CINXE.COM

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class="pw_menu_block"> <div class="et-pathways-topics pathway_menu_items"> <div class="pathways-block"> <h5 class="pathways-title"> <a href="/pathways">Interactive Pathways & Processes</a></h5> <ul class="pathways-ul" data-count="10" id="menuPathways"> <li class="pathways-li "> <form id="pathways_cancer_pathways" action="/pathways/cancer" method="post"> <a href="/pathways/cancer" data-form="pathways_cancer_pathways" class="pathway_link"> <span class="icon-"> Cancer Pathways </span> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </li> <li class="pathways-li "> <form id="pathways_cardiovascular_biology_pathways" action="/pathways/cardiovascular-biology" method="post"> <a href="/pathways/cardiovascular-biology" data-form="pathways_cardiovascular_biology_pathways" class="pathway_link"> <span class="icon-"> Cardiovascular Biology Pathways </span> </a> <input type="hidden" name="pw_parent" value="cardiovascular"> </form> </li> <li class="pathways-li "> <form id="pathways_development_pathways" action="/pathways/developmental-biology" method="post"> <a href="/pathways/developmental-biology" data-form="pathways_development_pathways" class="pathway_link"> <span class="icon-"> Development Pathways </span> </a> <input type="hidden" name="pw_parent" value="developmental-biology"> </form> </li> <li class="pathways-li "> <form id="pathways_glycobiology_pathways" action="/pathways/glycobiology" method="post"> <a href="/pathways/glycobiology" data-form="pathways_glycobiology_pathways" class="pathway_link"> <span class="icon-"> Glycobiology Pathways </span> </a> <input type="hidden" name="pw_parent" value="Glycobiology"> </form> </li> <li class="pathways-li "> <form id="pathways_immunology_pathways" action="/pathways/immunology" method="post"> <a href="/pathways/immunology" data-form="pathways_immunology_pathways" class="pathway_link"> <span class="icon-"> Immunology Pathways </span> </a> <input type="hidden" name="pw_parent" value="Immunology"> </form> </li> <li class="pathways-li "> <form id="pathways_neuroscience_pathways" action="/pathways/neuroscience" method="post"> <a href="/pathways/neuroscience" data-form="pathways_neuroscience_pathways" class="pathway_link"> <span class="icon-"> Neuroscience Pathways </span> </a> <input type="hidden" name="pw_parent" value="Neuroscience"> </form> </li> <li class="pathways-li "> <form id="pathways_proteases__other_enzymes_pathways" action="/pathways/proteases" method="post"> <a href="/pathways/proteases" data-form="pathways_proteases__other_enzymes_pathways" class="pathway_link"> <span class="icon-"> Proteases & Other Enzymes Pathways </span> </a> <input type="hidden" name="pw_parent" value="proteases"> </form> </li> <li class="pathways-li "> <form id="pathways_signal_transduction_pathways" action="/pathways/signal-transduction" method="post"> <a href="/pathways/signal-transduction" data-form="pathways_signal_transduction_pathways" class="pathway_link"> <span class="icon-"> Signal Transduction Pathways </span> </a> <input type="hidden" name="pw_parent" value="signal-transduction"> </form> </li> <li class="pathways-li active"> <form id="pathways_stem_cell_pathways" action="/pathways/stem-cells" method="post"> <a href="/pathways/stem-cells" data-form="pathways_stem_cell_pathways" class="pathway_link"> <span class="icon-"> Stem Cell Pathways </span> </a> <input type="hidden" name="pw_parent" value="stem-cells"> </form> <ul> <form id="pathways_embryonic_and_induced_pluripotent_stem_cell_differentiation_pathways__lineage-specific_markers" action="/pathways/embryonic-induced-pluripotent-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <li class=""> <a href="/pathways/embryonic-induced-pluripotent-stem-cell-differentiation-pathways-lineage-specific-markers" class="pathway_link" data-form="pathways_embryonic_and_induced_pluripotent_stem_cell_differentiation_pathways__lineage-specific_markers"> Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> <form id="pathways_hematopoietic_stem_cell_differentiation_pathways__lineage-specific_markers" action="/pathways/hematopoietic-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <li class=""> <a href="/pathways/hematopoietic-stem-cell-differentiation-pathways-lineage-specific-markers" class="pathway_link" data-form="pathways_hematopoietic_stem_cell_differentiation_pathways__lineage-specific_markers"> Hematopoietic Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> <form id="pathways_mesenchymal_stem_cell_differentiation_pathways__lineage-specific_markers" action="/pathways/mesenchymal-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <li class=""> <a href="/pathways/mesenchymal-stem-cell-differentiation-pathways-lineage-specific-markers" class="pathway_link" data-form="pathways_mesenchymal_stem_cell_differentiation_pathways__lineage-specific_markers"> Mesenchymal Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> <form id="pathways_neural_stem_cell_differentiation_pathways__lineage-specific_markers" action="/pathways/neural-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <li class=""> <a href="/pathways/neural-stem-cell-differentiation-pathways-lineage-specific-markers" class="pathway_link" data-form="pathways_neural_stem_cell_differentiation_pathways__lineage-specific_markers"> Neural Stem Cell Differentiation Pathways & Lineage-specific Markers </a> </li> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </ul> </li> <li class="pathways-li "> <form id="pathways_ubiquitin_related_modifiers__pathways" action="/pathways/ubiquitin-related-modifiers-and-pathways" method="post"> <a href="/pathways/ubiquitin-related-modifiers-and-pathways" data-form="pathways_ubiquitin_related_modifiers__pathways" class="pathway_link"> <span class="icon-"> Ubiquitin, Related Modifiers, & Pathways </span> </a> <input type="hidden" name="pw_parent" value="ubiquitin-related-modifiers-and-pathways"> </form> </li> </ul> </div> </div> </div> </div> </div> <div class="pw_right col-xs-12 col-sm-8 col-md-9"> <div class="search_mobile_buttons"> <div class="pw_menu_toggle btn btn-tertiary">Show Categories</div> </div> <div class="pw_header"> <h1>Stem Cell Pathways</h1> <div class="pathway_description"> <p><p>Stem cells are characterized by the ability to self-renew, or divide without senescing, and to differentiate into specialized somatic cells. Multiple stem cell subtypes have been identified, including embryonic, induced pluripotent, and adult stem cells. Embryonic stem cells are pluripotent and can differentiate into all cell types of the mature organism. In contrast, adult (somatic) stem cells, including hematopoietic, muscle, cardiac, neural, and mesenchymal stem cells, generally have more limited potency, and their differentiated derivatives are thought to primarily populate the tissue of residence. The illustrations found in this section feature the processes by which different types of stem cells differentiate into downstream lineages and highlight markers that can be utilized to identify them.</p> </p> </div> </div> <div class="pw_categories"> <h2>Interactive Pathways by Category</h2> <div class="row"> <div class="col-xs-12"> <div class="pw_categories"> <div class="row PathwayViewCon"> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_embryonic_and_induced_pluripotent_stem_cell_differentiation_pathways___lineage_specific_markers" action="/pathways/embryonic-induced-pluripotent-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <a href="/pathways/embryonic-induced-pluripotent-stem-cell-differentiation-pathways-lineage-specific-markers" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/embryonic-induced-pluripotent-stem-cells.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_embryonic_and_induced_pluripotent_stem_cell_differentiation_pathways___lineage_specific_markers"> <h2 class="pw_category_title">Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways & Lineage-specific Markers</h2> </a> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_hematopoietic_stem_cell_differentiation_pathways___lineage_specific_markers" action="/pathways/hematopoietic-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <a href="/pathways/hematopoietic-stem-cell-differentiation-pathways-lineage-specific-markers" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/hematopoietic-stem-cells.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_hematopoietic_stem_cell_differentiation_pathways___lineage_specific_markers"> <h2 class="pw_category_title">Hematopoietic Stem Cell Differentiation Pathways & Lineage-specific Markers</h2> </a> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_mesenchymal_stem_cell_differentiation_pathways___lineage_specific_markers" action="/pathways/mesenchymal-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <a href="/pathways/mesenchymal-stem-cell-differentiation-pathways-lineage-specific-markers" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/mesenchymal-stem-cells.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_mesenchymal_stem_cell_differentiation_pathways___lineage_specific_markers"> <h2 class="pw_category_title">Mesenchymal Stem Cell Differentiation Pathways & Lineage-specific Markers</h2> </a> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_neural_stem_cell_differentiation_pathways___lineage_specific_markers" action="/pathways/neural-stem-cell-differentiation-pathways-lineage-specific-markers" method="post"> <a href="/pathways/neural-stem-cell-differentiation-pathways-lineage-specific-markers" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/neural-stem-cells.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_neural_stem_cell_differentiation_pathways___lineage_specific_markers"> <h2 class="pw_category_title">Neural Stem Cell Differentiation Pathways & Lineage-specific Markers</h2> </a> <input type="hidden" name="pw_parent" value="stem-cells"> </form> </div> </div> </div> </div> </div> </div> </div> </div> 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