CINXE.COM

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class="burr-flipped-container burr-flipped-content-container clearfix"> <div class="burr-flipped-content burr-flipped-content-region panel-panel"> <div class="burr-flipped-content-inner burr-flipped-content-region-inner panel-panel-inner"> <div class="panel-pane pane-views-panes pane-news-page-panel-pane-2" > <div class="pane-content"> <div class="view view-news-page view-id-news_page view-display-id-panel_pane_2 view-dom-id-ae443185f8265ac6958fdcd7e2ee8820"> <div class="view-content"> <div class="submitted"> <div> <div class="views-field-created views-field">By Levi Gadye / Fri May 11, 2018</div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-node-content" > <div class="pane-content"> <div id="node-14206" class="node node-openacademy-news clearfix" about="/news/2018/05/research-outlines-challenges-adoption-new-genetic-tests" typeof="sioc:Item foaf:Document"> <span property="dc:title" content="" class="rdf-meta element-hidden"></span> <div class="content"> <div class="field field-name-field-featured-image field-type-image field-label-hidden"><div class="field-items"><div class="field-item even"><div id="file-39131" class="file file-image file-image-jpeg file-entity-third file-entity-element-container"> <div class="content"> <picture >  <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/featured/rs10528_20140121_1_0120.jpg?itok=J82Q4qxC&timestamp=1537290273 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/rs10528_20140121_1_0120.jpg?itok=WMse0X98&timestamp=1537290273 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/featured/rs10528_20140121_1_0120.jpg?itok=qrQ-Yqsi&timestamp=1537290273 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/featured/rs10528_20140121_1_0120.jpg?itok=tZrF6wyQ&timestamp=1537290273 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/rs10528_20140121_1_0120.jpg?itok=WMse0X98&timestamp=1537290273 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_1_5x/public/featured/rs10528_20140121_1_0120.jpg?itok=nOUTHOhP&timestamp=1537290273 3x" media="(min-width: 656px) and (max-width: 1024px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_quarter/public/featured/rs10528_20140121_1_0120.jpg?itok=moepL5JR&timestamp=1537290273 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/featured/rs10528_20140121_1_0120.jpg?itok=tZrF6wyQ&timestamp=1537290273 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/rs10528_20140121_1_0120.jpg?itok=WMse0X98&timestamp=1537290273 3x" media="(min-width: 481px) and (max-width: 655px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_half/public/featured/rs10528_20140121_1_0120.jpg?itok=tZrF6wyQ&timestamp=1537290273 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/rs10528_20140121_1_0120.jpg?itok=WMse0X98&timestamp=1537290273 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_1_5x/public/featured/rs10528_20140121_1_0120.jpg?itok=nOUTHOhP&timestamp=1537290273 3x" media="(min-width: 431px) and (max-width: 480px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/featured/rs10528_20140121_1_0120.jpg?itok=J82Q4qxC&timestamp=1537290273 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_three_quarters/public/featured/rs10528_20140121_1_0120.jpg?itok=WMse0X98&timestamp=1537290273 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_full/public/featured/rs10528_20140121_1_0120.jpg?itok=qrQ-Yqsi&timestamp=1537290273 3x" media="(min-width: 0px) and (max-width: 430px)" />  <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_third/public/featured/rs10528_20140121_1_0120.jpg?itok=J82Q4qxC&timestamp=1537290273" alt="Phillips" title="" /> </picture> <div class="field field-name-field-image-credit-term field-type-taxonomy-term-reference field-label-hidden"> <div class="field-items"> <div class="field-item even"><a href="https://elisabeth-fall.squarespace.com/" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Elisabeth Fall</a></div> </div> </div> <div class="field field-name-field-image-caption field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><p>Kathryn Phillips, PhD</p></div></div></div> </div> </div> </div></div></div><div class="field field-name-body field-type-text-with-summary field-label-hidden"><div class="field-items"><div class="field-item even" property="content:encoded"><p>Every day, on average, ten new genetic tests become commercially available to help doctors and patients make more informed decisions about health care. Yet few doctors know how to navigate the tens of thousands of tests that populate the genetic testing marketplace, which prevents patients from benefiting from them, according to <a href="/kathryn-phillips">Kathryn Phillips, PhD</a>.</p> <p>Phillips, a faculty member in the UCSF School of Pharmacy’s <a href="https://clinicalpharmacy.ucsf.edu/">Department of Clinical Pharmacy</a> and the founding director of the <a href="https://pharm.ucsf.edu/transpers">UCSF Center for Translational and Policy Research on Personalized Medicine</a> (TRANSPERS), has spent over two decades analyzing how advances in genetic testing are approved, adopted, and paid for. Until recently, though, no one had assessed, in its entirety, the broad array of genetic tests that doctors must now choose from if they want to provide personalized care to their patients.</p> <p>“If I were a provider trying to figure out what to order, that's where this is in some way the Wild West, because we have so many tests out there,” Phillips told the Washington Post in a recent article (<a href="https://www.washingtonpost.com/news/wonk/wp/2018/05/07/medicines-wild-west-10-new-genetic-tests-enter-the-market-each-day/?noredirect=on&utm_term=.fde083c2494a">Medicine’s Wild West: 10 new genetic tests enter the market each day</a>). “Trying to sort out what to use, when, and how much to pay for a test is pretty complicated.”</p> <p>To get a handle on the scope of this problem, Phillips and her colleagues looked at 75,000 currently available genetic tests, which encompass 10,000 genes and dozens of various health conditions and diseases. The study, published recently in Health Affairs (<a href="https://pubmed.ncbi.nlm.nih.gov/29733704/">Genetic Test Availability And Spending: Where Are We Now? Where Are We Going?</a>), cataloged the number and types of genetic tests available to doctors, and then investigated insurance expenditures on these tests.</p> <p>The researchers found that insurers spend the most on genetic tests for prenatal conditions and hereditary cancer genes, followed by all other types, such as tests that can help doctors choose the most effective drugs for particular patients.</p> <p>As some of Phillips’ other recent publications have demonstrated over the last few months, simple availability of a genetic test isn’t always enough to spur its adoption or use in the health care system. For example, the Centers for Medicare and Medicaid Services recently committed Medicare to covering certain types of FDA-approved genetic tests for advanced cancer patients—but there’s no guarantee that private insurers will follow suit, nor that other types of genetic tests will similarly be covered in the future.</p> <p>And even if insurers do decide to cover genetic tests, doctors must learn which tests are appropriate for which medical situations, and then learn how to thoroughly inform patients of the costs and benefits of each.</p> <p>Phillips’ finding, that prenatal tests are now being widely used to help expectant parents make important health care decisions, clearly reflects this process. “[Prenatal testing] was one of the most rapidly adopted and covered tests,” Phillips told the Washington Post. “It got huge market acceptance, and insurers now cover it pretty routinely for high-risk women.”</p> <p>This landscape of genetic testing may currently be foreign to much of the modern health care system, but thanks to Phillips, advances in precision medicine are slowly but surely making their way from bench to bedside.</p> <h2>More</h2> <ul> <li> <p><a href="https://www.healthaffairs.org/doi/full/10.1377/hlthaff.2017.1624">Precision Medicine: From Science To Value</a> (Health Affairs)</p> </li> <li> <p><a href="https://www.science.org/doi/10.1126/science.aas9268">Insurance coverage for genomic tests</a> (Science)</p> </li> <li> <p><a href="https://jamanetwork.com/journals/jama/fullarticle/2678995">Evolving Payer Coverage Policies on Genomic Sequencing Tests</a> (JAMA)</p> </li> </ul></div></div></div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-news-page-panel-pane-3" > <h2 class="pane-title">Tags</h2> <div class="pane-content"> <div class="view view-news-page view-id-news_page view-display-id-panel_pane_3 view-dom-id-e6550d9884556e42350dec28f222ca9f"> <div class="view-content"> <div> <div class="views-field views-field-field-keywords-revision-id"> <span class="views-label views-label-field-keywords-revision-id">Keywords: </span> <div class="field-content"><a href="/topics-expertise/genetic-testing" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">genetic testing</a>, <a href="/topics-expertise/pharmacogenomics" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">pharmacogenomics</a>, <a href="/topics-expertise/prenatal-testing" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">prenatal testing</a>, <a href="/topics-expertise/transpers" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">TRANSPERS</a>, <a href="/topics-expertise/health-economics" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">health economics</a></div> </div> <div class="views-field views-field-field-categories-revision-id"> <span class="views-label views-label-field-categories-revision-id">Category: </span> <div class="field-content"><a href="/categories/research" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Research</a>, <a href="/categories/patient-care" typeof="skos:Concept" property="rdfs:label skos:prefLabel" datatype="">Patient Care</a></div> </div> <div class="views-field views-field-nothing"> <span class="views-label views-label-nothing">Sites: </span> <div class="field-content">School of Pharmacy, Department of Clinical Pharmacy, PharmD Degree Program</div> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-related-profiles-news-related-profiles-pane" > <h2 class="pane-title">Related profiles</h2> <div class="pane-content"> <div class="view view-related-profiles view-id-related_profiles view-display-id-news_related_profiles_pane columns-4 view-dom-id-8766085279f941b74a4655019fa6749d"> <div class="view-content"> <div class="relatedprofile"> <span class="views-field views-field-field-person-headshot-photo"> <span class="field-content"><a href="https://pharmacy.ucsf.edu/kathryn-phillips"><picture >  <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=1AgHohoy&timestamp=1716918574 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_third/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=AM_SG3IN&timestamp=1716918574 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=EIeemPSE&timestamp=1716918574 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=1AgHohoy&timestamp=1716918574 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=pvWsUXTu&timestamp=1716918574 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=EIeemPSE&timestamp=1716918574 3x" media="(min-width: 656px) and (max-width: 1024px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=1AgHohoy&timestamp=1716918574 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=pvWsUXTu&timestamp=1716918574 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=EIeemPSE&timestamp=1716918574 3x" media="(min-width: 481px) and (max-width: 655px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=1AgHohoy&timestamp=1716918574 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=pvWsUXTu&timestamp=1716918574 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=EIeemPSE&timestamp=1716918574 3x" media="(min-width: 431px) and (max-width: 480px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=1AgHohoy&timestamp=1716918574 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_third/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=AM_SG3IN&timestamp=1716918574 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=EIeemPSE&timestamp=1716918574 3x" media="(min-width: 0px) and (max-width: 430px)" />  <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_half/public/person/photo/kathryn_a._phillips_cropped_1x1.jpg?itok=EIeemPSE&timestamp=1716918574" alt="Phillips" title="" /> </picture></a></span> </span> <div class="views-field views-field-path"> <span class="field-content"><a href="https://pharmacy.ucsf.edu/kathryn-phillips">Kathryn Phillips</a></span> </div> </div> </div> </div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-fieldable-panels-pane pane-current-171 pane-bundle-text" > <div class="pane-content"> <div class="fieldable-panels-pane"> <div class="field field-name-field-basic-text-text field-type-text-long field-label-hidden"><div class="field-items"><div class="field-item even"><hr /><p class="fine-print"><strong>About the School</strong>: The UCSF School of Pharmacy aims to solve the most pressing health care problems and strives to ensure that each patient receives the safest, most effective treatments. Our discoveries seed the development of novel therapies, and our researchers consistently lead the nation in NIH funding. The School’s doctor of pharmacy (PharmD) degree program, with its unique emphasis on scientific thinking, prepares students to be critical thinkers and leaders in their field.</p></div></div></div></div> </div> </div> </div> </div> <div class="burr-flipped-sidebar burr-flipped-content-region panel-panel"> <div class="burr-flipped-sidebar-inner burr-flipped-content-region-inner panel-panel-inner"> <div class="region region-sidebar region-background-callout"><div class="panel-pane pane-block pane-apachesolr-search-mlt-002 pane-basic" > <h2 class="pane-title">Related news</h2> <div class="pane-content"> <div class="item-list"><ul><li class="first"><a href="/news/2013/03/phillips-leads-national-study-benefit-risk-emergent-whole-genome-sequencing">Phillips leads national study of benefit/risk in emergent whole genome sequencing</a></li> <li><a href="/news/2024/05/phillips-explores-policy-ethics-precision-medicine">Phillips explores policy, ethics, and precision medicine</a></li> <li><a href="/news/2018/04/phillips-discusses-insurance-coverage-genomic-testing">Phillips discusses insurance coverage for genomic testing</a></li> <li><a href="/news/2008/10/phillips-awarded-5-million-nci-grant-study-personalized-medicine">Phillips awarded $5 Million NCI grant to study personalized medicine</a></li> <li class="last"><a href="/news/2009/10/study-identifies-lack-information-about-her2-testing-practices">Study identifies lack of information about HER2 testing practices</a></li> </ul></div> </div> </div> <div class="panel-separator"></div><div class="panel-pane pane-views-panes pane-openacademy-news-news-listing" > <h2 class="pane-title">Recent news</h2> <div class="pane-content"> <div class="view view-openacademy-news view-id-openacademy_news view-display-id-news_listing view-dom-id-0f2ce5c156dee47f404d51d9fb4aa92a"> <div class="view-content"> <div class="views-row views-row-1 views-row-odd views-row-first clearfix"> <div class="views-field views-field-rendered"> <span 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srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 1025px)" /> <source srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 656px) and (max-width: 1024px)" /> <source 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srcset="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601 1x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_sixth/public/featured/oni-orisan_and_tamraz.jpg?itok=p2CJEN0c&timestamp=1731708601 2x, /sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_quarter/public/featured/oni-orisan_and_tamraz.jpg?itok=k971xPLk&timestamp=1731708601 3x" media="(min-width: 0px) and (max-width: 430px)" />  <img src="/sites/pharmacy.ucsf.edu/files/styles/pharmacy_square_thumbnail/public/featured/oni-orisan_and_tamraz.jpg?itok=BEd7STEu&timestamp=1731708601" alt="Oni-Orisan and Tamraz" title="" /> </picture></a></span> </div> <div class="views-field views-field-title"> <span class="field-content"><a href="/news/2024/11/oni-orisan-tamraz-awarded-stripe-double-helix-award-contributions-pharmacogenomics">Oni-Orisan and Tamraz Awarded STRIPE Double Helix Award for Contributions to Pharmacogenomics</a></span> </div> 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