRVO).","_key":"d6ef7c393414"},{"_type":"span","marks":["sup"],"text":"1","_key":"0d0a4b7c7d28"}],"_type":"block","style":"normal","_key":"3c9688f9ee33"},{"markDefs":[],"children":[{"marks":[],"text":"Patients were randomized into three groups to receive either aflibercept every 8 weeks after 3 initial monthly doses, aflibercept 8 mg every 8 weeks after 5 initial monthly doses, or aflibercept 2 mg every 4 weeks. The trial’s primary endpoint was the mean change in best-corrected visual acuity (BCVA) through week 36, as measured by the Early Treatment Diabetic Retinopathy Study (ETDRS) letter score.","_key":"c73bf0116848","_type":"span"}],"_type":"block","style":"normal","_key":"ab2bcf9679e4"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"An analysis of QUASAR showed the trial met its primary endpoint, with both treatment cohorts of aflibercept 8 mg every 8 weeks achieving non-inferior BCVA gains to aflibercept 2 mg every 4 weeks. These results were consistent across patients with BRVO, CRVO, and HRVO. At 36 weeks, 88% of patients sustained an 8-week aflibercept 8 mg dosing schedule after 3 loading doses, increasing to 93% after 5 loading doses.","_key":"693692ac3f60"}],"_type":"block","style":"normal","_key":"74883a92a747"},{"_type":"block","style":"normal","_key":"1a6585c20759","markDefs":[],"children":[{"_key":"376c0eb3c94a","_type":"span","marks":[],"text":"Aflibercept 8 mg’s safety remained consistent with the known profile from pivotal trials, including low rates of intraocular inflammation (0.5%). Ocular treatment-emergent adverse events (TEAEs) were reported in ≥5% of all aflibercept 8 mg-treated patients, including increased ocular pressure (5%) and a single case each of endophthalmitis and retinal vasculitis."}]},{"markDefs":[],"children":[{"text":"“We’ve got ~15 years of clinical experience with the aflibercept molecule for the 2 mg formulation. Now, we’ve got a good body of evidence of 8 mg experience as well, and it appears that the safety profile of the 8 mg formulation is very similar to the 2 mg,” Clark told ","_key":"bc1658bbf6f5","_type":"span","marks":[]},{"text":"HCPLive","_key":"db3d7be2f774","_type":"span","marks":["em"]},{"_key":"1b357c15ba0f","_type":"span","marks":[],"text":". “Our confidence in the safety of the molecule appears to be pretty much irrespective of the concentration.”"}],"_type":"block","style":"normal","_key":"6a7b5e7f3b20"},{"markDefs":[],"children":[{"_key":"eb951cb9e8c8","_type":"span","marks":["em"],"text":"Disclosures: Relevant disclosures for Clark include Amgen, Genentech/Roche, Regeneron, and others."}],"_type":"block","style":"normal","_key":"b5b57b95661d"},{"_key":"6eea7633869d","markDefs":[],"children":[{"text":"References","_key":"179581da0f7e","_type":"span","marks":["strong"]}],"_type":"block","style":"normal"},{"listItem":"number","markDefs":[{"href":"https://newsroom.regeneron.com/news-releases/news-release-details/eylea-hdr-aflibercept-injection-8-mg-positive-phase-3-results","_key":"13a27e6cf3c9","_type":"link"}],"children":[{"_type":"span","marks":["sub"],"text":"Eylea HD® (aflibercept) injection 8 mg positive phase 3 results in patients with macular edema following retinal vein occlusion presented at Angiogenesis meeting. Regeneron Pharmaceuticals Inc. February 8, 2025. Accessed February 19, 2025. ","_key":"646abfc09f06"},{"_type":"span","marks":["13a27e6cf3c9","sub"],"text":"https://newsroom.regeneron.com/news-releases/news-release-details/eylea-hdr-aflibercept-injection-8-mg-positive-phase-3-results","_key":"d1b151042d09"},{"text":".","_key":"c1d06d704f37","_type":"span","marks":["sub"]}],"level":1,"_type":"block","style":"normal","_key":"64c59ac994d8"},{"listItem":"number","markDefs":[],"children":[{"_type":"span","marks":["sub"],"text":"Blair K, Czyz CN. Central Retinal Vein Occlusion. [Updated 2023 May 1]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK525985/","_key":"c609d312a344"}],"level":1,"_type":"block","style":"normal","_key":"4920670830ca"},{"_key":"f06f1b5ceb50","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":["sub"],"text":"Campbell P. Aflibercept 8 mg (eylea HD) approved by FDA for wet AMD, DME, and Diabetic retinopathy. HCP Live. August 23, 2023. Accessed February 19, 2025. https://www.hcplive.com/view/aflibercept-8mg-eylea-hd-approved-by-fda-for-wamd-dme-and-diabetic-retinopathy.","_key":"d7044e177312"}],"level":1,"_type":"block","style":"normal"}],"url":{"current":"aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md","_type":"slug"},"link":"/view/aflibercept-8-mg-noninferior-for-rvo-in-quasar-with-w-lloyd-clark-md","_createdAt":"2025-02-19T21:09:58Z","_rev":"ivaRGNxFBepXyTXsuMherr","ExcludeFromPubMedXML":false,"_type":"article","title":"Aflibercept 8 mg Noninferior for RVO in QUASAR with W. Lloyd Clark, MD","_id":"d4083e60-03e8-4e5d-8404-9f97c8c5d98b","_updatedAt":"2025-02-19T23:00:04Z","summary":null,"contentCategory":{"_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos"},"thumbnail":{"asset":{"extension":"jpg","_id":"image-6d87f07338586a48041ba67e900189789aa40d8a-300x300-jpg","originalFilename":"W. Lloyd Clark, MD.jpeg","metadata":{"isOpaque":true,"blurHash":"eIG8yO?H5kNG^j~VRPpIbIIA9FRjRQazoeENofrWs:x^XSay%2ayM{","_type":"sanity.imageMetadata","palette":{"lightMuted":{"population":7.65,"background":"#c2a499","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0,"background":"#3a74c4"},"dominant":{"background":"#c2a499","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":7.65},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":2.59,"background":"#604234","_type":"sanity.imagePaletteSwatch"},"muted":{"background":"#a3715e","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.79},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":4.83,"background":"#e0a491"},"darkVibrant":{"background":"#0b1625","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.02}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":300,"aspectRatio":1,"height":300}},"_rev":"BpNdyQCG1dl0w7WYXlIgvj","sha1hash":"6d87f07338586a48041ba67e900189789aa40d8a","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg","_createdAt":"2023-11-05T17:22:08Z","_updatedAt":"2023-11-05T17:22:08Z","_type":"sanity.imageAsset","mimeType":"image/jpeg","assetId":"6d87f07338586a48041ba67e900189789aa40d8a","uploadId":"TTF2WdHDaiIZTf2ZMQ6iguHLdrxvluOA","path":"images/0vv8moc6/hcplive/6d87f07338586a48041ba67e900189789aa40d8a-300x300.jpg","size":15600}},"is_visible":true,"taxonomyMapping":[{"_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy"},{"_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}]}],"_type":"taxonomy","identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z"},{"_type":"taxonomy","name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn"},{"pixelTrackingCode":{"_ref":"21fa5627-6528-45fb-938c-762770c2a663","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"L7yG3IvIye3EpJsuLI6lj5","name":"Ophthalmology","_id":"topic_ophthalmology","summary":[{"children":[{"marks":[],"text":"On the ","_key":"b608c592ab02","_type":"span"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"cdba8d4004fe"},{"_type":"span","marks":[],"text":"Ophthalmology page, resources on the topics of medical news and expert insight into ophthalmic disease can be found. Content includes articles, interviews, videos, podcasts, and breaking news on eye disease research, treatment, and drug development.","_key":"34b8afe797af"}],"_type":"block","style":"normal","_key":"7f7e7f1fc48d","markDefs":[]}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"cmeType":"per","_type":"taxonomy","_updatedAt":"2023-03-30T18:45:07Z","identifier":"ophthalmology","perKeywordMapping":["Ophthalmology","Optometry"]}],"articleType":"News"},{"display_summary":true,"authorMapping":[{"url":{"current":"tim-smith","_type":"slug"},"lastName":"Smith","_rev":"4cB9C6CTf03w1NIxZziTKh","biography":[{"_type":"block","style":"normal","_key":"7bbc0f222f10","markDefs":[{"_type":"link","href":"mailto:tsmith@mjhlifesciences.com","_key":"61fa5a3c02ca"}],"children":[{"_type":"span","marks":[],"text":"Tim Smith joined the MJH Life Sciences team as an assistant editor for HCPLive in August 2022. He graduated from UC Berkeley with a degree in political science, working in multimedia journalism as a staff writer prior to joining MJH. In his spare time, he enjoys reading, watching TV, listening to podcasts, and rock climbing. You can contact him at ","_key":"b4511b246e190"},{"_type":"span","marks":["61fa5a3c02ca"],"text":"tsmith@mjhlifesciences.com","_key":"b4511b246e191"},{"text":".","_key":"b4511b246e192","_type":"span","marks":[]}]}],"firstName":"Tim","displayName":"Tim Smith","_createdAt":"2022-08-24T19:55:19Z","_type":"author","_id":"50390873-f609-4f23-b2f5-a613c054c1ac","_updatedAt":"2022-08-24T19:55:19Z"},{"_updatedAt":"2025-02-19T20:51:44Z","url":{"current":"shuai-steve-xu-md-msc-","_type":"slug"},"lastName":"Xu","authorType":"expert","displayName":"Shuai (Steve) Xu, MD, MSc,","_createdAt":"2025-02-19T20:50:42Z","biography":[{"children":[{"_type":"span","marks":[],"text":"Shuai (Steve) Xu, MD, MSc, is a dermatologist, a physician-engineer, Ruth K. Freinkel MD professor at the Feinberg School of Medicine, and the CEO and co-founder of Sibel Health.","_key":"df24eae89b0f"}],"_type":"block","style":"normal","_key":"6ab515583079","markDefs":[]}],"firstName":"Shuai","_rev":"ivaRGNxFBepXyTXsuLIuFf","_type":"author","_id":"78fa0cd9-2776-4302-896f-5a89ba42b902"},{"firstName":"Kailas","_rev":"cID2mV6fSdv64jOtmNO3tD","_type":"author","biography":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Kailas Vodrahalli is a PhD student in electrical engineering at Stanford University.","_key":"65e7c384e558"}],"_type":"block","style":"normal","_key":"01574dbca066"}],"lastName":"Vodrahalli","authorType":"expert","displayName":"Kailas Vodrahalli","_createdAt":"2025-02-19T20:52:15Z","_id":"f1533e36-645d-4bdf-8f90-79f48249afa8","_updatedAt":"2025-02-19T20:53:01Z","url":{"_type":"slug","current":"kailas-vodrahalli"}},{"_type":"author","_id":"ccc201c0-04d8-4f0b-bbbe-1c6521d1d395","biography":[{"style":"normal","_key":"eecc86f4dfc6","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Harald Kittler, MD, is a professor of dermatology for the Medical University of Vienna.","_key":"f77deceb991b"}],"_type":"block"}],"_updatedAt":"2025-02-19T20:50:14Z","url":{"current":"harald-kittler-md","_type":"slug"},"firstName":"Harald","lastName":"Kittler","displayName":"Harald Kittler, MD","authorType":"expert","_createdAt":"2025-02-19T20:49:15Z","_rev":"Fd1jDX9jbPHQLM4yboIalQ"}],"is_visible":true,"articleType":"News","_type":"article","summary":"In this feature, 3 experts highlight their own research on new technological advances and their views on the benefits and drawbacks of artificial intelligence in dermatology.","_createdAt":"2025-02-19T19:29:04Z","published":"2025-02-19T21:00:13.952Z","_updatedAt":"2025-02-20T16:29:14Z","url":{"current":"ai-in-dermatology-emerging-insights-and-diverging-perspectives","_type":"slug"},"seoTag":["AI","artificial intelligence","atopic dermatitis","AD","feature"],"contentCategory":{"name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory"},"taxonomyMapping":[{"identifier":"dermatology","perKeywordMapping":["Dermatology","Dermatologic Cancer"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_rev":"uvXJooXtzvjNOyx50DtOz4","_type":"taxonomy","_updatedAt":"2023-03-30T18:37:18Z","summary":[{"_type":"block","style":"normal","_key":"2d374a27e197","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.","_key":"bfe5d86caad9"}]}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"isMainTopic":false,"name":"Dermatology","_id":"topic_dermatology"},{"identifier":"atopic-dermatitis","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"2sK05ae9cc6f2xw80LsqdL","name":"Atopic Dermatitis","_updatedAt":"2024-10-23T13:10:35Z","summary":[{"children":[{"_key":"9faef397dc21","_type":"span","marks":[],"text":"On the "},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"95494ef9d956"},{"_key":"a55149ee5114","_type":"span","marks":[],"text":"Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development."}],"_type":"block","style":"normal","_key":"f61ee45b707b","markDefs":[]}],"pixelTrackingCode":{"_ref":"e4b5b2a6-8742-42cb-bf97-fa1a8bfd2d53","_type":"reference"},"_type":"taxonomy","_id":"topic_atopic-dermatitis"},{"_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"_key":"05eda7184d6f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy"},{"identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}]}],"_type":"taxonomy"},{"_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy","name":"Videos"}],"_rev":"o0lY0lMSCBNEoNDZvetxwW","_id":"674b3cf3-e594-4131-9da6-2fe424ed0e8a","thumbnail":{"asset":{"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg","size":51651,"_createdAt":"2025-02-19T19:32:36Z","extension":"jpg","_id":"image-27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400-jpg","uploadId":"sYZms91fzvjjN6B1LX6iGV7RgtDdqaHy","_rev":"ivaRGNxFBepXyTXsuKWZnp","mimeType":"image/jpeg","metadata":{"palette":{"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000","population":0,"background":"#e4cca4"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":8.72,"background":"#4a321c"},"lightMuted":{"title":"#fff","population":7.77,"background":"#c5bdb0","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"population":0,"background":"#d4a880","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"dominant":{"foreground":"#000","title":"#fff","population":9.51,"background":"#aa9676","_type":"sanity.imagePaletteSwatch"},"_type":"sanity.imagePalette","darkMuted":{"background":"#57452d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.24},"muted":{"population":9.51,"background":"#aa9676","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":400,"aspectRatio":1,"height":400},"isOpaque":true,"blurHash":"ekL4g0%M%MWBt7?wR*azWAR*-:RiWBR*WBD*RjxaofofxaozWCt7WV","_type":"sanity.imageMetadata"},"_type":"sanity.imageAsset","sha1hash":"27b7211cf03e0b68aaeb16548693de243d74bfd7","path":"images/0vv8moc6/hcplive/27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400.jpg","assetId":"27b7211cf03e0b68aaeb16548693de243d74bfd7","_updatedAt":"2025-02-19T19:32:36Z","originalFilename":"pexels-ivan-samkov-4989171.jpg"}},"body":[{"_type":"youtube","_key":"ba7dbe811a73","url":"https://youtu.be/g8c9P11gohs","videoObject":{"videoDescription":"Artificial Intelligence in Dermatology: Emerging Insights and Diverging Perspectives","_type":"videoDetails","videoTitle":"AI in Dermatology: Emerging Insights and Diverging Perspectives","thumbnail":{"_type":"image","asset":{"_type":"reference","_ref":"image-27b7211cf03e0b68aaeb16548693de243d74bfd7-400x400-jpg"}},"videoDuration":"PT17M01S"}},{"children":[{"marks":[],"text":"Artificial intelligence (AI) technology may be transforming the field of ","_key":"a6d328e1f704","_type":"span"},{"_type":"span","marks":["3e0d18731084"],"text":"dermatology","_key":"7ba3684e1a93"},{"_key":"b7a94bc2593f","_type":"span","marks":[],"text":", providing clinicians and patients with faster diagnoses, greater diagnostic accuracy, and expanded access to health care. The topic is rapidly becoming one of the most debated in medicine, driven by a heated clash between supporters and skeptics over whether it will truly benefit patients."}],"_type":"block","style":"normal","_key":"091f000e1b69","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/clinical/dermatology","_key":"3e0d18731084"}]},{"markDefs":[],"children":[{"text":"A plethora of recent studies have been published regarding new types of AI technology and their use in dermatology. In this ","_key":"7710498cd8c9","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive","_key":"30a2ef7dfd2d"},{"_type":"span","marks":[],"text":" feature, 3 speakers were interviewed regarding their contributions to recent AI-related studies in dermatology as well as their more general impressions of the heightened interest in further implementing AI in medicine.","_key":"e90b16a09c47"}],"_type":"block","style":"normal","_key":"abaaedb2eb32"},{"_key":"a3c8b8e405e4","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The feature included an interview with Harald Kittler, MD, a professor of dermatology for the Medical University of Vienna, whose international research team had evaluated a learning method in which the accuracy of AI results incorporated human decision-making criteria. The study, which demonstrated a 12% improvement in correct skin cancer diagnoses made by dermatologists, was published in Nature Medicine.","_key":"3938807b8b36"},{"_type":"span","marks":["sup"],"text":"1","_key":"7c917bb36e43"}],"_type":"block","style":"normal"},{"style":"normal","_key":"fc6b630abc45","markDefs":[],"children":[{"_type":"span","marks":[],"text":"An interview was also conducted with Kailas Vodrahalli, a PhD student in electrical engineering at Stanford University. Vodrahilli touched upon his own team’s research, involving an evaluation of an AI decision support tool using a machine learning algorithm and determining whether the tool could improve the telemedicine-submitted image quality by providing real-time responses to patients. The study concluded that the AI decision support tool’s use, along with their machine learning algorithm, was linked to improvements in the quality of skin disease photographs.","_key":"1346ec97de3f"},{"_type":"span","marks":["sup"],"text":"2","_key":"f1b3e6bc54a1"}],"_type":"block"},{"markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/view/ai-enabled-wearable-sensor-useful-reducing-scratching-atopic-dermatitis","_key":"d31c07490374","nofollow":true}],"children":[{"_type":"span","marks":[],"text":"This feature also included an interview with Shuai (Steve) Xu, MD, MSc, a dermatologist, physician engineer, Ruth K. Freinkel MD professor at the Feinberg School of Medicine, and CEO of Sibel Health. His research pointed to the efficacy of the use of haptic feedback on an ","_key":"6af9ca1f075a"},{"_key":"95324ee9bc72","_type":"span","marks":["d31c07490374"],"text":"AI-enabled wearable device"},{"_type":"span","marks":[],"text":", with occurrences of nocturnal scratching decreasing among adult patients suffering from mild atopic dermatitis.","_key":"ecda47e3b94c"},{"_type":"span","marks":["sup"],"text":"3","_key":"14935d70055c"}],"_type":"block","style":"normal","_key":"e5fb1fb43c95"},{"children":[{"marks":[],"text":"Kittler, Xu, and Vodrahilli addressed their own findings and discuss the general discourse surrounding AI’s use in dermatology. Each expert’s unique insights, given their differing specialties and backgrounds, allow for an update on new AI research and any current progress AI technology has had in reshaping skin disease detection, clinical decision-making enhancement, and pushing the boundaries of dermatological care.","_key":"b79de8dcfdd1","_type":"span"}],"_type":"block","style":"normal","_key":"60444e33ab2f","markDefs":[]},{"_type":"block","style":"normal","_key":"f800bd015eaa","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Check out the feature video posted above to discover more about the findings uncovered by these experts.","_key":"1ee0084ff443"}]},{"style":"normal","_key":"5ce174feba12","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Kittler received nonfinancial support from Derma Medical Systems, Fotofinder and Heine, and speaker fees from Fotofinder. Vodrahalli reported receiving grants from the National Science Foundation (NSF) Graduate Research Fellowships Program during the conduct of the study and had a patent for Automated Clinical Image Quality Assessment pending for the work in this study. Xu reported grants from Maruho Co Ltd during the conduct of his study, serves on the advisory board for AbbVie outside the submitted work, and has a patent for WO2023183258 pending.","_key":"33f14a9b5d0d"}],"_type":"block"},{"_key":"ad83430c5f32","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"References","_key":"25e7440a6688"}],"_type":"block","style":"normal"},{"level":1,"_type":"block","style":"h6","_key":"376ee51659c1","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Barata C, Rotemberg V, Codella NCF, Tschandl P, Rinner C, Akay BN, Apalla Z, Argenziano G, Halpern A, Lallas A, Longo C, Malvehy J, Puig S, Rosendahl C, Soyer HP, Zalaudek I, Kittler H. A reinforcement learning model for AI-based decision support in skin cancer. Nat Med. 2023 Aug;29(8):1941-1946. doi: 10.1038/s41591-023-02475-5. Epub 2023 Jul 27. PMID: 37501017; PMCID: PMC10427421.","_key":"d49f1af7e9fd"}]},{"_key":"1264276a9cec","listItem":"number","markDefs":[],"children":[{"text":"Vodrahalli K, Ko J, Chiou AS, Novoa R, Abid A, Phung M, Yekrang K, Petrone P, Zou J, Daneshjou R. Development and Clinical Evaluation of an Artificial Intelligence Support Tool for Improving Telemedicine Photo Quality. JAMA Dermatol. 2023 May 1;159(5):496-503. doi: 10.1001/jamadermatol.2023.0091. PMID: 36920380; PMCID: PMC10018405.","_key":"af3adb0d337a","_type":"span","marks":[]}],"level":1,"_type":"block","style":"h6"},{"style":"h6","_key":"25cd9ff41638","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Yang AF, Patel S, Chun KS, et al. Artificial Intelligence–Enabled Wearable Devices and Nocturnal Scratching in Mild Atopic Dermatitis. JAMA Dermatol. Published online February 05, 2025. doi:10.1001/jamadermatol.2024.5697.","_key":"86ce3f0000fc"}],"level":1,"_type":"block"}],"link":"/view/ai-in-dermatology-emerging-insights-and-diverging-perspectives","ExcludeFromPubMedXML":false,"title":"AI in Dermatology: Emerging Insights and Diverging Perspectives"},{"articleType":"News","_updatedAt":"2025-02-18T21:18:37Z","summary":"The February 18, 2025 SOCS News Update highlights SOCS mentorship opportunities as well as the importance of mentors and role models.","published":"2025-02-18T21:00:45.259Z","display_summary":true,"is_visible":true,"thumbnail":{"asset":{"metadata":{"palette":{"lightVibrant":{"title":"#fff","population":0,"background":"#fca474","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"population":0,"background":"#713112","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"title":"#fff","population":0.02,"background":"#d7c4ac","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"background":"#ce5a22","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.03},"dominant":{"background":"#3f322a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.47},"_type":"sanity.imagePalette","darkMuted":{"title":"#fff","population":0.47,"background":"#3f322a","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"muted":{"title":"#fff","population":0.33,"background":"#a57055","_type":"sanity.imagePaletteSwatch","foreground":"#fff"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,/9j/2wBDAAYEBQYFBAYGBQYHBwYIChAKCgkJChQODwwQFxQYGBcUFhYaHSUfGhsjHBYWICwgIyYnKSopGR8tMC0oMCUoKSj/2wBDAQcHBwoIChMKChMoGhYaKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCgoKCj/wAARCAANABQDASIAAhEBAxEB/8QAGQAAAgMBAAAAAAAAAAAAAAAAAAECAwQI/8QAHxAAAQUAAQUAAAAAAAAAAAAAAQACAxEhBBNBUVJx/8QAFAEBAAAAAAAAAAAAAAAAAAAAAf/EABYRAQEBAAAAAAAAAAAAAAAAAAABEf/aAAwDAQACEQMRAD8A6dl5cjbLIrAsb5VbObM5uwgH6t5aDeDUumz1CMp2FE8vjDiKJ7IUwKFBCQ//2Q==","dimensions":{"_type":"sanity.imageDimensions","width":4176,"aspectRatio":1.5806207418622256,"height":2642},"isOpaque":true,"blurHash":"VES~q;tRx]xabvxuWqofoLbb?wofM{kDe-?vsmRjWXjE","_type":"sanity.imageMetadata"},"uploadId":"UkWU0x248b0tvJWbTkE2uO8lY7FzTZnJ","_rev":"d85e4RNWNOToFCQ826spTr","_type":"sanity.imageAsset","mimeType":"image/jpeg","size":467261,"assetId":"5b991868daab2ad6287b75ffd968ecd8e44181a7","originalFilename":"HCPLive SOCS Logo update.jpg","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg","path":"images/0vv8moc6/hcplive/5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642.jpg","_createdAt":"2025-01-06T12:59:58Z","_updatedAt":"2025-01-06T12:59:58Z","sha1hash":"5b991868daab2ad6287b75ffd968ecd8e44181a7","extension":"jpg","_id":"image-5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642-jpg"}},"ExcludeFromPubMedXML":false,"_createdAt":"2025-02-18T18:29:47Z","_type":"article","seoTag":["SOCS","skin of color","Skin of Color Savvy"],"authorMapping":[{"lastName":"Oliver","displayName":"Brittany Oliver, MD, FAAD","_rev":"Fd1jDX9jbPHQLM4ybhr2X3","_type":"author","_id":"823b6f70-ee21-42b4-8c83-8a2387b79262","url":{"current":"brittany-oliver-md-faad","_type":"slug"},"firstName":"Brittany","authorType":"expert","_createdAt":"2025-02-18T18:08:44Z","biography":[{"children":[{"_key":"291bfe2fb373","_type":"span","marks":[],"text":"Brittany Oliver, MD, FAAD is a board-certified dermatologist practicing in Kansas City, Missouri, with a special interest in pigmentary disorders and hair loss, and a member of the Skin of Color Society."}],"_type":"block","style":"normal","_key":"0610ca61599d","markDefs":[]}],"_updatedAt":"2025-02-18T18:08:44Z"},{"_id":"50390873-f609-4f23-b2f5-a613c054c1ac","_updatedAt":"2022-08-24T19:55:19Z","url":{"current":"tim-smith","_type":"slug"},"lastName":"Smith","_rev":"4cB9C6CTf03w1NIxZziTKh","biography":[{"_type":"block","style":"normal","_key":"7bbc0f222f10","markDefs":[{"_type":"link","href":"mailto:tsmith@mjhlifesciences.com","_key":"61fa5a3c02ca"}],"children":[{"_type":"span","marks":[],"text":"Tim Smith joined the MJH Life Sciences team as an assistant editor for HCPLive in August 2022. He graduated from UC Berkeley with a degree in political science, working in multimedia journalism as a staff writer prior to joining MJH. In his spare time, he enjoys reading, watching TV, listening to podcasts, and rock climbing. You can contact him at ","_key":"b4511b246e190"},{"_type":"span","marks":["61fa5a3c02ca"],"text":"tsmith@mjhlifesciences.com","_key":"b4511b246e191"},{"text":".","_key":"b4511b246e192","_type":"span","marks":[]}]}],"firstName":"Tim","displayName":"Tim Smith","_createdAt":"2022-08-24T19:55:19Z","_type":"author"}],"body":[{"markDefs":[{"_type":"link","href":"https://www.hcplive.com/podcasts/socs-podcast","_key":"ce88edcf2b4d"}],"children":[{"_type":"span","marks":["strong"],"text":"Welcome to","_key":"f9d0c3c6b939"},{"text":" ","_key":"1eab3a2493f9","_type":"span","marks":[]},{"_type":"span","marks":["strong","em","ce88edcf2b4d"],"text":"Skin of Color Savvy: The Art and Science of Treating Patients of Color","_key":"dabe9bfe6423"},{"_type":"span","marks":["strong","em"],"text":"!","_key":"acbaa85621c8"}],"_type":"block","style":"h4","_key":"434ee627b0dc"},{"_type":"video","videoID":"6369009365112","disableAutoPlayVideo":false,"source":"brightcove","_key":"67ab3135d07f","videoObject":{"videoTitle":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","thumbnail":{"_type":"image","asset":{"_ref":"image-5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642-jpg","_type":"reference"}},"videoDuration":"PT10M30S","videoDescription":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","_type":"videoDetails"}},{"_key":"b06eb688b00e","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/","_key":"dbcd0607488e"}],"children":[{"text":"In this News Update, part of the ","_key":"d83bec4493fd","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"Skin of Color Savvy: The Art and Science of Treating Patients of Color ","_key":"d29fd44d097e"},{"marks":[],"text":"series, Brittany Oliver, MD, FAAD, speaks about the pivotal role of mentorship in dermatology and the initiatives led by the ","_key":"2bc0a51fad0e","_type":"span"},{"_type":"span","marks":["dbcd0607488e"],"text":"Skin of Color Society (SOCS)","_key":"2dd459aa9c87"},{"_type":"span","marks":[],"text":" to foster professional development. Oliver emphasizes the profound impact of mentorship on career trajectories, highlighting how meaningful mentor-mentee relationships extend beyond networking to shape clinical expertise, confidence, and leadership in the field.","_key":"e67f647c971c"}],"_type":"block","style":"normal"},{"style":"normal","_key":"ad0936f3e306","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/what-we-do/mentorship/observership-grant","_key":"b1ea10a929aa"},{"_type":"link","href":"https://skinofcolorsociety.org/what-we-do/mentorship/mentorship-program","_key":"9e9490fbdf70","nofollow":true,"blank":true}],"children":[{"_type":"span","marks":[],"text":"She discusses SOCS’s commitment to mentorship as one of its core pillars, detailing key programs such as the ","_key":"d777f16c90a1"},{"_type":"span","marks":["9e9490fbdf70"],"text":"SOCS Mentorship Program","_key":"0ff7853312f7"},{"_type":"span","marks":[],"text":", the ","_key":"bab825e31dbc"},{"_type":"span","marks":["b1ea10a929aa"],"text":"Observership Grant","_key":"3de44fdccc5e"},{"_type":"span","marks":[],"text":", and the newly launched Diversity in Clinical Research Mentorship Program. These initiatives aim to support early-career dermatologists, underrepresented minority (URM) investigators, and students pursuing careers in dermatology.","_key":"a9ca05c21705"}],"_type":"block"},{"_key":"8cc74dd8c14f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"In honor of Black History Month, Oliver reflects on the influential mentors who shaped her journey, including Adam Friedman, MD, and SOCS founder Susan Taylor, MD, whose dedication to mentorship and advocacy has left a lasting impact on the specialty. She also shares her perspective on the importance of increasing diversity in medicine, encouraging dermatologists to engage in outreach, advocacy, and structural changes to address healthcare disparities.","_key":"7f615781e171"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"a3adaf4c0f21","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Finally, in recognition of American Heart Month, the discussion turns to the intersection of dermatology and cardiovascular disease, particularly within communities of color. Oliver underscores the need for systemic solutions, early pipeline programs, and physician-led advocacy to improve representation and access to care. She calls on her colleagues to take an active role in addressing disparities, emphasizing the power of physicians to effect meaningful change beyond the clinic.","_key":"2a3fde89a733"}]},{"children":[{"_type":"span","marks":[],"text":"To learn more about SOCS’s mentorship programs and initiatives, visit ","_key":"51e682970cf7"},{"_type":"span","marks":["89fe9163ac80"],"text":"Skin of Color Society","_key":"95bd4dee2d3f"},{"_key":"58358f10b8f8","_type":"span","marks":[],"text":"."}],"_type":"block","style":"normal","_key":"590154abb6f7","markDefs":[{"_type":"link","href":"https://www.skinofcolorsociety.org","_key":"89fe9163ac80"}]}],"_id":"0d93cfd0-4dbd-4134-ae47-9525a0ee8193","taxonomyMapping":[{"usedForRecommendations":false,"video":{"isTaxVideo":false},"videoPlayerConfig":{"brightcoveAccountID":"5436121609001"},"_createdAt":"2025-01-02T19:46:49Z","thumbnail":{"alt":"Skin of Color Savvy: The Art and Science of Treating Patients of Color","asset":{"_ref":"image-5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642-jpg","_type":"reference"},"default":true,"_type":"mainImage"},"_type":"taxonomy","summary":[{"children":[{"text":"Hosted by Skin of Color Society and produced by HCPLive, ","_key":"f42a2082d6be0","_type":"span","marks":[]},{"_type":"span","marks":["em","strong"],"text":"Skin of Color Savvy","_key":"e8ad63835733"},{"_type":"span","marks":[],"text":" delves into the latest research, clinical insights, and culturally competent care practices in dermatology with leading experts. ","_key":"70324529cf18"}],"_type":"block","style":"normal","_key":"3290b34aeb0e","markDefs":[]},{"style":"normal","_key":"928832735b24","markDefs":[],"children":[{"marks":[],"text":"Whether it’s groundbreaking research, practice-changing insights, or highlights from the SOCS community, this twice-monthly program provides dermatologists and care providers with expert perspectives on treating patients with skin of color.","_key":"bfefe716baee","_type":"span"}],"_type":"block"},{"_type":"block","style":"normal","_key":"c54c3d15b3a4","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"a548861217bb"}]}],"parent":{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference"},"taxonomyArchived":false,"_id":"d9a8cdb1-b21c-45a1-a1b4-0f2e14d4c5f9","_updatedAt":"2025-01-06T15:27:38Z","identifier":"socs-podcast","showTaxonomyImage":true,"name":"Skin of Color Savvy: The Art and Science of Treating Patients of Color","isMainTopic":true,"_rev":"AR6qoypNcER7zlbM0tqoZG"},{"name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"style":"normal","_key":"05eda7184d6f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z"},{"_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy","name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos"},{"_type":"taxonomy","_updatedAt":"2023-03-30T18:37:18Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.","_key":"bfe5d86caad9"}],"_type":"block","style":"normal","_key":"2d374a27e197"}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"isMainTopic":false,"name":"Dermatology","_id":"topic_dermatology","identifier":"dermatology","perKeywordMapping":["Dermatology","Dermatologic Cancer"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_rev":"uvXJooXtzvjNOyx50DtOz4"},{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"3b1c50e6e15b"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"c9b6f58fcd46"},{"_type":"span","marks":[],"text":"podcasts page features a feed of medical news and interview podcast series, including DocTalk, Lungcast, Derm Discussions, and Heart Trials.","_key":"fb5df9c2d5d3"}],"_type":"block","style":"normal","_key":"dea2cb0508c7"}],"identifier":"podcasts","_createdAt":"2020-07-08T03:27:37Z","_rev":"AR6qoypNcER7zlbM0q7CE8","_type":"taxonomy","_updatedAt":"2025-01-04T14:41:58Z","name":"Podcasts","_id":"71feb86d-3e1f-46c8-9508-28c43eddc1bc"},{"usedForRecommendations":false,"video":{"isTaxVideo":false},"_updatedAt":"2024-12-09T19:21:19Z","identifier":"alopecia","parent":{"_ref":"topic_dermatology","_type":"reference"},"_type":"taxonomy","name":"Alopecia","taxonomyArchived":false,"_id":"6693c91c-812d-4480-a9bc-4deb0db0d7aa","videoPlayerConfig":{"brightcoveAccountID":"5436121609001"},"_createdAt":"2024-12-09T19:20:32Z","_rev":"EnjHxnWG7nhsRUiWfzaeNo"}],"_rev":"Fd1jDX9jbPHQLM4ybidhou","contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"link":"/view/skin-of-color-savvy-news-update-addressing-disparities-black-history-month-mentorship-opportunities","title":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","url":{"current":"skin-of-color-savvy-news-update-addressing-disparities-black-history-month-mentorship-opportunities","_type":"slug"}},{"published":"2025-02-17T15:00:00.000Z","contentCategory":{"_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u"},"_createdAt":"2025-02-15T21:26:05Z","articleType":"News","_updatedAt":"2025-02-18T17:54:51Z","ExcludeFromPubMedXML":false,"_type":"article","link":"/view/the-medical-sisterhood-white-coats-wingmen-how-men-can-uplift-women-in-medicine","display_summary":true,"thumbnail":{"asset":{"extension":"png","uploadId":"1SqDYpNOdaaNtxtVbCdeiJG5cmTuPvtj","_type":"sanity.imageAsset","_createdAt":"2025-02-18T17:53:32Z","originalFilename":"Podcast Square Thumbs (4).png","sha1hash":"48a42c96bb84d8067d9522bd8af433c69b4dea94","path":"images/0vv8moc6/hcplive/48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png","size":690849,"assetId":"48a42c96bb84d8067d9522bd8af433c69b4dea94","metadata":{"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1200,"aspectRatio":1,"height":1200},"isOpaque":true,"blurHash":"eMPOlS.RMe#=~X-;t%V[VuR%^S-;s,NZE0TqMyV@oy%MXPS^nOoftk","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":7.74,"background":"#452a2d","_type":"sanity.imagePaletteSwatch"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.76,"background":"#926b48"},"lightVibrant":{"population":0.3,"background":"#f1dd8c","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.1,"background":"#8d2c3d"},"lightMuted":{"foreground":"#000","title":"#fff","population":0.3,"background":"#d4afc7","_type":"sanity.imagePaletteSwatch"},"vibrant":{"title":"#fff","population":0.01,"background":"#ec3794","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"background":"#452a2d","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.74}}},"_rev":"Fd1jDX9jbPHQLM4ybhpFpE","mimeType":"image/png","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200.png","_id":"image-48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200-png","_updatedAt":"2025-02-18T17:53:32Z"}},"seoTag":["Medical Sisterhood"],"_rev":"cID2mV6fSdv64jOtmIZY2i","body":[{"_key":"50acbc5aa284","markDefs":[{"href":"https://www.hcplive.com/podcasts/the-medical-sisterhood","_key":"499400732db0","nofollow":true,"blank":true,"_type":"link"}],"children":[{"text":"Welcome to ","_key":"a28f77ad8800","_type":"span","marks":["strong"]},{"marks":["499400732db0","strong"],"text":"The Medical Sisterhood","_key":"846f4948e78a","_type":"span"},{"_type":"span","marks":["strong"],"text":"!","_key":"95f7e8cb1527"}],"_type":"block","style":"h3"},{"videoID":"6368844108112","disableAutoPlayVideo":false,"source":"brightcove","_key":"d8aeee7001a2","videoObject":{"thumbnail":{"asset":{"_type":"reference","_ref":"image-f81770312840bfdf57d9d5ab4423dde0f4be7f78-1200x1200-png"},"_type":"image"},"videoDuration":"PT27M25S","videoDescription":"The Medical Sisterhood: White Coats \u0026 Wingmen—How Men Can Uplift Women in Medicine","_type":"videoDetails","videoTitle":"The Medical Sisterhood: White Coats \u0026 Wingmen—How Men Can Uplift Women in Medicine"},"_type":"video"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"In the latest episode of ","_key":"c67688050640"},{"text":"The Medical Sisterhood","_key":"1af724d92c1e","_type":"span","marks":["em"]},{"_key":"09638af3dcdf","_type":"span","marks":[],"text":", host Mona Shahriari, MD, an assistant clinical professor of dermatology at the Yale University School of Medicine and the associate director of clinical trials at Central Connecticut Dermatology Research, spoke alongside James Q. Del Rosso, DO, research director of JDR Dermatology Research and president of the American Acne and Rosacea Society, to discuss the empowerment of women in medicine, the impact of male and female role models for clinicians, and more."}],"_type":"block","style":"normal","_key":"8261e7767972"},{"_type":"sidebar","caption":"Key Highlights","_key":"19e9d071cc25","content":[{"_key":"c558a39dcc63","markDefs":[],"children":[{"marks":["strong"],"text":"0:00 Introduction of James Del Rosso, DO","_key":"2a4298907bf9","_type":"span"}],"_type":"block","style":"normal"},{"style":"normal","_key":"4c3b0736f0a9","markDefs":[],"children":[{"_key":"b1179618c55c","_type":"span","marks":["strong"],"text":"01:37 Early experiences in medical school"}],"_type":"block"},{"_key":"ad8f3136f2fc","markDefs":[],"children":[{"marks":["strong"],"text":"04:16 Female role models and childhood experiences","_key":"59dc6111df63","_type":"span"}],"_type":"block","style":"normal"},{"_key":"daf334c7772e","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"11:24 Aunt's role in impacting the world","_key":"e52f3154cbcf"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"cf1896ddbb26","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"12:27 Societal pressures for women","_key":"d57daad1ec5e"}]},{"children":[{"_type":"span","marks":["strong"],"text":"14:46 Experiences as a male in medicine","_key":"7ff63a14b2d6"}],"_type":"block","style":"normal","_key":"68daa29319e1","markDefs":[]},{"_key":"b59f82f672e3","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"19:47 Closing messages","_key":"7c0462f90c6c"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":["strong"],"text":"25:51 Perspectives on life","_key":"718d257e11b8"}],"_type":"block","style":"normal","_key":"dd54d0023be2","markDefs":[]},{"_key":"924adafa7106","markDefs":[],"children":[{"marks":["strong"],"text":"26:57 Conclusion ","_key":"dcdd95df42ce","_type":"span"}],"_type":"block","style":"normal"}]},{"_type":"block","style":"normal","_key":"3605e362d8f1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"After introducing Del Rosso, Shahriari highlighted her friendship with Del Rosso and their careers in the field of dermatology. She asked Del Rosso to discuss various elements of his extensive career in dermatology and his journey toward becoming a clinician. Del Rosso described his family’s history, including his own Italian-American heritage and his early life in Brooklyn, New York. Del Rosso noted his own access to an array of intelligent role models in his youth, with both male and female figures helping him to shape his future.","_key":"52707ecf0145"}]},{"markDefs":[],"children":[{"text":"Del Rosso touched on various elements of his early career, pointing to his own choices regarding choosing a medical school that fit both his academic and financial needs. He expressed satisfaction at his choice to attend Ohio University Heritage College of Osteopathic Medicine over other academic institutions, highlighting his positive experiences with such figures as Wilma Bergfeld, MD.","_key":"ef58ba8501d2","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"41bb3e498c8a"},{"_key":"84c65e4ecd06","markDefs":[],"children":[{"marks":[],"text":"Over the course of the episode, the conversation shifted to the unique benefits of having had a variety of influential female role models in one’s younger years. Del Rosso noted that, as a young person, his mother, aunts, and grandparents all set strong examples for him. Shahriari spoke with Del Rosso about his familial history prior to his career in dermatology. Specifically, she spoke to Del Rosso about the profound role his aunt and sister had in his life and in helping to shape him as an individual.","_key":"5c50b968e54f","_type":"span"}],"_type":"block","style":"normal"},{"children":[{"marks":[],"text":"The discussion between Shahriari and Del Rosso further evolved into a conversation regarding pressures faced by women in the field of dermatology and the empowerment of female colleagues by male allies. Del Rosso commented on his own challenges in persevering throughout his career in medicine. The conversation was punctuated with a point about resilience in one's own career, continuing to move forward regardless of the varying opinions and views of others.","_key":"71a44e1e95e6","_type":"span"}],"_type":"block","style":"normal","_key":"5df783fb71e8","markDefs":[]},{"markDefs":[],"children":[{"text":"Tune in monthly on ","_key":"9f687175575a","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive","_key":"ef80cdf36b2e"},{"text":" for empowering conversations that will help you build a fulfilling career and life! All episodes of The Medical Sisterhood will be available in a video format via HCPLive.com, with audio-only version available via Apple and Spotify.","_key":"2d3c03b80ddf","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"399468556c33"},{"_key":"61bec9e341a9","markDefs":[{"_key":"629061328ce3","nofollow":true,"blank":true,"_type":"link","href":"https://www.linkedin.com/groups/13095556/"}],"children":[{"marks":["629061328ce3","strong"],"text":"Want to join The Medical Sisterhood community? Click here to join our LinkedIn Group!","_key":"bb236d09cbd1","_type":"span"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"8449d2318449","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Editor's note: This summary was created with the help of artificial intelligence.","_key":"28620f8a4b5d"}]}],"title":"The Medical Sisterhood: Men, Medicine, and Their Female Mentors","authorMapping":[{"firstName":"Mona","displayName":"Mona Shahriari, MD, FAAD","_rev":"hkdPnl63Es19oMLWlTEncJ","_type":"author","_id":"c0271bed-fd84-49b6-9126-a82acb3be026","lastName":"Shahriari","_createdAt":"2023-06-19T13:59:49Z","_updatedAt":"2023-06-19T13:59:49Z","url":{"current":"mona-shahriari-md-faad","_type":"slug"}},{"lastName":"Del Rosso","authorType":"expert","_rev":"XE9vnGgPXscpvWVDkxlr69","_id":"89b46644-6ed6-4741-89aa-02b6fc83ce8d","profileImage":{"_type":"mainImage","alt":"James Del Rosso, DO | Credit: American Osteopathic College of Dermatology","asset":{"_ref":"image-c1f6a714cafe164319297ff492194b3a212d4ec2-300x300-jpg","_type":"reference"}},"_updatedAt":"2025-02-17T05:30:02Z","url":{"current":"james-del-rosso-do","_type":"slug"},"firstName":"James","displayName":"James Del Rosso, DO","_createdAt":"2025-02-17T05:27:35Z","_type":"author","biography":[{"style":"normal","_key":"54709e9e3188","markDefs":[],"children":[{"_type":"span","marks":[],"text":"James Q. Del Rosso, DO, is the research director of JDR Dermatology Research and president of the American Acne and Rosacea Society.","_key":"10792e3b65ce"}],"_type":"block"}]}],"summary":"In this episode, James Q. Del Rosso, DO, joins The Medical Sisterhood for a conversation about empowerment and the benefits of female role models.","url":{"current":"the-medical-sisterhood-white-coats-wingmen-how-men-can-uplift-women-in-medicine","_type":"slug"},"_id":"dae00c38-f11a-486f-af2f-7ccb26302816","is_visible":true,"taxonomyMapping":[{"summary":[{"children":[{"_key":"e30bc15db24b0","_type":"span","marks":[],"text":"The Medical Sisterhood, hosted by Mona Shahriari, MD, is a podcast dedicated to empowering female physicians by providing a platform for shared experiences, mentorship, and support. "}],"_type":"block","style":"normal","_key":"a78669bc715f","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Each episode delves into the unique challenges women in medicine face, including work-life balance, leadership roles, and overcoming gender biases. Shahriari aims to inspire women to lead fulfilling professional and personal lives on their own terms through candid discussions and expert interviews. ","_key":"90f155035258"}],"_type":"block","style":"normal","_key":"2431a54f2d0e"},{"_type":"block","style":"normal","_key":"1f13b2b3a394","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Join us monthly on ","_key":"4b8acb1ac453"},{"_type":"span","marks":["em"],"text":"HCPLiv","_key":"1f2d2a33445b"},{"_key":"b45aae9a8881","_type":"span","marks":[],"text":"e as we foster a community where women can uplift and support each other in achieving their goals!"}]}],"isMainTopic":true,"_rev":"d85e4RNWNOToFCQ81qIiB0","usedForRecommendations":false,"video":{"isTaxVideo":false},"_updatedAt":"2025-01-03T18:38:40Z","parent":{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference"},"thumbnail":{"default":true,"_type":"mainImage","asset":{"_ref":"image-9e35d3e96456c41a667432dda69f0394ea353558-8001x4500-jpg","_type":"reference"}},"_createdAt":"2024-09-13T17:07:35Z","name":"The Medical Sisterhood, with Mona Shahriari, MD","_id":"b4e75d36-531d-4379-bd58-ff7f3b5ba3f8","_type":"taxonomy","identifier":"the-medical-sisterhood","videoPlayerConfig":{"brightcoveAccountID":"5436121609001"},"taxonomyArchived":false},{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z"},{"identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"_type":"taxonomy"},{"identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy","name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z"},{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"3b1c50e6e15b"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"c9b6f58fcd46"},{"_type":"span","marks":[],"text":"podcasts page features a feed of medical news and interview podcast series, including DocTalk, Lungcast, Derm Discussions, and Heart Trials.","_key":"fb5df9c2d5d3"}],"_type":"block","style":"normal","_key":"dea2cb0508c7"}],"identifier":"podcasts","_createdAt":"2020-07-08T03:27:37Z","_rev":"AR6qoypNcER7zlbM0q7CE8","_type":"taxonomy","_updatedAt":"2025-01-04T14:41:58Z","name":"Podcasts","_id":"71feb86d-3e1f-46c8-9508-28c43eddc1bc"},{"name":"Dermatology","_id":"topic_dermatology","identifier":"dermatology","perKeywordMapping":["Dermatology","Dermatologic Cancer"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_rev":"uvXJooXtzvjNOyx50DtOz4","_type":"taxonomy","_updatedAt":"2023-03-30T18:37:18Z","summary":[{"style":"normal","_key":"2d374a27e197","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.","_key":"bfe5d86caad9"}],"_type":"block"}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"isMainTopic":false}]},{"taxonomyMapping":[{"_updatedAt":"2024-09-27T20:47:32Z","summary":[{"_key":"05eda7184d6f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d"},{"identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy","name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z"},{"_createdAt":"2020-05-20T18:09:49Z","_rev":"QX7y4QewgOajo2HeiHq5KN","_type":"taxonomy","_id":"topic_chronic-idiopathic-urticaria","_updatedAt":"2021-08-20T00:22:05Z","summary":[{"style":"normal","_key":"31027e2639fb","markDefs":[],"children":[{"text":"The HCPLive chronic idiopathic urticaria page is a comprehensive resource for clinical news and insights on CIU. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for urticaria, and more.","_key":"d1966bbb3a12","_type":"span","marks":[]}],"_type":"block"}],"identifier":"chronic-idiopathic-urticaria","parent":{"_ref":"topic_dermatology","_type":"reference"},"name":"Chronic Idiopathic Urticaria"},{"_type":"taxonomy","_updatedAt":"2023-03-30T18:37:18Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.","_key":"bfe5d86caad9"}],"_type":"block","style":"normal","_key":"2d374a27e197"}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"isMainTopic":false,"name":"Dermatology","_id":"topic_dermatology","identifier":"dermatology","perKeywordMapping":["Dermatology","Dermatologic Cancer"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_rev":"uvXJooXtzvjNOyx50DtOz4"},{"identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block"}],"_type":"taxonomy"},{"_createdAt":"2020-05-20T18:56:26Z","_rev":"YRDSDtoOLfpMnIoh6KhWz6","name":"Conference","_updatedAt":"2021-07-12T14:48:51Z","summary":[{"children":[{"_type":"span","marks":[],"text":"The ","_key":"dbe4363ac45f"},{"marks":["em"],"text":"HCPLive","_key":"1b61fa9e9b1b","_type":"span"},{"text":" conference coverage page features articles, videos, and expert-led live coverage from major medical meetings throughout the year.","_key":"8c9920cfe0ff","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"c3b632cb35f8","markDefs":[]}],"_type":"taxonomy","_id":"6e1a5e9c-c5e9-4d19-b803-e00d93da7863","identifier":"conference"}],"_updatedAt":"2025-02-18T20:29:17Z","body":[{"videoObject":{"videoDescription":" Bernstein discussed recent and upcoming research and management of angioedema in patients with urticaria.","_type":"videoDetails","videoTitle":"Understanding Angioedema in Urticaria, with Jonathan Bernstein, MD","thumbnail":{"_type":"image","asset":{"_ref":"image-5bb317b68d93f495a63b8feaf1065f0d8eb3bf69-1280x720-png","_type":"reference"}},"videoDuration":"PT6M22S"},"_type":"video","caption":"Understanding Angioedema in Urticaria, with Jonathan Bernstein, MD","videoID":"6368840200112","disableAutoPlayVideo":false,"source":"brightcove","_key":"f4c3f3edfe51"},{"children":[{"_type":"span","marks":[],"text":"Angioedema is a complication that has a significant burden on patients with inflammatory skin conditions such as urticaria. While research is ongoing in the field to better treat angioedema, unmet needs in its management remain.","_key":"81af16f23a94"}],"_type":"block","style":"normal","_key":"babea5eb75fc","markDefs":[]},{"style":"normal","_key":"dab10610579e","markDefs":[],"children":[{"text":"Jonathan Bernstein, MD, adjunct professor, University of Cincinnati School of Medicine and past president of the American Academy of Allergy, Asthma, and Immunology (AAAAI) is giving a talk on emerging treatment approaches for angioedema in patients with urticaria at the 2025 AAAAI/World Allergy Organization Joint Congress, February 28-March 3, in San Diego, California.","_key":"7b3a950f9d30","_type":"span","marks":[]}],"_type":"block"},{"markDefs":[],"children":[{"text":"“I think that's really the biggest thing that's confronting us, is to get clinicians understand the spectrum of angioedema and to make sure that they aren't skipping steps and going from inexpensive antihistamines to extremely expensive drugs that are targeted towards hereditary angioedema,” Bernstein told ","_key":"0d796eea6620","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"9367e493bbdd"},{"_type":"span","marks":[],"text":"in an interview.","_key":"688948d96381"}],"_type":"block","style":"normal","_key":"daf01860f92f"},{"_key":"08e9b161c87e","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"HCPLive","_key":"154830434c58"},{"_key":"ef492399202b","_type":"span","marks":[],"text":" spoke with Bernstein to learn more about unmet needs in patients with angioedema and urticaria, including making appropriate decisions and implementing physician education to improve this. He also discussed progress in research in the space, and current research adding to the field’s understanding of the disease, including mast cells mechanisms."}],"_type":"block","style":"normal"},{"_key":"fbae2aa28c7b","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“We're learning more about mast cell biology and activation, which is really important in terms of drug development. So, we'll see how everything plays out in terms of, you know, looking at these more difficult to treat patients with chronic urticaria, and how these drugs work, but I think that we're going to see a significant benefit for patients who don't respond well to antihistamines or omalizumab in responding to some of these other alternative, mechanistic, mechanistically driven therapies,” Bernstein said.","_key":"19f7eeeb5004"}],"_type":"block","style":"normal"},{"_type":"block","style":"h6","_key":"7270b5425d8b","markDefs":[],"children":[{"text":"REFERENCE","_key":"5fed8431c52c","_type":"span","marks":[]}]},{"_type":"block","style":"h6","_key":"ef790eafbd5e","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Bernstein J. Emerging Treatment Approaches to Hives, Itch, and Angioedema. Presented at: 2025 AAAAI/WAO Joint Congress, February 28-March 3.","_key":"e4efe27e9226"}]}],"_type":"article","summary":"Bernstein discussed recent and upcoming research and management of angioedema in patients with urticaria.","articleType":"Commentary","_createdAt":"2025-02-14T23:50:13Z","_rev":"Fd1jDX9jbPHQLM4ybiO4ge","_id":"4815377e-7679-4ff4-81fa-a8da39613541","thumbnail":{"asset":{"_rev":"PLEWUyW89561a5CWnhDCeA","_type":"sanity.imageAsset","mimeType":"image/jpeg","assetId":"c366f244dfddef56b7d88602ded0c0ddb7ee3acf","_id":"image-c366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355-jpg","originalFilename":"Jonathan-Bernstein-Clinic.jpeg","metadata":{"blurHash":"eADb{Hx]0Kt7}[8wV@.9jYIABWWC+tofkrEgjZ-UNGM{WAoft7ofNG","_type":"sanity.imageMetadata","palette":{"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":7.52,"background":"#9d6652"},"_type":"sanity.imagePalette","darkMuted":{"background":"#453636","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.99},"muted":{"title":"#fff","population":7.52,"background":"#9d6652","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightVibrant":{"foreground":"#fff","title":"#fff","population":5.59,"background":"#c0836d","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.02,"background":"#4d2f22"},"lightMuted":{"background":"#c2a4a1","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.07},"vibrant":{"background":"#b46c4c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.03}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":355,"aspectRatio":1,"height":355},"isOpaque":true},"sha1hash":"c366f244dfddef56b7d88602ded0c0ddb7ee3acf","path":"images/0vv8moc6/hcplive/c366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg","_createdAt":"2024-02-27T05:40:15Z","_updatedAt":"2024-02-27T05:40:15Z","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/c366f244dfddef56b7d88602ded0c0ddb7ee3acf-355x355.jpg","size":19423,"extension":"jpg","uploadId":"Mm4vLGGG9CmdNueooy1zv0g2WVHaLPdy"}},"documentGroup":{"_ref":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_type":"reference"},"url":{"current":"understanding-angioedema-urticaria-bernstein","_type":"slug"},"authorMapping":[{"firstName":"Victoria","lastName":"Johnson","_rev":"R5Nwo2wgBUbo1xFZSWuqlM","_id":"d4c32d40-a161-4f01-8151-702eff7a6e75","url":{"current":"victoria-johnson","_type":"slug"},"displayName":"Victoria Johnson","_createdAt":"2020-12-10T20:09:41Z","_type":"author","biography":[{"_key":"bf207805c002","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Victoria Johnson joined the MJH Life Sciences in 2020 and has written for NeurologyLive, CGTLive, and now HCPLive. You can reach her at vjohnson@mjhlifesciences.com","_key":"69caae9c35c7"}],"_type":"block","style":"normal"}],"_updatedAt":"2024-09-16T22:30:31Z"},{"lastName":"Bernstein, MD","_rev":"ivaRGNxFBepXyTXsu4gtjZ","_updatedAt":"2025-02-18T20:29:15Z","firstName":"Jonathan","authorType":"expert","displayName":"Jonathan Bernstein, MD","_createdAt":"2025-02-18T20:29:15Z","_type":"author","_id":"b5f1965d-533b-4b1f-bcb4-b6b4624385b5","url":{"current":"jonathan-bernstein-md","_type":"slug"}}],"ExcludeFromPubMedXML":false,"published":"2025-02-15T00:00:33.992Z","documentGroupMapping":[{"_key":"f2cffe2c862c","_ref":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_type":"reference"}],"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"is_visible":true,"title":"Understanding Angioedema in Urticaria, with Jonathan Bernstein, MD","link":"/view/understanding-angioedema-urticaria-bernstein"},{"published":"2025-02-14T11:00:00.000Z","contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"_createdAt":"2025-02-14T03:10:03Z","ExcludeFromPubMedXML":false,"body":[{"videoObject":{"_type":"videoDetails","videoTitle":"Identifying B-cell Depleting Agents for Lupus Nephritis, with Richard Furie, MD","thumbnail":{"_type":"image","asset":{"_ref":"image-5fb7ce0c5a7ab2a970e70f7cb207ca06be689f1c-1280x720-jpg","_type":"reference"}},"videoDuration":"PT5M30S","videoDescription":"Furie discussed his experiences in evaluating therapies such as rituximab and now obinutuzumab for lupus nephritis."},"_type":"video","caption":"Identifying B-cell Depleting Agents for Lupus Nephritis, with Richard Furie, MD","videoID":"6368796477112","disableAutoPlayVideo":false,"source":"brightcove","_key":"4722770b2565"},{"_key":"bd8fa5208158","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Obinutuzumab (Gazya/Gazyvaro) was found to be superior to standard of care therapy alone for achieving a complete renal response in patients with active lupus nephritis, according to results from the phase 3 REGENCY trial.","_key":"b170e564e065"}],"_type":"block","style":"normal"},{"children":[{"_key":"a6e74d1990f7","_type":"span","marks":[],"text":"REGENCY evaluated obinutuzumab for efficacy in patients with active lupus nephritis with a primary endpoint of complete renal response compared with placebo. Investigators found that obinutuzumab was associated with a statistically significant and clinically meaningful improvement in complete renal response, with 46.4% achieving complete renal response at 76 weeks compared to just 33.1% of people treated with standard therapy alone (adjusted difference, 13.4%; 95% CI, 2.0 to 24.8; "},{"text":"P","_key":"068dcb41abcc","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":" = .0232). Investigators pointed out there were no unexpected safety signals identified in the trial, but more serious adverse events, mainly infections and events related to coronavirus disease 2019, occurred among the obinutuzumab group.","_key":"b78598191bfa"}],"_type":"block","style":"normal","_key":"ee5d45edc120","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"cc17e0237f03"},{"marks":[],"text":"spoke with primary investigator Richard Furie, MD, the Marilyn and Barry Rubenstein Chair in Rheumatology and Chief of the Division of Rheumatology at Northwell Health, to learn more about obinutuzumab’s use for treating lupus nephritis and other forms of lupus. He shared his experience investigating B-cell depleting agents for lupus, beginning with rituximab and continuing to obinutuzumab.","_key":"fc07dbba2cdf","_type":"span"}],"_type":"block","style":"normal","_key":"b0118870ccee"},{"_key":"59acbcfcb397","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“I first heard about obinutuzumab probably some 10 years ago, and it was approved for chronic lymphocytic leukemia in 2013, so they had safety data. And the question was, should we do another study, much like LUNAR the rituximab lupus nephritis trial, but with a more potent antibody? And I said, sure, let's do a study. And the condensed version of that whole story with the NOBILITY trial in lupus nephritis… was that it was a positive study,” Furie said.","_key":"2e41707c39b5"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"marks":[],"text":"REFERENCE","_key":"1f5a0752f8a4","_type":"span"}],"_type":"block","style":"h6","_key":"8d74c81adf34"},{"style":"h6","_key":"5be9e847873e","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Furie RA, Rovin BH, Garg JP. Efficacy and Safety of Obinutuzumab in Active Lupus Nephritis. ","_key":"cb61ad182c29"},{"_type":"span","marks":["em"],"text":"New England Journal of Medicine","_key":"15e851f51d38"},{"text":". Published online February 7, 2025. doi:10.1056/NEJMoa2410965","_key":"294f0e56467d","_type":"span","marks":[]}],"_type":"block"}],"title":"Identifying B-cell Depleting Agents for Lupus Nephritis, with Richard Furie, MD","articleType":"Commentary","_rev":"nk0hGN8AuHdSYpy8At16cN","_id":"b3ff930e-4d4b-4d64-b1bd-e4fd7c510853","_type":"article","url":{"current":"identifying-b-cell-depleting-agents-lupus-nephritis-furie","_type":"slug"},"summary":"Furie discussed his experiences in evaluating therapies such as rituximab and now obinutuzumab for lupus nephritis.","taxonomyMapping":[{"_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"_key":"05eda7184d6f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy"},{"_updatedAt":"2023-01-19T19:43:30Z","parent":{"_ref":"topic_rheumatology","_type":"reference"},"_type":"taxonomy","name":"Lupus","usedForRecommendations":false,"identifier":"lupus","_createdAt":"2022-12-12T23:19:17Z","_rev":"ATgVt3YpEt10cAklztiqaQ","_id":"39ebe0b3-bfce-469d-bf9e-f6c9cef44ab7"},{"perKeywordMapping":["Rheumatology","Internal Medicine"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_type":"taxonomy","name":"Rheumatology","_id":"topic_rheumatology","_updatedAt":"2024-06-19T19:50:34Z","identifier":"rheumatology","parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"_rev":"PzUQ1fFJ07T42BPFoevvTs","summary":[{"asset":{"_ref":"image-b1d0e443e67130c65adb7d222b248f0971f081cc-2054x1072-png","_type":"reference"},"widthP":25,"disableTextWrap":false,"disableLightBox":true,"_type":"figure","_key":"d59085cf52a8","alignment":"left"},{"style":"normal","_key":"3cdbeac17304","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"414c07d22566"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"4ae0976c8834"},{"_type":"span","marks":[],"text":"Rheumatology condition center page is a comprehensive resource for clinical news and insights on rheumatologic disease. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for arthritis, gout, nr-AxSpA, and more.","_key":"01a0e6030faf"}],"_type":"block"}]},{"identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}]}],"_type":"taxonomy"}],"_updatedAt":"2025-02-14T03:10:03Z","thumbnail":{"asset":{"assetId":"52bc53885be619607cc0bbb906f3aee4913f5951","_type":"sanity.imageAsset","mimeType":"image/jpeg","path":"images/0vv8moc6/hcplive/52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg","_updatedAt":"2023-02-21T23:10:08Z","size":3972,"_id":"image-52bc53885be619607cc0bbb906f3aee4913f5951-120x129-jpg","metadata":{"isOpaque":true,"_type":"sanity.imageMetadata","palette":{"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":10.5,"background":"#ce9483"},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.94,"background":"#50352a"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":9.65,"background":"#94665a"},"lightVibrant":{"background":"#edb59f","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":1.12},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.74,"background":"#33160f"},"lightMuted":{"population":0.85,"background":"#d9bcb2","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"population":10.5,"background":"#ce9483","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":120,"aspectRatio":0.9302325581395349,"height":129}},"uploadId":"bjKW50R4JXdeMQIW52SD3A0V4GoGXUgb","_rev":"CDXqxqJ4c7akEZTOZfdP7q","sha1hash":"52bc53885be619607cc0bbb906f3aee4913f5951","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/52bc53885be619607cc0bbb906f3aee4913f5951-120x129.jpg","originalFilename":"Richard%20Alan%20Furie,%20MD.jpg","extension":"jpg","_createdAt":"2023-02-21T23:10:07Z"}},"is_visible":true,"authorMapping":[{"displayName":"Victoria Johnson","_createdAt":"2020-12-10T20:09:41Z","_type":"author","biography":[{"_key":"bf207805c002","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Victoria Johnson joined the MJH Life Sciences in 2020 and has written for NeurologyLive, CGTLive, and now HCPLive. You can reach her at vjohnson@mjhlifesciences.com","_key":"69caae9c35c7"}],"_type":"block","style":"normal"}],"_updatedAt":"2024-09-16T22:30:31Z","firstName":"Victoria","lastName":"Johnson","_rev":"R5Nwo2wgBUbo1xFZSWuqlM","_id":"d4c32d40-a161-4f01-8151-702eff7a6e75","url":{"current":"victoria-johnson","_type":"slug"}},{"_rev":"nk0hGN8AuHdSYpy8AshYbJ","_id":"15650ff6-571a-46a6-8e38-7739ff363836","url":{"current":"richard-furie-md","_type":"slug"},"lastName":"Furie, MD","displayName":"Richard Furie, MD","_createdAt":"2025-02-14T02:50:30Z","_type":"author","_updatedAt":"2025-02-14T02:50:30Z","firstName":"Richard","authorType":"expert"}],"link":"/view/identifying-b-cell-depleting-agents-lupus-nephritis-furie"},{"authorMapping":[{"displayName":"Abigail Brooks, MA","_type":"author","profileImage":{"_type":"mainImage","asset":{"_ref":"image-93bd0088a30dd94cde45491e60398457d8055321-1928x2700-jpg","_type":"reference"}},"url":{"current":"abigail-brooks","_type":"slug"},"lastName":"Brooks","_createdAt":"2023-08-16T21:01:55Z","_rev":"sXRLufgca24g5WFAwOy51f","_id":"a4f8c360-5ae6-48cb-99c0-286a6b76f037","biography":[{"_key":"ad4ff818a6d3","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Abigail Brooks is an assistant editor for ","_key":"1d7645ea6da80"},{"_type":"span","marks":["em"],"text":"HCPLive. ","_key":"1d7645ea6da81"},{"_type":"span","marks":[],"text":"She joined MJH Life Sciences in August 2023 shortly after graduating from Monmouth University where she earned her BA in Communication with a concentration in Public Relations/Journalism and later an MA in Interactive Digital Media. She enjoys traveling, running, and reading books. She can be reached at abrooks@mjhlifesciences.com.","_key":"1d7645ea6da82"}],"_type":"block","style":"normal"}],"_updatedAt":"2023-08-16T21:01:55Z","firstName":"Abigail"},{"displayName":"Brian Lee, MD","_createdAt":"2025-02-13T20:16:30Z","_id":"8cc78828-1ac6-4d38-849e-9c7f4285215b","url":{"_type":"slug","current":"brian-lee-md"},"lastName":"Lee","authorType":"expert","_rev":"XE9vnGgPXscpvWVDknlN0z","_type":"author","biography":[{"style":"normal","_key":"61278df39b04","markDefs":[],"children":[{"marks":[],"text":"Brian Lee, MD, is a hepatologist and liver transplant specialist with Keck School of Medicine of USC.","_key":"0f152b7aba30","_type":"span"}],"_type":"block"}],"profileImage":{"alt":"Brian Lee, MD | Credit: American Association for the Study of Liver Diseases","asset":{"_ref":"image-7e31af7c2dce356d5325b0914669c20e69dda682-744x744-png","_type":"reference"},"_type":"mainImage"},"_updatedAt":"2025-02-13T20:18:38Z","firstName":"Brian"}],"is_visible":true,"url":{"current":"improving-fibrosis-risk-stratification-metald-brian-lee-md","_type":"slug"},"_id":"8e76d3de-0dd7-4406-8c98-12eeed2694dc","_updatedAt":"2025-02-14T21:43:04Z","taxonomyMapping":[{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z"},{"name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[]}],"_type":"taxonomy","identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0"},{"isMainTopic":true,"_createdAt":"2023-04-25T23:31:12Z","_type":"taxonomy","_id":"44abda14-7b81-4a4f-ac34-a5e848aa62b2","identifier":"hepatology","parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"_rev":"cOrVoLHD1qT5y0raOasIM3","name":"Hepatology","usedForRecommendations":false,"_updatedAt":"2023-04-25T23:31:20Z"},{"summary":[{"_type":"block","style":"normal","_key":"a9aa56b4170f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive MASH \u0026 MASLD page is a comprehensive resource for clinical news and insights on metabolic dysfunction-associated steatotic liver disease and steatohepatitis. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for fatty liver disease, steatohepatitis, and more.","_key":"a026eabb7fb50"}]}],"_createdAt":"2024-02-15T17:57:46Z","_type":"taxonomy","name":"MASH / MASLD","usedForRecommendations":false,"_id":"82d0e148-23b4-480a-b0a5-f5bddfaaa00f","identifier":"mash-masld","parent":{"_type":"reference","_ref":"44abda14-7b81-4a4f-ac34-a5e848aa62b2"},"_rev":"u7KWSLocEROtTPtelfBFOe","video":{"isTaxVideo":false},"_updatedAt":"2024-02-15T17:57:46Z"},{"_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy","name":"Videos"}],"_type":"article","_rev":"5MymcCPmeJiqJMv8mcQo5v","ExcludeFromPubMedXML":false,"published":"2025-02-14T00:00:56.281Z","body":[{"source":"brightcove","_key":"bcc34ec1e919","videoObject":{"thumbnail":{"_type":"image","asset":{"_type":"reference","_ref":"image-56921c65a7d5d6d06f4bd3d3772dea5dad0a8cbf-1010x564-png"}},"videoDuration":"PT8M20S","videoDescription":"Improving Fibrosis Risk Stratification in MetALD, with Brian Lee, MD","_type":"videoDetails","videoTitle":"Improving Fibrosis Risk Stratification in MetALD, with Brian Lee, MD"},"_type":"video","videoID":"6368780975112","disableAutoPlayVideo":true},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"In 2023, A modified Delphi process led by the American Association for the Study of Liver Disease, the European Association for the Study of the Liver, and the Latin American Association for the Study of the Liver yielded new liver disease nomenclature to address concerns regarding the terminology “nonalcoholic fatty liver disease” and “metabolic-associated fatty liver disease.”","_key":"7b57dede8358"}],"_type":"block","style":"normal","_key":"0920cfa19f19"},{"_key":"9d8a25f35935","markDefs":[{"_key":"01278fa9fd83","nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/clinical/mash-masld"}],"children":[{"_type":"span","marks":[],"text":"The revised nomenclature introduced the term ","_key":"c10dcd45d578"},{"text":"“metabolic dysfunction-associated steatotic liver disease” (MASLD)","_key":"21d2c2dd89c4","_type":"span","marks":["01278fa9fd83"]},{"_type":"span","marks":[],"text":" to describe patients who have hepatic steatosis and ≥ 1 of 5 cardiometabolic risk factors (CRMF). Additionally, the updated nomenclature added a new classification, MetALD, to represent a separate group of patients with MASLD who consume alcohol at a rate of 140–350 g/wk for females and 210–420 g/wk for males.","_key":"fcd0c4adc33e"},{"_key":"5ffd214d26f3","_type":"span","marks":["sup"],"text":"2"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":[],"text":"“There have been several questions that have come up because of the nomenclature, but one of the controversies was whether MetALD should be defined by just 1 metabolic risk factor, Brian Lee, MD, a hepatologist and liver transplant specialist with Keck Medicine of USC, explained to ","_key":"da53ba778aa1"},{"text":"HCPLive","_key":"1626a31911a1","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":". “We know that alcohol can actually cause metabolic risk factors. So if you have just 1 and increased alcohol intake, is it truly a distinct disease?”","_key":"90a2e024296d"}],"_type":"block","style":"normal","_key":"015f2f6fa8e1","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"Lee noted this was one of several questions he and a group of colleagues sought to answer in their recent analysis of NHANES data assessing FIB-4 scores in adults ≥ 20 years of age with complete alcohol and CMRF status.","_key":"b9c29364f15e"},{"_key":"686fcf674ccb","_type":"span","marks":["sup"],"text":"2"}],"_type":"block","style":"normal","_key":"dbcd40df2666","markDefs":[]},{"_key":"f19741395625","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Results showed the prevalence of FIB-4 \u003e2.67 among individuals with and without increased alcohol use was higher at each quantity of CMRFs and with each incremental CMRF:","_key":"6803b1d0aa22"}],"_type":"block","style":"normal"},{"children":[{"text":"0 CRMFs: (2.3%; 95% CI, 1.0-5.0% vs 0.7%; 95% CI, 0.5-0.9%)","_key":"226b48d4f0fe","_type":"span","marks":[]}],"level":1,"_type":"block","style":"normal","_key":"c7b4d417d8ff","listItem":"bullet","markDefs":[]},{"listItem":"bullet","markDefs":[],"children":[{"marks":[],"text":"1 CRMF: (3.0%; 95% CI, 1.6-5.6% vs 1.7%; 95% CI, 1.4-2.1%)","_key":"e92f106e6fc4","_type":"span"}],"level":1,"_type":"block","style":"normal","_key":"12afce93e6b8"},{"level":1,"_type":"block","style":"normal","_key":"da43b57cffe9","listItem":"bullet","markDefs":[],"children":[{"_key":"cb6894902601","_type":"span","marks":[],"text":"2 CRMFs: (3.3%; 95% CI, 2.1-5.1% vs 2.1%; 95% CI, 1.8-2.4%)"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"3 CRMFs: (5.9%; 95% CI, 3.5-9.6% vs 2.5%; 95% CI, 2.1-2.9%)","_key":"6c8f8880c931"}],"level":1,"_type":"block","style":"normal","_key":"c3e9a6630470","listItem":"bullet"},{"children":[{"_type":"span","marks":[],"text":"4 or 5 CRMFs (6.1%; 95% CI, 3.3-9.7% vs 4.0%; 95% CI, 3.5-4.5%)","_key":"682436c56d13"}],"level":1,"_type":"block","style":"normal","_key":"24725abe9b37","listItem":"bullet","markDefs":[]},{"_type":"block","style":"normal","_key":"439eb9904775","markDefs":[],"children":[{"marks":[],"text":"Among individuals with increased alcohol, in multivariable logistic regression analysis, 3 (adjusted odds ratio [aOR], 2.57; 95% CI, 0.93-7.08) and 4 or 5 (aOR, 2.64; 95% CI, 1.05-6.67) CMRFs were associated with 2-fold greater odds of high FIB-4 versus 0 CRMFs, but not 1 (aOR, 1.24; 95% CI, 0.41-3.69) or 2 (aOR, 1.39; 95% CI, 0.56-3.50) CMRFs.","_key":"dab514a8feaf","_type":"span"},{"_type":"span","marks":["sup"],"text":"2","_key":"71575bbf6224"}]},{"_key":"a5451eb86c61","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“The cutoff where you have a different risk of liver fibrosis is not with 1 cardiometabolic risk factor, but it's really with 3 or more,” Lee said. “So, the take-home message here is that we should be classifying MetALD with not just 1, but really 3 or more cardiometabolic risk factors, and maybe having this higher threshold for cut-off would better differentiate the patient populations in steatotic liver disease.”","_key":"ee1cbe0c561c"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Editors’ note: Lee has no relevant disclosures.","_key":"03815553f2e9"}],"_type":"block","style":"normal","_key":"3ca49545b325"},{"children":[{"marks":["strong"],"text":"References","_key":"0d4bf518f904","_type":"span"}],"_type":"block","style":"h6","_key":"a35b2d2fc796","markDefs":[]},{"_type":"block","style":"h6","_key":"b6f97f299f35","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":["sup"],"text":"Brooks A. From NAFLD to MASLD: 2023 Brings New Liver Disease Nomenclature. ","_key":"70b8bf823fb7"},{"_type":"span","marks":["em","sup"],"text":"HCPLive","_key":"c40525de2382"},{"_type":"span","marks":["sup"],"text":". December 13, 2023. Accessed February 13, 2025. https://www.hcplive.com/view/from-nafld-to-masld-2023-new-liver-disease-nomenclature","_key":"6d4d58debcdf"}],"level":1},{"style":"h6","_key":"690c456e1cf2","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":["sup"],"text":"Lee BP, Molina J, Kim S, et al. Association of Alcohol and Incremental Cardiometabolic Risk Factors with Liver Disease: A National Cross-Sectional Study. ","_key":"c693f699f5ce"},{"_type":"span","marks":["em","sup"],"text":"Clin Gastroenterol Hepatol","_key":"03971cd73cd8"},{"_type":"span","marks":["sup"],"text":". doi:10.1016/j.cgh.2025.01.003","_key":"1df3941d59c6"}],"level":1,"_type":"block"}],"title":"Improving Fibrosis Risk Stratification in MetALD, with Brian Lee, MD","_createdAt":"2025-02-13T20:15:27Z","thumbnail":{"asset":{"mimeType":"image/png","assetId":"7e31af7c2dce356d5325b0914669c20e69dda682","originalFilename":"Screenshot 2025-02-13 at 3.18.07 PM.png","extension":"png","uploadId":"RSatoW59ECPJ3VApLETIDxGEYORCOcu2","_rev":"5MymcCPmeJiqJMv8mYw5Gr","size":603142,"_id":"image-7e31af7c2dce356d5325b0914669c20e69dda682-744x744-png","_type":"sanity.imageAsset","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png","path":"images/0vv8moc6/hcplive/7e31af7c2dce356d5325b0914669c20e69dda682-744x744.png","metadata":{"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":744,"aspectRatio":1,"height":744},"isOpaque":true,"blurHash":"e8AvRc~A020M9aIVxa%2NGR-0#E2$%-p-UIpWrxZs9R-I=I:sm-oxZ","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"population":0.97,"background":"#715437","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"background":"#ab8162","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.74},"lightVibrant":{"background":"#d6b494","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0},"darkVibrant":{"population":0.04,"background":"#541909","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"background":"#b58f75","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":1.77},"vibrant":{"background":"#8c5434","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.03},"dominant":{"foreground":"#fff","title":"#fff","population":6.74,"background":"#ab8162","_type":"sanity.imagePaletteSwatch"}},"hasAlpha":true},"sha1hash":"7e31af7c2dce356d5325b0914669c20e69dda682","_createdAt":"2025-02-13T20:18:25Z","_updatedAt":"2025-02-13T20:18:25Z"}},"contentCategory":{"name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory"},"articleType":"News","summary":"Lee explains study findings suggesting MetALD classification should be based on ≥ 3 cardiometabolic risk factors rather than just alcohol intake.","link":"/view/improving-fibrosis-risk-stratification-metald-brian-lee-md"},{"body":[{"_key":"c1b1f8c7d308","videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-bd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207-jpg","_type":"reference"}},"videoDuration":"12M02S","videoDescription":"Transformations in Aortic Disease Management with Mehrdad Ghoreishi, MD","_type":"videoDetails","videoTitle":"Transformations in Aortic Disease Management with Mehrdad Ghoreishi, MD"},"_type":"video","videoID":"6368774056112","disableAutoPlayVideo":false,"source":"brightcove"},{"markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/sap-partner/baptist-health-south-florida","_key":"b67e1ff834c7"},{"blank":true,"_type":"link","href":"https://www.hcplive.com/clinical/structural-heart-disease","_key":"869ad0162cdc"}],"children":[{"_type":"span","marks":[],"text":"In a recent interview with ","_key":"f44b28948089"},{"marks":["em"],"text":"HCPLive","_key":"dc2e59cb3e2d","_type":"span"},{"_type":"span","marks":[],"text":", Mehrdad Ghoreishi, MD, the co-director of aortic surgery and medical director of cardiac surgery research at ","_key":"898dbae16501"},{"_type":"span","marks":["b67e1ff834c7"],"text":"Baptist Health Miami Cardiac \u0026 Vascular Institute","_key":"30de475f51f9"},{"_key":"2d8727d88739","_type":"span","marks":[],"text":", discussed the evolving landscape of "},{"_type":"span","marks":["869ad0162cdc"],"text":"aortic disease","_key":"1b26d15aefe0"},{"_type":"span","marks":[],"text":" treatment, highlighting the advantages of minimally invasive endovascular techniques compared with traditional open-heart surgery.","_key":"652e510efccf"}],"_type":"block","style":"normal","_key":"77ab50152120"},{"style":"normal","_key":"8240d6b52a52","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Ghoreishi recently presented a session entitled “The Next Frontier: Ascending Aorta and Aortic Valve Therapy” at the International Symposium on Endovascular Therapy (iSET) 2025 in Hollywood, Florida.","_key":"4b7c7b6475f7"}],"_type":"block"},{"_key":"d4419022d2a1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"While open surgery remains the gold standard for aortic root, ascending aorta, and aortic arch diseases, endovascular approaches offer viable alternatives for patients unable to tolerate major surgery. Ghoreishi detailed the current availability of US Food and Drug Administration (FDA)-approved devices for the descending thoracic and abdominal aorta and the ongoing trials for ascending aorta and aortic arch interventions.","_key":"7f46a5a0e0a6"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":[],"text":"Ghoreishi also underscored the importance of multidisciplinary collaboration in aortic care, emphasizing the role of cardiac surgeons, vascular specialists, interventional radiologists, and cardiologists in optimizing treatment strategies. This team-based approach not only improves surgical planning but also ensures comprehensive follow-up care, enhancing patient outcomes.","_key":"bd1535c84f3d"}],"_type":"block","style":"normal","_key":"a545599dee59","markDefs":[]},{"markDefs":[],"children":[{"_key":"bab05b186fc1","_type":"span","marks":[],"text":"Looking ahead, Ghoreishi shared excitement for upcoming advancements in both open and endovascular procedures, including novel stent graft technologies for the aortic arch and ascending aorta. He highlighted the potential of endovascular solutions for high-risk patients, particularly in the context of Type A aortic dissections, where minimally invasive techniques could serve as a bridge to definitive treatment. As the field progresses, he expressed anticipation for significant innovations over the next five years that will expand the scope of endovascular therapy, ultimately transforming the management of complex aortic disease."}],"_type":"block","style":"normal","_key":"27c964cbd627"},{"style":"normal","_key":"d26d4cd75492","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Disclosures: Ghoreishi reports no relevant disclosures.","_key":"c98fdaf09215"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"References","_key":"31d4699108f6"}],"_type":"block","style":"normal","_key":"f8b56ca80a2f"},{"markDefs":[],"children":[{"marks":[],"text":"Ghoreishi M. The Next Frontier: Ascending Aorta and Aortic Valve Therapy. Presented at the International Symposium on Endovascular Therapy (iSET) 2025. Hollywood, Florida. February 2–5, 2025.","_key":"0f792ce472c5","_type":"span"}],"_type":"block","style":"h6","_key":"fbc3eefdc4ef"}],"documentGroupMapping":[{"_type":"reference","_key":"bf86a3c85a40","_ref":"b339b6f8-c346-440b-b373-bfbb7e99cbad"}],"summary":"Mehrdad Ghoreishi, MD explores the latest advances in aortic disease treatment and the role of minimally invasive techniques.\n\n\n\n\n\n\n\n","taxonomyMapping":[{"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"_type":"block","style":"normal","_key":"05eda7184d6f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}]}]},{"_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"_type":"taxonomy","identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532"},{"identifier":"sap-partner","_createdAt":"2020-07-08T18:40:51Z","_rev":"WUaJI1B1cH9LUFbSaSy8FI","_type":"taxonomy","name":"Strategic Alliance Partnership","_id":"3ebb112d-048c-4b3f-bc4d-ebc65ded4ecd","_updatedAt":"2021-10-20T12:03:34Z"},{"name":"Cardiology","_id":"topic_cardiology","_updatedAt":"2023-07-26T18:45:42Z","summary":[{"widthP":25,"disableTextWrap":false,"disableLightBox":true,"_type":"figure","_key":"fe5b40a28a99","alignment":"left","asset":{"_type":"reference","_ref":"image-f9d81b0dd9840678e0ef4dee2aef4863331435b9-2054x1072-png"}},{"_type":"block","style":"normal","_key":"6b7c2d87fa28","markDefs":[],"children":[{"text":"The ","_key":"b769e95c3046","_type":"span","marks":[]},{"_key":"82f5929c2112","_type":"span","marks":["em"],"text":"HCPLive "},{"_type":"span","marks":[],"text":"Cardiology condition center page is a comprehensive resource for clinical news and insights on cardiovascular and cardiometabolic diseases. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for heart disease and cardiovascular events, as well as associated diabetes, renal failure, and more...","_key":"c3782f61ff66"}]}],"perKeywordMapping":["Cardiology"],"_rev":"DgKH9SB1SUwz1DVR8Lastp","identifier":"cardiology","parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_type":"taxonomy"},{"identifier":"structural-heart-disease","_createdAt":"2022-12-12T23:17:04Z","_rev":"IutR9UXsebAwrWt4UoW6Iq","_type":"taxonomy","usedForRecommendations":false,"_id":"edd2ed98-277d-47c8-9046-d6d32a1efdd7","_updatedAt":"2022-12-12T23:17:04Z","parent":{"_ref":"topic_cardiology","_type":"reference"},"name":"Structural Heart Disease"},{"_id":"2f7bbeb0-5cf9-4915-b101-1154d1b62f87","_updatedAt":"2022-12-12T23:22:54Z","parent":{"_ref":"topic_cardiology","_type":"reference"},"_rev":"6HtI1uZEH7uigSfqWIZMjP","usedForRecommendations":false,"identifier":"dyslipidemia","_createdAt":"2022-12-12T23:22:54Z","_type":"taxonomy","name":"Dyslipidemia"}],"url":{"current":"transformations-in-aortic-disease-management-with-mehrdad-ghoreishi-md","_type":"slug"},"ExcludeFromPubMedXML":false,"published":"2025-02-13T23:00:34.111Z","_updatedAt":"2025-02-13T23:00:04Z","_rev":"5MymcCPmeJiqJMv8mZH6g9","title":"Transformations in Aortic Disease Management with Mehrdad Ghoreishi, MD","link":"/view/transformations-in-aortic-disease-management-with-mehrdad-ghoreishi-md","_type":"article","_id":"ea2f7575-ec19-477d-b64d-82e2763ddbe9","is_visible":true,"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"authorMapping":[{"firstName":"Mehrdad","authorType":"expert","displayName":"Mehrdad Ghoreishi, MD","_createdAt":"2025-02-13T18:38:49Z","_rev":"XE9vnGgPXscpvWVDkneYPx","biography":[{"markDefs":[],"children":[{"text":"Mehrdad Ghoreishi, MD, is a board-certified cardiothoracic surgeon; he is the co-director of aortic surgery and medical director of cardiac surgery research at Baptist Health Miami Cardiac \u0026 Vascular Institute.","_key":"09e62adc0211","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"12790a4e254b"}],"_updatedAt":"2025-02-13T18:39:59Z","lastName":"Ghoreishi","_type":"author","_id":"1ebd6018-238e-4606-9ead-f37453e12110","profileImage":{"_type":"mainImage","alt":"Mehrdad Ghoreishi, MD | Image Credit: Baptist Health South Florida","asset":{"_ref":"image-bd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207-jpg","_type":"reference"}},"url":{"current":"mehrdad-ghoreishi-md","_type":"slug"}},{"authorType":"author","displayName":"Connor Iapoce","_createdAt":"2021-04-06T14:07:28Z","_rev":"lMqTJ7iiwxFTeHbLVhHzE4","_type":"author","firstName":"Connor","lastName":"Iapoce","_id":"976f58a6-1439-429f-a1ac-5b1bc00855ef","biography":[{"_type":"block","style":"normal","_key":"599533f3f0aa","markDefs":[],"children":[{"text":"Connor Iapoce is the assistant managing editor for ","_key":"f2f59465653b","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"HCPLive, ","_key":"c19214c63e58"},{"_type":"span","marks":[],"text":"after","_key":"d7fed3c60b95"},{"_key":"0aefa727bc2b","_type":"span","marks":["em"],"text":" "},{"_type":"span","marks":[],"text":"joining the MJH Life Sciences team in April 2021. He graduated from The College of New Jersey with a degree in Journalism and Professional Writing. He enjoys listening to records, going to the movies, and playing with his cat, Squish. You can reach him at ","_key":"64fc9d50c821"},{"_type":"span","marks":["underline"],"text":"ciapoce@mjhlifesciences.com","_key":"303c2d464c84"},{"_type":"span","marks":[],"text":".","_key":"3e46e883cc67"}]}],"_updatedAt":"2025-01-13T19:54:59Z","url":{"current":"connor-iapoce","_type":"slug"}}],"thumbnail":{"asset":{"extension":"jpg","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/bd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg","path":"images/0vv8moc6/hcplive/bd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207.jpg","assetId":"bd67d08be664e11a410e55c5e4dd5553ee45f0c1","_updatedAt":"2025-02-13T18:39:47Z","metadata":{"palette":{"_type":"sanity.imagePalette","darkMuted":{"population":0.01,"background":"#2c3c57","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.32,"background":"#6c7a9d"},"lightVibrant":{"population":0,"background":"#eebc8a","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"darkVibrant":{"foreground":"#fff","title":"#fff","population":0.01,"background":"#1c1004","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"title":"#fff","population":0.51,"background":"#a9b6d0","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"foreground":"#fff","title":"#fff","population":0,"background":"#df7f1f","_type":"sanity.imagePaletteSwatch"},"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.32,"background":"#6c7a9d"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1179,"aspectRatio":0.9768019884009942,"height":1207},"isOpaque":true,"blurHash":"eBB{}-%MEM9Z=|~CadJCkrRP4-WB%2s:M{ElkDwHnNo~S4RjxZxuR+","_type":"sanity.imageMetadata"},"_rev":"XE9vnGgPXscpvWVDkneUmf","_type":"sanity.imageAsset","mimeType":"image/jpeg","sha1hash":"bd67d08be664e11a410e55c5e4dd5553ee45f0c1","_createdAt":"2025-02-13T18:39:47Z","_id":"image-bd67d08be664e11a410e55c5e4dd5553ee45f0c1-1179x1207-jpg","uploadId":"CSPnOgTNRZbTpAiXwimUFP3dbVUZ8EJu","size":123300,"originalFilename":"Mehrdad Ghoreishi, MD.jpg"}},"articleType":"News","_createdAt":"2025-02-13T18:36:42Z"},{"link":"/view/importance-of-birch-triterpene-findings-for-epidermolysis-bullosa-with-anna-bruckner-md","_rev":"5MymcCPmeJiqJMv8mb3k2O","seoTag":["EB","DEB","JEB","epidermolysis bullosa","dystrophic","junctional","birch bark extract","birch triterpenes","Bruckner"],"is_visible":true,"_createdAt":"2025-02-12T22:12:18Z","summary":"This interview highlights the significance of Bruckner’s recent phase 3 data on birch triterpenes as a potential treatment for dystrophic and junctional EB, as well as patients’ unmet needs.","articleType":"News","_id":"ed88d1f1-14ad-46db-94fb-61dfc6de8043","_updatedAt":"2025-02-14T14:20:15Z","display_summary":true,"url":{"current":"importance-of-birch-triterpene-findings-for-epidermolysis-bullosa-with-anna-bruckner-md","_type":"slug"},"published":"2025-02-13T15:00:00.000Z","authorMapping":[{"_id":"50390873-f609-4f23-b2f5-a613c054c1ac","_updatedAt":"2022-08-24T19:55:19Z","url":{"current":"tim-smith","_type":"slug"},"lastName":"Smith","_rev":"4cB9C6CTf03w1NIxZziTKh","biography":[{"children":[{"_type":"span","marks":[],"text":"Tim Smith joined the MJH Life Sciences team as an assistant editor for HCPLive in August 2022. He graduated from UC Berkeley with a degree in political science, working in multimedia journalism as a staff writer prior to joining MJH. In his spare time, he enjoys reading, watching TV, listening to podcasts, and rock climbing. You can contact him at ","_key":"b4511b246e190"},{"_type":"span","marks":["61fa5a3c02ca"],"text":"tsmith@mjhlifesciences.com","_key":"b4511b246e191"},{"text":".","_key":"b4511b246e192","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"7bbc0f222f10","markDefs":[{"_type":"link","href":"mailto:tsmith@mjhlifesciences.com","_key":"61fa5a3c02ca"}]}],"firstName":"Tim","displayName":"Tim Smith","_createdAt":"2022-08-24T19:55:19Z","_type":"author"},{"_rev":"5MymcCPmeJiqJMv8mb3V4Z","_id":"21637b26-ad24-4ae3-a750-ae55f675fad4","profileImage":{"_type":"mainImage","alt":"Anna Bruckner, MD | Credit: Children's Hospital Colorado","asset":{"_ref":"image-f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523-jpg","_type":"reference"}},"url":{"current":"anna-bruckner-md","_type":"slug"},"lastName":"Bruckner","_createdAt":"2025-02-14T14:19:10Z","_type":"author","biography":[{"_key":"2f3303de3595","markDefs":[],"children":[{"_key":"1f7513203495","_type":"span","marks":[],"text":"Anna Bruckner, MD, is a pediatric dermatologist, a professor of dermatology and pediatrics at the University of Colorado School of Medicine, and section head of pediatric dermatology and co-director of the Epidermolysis Bullosa Center of Excellence at Children’s Hospital Colorado."}],"_type":"block","style":"normal"}],"_updatedAt":"2025-02-14T14:19:10Z","firstName":"Anna","authorType":"expert","displayName":"Anna Bruckner, MD"}],"contentCategory":{"_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384"},"title":"Importance of Birch Triterpene Findings for Epidermolysis Bullosa, with Anna Bruckner, MD","thumbnail":{"asset":{"uploadId":"L3EtOhIpvyiaTiSYB5DK9jU6BLoyeQin","_type":"sanity.imageAsset","sha1hash":"f0a612e87a2c52ae576a9698b131f6e3247cc9d2","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg","_createdAt":"2025-02-12T20:32:59Z","extension":"jpg","metadata":{"_type":"sanity.imageMetadata","palette":{"muted":{"population":3.33,"background":"#9f7563","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0,"background":"#90d4e4"},"darkVibrant":{"background":"#9e1c14","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.77},"lightMuted":{"population":8.37,"background":"#90c2c8","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"foreground":"#fff","title":"#fff","population":8.01,"background":"#bf2217","_type":"sanity.imagePaletteSwatch"},"dominant":{"background":"#90c2c8","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":8.37},"_type":"sanity.imagePalette","darkMuted":{"background":"#633f2f","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":523,"aspectRatio":1,"height":523},"isOpaque":true,"blurHash":"eYI5VxADUHjYnOPUicxuMyi_vMXSwINHS$PUs:Rji_ROV@s.adW=WB"},"_rev":"4m3USuqUEssbssxAO71vst","_id":"image-f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523-jpg","mimeType":"image/jpeg","size":60423,"assetId":"f0a612e87a2c52ae576a9698b131f6e3247cc9d2","originalFilename":"Anna Bruckner MD.jpg","path":"images/0vv8moc6/hcplive/f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg","_updatedAt":"2025-02-12T20:32:59Z"}},"taxonomyMapping":[{"isMainTopic":false,"name":"Dermatology","_id":"topic_dermatology","identifier":"dermatology","perKeywordMapping":["Dermatology","Dermatologic Cancer"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_rev":"uvXJooXtzvjNOyx50DtOz4","_type":"taxonomy","_updatedAt":"2023-03-30T18:37:18Z","summary":[{"_type":"block","style":"normal","_key":"2d374a27e197","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.","_key":"bfe5d86caad9"}]}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"}},{"_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy"},{"name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"_type":"taxonomy","identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0"},{"name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy"}],"body":[{"disableAutoPlayVideo":false,"source":"brightcove","_key":"6de75a13ea15","videoObject":{"videoDescription":"Importance of Birch Triterpene Findings for Epidermolysis Bullosa, with Anna Bruckner, MD","_type":"videoDetails","videoTitle":"Importance of Birch Triterpene Findings for Epidermolysis Bullosa, with Anna Bruckner, MD","thumbnail":{"_type":"image","asset":{"_ref":"image-f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523-jpg","_type":"reference"}},"videoDuration":"PT5M25S"},"_type":"video","videoID":"6368745821112"},{"style":"normal","_key":"94146ff25fe3","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Following the phase 3 EASE study assessing the long-term efficacy and safety profile of birch triterpenes (Filsuvez), also known as Oleogel-S10, for dystrophic EB (DEB) and junctional EB (JEB), the trial’s 24-month, open-label phase took place.","_key":"759b4bc7834f"},{"marks":["sup"],"text":"1","_key":"38c371fa54f8","_type":"span"}],"_type":"block"},{"markDefs":[{"_type":"link","href":"https://www.hcplive.com/view/phase-3-findings-birch-triterpenes-epidermolysis-bullosa-anna-bruckner-md","_key":"228f541777e6","nofollow":true,"blank":true}],"children":[{"marks":[],"text":"In a ","_key":"76c1a0277c75","_type":"span"},{"_key":"51cafe514671","_type":"span","marks":["228f541777e6"],"text":"previous article"},{"_type":"span","marks":[],"text":", ","_key":"4d7bb036a0cf"},{"_type":"span","marks":["em"],"text":"HCPLive","_key":"64b083b6a99f"},{"_type":"span","marks":[],"text":" interviewed EASE investigator Anna Bruckner, MD, a professor of dermatology and pediatric dermatologist at the University of Colorado, to highlight her team’s conclusions on birch triterpenes effectiveness as a treatment for EB. In this segment, Bruckner was asked about the significance of the findings for patients.","_key":"f1822393903a"}],"_type":"block","style":"normal","_key":"6921306ff66c"},{"style":"normal","_key":"339feac53a21","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“I think it is important keep these findings in mind with the overall picture of what exactly patients with EB have have to go through,” Bruckner said. “This therapy is designed to help wounds close faster, but it does not necessarily guarantee that those wounds are going to be staying closed, because it's not replacing any affected abnormal proteins in EB.”","_key":"325515fa99d1"}],"_type":"block"},{"style":"normal","_key":"bd4bd7a9a133","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Nevertheless, Bruckner added that faster wound healing is, for many patients, still clinically meaningful and likely would result in less wound burden. She added that this could even result in a reduction in terms of cost among individuals with EB. Later, Bruckner was asked to comment on patients’ unmet needs.","_key":"8ebc0893e1ce"}],"_type":"block"},{"style":"normal","_key":"edacf09190d1","markDefs":[],"children":[{"text":"“I think that in addition to this therapy, there's 1 other approved treatment for EB,” Bruckner said. “It is beneficial for patients to have faster wound healing. I think what patients would also like to see is more durability of wound healing, meaning that the wounds are not just healing faster but they are staying closed.”","_key":"fff09e3e654a","_type":"span","marks":[]}],"_type":"block"},{"children":[{"text":"Bruckner further noted that only a small number of wounds can be treated at an individual time, highlighting another unmet need among those with EB.","_key":"91be9f573df2","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"d36730ce437a","markDefs":[]},{"_type":"block","style":"normal","_key":"74fc97ec595f","markDefs":[],"children":[{"text":"“So you know treatments that better address the totality [are needed], so that the wound burden of patients are [addressed],” Bruckner said. “Treatments that also address some of the mucosal manifestations, whether or not you know that's the eyes, the mouth, the esophagus, and especially for our patients with recessive dystrophic EB, would also, I think, be really important. We also need better treatments for symptoms.”","_key":"1303371ff2c7","_type":"span","marks":[]}]},{"_type":"block","style":"normal","_key":"8a7b9c4df137","markDefs":[],"children":[{"_key":"1e678ad763c4","_type":"span","marks":[],"text":"Bruckner was then asked about the treatment pipeline for EB and what drugs may become available in the near future."}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"“I think what's exciting is that there are treatments being developed specifically for EB, and we also have the potential to use therapies that have been developed for other indications sort of in an off-label fashion, to treat some of the the symptoms that we're dealing with,” Bruckner said. “But in terms of what might be coming down the pipeline, a company called Abeona that is developing a therapy called pz-cel…looking at genetically corrected keratinocyte graphs for patients with recessive dystrophic EB. So I think that that's certainly very exciting. A similar approach, but using patients fibroblasts that have been genetically corrected, is also being investigated, and that could potentially be promising as well.”","_key":"aea0ed2ff3a4"}],"_type":"block","style":"normal","_key":"14eccdbc8c23"},{"_key":"0f54e57691d3","markDefs":[],"children":[{"_type":"span","marks":[],"text":"To learn more, view the full interview segment posted above.","_key":"cc69e5fc92f9"}],"_type":"block","style":"normal"},{"children":[{"marks":["em"],"text":"The quotes summarized in this article were edited for the purposes of clarity.","_key":"083a10b49332","_type":"span"}],"_type":"block","style":"normal","_key":"470eeb81a613","markDefs":[]},{"_type":"block","style":"normal","_key":"b29c5391057f","markDefs":[],"children":[{"marks":["em"],"text":"Bruckner noted the following disclosures for her interview: Amryt Pharma / Chiesi (contracted research, advisor/consultant, speaker); Castle Creek / Fibrocell (contracted research, advisor/consultant); Krystal Biotech (consultant); Phoenix Tissue Repair (contracted research); Phoenicis Therapeutics (formerly ProQR/Wings) (contracted research); RheaCell (contracted research); Twi Biotechnology (contracted research, consultant).","_key":"c16c39aa3819","_type":"span"}]},{"_type":"block","style":"normal","_key":"c45fe6aa3ef7","markDefs":[],"children":[{"marks":["strong"],"text":"References","_key":"181894864a67","_type":"span"}]},{"level":1,"_type":"block","style":"h6","_key":"2db1e513ffaf","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Murrell DF, Bodemer C, Bruckner AL, Cunningham T, Davis C, Fernández MF, Kiritsi D, Maher L, Sprecher E, Torres Pradilla M, Kern JS. Long-term safety and efficacy of Oleogel-S10 (birch bark extract) in epidermolysis bullosa: 24-month results from the Phase III EASE Study. Br J Dermatol. 2025 Jan 16:ljaf022. doi: 10.1093/bjd/ljaf022. Epub ahead of print. PMID: 39821055.","_key":"e22e8398c8d8"}]}],"_type":"article","ExcludeFromPubMedXML":false},{"_id":"6a67b169-a869-4254-a708-d08de8911d9e","summary":"Bruckner discusses her team’s long-term data on the safety and efficacy of birch bark extract, also known as Oleogel-S10, for those with epidermolysis bullosa.\n","_rev":"5MymcCPmeJiqJMv8mb3sUB","taxonomyMapping":[{"isMainTopic":false,"name":"Dermatology","_id":"topic_dermatology","identifier":"dermatology","perKeywordMapping":["Dermatology","Dermatologic Cancer"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_rev":"uvXJooXtzvjNOyx50DtOz4","_type":"taxonomy","_updatedAt":"2023-03-30T18:37:18Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.","_key":"bfe5d86caad9"}],"_type":"block","style":"normal","_key":"2d374a27e197"}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"}},{"summary":[{"_type":"block","style":"normal","_key":"05eda7184d6f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}]}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z"},{"isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block","style":"normal","_key":"2573f14363ee"}],"_type":"taxonomy","identifier":"clinical"},{"name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy"}],"ExcludeFromPubMedXML":false,"link":"/view/phase-3-findings-birch-triterpenes-epidermolysis-bullosa-anna-bruckner-md","contentCategory":{"_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos"},"_updatedAt":"2025-02-14T14:20:37Z","display_summary":true,"thumbnail":{"asset":{"originalFilename":"Anna Bruckner MD.jpg","path":"images/0vv8moc6/hcplive/f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg","_updatedAt":"2025-02-12T20:32:59Z","uploadId":"L3EtOhIpvyiaTiSYB5DK9jU6BLoyeQin","_type":"sanity.imageAsset","sha1hash":"f0a612e87a2c52ae576a9698b131f6e3247cc9d2","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523.jpg","_createdAt":"2025-02-12T20:32:59Z","extension":"jpg","metadata":{"isOpaque":true,"blurHash":"eYI5VxADUHjYnOPUicxuMyi_vMXSwINHS$PUs:Rji_ROV@s.adW=WB","_type":"sanity.imageMetadata","palette":{"lightMuted":{"background":"#90c2c8","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":8.37},"vibrant":{"foreground":"#fff","title":"#fff","population":8.01,"background":"#bf2217","_type":"sanity.imagePaletteSwatch"},"dominant":{"title":"#fff","population":8.37,"background":"#90c2c8","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"_type":"sanity.imagePalette","darkMuted":{"background":"#633f2f","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3},"muted":{"background":"#9f7563","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.33},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0,"background":"#90d4e4"},"darkVibrant":{"background":"#9e1c14","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.77}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":523,"aspectRatio":1,"height":523}},"_rev":"4m3USuqUEssbssxAO71vst","_id":"image-f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523-jpg","mimeType":"image/jpeg","size":60423,"assetId":"f0a612e87a2c52ae576a9698b131f6e3247cc9d2"}},"articleType":"News","is_visible":true,"_type":"article","title":"Phase 3 Findings on Birch Triterpenes for Epidermolysis Bullosa, with Anna Bruckner, MD","seoTag":["epidermolysis bullosa","EB","DEB","dystrophic","junctional","JEB","birch triterpenes","birch bark extract","EASE"],"authorMapping":[{"displayName":"Tim Smith","_createdAt":"2022-08-24T19:55:19Z","_type":"author","_id":"50390873-f609-4f23-b2f5-a613c054c1ac","_updatedAt":"2022-08-24T19:55:19Z","url":{"current":"tim-smith","_type":"slug"},"lastName":"Smith","_rev":"4cB9C6CTf03w1NIxZziTKh","biography":[{"style":"normal","_key":"7bbc0f222f10","markDefs":[{"_type":"link","href":"mailto:tsmith@mjhlifesciences.com","_key":"61fa5a3c02ca"}],"children":[{"_type":"span","marks":[],"text":"Tim Smith joined the MJH Life Sciences team as an assistant editor for HCPLive in August 2022. He graduated from UC Berkeley with a degree in political science, working in multimedia journalism as a staff writer prior to joining MJH. In his spare time, he enjoys reading, watching TV, listening to podcasts, and rock climbing. You can contact him at ","_key":"b4511b246e190"},{"_type":"span","marks":["61fa5a3c02ca"],"text":"tsmith@mjhlifesciences.com","_key":"b4511b246e191"},{"text":".","_key":"b4511b246e192","_type":"span","marks":[]}],"_type":"block"}],"firstName":"Tim"},{"authorType":"expert","displayName":"Anna Bruckner, MD","_rev":"5MymcCPmeJiqJMv8mb3V4Z","_id":"21637b26-ad24-4ae3-a750-ae55f675fad4","profileImage":{"_type":"mainImage","alt":"Anna Bruckner, MD | Credit: Children's Hospital Colorado","asset":{"_ref":"image-f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523-jpg","_type":"reference"}},"url":{"current":"anna-bruckner-md","_type":"slug"},"lastName":"Bruckner","_createdAt":"2025-02-14T14:19:10Z","_type":"author","biography":[{"_key":"2f3303de3595","markDefs":[],"children":[{"_key":"1f7513203495","_type":"span","marks":[],"text":"Anna Bruckner, MD, is a pediatric dermatologist, a professor of dermatology and pediatrics at the University of Colorado School of Medicine, and section head of pediatric dermatology and co-director of the Epidermolysis Bullosa Center of Excellence at Children’s Hospital Colorado."}],"_type":"block","style":"normal"}],"_updatedAt":"2025-02-14T14:19:10Z","firstName":"Anna"}],"published":"2025-02-12T21:00:39.464Z","body":[{"_key":"47944e9c158e","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/clinical/dermatology","_key":"0372aa87ce2b"}],"children":[{"_key":"7a4121024b1b","_type":"span","marks":[],"text":"The rare and severe dermatologic condition known as "},{"_type":"span","marks":["0372aa87ce2b"],"text":"epidermolysis bullosa (EB)","_key":"921f4ab73186"},{"_type":"span","marks":[],"text":" is a group of severe genetic disorders impacting patients’ skin, promoting fragility and open wounds. Erosions, cutaneous and mucosal blistering, and impaired healing are all manifestations of the disease.","_key":"263b148670b2"}],"_type":"block","style":"normal"},{"style":"normal","_key":"bf64c6758ef6","markDefs":[],"children":[{"_type":"span","marks":[],"text":"A phase 3 study titled EASE was conducted to evaluate the long-term efficacy and safety of birch triterpenes (Filsuvez), also referred to as Oleogel-S10, among individuals with dystrophic EB (DEB) and junctional EB (JEB).","_key":"6a0750a8d360"},{"_type":"span","marks":["sup"],"text":"1","_key":"8a8acaef5fbf"},{"_key":"ca3228a930de","_type":"span","marks":[],"text":" After the EASE trial’s 24-month, open-label phase, the "},{"text":"HCPLive","_key":"ed875649726f","_type":"span","marks":["em"]},{"marks":[],"text":" team spoke with trial investigator Anna Bruckner, MD, professor of dermatology and pediatric dermatologist at the University of Colorado, to discuss new findings.","_key":"4a80c8841838","_type":"span"}],"_type":"block"},{"_type":"video","videoID":"6368719703112","disableAutoPlayVideo":false,"source":"brightcove","_key":"0b0f46715f7e","videoObject":{"videoDescription":"Phase 3 Findings on Birch Triterpenes for Epidermolysis Bullosa, with Anna Bruckner, MD","_type":"videoDetails","videoTitle":"Phase 3 Findings on Birch Triterpenes for Epidermolysis Bullosa, with Anna Bruckner, MD","thumbnail":{"_type":"image","asset":{"_type":"reference","_ref":"image-f0a612e87a2c52ae576a9698b131f6e3247cc9d2-523x523-jpg"}},"videoDuration":"PT3M0S"}},{"_type":"block","style":"normal","_key":"0a346ce8ac17","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“This follows on the heels of a 90-day randomized control trial that looked at patients with epidermolysis bullosa who received [birch triterpenes] to treat the wounds that are associated with EB,” Bruckner explained. “The primary patient population was mainly patients with recessive dystrophic EB, but the study also included patients with dominant dystrophic and junctional EB.”","_key":"a99b30b1d618"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Bruckner highlighted the design of the EASE trial and its open-label extension trial. Those in the treatment cohorts of the double-blind phase entered the single-arm open-label phase, with all EB partial thickness wounds being treated with birch triterpenes. The endpoints of the study included data on adverse events, shifts in body surface area percentage of wounds, wound infection maximum severity, EB Disease Activity and Scarring Index (EBDASI), pruritus, disease severity, pain, and quality of life.","_key":"0f829cce7320"}],"_type":"block","style":"normal","_key":"a8ffed6771fa"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"“The way that this therapy works is that it's a topical product that's applied to all of the open wound areas when the individuals’ bandages are changed,” Bruckner said. “And the major findings that the open-label study showed were that there was a sustained reduction overall in terms of wound burden for these patients and that, overall, the therapy is very safe…”","_key":"6e99e66775e8"}],"_type":"block","style":"normal","_key":"46b635dd74f5"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"EASE’s findings on birch triterpenes were noted by Bruckner as encouraging, given the positive long-term safety profile of the treatment and the sustained reduction the investigators had observed in patients’ wound burden over at least 24 months of therapy.","_key":"623470df5def"}],"_type":"block","style":"normal","_key":"36628c58ce70"},{"children":[{"_type":"span","marks":[],"text":"The study demonstrated that while adverse events (AEs) were noted among 77.1% of subjects, such events were typically mild-to-moderate. Bruckner’s team found severe and serious AEs in 18.0% and 24.4% of participants, respectively.","_key":"f871f5ae2b74"}],"_type":"block","style":"normal","_key":"60da597ac775","markDefs":[]},{"children":[{"text":"“I think it is also important to keep in mind that…these patients do tend to have a lot of medical needs, and the nature of EB means that they're going to have problems with infections or other things that could be going on,” Bruckner said. “But thankfully, this open-label extension did not show that there was an increased risk of problems with treated wounds, such as infections and whatnot. So I think that was very reassuring. Also, there was not an increased risk for other complications that we think about with long-term wounds in patients with EB such as such squamous cell carcinoma.”","_key":"c202c5aa2866","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"a931878b3d7d","markDefs":[]},{"_key":"3e945b61fc06","markDefs":[],"children":[{"marks":[],"text":"For additional information on these new data, view the full interview segment posted above.","_key":"d8cbe446bd84","_type":"span"}],"_type":"block","style":"normal"},{"style":"normal","_key":"359b9f8f205f","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"The quotes contained in this summary were edited for clarity.","_key":"369665c995a3"}],"_type":"block"},{"_type":"block","style":"normal","_key":"b644e58c4b24","markDefs":[],"children":[{"marks":["em"],"text":"Bruckner highlighted the following disclosures for this interview: Amryt Pharma / Chiesi (contracted research, advisor/consultant, speaker); Castle Creek / Fibrocell (contracted research, advisor/consultant); Krystal Biotech (consultant); Phoenix Tissue Repair (contracted research); Phoenicis Therapeutics (formerly ProQR/Wings) (contracted research); RheaCell (contracted research); Twi Biotechnology (contracted research, consultant).","_key":"3b68198d5a0b","_type":"span"}]},{"style":"normal","_key":"ec24a0a2f946","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"References","_key":"0d17c50ac065"}],"_type":"block"},{"level":1,"_type":"block","style":"h6","_key":"3f3907159f6b","listItem":"number","markDefs":[],"children":[{"text":"Murrell DF, Bodemer C, Bruckner AL, Cunningham T, Davis C, Fernández MF, Kiritsi D, Maher L, Sprecher E, Torres Pradilla M, Kern JS. Long-term safety and efficacy of Oleogel-S10 (birch bark extract) in epidermolysis bullosa: 24-month results from the Phase III EASE Study. Br J Dermatol. 2025 Jan 16:ljaf022. doi: 10.1093/bjd/ljaf022. Epub ahead of print. PMID: 39821055.","_key":"b2ee0064a2da","_type":"span","marks":[]}]}],"url":{"current":"phase-3-findings-birch-triterpenes-epidermolysis-bullosa-anna-bruckner-md","_type":"slug"},"_createdAt":"2025-02-12T20:30:17Z"},{"thumbnail":{"asset":{"size":18576,"assetId":"3d226c297e859ec68a7f76c69fdccc0fda1962a0","_createdAt":"2023-05-17T03:40:24Z","originalFilename":"Hebert-Adelaide.jpeg","_type":"sanity.imageAsset","path":"images/0vv8moc6/hcplive/3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg","_id":"image-3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300-jpg","metadata":{"palette":{"vibrant":{"foreground":"#fff","title":"#fff","population":9.12,"background":"#6b8be4","_type":"sanity.imagePaletteSwatch"},"dominant":{"foreground":"#fff","title":"#fff","population":13.68,"background":"#361f1b","_type":"sanity.imagePaletteSwatch"},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":13.68,"background":"#361f1b"},"muted":{"foreground":"#fff","title":"#fff","population":0.07,"background":"#5059a4","_type":"sanity.imagePaletteSwatch"},"lightVibrant":{"population":0.1,"background":"#7192f4","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"darkVibrant":{"foreground":"#fff","title":"#fff","population":2.4,"background":"#1c3466","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.12,"background":"#ccafa1"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":300,"aspectRatio":1,"height":300},"isOpaque":true,"blurHash":"ebH2BLNh1U-o-qI_s*xtNGRhERay$yoLRhWuofs,R%V@ogaxW9flR*","_type":"sanity.imageMetadata"},"uploadId":"kK6U1OTfRtyAFy7fYd3BDJmrDrlSHvrm","mimeType":"image/jpeg","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg","_updatedAt":"2023-05-17T03:40:24Z","extension":"jpg","_rev":"7OiXQvfCjcWTiVgzfKxCAI","sha1hash":"3d226c297e859ec68a7f76c69fdccc0fda1962a0"}},"seoTag":["AD","atopic dermatitis","eczema","tapinarof cream","1%","Vtama","2 years"],"published":"2025-02-06T15:00:00.000Z","url":{"current":"safety-profile-accessibility-tapinarof-cream-atopic-dermatitis-adelaide-hebert-md","_type":"slug"},"link":"/view/safety-profile-accessibility-tapinarof-cream-atopic-dermatitis-adelaide-hebert-md","contentCategory":{"_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos"},"_createdAt":"2025-02-05T22:15:00Z","summary":"This segment of Hebert’s interview features a discussion regarding the safety profile of tapinarof 1% for patients aged 2 years and older with atopic dermatitis.","_type":"article","display_summary":true,"_updatedAt":"2025-02-05T22:32:25Z","body":[{"_key":"4f82242bc3da","videoObject":{"videoDescription":"Safety Profile, Accessibility of Tapinarof Cream for Atopic Dermatitis, with Adelaide Hebert, MD","_type":"videoDetails","videoTitle":"Safety Profile, Accessibility of Tapinarof Cream for Atopic Dermatitis, with Adelaide Hebert, MD","thumbnail":{"_type":"image","asset":{"_ref":"image-3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300-jpg","_type":"reference"}},"videoDuration":"PT4M05S"},"_type":"video","videoID":"6368327505112","disableAutoPlayVideo":false,"source":"brightcove"},{"children":[{"_type":"span","marks":[],"text":"The ","_key":"0d71c7b5652c"},{"_type":"span","marks":["5cd75fcca7ed"],"text":"December 2024 US Food and Drug Administration (FDA) approval","_key":"8d55de780e16"},{"_type":"span","marks":[],"text":" announced by Organon for tapinarof (Vtama) cream 1% expanded the drug’s indicated age range, with patients diagnosed with atopic dermatitis aged 2 years and older now approved to receive the medication.","_key":"740bfa482885"},{"_type":"span","marks":["sup"],"text":"1,2","_key":"76b39a971cae"}],"_type":"block","style":"normal","_key":"5a1d4f7b9eb3","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/view/fda-approves-tapinarof-cream-adult-pediatric-patients-atopic-dermatitis","_key":"5cd75fcca7ed","nofollow":true}]},{"markDefs":[{"href":"https://www.hcplive.com/view/impact-of-tapinarof-cream-approval-for-atopic-dermatitis-adelaide-hebert-md","_key":"c875c693142a","nofollow":true,"blank":true,"_type":"link"}],"children":[{"_type":"span","marks":[],"text":"In a ","_key":"71ca5c166419"},{"_type":"span","marks":["c875c693142a"],"text":"previous interview","_key":"4fabfcc7465e"},{"marks":[],"text":", the FDA approval of this aryl hydrocarbon receptor agonist and the ADORING phase 3 clinical trial program leading to the approval were discussed between the ","_key":"26084a7705c0","_type":"span"},{"marks":["em"],"text":"HCPLive","_key":"4e1c4c2c9a40","_type":"span"},{"marks":[],"text":" editorial team and ADORING investigator Adelaide A. Hebert, MD, a professor of dermatology and pediatrics at UTHealth Houston. In the above segment of her interview, Hebert was asked about the drug’s safety profile in her team’s findings.","_key":"2533ce47b53c","_type":"span"}],"_type":"block","style":"normal","_key":"4fa8538fc570"},{"style":"normal","_key":"4c2dc4d9be18","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“We had excellent results with long term safety,” Hebert explained. “We did not see new emergent adverse events in the long term safety study that would have suggested application over that duration, up to a full 52 weeks in a full year of treatment…[would] lead to any undue sequelae. It didn't raise any concerns and we didn't see anything we call a signal, which is something we would want to identify, and it remains one of the purposes of these long term safety evaluations.”","_key":"884825b95a6c"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Overall, Hebert highlighted that in the ADORING trial, tapinarof cream 1% was well-tolerated among study subjects.","_key":"edc4d5020343"}],"_type":"block","style":"normal","_key":"7bc37c82b3ec"},{"_key":"23359c6c7a1e","markDefs":[],"children":[{"marks":[],"text":"“One thing we learned in addition was many of the patients can develop time off medication because of the remitive effect of this drug,” Hebert said. “And the duration of that time off drug with disease control was as much as 80 days. That is really a remarkable interval of treatment-free time when you have a condition that's chronic, relapsing, and prone to flares. So this, again, was a very important learning arena for us, as we did this clinical trial out to the 52 week time point.”","_key":"806750e18f52","_type":"span"}],"_type":"block","style":"normal"},{"_key":"cc7281c80612","markDefs":[],"children":[{"marks":[],"text":"Hebert highlighted that the ADORING investigators were pleased that the patients could go without medication during this brief period. Then, she was asked about any potential barriers to accessibility to this medication for patients aged 2 years and older with atopic dermatitis.","_key":"47018db79fb4","_type":"span"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"7786dc21b740","markDefs":[],"children":[{"marks":[],"text":"“I think 1 of the things for those of us, particularly in the pediatric realm, is to begin to generate awareness in our colleagues within pediatrics and family practice,” Hebert said. “Because they may or may not have heard of this drug, as it was only approved previously for those patients 18 above with psoriasis, so they will have had little opportunity to see patients who are on the drug, or to have prescribed it potentially themselves. We need to educate these colleagues, because it is once-a-day, it is steroid-free, and it can be used as a single drug over all body parts. I don't think many of our pediatric colleagues are aware of what we call this remitive effect.”","_key":"fa60976a21c3","_type":"span"}]},{"markDefs":[],"children":[{"marks":[],"text":"To find out more information about tapinarof 1% and its safety profile among patients aged 2 years and older with atopic dermatitis, view the full video posted above.","_key":"a21dd5f02e1f","_type":"span"}],"_type":"block","style":"normal","_key":"ca2bc2d95a8a"},{"_type":"block","style":"normal","_key":"dc02c87e45bd","markDefs":[],"children":[{"_key":"1d57ded3c310","_type":"span","marks":["em"],"text":"The quotes used in this summary were edited for the purposes of clarity."}]},{"markDefs":[],"children":[{"_key":"8869ffbec345","_type":"span","marks":["em"],"text":"Hebert's disclosures are as follows: Research grants paid to the medical school (Dermavant, Arcutis, Pfizer, Leo Pharma, Incyte), Honoraria (Dermavant, Arcutis, Pfizer, Leo Pharma, Incyte, Sun Pharma, Ortho Dermatology, Apogee), DSMB (Sanofi Regeneron, OrthoDermatologics, GSK, Apogee)."}],"_type":"block","style":"normal","_key":"98484d9d6133"},{"children":[{"marks":["strong"],"text":"References","_key":"f72fb5e4e7f4","_type":"span"}],"_type":"block","style":"normal","_key":"dad4e09114e8","markDefs":[]},{"_key":"a568a39a587d","listItem":"number","markDefs":[],"children":[{"text":"FDA Approves VTAMA® (tapinarof) cream, 1% for the Treatment of Atopic Dermatitis in Adults and Children 2 Years of Age and Older. Organon. December 16, 2024. https://www.organon.com/news/fda-approves-vtama-tapinarof-cream-1-for-the-treatment-of-atopic-dermatitis-in-adults-and-children-2-years-of-age-and-older/. Date accessed: December 16, 2024.","_key":"49d2eac07e9c","_type":"span","marks":["sup"]}],"level":1,"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":["sup"],"text":"Update on FDA Review of VTAMA® (tapinarof) Cream, 1% for the Treatment of Atopic Dermatitis in Adults and Children 2 Years of Age and Older. Organon. November 5, 2024. https://www.organon.com/news/update-on-fda-review-of-vtama-tapinarof-cream-1-for-the-treatment-of-atopic-dermatitis-in-adults-and-children-2-years-of-age-and-older/. Date accessed: December 16, 2024.","_key":"f091e0924c0e"}],"level":1,"_type":"block","style":"normal","_key":"467efdb06ea4","listItem":"number","markDefs":[]}],"authorMapping":[{"firstName":"Tim","displayName":"Tim Smith","_createdAt":"2022-08-24T19:55:19Z","_type":"author","_id":"50390873-f609-4f23-b2f5-a613c054c1ac","_updatedAt":"2022-08-24T19:55:19Z","url":{"current":"tim-smith","_type":"slug"},"lastName":"Smith","_rev":"4cB9C6CTf03w1NIxZziTKh","biography":[{"_type":"block","style":"normal","_key":"7bbc0f222f10","markDefs":[{"_type":"link","href":"mailto:tsmith@mjhlifesciences.com","_key":"61fa5a3c02ca"}],"children":[{"_type":"span","marks":[],"text":"Tim Smith joined the MJH Life Sciences team as an assistant editor for HCPLive in August 2022. He graduated from UC Berkeley with a degree in political science, working in multimedia journalism as a staff writer prior to joining MJH. In his spare time, he enjoys reading, watching TV, listening to podcasts, and rock climbing. You can contact him at ","_key":"b4511b246e190"},{"_type":"span","marks":["61fa5a3c02ca"],"text":"tsmith@mjhlifesciences.com","_key":"b4511b246e191"},{"text":".","_key":"b4511b246e192","_type":"span","marks":[]}]}]},{"lastName":"Hebert","displayName":"Adelaide A. Hebert, MD","_createdAt":"2023-01-25T20:17:14Z","_type":"author","middleName":"A.","_id":"4a052d46-c30c-4800-bd0e-6c3ed55206e2","url":{"current":"adelaide-a-hebert-md","_type":"slug"},"firstName":"Adelaide","_rev":"2MCZWtMCW1jfJl4yA0fjPZ","_updatedAt":"2023-01-25T20:17:14Z"}],"_rev":"BrRurCA6RvzuZ0A2V38Zgp","is_visible":true,"ExcludeFromPubMedXML":false,"_id":"42125cf9-6401-4110-aee0-f637a3f6f2f0","taxonomyMapping":[{"name":"Atopic Dermatitis","_updatedAt":"2024-10-23T13:10:35Z","summary":[{"markDefs":[],"children":[{"_key":"9faef397dc21","_type":"span","marks":[],"text":"On the "},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"95494ef9d956"},{"_key":"a55149ee5114","_type":"span","marks":[],"text":"Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development."}],"_type":"block","style":"normal","_key":"f61ee45b707b"}],"pixelTrackingCode":{"_ref":"e4b5b2a6-8742-42cb-bf97-fa1a8bfd2d53","_type":"reference"},"_type":"taxonomy","_id":"topic_atopic-dermatitis","identifier":"atopic-dermatitis","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"2sK05ae9cc6f2xw80LsqdL"},{"_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News"},{"_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}]}],"_type":"taxonomy","identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z"}],"articleType":"News","title":"Safety Profile, Accessibility of Tapinarof Cream 1% for Atopic Dermatitis, with Adelaide Hebert, MD"},{"articleType":"News","_id":"d65054a3-4990-4317-8549-c6c22631cb94","_updatedAt":"2025-02-05T22:32:47Z","published":"2025-02-05T19:30:56.518Z","taxonomyMapping":[{"summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f"}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z"},{"isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"_type":"block","style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}]}],"_type":"taxonomy","identifier":"clinical"},{"summary":[{"_type":"block","style":"normal","_key":"f61ee45b707b","markDefs":[],"children":[{"_key":"9faef397dc21","_type":"span","marks":[],"text":"On the "},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"95494ef9d956"},{"_key":"a55149ee5114","_type":"span","marks":[],"text":"Atopic Dermatitis condition center page, audiences can find a variety of coverage mediums for medical news and updates, including articles, video interviews, podcasts, and breaking news on dermatitis research, treatment, and drug development."}]}],"pixelTrackingCode":{"_ref":"e4b5b2a6-8742-42cb-bf97-fa1a8bfd2d53","_type":"reference"},"_type":"taxonomy","_id":"topic_atopic-dermatitis","identifier":"atopic-dermatitis","parent":{"_ref":"topic_dermatology","_type":"reference"},"_createdAt":"2020-05-20T18:09:49Z","_rev":"2sK05ae9cc6f2xw80LsqdL","name":"Atopic Dermatitis","_updatedAt":"2024-10-23T13:10:35Z"},{"_type":"taxonomy","_updatedAt":"2023-03-30T18:37:18Z","summary":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The HCPLive dermatology page is a resource for medical news and expert insights on skin disease. This page features expert-led coverage, articles, videos and research on the therapies and development of treatments for dermatologic conditions, and more.","_key":"bfe5d86caad9"}],"_type":"block","style":"normal","_key":"2d374a27e197"}],"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"isMainTopic":false,"name":"Dermatology","_id":"topic_dermatology","identifier":"dermatology","perKeywordMapping":["Dermatology","Dermatologic Cancer"],"cmeType":"per","_createdAt":"2020-05-20T18:09:49Z","_rev":"uvXJooXtzvjNOyx50DtOz4"},{"name":"Videos","_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy"}],"title":"Impact of Tapinarof Cream Approval for Atopic Dermatitis, with Adelaide Hebert, MD","authorMapping":[{"_updatedAt":"2023-01-25T20:17:14Z","lastName":"Hebert","displayName":"Adelaide A. Hebert, MD","_createdAt":"2023-01-25T20:17:14Z","_type":"author","middleName":"A.","_id":"4a052d46-c30c-4800-bd0e-6c3ed55206e2","url":{"current":"adelaide-a-hebert-md","_type":"slug"},"firstName":"Adelaide","_rev":"2MCZWtMCW1jfJl4yA0fjPZ"},{"lastName":"Smith","_rev":"4cB9C6CTf03w1NIxZziTKh","biography":[{"_type":"block","style":"normal","_key":"7bbc0f222f10","markDefs":[{"_type":"link","href":"mailto:tsmith@mjhlifesciences.com","_key":"61fa5a3c02ca"}],"children":[{"_type":"span","marks":[],"text":"Tim Smith joined the MJH Life Sciences team as an assistant editor for HCPLive in August 2022. He graduated from UC Berkeley with a degree in political science, working in multimedia journalism as a staff writer prior to joining MJH. In his spare time, he enjoys reading, watching TV, listening to podcasts, and rock climbing. You can contact him at ","_key":"b4511b246e190"},{"_type":"span","marks":["61fa5a3c02ca"],"text":"tsmith@mjhlifesciences.com","_key":"b4511b246e191"},{"text":".","_key":"b4511b246e192","_type":"span","marks":[]}]}],"firstName":"Tim","displayName":"Tim Smith","_createdAt":"2022-08-24T19:55:19Z","_type":"author","_id":"50390873-f609-4f23-b2f5-a613c054c1ac","_updatedAt":"2022-08-24T19:55:19Z","url":{"current":"tim-smith","_type":"slug"}}],"body":[{"videoID":"6368320108112","disableAutoPlayVideo":false,"source":"brightcove","_key":"aa69e444de55","videoObject":{"thumbnail":{"asset":{"_ref":"image-3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300-jpg","_type":"reference"},"_type":"image"},"videoDuration":"PT3M23S","videoDescription":"Impact of Tapinarof Cream Approval for Atopic Dermatitis, Adelaide Hebert, MD","_type":"videoDetails","videoTitle":"Impact of Tapinarof Cream Approval for Atopic Dermatitis, Adelaide Hebert, MD"},"_type":"video"},{"children":[{"marks":[],"text":"Few disease states have seen the same level of advancement in recent years as ","_key":"f244ec0012e0","_type":"span"},{"marks":["6e299e1a4a11"],"text":"atopic dermatitis","_key":"4c9f96b45aa2","_type":"span"},{"_type":"span","marks":[],"text":", with notable breakthroughs, such as the December 16, 2024, ","_key":"2c055937ec58"},{"_type":"span","marks":["8caa32a7dc90"],"text":"US Food and Drug Administration (FDA)","_key":"9750a0ef90bb"},{"_key":"4589d8237ca7","_type":"span","marks":[],"text":" approval of tapinarof cream 1% (Vtama)."},{"_type":"span","marks":["sup"],"text":"1","_key":"25f1b692d67f"}],"_type":"block","style":"normal","_key":"cc13d752bc42","markDefs":[{"_type":"link","href":"https://www.hcplive.com/clinical/atopic-dermatitis","_key":"6e299e1a4a11"},{"_type":"link","href":"https://www.hcplive.com/clinical/fda-news","_key":"8caa32a7dc90"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Tapinarof is an aryl hydrocarbon receptor agonist and its approval expands the range of available treatments for atopic dermatitis, 1 of the most prevalent dermatological disorders, providing a new option for patients managing this widespread condition. To discuss the approval’s significance, the ","_key":"550c8b6c802c"},{"_type":"span","marks":["em"],"text":"HCPLive","_key":"590e1f90b6ca"},{"_type":"span","marks":[],"text":" editorial team spoke with Adelaide A. Hebert, MD, a professor of dermatology and pediatrics at UTHealth Houston.","_key":"fdddd67b6061"}],"_type":"block","style":"normal","_key":"988c0c76dd18"},{"style":"normal","_key":"1413d420a706","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“One of the things I think is tremendously exciting is that tapinarof offers us a single dose strength to use either for atopic dermatitis or psoriasis across age groups,” Hebert said. “It's a 1-day application, and the drug is also steroid free, which is very appealing in this era of, unfortunately, steroid-phobia. We needed additional medications to help patients who suffer with a chronic relapsing disease, such as atopic dermatitis, but also psoriasis.”","_key":"d478f778c963"}],"_type":"block"},{"_key":"155774fec92a","markDefs":[],"children":[{"text":"The drug boasts prior approvals dating back to 2022 when the agent received approval for the treatment of plaque psoriasis in adults, and the latest approval for tapinarof cream indicates the agent for treatment of atopic dermatitis in patients aged 2 years and older. The FDA approval for Organon’s aryl hydrocarbon receptor agonist, which occurred more than 2 months prior to its scheduled March 12, 2025 PDUFA, was based on significant efficacy in the ADORING clinical trial program, including ADORING 3, a 48-week extension study.","_key":"368ba9ede563","_type":"span","marks":[]},{"marks":["sup"],"text":"2","_key":"f6bbd98d35e6","_type":"span"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"In ADORING 1 and 2, tapinarof cream 1% demonstrated robust efficacy for atopic dermatitis. In ADORING 1, 45.4% of patients treated with tapinarof achieved clear (0) or almost clear (1) skin with at least a 2-grade improvement on the Validated Investigator Global Assessment for AD (vIGA-AD) scale, compared to 13.9% in the placebo group. Similarly, in ADORING 2, 46.4% of tapinarof-treated patients met these criteria versus 18.0% with placebo (","_key":"4944232357c0"},{"_type":"span","marks":["em"],"text":"P","_key":"12aaed5cf0bd"},{"marks":[],"text":" \u003c 0.0001 in both trials). According to a release from Organon, tapinarof cream also improved EASI 75 scores and reduced itch severity in participants aged 12 and older.","_key":"3082de1e465f","_type":"span"},{"_type":"span","marks":["sup"],"text":"1","_key":"cf370c737ace"}],"_type":"block","style":"normal","_key":"72b74672b675"},{"markDefs":[],"children":[{"_key":"0ef5cbe2cfdd","_type":"span","marks":[],"text":"With an interest in learning more about the approval and how it impacts the landscape of disease management for the dermatological condition, our editorial team asked Herbert about some of the treatment's potential advantages."}],"_type":"block","style":"normal","_key":"e6aa489293c5"},{"children":[{"_type":"span","marks":[],"text":"“One of the big advantages we have with tapinarof 1% is that the percentage that has been approved for about 2 years now for psoriasis in those patients aged 18 and above is exactly the same cream, both in formulation, tube size, everything,\" Hebert said. \"We didn't have to really reinvent this. This drug is already on the shelf. We just now have a greater expansion of its indication in both the pediatric realm and into the realm of atop a dermatitis.”","_key":"449746cbadc8"}],"_type":"block","style":"normal","_key":"8494d40db2da","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"For additional information, view the full interview posted above. ","_key":"2ff779049964"}],"_type":"block","style":"normal","_key":"8504b2cabe90","markDefs":[]},{"_key":"947730c080eb","markDefs":[],"children":[{"_key":"d8d4c5afbdc2","_type":"span","marks":["em"],"text":"The quotes contained in this interview summary were edited for clarity."}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Hebert's disclosures are as follows: Research grants paid to the medical school (Dermavant, Arcutis, Pfizer, Leo Pharma, Incyte), Honoraria (Dermavant, Arcutis, Pfizer, Leo Pharma, Incyte, Sun Pharma, Ortho Dermatology, Apogee), DSMB (Sanofi Regeneron, OrthoDermatologics, GSK, Apogee).","_key":"3e750bf2ef2e"}],"_type":"block","style":"normal","_key":"b6bba152a102"},{"_type":"block","style":"normal","_key":"e8de370d5ff8","markDefs":[],"children":[{"marks":["strong"],"text":"References","_key":"6de3a8c121f6","_type":"span"}]},{"children":[{"_type":"span","marks":["sup"],"text":"FDA Approves VTAMA® (tapinarof) cream, 1% for the Treatment of Atopic Dermatitis in Adults and Children 2 Years of Age and Older. Organon. December 16, 2024. https://www.organon.com/news/fda-approves-vtama-tapinarof-cream-1-for-the-treatment-of-atopic-dermatitis-in-adults-and-children-2-years-of-age-and-older/. Date accessed: December 16, 2024.","_key":"63ab8694c3be"}],"level":1,"_type":"block","style":"normal","_key":"1d92daf533df","listItem":"number","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["sup"],"text":"Update on FDA Review of VTAMA® (tapinarof) Cream, 1% for the Treatment of Atopic Dermatitis in Adults and Children 2 Years of Age and Older. Organon. November 5, 2024. https://www.organon.com/news/update-on-fda-review-of-vtama-tapinarof-cream-1-for-the-treatment-of-atopic-dermatitis-in-adults-and-children-2-years-of-age-and-older/. Date accessed: December 16, 2024.","_key":"b6946f0ff92a"}],"level":1,"_type":"block","style":"normal","_key":"61e6fac62afc","listItem":"number"}],"_type":"article","link":"/view/impact-of-tapinarof-cream-approval-for-atopic-dermatitis-adelaide-hebert-md","_rev":"BrRurCA6RvzuZ0A2V38aHv","ExcludeFromPubMedXML":false,"summary":"Adelaide Hebert, MD, discusses the impact of the recent approval for tapinarof cream in the management of atopic dermatitis. ","contentCategory":{"_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z","_createdAt":"2020-05-26T14:29:02Z"},"display_summary":true,"thumbnail":{"asset":{"assetId":"3d226c297e859ec68a7f76c69fdccc0fda1962a0","_createdAt":"2023-05-17T03:40:24Z","originalFilename":"Hebert-Adelaide.jpeg","_type":"sanity.imageAsset","path":"images/0vv8moc6/hcplive/3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg","_id":"image-3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300-jpg","metadata":{"_type":"sanity.imageMetadata","palette":{"lightMuted":{"population":0.12,"background":"#ccafa1","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"title":"#fff","population":9.12,"background":"#6b8be4","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"foreground":"#fff","title":"#fff","population":13.68,"background":"#361f1b","_type":"sanity.imagePaletteSwatch"},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":13.68,"background":"#361f1b"},"muted":{"background":"#5059a4","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.07},"lightVibrant":{"population":0.1,"background":"#7192f4","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"darkVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.4,"background":"#1c3466"}},"hasAlpha":false,"lqip":"data:image/jpeg;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":300,"aspectRatio":1,"height":300},"isOpaque":true,"blurHash":"ebH2BLNh1U-o-qI_s*xtNGRhERay$yoLRhWuofs,R%V@ogaxW9flR*"},"uploadId":"kK6U1OTfRtyAFy7fYd3BDJmrDrlSHvrm","mimeType":"image/jpeg","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/3d226c297e859ec68a7f76c69fdccc0fda1962a0-300x300.jpg","_updatedAt":"2023-05-17T03:40:24Z","extension":"jpg","_rev":"7OiXQvfCjcWTiVgzfKxCAI","sha1hash":"3d226c297e859ec68a7f76c69fdccc0fda1962a0","size":18576}},"url":{"current":"impact-of-tapinarof-cream-approval-for-atopic-dermatitis-adelaide-hebert-md","_type":"slug"},"is_visible":true,"_createdAt":"2025-02-05T18:17:04Z"},{"_id":"870aa091-39b9-4aa8-9648-0c9e907205fd","ExcludeFromPubMedXML":false,"taxonomyMapping":[{"summary":[{"children":[{"_type":"span","marks":[],"text":"On the ","_key":"2de35df2ca65"},{"_type":"span","marks":["em"],"text":"HCPLive ","_key":"6912a6d04ee0"},{"_type":"span","marks":[],"text":"news page, resources on the topics of disease- and specialty-specific medical news and expert insight can be found. Content includes articles, interviews, videos, podcasts, and breaking news on health care research, treatment, and drug development.","_key":"618b8c055ef1"}],"_type":"block","style":"normal","_key":"05eda7184d6f","markDefs":[]}],"identifier":"news","_rev":"u7gdIn0FVGomM0agA7SXsN","_type":"taxonomy","_createdAt":"2020-05-21T18:00:24Z","name":"News","_id":"00c35849-3d97-4901-be93-6e229c2a844d","_updatedAt":"2024-09-27T20:47:32Z"},{"identifier":"clinical","isMainTopic":true,"_createdAt":"2020-05-20T18:05:03Z","_rev":"jFlyVyB0S45zgvAzVefOS0","name":"Clinical","_id":"703a1bdf-1645-43ac-9e1b-55e382091532","_updatedAt":"2021-11-10T19:26:47Z","summary":[{"style":"normal","_key":"2573f14363ee","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The ","_key":"eee871ba2638"},{"text":"HCPLive ","_key":"17c44b92092c","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":"clinical page is a resource for content on every specialty, disease, and topic available on our medical news site.","_key":"533147ea7c57"}],"_type":"block"}],"_type":"taxonomy"},{"parent":{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},"_rev":"cOrVoLHD1qT5y0raOasIM3","name":"Hepatology","usedForRecommendations":false,"_updatedAt":"2023-04-25T23:31:20Z","isMainTopic":true,"_createdAt":"2023-04-25T23:31:12Z","_type":"taxonomy","_id":"44abda14-7b81-4a4f-ac34-a5e848aa62b2","identifier":"hepatology"},{"summary":[{"children":[{"_type":"span","marks":[],"text":"The HCPLive MASH \u0026 MASLD page is a comprehensive resource for clinical news and insights on metabolic dysfunction-associated steatotic liver disease and steatohepatitis. This page consists of interviews, articles, podcasts, and videos on the research, treatment and development of therapies for fatty liver disease, steatohepatitis, and more.","_key":"a026eabb7fb50"}],"_type":"block","style":"normal","_key":"a9aa56b4170f","markDefs":[]}],"_createdAt":"2024-02-15T17:57:46Z","_type":"taxonomy","name":"MASH / MASLD","usedForRecommendations":false,"_id":"82d0e148-23b4-480a-b0a5-f5bddfaaa00f","identifier":"mash-masld","parent":{"_type":"reference","_ref":"44abda14-7b81-4a4f-ac34-a5e848aa62b2"},"_rev":"u7KWSLocEROtTPtelfBFOe","video":{"isTaxVideo":false},"_updatedAt":"2024-02-15T17:57:46Z"},{"_id":"84524156-7b84-4e11-841f-e7a6e0f43d74","_updatedAt":"2021-10-20T12:01:08Z","identifier":"videos","_createdAt":"2020-07-08T15:02:08Z","_rev":"pUee4LE8OL50hthUx9KRKn","_type":"taxonomy","name":"Videos"}],"_type":"article","published":"2025-02-05T11:00:00.000Z","link":"/view/metabolic-surgery-benefit-mash-related-cirrhosis-soba-laique-md","articleType":"News","authorMapping":[{"lastName":"Brooks","_createdAt":"2023-08-16T21:01:55Z","_rev":"sXRLufgca24g5WFAwOy51f","_id":"a4f8c360-5ae6-48cb-99c0-286a6b76f037","biography":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Abigail Brooks is an assistant editor for ","_key":"1d7645ea6da80"},{"_type":"span","marks":["em"],"text":"HCPLive. ","_key":"1d7645ea6da81"},{"_type":"span","marks":[],"text":"She joined MJH Life Sciences in August 2023 shortly after graduating from Monmouth University where she earned her BA in Communication with a concentration in Public Relations/Journalism and later an MA in Interactive Digital Media. She enjoys traveling, running, and reading books. She can be reached at abrooks@mjhlifesciences.com.","_key":"1d7645ea6da82"}],"_type":"block","style":"normal","_key":"ad4ff818a6d3"}],"_updatedAt":"2023-08-16T21:01:55Z","firstName":"Abigail","displayName":"Abigail Brooks, MA","_type":"author","profileImage":{"_type":"mainImage","asset":{"_ref":"image-93bd0088a30dd94cde45491e60398457d8055321-1928x2700-jpg","_type":"reference"}},"url":{"current":"abigail-brooks","_type":"slug"}},{"biography":[{"children":[{"_type":"span","marks":[],"text":"Sobia Laique, MD, is a gastroenterologist and transplant hepatologist at Cleveland Clinic.","_key":"2006c5048235"}],"_type":"block","style":"normal","_key":"c183f08c4bcf","markDefs":[]}],"profileImage":{"_type":"mainImage","alt":"Sobia Laique, MD | Credit: Cleveland Clinic","asset":{"_ref":"image-2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954-png","_type":"reference"}},"lastName":"Laique","_createdAt":"2025-02-03T21:37:38Z","_updatedAt":"2025-02-03T21:38:39Z","url":{"_type":"slug","current":"sobia-laique-md"},"firstName":"Sobia","authorType":"expert","displayName":"Sobia Laique, MD","_rev":"NM6jX99S8M6pthZactzdDU","_type":"author","_id":"aafaf61f-ee4e-4399-b14e-092c8c1be7e0"}],"body":[{"disableAutoPlayVideo":true,"source":"brightcove","_key":"56e698e615b8","videoObject":{"_type":"videoDetails","videoTitle":"Metabolic Surgery’s Benefit for MASH-Related Cirrhosis, with Soba Laique, MD","thumbnail":{"asset":{"_ref":"image-51d1bc5479644e2a6b877c8f57e33568542ad32d-1012x568-png","_type":"reference"},"_type":"image"},"videoDuration":"PT7M58S","videoDescription":"Metabolic Surgery’s Benefit for MASH-Related Cirrhosis, with Soba Laique, MD"},"_type":"video","videoID":"6368249181112"},{"_key":"5f156d945675","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/clinical/mash-masld","_key":"dfe93e2e87bc","nofollow":true}],"children":[{"_type":"span","marks":[],"text":"Resmetirom (Rezdiffra) made history in 2024 when it became the first therapeutic to earn US Food and Drug Administration approval for the treatment of ","_key":"161be30578d7"},{"_key":"ebb329f9a349","_type":"span","marks":["dfe93e2e87bc"],"text":"metabolic dysfunction-associated steatohepatitis (MASH)"},{"_type":"span","marks":[],"text":".","_key":"ad2b2b63c137"},{"_key":"591318ec0acb","_type":"span","marks":["sup"],"text":"1"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Although the approval represented a major breakthrough for the field of hepatology and offered a long-awaited pharmacologic treatment option for many affected patients, it did not address the unmet needs of all MASH patients. Indicated specifically for those with noncirrhotic MASH and moderate to advanced fibrosis, resmetirom’s approval did not include patients with MASH-related cirrhosis, a population that still does not have an FDA-approved treatment.","_key":"199aece77b7a"},{"_type":"span","marks":["sup"],"text":"1","_key":"d44a780f1cb5"}],"_type":"block","style":"normal","_key":"51745481192b"},{"markDefs":[],"children":[{"text":"In the absence of medical therapies, recent research has focused on other interventions to help improve outcomes for these patients. Designed to examine the long-term association between metabolic surgery and the risk of progression to major adverse liver outcomes (MALO), the Surgical Procedures Eliminate Compensated Cirrhosis In Advancing Long-term (SPECCIAL) study enrolled patients with compensated biopsy-proven MASH-related cirrhosis and compared outcomes between metabolic surgery and medical management.","_key":"f31dfcbd6a03","_type":"span","marks":[]},{"_key":"2e98596acd03","_type":"span","marks":["sup"],"text":"2"}],"_type":"block","style":"normal","_key":"e50b175993ce"},{"style":"normal","_key":"92c81e9c9e49","markDefs":[],"children":[{"_key":"0b06b04496e1","_type":"span","marks":[],"text":"“What our findings revealed was a 72% lower risk of incident MALOs and an 80% lower risk of hepatic decompensation in the surgical group, which are staggering numbers to see,” Sobia Laique, MD, a gastroenterologist and transplant hepatologist at Cleveland Clinic, explained in an interview with "},{"marks":["em"],"text":"HCPLive","_key":"1eec0def7cb2","_type":"span"},{"_type":"span","marks":[],"text":".","_key":"4ff8de517d54"}],"_type":"block"},{"_type":"block","style":"normal","_key":"bb0908b074d4","markDefs":[],"children":[{"_type":"span","marks":[],"text":"She went on to describe the “substantial” clinical impact of this research, highlighting evidence of a reduced risk of cirrhosis progression with metabolic surgery and the potential implications of these findings for liver transplant eligibility in patients who eventually reach decompensated cirrhosis but otherwise may not have been eligible for transplant due to their weight.","_key":"5fa2538c0a2f"}]},{"_key":"08753b192972","markDefs":[],"children":[{"_type":"span","marks":[],"text":"“As physicians, we're always trying to push boundaries and find the next best thing to help our patients,” Laique said.","_key":"86b103830b2f"}],"_type":"block","style":"normal"},{"_key":"9b7796befd99","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Looking ahead to research she would like to see conducted in the future, Laique highlighted the need for studies assessing the safety and efficacy of metabolic surgery in patients with severe obesity who have cirrhosis and clinically significant portal hypertension; studies comparing medical therapies with surgical weight loss; and studies exploring metabolic surgery’s potential impact on cirrhosis regression.","_key":"5d08eaa10e04"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"c3909a070a0e","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"References","_key":"859a2b3d2ada"}]},{"children":[{"marks":["sup"],"text":"Brooks A. Resmetirom (Rezdiffra) Receives Historic FDA Approval for Noncirrhotic NASH. ","_key":"52a9b3998ff8","_type":"span"},{"_type":"span","marks":["em","sup"],"text":"HCPLive","_key":"2ab1e8213d0f"},{"_type":"span","marks":["sup"],"text":". March 14, 2024. Accessed February 3, 2025. ","_key":"fbd783c8641c"},{"_type":"span","marks":["27818a4691e9","sup"],"text":"https://www.hcplive.com/view/resmetirom-rezdiffra-receives-historic-fda-approval-for-noncirrhotic-nash","_key":"00c4b24689a1"}],"level":1,"_type":"block","style":"normal","_key":"64d0c31c2534","listItem":"number","markDefs":[{"_key":"27818a4691e9","nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/resmetirom-rezdiffra-receives-historic-fda-approval-for-noncirrhotic-nash"}]},{"_type":"block","style":"normal","_key":"9f5b6049a399","listItem":"number","markDefs":[{"href":"https://www.hcplive.com/view/metabolic-surgery-improves-long-term-liver-outcomes-mash-related-cirrhosis","_key":"932a1bb58361","nofollow":true,"blank":true,"_type":"link"}],"children":[{"_type":"span","marks":["sup"],"text":"Brooks A. Metabolic Surgery Improves Long-Term Liver Outcomes in MASH-Related Cirrhosis. ","_key":"5cf3d1db57d7"},{"text":"HCPLive","_key":"56c7d7808649","_type":"span","marks":["em","sup"]},{"marks":["sup"],"text":". January 28, 2025. Accessed February 3, 2025. ","_key":"f1e60a495ea8","_type":"span"},{"text":"https://www.hcplive.com/view/metabolic-surgery-improves-long-term-liver-outcomes-mash-related-cirrhosis","_key":"cc51ad1512f2","_type":"span","marks":["932a1bb58361","sup"]}],"level":1}],"title":"Metabolic Surgery’s Benefit for MASH-Related Cirrhosis, with Soba Laique, MD","contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"_createdAt":"2025-02-04T16:14:31Z","summary":"Laique reviews data supporting the use of metabolic surgery in patients with obesity and cirrhotic MASH.","is_visible":true,"url":{"current":"metabolic-surgery-benefit-mash-related-cirrhosis-soba-laique-md","_type":"slug"},"thumbnail":{"asset":{"extension":"png","metadata":{"palette":{"muted":{"background":"#aa7d63","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":6.47},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":7.27,"background":"#d6ab91"},"darkVibrant":{"title":"#fff","population":0.18,"background":"#150c04","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"population":0.18,"background":"#d7bbb1","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"background":"#c4967b","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":5.48},"dominant":{"title":"#fff","population":7.27,"background":"#d6ab91","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"_type":"sanity.imagePalette","darkMuted":{"background":"#4d3d37","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":2.25}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAAUCAYAAACNiR0NAAAACXBIWXMAABYlAAAWJQFJUiTwAAAE8klEQVR4nD2TZ1dUVxiF5y8oM5RhgBlGepWmCaiAAlEQLARFkSVF6UVFqXZUNDBA1BgdsrIQEylBTQGJSlBBiLRkiXQRBmn28geerHNd5MNe98O957l77/O+sk+fPiH08eNHPnz4wPv373n79i1v3rzh5cuXTBsMjAwP09/fR39/P4ODgzx79oypqSlmZmaYn5+Xvnv9+rV0TiZAizChd+/e8erVKyYmntHW9hdVej3FJ46TeyiHwoJ8zn9byZ8tLQwPD/PixQtmZ2dZWFiQzgiobBG0CBPOxkZHqbl6lcSEBPz8fHFzccbV2ZHl7q74r/YjJTmJutpahgYHJejc3JzkUkBlIqKQgAnL4mVzUxO7YmKws1mGuZkpSlMTLC3M0VpbYa22xMnRnthdMTQ01DM+Pi65FOeEU9kiSDgTGhoa5NzZElb7rsTHxY7gle74ebjg7GCDva0WrdoSpZkJzk6O5Ofl0dPTLXUpoKJP2SJI5Bd/aGtrZU9CHEG+nuTuCqOqcC9nM2PZERqIt5sjWrUF5mbCsYqoqCiam5swGAz/Q2UCJLKLDkQf9fW1bA4PZXuwLzVHkumuLqGr+ht+PJZFXMQ6PBxtsDQ3w9TEmAB/f6qrq6XY4qyQTLgSVsXz+fPn6PWXCQsOJDE8gKr8vTRVFNF9TUfb5ZOUZsUSHbKKFS52WJqb4u3lSblOx9OnA5JLMUoyUeZiqUNDQ5SVnmNTsD8Hozdw6WA8146mce98Ic1lB7lwYDdH47eQHBHICqdl0u0fPXKE3t5eyczExAQykV2ap5kZ+vp6OVKUz/YNAVRmx3CnsoD7Fw/TcbGAO2UHuHE6i9pjqZSnRbHJ1x1Xe1vSU1N48OC+NOxCMgGbnp6W1N7+kKz0FCKDVnElL5F/as4xeL2MvqoTPLpQyGP9cdovHUafE0t0gBcuNtZERW7l1s2bjIyMSF3KBEjkn5ycpOV2Mzujt/OFmzNFcZt5cLGQf/UneHy+iHbdIbouFNJafoiSPVsI8XJCa2FOYIA/ev0VBp48YWxsDNlimSL/jcZf2BgWirWlBTuCv6ThWBKdpTl0FGfTejyNu6fT+bkgnvivfLGxVGKskOPt5cGZ08XSPEpA0aGQcFhfV8v6kBBUZmas8XCiImMb7bocusvzaSvJ4tbRRM4mhhPg7oCx3AiFXI6rixN5hw7S1dUpMWRiBoUEtK72OiFB61AplTgv05AdFUxL2X6pw3tl+/hh/zbSQn1xtbZEbmSEiUKBk4M92VkZElAabLEln3d4lp9qagj0X4OFUom9xoqEsNXcOJVCx3f5/FqcTGVyBLvXeuFopUJhJMdYocDezpaM9FS6Ojs/7/Li6o2Pj1Gh0+Ht6YnS1BRnrZqkjWu4dSaFv/WF3C3P5mpuDJnhq3HXqjGWKzBauhStRk1K0l4ePer4vMti5QyGKZr++J3YmBjUVlaYmZjgaadl39a13Nbt48n1EvprTnK7NJOCHSF42Ggkh0uXLEGr0ZCRlkr7w/sYpiaRzc/PMTDwhFPFJ1nu5ib1olapWOXmQOHO9bSez2WksYKhhjLuVOSQHbkOB7WF1KGIvMLHh5LTp+h53MXk8wnhcIHenm4y09Ow1mikG3a2syXIx50TcRE8/L6I0cZKhup1/HY2m9gQP6zNlRjL5VioVER9HUljQx3joyPMzc7yHxzqK72BC6VTAAAAAElFTkSuQmCC","dimensions":{"_type":"sanity.imageDimensions","width":954,"aspectRatio":1,"height":954},"isOpaque":true,"blurHash":"erK-OV%M?wWV^*-=j[xaWBIUtRWBn$jsRjxuofWBoLWBxuWBM|jsay","_type":"sanity.imageMetadata"},"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png","path":"images/0vv8moc6/hcplive/2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954.png","size":883140,"_id":"image-2248f728d398ad1f6b36b4acacd5f774de3ddd8c-954x954-png","originalFilename":"Screenshot 2025-02-03 at 4.36.36 PM.png","uploadId":"9W9hqAI2rBOQorqLJfI1dGblLtyVl6IK","_rev":"AZG4d7dr4f1zTkdBOCSMTd","_type":"sanity.imageAsset","sha1hash":"2248f728d398ad1f6b36b4acacd5f774de3ddd8c","_updatedAt":"2025-02-03T21:38:24Z","mimeType":"image/png","assetId":"2248f728d398ad1f6b36b4acacd5f774de3ddd8c","_createdAt":"2025-02-03T21:38:24Z"}},"_rev":"LiNg01xkPS3ZVUD07Nlpt6","_updatedAt":"2025-02-05T11:00:07Z"}],"podcastsData":[{"title":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","taxonomyMapping":[{"_ref":"d9a8cdb1-b21c-45a1-a1b4-0f2e14d4c5f9","_type":"reference","_key":"f9425b5cd5b8"},{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"b04d1bf0551f"},{"_type":"reference","_key":"967ba4caac8b","_ref":"84524156-7b84-4e11-841f-e7a6e0f43d74"},{"_ref":"topic_dermatology","_type":"reference","_key":"a650e5df61f9"},{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference","_key":"019acde87612"},{"_ref":"6693c91c-812d-4480-a9bc-4deb0db0d7aa","_type":"reference","_key":"d99130f704d0"}],"link":"/view/skin-of-color-savvy-news-update-addressing-disparities-black-history-month-mentorship-opportunities","articleType":"News","_createdAt":"2025-02-18T18:29:47Z","authorMapping":[{"_ref":"823b6f70-ee21-42b4-8c83-8a2387b79262","_type":"reference","_key":"95c872e82402"},{"_type":"reference","_key":"6b40cbd3c799","_ref":"50390873-f609-4f23-b2f5-a613c054c1ac"}],"_updatedAt":"2025-02-18T21:18:37Z","url":{"current":"skin-of-color-savvy-news-update-addressing-disparities-black-history-month-mentorship-opportunities","_type":"slug"},"_type":"article","display_summary":true,"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"summary":"The February 18, 2025 SOCS News Update highlights SOCS mentorship opportunities as well as the importance of mentors and role models.","ExcludeFromPubMedXML":false,"documentGroup":null,"seoTag":["SOCS","skin of color","Skin of Color Savvy"],"body":[{"children":[{"_type":"span","marks":["strong"],"text":"Welcome to","_key":"f9d0c3c6b939"},{"_type":"span","marks":[],"text":" ","_key":"1eab3a2493f9"},{"_type":"span","marks":["strong","em","ce88edcf2b4d"],"text":"Skin of Color Savvy: The Art and Science of Treating Patients of Color","_key":"dabe9bfe6423"},{"_type":"span","marks":["strong","em"],"text":"!","_key":"acbaa85621c8"}],"_type":"block","style":"h4","_key":"434ee627b0dc","markDefs":[{"href":"https://www.hcplive.com/podcasts/socs-podcast","_key":"ce88edcf2b4d","_type":"link"}]},{"disableAutoPlayVideo":false,"source":"brightcove","_key":"67ab3135d07f","videoObject":{"videoTitle":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","thumbnail":{"_type":"image","asset":{"_ref":"image-5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642-jpg","_type":"reference"}},"videoDuration":"PT10M30S","videoDescription":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","_type":"videoDetails"},"_type":"video","videoID":"6369009365112"},{"style":"normal","_key":"b06eb688b00e","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/","_key":"dbcd0607488e"}],"children":[{"_type":"span","marks":[],"text":"In this News Update, part of the ","_key":"d83bec4493fd"},{"_type":"span","marks":["em"],"text":"Skin of Color Savvy: The Art and Science of Treating Patients of Color ","_key":"d29fd44d097e"},{"_type":"span","marks":[],"text":"series, Brittany Oliver, MD, FAAD, speaks about the pivotal role of mentorship in dermatology and the initiatives led by the ","_key":"2bc0a51fad0e"},{"_type":"span","marks":["dbcd0607488e"],"text":"Skin of Color Society (SOCS)","_key":"2dd459aa9c87"},{"_type":"span","marks":[],"text":" to foster professional development. Oliver emphasizes the profound impact of mentorship on career trajectories, highlighting how meaningful mentor-mentee relationships extend beyond networking to shape clinical expertise, confidence, and leadership in the field.","_key":"e67f647c971c"}],"_type":"block"},{"_key":"ad0936f3e306","markDefs":[{"_key":"b1ea10a929aa","nofollow":true,"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/what-we-do/mentorship/observership-grant"},{"_key":"9e9490fbdf70","nofollow":true,"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/what-we-do/mentorship/mentorship-program"}],"children":[{"marks":[],"text":"She discusses SOCS’s commitment to mentorship as one of its core pillars, detailing key programs such as the ","_key":"d777f16c90a1","_type":"span"},{"text":"SOCS Mentorship Program","_key":"0ff7853312f7","_type":"span","marks":["9e9490fbdf70"]},{"_type":"span","marks":[],"text":", the ","_key":"bab825e31dbc"},{"_type":"span","marks":["b1ea10a929aa"],"text":"Observership Grant","_key":"3de44fdccc5e"},{"marks":[],"text":", and the newly launched Diversity in Clinical Research Mentorship Program. These initiatives aim to support early-career dermatologists, underrepresented minority (URM) investigators, and students pursuing careers in dermatology.","_key":"a9ca05c21705","_type":"span"}],"_type":"block","style":"normal"},{"children":[{"_type":"span","marks":[],"text":"In honor of Black History Month, Oliver reflects on the influential mentors who shaped her journey, including Adam Friedman, MD, and SOCS founder Susan Taylor, MD, whose dedication to mentorship and advocacy has left a lasting impact on the specialty. She also shares her perspective on the importance of increasing diversity in medicine, encouraging dermatologists to engage in outreach, advocacy, and structural changes to address healthcare disparities.","_key":"7f615781e171"}],"_type":"block","style":"normal","_key":"8cc74dd8c14f","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"Finally, in recognition of American Heart Month, the discussion turns to the intersection of dermatology and cardiovascular disease, particularly within communities of color. Oliver underscores the need for systemic solutions, early pipeline programs, and physician-led advocacy to improve representation and access to care. She calls on her colleagues to take an active role in addressing disparities, emphasizing the power of physicians to effect meaningful change beyond the clinic.","_key":"2a3fde89a733"}],"_type":"block","style":"normal","_key":"a3adaf4c0f21","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"To learn more about SOCS’s mentorship programs and initiatives, visit ","_key":"51e682970cf7"},{"_type":"span","marks":["89fe9163ac80"],"text":"Skin of Color Society","_key":"95bd4dee2d3f"},{"_type":"span","marks":[],"text":".","_key":"58358f10b8f8"}],"_type":"block","style":"normal","_key":"590154abb6f7","markDefs":[{"_type":"link","href":"https://www.skinofcolorsociety.org","_key":"89fe9163ac80"}]}],"_rev":"Fd1jDX9jbPHQLM4ybidhou","_id":"0d93cfd0-4dbd-4134-ae47-9525a0ee8193","thumbnail":{"_type":"mainImage","alt":"Skin of Color Savvy: News Update—Addressing Disparities, Black History Month, \u0026 Mentorship Opportunities","asset":{"_ref":"image-5b991868daab2ad6287b75ffd968ecd8e44181a7-4176x2642-jpg","_type":"reference"}},"is_visible":true,"published":"2025-02-18T21:00:45.259Z"},{"documentGroup":null,"title":"The Medical Sisterhood: Men, Medicine, and Their Female Mentors","articleType":"News","is_visible":true,"taxonomyMapping":[{"_key":"8a998e80047b","_ref":"b4e75d36-531d-4379-bd58-ff7f3b5ba3f8","_type":"reference"},{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"3817302caee2"},{"_type":"reference","_key":"afcd7f7b015c","_ref":"703a1bdf-1645-43ac-9e1b-55e382091532"},{"_ref":"84524156-7b84-4e11-841f-e7a6e0f43d74","_type":"reference","_key":"43bcba3f5988"},{"_key":"df39be58a16b","_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference"},{"_ref":"topic_dermatology","_type":"reference","_key":"130e67b39cff"}],"summary":"In this episode, James Q. Del Rosso, DO, joins The Medical Sisterhood for a conversation about empowerment and the benefits of female role models.","published":"2025-02-17T15:00:00.000Z","_createdAt":"2025-02-15T21:26:05Z","_rev":"cID2mV6fSdv64jOtmIZY2i","body":[{"style":"h3","_key":"50acbc5aa284","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/podcasts/the-medical-sisterhood","_key":"499400732db0"}],"children":[{"_type":"span","marks":["strong"],"text":"Welcome to ","_key":"a28f77ad8800"},{"marks":["499400732db0","strong"],"text":"The Medical Sisterhood","_key":"846f4948e78a","_type":"span"},{"text":"!","_key":"95f7e8cb1527","_type":"span","marks":["strong"]}],"_type":"block"},{"videoObject":{"videoDuration":"PT27M25S","videoDescription":"The Medical Sisterhood: White Coats \u0026 Wingmen—How Men Can Uplift Women in Medicine","_type":"videoDetails","videoTitle":"The Medical Sisterhood: White Coats \u0026 Wingmen—How Men Can Uplift Women in Medicine","thumbnail":{"_type":"image","asset":{"_ref":"image-f81770312840bfdf57d9d5ab4423dde0f4be7f78-1200x1200-png","_type":"reference"}}},"_type":"video","videoID":"6368844108112","disableAutoPlayVideo":false,"source":"brightcove","_key":"d8aeee7001a2"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"In the latest episode of ","_key":"c67688050640"},{"_type":"span","marks":["em"],"text":"The Medical Sisterhood","_key":"1af724d92c1e"},{"_type":"span","marks":[],"text":", host Mona Shahriari, MD, an assistant clinical professor of dermatology at the Yale University School of Medicine and the associate director of clinical trials at Central Connecticut Dermatology Research, spoke alongside James Q. Del Rosso, DO, research director of JDR Dermatology Research and president of the American Acne and Rosacea Society, to discuss the empowerment of women in medicine, the impact of male and female role models for clinicians, and more.","_key":"09638af3dcdf"}],"_type":"block","style":"normal","_key":"8261e7767972"},{"content":[{"style":"normal","_key":"c558a39dcc63","markDefs":[],"children":[{"marks":["strong"],"text":"0:00 Introduction of James Del Rosso, DO","_key":"2a4298907bf9","_type":"span"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"01:37 Early experiences in medical school","_key":"b1179618c55c"}],"_type":"block","style":"normal","_key":"4c3b0736f0a9"},{"_type":"block","style":"normal","_key":"ad8f3136f2fc","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"04:16 Female role models and childhood experiences","_key":"59dc6111df63"}]},{"_key":"daf334c7772e","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"11:24 Aunt's role in impacting the world","_key":"e52f3154cbcf"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"text":"12:27 Societal pressures for women","_key":"d57daad1ec5e","_type":"span","marks":["strong"]}],"_type":"block","style":"normal","_key":"cf1896ddbb26"},{"markDefs":[],"children":[{"marks":["strong"],"text":"14:46 Experiences as a male in medicine","_key":"7ff63a14b2d6","_type":"span"}],"_type":"block","style":"normal","_key":"68daa29319e1"},{"style":"normal","_key":"b59f82f672e3","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"19:47 Closing messages","_key":"7c0462f90c6c"}],"_type":"block"},{"_type":"block","style":"normal","_key":"dd54d0023be2","markDefs":[],"children":[{"marks":["strong"],"text":"25:51 Perspectives on life","_key":"718d257e11b8","_type":"span"}]},{"markDefs":[],"children":[{"text":"26:57 Conclusion ","_key":"dcdd95df42ce","_type":"span","marks":["strong"]}],"_type":"block","style":"normal","_key":"924adafa7106"}],"_type":"sidebar","caption":"Key Highlights","_key":"19e9d071cc25"},{"_type":"block","style":"normal","_key":"3605e362d8f1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"After introducing Del Rosso, Shahriari highlighted her friendship with Del Rosso and their careers in the field of dermatology. She asked Del Rosso to discuss various elements of his extensive career in dermatology and his journey toward becoming a clinician. Del Rosso described his family’s history, including his own Italian-American heritage and his early life in Brooklyn, New York. Del Rosso noted his own access to an array of intelligent role models in his youth, with both male and female figures helping him to shape his future.","_key":"52707ecf0145"}]},{"children":[{"_type":"span","marks":[],"text":"Del Rosso touched on various elements of his early career, pointing to his own choices regarding choosing a medical school that fit both his academic and financial needs. He expressed satisfaction at his choice to attend Ohio University Heritage College of Osteopathic Medicine over other academic institutions, highlighting his positive experiences with such figures as Wilma Bergfeld, MD.","_key":"ef58ba8501d2"}],"_type":"block","style":"normal","_key":"41bb3e498c8a","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Over the course of the episode, the conversation shifted to the unique benefits of having had a variety of influential female role models in one’s younger years. Del Rosso noted that, as a young person, his mother, aunts, and grandparents all set strong examples for him. Shahriari spoke with Del Rosso about his familial history prior to his career in dermatology. Specifically, she spoke to Del Rosso about the profound role his aunt and sister had in his life and in helping to shape him as an individual.","_key":"5c50b968e54f"}],"_type":"block","style":"normal","_key":"84c65e4ecd06"},{"markDefs":[],"children":[{"marks":[],"text":"The discussion between Shahriari and Del Rosso further evolved into a conversation regarding pressures faced by women in the field of dermatology and the empowerment of female colleagues by male allies. Del Rosso commented on his own challenges in persevering throughout his career in medicine. The conversation was punctuated with a point about resilience in one's own career, continuing to move forward regardless of the varying opinions and views of others.","_key":"71a44e1e95e6","_type":"span"}],"_type":"block","style":"normal","_key":"5df783fb71e8"},{"_type":"block","style":"normal","_key":"399468556c33","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Tune in monthly on ","_key":"9f687175575a"},{"_type":"span","marks":["em"],"text":"HCPLive","_key":"ef80cdf36b2e"},{"_type":"span","marks":[],"text":" for empowering conversations that will help you build a fulfilling career and life! All episodes of The Medical Sisterhood will be available in a video format via HCPLive.com, with audio-only version available via Apple and Spotify.","_key":"2d3c03b80ddf"}]},{"style":"normal","_key":"61bec9e341a9","markDefs":[{"_type":"link","href":"https://www.linkedin.com/groups/13095556/","_key":"629061328ce3","nofollow":true,"blank":true}],"children":[{"_type":"span","marks":["629061328ce3","strong"],"text":"Want to join The Medical Sisterhood community? Click here to join our LinkedIn Group!","_key":"bb236d09cbd1"}],"_type":"block"},{"_key":"8449d2318449","markDefs":[],"children":[{"marks":["em"],"text":"Editor's note: This summary was created with the help of artificial intelligence.","_key":"28620f8a4b5d","_type":"span"}],"_type":"block","style":"normal"}],"url":{"current":"the-medical-sisterhood-white-coats-wingmen-how-men-can-uplift-women-in-medicine","_type":"slug"},"authorMapping":[{"_ref":"c0271bed-fd84-49b6-9126-a82acb3be026","_type":"reference","_key":"2e3a739caef1"},{"_ref":"89b46644-6ed6-4741-89aa-02b6fc83ce8d","_type":"reference","_key":"c3bd7b8ae148"}],"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"seoTag":["Medical Sisterhood"],"link":"/view/the-medical-sisterhood-white-coats-wingmen-how-men-can-uplift-women-in-medicine","_type":"article","ExcludeFromPubMedXML":false,"display_summary":true,"_id":"dae00c38-f11a-486f-af2f-7ccb26302816","_updatedAt":"2025-02-18T17:54:51Z","thumbnail":{"_type":"mainImage","alt":"Medical Sisterhood: James Del Rosso, DO","asset":{"_ref":"image-48a42c96bb84d8067d9522bd8af433c69b4dea94-1200x1200-png","_type":"reference"}}},{"articleType":"News","ExcludeFromPubMedXML":false,"_updatedAt":"2025-02-15T18:35:12Z","summary":"In this episode, hosts offer perspective on recent studies assessing insulin delivery systems in adults with type 2 diabetes.","thumbnail":{"_type":"mainImage","alt":"Default thumbnail for Diabetes Dialogue, featuring podcast logo and headshots of hosts.","asset":{"_ref":"image-d42a1dd1026ec814a638db483eb5d988a0fe6cc5-552x622-png","_type":"reference"}},"body":[{"_key":"2c3aba32eab2","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/podcasts/diabetes-dialogue","_key":"299f183b6193"}],"children":[{"marks":["strong"],"text":"Welcome back to","_key":"1fca95473596","_type":"span"},{"_key":"c2c42d1223b4","_type":"span","marks":[],"text":" "},{"_type":"span","marks":["299f183b6193","strong","em"],"text":"Diabetes Dialogue: Technology, Therapeutics, \u0026 Real-World Perspectives!","_key":"140e97751ee8"}],"_type":"block","style":"normal"},{"_key":"6edaad935a1c","videoObject":{"_type":"videoDetails","videoTitle":"Diabetes Dialogue: Omnipod 5 and Medtronic 780G for Type 2 Diabetes","thumbnail":{"_type":"image","asset":{"_ref":"image-b62cf5d89615a8366f53836641b26341eb29482a-5333x3000-png","_type":"reference"}},"videoDuration":"PT14M58S","videoDescription":"Diabetes Dialogue: Omnipod 5 and Medtronic 780G for Type 2 Diabetes"},"_type":"video","videoID":"6368854913112","disableAutoPlayVideo":false,"source":"brightcove"},{"markDefs":[{"_type":"link","href":"https://www.hcplive.com/clinical/type-2-diabetes","_key":"77850925a8b9"}],"children":[{"marks":[],"text":"In this episode of ","_key":"f5192e3e1dbd","_type":"span"},{"text":"Diabetes Dialogue: Technology, Therapeutics, \u0026 Real-World Perspectives","_key":"7d39c23523d5","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":", hosts Diana Isaacs, PharmD, an endocrine clinical pharmacist, director of Education and Training in Diabetes Technology, and codirector of Endocrine Disorders in Pregnancy at the Cleveland Clinic, and Natalie Bellini, DNP, program director of Diabetes Technology at University Hospitals Diabetes and Metabolic Care Center, discuss a pair of recently published studies examining the use of diabetes technology in adults with ","_key":"6657cff1fcbe"},{"_type":"span","marks":["77850925a8b9"],"text":"type 2 diabetes","_key":"4cdc307ee50d"},{"_type":"span","marks":[],"text":".","_key":"981879f97f2a"}],"_type":"block","style":"normal","_key":"04ac714181d9"},{"markDefs":[],"children":[{"_key":"335fc568a0ec","_type":"span","marks":["strong"],"text":"SECURE-T2D"}],"_type":"block","style":"h2","_key":"826ffb4b772c"},{"_type":"block","style":"normal","_key":"d850d5c65557","markDefs":[],"children":[{"_type":"span","marks":[],"text":"A single-arm prospective study conducted at 21 US clinical centers, SECURE-T2D assessed the impact of automated insulin delivery (AID) on glycemic control in adults with type 2 diabetes using insulin for at least 3 months. The study enrolled 305 participants (mean age, 57 years; 57% female), with a diverse racial and ethnic representation, including 24% Black and 22% Hispanic or Latino.","_key":"9f9fbe52ec81"}]},{"_key":"ab58aeb13271","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Following a 14-day standard therapy phase, participants used the Omnipod 5 AID system for 13 weeks. HbA1c decreased from 8.2% (SD, 1.3) at baseline to 7.4% (SD, 0.9) (mean difference, -0.8 percentage points; 95% CI, -1.0 to -0.7; ","_key":"f447822ef352"},{"_key":"4d4de4089273","_type":"span","marks":["em"],"text":"P"},{"_key":"fb2a0b503161","_type":"span","marks":[],"text":" \u003c.001) and time in range (70-180 mg/dL) increased from 45% (SD, 25) to 66% (SD, 17) (mean difference, 20 percentage points; 95% CI, 18 to 22; "},{"text":"P","_key":"2aa8f7570aef","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":" \u003c.001).","_key":"a9b7131619d4"}],"_type":"block","style":"normal"},{"children":[{"text":"Improvement was observed across subgroups, regardless of concurrent GLP-1 RA or SGLT2 inhibitor use or pretrial insulin regimen. Rates of hypoglycemia remained noninferior to standard therapy, with one severe hypoglycemia event and no cases of diabetic ketoacidosis or hyperosmolar hyperglycemic syndrome. Findings suggest AID may be a safe and effective option for insulin-requiring adults with type 2 diabetes.","_key":"aaa476451f8f","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"7f969e02b31d","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Medtronic 780G in Type 2 Diabetes","_key":"b0d5bef94e26"}],"_type":"block","style":"h2","_key":"8ac1dc9edb06"},{"_key":"b4abf0ade363","markDefs":[],"children":[{"_key":"cca848c9f9bc","_type":"span","marks":[],"text":"A 13-site, single-arm, open-label study evaluated the safety and effectiveness of the MiniMed™ 780G advanced hybrid closed-loop (AHCL) system in 95 adults with insulin-requiring type 2 diabetes. Over the 90-day study period, mean HbA1c decreased from 7.9% (SD, 1.0%) to 7.2% (SD, 0.7%) (P \u003c 0.001), and the percentage of time in range of 70 to 180 mg/dL) reached 80.9% (95% CI, 78.4% to 83.1%)."}],"_type":"block","style":"normal"},{"style":"normal","_key":"b73ff6e6a0a6","markDefs":[],"children":[{"text":"Total daily insulin dose increased from 77.4 U (SD, 38.5) to 91.8 U (SD, 49.3) (","_key":"34c96333decb","_type":"span","marks":[]},{"_type":"span","marks":["em"],"text":"P","_key":"c02e86e8aa56"},{"_type":"span","marks":[],"text":"\u003c.0001), while carbohydrate intake remained stable, and user-initiated boluses decreased. Investigators pointed out no significant changes in participant weight or body mass index were observed during the study and there were no reports of severe hypoglycemia, diabetic ketoacidosis, hyperosmolar hyperglycemic state, or serious adverse events.","_key":"b29719a33f93"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Relevant disclosures for Isaacs include Eli Lilly and Company, Novo Nordisk, Sanofi, Abbott Diabetes Care, Dexcom, Medtronic, and others. Relevant disclosures for Bellini include Abbott Diabetes Care, MannKind, Provention Bio, and others.","_key":"bf3e627f5400"}],"_type":"block","style":"normal","_key":"7657ba2c9045"},{"_type":"block","style":"h6","_key":"afcf16ef99f7","markDefs":[],"children":[{"marks":[],"text":"References:","_key":"7fcc469264d4","_type":"span"}]},{"children":[{"_key":"fb9e7b346273","_type":"span","marks":[],"text":"Pasquel FJ, Davis GM, Huffman DM, et al. Automated Insulin Delivery in Adults With Type 2 Diabetes: A Nonrandomized Clinical Trial. "},{"text":"JAMA Netw Open.","_key":"81083a2ac0a6","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":" 2025;8(2):e2459348. doi:10.1001/jamanetworkopen.2024.59348","_key":"3a993802b90e"}],"level":1,"_type":"block","style":"h6","_key":"3b36f6197e7a","listItem":"number","markDefs":[]},{"children":[{"text":"Bhargava A, Bergenstal RM, Warren ML, et al. Safety and Effectiveness of MiniMed™ 780G Advanced Hybrid Closed-Loop Insulin Intensification in Adults with Insulin-Requiring Type 2 Diabetes. ","_key":"83803f41baef","_type":"span","marks":[]},{"text":"Diabetes Technol Ther","_key":"0544bf2dafe6","_type":"span","marks":["em"]},{"text":". Published online February 6, 2025. doi:10.1089/dia.2024.0586","_key":"fc193b25a9bd","_type":"span","marks":[]}],"level":1,"_type":"block","style":"h6","_key":"98a9260d23d5","listItem":"number","markDefs":[]}],"is_visible":true,"documentGroup":null,"published":"2025-02-15T16:12:01.594Z","_createdAt":"2025-02-15T16:11:34Z","url":{"_type":"slug","current":"diabetes-dialogue-omnipod-5-and-medtronic-780g-for-type-2-diabetes"},"_type":"article","link":"/view/diabetes-dialogue-omnipod-5-and-medtronic-780g-for-type-2-diabetes","_id":"039a1938-4959-48ce-88e5-db9505f36a78","contentCategory":{"_createdAt":"2020-07-08T19:29:19Z","_rev":"Rbpfm4lNh9K9vOrCWBt9bd","_type":"contentCategory","name":"Podcasts","_id":"81559818-1ad3-49ad-86c6-f9dbe8242ec6","_updatedAt":"2020-07-08T19:29:19Z"},"title":"Diabetes Dialogue: Omnipod 5 and Medtronic 780G for Type 2 Diabetes","authorMapping":[{"_ref":"659e15b1-c290-41e2-95cf-fcb60336c20a","_type":"reference","_key":"1bdabcdc32f7"},{"_ref":"7f4c7bfb-ca04-4bdd-a6f4-c1360aec4077","_type":"reference","_key":"7fa800bf22f1"}],"taxonomyMapping":[{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"b4bef95e25cb"},{"_key":"76ff56ebbacd","_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},{"_key":"f5c2a481078c","_ref":"0b42f38c-7a65-4bb4-ac2d-86500db18ab8","_type":"reference"},{"_ref":"topic_endocrinology","_type":"reference","_key":"38e78301d581"},{"_ref":"51dc89af-5e93-43ab-b61f-16dbe4565ed0","_type":"reference","_key":"b3fedb8912e2"},{"_type":"reference","_key":"bbb2f19c8654","_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc"}],"_rev":"XE9vnGgPXscpvWVDktfes5"},{"body":[{"markDefs":[],"children":[{"marks":["strong","em"],"text":"Welcome to Kidney Compass: Navigating Clinical Trials!","_key":"daadc6027e38","_type":"span"}],"_type":"block","style":"h5","_key":"01bb6a2e7f9b"},{"_type":"video","videoID":"6368721450112","disableAutoPlayVideo":true,"source":"brightcove","_key":"0bdc017f2768","videoObject":{"videoTitle":"Kidney Compass: Applying Hierarchical Composite Endpoints in Kidney Disease Trials","thumbnail":{"_type":"image","asset":{"_ref":"image-86c94cf700fbdec61205ae4b090110efb448acff-800x451-jpg","_type":"reference"}},"videoDuration":"PT9M15S","videoDescription":"Kidney Compass: Applying Hierarchical Composite Endpoints in Kidney Disease Trials","_type":"videoDetails"}},{"style":"normal","_key":"c2b17c3a3d78","markDefs":[],"children":[{"text":"In the final installment of our 4-part episode of ","_key":"d1695122cd73","_type":"span","marks":[]},{"text":"Kidney Compass","_key":"d1af995dd8eb","_type":"span","marks":["em"]},{"marks":[],"text":", hosts Brendon Neuen, MBBS, PhD, and Shikha Wadhwani, MD, MS, are joined by special guests Dustin Little, MD, and Niels Jongs, PhD, as they discuss the application of hierarchical composite endpoints (HCEs) in specific kidney disease subpopulations and rare disease trials.","_key":"be028557f168","_type":"span"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Wadhwani highlights the need to tailor HCEs to disease-specific priorities, such as relapse reduction and immunosuppression minimization in lupus nephritis. The discussion then shifts to subgroup analyses in trials using HCEs. While traditional trials are powered for the overall population, subgroup analyses often lack statistical power. Jongs explains that increasing the efficiency of HCE-powered trials may allow for better-powered subgroup analyses, but achieving statistical certainty in smaller populations remains challenging.","_key":"8539e36f605e"}],"_type":"block","style":"normal","_key":"1247f0cb70bb"},{"_key":"0ae894686ba6","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The panel explores a real-world example of focal segmental glomerulosclerosis (FSGS) within the DAPA-CKD trial, where traditional analyses showed numerical benefits of dapagliflozin but lacked statistical significance due to wide confidence intervals. Jongs and Little discuss how applying HCEs and win odds in these cases could refine statistical assessments and potentially strengthen findings, offering greater confidence in treatment effects.","_key":"349e317042f8"}],"_type":"block","style":"normal"},{"style":"normal","_key":"62a0afd1c133","markDefs":[],"children":[{"marks":[],"text":"The episode concludes with reflections on the future of HCEs in nephrology research, emphasizing their potential to optimize trial efficiency, improve data interpretation, and advance therapies for rare and complex kidney diseases.","_key":"2244fbebd440","_type":"span"}],"_type":"block"},{"children":[{"_type":"span","marks":[],"text":"For ease of viewing, we've divided this episode into 4 sections and highlighted them below.","_key":"460a2d253d7c"}],"_type":"block","style":"normal","_key":"ac186796d431","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Kidney Compass: Hierarchical Composite Endpoints in Nephrology","_key":"0335d923583b"}],"_type":"block","style":"h3","_key":"64962b6d96bf"},{"_type":"block","style":"h4","_key":"aa27ecc17ef3","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-hierarchical-composite-endpoints-nephrology-dustin-little-md-niels-jongs-phd","_key":"2aa91eea597a","nofollow":true}],"children":[{"_type":"span","marks":["2aa91eea597a","strong"],"text":"Part 1: Introductions, HCEs in Nephrology","_key":"d1fcc1252a70"}]},{"_type":"block","style":"h4","_key":"683ed0735d42","markDefs":[{"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-understanding-hces-nephrology-clinical-trials","_key":"f3ee2c399048","nofollow":true,"blank":true}],"children":[{"_type":"span","marks":["f3ee2c399048","strong"],"text":"Part 2: HCEs in Nephrology Clinical Trials","_key":"d79dec449108"}]},{"_type":"block","style":"h4","_key":"3fe791e0224a","markDefs":[{"href":"https://www.hcplive.com/view/kidney-compass-addressing-skepticism-around-hces-nephrology","_key":"ef279f19bd2c","nofollow":true,"blank":true,"_type":"link"}],"children":[{"_type":"span","marks":["ef279f19bd2c","strong"],"text":"Part 3: Addressing HCE Skepticism, Potential Limitations","_key":"8d5ef3ca47c5"}]},{"style":"h4","_key":"9dffbe285b79","markDefs":[{"_key":"66ea5d4253ee","nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-applying-hierarchical-composite-endpoints-kidney-disease-trials"}],"children":[{"_type":"span","marks":["66ea5d4253ee","strong"],"text":"Part 4: Applying HCEs in Kidney Disease Trials","_key":"a2373e23227c"},{"_type":"span","marks":[],"text":" ","_key":"4860ae979040"},{"_type":"span","marks":["strong"],"text":"(Current Segment)","_key":"8250cd25898c"}],"_type":"block"},{"_key":"7b359f4fb61f","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Relevant disclosures for ","_key":"541a77e024ab"},{"text":"Neuen","_key":"1513293cbc90","_type":"span","marks":["strong","em"]},{"_type":"span","marks":["em"],"text":" include AstraZeneca, Bayer, Boehringer and Ingelheim, Janssen, and others. Relevant disclosures for ","_key":"57df65aed87f"},{"_key":"60c9da780d03","_type":"span","marks":["strong","em"],"text":"Wadhwani"},{"_type":"span","marks":["em"],"text":" include the National Institute of Diabetes and Digestive and Kidney Diseases, GSK, Calliditas, and Travere Therapeutics. Relevant disclosures for ","_key":"4dad24f24800"},{"_type":"span","marks":["strong","em"],"text":"Little","_key":"a1fad3c38bfc"},{"_type":"span","marks":["em"],"text":" include AstraZeneca.","_key":"4e7cb537a9ea"}],"_type":"block","style":"normal"}],"ExcludeFromPubMedXML":false,"thumbnail":{"asset":{"_ref":"image-513a7a8843e2e6442581970b54b4ddc278e6628c-300x300-png","_type":"reference"},"_type":"mainImage","alt":"Kidney Compass: Navigating Clinical Trials"},"url":{"current":"kidney-compass-applying-hierarchical-composite-endpoints-kidney-disease-trials","_type":"slug"},"_updatedAt":"2025-02-13T01:03:01Z","_type":"article","taxonomyMapping":[{"_type":"reference","_key":"66e0c3650e73","_ref":"00c35849-3d97-4901-be93-6e229c2a844d"},{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference","_key":"58e350d36188"},{"_ref":"topic_nephrology","_type":"reference","_key":"a7cdadcb4d6c"},{"_ref":"23e43f09-f248-4adb-a02b-7704fb3aa4d3","_type":"reference","_key":"4afa22d2b024"},{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference","_key":"635d3c365b52"},{"_key":"acbd89131e17","_ref":"207059b8-dd60-459e-b64b-762f1310f280","_type":"reference"}],"contentCategory":{"_id":"81559818-1ad3-49ad-86c6-f9dbe8242ec6","_updatedAt":"2020-07-08T19:29:19Z","_createdAt":"2020-07-08T19:29:19Z","_rev":"Rbpfm4lNh9K9vOrCWBt9bd","_type":"contentCategory","name":"Podcasts"},"articleType":"News","documentGroup":null,"authorMapping":[{"_key":"ee08ebce6993","_ref":"180837f8-dff6-4398-b243-f1b5de0f9362","_type":"reference"},{"_type":"reference","_key":"449ce7709573","_ref":"0bc0864f-1d0a-44de-9fb3-be261eec4abc"}],"is_visible":true,"title":"Kidney Compass: Applying Hierarchical Composite Endpoints in Kidney Disease Trials","_createdAt":"2025-02-12T20:52:52Z","link":"/view/kidney-compass-applying-hierarchical-composite-endpoints-kidney-disease-trials","_id":"268e8ae9-6867-4f5c-9dc7-5c6d81170b07","summary":"In the final segments of this 4-part episode, the discussion focuses on the use of HCEs in different kidney disease trials.","published":"2025-02-13T01:03:00.732Z","_rev":"NT4ETOVf4DRHVmw797FFWe"},{"_createdAt":"2025-02-12T20:42:58Z","title":"Kidney Compass: Addressing Skepticism Around HCEs in Nephrology","is_visible":true,"ExcludeFromPubMedXML":false,"articleType":"News","authorMapping":[{"_ref":"180837f8-dff6-4398-b243-f1b5de0f9362","_type":"reference","_key":"bf1a54b19edd"},{"_ref":"0bc0864f-1d0a-44de-9fb3-be261eec4abc","_type":"reference","_key":"f4a046a0f462"}],"_rev":"NT4ETOVf4DRHVmw797FAiu","_type":"article","taxonomyMapping":[{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"142b45747c54"},{"_type":"reference","_key":"d73779705c27","_ref":"703a1bdf-1645-43ac-9e1b-55e382091532"},{"_type":"reference","_key":"153acafca321","_ref":"topic_nephrology"},{"_type":"reference","_key":"30ba478870bb","_ref":"23e43f09-f248-4adb-a02b-7704fb3aa4d3"},{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference","_key":"749b306b3bc3"},{"_key":"1df071ebdc38","_ref":"207059b8-dd60-459e-b64b-762f1310f280","_type":"reference"}],"summary":"In part 3 of 4 from this episode, the discussion focuses on potential limitations to HCEs and addressing skepticism around their use in nephrology.","body":[{"_key":"40a065221a64","markDefs":[],"children":[{"_key":"ad4fe089496f","_type":"span","marks":["strong","em"],"text":"Welcome to Kidney Compass: Navigating Clinical Trials!"}],"_type":"block","style":"h5"},{"disableAutoPlayVideo":true,"source":"brightcove","_key":"5edd20f5f30b","videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-86c94cf700fbdec61205ae4b090110efb448acff-800x451-jpg","_type":"reference"}},"videoDuration":"PT16M02S","videoDescription":"Kidney Compass: Addressing Skepticism Around HCEs in Nephrology","_type":"videoDetails","videoTitle":"Kidney Compass: Addressing Skepticism Around HCEs in Nephrology"},"_type":"video","videoID":"6368720770112"},{"markDefs":[],"children":[{"marks":[],"text":"In the third installment of our 4-part episode of ","_key":"dc68c0d9ff76","_type":"span"},{"_type":"span","marks":["em"],"text":"Kidney Compass","_key":"bf85002b817b"},{"_key":"b116c4741c56","_type":"span","marks":[],"text":", hosts Brendon Neuen, MBBS, PhD, and Shikha Wadhwani, MD, MS, are joined by special guests Dustin Little, MD, and Niels Jongs, PhD, as they discuss the implications of hierarchical composite endpoints (HCEs) for kidney disease trials, regulatory considerations, and patient-centered outcomes."}],"_type":"block","style":"normal","_key":"1179e111f618"},{"_type":"block","style":"normal","_key":"7b3fc57ae514","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Wadhwani raises concerns about fixed follow-up requirements in clinical trials, particularly when studies are terminated early due to efficacy, as seen in the FLOW and DAPA-CKD trials. Jongs explains how follow-up variability can be statistically managed by adjusting pairwise comparisons to a minimum follow-up period, ensuring fair assessment across different trial durations. While acknowledging theoretical concerns, he emphasizes that empirical analyses suggest this approach does not significantly alter trial conclusions.","_key":"eaf2890eb4b2"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The conversation then shifts to skepticism surrounding HCEs, including how event prioritization is determined and how win odds should be interpreted. Little highlights the flexibility of HCEs, noting that they incorporate only validated clinical and surrogate endpoints, making them suitable for regulatory approval.","_key":"51385f07bf9f"}],"_type":"block","style":"normal","_key":"030e70adab40"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"A key advantage of HCEs, the panel agrees, is their ability to enhance statistical power, potentially reducing required sample sizes—an especially critical benefit for rare kidney diseases. Wadhwani and Little further explore the potential to integrate patient-reported outcomes, such as symptom burden and quality of life, into HCE frameworks. While acknowledging the complexity of arranging hierarchies that blend clinical and PRO measures, they highlight polycystic kidney disease as a prime example where factors like cyst pain and kidney volume could be incorporated alongside traditional renal endpoints.","_key":"54e378c6e803"}],"_type":"block","style":"normal","_key":"51fb4b47a08a"},{"markDefs":[],"children":[{"text":"The episode concludes with a discussion on future applications of HCEs in nephrology. The panel emphasizes that while methodological refinements are ongoing, HCEs offer a promising strategy to improve trial efficiency, capture a broader range of clinically meaningful outcomes, and ultimately accelerate therapeutic advancements for patients with kidney disease.","_key":"1fab3dd8acbb","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"262bf6904bb0"},{"children":[{"_type":"span","marks":[],"text":"For ease of viewing, we've divided this episode into 4 sections and highlighted them below.","_key":"996d7e9e5788"}],"_type":"block","style":"normal","_key":"e13cadfe6028","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"Kidney Compass: Hierarchical Composite Endpoints in Nephrology","_key":"f573ced2eb74"}],"_type":"block","style":"h3","_key":"8477eae25961"},{"children":[{"_type":"span","marks":["f87c8b3b747e","strong"],"text":"Part 1: Introductions, HCEs in Nephrology","_key":"c5ba65876f2e"}],"_type":"block","style":"h4","_key":"14cf3f3d7d0b","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-hierarchical-composite-endpoints-nephrology-dustin-little-md-niels-jongs-phd","_key":"f87c8b3b747e"}]},{"markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-understanding-hces-nephrology-clinical-trials","_key":"9ad73e4f917b"}],"children":[{"_type":"span","marks":["9ad73e4f917b","strong"],"text":"Part 2: HCEs in Nephrology Clinical Trials","_key":"a16e0f8542c2"}],"_type":"block","style":"h4","_key":"b077bf3b0ed9"},{"markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-addressing-skepticism-around-hces-nephrology","_key":"674cea457a43"}],"children":[{"_key":"5b9400b19e53","_type":"span","marks":["674cea457a43","strong"],"text":"Part 3: Addressing HCE Skepticism, Potential Limitations"},{"_type":"span","marks":[],"text":" ","_key":"5c079581eeb4"},{"_key":"215cb0768fa9","_type":"span","marks":["strong"],"text":"(Current Segment)"}],"_type":"block","style":"h4","_key":"e1050e1ba0bb"},{"markDefs":[{"href":"https://www.hcplive.com/view/kidney-compass-applying-hierarchical-composite-endpoints-kidney-disease-trials","_key":"9b281d6e7689","nofollow":true,"blank":true,"_type":"link"}],"children":[{"_type":"span","marks":["9b281d6e7689","strong"],"text":"Part 4: Applying HCEs in Kidney Disease Trials","_key":"7add6ddf3b16"}],"_type":"block","style":"h4","_key":"1b50a802d52d"},{"_type":"block","style":"normal","_key":"5d8ca6c54604","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Relevant disclosures for ","_key":"6e969627a86c"},{"_type":"span","marks":["strong","em"],"text":"Neuen","_key":"4f27283d4907"},{"_type":"span","marks":["em"],"text":" include AstraZeneca, Bayer, Boehringer and Ingelheim, Janssen, and others. Relevant disclosures for ","_key":"7900bdec4430"},{"_type":"span","marks":["strong","em"],"text":"Wadhwani","_key":"207db8099901"},{"_type":"span","marks":["em"],"text":" include the National Institute of Diabetes and Digestive and Kidney Diseases, GSK, Calliditas, and Travere Therapeutics. Relevant disclosures for ","_key":"603feebccba7"},{"_type":"span","marks":["strong","em"],"text":"Little","_key":"ab7e09d46e3f"},{"_type":"span","marks":["em"],"text":" include AstraZeneca.","_key":"54e567cd09ab"}]}],"contentCategory":{"_createdAt":"2020-07-08T19:29:19Z","_rev":"Rbpfm4lNh9K9vOrCWBt9bd","_type":"contentCategory","name":"Podcasts","_id":"81559818-1ad3-49ad-86c6-f9dbe8242ec6","_updatedAt":"2020-07-08T19:29:19Z"},"_updatedAt":"2025-02-13T01:02:01Z","published":"2025-02-13T01:02:09.097Z","_id":"43839b1e-1c11-4a63-9a67-ea9bce14d5f2","url":{"current":"kidney-compass-addressing-skepticism-around-hces-nephrology","_type":"slug"},"thumbnail":{"alt":"Kidney Compass: Navigating Clinical Trials","asset":{"_ref":"image-513a7a8843e2e6442581970b54b4ddc278e6628c-300x300-png","_type":"reference"},"_type":"mainImage"},"link":"/view/kidney-compass-addressing-skepticism-around-hces-nephrology","documentGroup":null},{"_rev":"NT4ETOVf4DRHVmw797Ex3o","_updatedAt":"2025-02-13T01:01:01Z","summary":"In part 2 of 4 from this episode, the discussion focuses on hierarchical composite endpoints and their use in nephrology trials and research.","_type":"article","body":[{"children":[{"text":"Welcome to Kidney Compass: Navigating Clinical Trials!","_key":"a2e133bcc8a5","_type":"span","marks":["strong","em"]}],"_type":"block","style":"h5","_key":"70df17d19bab","markDefs":[]},{"_key":"d42295ed2abe","videoObject":{"_type":"videoDetails","videoTitle":"Kidney Compass: HCEs in Nephrology Clinical Trials","thumbnail":{"asset":{"_ref":"image-86c94cf700fbdec61205ae4b090110efb448acff-800x451-jpg","_type":"reference"},"_type":"image"},"videoDuration":"PT13M27S","videoDescription":"Kidney Compass: HCEs in Nephrology Clinical Trials"},"_type":"video","videoID":"6368718813112","disableAutoPlayVideo":true,"source":"brightcove"},{"_type":"block","style":"normal","_key":"bf17d98f9d48","markDefs":[],"children":[{"marks":[],"text":"In the second installment of our 4-part episode of ","_key":"59c0bbe08bf8","_type":"span"},{"_key":"bc2fd9955d5a","_type":"span","marks":["em"],"text":"Kidney Compass"},{"marks":[],"text":", hosts Brendon Neuen, MBBS, PhD, and Shikha Wadhwani, MD, MS, dive into hierarchical composite endpoints (HCEs) and their potential to refine nephrology clinical trials with special guests Dustin Little, MD, and Niels Jongs, PhD.","_key":"07e40d9b0aa0","_type":"span"}]},{"_key":"251ba45bafa8","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The discussion begins with a breakdown of how HCEs integrate hard clinical endpoints—such as death, dialysis, and significant declines in eGFR—with eGFR slope, creating a more comprehensive measure of disease progression. Little explains how HCEs combine multiple validated endpoints into a single, prioritized hierarchy, after which Jongs describes the statistical framework behind HCEs, detailing how the win odds approach compares all patients in the treatment and control arms to determine overall treatment effect.","_key":"732715e067d7"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The conversation also contrasts win odds with traditional hazard ratios, with the panel noting that while the two metrics align in direction, win odds offer advantages in interpretability and power. Little highlights post hoc analyses of major nephrology trials, demonstrating strong consistency between win odds and hazard ratio-based findings. The panel also discusses the ability of HCEs to increase statistical power and reduce required sample sizes, potentially making trials more efficient without compromising rigor.","_key":"ceda945d988d"}],"_type":"block","style":"normal","_key":"22073752dc98"},{"_type":"block","style":"normal","_key":"3f9479779244","markDefs":[],"children":[{"_type":"span","marks":[],"text":"As the discussion continues, Jongs notes that HCEs could significantly improve trial design efficiency by reducing the number of patients needed to detect meaningful treatment effects. The panel underscores the need for continued refinement and validation of this approach to optimize nephrology clinical research.","_key":"5ee5c8ca1643"}]},{"style":"normal","_key":"eaa935f97272","markDefs":[],"children":[{"_type":"span","marks":[],"text":"For ease of viewing, we've divided this episode into 4 sections and highlighted them below.","_key":"ed8c7b08cc59"}],"_type":"block"},{"markDefs":[],"children":[{"_key":"61060e90e0ca","_type":"span","marks":["strong"],"text":"Kidney Compass: Hierarchical Composite Endpoints in Nephrology"}],"_type":"block","style":"h3","_key":"7cd6c00f17a6"},{"markDefs":[{"href":"https://www.hcplive.com/view/kidney-compass-hierarchical-composite-endpoints-nephrology-dustin-little-md-niels-jongs-phd","_key":"1a319162f909","nofollow":true,"blank":true,"_type":"link"}],"children":[{"text":"Part 1: Introductions, HCEs in Nephrology","_key":"de43cd8053f6","_type":"span","marks":["1a319162f909","strong"]}],"_type":"block","style":"h4","_key":"ff130da4ac96"},{"children":[{"_type":"span","marks":["dc340585e013","strong"],"text":"Part 2: HCEs in Nephrology Clinical Trials","_key":"999a171f7a5c"},{"_type":"span","marks":[],"text":" ","_key":"58b6a0ee3743"},{"_type":"span","marks":["strong"],"text":"(Current Segment)","_key":"0c58122931be"}],"_type":"block","style":"h4","_key":"6b1f72602925","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-understanding-hces-nephrology-clinical-trials","_key":"dc340585e013","nofollow":true}]},{"style":"h4","_key":"797a6ebe0ed1","markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-addressing-skepticism-around-hces-nephrology","_key":"f8c3c017a4fe"}],"children":[{"_type":"span","marks":["f8c3c017a4fe","strong"],"text":"Part 3: Addressing HCE Skepticism, Potential Limitations","_key":"c7c607da34d1"}],"_type":"block"},{"markDefs":[{"_key":"8f426cf6f791","nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-applying-hierarchical-composite-endpoints-kidney-disease-trials"}],"children":[{"_type":"span","marks":["8f426cf6f791","strong"],"text":"Part 4: Applying HCEs in Kidney Disease Trials","_key":"83e2513ed2c2"}],"_type":"block","style":"h4","_key":"34e99c740d50"},{"children":[{"marks":["em"],"text":"Relevant disclosures for ","_key":"e36f1e4f68b9","_type":"span"},{"_type":"span","marks":["strong","em"],"text":"Neuen","_key":"f00010ced012"},{"text":" include AstraZeneca, Bayer, Boehringer and Ingelheim, Janssen, and others. Relevant disclosures for ","_key":"bdbe7d42f584","_type":"span","marks":["em"]},{"_key":"bb6c9caeb4a8","_type":"span","marks":["strong","em"],"text":"Wadhwani"},{"_type":"span","marks":["em"],"text":" include the National Institute of Diabetes and Digestive and Kidney Diseases, GSK, Calliditas, and Travere Therapeutics. Relevant disclosures for ","_key":"585cca5f8172"},{"_key":"5bbb16a141a5","_type":"span","marks":["strong","em"],"text":"Little"},{"_key":"6ffa9657fce1","_type":"span","marks":["em"],"text":" include AstraZeneca."}],"_type":"block","style":"normal","_key":"885c0dc6fe2f","markDefs":[]}],"title":"Kidney Compass: Understanding HCEs in Nephrology Clinical Trials","documentGroup":null,"ExcludeFromPubMedXML":false,"published":"2025-02-13T01:01:12.689Z","taxonomyMapping":[{"_key":"19989efb1579","_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference"},{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference","_key":"d2c79600ef47"},{"_type":"reference","_key":"f091c977333f","_ref":"topic_nephrology"},{"_ref":"23e43f09-f248-4adb-a02b-7704fb3aa4d3","_type":"reference","_key":"7fafb28ce00d"},{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference","_key":"edb40a108a13"},{"_ref":"207059b8-dd60-459e-b64b-762f1310f280","_type":"reference","_key":"ce4be2b5ff4a"}],"url":{"current":"kidney-compass-understanding-hces-nephrology-clinical-trials","_type":"slug"},"contentCategory":{"_id":"81559818-1ad3-49ad-86c6-f9dbe8242ec6","_updatedAt":"2020-07-08T19:29:19Z","_createdAt":"2020-07-08T19:29:19Z","_rev":"Rbpfm4lNh9K9vOrCWBt9bd","_type":"contentCategory","name":"Podcasts"},"link":"/view/kidney-compass-understanding-hces-nephrology-clinical-trials","is_visible":true,"authorMapping":[{"_ref":"180837f8-dff6-4398-b243-f1b5de0f9362","_type":"reference","_key":"ea5b71b73498"},{"_ref":"0bc0864f-1d0a-44de-9fb3-be261eec4abc","_type":"reference","_key":"387ffba967e4"}],"thumbnail":{"alt":"Kidney Compass: Navigating Clinical Trials","asset":{"_ref":"image-513a7a8843e2e6442581970b54b4ddc278e6628c-300x300-png","_type":"reference"},"_type":"mainImage"},"articleType":"News","_createdAt":"2025-02-12T20:38:06Z","_id":"e3c4b9ab-6fd8-45f2-b910-420678679bf0"},{"_rev":"NT4ETOVf4DRHVmw797EchY","articleType":"News","taxonomyMapping":[{"_type":"reference","_key":"94a265743616","_ref":"00c35849-3d97-4901-be93-6e229c2a844d"},{"_type":"reference","_key":"2243f0f64b2a","_ref":"703a1bdf-1645-43ac-9e1b-55e382091532"},{"_ref":"23e43f09-f248-4adb-a02b-7704fb3aa4d3","_type":"reference","_key":"f4ba12ee76f8"},{"_ref":"topic_nephrology","_type":"reference","_key":"059f67eeb8f5"},{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference","_key":"da991557265e"},{"_ref":"207059b8-dd60-459e-b64b-762f1310f280","_type":"reference","_key":"cbeb1407c628"}],"published":"2025-02-13T01:00:55.809Z","documentGroup":null,"url":{"current":"kidney-compass-hierarchical-composite-endpoints-nephrology-dustin-little-md-niels-jongs-phd","_type":"slug"},"_type":"article","body":[{"style":"h5","_key":"4d707409c924","markDefs":[],"children":[{"_type":"span","marks":["strong","em"],"text":"Welcome to Kidney Compass: Navigating Clinical Trials!","_key":"424d114a6af8"}],"_type":"block"},{"_key":"7d239c45cc55","videoObject":{"videoDescription":"Kidney Compass: Hierarchical Composite Endpoints in Nephrology, with Dustin Little, MD, and Niels Jongs, PhD","_type":"videoDetails","videoTitle":"Kidney Compass: Hierarchical Composite Endpoints in Nephrology, with Dustin Little, MD, and Niels Jongs, PhD","thumbnail":{"_type":"image","asset":{"_ref":"image-86c94cf700fbdec61205ae4b090110efb448acff-800x451-jpg","_type":"reference"}},"videoDuration":"PT10M32S"},"_type":"video","videoID":"6368718705112","disableAutoPlayVideo":true,"source":"brightcove"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Welcome to the first installment of a 4-part series on ","_key":"ce475cf35ce4"},{"_key":"84bd92802d3c","_type":"span","marks":["em"],"text":"Kidney Compass"},{"_type":"span","marks":[],"text":" exploring the use of hierarchical composite endpoints (HCEs) in kidney disease clinical trials.","_key":"e6b5b6a4068f"}],"_type":"block","style":"normal","_key":"bf4516ac3235"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"In this installment, hosts Brendon Neuen, MBBS, PhD, and Shikha Wadhwani, MD, MS, begin by introducing their guests Dustin Little, MD, Global Clinical Lead at AstraZeneca, and Niels Jongs, PhD, a statistician at the University of Groningen.","_key":"91ddd0d79e6c"}],"_type":"block","style":"normal","_key":"1216584f23de"},{"_type":"block","style":"normal","_key":"d48cadf30b46","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The discussion starts with an overview of traditional composite endpoints commonly used in nephrology trials, such as cardiovascular death, kidney failure, and sustained eGFR decline. Little explains key limitations of these traditional endpoints, including their reliance on first-event analysis and the disproportionate influence of rapid progressors on overall trial results. He emphasizes the need for more efficient trial designs that account for the entire study population rather than just those who reach predefined endpoints.","_key":"0b48ad9ba7d7"}]},{"markDefs":[],"children":[{"_key":"1e77ab7ef410","_type":"span","marks":[],"text":"Jongs and Little both go on to explain how HCEs aim to address these shortcomings by structuring outcomes in a prioritized hierarchy, ensuring every patient contributes meaningfully to efficacy assessments. They discuss the addition of eGFR slope as a component of HCEs, allowing for a more comprehensive evaluation of treatment effects, especially in trials where only a small subset of participants progress to major clinical events."}],"_type":"block","style":"normal","_key":"52e621305a99"},{"style":"normal","_key":"222d55cce5d2","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Jongs expands on these concerns by highlighting statistical limitations, including how composite endpoints weigh events equally despite differences in clinical significance. The conversation then shifts toward the structure of HCEs, which build upon traditional endpoints by incorporating eGFR slope to ensure that all patients contribute to efficacy assessments. By structuring events hierarchically, HCEs aim to better reflect disease progression and provide a more comprehensive assessment of treatment effects.","_key":"9cb7d513ba3f"}],"_type":"block"},{"children":[{"marks":[],"text":"For ease of viewing, we've divided this episode into 4 sections and highlighted them below.","_key":"0b3af3be724f","_type":"span"}],"_type":"block","style":"normal","_key":"c50f3c90730c","markDefs":[]},{"children":[{"text":"Kidney Compass: Hierarchical Composite Endpoints in Nephrology","_key":"d769bab75769","_type":"span","marks":["strong"]}],"_type":"block","style":"h3","_key":"ba559fcc8f7b","markDefs":[]},{"markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-hierarchical-composite-endpoints-nephrology-dustin-little-md-niels-jongs-phd","_key":"ae3c30ff7c9c"}],"children":[{"_type":"span","marks":["ae3c30ff7c9c","strong"],"text":"Part 1: Introductions, HCEs in Nephrology","_key":"e6c3995c3f05"},{"_type":"span","marks":[],"text":" ","_key":"8f2d9136128d"},{"_key":"5de78bc054c0","_type":"span","marks":["strong"],"text":"(Current Segment)"}],"_type":"block","style":"h4","_key":"dcd89017bee2"},{"_key":"ad1c99cb2dbc","markDefs":[{"_key":"74630c694c1b","nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-understanding-hces-nephrology-clinical-trials"}],"children":[{"_key":"df924a344fc0","_type":"span","marks":["74630c694c1b","strong"],"text":"Part 2: HCEs in Nephrology Clinical Trials"}],"_type":"block","style":"h4"},{"children":[{"_type":"span","marks":["640da298fd54","strong"],"text":"Part 3: Addressing HCE Skepticism, Potential Limitations","_key":"1f3801bb494d"}],"_type":"block","style":"h4","_key":"115d52a22f7b","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/view/kidney-compass-addressing-skepticism-around-hces-nephrology","_key":"640da298fd54","nofollow":true}]},{"markDefs":[{"href":"https://www.hcplive.com/view/kidney-compass-applying-hierarchical-composite-endpoints-kidney-disease-trials","_key":"8f3cf8cd051e","nofollow":true,"blank":true,"_type":"link"}],"children":[{"_type":"span","marks":["8f3cf8cd051e","strong"],"text":"Part 4: Applying HCEs in Kidney Disease Trials","_key":"04c783ef4e69"}],"_type":"block","style":"h4","_key":"9d0626d65237"},{"_key":"c89d07b539e9","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Relevant disclosures for ","_key":"aa832eb02917"},{"_type":"span","marks":["strong","em"],"text":"Neuen","_key":"349690e4d7de"},{"_key":"ca6e04899f9d","_type":"span","marks":["em"],"text":" include AstraZeneca, Bayer, Boehringer and Ingelheim, Janssen, and others. Relevant disclosures for "},{"_type":"span","marks":["strong","em"],"text":"Wadhwani","_key":"e3f8c6ff3a46"},{"_type":"span","marks":["em"],"text":" include the National Institute of Diabetes and Digestive and Kidney Diseases, GSK, Calliditas, and Travere Therapeutics. Relevant disclosures for ","_key":"329384614e0b"},{"_type":"span","marks":["strong","em"],"text":"Little","_key":"36ec0f6cab7a"},{"marks":["em"],"text":" include AstraZeneca.","_key":"2ffcaa50b41a","_type":"span"}],"_type":"block","style":"normal"}],"summary":"In part 1 of 4 from this episode, the discussion focuses on traditional composite endpoints in nephrology trials and the use of HCEs.","title":"Kidney Compass: Hierarchical Composite Endpoints in Nephrology, with Dustin Little, MD, and Niels Jongs, PhD","_updatedAt":"2025-02-13T01:00:01Z","is_visible":true,"thumbnail":{"_type":"mainImage","alt":"Kidney Compass: Navigating Clinical Tr","asset":{"_ref":"image-513a7a8843e2e6442581970b54b4ddc278e6628c-300x300-png","_type":"reference"}},"ExcludeFromPubMedXML":false,"link":"/view/kidney-compass-hierarchical-composite-endpoints-nephrology-dustin-little-md-niels-jongs-phd","contentCategory":{"_type":"contentCategory","name":"Podcasts","_id":"81559818-1ad3-49ad-86c6-f9dbe8242ec6","_updatedAt":"2020-07-08T19:29:19Z","_createdAt":"2020-07-08T19:29:19Z","_rev":"Rbpfm4lNh9K9vOrCWBt9bd"},"authorMapping":[{"_key":"5dc38f16372a","_ref":"180837f8-dff6-4398-b243-f1b5de0f9362","_type":"reference"},{"_key":"20c01e24464f","_ref":"0bc0864f-1d0a-44de-9fb3-be261eec4abc","_type":"reference"}],"_createdAt":"2025-02-12T20:28:48Z","_id":"a8b9d5b5-bf1e-42f2-a5e5-ea2edb107941"},{"_createdAt":"2025-02-05T16:42:43Z","_updatedAt":"2025-02-05T20:02:15Z","authorMapping":[{"_key":"0cd44c495e8f","_ref":"author_b79347896e2132ca32cec89052a86bd3","_type":"reference"},{"_ref":"995e9e14-35ed-4ec8-b1ac-e3b5d3dc304e","_type":"reference","_key":"d06853b21934"}],"title":"Medical Ethics Unpacked: GLP-1 Allocation and Challenges of Equitable Access","url":{"current":"medical-ethics-unpacked-glp-1-allocation-and-challenges-of-equitable-access","_type":"slug"},"articleType":"News","contentCategory":{"_createdAt":"2020-07-08T19:29:19Z","_rev":"Rbpfm4lNh9K9vOrCWBt9bd","_type":"contentCategory","name":"Podcasts","_id":"81559818-1ad3-49ad-86c6-f9dbe8242ec6","_updatedAt":"2020-07-08T19:29:19Z"},"_id":"32f58eae-1465-438d-8c0b-16fcc89a7003","_rev":"5b5UBRkxYVLsiDEgmNklrS","taxonomyMapping":[{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"224a300030dc"},{"_type":"reference","_key":"2b03c17b424a","_ref":"703a1bdf-1645-43ac-9e1b-55e382091532"},{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference","_key":"b0942d666bb7"},{"_key":"5e57f6096337","_ref":"e2d7eea7-3ac1-4620-8337-a99b02663f6c","_type":"reference"},{"_ref":"b8117455-c6b6-4075-b0a4-edbc342fbc5c","_type":"reference","_key":"34c9b0b75a4f"},{"_ref":"47dbf3e7-2e95-47ec-b6e4-10355dfa8c14","_type":"reference","_key":"96d96e5b0c8e"},{"_key":"ac91744dd674","_ref":"topic_endocrinology","_type":"reference"},{"_ref":"0b42f38c-7a65-4bb4-ac2d-86500db18ab8","_type":"reference","_key":"f33879012259"},{"_type":"reference","_key":"95ff7c806f88","_ref":"topic_psychiatry"},{"_type":"reference","_key":"c8e597b66cdc","_ref":"topic_hospital-medicine"}],"link":"/view/medical-ethics-unpacked-glp-1-allocation-and-challenges-of-equitable-access","is_visible":true,"ExcludeFromPubMedXML":false,"_type":"article","thumbnail":{"_type":"mainImage","alt":"Medical Ethics Unpacked: GLP-1 Allocation","asset":{"_ref":"image-02b907f0c3709ec8d67faa46e1a623a4f66b2f1e-676x676-png","_type":"reference"}},"body":[{"videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-4b57b529a5eaa8289c2147612565ba65779519dd-2540x1428-png","_type":"reference"}},"videoDuration":"PT47M36S","videoDescription":"Medical Ethics Unpacked: Addressing GLP-1 Allocation and Challenges of Equitable Access","_type":"videoDetails","videoTitle":"Medical Ethics Unpacked: Addressing GLP-1 Allocation "},"_type":"youtube","_key":"4b322946a9ec","url":"https://youtu.be/VlrMrkznmhU"},{"_key":"35b1368266e9","content":[{"style":"normal","_key":"d03c8b41bfc9","markDefs":[],"children":[{"_type":"span","marks":[],"text":"00:00 Introduction to GLP-1 Agonists and Ethical Considerations","_key":"fb39ec0fb5d9"}],"_type":"block"},{"children":[{"_type":"span","marks":[],"text":"03:38 Current Landscape and Insurance Coverage","_key":"33db706f5f80"}],"_type":"block","style":"normal","_key":"0be063a55915","markDefs":[]},{"_key":"0e25cdd1d5da","markDefs":[],"children":[{"text":"06:04 Fair Priority Model and Ethical Principles","_key":"6a70a2bdb6be","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"style":"normal","_key":"b44588ed1f53","markDefs":[],"children":[{"_type":"span","marks":[],"text":"13:37 Application of Principles and Tiered Allocation","_key":"895e83c5151c"}],"_type":"block"},{"_key":"0cdd7e366094","markDefs":[],"children":[{"text":"34:30 Challenges and Objections to the Framework","_key":"26a02f0888b7","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"247d54a8f0da","markDefs":[],"children":[{"_type":"span","marks":[],"text":"38:41 Future Considerations and Broader Applications","_key":"88f97ab9fafa"}]}],"_type":"sidebar","caption":"Timestamps"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"11f64d5011df"}],"_type":"block","style":"normal","_key":"fdef9b6cae69"},{"_key":"be83fd1a3fb4","markDefs":[{"_type":"link","href":"https://www.hcplive.com/shows/medical-ethics-unpacked","_key":"521cb3d64954","nofollow":false,"blank":true}],"children":[{"_type":"span","marks":[],"text":"In this episode of ","_key":"37d5d3e8c62b"},{"_type":"span","marks":["521cb3d64954"],"text":"Medical Ethics Unpacked","_key":"213ed530746c"},{"_type":"span","marks":[],"text":", hosts Steve Levine, MD, a psychiatrist, and Dominic Sisti, PhD, a bioethicist, are joined by special guest Johan Dellgren, BA, a research fellow at the University of Pennsylvania’s Department of Medical Ethics and Health Policy. Together, they explore the ethical and policy challenges surrounding the allocation of GLP-1 receptor agonists, a class of medications widely recognized for their effectiveness in treating diabetes and obesity.","_key":"5e33f2bb3002"}],"_type":"block","style":"normal"},{"_key":"72fcb6ab0e50","markDefs":[],"children":[{"marks":[],"text":"The conversation addresses the growing demand for GLP-1 drugs such as Ozempic and Wegovy, which have shown profound health benefits but remain costly and in limited supply. Dellgren outlines the complexities of insurance coverage, highlighting disparities in access between private insurers, Medicare, and Medicaid. Some insurers cover these medications as preventive care due to their potential to reduce cardiovascular risks and long-term healthcare costs, but others hesitate due to their high price tags—often exceeding $1,300 per month.","_key":"731e769215e7","_type":"span"}],"_type":"block","style":"normal"},{"style":"normal","_key":"40257fc72a5d","markDefs":[{"_type":"link","href":"https://www.nejm.org/doi/abs/10.1056/NEJMp2400978","_key":"cac8af90ba39"}],"children":[{"text":"At the core of the discussion is distributive justice: how should these scarce medications be allocated fairly? Dellgren presents a framework known as the ","_key":"0e41d7f8844f","_type":"span","marks":[]},{"_key":"bf320ec2882f","_type":"span","marks":["cac8af90ba39"],"text":"Fair Priority Model"},{"_type":"span","marks":[],"text":", developed by Dr. Ezekiel Emanuel and colleagues, which balances multiple ethical principles. The model incorporates 4 key values: maximizing benefit and minimizing harm, ensuring equal moral concern for all individuals, prioritizing the most disadvantaged, and rewarding social contribution.","_key":"791588aeb3e1"}],"_type":"block"},{"style":"normal","_key":"fb41b1dffade","markDefs":[],"children":[{"text":"A key takeaway is the prioritization of GLP-1s for obesity over diabetes, an approach based on potential years of life lost (PYLL). Dellgren explains that long-term obesity significantly shortens lifespan—by as much as 10 to 15 years in some cases. Additionally, prioritizing individuals with severe obesity could help prevent the development of type 2 diabetes and other comorbidities. The model also stratifies patients by age, prioritizing younger individuals to maximize life years saved.","_key":"53b26c50af2c","_type":"span","marks":[]}],"_type":"block"},{"markDefs":[],"children":[{"text":"Sisti and Levine challenge Dellgren on objections to the PYLL metric, particularly concerns about its racial neutrality. Dellgren explains that while the model does not explicitly factor in race, it is racism-conscious, ensuring that communities disproportionately affected by obesity and diabetes—often communities of color—are fairly represented through the prioritization of those with the highest PYLL scores.","_key":"75ce1741817b","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"5e790be3e89e"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The discussion expands to the broader implications of GLP-1 access, including the current unjust distribution system, where higher-income individuals and those with comprehensive insurance disproportionately secure these medications, even in cases where clinical need is lower.","_key":"5768d100a0b7"}],"_type":"block","style":"normal","_key":"d322b3df91f1"},{"_key":"43503ed32729","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Another key ethical issue raised is patient adherence. With limited drug supply, should patients who fail to adhere to treatment lose access in favor of those more likely to benefit? Dellgren notes that some countries, such as Iceland, already incorporate adherence-based criteria into their public insurance coverage, requiring patients to meet specific weight-loss milestones to continue treatment. The conversation also touches on whether drug patents should be suspended to allow generic production and address shortages.","_key":"25762edcf847"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"9a7ed0bdf066","markDefs":[],"children":[{"_key":"4577ffd26415","_type":"span","marks":[],"text":"Throughout, Levine, Sisti, and Dellgren emphasize the ethical complexities of rationing high-impact medications and the need for policies that balance medical necessity, social equity, and cost-effectiveness."}]},{"markDefs":[{"_type":"link","href":"https://www.nejm.org/doi/abs/10.1056/NEJMp2400978","_key":"3d6269a236de","nofollow":true,"blank":true}],"children":[{"_type":"span","marks":["strong"],"text":"Dellgren and colleague’s paper on GLP-1 allocation published in the New England Journal of Medicine can be accessed ","_key":"d89acb9769b0"},{"_type":"span","marks":["strong","3d6269a236de"],"text":"here","_key":"56c1152ea25e"},{"_type":"span","marks":["strong"],"text":".","_key":"841c12e933a0"}],"_type":"block","style":"normal","_key":"720605847d2d"},{"markDefs":[],"children":[{"_key":"0ac8a9e5f0eb","_type":"span","marks":["strong"],"text":"About Hosts:"}],"_type":"block","style":"normal","_key":"486ca3f981a6"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Steve Levine, MD: Chief patient officer at Compass Pathways","_key":"4476007741a8"}],"level":1,"_type":"block","style":"normal","_key":"5c580cf2cf2b","listItem":"bullet"},{"style":"normal","_key":"e09f399e81bf","listItem":"bullet","markDefs":[],"children":[{"_key":"b6f50f654421","_type":"span","marks":[],"text":"Dominic Sisti, PhD: Associate professor in the Department of Medical Ethics \u0026 Health Policy and the director of the Scattergood Program for the Applied Ethics of Behavioral Health Care at the University of Pennsylvania"}],"level":1,"_type":"block"},{"_key":"90cd9d8fa559","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Relevant disclosures for Sisti include Lykos Therapeutics and Tactogen. Relevant disclosures for include Levine include Compass Pathways.","_key":"b85aa62996a4"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"820a14491b55","markDefs":[],"children":[{"_key":"fd62029f547c","_type":"span","marks":["strong"],"text":"Editor's Note:"}]},{"markDefs":[],"children":[{"marks":[],"text":"The views and opinions expressed by the hosts and guests are their own and do not necessarily reflect those of ","_key":"9a518244d517","_type":"span"},{"_key":"250e15c5ee74","_type":"span","marks":["em"],"text":"HCPLive"},{"_type":"span","marks":[],"text":" or ","_key":"9ebf9c3f3200"},{"text":"MJH Life Sciences","_key":"583008bbf8ad","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":". This content is intended to encourage thoughtful discussion and does not constitute medical advice or endorsement of any particular position. Listeners are encouraged to approach these subjects with care and consult appropriate resources for further information.","_key":"d5c5232803a7"}],"_type":"block","style":"normal","_key":"5f2fd4113b73"}],"summary":"Drs. Levine and Sisti discuss the ethical challenges of GLP-1 drug allocation, exploring fairness, disparities, and policy solutions for obesity and diabetes treatment.","documentGroup":null,"published":"2025-02-05T20:00:05.256Z","seoTag":["medical ethics","GLP-1 allocation","diabetes","obesity","semaglutide","Ozempic","Wegovy","ethics","GLP-1 allocation ethics"]},{"authorMapping":[{"_ref":"50390873-f609-4f23-b2f5-a613c054c1ac","_type":"reference","_key":"ff33643f4558"}],"url":{"current":"what-is-the-global-lung-function-initiative-its-purpose-lung-function-testing-","_type":"slug"},"documentGroupMapping":[{"_ref":"partners_518","_type":"reference","_key":"5dc4902ddb6b"}],"is_visible":true,"published":"2025-02-04T15:00:00.537Z","documentGroup":null,"ExcludeFromPubMedXML":false,"_id":"cc50386b-9600-4fef-a123-dec504da8b4d","taxonomyMapping":[{"_ref":"70e7f7a6-8468-4903-9f05-65ac50dccb21","_type":"reference","_key":"cf482b7e347f"},{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"8bf43b467248"},{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference","_key":"37efb74c218e"},{"_type":"reference","_key":"f19bc7f3fb4c","_ref":"84524156-7b84-4e11-841f-e7a6e0f43d74"},{"_key":"a0df83072a56","_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference"}],"_rev":"7nUk24H6N03yRGYgJw7DMg","_type":"article","display_summary":true,"_updatedAt":"2025-02-04T15:05:45Z","thumbnail":{"asset":{"_ref":"image-19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828-png","_type":"reference"},"_type":"mainImage","alt":"What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?"},"link":"/view/what-is-the-global-lung-function-initiative-its-purpose-lung-function-testing-","summary":"In this segment of January's Lungcast episode, guests discussed the Global Lung Function Initiative (GLI) network, lung function testing, and the use of race-based normal values.","articleType":"News","_createdAt":"2025-02-04T14:35:40Z","body":[{"_type":"youtube","_key":"61a48263e82d","url":"https://youtu.be/A3Js_hVylb0","videoObject":{"thumbnail":{"_type":"image","asset":{"_ref":"image-19e07f419c2a5d4218a95208dbcc5e097a1aa59c-828x828-png","_type":"reference"}},"videoDuration":"PT7M23S","videoDescription":"What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?","_type":"videoDetails","videoTitle":"What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?"}},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"The utilization of race-based normal values in medicine, particularly in regard to pulmonary function tests, is a topic that has become more prevalent in the field of pulmonology. This refers to the practice of using a patient’s self-reported race to adjust a standard ‘normal range’ for different medical tests.","_key":"0bac8e646a4a"}],"_type":"block","style":"normal","_key":"313004c508e3"},{"markDefs":[],"children":[{"marks":[],"text":"One organization, known as the Global Lung Function Initiative (GLI), is bringing a conversation about this practice to light along with respirologists, physiologists, epidemiologists, and statisticians, with the aim of changing how lung function tests are interpreted.","_key":"96b6e0252579","_type":"span"}],"_type":"block","style":"normal","_key":"8b53bd324458"},{"markDefs":[{"nofollow":true,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/race-neutral-approach-pulmonary-function-testing-meredith-mccormack-md-and-loretta-que-md","_key":"e0b7521ce877"}],"children":[{"text":"During the ","_key":"8ee02ea17f41","_type":"span","marks":[]},{"_type":"span","marks":["e0b7521ce877"],"text":"January episode","_key":"e1346a30ea84"},{"_type":"span","marks":[],"text":" of the monthly respiratory health podcast series Lungcast, a discussion on this topic was featured between host Albert Rizzo, MD, chief medical officer of the American Lung Association (ALA), and 2 new speakers: Meredith McCormack, MD, a professor of medicine at Johns Hopkins School of Medicine and Loretta G. Que, MD, a professor of medicine at Duke University.","_key":"bbd831b60c83"}],"_type":"block","style":"normal","_key":"428cf34897e0"},{"style":"normal","_key":"b07ef99802c5","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Both experts are known for their extensive work in the field of lung health. Que and McCormick were first asked about the GLI itself and its mission today.","_key":"c12fceac2969"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"“The global lung function initiative is an international collaboration of physicians, physiologists, researchers, and industry partners, and they formed a network in [around] 2008 with the purpose of trying to improve how lung function is reported and interpreted across all age groups around the world,” Que explained. “This network has become [close to] the largest resource of reference values for routine lung function testing assembled.”","_key":"f24e655a3d5b"}],"_type":"block","style":"normal","_key":"84e22bbb44f5"},{"markDefs":[],"children":[{"_key":"af1bcda1cfd8","_type":"span","marks":[],"text":"Rizzo highlighted a set of significant publications released in 2023 on the effect of race and ethnicity on pulmonary function testing interpretation. He asked McCormack and Que to speak to the efforts that went into these publications and their recommendations, as well as the ways in which they interpret the move away from race-based predictive models for pulmonary functions progressing."}],"_type":"block","style":"normal","_key":"af1edb6f40aa"},{"children":[{"_key":"4efe08ecf057","_type":"span","marks":[],"text":"“I think one thing that's really important to note is those publications were published in 2023 but [there was a lot of] work that went into and the discussions began years prior to that,” McCormack said. “One aspect that I think is really important to note is the movement that we saw in the field of medicine in general, really reconsidering and questioning our practices related to how we think about race and medical algorithms, began years before. And one point to highlight is it was really sparked, in part, by the reflections of medical students and early career trainees.”"}],"_type":"block","style":"normal","_key":"e2e1040a8ef9","markDefs":[]},{"children":[{"_type":"span","marks":[],"text":"During the course of this Lungcast segment, both speakers highlighted the controversial use of race-based normal values in lung function testing.","_key":"e1f8e34af351"}],"_type":"block","style":"normal","_key":"486e7fbe6689","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"For additional information on the GLI and on the changing conversation regarding race-based normal values in lung function testing, view the full interview segment above.","_key":"ec7259df8e7d"}],"_type":"block","style":"normal","_key":"dab23cc55e21"},{"_key":"d30830b1cc76","markDefs":[{"_type":"link","href":"https://www.hcplive.com/podcasts/lungcast","_key":"64314ce3e2db","nofollow":true,"blank":true}],"children":[{"marks":["64314ce3e2db"],"text":"Lungcast","_key":"4116eb06c14f","_type":"span"},{"text":" is a monthly respiratory health podcast series which is hosted by Albert Rizzo, MD, the chief medical officer of the American Lung Association (ALA), and produced by the ALA and ","_key":"7770b0b002a0","_type":"span","marks":[]},{"text":"HCPLive","_key":"df4adb336b76","_type":"span","marks":["em"]},{"_type":"span","marks":[],"text":".","_key":"2ebcab624587"}],"_type":"block","style":"normal"},{"markDefs":[{"blank":true,"_type":"link","href":"https://open.spotify.com/show/1F3u1hKrwxi9snSQ0q3nti","_key":"c0013208fdd9","nofollow":true}],"children":[{"_key":"2517d79ece32","_type":"span","marks":["c0013208fdd9"],"text":"Subscribe to Lungcast on Spotify here"},{"_type":"span","marks":[],"text":", or listen to the episode below.","_key":"753777fc20e0"}],"_type":"block","style":"normal","_key":"b460d3141ddb"},{"_key":"b48897b6d94e","url":"https://open.spotify.com/embed/episode/3ya9fBI5ldozhMaU0YXns4?utm_source=generator","_type":"iframe"}],"contentCategory":{"_createdAt":"2020-05-26T14:29:02Z","_rev":"ZezawLZkqZgZ50btbe1H2u","_type":"contentCategory","name":"Videos","_id":"e9156998-a932-4247-a950-6972aad95384","_updatedAt":"2020-05-26T14:29:02Z"},"title":"What is the Global Lung Function Initiative and Its Purpose for Lung Function Testing?"},{"published":"2025-02-03T10:00:00.000Z","body":[{"children":[{"_type":"span","marks":["strong"],"text":"Welcome to ","_key":"fffb5b1c3c1a"},{"_type":"span","marks":["cdb83c1b37c1","strong","em"],"text":"Skin of Color Savvy: The Art and Science of Treating Patients of Color","_key":"321f578e1b74"},{"_key":"2a6b14d8175d","_type":"span","marks":["strong","em"],"text":"!"}],"_type":"block","style":"normal","_key":"fc8e9e6b823a","markDefs":[{"_type":"link","href":"https://www.hcplive.com/podcasts/socs-podcast","_key":"cdb83c1b37c1"}]},{"style":"normal","_key":"5f1fe4e5152d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"","_key":"3ab765c8ced7"}],"_type":"block"},{"_type":"video","videoID":"6368168616112","disableAutoPlayVideo":false,"source":"brightcove","_key":"32663c8529d1","videoObject":{"videoTitle":"Skin of Color Savvy: Pigmentary Disorders in Skin of Color, with Nada Elbuluk, MD, and Michelle Rodrigues, MBBS","thumbnail":{"_type":"image","asset":{"_type":"reference","_ref":"image-93514cac36f89d84d065115c65de72f4c7b65f07-732x410-png"}},"videoDuration":"PT20M26S","videoDescription":"In this episode, Nada Elbuluk, MD, and Michelle Rodrigues, MBBS, discuss diagnosis and management of pigmentary disorders in skin of color.","_type":"videoDetails"}},{"_type":"sidebar","caption":"Helpful Links","_key":"db93ab2a1342","content":[{"_type":"block","style":"normal","_key":"685232406d08","markDefs":[{"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/","_key":"d7610f5f07b3"}],"children":[{"marks":["d7610f5f07b3","strong"],"text":"SOCS Website","_key":"d7e9d468469f","_type":"span"}]},{"_type":"block","style":"normal","_key":"a5dda8fb675f","markDefs":[{"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/who-we-are/about-socs","_key":"68db9fb51de5"}],"children":[{"_type":"span","marks":["68db9fb51de5","strong"],"text":"About SOCS","_key":"54679ade13be"}]},{"_key":"8ea09cfd2a65","markDefs":[{"href":"https://skinofcolorsociety.org/news-media/newsletter","_key":"b811477b20e3","blank":true,"_type":"link"}],"children":[{"_type":"span","marks":["b811477b20e3","strong"],"text":"SOCS Newsletter","_key":"4a57a453c2c2"}],"_type":"block","style":"normal"},{"markDefs":[{"blank":true,"_type":"link","href":"https://skinofcolorsociety.org/who-we-are/socs-foundation-members","_key":"99874f75b20b"}],"children":[{"marks":["99874f75b20b","strong"],"text":"SOCS Foundation","_key":"055ace25e763","_type":"span"}],"_type":"block","style":"normal","_key":"436a8366c795"}]},{"_type":"sidebar","caption":"Key Timestamps","_key":"be4ab775fcfd","content":[{"children":[{"_type":"span","marks":["strong"],"text":"00:00 - Start","_key":"5a0d475fa34b"}],"_type":"block","style":"normal","_key":"8bffa53c6bf9","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"02:15 - Common Pigmentary Disorders","_key":"6f1f02021754"}],"_type":"block","style":"normal","_key":"7f93a2dfeb65"},{"_key":"fad8ebd1496a","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"04:25 - Diagnostic Workup for Pigmentary Disorders","_key":"ce0cb377e7f0"}],"_type":"block","style":"normal"},{"style":"normal","_key":"20d32466ad55","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"08:35 - Labs/Blood Work for Pigmentary Disorders","_key":"f25e316385da"}],"_type":"block"},{"markDefs":[],"children":[{"_key":"475545aa771f","_type":"span","marks":["strong"],"text":"12:10 - Prevalence of Pigmentary Disorders"}],"_type":"block","style":"normal","_key":"d89d1fa5b33a"},{"children":[{"_type":"span","marks":["strong"],"text":"14:50 - Emerging Therapies for Pigmentary Disorders","_key":"d19b333e5ba9"}],"_type":"block","style":"normal","_key":"84da80848310","markDefs":[]},{"_type":"block","style":"normal","_key":"4b6b79c4455a","markDefs":[],"children":[{"_type":"span","marks":["strong"],"text":"19:45 - Conclusion","_key":"97ee4966598d"}]}]},{"_key":"763189682716","markDefs":[],"children":[{"_type":"span","marks":[],"text":"\nIn episode 2 of ","_key":"85c4fcf3f1bf"},{"_type":"span","marks":["em"],"text":"Skin of Color Savvy: The Art and Science of Treating Patients of Color","_key":"45e17046e7c2"},{"_type":"span","marks":[],"text":", host Nada Elbuluk, MD, MSc, associate professor of dermatology at the University of Southern California and president-elect of the Skin of Color Society, is joined by a leading expert in pigmentary disorders in Michelle Rodrigues, MBBS, the founder and director of the Pigment and Skin of Colour Centre at Chroma Dermatology in Australia. Together, they explore the complexities of diagnosing and managing pigmentary disorders in diverse patient populations.","_key":"f9fa968d6ad9"}],"_type":"block","style":"normal"},{"style":"normal","_key":"db8612c6aa47","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The conversation begins with an overview of common pigmentary disorders, including post-inflammatory hyperpigmentation, acquired dermal macular hyperpigmentation, nevus of Ota, melasma, and vitiligo. Rodrigues, who also serves as a clinical associate professor at the University of Melbourne, emphasizes the importance of distinguishing between hyperpigmentation, hypopigmentation, and depigmentation, noting that accurate diagnosis relies heavily on assessing lesion location, color, and patient history. Key diagnostic tools highlighted include dermoscopy, Wood’s lamp examination, and, when necessary, skin biopsy.","_key":"249c31d498a8"}],"_type":"block"},{"children":[{"_type":"span","marks":[],"text":"The experts discuss the role of laboratory workups in specific contexts, such as screening for clotting disorders before initiating oral tranexamic acid for melasma and thyroid function tests in patients with vitiligo. They underscore the systemic associations of pigmentary disorders and the need for comprehensive patient evaluations.","_key":"a19c767a0446"}],"_type":"block","style":"normal","_key":"36b3016a85d1","markDefs":[]},{"_key":"5ee04a80cc1f","markDefs":[],"children":[{"marks":[],"text":"Addressing misconceptions, Elbuluk and Rodrigues clarify that pigmentary disorders are not exclusive to skin of color populations, though their prevalence and presentation may vary. They reference global prevalence data, noting that conditions like vitiligo and melasma affect individuals across all skin types, with certain disorders more common in specific regions and demographics.","_key":"22d1bcb175ec","_type":"span"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Emerging therapies and innovations in the management of pigmentary disorders are a focal point of the latter portions of the discussion. Rodrigues highlights advances such as novel non-hydroquinone lightening agents, such as thiamidol, the evolving use of picosecond lasers for dermal hyperpigmentation, and the potential of JAK inhibitors for vitiligo. They stress the critical role of comprehensive photoprotection, including the use of broad-spectrum sunscreens with UVA1 blockers and visible light protection through tinted formulations containing iron oxide.","_key":"e7996df5a7bd"}],"_type":"block","style":"normal","_key":"e17a70d7213e"},{"style":"normal","_key":"2ff33b1301c8","markDefs":[],"children":[{"_type":"span","marks":[],"text":"The episode concludes with a call for continued education and awareness among dermatologists to ensure accurate diagnosis, effective management, and culturally competent care for patients with pigmentary disorders.","_key":"de23745e54ba"}],"_type":"block"},{"children":[{"_key":"34503677a9f2","_type":"span","marks":[],"text":""}],"_type":"block","style":"normal","_key":"084e19a5fbdd","markDefs":[]},{"_type":"block","style":"normal","_key":"6eb8cfbcf87d","markDefs":[],"children":[{"_type":"span","marks":["em"],"text":"Hosted by Skin of Color Society and produced by HCPLive, ","_key":"8b10f0cd3b29"},{"_type":"span","marks":["strong","em"],"text":"Skin of Color Savvy","_key":"5ad707acc611"},{"marks":["em"],"text":" delves into the latest research, clinical insights, and culturally competent care practices in dermatology with leading experts. Whether it’s groundbreaking research, practice-changing insights, or highlights from the SOCS community, this twice-monthly program provides dermatologists and care providers with expert perspectives on treating patients with skin of color.","_key":"ab4403499f41","_type":"span"}]},{"style":"normal","_key":"908bbc4904b3","markDefs":[],"children":[{"marks":[],"text":"","_key":"4d98d3cfe56a","_type":"span"}],"_type":"block"},{"children":[{"_type":"span","marks":["em"],"text":"Relevant disclosures for Elbuluk include Incyte. Rodrigues has no relevant disclosures to report.","_key":"c022cf665335"}],"_type":"block","style":"normal","_key":"aae7d164916a","markDefs":[]}],"contentCategory":{"_createdAt":"2020-07-08T19:29:19Z","_rev":"Rbpfm4lNh9K9vOrCWBt9bd","_type":"contentCategory","name":"Podcasts","_id":"81559818-1ad3-49ad-86c6-f9dbe8242ec6","_updatedAt":"2020-07-08T19:29:19Z"},"title":"Skin of Color Savvy: Pigmentary Disorders in Skin of Color, with Nada Elbuluk, MD, MSc, and Michelle Rodrigues, MBBS","ExcludeFromPubMedXML":false,"articleType":"News","_type":"article","_createdAt":"2025-02-02T19:49:00Z","is_visible":true,"thumbnail":{"alt":"Skin of Color Savvy: Pigmentary Disorders in Skin of Color, with Nada Elbuluk, MD, and Michelle Rodrigues, MBBS","asset":{"_ref":"image-433eea0c726eff675e9a1dd089ba0ef31db0aacd-1200x1200-png","_type":"reference"},"_type":"mainImage"},"_updatedAt":"2025-02-03T21:28:39Z","documentGroup":null,"_rev":"NM6jX99S8M6pthZactumk4","_id":"6e9c39bf-7625-4f7a-b503-8e58b0efa28e","taxonomyMapping":[{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"d481602ba84d"},{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference","_key":"76596b184646"},{"_ref":"93d97c16-5d1e-4f47-80c7-1247e47b54ba","_type":"reference","_key":"dca926f629f1"},{"_ref":"topic_dermatology","_type":"reference","_key":"e661ce03de33"},{"_ref":"d9a8cdb1-b21c-45a1-a1b4-0f2e14d4c5f9","_type":"reference","_key":"925e44237934"},{"_ref":"71feb86d-3e1f-46c8-9508-28c43eddc1bc","_type":"reference","_key":"5eb7e708e315"}],"link":"/view/skin-of-color-savvy-pigmentary-disorders-in-skin-of-color-with-nada-elbuluk-md-and-michelle-rodrigues-mbbs","url":{"current":"skin-of-color-savvy-pigmentary-disorders-in-skin-of-color-with-nada-elbuluk-md-and-michelle-rodrigues-mbbs","_type":"slug"},"summary":"In this episode, Nada Elbuluk, MD, and Michelle Rodrigues, MBBS, discuss diagnosis and management of pigmentary disorders in skin of color."}],"features":[{"_type":"feature","is_active":true,"_id":"40198ee9-cc4e-464d-89dd-6b4e405d7125","feature_img":{"_rev":"sOWhMCz0Xprw5U21EVGLJg","mimeType":"image/png","size":372076,"_id":"image-99b45b5c8555524da335c771be1d87b954404835-1200x600-png","_updatedAt":"2022-01-24T22:44:01Z","originalFilename":"LungcastFeature.png","extension":"png","metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1200,"aspectRatio":2,"height":600},"isOpaque":true,"blurHash":"MD85y%=.xuT2IUX=XWWCV?f69GIWRjoJtQ","_type":"sanity.imageMetadata","palette":{"dominant":{"population":18.37,"background":"#0c549c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.09,"background":"#253740"},"muted":{"population":1.16,"background":"#586f94","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"background":"#aad1f3","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000","population":4.83},"darkVibrant":{"population":2.03,"background":"#044f98","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"background":"#a6b5c0","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.16},"vibrant":{"background":"#0c549c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":18.37}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"uploadId":"5nOtpF8lLx7kh0QcKr7TP7o1iWgleEIW","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/99b45b5c8555524da335c771be1d87b954404835-1200x600.png","path":"images/0vv8moc6/hcplive/99b45b5c8555524da335c771be1d87b954404835-1200x600.png","assetId":"99b45b5c8555524da335c771be1d87b954404835","_createdAt":"2022-01-24T22:44:01Z","_type":"sanity.imageAsset","sha1hash":"99b45b5c8555524da335c771be1d87b954404835"},"_createdAt":"2022-01-24T22:44:29Z","thumbnail":{"_type":"image","asset":{"_type":"sanity.imageAsset","mimeType":"image/png","path":"images/0vv8moc6/hcplive/99b45b5c8555524da335c771be1d87b954404835-1200x600.png","assetId":"99b45b5c8555524da335c771be1d87b954404835","originalFilename":"LungcastFeature.png","sha1hash":"99b45b5c8555524da335c771be1d87b954404835","_id":"image-99b45b5c8555524da335c771be1d87b954404835-1200x600-png","metadata":{"palette":{"darkMuted":{"foreground":"#fff","title":"#fff","population":0.09,"background":"#253740","_type":"sanity.imagePaletteSwatch"},"muted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.16,"background":"#586f94"},"lightVibrant":{"foreground":"#000","title":"#000","population":4.83,"background":"#aad1f3","_type":"sanity.imagePaletteSwatch"},"darkVibrant":{"foreground":"#fff","title":"#fff","population":2.03,"background":"#044f98","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"title":"#fff","population":0.16,"background":"#a6b5c0","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"title":"#fff","population":18.37,"background":"#0c549c","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":18.37,"background":"#0c549c"},"_type":"sanity.imagePalette"},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"aspectRatio":2,"height":600,"_type":"sanity.imageDimensions","width":1200},"isOpaque":true,"blurHash":"MD85y%=.xuT2IUX=XWWCV?f69GIWRjoJtQ","_type":"sanity.imageMetadata"},"uploadId":"5nOtpF8lLx7kh0QcKr7TP7o1iWgleEIW","_rev":"sOWhMCz0Xprw5U21EVGLJg","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/99b45b5c8555524da335c771be1d87b954404835-1200x600.png","size":372076,"extension":"png","_createdAt":"2022-01-24T22:44:01Z","_updatedAt":"2022-01-24T22:44:01Z"}},"_rev":"TRG5qAR6yIAGryBt2O8tHa","feature_url":"/","feature_alt":"Lungcast","_updatedAt":"2022-04-12T16:01:05Z","sortOrder":8,"feature_link":"https://www.hcplive.com/podcasts/lungcast","summary":null,"title":null},{"feature_title":"Don’t Miss a Beat","_rev":"Zcw3ZAVYiYBcaECEf31f4u","_createdAt":"2023-06-06T16:55:59Z","thumbnail":{"_type":"image","asset":{"path":"images/0vv8moc6/hcplive/f42da6a69af6abf349a8739e36c3c757ce137e8a-1200x600.png","extension":"png","metadata":{"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"_type":"sanity.imageDimensions","width":1200,"aspectRatio":2,"height":600},"isOpaque":true,"blurHash":"M~L#2*~qt7IUWBj[j[a|fQj[ozofjtaeae","_type":"sanity.imageMetadata","palette":{"darkMuted":{"population":19.74,"background":"#3c3c3c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"title":"#fff","population":0.03,"background":"#ab5356","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000","population":0.07,"background":"#e8d8c8"},"darkVibrant":{"title":"#fff","population":0,"background":"#5d4227","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"background":"#bdbfc0","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":1.28},"vibrant":{"population":0,"background":"#b37f4b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":19.74,"background":"#3c3c3c"},"_type":"sanity.imagePalette"}},"uploadId":"3ccu99b7s0oKNzKceN1rfurfUfbUcw7O","_type":"sanity.imageAsset","mimeType":"image/png","originalFilename":"DontMissABeatFeature.png","sha1hash":"f42da6a69af6abf349a8739e36c3c757ce137e8a","_id":"image-f42da6a69af6abf349a8739e36c3c757ce137e8a-1200x600-png","size":172488,"assetId":"f42da6a69af6abf349a8739e36c3c757ce137e8a","_createdAt":"2023-06-06T16:55:51Z","_updatedAt":"2023-06-06T16:55:51Z","_rev":"1n8czVE5EHrVhbsiiqbasc","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/f42da6a69af6abf349a8739e36c3c757ce137e8a-1200x600.png"}},"feature_url":"/","hide_title_body":true,"feature_alt":"Don’t Miss a Beat","_updatedAt":"2023-06-06T16:55:59Z","is_active":true,"feature_link":"https://www.hcplive.com/podcasts/dont-miss-a-beat","title":"Don’t Miss a Beat","_id":"3d6751bd-ef32-4e47-9f44-865cbd036b50","feature_img":{"metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1200,"aspectRatio":2,"height":600},"isOpaque":true,"blurHash":"M~L#2*~qt7IUWBj[j[a|fQj[ozofjtaeae","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"background":"#3c3c3c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":19.74},"muted":{"population":0.03,"background":"#ab5356","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#000","population":0.07,"background":"#e8d8c8"},"darkVibrant":{"title":"#fff","population":0,"background":"#5d4227","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":1.28,"background":"#bdbfc0"},"vibrant":{"population":0,"background":"#b37f4b","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"dominant":{"population":19.74,"background":"#3c3c3c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAAKCAYAAAC0VX7mAAAACXBIWXMAAA7EAAAOxAGVKw4bAAABzUlEQVQokXWSbXPSQBSF88fUseU94S2QBL9Yi60D1vavqdUGpb9CqJUPMuO0MkCwYJWkAkkeZzekpR+6O2fuze7syb33HCUMQx6CWJ7n0Wq12Nt/happqFqebE6VELmq5dHyBRnTmSxKiNjREjH6viN0PRe71aLRbKJXqlSqBnqlcptXqgZVIzoTP1GCMOTfYsHcc5m7Lt7NDYvlkuVqSRAG8vyjbfNyb59iqUzVMDFMC9OqSRimJQnzhSLbiSSK7/uMxmO+9XoS/X6fwc8LJoNL/l45/J7+4vjDMc93dmRLhWKJsi4qrFDWdUplnXyhQCKZ4tHjJygr32cwHNI9+0qn2+W82+H7WYeL8y9M+j2cyx+8f/eWF7t1UukMOTWao0CcZ3MqyVSare2EaDmQbc6ur5nOplxNHGbOiNl4wB9nyNQZYds2zdcHsuW4qk0US+U1SpEoQYwwwA98idVqie+vmLtz2qenHB4drQUwb+do1aIZxsKIqNyzysYWYkUqe3xutzl4cygfCALDNKUgVu0ZpiVEMeWdqPI+4YM+/ESj0ZTtxhXGJHHVQihpm7UF74y4jpuEJyc2u/U6mWxOmjiCEEaTwgiIu6db2/wHnuhAIjreKGMAAAAASUVORK5CYII="},"_rev":"1n8czVE5EHrVhbsiiqbasc","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/f42da6a69af6abf349a8739e36c3c757ce137e8a-1200x600.png","size":172488,"_createdAt":"2023-06-06T16:55:51Z","_updatedAt":"2023-06-06T16:55:51Z","extension":"png","uploadId":"3ccu99b7s0oKNzKceN1rfurfUfbUcw7O","sha1hash":"f42da6a69af6abf349a8739e36c3c757ce137e8a","assetId":"f42da6a69af6abf349a8739e36c3c757ce137e8a","_type":"sanity.imageAsset","mimeType":"image/png","path":"images/0vv8moc6/hcplive/f42da6a69af6abf349a8739e36c3c757ce137e8a-1200x600.png","_id":"image-f42da6a69af6abf349a8739e36c3c757ce137e8a-1200x600-png","originalFilename":"DontMissABeatFeature.png"},"_type":"feature","summary":null},{"hide_title_body":true,"feature_url":"/","is_active":true,"feature_link":"https://www.hcplive.com/podcasts/diabetes-dialogue","_id":"826da5b6-504c-4d0b-bdb3-29c079fe798e","feature_alt":"Diabetes Dialogue","summary":null,"thumbnail":{"_type":"image","asset":{"_id":"image-beb8dd963b15661be9245a4e6abc80b22d913196-1200x600-png","extension":"png","uploadId":"yOgRXcovoV1OKyglMf3Bi6G9Rw5f9ZDR","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/beb8dd963b15661be9245a4e6abc80b22d913196-1200x600.png","_createdAt":"2023-06-06T16:55:12Z","originalFilename":"DiabetesDialogueFeature.png","_rev":"1n8czVE5EHrVhbsiiqbYi6","_type":"sanity.imageAsset","path":"images/0vv8moc6/hcplive/beb8dd963b15661be9245a4e6abc80b22d913196-1200x600.png","size":260073,"assetId":"beb8dd963b15661be9245a4e6abc80b22d913196","metadata":{"isOpaque":true,"blurHash":"MyPF}[?^IAaxx]n%jtkCfkfQ-;xvaeaeof","_type":"sanity.imageMetadata","palette":{"lightVibrant":{"title":"#fff","population":0.09,"background":"#e78888","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"foreground":"#fff","title":"#fff","population":3.9,"background":"#7d1b23","_type":"sanity.imagePaletteSwatch"},"lightMuted":{"population":0.01,"background":"#d8acc4","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"foreground":"#000","title":"#fff","population":5.84,"background":"#c48e77","_type":"sanity.imagePaletteSwatch"},"dominant":{"title":"#fff","population":5.84,"background":"#c48e77","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"_type":"sanity.imagePalette","darkMuted":{"population":4.44,"background":"#7a5b51","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"muted":{"background":"#a6755c","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.1}},"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"aspectRatio":2,"height":600,"_type":"sanity.imageDimensions","width":1200}},"mimeType":"image/png","sha1hash":"beb8dd963b15661be9245a4e6abc80b22d913196","_updatedAt":"2023-06-06T16:55:12Z"}},"feature_title":"Diabetes Dialogue","_rev":"xIRGrKPm5iTJNmzQVzWs3z","_updatedAt":"2023-06-06T16:55:24Z","feature_img":{"_updatedAt":"2023-06-06T16:55:12Z","_type":"sanity.imageAsset","sha1hash":"beb8dd963b15661be9245a4e6abc80b22d913196","path":"images/0vv8moc6/hcplive/beb8dd963b15661be9245a4e6abc80b22d913196-1200x600.png","assetId":"beb8dd963b15661be9245a4e6abc80b22d913196","originalFilename":"DiabetesDialogueFeature.png","extension":"png","metadata":{"isOpaque":true,"blurHash":"MyPF}[?^IAaxx]n%jtkCfkfQ-;xvaeaeof","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":4.44,"background":"#7a5b51","_type":"sanity.imagePaletteSwatch"},"muted":{"title":"#fff","population":0.1,"background":"#a6755c","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightVibrant":{"population":0.09,"background":"#e78888","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"darkVibrant":{"background":"#7d1b23","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.9},"lightMuted":{"population":0.01,"background":"#d8acc4","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"population":5.84,"background":"#c48e77","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"dominant":{"title":"#fff","population":5.84,"background":"#c48e77","_type":"sanity.imagePaletteSwatch","foreground":"#000"}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAAKCAYAAAC0VX7mAAAACXBIWXMAAA7EAAAOxAGVKw4bAAAB+0lEQVQokZWS628SQRTF9w8ur+DjiwItSsVoDVpjUkqAQvnAs+wulIDYVtCWpUAozwWSRg11oeAjNNCwW46ZgaIf6yS/3NxM5uTcO4fBf5wbRUG/XUPO/RqJ9XvYt+gpcYue9inrAzCKcoPpdEpRZJk+WkJ6WYZC7qYy5OtrSM0zZB2vEF3TImJSU8ImNfZWNYg/1YO57Em46H7DxdcvkDod9EURg1Yb/WYTUqUCqVpFr16n9Xu5DDG9jw9v16lI0KCiBAwrtOee6MDkPh2ieHqMinCMEsei6PWi7POh5PEgv2VHwenCmd+PkteLonsHgsuO5IYJYZNmKRg0qKhT1qwFs7O9iWjQh6NkHJmgH1mHAzmnE4LLhZNtByXv8aCw60OD51HjI0hvWhAyqqmzwEKQOGTXtGBszx7hnc0K/64bKXYPWY7FCcdBiMVxmkhAiMUg8DzqmQwG5+foVgo42HpBhYhgkNTHKwgZVXPBVCyEWDSA98kESoUCxEYdrUaD0hFFtJtNdMg+u11Mrq4gtao4tL9cjhoyzncZNqrBmXVgfv/6ieFggB/DIUajEcaTyZzx+C+TySIFU/RaVXx0bCxH/neHPPmUOwVwNlvkUKY5/OyygTXr6N4IkVUNdUcyycxmM9yFW8HLdg15zxskrfeXwSahJn36+UP8AeQ9jtSOQafLAAAAAElFTkSuQmCC","dimensions":{"_type":"sanity.imageDimensions","width":1200,"aspectRatio":2,"height":600}},"url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/beb8dd963b15661be9245a4e6abc80b22d913196-1200x600.png","_createdAt":"2023-06-06T16:55:12Z","uploadId":"yOgRXcovoV1OKyglMf3Bi6G9Rw5f9ZDR","_rev":"1n8czVE5EHrVhbsiiqbYi6","mimeType":"image/png","size":260073,"_id":"image-beb8dd963b15661be9245a4e6abc80b22d913196-1200x600-png"},"title":"Diabetes Dialogue","_createdAt":"2023-06-06T16:55:24Z","_type":"feature"},{"hide_title_body":true,"_createdAt":"2023-06-06T16:54:00Z","feature_url":"/","feature_img":{"_rev":"88I1wXO1tUGdJDzEnaa9yy","size":376230,"_id":"image-c24dea9a5ca5fb10b4485d0edcac7fe471c4c949-1200x600-png","_updatedAt":"2023-06-06T16:53:01Z","uploadId":"SLTgJzII6DK3Q3zHzTJNt6XcVHgdpbrE","sha1hash":"c24dea9a5ca5fb10b4485d0edcac7fe471c4c949","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/c24dea9a5ca5fb10b4485d0edcac7fe471c4c949-1200x600.png","assetId":"c24dea9a5ca5fb10b4485d0edcac7fe471c4c949","_createdAt":"2023-06-06T16:53:01Z","metadata":{"dimensions":{"_type":"sanity.imageDimensions","width":1200,"aspectRatio":2,"height":600},"isOpaque":true,"blurHash":"M]RK2fhekCv#xuxuozbHWBbHofofj[aeWB","_type":"sanity.imageMetadata","palette":{"muted":{"title":"#fff","population":0.68,"background":"#a3a7a5","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"lightVibrant":{"population":0.02,"background":"#f49c84","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"darkVibrant":{"population":1.95,"background":"#bd2728","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightMuted":{"population":0.56,"background":"#d7bec1","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff"},"vibrant":{"population":12.95,"background":"#ec2424","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"dominant":{"title":"#fff","population":12.95,"background":"#ec2424","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"_type":"sanity.imagePalette","darkMuted":{"background":"#222222","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":4.58}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"_type":"sanity.imageAsset","originalFilename":"NewInsightFeature.png","extension":"png","mimeType":"image/png","path":"images/0vv8moc6/hcplive/c24dea9a5ca5fb10b4485d0edcac7fe471c4c949-1200x600.png"},"_id":"8cafcf25-a7ef-438c-b9f5-6d567fb8d755","_updatedAt":"2023-06-06T16:54:00Z","is_active":true,"_rev":"1n8czVE5EHrVhbsiiqbUP0","summary":null,"thumbnail":{"_type":"image","asset":{"metadata":{"hasAlpha":true,"lqip":"data:image/png;base64,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","dimensions":{"height":600,"_type":"sanity.imageDimensions","width":1200,"aspectRatio":2},"isOpaque":true,"blurHash":"M]RK2fhekCv#xuxuozbHWBbHofofj[aeWB","_type":"sanity.imageMetadata","palette":{"lightMuted":{"foreground":"#000","title":"#fff","population":0.56,"background":"#d7bec1","_type":"sanity.imagePaletteSwatch"},"vibrant":{"background":"#ec2424","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":12.95},"dominant":{"background":"#ec2424","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":12.95},"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":4.58,"background":"#222222"},"muted":{"background":"#a3a7a5","_type":"sanity.imagePaletteSwatch","foreground":"#000","title":"#fff","population":0.68},"lightVibrant":{"title":"#fff","population":0.02,"background":"#f49c84","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"darkVibrant":{"background":"#bd2728","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.95}}},"uploadId":"SLTgJzII6DK3Q3zHzTJNt6XcVHgdpbrE","originalFilename":"NewInsightFeature.png","extension":"png","_createdAt":"2023-06-06T16:53:01Z","_updatedAt":"2023-06-06T16:53:01Z","_rev":"88I1wXO1tUGdJDzEnaa9yy","_type":"sanity.imageAsset","mimeType":"image/png","sha1hash":"c24dea9a5ca5fb10b4485d0edcac7fe471c4c949","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/c24dea9a5ca5fb10b4485d0edcac7fe471c4c949-1200x600.png","size":376230,"assetId":"c24dea9a5ca5fb10b4485d0edcac7fe471c4c949","_id":"image-c24dea9a5ca5fb10b4485d0edcac7fe471c4c949-1200x600-png","path":"images/0vv8moc6/hcplive/c24dea9a5ca5fb10b4485d0edcac7fe471c4c949-1200x600.png"}},"_type":"feature","feature_link":"https://www.hcplive.com/podcasts/new-insight","feature_alt":"New Insight with Dr. Veeral Sheth","title":"New Insight with Dr. Veeral Sheth","feature_title":"New Insight with Dr. Veeral Sheth"},{"_rev":"1n8czVE5EHrVhbsiiqbhTy","feature_link":"https://www.hcplive.com/shows/crisis-point","thumbnail":{"_type":"image","asset":{"metadata":{"dimensions":{"width":1200,"aspectRatio":2,"height":600,"_type":"sanity.imageDimensions"},"isOpaque":true,"blurHash":"MhGRuN~qx[M{M{ofkCofoLjY8_DjRjozkB","_type":"sanity.imageMetadata","palette":{"muted":{"background":"#895b60","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":8.08},"lightVibrant":{"background":"#d17669","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":0.04},"darkVibrant":{"title":"#fff","population":8.28,"background":"#44080a","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"title":"#fff","population":0.85,"background":"#d6b9bd","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"background":"#b5545a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":1.14},"dominant":{"foreground":"#fff","title":"#fff","population":8.28,"background":"#44080a","_type":"sanity.imagePaletteSwatch"},"_type":"sanity.imagePalette","darkMuted":{"foreground":"#fff","title":"#fff","population":3.46,"background":"#62353b","_type":"sanity.imagePaletteSwatch"}},"hasAlpha":true,"lqip":"data:image/png;base64,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"},"uploadId":"1Vf5DW74KKNIK6QlfPsLdxLfSUfTFH4w","_rev":"88I1wXO1tUGdJDzEnabB5d","mimeType":"image/png","assetId":"f9474953f8fe890c8941e21a9637a272bdff3881","extension":"png","_type":"sanity.imageAsset","sha1hash":"f9474953f8fe890c8941e21a9637a272bdff3881","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/f9474953f8fe890c8941e21a9637a272bdff3881-1200x600.png","size":452062,"originalFilename":"CrisisPointFeature.png","_id":"image-f9474953f8fe890c8941e21a9637a272bdff3881-1200x600-png","_updatedAt":"2023-06-06T16:57:12Z","path":"images/0vv8moc6/hcplive/f9474953f8fe890c8941e21a9637a272bdff3881-1200x600.png","_createdAt":"2023-06-06T16:57:12Z"}},"hide_title_body":true,"feature_url":"/","title":"Crisis Point","is_active":true,"_type":"feature","feature_title":"Crisis Point","feature_img":{"metadata":{"dimensions":{"width":1200,"aspectRatio":2,"height":600,"_type":"sanity.imageDimensions"},"isOpaque":true,"blurHash":"MhGRuN~qx[M{M{ofkCofoLjY8_DjRjozkB","_type":"sanity.imageMetadata","palette":{"_type":"sanity.imagePalette","darkMuted":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":3.46,"background":"#62353b"},"muted":{"population":8.08,"background":"#895b60","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"lightVibrant":{"title":"#fff","population":0.04,"background":"#d17669","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"darkVibrant":{"title":"#fff","population":8.28,"background":"#44080a","_type":"sanity.imagePaletteSwatch","foreground":"#fff"},"lightMuted":{"title":"#fff","population":0.85,"background":"#d6b9bd","_type":"sanity.imagePaletteSwatch","foreground":"#000"},"vibrant":{"population":1.14,"background":"#b5545a","_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff"},"dominant":{"_type":"sanity.imagePaletteSwatch","foreground":"#fff","title":"#fff","population":8.28,"background":"#44080a"}},"hasAlpha":true,"lqip":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABQAAAAKCAYAAAC0VX7mAAAACXBIWXMAAA7EAAAOxAGVKw4bAAACl0lEQVQokVWSW0iTcRjG/wpGF91FVJSn1B2c+zbd5r5vtdrcTPetqVlmgWVCJ0yNorSoi24jMqjboEiclrYwtbMHgtnBiMq0UESoqHURlp0uf/F9o4suHv7P1fN/3vf3iqAQBEQKJSIFn0jBKwQeIZBTU3EuWoxzyVLWLU3HuyIHX6aJkMlGhdVBheRkk6WQcL6dSEGR7svyLIhmRaFJljnolmmUFQ4oCvs9HhrcbiIGM95lqylbnk0kw4xqkPSg6iKZaodMlc1Fpc1Flb1Y91qoGOvrYzQaZbizk0exGPH+fuIDAzzs6eHC8ZPUO9dSn1tAk83NriIlGVYks8WR9JsL3bq0UK2p+LOwwNe5ORIzM3z7kuD3wnd+zc/z9eNHnt97QPveRlo9Pk6Xhmn0baRScv03ZjjfritkkpIj//75gw+zs0y/fsXMmwlm304xOzXJ+6lJZp6N03GmnSNqNW0VtewJhCkzWAlmGynNMRNcYyKYrcmIPyMX78osRCKRYHRkmN7r14h2dNB59Sq3YjFexuO8e/KUy2fOsy+0lQORHdT5VcqNEiGjFdVs01uFjBLlBiuBbCPrVmQiPn/6xOOxMW4PDnIzFiN24wYjQ0NMT0zwYmiEs81H2e1VqfNXUOlcj5pv18HoIOzFuo9YHfoH/ow8RLyvj+HeXu53d3M3GuVhVxfjAwNMjoxy59IVTtXspEEuZbu8EbXATdhSqBPV9A+IRlrbaSDLgGhRFFo8Hpo9a3W1bfBxsWYb3UeOcelQKyc2baFBDlBbHES1uPSGWkCl5Ey+Npd+l6rJhi89F6EddokQ+IXAJwRqWhrNmVmcK1Vpr6njsL+czRYHgVwJb7qBkiwjYXOSrGqSdGk71KAoy1bxF1ttodWcSqdsAAAAAElFTkSuQmCC"},"uploadId":"1Vf5DW74KKNIK6QlfPsLdxLfSUfTFH4w","_type":"sanity.imageAsset","mimeType":"image/png","sha1hash":"f9474953f8fe890c8941e21a9637a272bdff3881","assetId":"f9474953f8fe890c8941e21a9637a272bdff3881","extension":"png","size":452062,"_createdAt":"2023-06-06T16:57:12Z","url":"https://cdn.sanity.io/images/0vv8moc6/hcplive/f9474953f8fe890c8941e21a9637a272bdff3881-1200x600.png","path":"images/0vv8moc6/hcplive/f9474953f8fe890c8941e21a9637a272bdff3881-1200x600.png","originalFilename":"CrisisPointFeature.png","_rev":"88I1wXO1tUGdJDzEnabB5d","_updatedAt":"2023-06-06T16:57:12Z","_id":"image-f9474953f8fe890c8941e21a9637a272bdff3881-1200x600-png"},"feature_alt":"Crisis Point","_updatedAt":"2023-06-06T16:57:20Z","_id":"e1705012-b5ae-4103-872b-d9c2e149cf28","summary":null,"_createdAt":"2023-06-06T16:57:20Z"}],"conferences":[{"gptTakeaways":"• Tapinarof cream 1% showed significant efficacy and tolerability in treating atopic dermatitis in patients aged two and older.\n\n• Phase 3 trials demonstrated substantial EASI score improvements across body regions, including sensitive areas like the face and neck.\n\n• The FDA cleared Alphyn Biologics' Zabalafin Hydrogel, a botanical drug targeting multiple aspects of atopic dermatitis, for investigational use.","title":"Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis","_id":"c9385425-36e7-46fa-835d-a7edf6ef58ff","summary":"In new data to be presented at AAAAI, the therapy was well-tolerated in people as young as 2 years old.","documentGroup":{"docGroupArchive":false,"identifier":{"current":"american-academy-of-allergy-asthma-and-immunology-dermatology","_type":"slug"},"parent":{"_ref":"6f7fd681-6891-42d5-a963-e7cfdaba9d24","_type":"reference"},"_createdAt":"2025-01-10T16:46:52Z","_type":"documentGroup","name":"American Academy of Allergy, Asthma \u0026 Immunology - Dermatology","_id":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_rev":"lMqTJ7iiwxFTeHbLVRZGYG","_updatedAt":"2025-01-10T16:47:09Z"},"_createdAt":"2025-02-20T23:57:37Z","authorMapping":[{"_ref":"d4c32d40-a161-4f01-8151-702eff7a6e75","_type":"reference","_key":"4f20a1abb85c"}],"gptSummary":"Tapinarof cream 1% demonstrated significant efficacy and tolerability in treating atopic dermatitis (AD) in patients as young as two years old, according to phase 3 trials ADORING 1 and 2. The trials showed substantial improvements in Eczema Area and Severity Index (EASI) scores across various body regions, including sensitive areas like the face and neck. Additionally, the FDA cleared Alphyn Biologics' investigational new drug application for Zabalafin Hydrogel, a botanical drug targeting multiple aspects of AD, including pruritus, bacterial components, and immuno-inflammatory responses, offering a comprehensive treatment option.","_rev":"jxkloFTwbsbZ4yXrpVQfqT","articleType":"News","_updatedAt":"2025-02-20T23:57:48Z","is_visible":true,"contentCategory":{"_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory","name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91","_updatedAt":"2023-01-17T17:54:09Z"},"drugMentions":"{\"drug_mentions\": [\"Tapinarof\", \"VTAMA®\", \"Zabalafin Hydrogel\"]}","authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"}],"thumbnail":{"caption":"Tapinarof Demonstrates Consistent Efficacy Across Body Regions in People With Atopic Dermatitis\n","asset":{"_ref":"image-f5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366-jpg","_type":"reference"},"_type":"mainImage","alt":"Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati"},"_type":"article","published":"2025-02-21T00:00:46.772Z","url":"tapinarof-consistent-efficacy-across-body-regions-ad","audioUrl":"https://s3.us-east-1.amazonaws.com/ai-generated-audios/www.hcplive.com/c9385425-36e7-46fa-835d-a7edf6ef58ff_1740095862632.8a3f38ca-039f-4464-9229-da41c1ad1f1c.mp3","taxonomyMapping":[{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"f352a3bdd046"},{"_ref":"topic_atopic-dermatitis","_type":"reference","_key":"fe1c09e2fd58"},{"_ref":"topic_dermatology","_type":"reference","_key":"080e1dc2a3f9"},{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference","_key":"0a52aa9733f3"},{"_ref":"6e1a5e9c-c5e9-4d19-b803-e00d93da7863","_type":"reference","_key":"a382e7ca5201"}],"documentGroupMapping":[{"_ref":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_type":"reference","_key":"4e8e7e858359"}],"body":[{"_key":"6b9fe40c7498","alignment":"right","widthP":33,"asset":{"_ref":"image-f5a6f11e3fe90d7ce6d108e39baf6ccfda31938a-343x366-jpg","_type":"reference"},"disableLightBox":true,"alt":"Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati","disableTextWrap":false,"_type":"figure","imgcaption":[{"children":[{"_type":"span","marks":[],"text":"Justin Greiwe, MD","_key":"28d183418d4e"}],"_type":"block","style":"normal","_key":"94c99bf868c1","markDefs":[]},{"_type":"block","style":"normal","_key":"da12ed187e90","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Credit: University of Cincinnati","_key":"fc07c98e77f5"}]}]},{"_type":"block","style":"normal","_key":"4df88b90f9b3","markDefs":[],"children":[{"text":"Tapinarof was well-tolerated and demonstrated consistent efficacy across body regions in people as young as 2 years old.","_key":"61132225f0e7","_type":"span","marks":[]},{"marks":["sup"],"text":"1","_key":"0b42808e3d50","_type":"span"}]},{"children":[{"_type":"span","marks":[],"text":"These findings were presented at the 2025 American Academy of Allergy, Asthma, and Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress, February 28-March 3, in San Diego, California, by Justin Greiwe, MD, Bernstein Allergy Group, and Clinical Assistant Professor of Medicine, Division of Immunology, Allergy, and Rheumatology, University of Cincinnati.","_key":"4ab0cffa398c"}],"_type":"block","style":"normal","_key":"f0cda9ff44d1","markDefs":[]},{"children":[{"marks":[],"text":"“In the ADORING 1 and 2 phase 3 trials, tapinarof cream 1% (VTAMA®, Dermavant Sciences, Inc.) once daily (QD) demonstrated significant efficacy and was well tolerated in patients with atopic dermatitis (AD) down to age 2 years. Efficacy and tolerability of topicals may vary by body region, particularly sensitive areas including the face/neck. We present Eczema Area and Severity Index (EASI) scores by body region,” Greiwe and colleagues wrote.","_key":"130d2caf6afb","_type":"span"},{"marks":["sup"],"text":"1","_key":"7c530d955391","_type":"span"}],"_type":"block","style":"normal","_key":"fa5fe8b6ab95","markDefs":[]},{"style":"normal","_key":"400c959a8611","markDefs":[],"children":[{"_key":"ae2bc78c2e83","_type":"span","marks":[],"text":"The trials had a total of 813 participants who were randomized to tapinarof or vehicle QD for 8 weeks. Participants had moderate-to-severe AD with mean baseline EASI scores of 12.2–13.5 (standard deviation, 4.7–5.6). In ADORING 1, 55.8% of the tapinarof group and 22.9% of the placebo group achieved at least a 75% improvement in EASI at week 8 ("},{"_type":"span","marks":["em"],"text":"P","_key":"558da9d0067d"},{"_type":"span","marks":[],"text":" \u003c.0001). In ADORING 2, 59.1% of the tapinarof group and 21.2% group achieved at least a 75% improvement in EASI at week 8 (","_key":"3f501c089c3a"},{"_type":"span","marks":["em"],"text":"P","_key":"b96a6de680b8"},{"_type":"span","marks":[],"text":" \u003c.0001).","_key":"d275d2b85362"},{"_type":"span","marks":["sup"],"text":"1","_key":"e5539bc9e07b"}],"_type":"block"},{"_key":"604464cbae78","markDefs":[],"children":[{"_type":"span","marks":[],"text":"In ADORING 1, least squares (LS) mean overall EASI score improvements were –8.4 vs –4.1 (","_key":"cc150aeb2fbd"},{"_type":"span","marks":["em"],"text":"P ","_key":"d563cbee6e5d"},{"_type":"span","marks":[],"text":"\u003c.0001) at week 8 and in ADORING 2, LS mean overall EASI score improvements were –10.1 vs –5.2 (","_key":"3e0ad4264d54"},{"_type":"span","marks":["em"],"text":"P ","_key":"b5206212793a"},{"_type":"span","marks":[],"text":"\u003c.0001). By body region, LS mean changes in EASI scores by body region at Week 8 were: head/neck –8.7 vs –4.4 (ADORING 1) and –8.8 vs –4.7 (ADORING 2); trunk –5.9 vs –2.6 (ADORING 1) and –7.2 vs –3.8 (ADORING 2); upper extremities –12.0 vs –5.2 (ADORING 1) and –15.0 vs –6.6 (ADORING 2); and lower extremities –8.6 vs –4.4 (ADORING 1) and –9.9 vs –5.5 (ADORING 2; all ","_key":"9d2d82f3f950"},{"_type":"span","marks":["em"],"text":"P ","_key":"549f045874f9"},{"_key":"7d463b5fc563","_type":"span","marks":[],"text":"\u003c.0001). Investigators found that tapinarof was well tolerated across sensitive areas, including the face/neck."},{"_type":"span","marks":["sup"],"text":"1","_key":"010f500fe333"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"marks":[],"text":"In other AD news, the FDA yesterday cleared Alphyn Biologics’ investigational new drug (IND) application for Zabalafin Hydrogel for treating mild-to-moderate AD. The hydrogel is a first-in-class botanical drug and contains multiple bioactive compounds that work through diverse mechanisms of action. It is designed to address an array of aspects of atopic dermatitis simultaneously, reducing the characteristic pruritus associated with the condition, targeting the bacterial component of atopic dermatitis, and modulating the underlying immuno-inflammatory response.","_key":"fc4d58a7bccd","_type":"span"}],"_type":"block","style":"normal","_key":"c865f3e66fc2"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"“We believe it will be the compelling therapeutic choice to treat [atopic dermatitis], offering excellent patient tolerability for worry free, long-term and continuous use, and comprehensive treatment for itch, inflammation, and managing the bacterial microbiome imbalance on the skin that exacerbates the disease and its flare-ups,” Koller said in his statement,” Neal Koller, CEO at Alphyn, said in a statement.","_key":"77288eef5faa"},{"_type":"span","marks":["sup"],"text":"2","_key":"0ab8039c5dc8"}],"_type":"block","style":"normal","_key":"b3ccd1d4bc56"},{"style":"h6","_key":"ad7794f23572","markDefs":[],"children":[{"_type":"span","marks":[],"text":"REFERENCES","_key":"5d7f6b09e06f"}],"_type":"block"},{"_type":"block","style":"h6","_key":"e1b1a472cfe2","listItem":"number","markDefs":[],"children":[{"_key":"0d316edf8958","_type":"span","marks":[],"text":"Greiwe J, Tallman A, Sublett JW, et al. Tapinarof Cream 1% Once Daily: Consistent Efficacy Across All Body Regions, Including Head And Neck, In Adults And Children Down To 2 Years Of Age With Atopic Dermatitis. Presented at: 2025 AAAAI/WAO Joint Congress, February 28-March 3. Abstract 595"}],"level":1},{"style":"h6","_key":"724993540b7b","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":[],"text":"2. Alphyn Secures FDA Clearance of Investigational New Drug Application for Atopic Dermatitis Treatment. Alphyn Biologics, Inc. February 19, 2025. https://www.prnewswire.com/news-releases/alphyn-secures-fda-clearance-of-investigational-new-drug-application-for-atopic-dermatitis-treatment-302379675.html.","_key":"ffbf699ba3d5"}],"level":1,"_type":"block"}],"ExcludeFromPubMedXML":false},{"contentCategory":{"name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91","_updatedAt":"2023-01-17T17:54:09Z","_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory"},"ExcludeFromPubMedXML":false,"authorMapping":[{"_ref":"d4c32d40-a161-4f01-8151-702eff7a6e75","_type":"reference","_key":"74e4cb202c5c"}],"documentGroupMapping":[{"_ref":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_type":"reference","_key":"0cb0c0fe6ccc"}],"published":"2025-02-20T18:00:21.129Z","_updatedAt":"2025-02-20T17:52:09Z","_type":"article","authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"}],"summary":"By week 52, remibrutinib and placebo-to-remibrutinib groups had similar levels of urticaria control.","articleType":"News","title":"Add-on Remibrutinib Quickly Improves Urticaria Control in CSU","drugMentions":"{\"drug_mentions\": [\"remibrutinib\", \"barzolvolimab\"]}","_rev":"jxkloFTwbsbZ4yXrpTj5jd","url":"add-on-remibrutinib-quickly-improves-urticaria-control-csu","_createdAt":"2025-02-20T17:51:53Z","thumbnail":{"_type":"mainImage","alt":"Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany","caption":"Add-on Remibrutinib Quickly Improves Urticaria Control in CSU","asset":{"_ref":"image-3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450-tif","_type":"reference"}},"taxonomyMapping":[{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"0ecfc92432a2"},{"_ref":"topic_chronic-idiopathic-urticaria","_type":"reference","_key":"8b6a171287cd"},{"_ref":"topic_dermatology","_type":"reference","_key":"65388abd4439"},{"_key":"762f3b53f328","_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference"},{"_type":"reference","_key":"313c6ba2484b","_ref":"6e1a5e9c-c5e9-4d19-b803-e00d93da7863"}],"body":[{"disableLightBox":true,"alt":"Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany","imgcaption":[{"markDefs":[],"children":[{"_key":"5c4f00d00637","_type":"span","marks":[],"text":"Martin Metz, MD"}],"_type":"block","style":"normal","_key":"d29cc8f19aa5"},{"_type":"block","style":"normal","_key":"8bf7541fa40c","markDefs":[],"children":[{"_key":"8b2d5b2a160e","_type":"span","marks":[],"text":"Credit: Charite-Universitatsmedizin Berlin, Germany"}]}],"alignment":"right","asset":{"_ref":"image-3d9182a2548b42fcfbc4df66150ef051a4f6812e-450x450-tif","_type":"reference"},"widthP":33,"disableTextWrap":false,"_type":"figure","_key":"8bf37358548f"},{"_type":"block","style":"normal","_key":"134d0d83b2d8","markDefs":[{"_key":"74a7896e1e8e","nofollow":false,"blank":true,"_type":"link","href":"https://www.hcplive.com/view/barzolvolimab-improves-urticaria-control-quality-of-life"}],"children":[{"_type":"span","marks":[],"text":"Add-on remibrutinib quickly improved urticaria control and demonstrated superiority over placebo in patients with ","_key":"a0c4f2b69195"},{"_type":"span","marks":["74a7896e1e8e"],"text":"chronic spontaneous urticaria (CSU)","_key":"25ecb9e18fba"},{"text":", in new findings from the REMIX-1/-2 phase 3 trials.","_key":"82a48ac5a521","_type":"span","marks":[]}]},{"_key":"56e5a092722a","markDefs":[],"children":[{"_type":"span","marks":[],"text":"These data will be presented at the 2025 American Academy of Allergy, Asthma, and Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress, February 28-March 3, in San Diego, California, by Martin Metz, MD, Deputy Director, Head of Translational Research and Clinical Studies, Institute of Allergology, Charite-Universitatsmedizin Berlin, Germany.","_key":"7e6a41f69a96"}],"_type":"block","style":"normal"},{"children":[{"marks":[],"text":"“In REMIX-1/-2, add-on remibrutinib improved urticaria control as early as week 2, with improvements sustained through week 52, as measured by UCT7, a reliable, practical measurement of urticaria control,” Metz and colleagues wrote.","_key":"ee526fff132b","_type":"span"},{"_type":"span","marks":["sup"],"text":"1","_key":"ccd84d0fc738"}],"_type":"block","style":"normal","_key":"78648b0f06dd","markDefs":[]},{"_type":"block","style":"normal","_key":"ded139c0c6a3","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Remibrutinib is a novel, highly selective, oral Bruton tyrosine kinase (BTK) inhibitor evaluated for efficacy and safety in the identical REMIX-1/-2 multicenter, randomized, double-blind, placebo-controlled phase 3 trials. The trials enrolled participants with symptomatic CSU despite second-generation H1-antihistamines to be randomized 2:1 to add-on remibrutinib 25 mg twice daily (bid), or placebo. Starting at week 24, all patients received add-on open label remibrutinib 25 mg bid until week 52. Investigators assessed urticaria control using the weekly urticaria control test (UCT7) at baseline and weeks 2, 4, 12, 24, 52.","_key":"1a4d46211740"},{"_type":"span","marks":["sup"],"text":"1","_key":"9e12c18663b8"}]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Data reported are from 912 patients in the full analysis set, 606 receiving remibrutinib and 306 receiving placebo. The remibrutinib groups demonstrated fast improvements in mean change from baseline in UCT7 versus placebo at week 2 (REMIX-1: 5.74 versus 1.95; REMIX-2: 5.57 versus 2.27) and week 24 (REMIX-1: 7.17 versus 4.60; REMIX-2: 6.93 versus 4.47), which was sustained through week 52. The remibrutinib groups also had a higher proportion of patients with well controlled urticaria (UCT7 ≥12) at week 24 compared with the placebo groups (REMIX-1: 63.1% versus 41.6%; REMIX-2: 64.8% versus 40.2%), with similar proportions observed at week 52. Furthermore, patients transitioning from placebo to remibrutinib at week 24 experienced similar improvements through week 52.","_key":"7263aa84f7a1"},{"_type":"span","marks":["sup"],"text":"1","_key":"d1528bba9380"}],"_type":"block","style":"normal","_key":"d2e7780cf5bc"},{"markDefs":[],"children":[{"text":"Metz is also presenting other research in the CSU field at AAAAI on barzolvolimab from a phase 2 study demonstrating that the treatment yielded marked and sustained improvements in urticaria control and quality of life in 208 patients whose CSU was refractory to antihistamines.","_key":"f687050f62b3","_type":"span","marks":[]}],"_type":"block","style":"normal","_key":"0fbb9c0eb373"},{"_key":"9a79d9f4bfb8","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Participants in the 150mg Q4W groups had mean baseline UCT scores of 3.7 (standard deviation [SD], 2.5) and participants in the Q8W groups had mean baseline UCT scores of 3.0 (SD, 2.6), indicating poorly treated urticaria in both dosage groups. The investigators found that barzolvolimab improved UCT with a mean change from baseline at 52 weeks of 10.5 (SD, 3.9) in the Q4W groups and 9.4 (SD, 5.0) in the Q8W groups.","_key":"d3690ef74658"},{"_type":"span","marks":["sup"],"text":"2","_key":"152a9c9c840b"}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Participants in the 150mg Q4W groups had mean baseline DLQI scores of 15.7 (SD, 7.6) and participants in the 300 mg Q8W groups had mean baseline DLQI scores of 17.4 (SD, 7.5), indicating a very large impact of disease on QoL. The investigators found that barzolvolimab improved DLQI with a mean change from baseline at 52 weeks of -14.2 (SD, 7.3) in the 150mg Q4W groups and -15.0 (SD, 8.5) participants in the 300 mg Q8W groups.","_key":"20177e992afc"},{"_type":"span","marks":["sup"],"text":"2","_key":"3bb2f44bfc18"}],"_type":"block","style":"normal","_key":"62ae32493e44"},{"children":[{"_key":"6463359dddb6","_type":"span","marks":[],"text":"REFERENCES"}],"_type":"block","style":"h6","_key":"06b627e6328a","markDefs":[]},{"markDefs":[],"children":[{"text":"Metz M, Bin Y, Boren E, et al. The Impact of Remibrutinib on Urticaria Control in Patients with Chronic Spontaneous Urticaria: Long-term Results from the REMIX-1/-2 Phase 3 Trials. Presented at: 2025 AAAAI/WAO Joint Congress, February 28-March 3. Abstract 551","_key":"924a5e5b4a34","_type":"span","marks":[]}],"level":1,"_type":"block","style":"h6","_key":"0a3441567609","listItem":"number"},{"_key":"b7d4bb37aa17","listItem":"number","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Maurer M, Metz M, Kobielusz-Gembala I, et al. Barzolvolimab Improves Urticaria Control and Quality of Life in Patients with Chronic Spontaneous Urticaria: 52-Week Data. Presented at: 2025 AAAAI/WAO Joint Congress, February 28-March 3. Abstract L11.","_key":"0fc0f6aecdca"}],"level":1,"_type":"block","style":"h6"}],"_id":"9c1a57f0-3513-4098-8fb7-1f93f363b4f9","documentGroup":{"docGroupArchive":false,"identifier":{"current":"american-academy-of-allergy-asthma-and-immunology-dermatology","_type":"slug"},"parent":{"_ref":"6f7fd681-6891-42d5-a963-e7cfdaba9d24","_type":"reference"},"_createdAt":"2025-01-10T16:46:52Z","_type":"documentGroup","name":"American Academy of Allergy, Asthma \u0026 Immunology - Dermatology","_id":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_rev":"lMqTJ7iiwxFTeHbLVRZGYG","_updatedAt":"2025-01-10T16:47:09Z"},"is_visible":true,"audioUrl":"https://s3.us-east-1.amazonaws.com/ai-generated-audios/www.hcplive.com/9c1a57f0-3513-4098-8fb7-1f93f363b4f9_1740073918094.df2cc149-2831-4fd2-a5d1-25420aec8a81.mp3"},{"audioUrl":"https://s3.us-east-1.amazonaws.com/ai-generated-audios/www.hcplive.com/26f4a0d8-fa9e-4dac-87e2-b5fa04396611_1739924045892.b60fd8f4-a28d-43f5-8217-99de7d6f316e.mp3","is_visible":true,"documentGroupMapping":[{"_ref":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_type":"reference","_key":"937947c802da"}],"body":[{"alignment":"right","asset":{"_ref":"image-1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300-jpg","_type":"reference"},"widthP":35,"disableTextWrap":false,"disableLightBox":true,"_type":"figure","imgcaption":[{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Eric Simpson, MD","_key":"5a264222ce0e"}],"_type":"block","style":"normal","_key":"7762c6543f13"},{"children":[{"_type":"span","marks":[],"text":"Credit: Oregon Health \u0026 Science University","_key":"895a640ba0cc"}],"_type":"block","style":"normal","_key":"7d0f00fe2e3a","markDefs":[]}],"_key":"d7d39d5d819e"},{"children":[{"marks":[],"text":"Most patients with atopic dermatitis (AD) over 2 years of age clinically benefitted from 8 weeks of twice-daily ruxolitinib cream monotherapy.","_key":"e0789f3fa27b","_type":"span"},{"_type":"span","marks":["sup"],"text":"1","_key":"f24fa18c7cb0"}],"_type":"block","style":"normal","_key":"0ce7c5e6ef12","markDefs":[]},{"style":"normal","_key":"e47cd798d86d","markDefs":[],"children":[{"_type":"span","marks":[],"text":"These findings, from 3 randomized phase 3 studies, will be presented at the 2025 American Academy of Allergy, Asthma, and Immunology (AAAAI)/World Allergy Organization (WAO) Joint Congress, February 28-March 3, in San Diego, California, by Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health \u0026 Science University.","_key":"535175caef23"}],"_type":"block"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"“Following 8 weeks of twice-daily ruxolitinib cream monotherapy, the majority of patients aged ≥2 years met key clinically relevant AD endpoints. Efficacy and safety results were consistent across age groups,” Simpson and colleagues wrote.","_key":"11383fb48ee0"},{"_type":"span","marks":["sup"],"text":"1","_key":"54df65effdc4"}],"_type":"block","style":"normal","_key":"f11037d91ce3"},{"markDefs":[],"children":[{"text":"Simpson and colleagues evaluated ruxolitinib in children with AD aged 2 to 11 years in the TRuE-AD3 study (NCT04921969), and in adolescents and adults with AD in the TRuE-AD1 (NCT03745638) and TRuE-AD2 (NCT03745651) studies. Participants had to have an Investigator’s Global Assessment (IGA) score of 2/3, and a 3%–20% affected body surface area to qualify. They were randomized 2:2:1 to apply twice-daily 0.75% ruxolitinib cream, 1.5% ruxolitinib cream, or vehicle cream for 8 weeks. The studies assessed efficacy as proportions of patients who achieved IGA treatment success (IGA-TS) with a score of 0/1 with at least a 2-grade improvement from baseline, and at least a 75% or 90% improvement from baseline in the Eczema Area and Severity Index (EASI-75/EASI-90) at Week 8.","_key":"4ea927d32752","_type":"span","marks":[]},{"_type":"span","marks":["sup"],"text":"1","_key":"28847c47a950"}],"_type":"block","style":"normal","_key":"9a6dd11a5e70"},{"style":"normal","_key":"48baabd69916","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Altogether, the analysis includes data from 330 children, 236 adolescents, and 972 adults. The investigators found that at Week 8, significantly more (all ","_key":"e3f56a6d645f"},{"marks":["em"],"text":"P","_key":"79ea89d667f4","_type":"span"},{"_type":"span","marks":[],"text":" \u003c.01) children, adolescents, and adults who applied 1.5% ruxolitinib cream versus vehicle achieved IGA-TS (56.5% vs 10.8%, 50.6% vs 14.0%, 53.0% vs 10.9%, respectively), EASI-75 (67.2% vs 15.4%, 60.9% vs 34.9%, 62.2% vs 16.4%), and EASI-90 (43.5% vs 10.8%, 39.1% vs 7.0%, 44.9% vs 7.0%). In terms of safety, both strengths of ruxolitinib cream were well tolerated across age groups. There were few application site reactions and no safety findings suggestive of systemic JAK inhibition.","_key":"ab4772cbbb74"},{"_type":"span","marks":["sup"],"text":"1","_key":"959a4e4c27fc"}],"_type":"block"},{"_key":"4f4f5c5a7f6b","markDefs":[],"children":[{"text":"Other research set to be presented at the AAAAI/WAO Congress, led by Jessica Hui-Beckman, MD, from the National Jewish Health, found that infants who develop AD have skin barrier dysfunction in cheeks with delayed FLG processing, decreased protein-bound ceramides, and increased IL-18.","_key":"43b2e0646a2b","_type":"span","marks":[]},{"_type":"span","marks":["sup"],"text":"2","_key":"3978e8adae4b"}],"_type":"block","style":"normal"},{"_type":"block","style":"normal","_key":"d9438e39059b","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Among 18 babies, 8 developed atopic dermatitis. Children who developed atopic dermatitis had significantly increased transepidermal water loss from the birth visit (","_key":"ec9d47fc62fe"},{"marks":["em"],"text":"P","_key":"e6dab5370ec6","_type":"span"},{"_type":"span","marks":[],"text":" \u003c .05). Moreover, FLG breakdown products, such as sis-UCA, were significantly lower at birth (","_key":"4d17bc71b5bc"},{"_type":"span","marks":["em"],"text":"P","_key":"efd029db7994"},{"_key":"bc58bf49c63a","_type":"span","marks":[],"text":" \u003c .05) and 3 months ("},{"_type":"span","marks":["em"],"text":"P","_key":"dac30f7c91c9"},{"_type":"span","marks":[],"text":" = .0784) for children who later developed atopic dermatitis.","_key":"482df0c497c7"},{"_type":"span","marks":["sup"],"text":"2","_key":"bee6101b0a63"}]},{"_key":"4099c3284e02","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Additionally, amino acids originating from FLG, such as histidine (","_key":"66aa63f4f6c5"},{"_type":"span","marks":["em"],"text":"P","_key":"137ece58f271"},{"_type":"span","marks":[],"text":" \u003c .05) and glutamine (","_key":"52979dc6fc0a"},{"_type":"span","marks":["em"],"text":"P","_key":"f197996b6b26"},{"_type":"span","marks":[],"text":" \u003c .05 and ","_key":"54de21ae094e"},{"_key":"49dd77fca619","_type":"span","marks":["em"],"text":"P"},{"_type":"span","marks":[],"text":" \u003c .01) acid, were significantly lower at birth and 3 months, respectively, for children who developed atopic dermatitis. These children also had significantly decreased levels of protein-bound ceramides at 3 months (","_key":"387bc2177069"},{"marks":["em"],"text":"P","_key":"2835927c1fd6","_type":"span"},{"_type":"span","marks":[],"text":" \u003c .05). Furthermore, IL-18 was significantly increased at birth and even greater at 3 months (","_key":"0ac9f742b1dd"},{"_type":"span","marks":["em"],"text":"P","_key":"2f90a0248a22"},{"_type":"span","marks":[],"text":" \u003c .01) for children who developed atopic dermatitis.","_key":"61cee3e838d7"},{"text":"2","_key":"dfe5567d34e5","_type":"span","marks":["sup"]}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"REFERENCES\n1. Simpson E, Eichenfield L, Papp K, et al. Efficacy and Safety of Ruxolitinib Cream Monotherapy in Patients Aged 2 Years and Older With Mild-to-Moderate Atopic Dermatitis: Results From 3 Large Randomized Phase 3 Studies. Presented at: 2025 AAAAI/WAO Joint Congress, February 28-March 3. Abstract 613.","_key":"fc56b5949735"}],"_type":"block","style":"h6","_key":"609bfa719b33"},{"_key":"0cf73d6b7475","markDefs":[],"children":[{"_type":"span","marks":[],"text":"2. Hui-Beckmann, J, Goleva, E, Bronoff, A, et al. Early Life Cheek Skin Barrier Changes are Associated with Atopic Dermatitis Development. Poster will be presented at the AAAAI 2025 meeting in San Diego from February 28 – March 3.","_key":"ef416e84ef06"}],"_type":"block","style":"h6"}],"thumbnail":{"_type":"mainImage","alt":"Eric Simpson, MD, Frances J. Storrs, M.D. Medical Dermatology Professor, Dermatology, School of Medicine, Oregon Health \u0026 Science University","caption":"Ruxolitinib Shows Clinical Benefit in Children, Adults With Atopic Dermatitis","asset":{"_ref":"image-1a1faf343e8707fa301cf6dba84ec9f199dcad55-300x300-jpg","_type":"reference"}},"gptTakeaways":"• Ruxolitinib cream showed significant efficacy in treating atopic dermatitis in patients aged 2 years and older across three phase 3 studies.\n\n• Participants using 1.5% ruxolitinib cream achieved higher IGA treatment success and EASI improvements compared to vehicle cream users.\n\n• The treatment was well tolerated across age groups, with minimal application site reactions and no systemic JAK inhibition concerns.","summary":"Data from 3 pooled phase 3 studies in children, adolescents, and adults will be presented at the AAAI/WAO Joint Congress.","_type":"article","url":"ruxolitinib-clinical-benefit-children-adults-atopic-dermatitis","drugMentions":"{\n \"drug_mentions\": [\"ruxolitinib\"]\n}","articleType":"News","_id":"26f4a0d8-fa9e-4dac-87e2-b5fa04396611","_rev":"cID2mV6fSdv64jOtmJjSnD","authorMapping":[{"_ref":"d4c32d40-a161-4f01-8151-702eff7a6e75","_type":"reference","_key":"da0228eeb394"}],"authors":[{"displayName":"Victoria Johnson","url":"victoria-johnson"}],"ExcludeFromPubMedXML":false,"contentCategory":{"_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory","name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91","_updatedAt":"2023-01-17T17:54:09Z"},"title":"Ruxolitinib Shows Clinical Benefit in Children, Adults With Atopic Dermatitis","gptSummary":"Ruxolitinib cream, applied twice daily for 8 weeks, demonstrated significant clinical benefits for patients aged 2 years and older with atopic dermatitis (AD) across three phase 3 studies. The studies included children, adolescents, and adults, showing consistent efficacy and safety across age groups. Participants using 1.5% ruxolitinib cream achieved higher rates of Investigator’s Global Assessment treatment success and improvements in the Eczema Area and Severity Index compared to those using a vehicle cream. The treatment was well tolerated, with minimal application site reactions and no systemic JAK inhibition concerns.","documentGroup":{"docGroupArchive":false,"identifier":{"current":"american-academy-of-allergy-asthma-and-immunology-dermatology","_type":"slug"},"parent":{"_ref":"6f7fd681-6891-42d5-a963-e7cfdaba9d24","_type":"reference"},"_createdAt":"2025-01-10T16:46:52Z","_type":"documentGroup","name":"American Academy of Allergy, Asthma \u0026 Immunology - Dermatology","_id":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_rev":"lMqTJ7iiwxFTeHbLVRZGYG","_updatedAt":"2025-01-10T16:47:09Z"},"published":"2025-02-19T00:00:40.183Z","_createdAt":"2025-02-19T00:13:55Z","_updatedAt":"2025-02-19T00:27:15Z","taxonomyMapping":[{"_key":"d2a45e41aa6d","_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference"},{"_ref":"topic_atopic-dermatitis","_type":"reference","_key":"c8c89072a11e"},{"_ref":"topic_dermatology","_type":"reference","_key":"5ca879c53109"},{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference","_key":"490cc8762c4e"},{"_ref":"6e1a5e9c-c5e9-4d19-b803-e00d93da7863","_type":"reference","_key":"5d114280c2db"}]},{"documentGroupMapping":[{"_key":"a9909061acbc","_ref":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_type":"reference"}],"summary":"A study found many patients with chronic spontaneous urticaria need add-on or higher-dose therapies, revealing gaps in treatment. Findings will be presented at AAAAI 2025.","ExcludeFromPubMedXML":false,"seoTag":["allergy","dermatology","urticaria","chronic spontaneous urticaria"],"authorMapping":[{"_ref":"c91bc665-dc9f-464d-9ec0-b26014d056e3","_type":"reference","_key":"926954a919df"}],"is_visible":true,"_type":"article","_updatedAt":"2025-02-18T21:31:16Z","url":"unmet-need-for-advanced-chronic-spontaneous-urticaria-treatments-highlighted-in-study","published":"2025-02-18T20:49:00.000Z","authors":[{"displayName":"Chelsie Derman","url":"chelsie-derman"}],"body":[{"alt":"Jonathan Bernstein, MD, FAAAAI I Credit: Bernstein Allergy Group","widthP":32,"disableLightBox":true,"imgcaption":[{"_key":"5cccbe5d047b","markDefs":[],"children":[{"text":"Jonathan Bernstein, MD, FAAAAI","_key":"a3a1e19b7c17","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"_key":"8f5c9a302d9f","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Credit: Bernstein Allergy Group","_key":"6270ecefc5e8"}],"_type":"block","style":"normal"}],"_key":"264ddb76592a","alignment":"right","asset":{"_ref":"image-c3aa3c1592a69f9e41f5005a3d21ee1879cbef77-704x762-png","_type":"reference"},"disableTextWrap":false,"_type":"figure"},{"_key":"4f774d41c5a8","markDefs":[{"blank":true,"_type":"link","href":"https://www.hcplive.com/conference/american-academy-of-allergy-asthma-and-immunology-dermatology","_key":"eb437431b889"}],"children":[{"_type":"span","marks":[],"text":"A study examining treatment patterns found patients on advanced therapies for chronic spontaneous urticaria often had add-on treatments, switched treatments, and took higher than FDA-approved doses—all indicating an unmet need for advanced treatment options in chronic spontaneous urticaria.","_key":"bf1c4cc3c5e4"},{"_key":"6c12bb49c1c1","_type":"span","marks":["sup"],"text":"1"},{"_type":"span","marks":[],"text":" The findings will be presented at the ","_key":"5590f9a8fbb7"},{"_type":"span","marks":["eb437431b889"],"text":"2025 American Academy of Allergy, Asthma, \u0026 Immunology (AAAAI)","_key":"b26ad848b509"},{"text":" annual meeting in San Diego from February 28 – March 3.","_key":"0fdddf3383af","_type":"span","marks":[]}],"_type":"block","style":"normal"},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"These chronic hives often require intense treatment to control symptoms. Omalizumab is the only FDA-approved advanced treatment for chronic spontaneous urticaria, but less aggressive treatments can manage itchiness.","_key":"60cf146b7903"}],"_type":"block","style":"normal","_key":"88eb38ac0f2b"},{"style":"normal","_key":"7d43c40c1718","markDefs":[],"children":[{"marks":[],"text":"If nonprescription antihistamines do not work, a healthcare professional may recommend their patient to take montelukast, doxepin, ranitidine, or omalizumab.","_key":"4b58bec292af","_type":"span"},{"_key":"ce618870bdd0","_type":"span","marks":["sup"],"text":"2"},{"_type":"span","marks":[],"text":" For patients who still do not find relief with these drugs, medication that calms the overactive immune system, such as cyclosporine, tacrolimus, hydroxychloroquine, and mycophenolate, could be a more effective alternative.","_key":"f895dc5bc71f"}],"_type":"block"},{"_type":"block","style":"normal","_key":"41c67c25a8a1","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Patients with chronic spontaneous urticaria can also turn to nonmedication options, such as avoiding triggers, such as foods, medicines, pollen, pet dander, latex, or insect stings. They can also apply cold to the itchy area, take a cool shower or bath, apply an anti-itch cream or lotion, wear loose, smooth cotton clothing, and protect skin from the sun by using sunscreen.","_key":"f19294e2f211"}]},{"children":[{"_type":"span","marks":[],"text":"With the available treatment options, investigators, led by Jonathan Bernstein, MD, FAAAAI, from the University of Cincinnati College of Medicine Division of Rheumatology, Allergy and Immunology and Be, conducted a study to describe real-world advanced treatment patterns for chronic spontaneous urticaria.","_key":"c1a9d5b95fd4"},{"_type":"span","marks":["sup"],"text":"1","_key":"9545dde6e6d1"},{"_type":"span","marks":[],"text":" Using the IQVIA PharMetrics claims database, investigators identified patients aged 12 – 64 years who initiated advanced therapy, such as systemic immunosuppressant, systemic anti-inflammatory drugs, or omalizumab, ≤ 14 days from receiving a chronic spontaneous urticaria diagnosis between 2021 and 2022. The first dispensation was marked as the index date.","_key":"14656c3225e4"}],"_type":"block","style":"normal","_key":"c1bf0dd2cfca","markDefs":[]},{"markDefs":[],"children":[{"_type":"span","marks":[],"text":"Patients were included if they had 1 year of baseline data before the index date, ≥ 2 diagnosis codes for chronic spontaneous urticaria ≥ 6 weeks apart, no advanced therapy use, and ≥ 1 year of follow-up. During the follow-up period, the team assessed add-on treatment, treatment switching, and dose augmentation out of the FDA-approved dosages for omalizumab only, stratified by index treatment class.","_key":"92bd6fd177dc"}],"_type":"block","style":"normal","_key":"4afdd6ebdbbf"},{"markDefs":[],"children":[{"marks":[],"text":"In total, 1322 patients participated in the study. Among the sample, the mean age was 40.95 years, and 77.3% were female. The most dispensed advanced therapy was omalizumab (88.1%), followed by systemic anti-inflammatory agents (8%) and systemic immunosuppressants (3.9%).","_key":"2dee12234a59","_type":"span"}],"_type":"block","style":"normal","_key":"5481fa566087"},{"_type":"block","style":"normal","_key":"6a13c781d95c","markDefs":[],"children":[{"_type":"span","marks":[],"text":"Approximately half of the patients on omalizumab (55.9%), systemic anti-inflammatory (51.9%), and systemic immunosuppressant (52.9%) treatments used add-on therapies. Moreover, treatment switching occurred in 51% of patients on systemic immunosuppressants, 44.3% on systemic anti-inflammatories, and 16.5% on omalizumab.","_key":"334bdc113e86"}]},{"markDefs":[],"children":[{"_key":"d6c9ba36c596","_type":"span","marks":[],"text":"As for augmentation, 26.2% of patients treated with omalizumab took a dose greater than the FDA-approved dosage."}],"_type":"block","style":"normal","_key":"1ea0f0bcf244"},{"_type":"block","style":"normal","_key":"8aec230425bb","markDefs":[],"children":[{"text":"“Add-on treatments, treatment switching, and treatment with higher than FDA-approved doses (omalizumab only) suggest there is an unmet need for alternative advanced treatment options in [chronic spontaneous urticaria],\" investigators concluded.","_key":"c91d2fd87bad","_type":"span","marks":[]}]},{"_type":"block","style":"h6","_key":"2f9ae711de96","markDefs":[],"children":[{"text":"References","_key":"7c2dd9550a66","_type":"span","marks":[]}]},{"_type":"block","style":"h6","_key":"9693b6e78d70","listItem":"number","markDefs":[],"children":[{"_key":"af6f51c9ece9","_type":"span","marks":[],"text":"Bernstein, J, Thomas, R, Chuang, C, et al. Real-world Treatment Patterns Amongst Patients with Chronic Spontaneous Urticaria Initiating Advanced Therapies. Poster will be presented at the 2025 AAAAI annual meeting in San Diego from February 28 – March 3."}],"level":1},{"level":1,"_type":"block","style":"h6","_key":"59e678e18880","listItem":"number","markDefs":[{"blank":true,"_type":"link","href":"https://www.mayoclinic.org/diseases-conditions/chronic-hives/diagnosis-treatment/drc-20352723","_key":"0c5b76477697"}],"children":[{"_key":"e7a9d6b2fa71","_type":"span","marks":[],"text":"Chronic Hives. Mayo Clinic. "},{"text":"https://www.mayoclinic.org/diseases-conditions/chronic-hives/diagnosis-treatment/drc-20352723","_key":"4a4c13f97a12","_type":"span","marks":["0c5b76477697"]},{"_type":"span","marks":[],"text":". Accessed February 18, 2025.","_key":"bbd8394631d0"}]},{"_key":"1b27b2b66f4c","markDefs":[],"children":[{"marks":[],"text":"","_key":"5bc7cca15d6e","_type":"span"}],"_type":"block","style":"h6"},{"style":"normal","_key":"6065108a9b2f","markDefs":[],"children":[{"_key":"a108c62f786f","_type":"span","marks":[],"text":"\n"}],"_type":"block"}],"articleType":"News","_rev":"Fd1jDX9jbPHQLM4ybifjpD","_createdAt":"2025-02-18T20:53:41Z","_id":"f9726b00-689a-4cba-9885-c3757f059fd9","taxonomyMapping":[{"_ref":"00c35849-3d97-4901-be93-6e229c2a844d","_type":"reference","_key":"9920c67bdd56"},{"_ref":"703a1bdf-1645-43ac-9e1b-55e382091532","_type":"reference","_key":"794714b5861c"},{"_key":"8bebd94f9b67","_ref":"topic_dermatology","_type":"reference"},{"_ref":"6e1a5e9c-c5e9-4d19-b803-e00d93da7863","_type":"reference","_key":"7b6281704b39"}],"documentGroup":{"docGroupArchive":false,"identifier":{"current":"american-academy-of-allergy-asthma-and-immunology-dermatology","_type":"slug"},"parent":{"_ref":"6f7fd681-6891-42d5-a963-e7cfdaba9d24","_type":"reference"},"_createdAt":"2025-01-10T16:46:52Z","_type":"documentGroup","name":"American Academy of Allergy, Asthma \u0026 Immunology - Dermatology","_id":"53da29fc-7670-4d0b-a550-0424f07a8e8a","_rev":"lMqTJ7iiwxFTeHbLVRZGYG","_updatedAt":"2025-01-10T16:47:09Z"},"title":"Unmet Need for Advanced Chronic Spontaneous Urticaria Treatments Highlighted in Study","drugMentions":"{\n \"drug_mentions\": [\"Omalizumab\", \"montelukast\", \"doxepin\", \"ranitidine\", \"cyclosporine\", \"tacrolimus\", \"hydroxychloroquine\", \"mycophenolate\"]\n}","contentCategory":{"_createdAt":"2020-05-26T14:28:02Z","_rev":"fJ4FMwqo4VySHpOtVufzWi","_type":"contentCategory","name":"Articles","_id":"037a489b-09e7-4a58-a2cb-e490b6d14b91","_updatedAt":"2023-01-17T17:54:09Z"},"thumbnail":{"_type":"mainImage","alt":"Jonathan Bernstein, MD, FAAAAI I Credit: Bernstein Allergy Group","caption":"Jonathan Bernstein, MD, FAAAAI\nCredit: Bernstein Allergy Group","asset":{"_ref":"image-c3aa3c1592a69f9e41f5005a3d21ee1879cbef77-704x762-png","_type":"reference"}}}],"tiData":[{"id":"8ed9c3f5-b964-4cc3-9eee-0e3007abf905","brandName":"PhysiciansPractice","dataType":"per","title":"SimulatED™: Diagnosing and Treating Alzheimer’s Disease in the Modern Era","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/ddcpnrxgcu4a-Simulated_ADTICatalog750x361.png","description":"Dani Cabral, MD; Marwan N. Sabbagh, MD, FAAN, FANA","releaseDate":"2024-07-31","expirationDate":"2025-07-31","creditType":"CME,NCPD","creditAmount":"1 to 3","created_at":"2025-02-10T12:06:14.965696+00:00","TI_id":"9b93d177-d205-41d1-9789-518421bc418c","slug":"simulated-diagnosing-and-treating-alzheimers-disease-in-the-modern-era","delReference":true,"contentTypeLabel":"Case-based Simulation","activity-type":"[\"Online Activity\"]","specialty":"[\"Internal Medicine\",\"Neurology\",\"New Drugs\",\"Primary Care\",\"Psychiatry\"]","creditCertificate":"1.25","courseEndDate":"2025-08-01T03:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null,"sortOrder":1},{"id":"f41bd0a4-e0ec-4521-860b-25fc88ab21f9","brandName":"PhysiciansPractice","dataType":"per","title":"Cases and Conversations™: A Horizon View of Continuous Monitoring Systems for Diabetes Management","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/6y9k5j6nl3md-ACP25_CGM_TICatalog750x3612x1.png","description":"April 3, 2025","releaseDate":"","expirationDate":"","creditType":"CME","creditAmount":"1 to 3","created_at":"2025-02-10T12:06:15.149708+00:00","TI_id":"4342224e-376d-4113-affa-d6ba19e38a18","slug":"diabetes-management","delReference":true,"contentTypeLabel":"In-Person + Virtual Event","activity-type":"[\"In Person\"]","specialty":"[\"Endocrinology Diabetes \u0026 Metabolism\",\"Internal Medicine\",\"New Drugs\",\"Primary Care\"]","creditCertificate":"","courseEndDate":"2025-04-04T03:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null},{"id":"d14e8a46-ff99-4fca-9bf9-6b93aaa75ac1","brandName":"PhysiciansPractice","dataType":"per","title":"A Tethered Approach to Type 2 Diabetes Care – Connecting Insulin Regimens with Digital Technology","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/9f7ffzgm0g6g-ACP_TICatalog750x3612x.png","description":"Robert S. Busch, MD, FACE; Javier Morales, MD, FACP, FACE; Lucia M. Novak, MSN, ANP-BC, BC-ADM","releaseDate":"2024-04-30","expirationDate":"2025-04-30","creditType":"CME,NCPD","creditAmount":"1 to 3","created_at":"2025-02-10T12:06:15.077819+00:00","TI_id":"81798092-b4f8-4dfa-9a1b-0e6cb84307b0","slug":"a-tethered-approach-to-type-2-diabetes-care-connecting-insulin-regimens-with-digital-technology-cqdv","delReference":true,"contentTypeLabel":"Video","activity-type":"[\"Online Activity\"]","specialty":"[\"Endocrinology Diabetes \u0026 Metabolism\",\"Family Medicine\",\"Internal Medicine\",\"New Drugs\",\"Primary Care\"]","creditCertificate":"1.5","courseEndDate":"2025-05-01T03:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null},{"id":"2aef7e83-78fc-4ab5-9ee0-940bb46c07d0","brandName":"PhysiciansPractice","dataType":"per","title":"Surv.AI Says™: What Clinicians and Patients Are Saying About Glucose Management in the Technology Age","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/0u97uvvry562-ACP_Survai_Archive_TICatalog750x361.png","description":"Javier Morales, MD, FACP, FACE; Diana Isaacs, PharmD, BCPS, BC-ADM, BCACP, CDCES, FADCES, FCCP; E. Seth Kramer, DO, MPH\n","releaseDate":"2024-04-30","expirationDate":"2025-04-30","creditType":"CME,NCPD","creditAmount":"1 to 3","created_at":"2025-02-10T12:06:15.114223+00:00","TI_id":"d20e1692-7d95-47f7-9ce7-726925ab6104","slug":"survey-says-what-are-clinicians-and-patients-saying-about-glucose-management-in-the-technology-age","delReference":true,"contentTypeLabel":"Video","activity-type":"[\"Online Activity\"]","specialty":"[\"Internal Medicine\",\"Family Medicine\",\"Primary Care\",\"Endocrinology Diabetes \u0026 Metabolism\"]","creditCertificate":"1.5","courseEndDate":"2025-05-01T03:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null},{"id":"d6dcdce4-ecbe-4b82-9024-357b9b5a2318","brandName":"PhysiciansPractice","dataType":"per","title":"Clinical ShowCase™: Forming a Personalized Treatment Plan for a Patient With ANCA-Associated Vasculitis","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/j4x6y3g4v958-TICatalog750x3612x311.png","description":"Anisha Dua MD, MPH; Brian Jaros, MD","releaseDate":"2024-07-30","expirationDate":"2025-07-30","creditType":"CME","creditAmount":"\u003c1","created_at":"2025-02-10T12:06:15.013165+00:00","TI_id":"32cc5660-24f8-40d8-b3f4-4e119ecb5a82","slug":"clinical-showcase-forming-a-personalized-treatment-plan-for-a-patient-with-anca-associated-vasculitis","delReference":true,"contentTypeLabel":"Case-based Simulation","activity-type":"[\"Online Activity\"]","specialty":"[\"Internal Medicine\",\"Rare Diseases\",\"Rheumatology\"]","creditCertificate":"0.25","courseEndDate":"2025-07-31T03:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null},{"id":"724b2643-978e-4be0-9b3e-e15aacc39b41","brandName":"PhysiciansPractice","dataType":"per","title":"Addressing Healthcare Inequities: Tailoring Cancer Screening Plans to Address Inequities in Care","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/s3ftts655gmw-TICatalog750x3612x271.png","description":"Pamela Ganschow, MD; Gautum Agarwal, MD; Folasade (Fola) P. May, MD, PhD, MPhil","releaseDate":"2024-07-31","expirationDate":"2025-07-31","creditType":"CME,NCPD","creditAmount":"1 to 3","created_at":"2025-02-10T12:06:14.928844+00:00","TI_id":"61e103a7-e1a3-4097-8ce5-37591c3c8f19","slug":"addressing-healthcare-inequities-tailoring-cancer-screening-plans-to-address-inequities-in-care","delReference":true,"contentTypeLabel":"Video","activity-type":"[\"Online Activity\"]","specialty":"[\"Family Medicine\",\"Gastroenterology\",\"Internal Medicine\",\"Primary Care\",\"Women's Health\"]","creditCertificate":"1.25","courseEndDate":"2025-08-01T03:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null},{"id":"7c9c5349-b821-419d-8155-ac71d963bb15","brandName":"PhysiciansPractice","dataType":"per","title":"Patient, Provider \u0026 Caregiver Connection™: Understanding the Patient Journey to Provide Personalized Care for Generalized Pustular Psoriasis","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/9ybisyhjkwg9-TICatalog750x3612x1212.png","description":"Tina Bhutani, MD, MAS, FAAD; Jason E. Hawkes MD, MS","releaseDate":"2024-10-28","expirationDate":"2025-10-28","creditType":"CME,NCPD","creditAmount":"1 to 3","created_at":"2025-02-10T12:06:14.881383+00:00","TI_id":"e4750727-9e77-4923-b15b-8d38a19b1b6d","slug":"patient-provider-caregiver-connection-understanding-the-patient-journey-to-provide-personalized-care-for-generalized-pustular-psoriasis","delReference":true,"contentTypeLabel":"Video","activity-type":"[\"Online Activity\"]","specialty":"[\"Dermatology\",\"Emergency Medicine\",\"Immunology\",\"Internal Medicine\",\"New Drugs\",\"Primary Care\"]","creditCertificate":"1.5","courseEndDate":"2025-10-29T03:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null},{"id":"78417c0d-8dcf-4912-9555-8f4660d32529","brandName":"PhysiciansPractice","dataType":"per","title":"Cases and Conversations™: Applying Best Practices to Prevent Shingles in Your Practice","thumbnail":"https://d36ai2hkxl16us.cloudfront.net/thoughtindustries/image/upload/v1/course-uploads/07c0d4e1-23aa-4e1a-8c5f-f2569da581c0/k7tj8wih6443-TICatalog750x3612x491.png","description":"Paul G. Auwaerter, MD, MBA; Paul P. Doghramji, MD, FAAFP; Aruna Subramanian, MD","releaseDate":"2024-11-08","expirationDate":"2025-11-08","creditType":"CME,NCPD","creditAmount":"1 to 3","created_at":"2025-02-10T12:06:14.838319+00:00","TI_id":"78cf1f5a-61ee-4553-9497-fe4c5faebe43","slug":"cases-and-conversations-applying-best-practices-to-prevent-shingles-in-your-practice-x7ap","delReference":true,"contentTypeLabel":"Video","activity-type":"[\"Online Activity\"]","specialty":"[\"Dermatology\",\"Family Medicine\",\"Infectious Diseases\",\"Internal Medicine\",\"Neurology\",\"Primary Care\"]","creditCertificate":"1.5","courseEndDate":"2025-11-09T04:59:59.999+00:00","cventUrl":"","eventData":null,"imageUrl":null}]}},"__N_SSG":true},"page":"/","query":{},"buildId":"0zFRHeX4gm9NzHq9OuiA0","isFallback":false,"gsp":true,"appGip":true,"scriptLoader":[]}</script></body></html>