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<!DOCTYPE html PUBLIC "-//W3C//DTD HTML 4.01 Transitional//EN" "http://www.w3.org/TR/html4/loose.dtd"> <html lang="en"> <head> <meta http-equiv="Content-Type" content="text/html; charset=UTF-8"> <title>SEC FORM 4</title> <style type="text/css"> .FormData {color: blue; background-color: white; font-size: small; font-family: Times, serif;} .FormDataC {color: blue; background-color: white; font-size: small; font-family: Times, serif; text-align: center;} .FormDataR {color: blue; background-color: white; font-size: small; font-family: Times, serif; text-align: right;} .SmallFormData {color: blue; background-color: white; font-size: x-small; font-family: Times, serif;} .FootnoteData {color: green; background-color: white; font-size: x-small; font-family: Times, serif;} .RemarksData { padding: 0; margin: 0 0 4px; } .FormNumText {font-size: small; font-weight: bold; font-family: arial, helvetica, sans-serif;} .FormAttention {font-size: medium; font-weight: bold; font-family: helvetica;} .FormText {font-size: small; font-weight: normal; font-family: arial, helvetica, sans-serif; text-align: left;} .FormTextR {font-size: small; font-weight: normal; font-family: arial, helvetica, sans-serif; text-align: right;} .FormTextC {font-size: small; font-weight: normal; font-family: arial, helvetica, sans-serif; text-align: center; margin: 4px;} .FormEMText {font-size: medium; font-style: italic; font-weight: normal; font-family: arial, helvetica, sans-serif;} .FormULText {font-size: medium; text-decoration: underline; font-weight: normal; font-family: arial, helvetica, sans-serif;} .SmallFormText {font-size: xx-small; font-family: arial, helvetica, sans-serif; text-align: left;} .SmallFormTextR {font-size: xx-small; font-family: arial, helvetica, sans-serif; text-align: right;} .SmallFormTextC {font-size: xx-small; font-family: arial, helvetica, sans-serif; text-align: center;} .MedSmallFormText {font-size: x-small; font-family: arial, helvetica, sans-serif; text-align: left;} .FormTitle {font-size: medium; font-family: arial, helvetica, sans-serif; font-weight: bold; margin: 0;} .FormTitle1 {font-size: small; font-family: arial, helvetica, sans-serif; font-weight: bold; border-top: black thick solid;} .FormTitle2 {font-size: small; font-family: arial, helvetica, sans-serif; font-weight: bold;} .FormTitle3 {font-size: small; font-family: arial, helvetica, sans-serif; font-weight: bold; padding-top: 2em; padding-bottom: 1em;} .SectionTitle {font-size: small; text-align: left; font-family: arial, helvetica, sans-serif; font-weight: bold; border-top: gray thin solid; border-bottom: gray thin solid;} .FormName {font-size: large; font-family: arial, helvetica, sans-serif; font-weight: bold;} .CheckBox {text-align: center; width: 5px; cell-spacing: 0; padding: 0 3 0 3; border-width: thin; border-style: solid; border-color: black:} .sr-only {position: absolute; width: 1px; height: 1px; padding: 0; margin: -1px; overflow: hidden; clip: rect(0, 0, 0, 0); border: 0;} body {background: white;} </style> </head> <body><main>SEC Form 4 <table width="100%" border="0" cellspacing="0" cellpadding="4"> <tr> <td width="20%" colspan="2" valign="top" align="center" class="FormName">FORM 4</td> <td rowspan="2" width="60%" valign="middle" align="center"> UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 <h1 class="FormTitle">STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP</h1> Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940 </td> <td rowspan="2" width="20%" valign="top" align="center"><table width="100%" border="1" summary="OMB Approval Status Box"> <caption class="FormTextC">OMB APPROVAL</caption> <tr><td><table width="100%" border="0" summary="OMB Interior Box"> <tr> <th class="SmallFormText" colspan="3">OMB Number:</th> <td class="SmallFormTextR">3235-0287</td> </tr> <tr><th class="SmallFormText" colspan="4">Estimated average burden</th></tr> <tr> <th class="SmallFormText" colspan="3">hours per response:</th> <td class="SmallFormTextR">0.5</td> </tr> </table></td></tr> </table></td> </tr> <tr valign="middle"> <td><table width="100%" border="1" cellpadding="0" cellspacing="0"><tr><td>聽聽</td></tr></table></td> <td class="SmallFormText">Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).</td> </tr> <tr valign="middle"> <td><table width="100%" border="1" cellpadding="0" cellspacing="0"><tr><td>聽聽</td></tr></table></td> <td class="SmallFormText"> Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10. </td> </tr> </table> <table width="100%" border="1" cellspacing="0" cellpadding="4"> <tr> <td rowspan="3" width="35%" valign="top"> 1. Name and Address of Reporting Person*<table border="0" width="100%"><tr><td><a href="https://sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0001677618">VESSEY RUPERT</a></td></tr></table> <hr width="98%"> <table border="0" width="100%"><tr> <td width="33%" class="MedSmallFormText">(Last)</td> <td width="33%" class="MedSmallFormText">(First)</td> <td width="33%" class="MedSmallFormText">(Middle)</td> </tr></table> <table border="0" width="100%"> <tr><td>614 MCKINLEY PL NE</td></tr> <tr><td></td></tr> </table> <hr width="98%"> (Street)<table border="0" width="100%"><tr> <td width="33%">MINNEAPOLIS</td> <td width="33%">MN</td> <td width="33%">55413</td> </tr></table> <hr width="98%"> <table border="0" width="100%"><tr> <td width="33%" class="MedSmallFormText">(City)</td> <td width="33%" class="MedSmallFormText">(State)</td> <td width="33%" class="MedSmallFormText">(Zip)</td> </tr></table> </td> <td width="35%" valign="top"> 2. Issuer Name and Ticker or Trading Symbol <a href="https://sec.gov/cgi-bin/browse-edgar?action=getcompany&CIK=0000842023">BIO-TECHNE Corp</a> [ TECH ] </td> <td rowspan="2" valign="top"> 5. Relationship of Reporting Person(s) to Issuer (Check all applicable)<table border="0" width="100%"> <tr> <td width="15%" align="center">X</td> <td width="35%" class="MedSmallFormText">Director</td> <td width="15%" align="center"></td> <td width="35%" class="MedSmallFormText">10% Owner</td> </tr> <tr> <td align="center"></td> <td class="MedSmallFormText">Officer (give title below)</td> <td align="center"></td> <td class="MedSmallFormText">Other (specify below)</td> </tr> <tr><td colspan="4" align="center"></td></tr> </table> </td> </tr> <tr><td valign="top"> 3. Date of Earliest Transaction (Month/Day/Year) 10/24/2024 </td></tr> <tr> <td valign="top"> 4. If Amendment, Date of Original Filed (Month/Day/Year) </td> <td valign="top"> 6. Individual or Joint/Group Filing (Check Applicable Line) <table border="0" width="100%"> <tr> <td width="15%" align="center">X</td> <td width="85%" class="MedSmallFormText">Form filed by One Reporting Person</td> </tr> <tr> <td width="15%" align="center"></td> <td width="85%" class="MedSmallFormText">Form filed by More than One Reporting Person</td> </tr> </table> </td> </tr> </table> <table width="100%" border="1" cellspacing="0" cellpadding="4"> <caption class="FormTextC">Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned</caption> <thead> <tr> <th width="36%" valign="top" rowspan="2" align="left" class="MedSmallFormText">1. Title of Security (Instr. 3) </th> <th width="6%" valign="top" rowspan="2" align="left" class="SmallFormText">2. Transaction Date (Month/Day/Year)</th> <th width="5%" valign="top" rowspan="2" align="left" class="SmallFormText">2A. Deemed Execution Date, if any (Month/Day/Year)</th> <th width="7%" valign="top" colspan="2" align="left" class="SmallFormText">3. Transaction Code (Instr. 8) </th> <th width="19%" valign="top" colspan="3" align="left" class="SmallFormText">4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) </th> <th width="11%" valign="top" rowspan="2" align="left" class="SmallFormText">5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) </th> <th width="9%" valign="top" rowspan="2" align="left" class="SmallFormText">6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) </th> <th width="8%" valign="top" rowspan="2" align="left" class="SmallFormText">7. Nature of Indirect Beneficial Ownership (Instr. 4) </th> </tr> <tr> <th width="4%" align="center" class="SmallFormText">Code</th> <th width="3%" align="center" class="SmallFormText">V</th> <th width="8%" align="center" class="SmallFormText">Amount</th> <th width="5%" align="center" class="SmallFormText">(A) or (D)</th> <th width="6%" align="center" class="SmallFormText">Price</th> </tr> </thead> <tbody><tr> <td align="left">Common Stock</td> <td align="center">10/24/2024</td> <td align="center"></td> <td align="center">A</td> <td align="center"></td> <td align="center">1,462</td> <td align="center">A</td> <td align="center"> $0 </td> <td align="center">9,347</td> <td align="center">D</td> <td align="left"></td> </tr></tbody> </table> <table width="100%" border="1" cellspacing="0" cellpadding="4"> <caption class="FormTextC"> Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities) </caption> <thead> <tr> <th width="13%" valign="top" rowspan="2" align="left" class="SmallFormText">1. Title of Derivative Security (Instr. 3) </th> <th width="5%" valign="top" rowspan="2" align="left" class="SmallFormText">2. Conversion or Exercise Price of Derivative Security </th> <th width="5%" valign="top" rowspan="2" align="left" class="SmallFormText">3. Transaction Date (Month/Day/Year)</th> <th width="5%" valign="top" rowspan="2" align="left" class="SmallFormText">3A. Deemed Execution Date, if any (Month/Day/Year)</th> <th width="9%" valign="top" colspan="2" align="left" class="SmallFormText">4. Transaction Code (Instr. 8) </th> <th width="10%" valign="top" colspan="2" align="left" class="SmallFormText">5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) </th> <th width="9%" valign="top" colspan="2" align="left" class="SmallFormText">6. Date Exercisable and Expiration Date (Month/Day/Year)</th> <th width="17%" valign="top" colspan="2" align="left" class="SmallFormText">7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) </th> <th width="6%" valign="top" rowspan="2" align="left" class="SmallFormText">8. Price of Derivative Security (Instr. 5) </th> <th width="6%" valign="top" rowspan="2" align="left" class="SmallFormText">9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) </th> <th width="6%" valign="top" rowspan="2" align="left" class="SmallFormText">10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) </th> <th width="7%" valign="top" rowspan="2" align="left" class="SmallFormText">11. Nature of Indirect Beneficial Ownership (Instr. 4) </th> </tr> <tr> <th width="4%" valign="bottom" align="center" class="SmallFormText">Code</th> <th width="4%" valign="bottom" align="center" class="SmallFormText">V</th> <th width="5%" valign="bottom" align="center" class="SmallFormText">(A)</th> <th width="5%" valign="bottom" align="center" class="SmallFormText">(D)</th> <th width="5%" valign="bottom" align="center" class="SmallFormText">Date Exercisable</th> <th width="4%" valign="bottom" align="center" class="SmallFormText">Expiration Date</th> <th width="10%" valign="bottom" align="center" class="SmallFormText">Title</th> <th width="7%" valign="bottom" align="center" class="SmallFormText">Amount or Number of Shares</th> </tr> </thead> <tbody> <tr> <td align="left">Stock Options (Right to Buy)</td> <td align="center"> $50.41 </td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center">10/24/2020</td> <td align="center">10/24/2029</td> <td align="center">Common Stock</td> <td align="center">8,044</td> <td align="center"></td> <td align="center">8,044</td> <td align="center">D</td> <td align="left"></td> </tr> <tr> <td align="left">Stock Options (Right to Buy)</td> <td align="center"> $52.32 </td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center">10/24/2019</td> <td align="center">10/25/2029</td> <td align="center">Common Stock</td> <td align="center">2,352</td> <td align="center"></td> <td align="center">2,352</td> <td align="center">D</td> <td align="left"></td> </tr> <tr> <td align="left">Stock Options (Right to Buy)</td> <td align="center"> $63.92 </td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center">10/28/2021</td> <td align="center">10/29/2030</td> <td align="center">Common Stock</td> <td align="center">6,028</td> <td align="center"></td> <td align="center">6,028</td> <td align="center">D</td> <td align="left"></td> </tr> <tr> <td align="left">Stock Options (Right to Buy)</td> <td align="center"> $128.81 </td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center">10/27/2022</td> <td align="center">10/28/2031</td> <td align="center">Common Stock</td> <td align="center">2,532</td> <td align="center"></td> <td align="center">2,532</td> <td align="center">D</td> <td align="left"></td> </tr> <tr> <td align="left">Stock Options (Right to Buy)</td> <td align="center"> $73.94 </td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center">10/26/2023</td> <td align="center">10/27/2032</td> <td align="center">Common Stock</td> <td align="center">3,460</td> <td align="center"></td> <td align="center">3,460</td> <td align="center">D</td> <td align="left"></td> </tr> <tr> <td align="left">Stock Options (Right to Buy)</td> <td align="center"> $61.51 </td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center"></td> <td align="center">10/24/2024</td> <td align="center">10/26/2033</td> <td align="center">Common Stock</td> <td align="center">3,937</td> <td align="center"></td> <td align="center">3,937</td> <td align="center">D</td> <td align="left"></td> </tr> <tr> <td align="left">Stock Options (Right to Buy)</td> <td align="center"> $68.37 </td> <td align="center">10/24/2024</td> <td align="center"></td> <td align="center">A</td> <td align="center"></td> <td align="center">3,511</td> <td align="center"></td> <td align="center"> (1) </td> <td align="center">10/24/2034</td> <td align="center">Common Stock</td> <td align="center">3,511</td> <td align="center"> $0 </td> <td align="center">3,511</td> <td align="center">D</td> <td align="left"></td> </tr> </tbody> </table> <table border="0" width="100%"> <tr><td class="MedSmallFormText">Explanation of Responses:</td></tr> <tr><td class="FootnoteData">1. The option vests on the earlier of the one year anniversary of the grant date (10/24/2024) or the date of Bio-Techne's 2025 annual meeting of shareholders.</td></tr> </table> <table width="100%" border="0"> <tr> <td width="60%"></td> <td width="20%">/s/ Andrew Nick as Attorney-in-Fact for Rupert Vessey pursuant to Power of Attorney previously filed</td> <td width="20%">10/28/2024</td> </tr> <tr> <td></td> <td class="MedSmallFormText">** Signature of Reporting Person</td> <td class="MedSmallFormText">Date</td> </tr> </table> Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. * If the form is filed by more than one reporting person, see Instruction 4 (b)(v). ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.</main></body> </html>