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class="vector-pinnable-header-label">Sisukord</h2> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-toc.pin">vii külgpaanile</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-toc.unpin">peida</button> </div> <ul class="vector-toc-contents" id="mw-panel-toc-list"> <li id="toc-mw-content-text" class="vector-toc-list-item vector-toc-level-1"> <a href="#" class="vector-toc-link"> <div class="vector-toc-text">Algus</div> </a> </li> <li id="toc-Liigitus" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Liigitus"> <div class="vector-toc-text"> <span class="vector-toc-numb">1</span> <span>Liigitus</span> </div> </a> <button aria-controls="toc-Liigitus-sublist" class="cdx-button cdx-button--weight-quiet cdx-button--icon-only vector-toc-toggle"> <span class="vector-icon mw-ui-icon-wikimedia-expand"></span> <span>Lülita ümber alaosa "Liigitus"</span> </button> <ul id="toc-Liigitus-sublist" class="vector-toc-list"> <li id="toc-Lümfokiinid" class="vector-toc-list-item vector-toc-level-2"> <a class="vector-toc-link" href="#Lümfokiinid"> <div class="vector-toc-text"> <span class="vector-toc-numb">1.1</span> <span>Lümfokiinid</span> </div> </a> <ul id="toc-Lümfokiinid-sublist" class="vector-toc-list"> </ul> </li> </ul> </li> <li id="toc-Ravimite_toime" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Ravimite_toime"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Ravimite toime</span> </div> </a> <ul id="toc-Ravimite_toime-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Viited" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Viited"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Viited</span> </div> </a> <ul id="toc-Viited-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Välislingid" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Välislingid"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Välislingid</span> </div> </a> <ul id="toc-Välislingid-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Sisukord" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Lülita sisukord ümber" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Lülita sisukord ümber</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">T-abistajarakud</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Mine teises keeles artiklisse. Saadaval 33 keeles" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-33" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">33 keelt</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D8%AE%D9%84%D9%8A%D8%A9_%D8%AA%D9%8A_%D9%85%D8%B3%D8%A7%D8%B9%D8%AF%D8%A9" title="خلية تي مساعدة – araabia" lang="ar" hreflang="ar" data-title="خلية تي مساعدة" data-language-autonym="العربية" data-language-local-name="araabia" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-id mw-list-item"><a href="https://id.wikipedia.org/wiki/Sel_T_pembantu" title="Sel T pembantu – indoneesia" lang="id" hreflang="id" data-title="Sel T pembantu" data-language-autonym="Bahasa Indonesia" data-language-local-name="indoneesia" class="interlanguage-link-target"><span>Bahasa Indonesia</span></a></li><li class="interlanguage-link interwiki-ms mw-list-item"><a href="https://ms.wikipedia.org/wiki/Sel_T_penolong" title="Sel T penolong – malai" lang="ms" hreflang="ms" data-title="Sel T penolong" data-language-autonym="Bahasa Melayu" data-language-local-name="malai" class="interlanguage-link-target"><span>Bahasa Melayu</span></a></li><li class="interlanguage-link interwiki-bs mw-list-item"><a href="https://bs.wikipedia.org/wiki/T-pomo%C4%87na_%C4%87elija" title="T-pomoćna ćelija – bosnia" lang="bs" hreflang="bs" data-title="T-pomoćna ćelija" data-language-autonym="Bosanski" data-language-local-name="bosnia" class="interlanguage-link-target"><span>Bosanski</span></a></li><li class="interlanguage-link interwiki-ca mw-list-item"><a href="https://ca.wikipedia.org/wiki/Limf%C3%B2cit_T_col%C2%B7laborador" title="Limfòcit T col·laborador – katalaani" lang="ca" hreflang="ca" data-title="Limfòcit T col·laborador" data-language-autonym="Català" data-language-local-name="katalaani" class="interlanguage-link-target"><span>Català</span></a></li><li class="interlanguage-link interwiki-cs mw-list-item"><a href="https://cs.wikipedia.org/wiki/Pomocn%C3%BD_T_lymfocyt" title="Pomocný T lymfocyt – tšehhi" lang="cs" hreflang="cs" data-title="Pomocný T lymfocyt" data-language-autonym="Čeština" data-language-local-name="tšehhi" class="interlanguage-link-target"><span>Čeština</span></a></li><li class="interlanguage-link interwiki-da mw-list-item"><a href="https://da.wikipedia.org/wiki/T-hj%C3%A6lpecelle" title="T-hjælpecelle – taani" lang="da" hreflang="da" data-title="T-hjælpecelle" data-language-autonym="Dansk" data-language-local-name="taani" class="interlanguage-link-target"><span>Dansk</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/T-Helferzelle" title="T-Helferzelle – saksa" lang="de" hreflang="de" data-title="T-Helferzelle" data-language-autonym="Deutsch" data-language-local-name="saksa" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-dv mw-list-item"><a href="https://dv.wikipedia.org/wiki/%DE%80%DE%AC%DE%8D%DE%B0%DE%95%DE%A6%DE%83_%DE%93%DE%A9_%DE%90%DE%AC%DE%8D%DE%B0" title="ހެލްޕަރ ޓީ ސެލް – maldiivi" lang="dv" hreflang="dv" data-title="ހެލްޕަރ ޓީ ސެލް" data-language-autonym="ދިވެހިބަސް" data-language-local-name="maldiivi" class="interlanguage-link-target"><span>ދިވެހިބަސް</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/T_helper_cell" title="T helper cell – inglise" lang="en" hreflang="en" data-title="T helper cell" data-language-autonym="English" data-language-local-name="inglise" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-es mw-list-item"><a href="https://es.wikipedia.org/wiki/Linfocito_T_CD4%2B" title="Linfocito T CD4+ – hispaania" lang="es" hreflang="es" data-title="Linfocito T CD4+" data-language-autonym="Español" data-language-local-name="hispaania" class="interlanguage-link-target"><span>Español</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%84%D9%86%D9%81%D9%88%D8%B3%DB%8C%D8%AA_%D8%AA%DB%8C_%DA%A9%D9%85%DA%A9%E2%80%8C%DA%A9%D9%86%D9%86%D8%AF%D9%87" title="لنفوسیت تی کمک‌کننده – pärsia" lang="fa" hreflang="fa" data-title="لنفوسیت تی کمک‌کننده" data-language-autonym="فارسی" data-language-local-name="pärsia" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Lymphocyte_T_auxiliaire" title="Lymphocyte T auxiliaire – prantsuse" lang="fr" hreflang="fr" data-title="Lymphocyte T auxiliaire" data-language-autonym="Français" data-language-local-name="prantsuse" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-gl mw-list-item"><a href="https://gl.wikipedia.org/wiki/Linfocito_T_CD4%2B" title="Linfocito T CD4+ – galeegi" lang="gl" hreflang="gl" data-title="Linfocito T CD4+" data-language-autonym="Galego" data-language-local-name="galeegi" class="interlanguage-link-target"><span>Galego</span></a></li><li class="interlanguage-link interwiki-ko mw-list-item"><a href="https://ko.wikipedia.org/wiki/%EB%B3%B4%EC%A1%B0_T%EC%84%B8%ED%8F%AC" title="보조 T세포 – korea" lang="ko" hreflang="ko" data-title="보조 T세포" data-language-autonym="한국어" data-language-local-name="korea" class="interlanguage-link-target"><span>한국어</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Linfocita_T_helper" title="Linfocita T helper – itaalia" lang="it" hreflang="it" data-title="Linfocita T helper" data-language-autonym="Italiano" data-language-local-name="itaalia" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-he mw-list-item"><a href="https://he.wikipedia.org/wiki/%D7%AA%D7%90_T_%D7%9E%D7%A1%D7%99%D7%99%D7%A2" title="תא T מסייע – heebrea" lang="he" hreflang="he" data-title="תא T מסייע" data-language-autonym="עברית" data-language-local-name="heebrea" class="interlanguage-link-target"><span>עברית</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/T-helpercel" title="T-helpercel – hollandi" lang="nl" hreflang="nl" data-title="T-helpercel" data-language-autonym="Nederlands" data-language-local-name="hollandi" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-ja mw-list-item"><a href="https://ja.wikipedia.org/wiki/Th2%E7%B4%B0%E8%83%9E" title="Th2細胞 – jaapani" lang="ja" hreflang="ja" data-title="Th2細胞" data-language-autonym="日本語" data-language-local-name="jaapani" class="interlanguage-link-target"><span>日本語</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Limfocyty_Th" title="Limfocyty Th – poola" lang="pl" hreflang="pl" data-title="Limfocyty Th" data-language-autonym="Polski" data-language-local-name="poola" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Linf%C3%B3cito_T_auxiliar" title="Linfócito T auxiliar – portugali" lang="pt" hreflang="pt" data-title="Linfócito T auxiliar" data-language-autonym="Português" data-language-local-name="portugali" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Limfocit_T_helper" title="Limfocit T helper – rumeenia" lang="ro" hreflang="ro" data-title="Limfocit T helper" data-language-autonym="Română" data-language-local-name="rumeenia" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/T-%D1%85%D0%B5%D0%BB%D0%BF%D0%B5%D1%80%D1%8B" title="T-хелперы – vene" lang="ru" hreflang="ru" data-title="T-хелперы" data-language-autonym="Русский" data-language-local-name="vene" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/T_helper_cell" title="T helper cell – lihtsustatud inglise" lang="en-simple" hreflang="en-simple" data-title="T helper cell" data-language-autonym="Simple English" data-language-local-name="lihtsustatud inglise" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sl mw-list-item"><a href="https://sl.wikipedia.org/wiki/Celica_pomagalka" title="Celica pomagalka – sloveeni" lang="sl" hreflang="sl" data-title="Celica pomagalka" data-language-autonym="Slovenščina" data-language-local-name="sloveeni" class="interlanguage-link-target"><span>Slovenščina</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije – serbia" lang="sr" hreflang="sr" data-title="T pomoćne ćelije" data-language-autonym="Српски / srpski" data-language-local-name="serbia" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/T_pomo%C4%87ne_%C4%87elije" title="T pomoćne ćelije – serbia-horvaadi" lang="sh" hreflang="sh" data-title="T pomoćne ćelije" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbia-horvaadi" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/T-hj%C3%A4lparcell" title="T-hjälparcell – rootsi" lang="sv" hreflang="sv" data-title="T-hjälparcell" data-language-autonym="Svenska" data-language-local-name="rootsi" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-th mw-list-item"><a href="https://th.wikipedia.org/wiki/%E0%B9%80%E0%B8%8B%E0%B8%A5%E0%B8%A5%E0%B9%8C%E0%B8%97%E0%B8%B5%E0%B9%80%E0%B8%AE%E0%B8%A5%E0%B9%80%E0%B8%9B%E0%B8%AD%E0%B8%A3%E0%B9%8C" title="เซลล์ทีเฮลเปอร์ – tai" lang="th" hreflang="th" data-title="เซลล์ทีเฮลเปอร์" data-language-autonym="ไทย" data-language-local-name="tai" class="interlanguage-link-target"><span>ไทย</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/T%E1%BA%BF_b%C3%A0o_T_h%E1%BB%97_tr%E1%BB%A3" title="Tế bào T hỗ trợ – vietnami" lang="vi" hreflang="vi" data-title="Tế bào T hỗ trợ" data-language-autonym="Tiếng Việt" data-language-local-name="vietnami" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Yard%C4%B1mc%C4%B1_T_h%C3%BCcresi" title="Yardımcı T hücresi – türgi" lang="tr" hreflang="tr" data-title="Yardımcı T hücresi" data-language-autonym="Türkçe" data-language-local-name="türgi" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%A2-%D1%85%D0%B5%D0%BB%D0%BF%D0%B5%D1%80" title="Т-хелпер – ukraina" lang="uk" hreflang="uk" data-title="Т-хелпер" data-language-autonym="Українська" data-language-local-name="ukraina" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E8%BC%94%E5%8A%A9%E6%80%A7T%E7%B4%B0%E8%83%9E" title="輔助性T細胞 – hiina" lang="zh" hreflang="zh" data-title="輔助性T細胞" data-language-autonym="中文" data-language-local-name="hiina" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q632518#sitelinks-wikipedia" title="Muuda keelelinke" class="wbc-editpage">Muuda linke</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Nimeruumid"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul 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class="vector-menu-heading"> Teistes projektides </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:T_helper_cell" hreflang="en"><span>Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q632518" title="Link andmehoidla seonduva üksuse juurde [g]" accesskey="g"><span>Andmeüksus</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Lehekülje tööriistad"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Ilme"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Ilme</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">vii külgpaanile</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">peida</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">Allikas: Vikipeedia</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="et" dir="ltr"><p><b>T-abistajarakud</b> ehk <b>CD4-rakud</b> ehk <b>CD4-lümfotsüüdid</b> ehk <b>T4-lümfotsüüdid</b> ehk <b>T<sub>h</sub> rakud</b> ehk <b>T<sub>H</sub> rakud</b> ehk <b>T-helperrakud</b> on paljude <a href="/wiki/Selgroogsed" title="Selgroogsed">selgroogsete</a> <a href="/wiki/L%C3%BCmfis%C3%BCsteem" title="Lümfisüsteem">lümfisüsteemi</a> rakud. T-abistajarakud liigitatakse <a href="/wiki/T-l%C3%BCmfots%C3%BC%C3%BCdid" title="T-lümfotsüüdid">T-lümfotsüütide</a> hulka. Nende ülesandeks on <a href="/wiki/Omandatud_immuunsus" title="Omandatud immuunsus">omandatud immuunkaitse</a> aktivatsioon ja <a href="/wiki/Ts%C3%BCtokiin" class="mw-redirect" title="Tsütokiin">tsütokiinide</a> komplekteerimine ning vabastamine teiste immuunkaitses osalevate rakkude abistamiseks.<sup id="cite_ref-1" class="reference"><a href="#cite_note-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> </p><p>Diferentseerunud CD4-rakkude pinnal paiknevad <a href="/w/index.php?title=CD4-retseptor&action=edit&redlink=1" class="new" title="CD4-retseptor (pole veel kirjutatud)">CD4-retseptorid</a> ja neid nimetatakse <a href="/w/index.php?title=CD4%2B_T_rakud&action=edit&redlink=1" class="new" title="CD4+ T rakud (pole veel kirjutatud)">CD4<sup>+</sup> T rakkudeks</a>. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Liigitus">Liigitus</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T-abistajarakud&veaction=edit&section=1" title="Muuda alaosa "Liigitus"" class="mw-editsection-visualeditor"><span>muuda</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T-abistajarakud&action=edit&section=1" title="Muuda alaosa "Liigitus" lähteteksti"><span>muuda lähteteksti</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>T-abistajarakud liigitatakse kokkuleppeliselt: </p> <ul><li><a href="/w/index.php?title=T0-helperrakud&action=edit&redlink=1" class="new" title="T0-helperrakud (pole veel kirjutatud)">T<sub>h</sub>0 rakud</a> ehk üldpopulatsioon; need aktiveerivad olenevalt tsütokiinide toimest diferentseerumise kas: <ul><li><a href="/w/index.php?title=Th1_rakud&action=edit&redlink=1" class="new" title="Th1 rakud (pole veel kirjutatud)">T<sub>h</sub>1 rakkudeks</a><sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> (seostatakse enim <a href="/wiki/Ts%C3%BCtokiin" class="mw-redirect" title="Tsütokiin">tsütokiinide</a> IFN-γ, IL-2, TNFα komplekteerimisega)</li> <li><a href="/w/index.php?title=Th2_rakud&action=edit&redlink=1" class="new" title="Th2 rakud (pole veel kirjutatud)">T<sub>h</sub>2 rakkudeks</a> <sup id="cite_ref-3" class="reference"><a href="#cite_note-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> (seostatakse enim järgmiste tsütokiinide IL-2, IL-4, IL-6, IL-10, TNFβ komplekteerimisega aga ka IL-5,IL-9 IL-13 komplekteerimisega<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup>)</li> <li><a href="/w/index.php?title=Th3_rakud&action=edit&redlink=1" class="new" title="Th3 rakud (pole veel kirjutatud)">T<sub>h</sub>3 rakkudeks</a>, nende ülesanded on seni ebaselged, arvatakse, et nad inhibeerivad T<sub>h</sub>1- ja T<sub>h</sub>2-rakke ja on spetsialiseerunud limaskesta kaitsele;</li></ul></li> <li><a href="/w/index.php?title=T%C3%BC%C3%BCp_17-T-abistajarakud&action=edit&redlink=1" class="new" title="Tüüp 17-T-abistajarakud (pole veel kirjutatud)">Tüüp 17-T-abistajarakud</a> (TH17-lümfotsüüdid) (avastatud 2005) (seostatakse enim tsütokiinidega IL-17a, IL-17e; neid loetakse olulisteks <a href="/wiki/Autoimmuunhaigused" class="mw-redirect" title="Autoimmuunhaigused">autoimmuunhaiguste</a> väljakujunemisel ja <a href="/w/index.php?title=Epiteelirakk&action=edit&redlink=1" class="new" title="Epiteelirakk (pole veel kirjutatud)">epiteelirakkude</a> kaitsel).</li></ul> <p>Üksik T-abistajarakk ei ole võimeline kõiki tsütokiine eritama, samuti ei komplekteeri nad organismis täpselt eeltoodud tsütokiine. Kui abistajarakud paljunevad ja moodustavad kloone siis võidakse neid uuesti aktiveerida nii, et nad hakkavad komplekteerima teisi tsütokiine, nagu näiteks IFN-γ, IL-4, IL-5, IL-10 ja TNF. </p> <ul><li><ul><li><ul><li>Mõnikord liigitatakse T-abistajarakkude alatüüpide hulka ka CD4+ T rakkude alatüübi <a href="/w/index.php?title=TFH_rakud&action=edit&redlink=1" class="new" title="TFH rakud (pole veel kirjutatud)">T<sub>FH</sub> rakud</a> – nende ülesandeks on T-<i>helperitelt</i> signaali saades <a href="/wiki/B-l%C3%BCmfots%C3%BC%C3%BCt" class="mw-redirect" title="B-lümfotsüüt">B-lümfotsüütide</a> aktivatsioon, mis võimaldab neil diferentseeruda <a href="/w/index.php?title=Antikehi&action=edit&redlink=1" class="new" title="Antikehi (pole veel kirjutatud)">antikehi</a> tootvateks plasmarakkudeks.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup></li></ul></li></ul></li></ul> <div class="mw-heading mw-heading3"><h3 id="Lümfokiinid"><span id="L.C3.BCmfokiinid"></span>Lümfokiinid</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T-abistajarakud&veaction=edit&section=2" title="Muuda alaosa "Lümfokiinid"" class="mw-editsection-visualeditor"><span>muuda</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T-abistajarakud&action=edit&section=2" title="Muuda alaosa "Lümfokiinid" lähteteksti"><span>muuda lähteteksti</span></a><span class="mw-editsection-bracket">]</span></span></div> <dl><dd><span typeof="mw:File"><span><img src="//upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Next.svg/12px-Next.svg.png" decoding="async" width="12" height="12" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Next.svg/18px-Next.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/a/a3/Next.svg/24px-Next.svg.png 2x" data-file-width="160" data-file-height="160" /></span></span> <i>Pikemalt artiklis <a href="/wiki/L%C3%BCmfokiinid" title="Lümfokiinid">Lümfokiinid</a></i></dd></dl> <p>Tähtsaimad T-abistajarakkude komplekteeritavad ja eritatavad tsütokiinide rühma kuuluvad <a href="/wiki/L%C3%BCmfokiinid" title="Lümfokiinid">lümfokiinid</a> tänapäeval on<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup> <a href="/w/index.php?title=IL-2&action=edit&redlink=1" class="new" title="IL-2 (pole veel kirjutatud)">IL-2</a>, <a href="/w/index.php?title=IL-3&action=edit&redlink=1" class="new" title="IL-3 (pole veel kirjutatud)">IL-3</a>, <a href="/w/index.php?title=IL-4&action=edit&redlink=1" class="new" title="IL-4 (pole veel kirjutatud)">IL-4</a>, <a href="/w/index.php?title=IL-5&action=edit&redlink=1" class="new" title="IL-5 (pole veel kirjutatud)">IL-5</a>, <a href="/w/index.php?title=IL-6&action=edit&redlink=1" class="new" title="IL-6 (pole veel kirjutatud)">IL-6</a>, G-CSF – <a href="/w/index.php?title=Granulots%C3%BC%C3%BCtide_ja_makrofaagide_(monots%C3%BC%C3%BCtide)_kolooniat_stimuleeriv_faktor&action=edit&redlink=1" class="new" title="Granulotsüütide ja makrofaagide (monotsüütide) kolooniat stimuleeriv faktor (pole veel kirjutatud)">granulotsüütide ja makrofaagide (monotsüütide) kolooniat stimuleeriv faktor</a>, <a href="/w/index.php?title=Gammainterferoon&action=edit&redlink=1" class="new" title="Gammainterferoon (pole veel kirjutatud)">gammainterferoon</a>. </p> <div class="mw-heading mw-heading2"><h2 id="Ravimite_toime">Ravimite toime</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T-abistajarakud&veaction=edit&section=3" title="Muuda alaosa "Ravimite toime"" class="mw-editsection-visualeditor"><span>muuda</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T-abistajarakud&action=edit&section=3" title="Muuda alaosa "Ravimite toime" lähteteksti"><span>muuda lähteteksti</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Mitmed <a href="/wiki/Ravimid" class="mw-redirect" title="Ravimid">ravimid</a> (sh <a href="/w/index.php?title=Immunosupressandid&action=edit&redlink=1" class="new" title="Immunosupressandid (pole veel kirjutatud)">immunosupressandid</a> nagu <a href="/w/index.php?title=Kortikosteroidid&action=edit&redlink=1" class="new" title="Kortikosteroidid (pole veel kirjutatud)">kortikosteroidid</a>, <a href="/w/index.php?title=Ts%C3%BCtostaatikumid&action=edit&redlink=1" class="new" title="Tsütostaatikumid (pole veel kirjutatud)">tsütostaatikumid</a> jt) pidurdavad <a href="/wiki/L%C3%BCmfots%C3%BC%C3%BCt" title="Lümfotsüüt">lümfotsüütide</a> paljunemist ja langetavad ka T-abistajarakkude hulka.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup> </p><p>Ka osad <a href="/wiki/Antibiootikumid" title="Antibiootikumid">antibiootikumid</a>, nagu näiteks <a href="/w/index.php?title=Ts%C3%BCklosporiin_A&action=edit&redlink=1" class="new" title="Tsüklosporiin A (pole veel kirjutatud)">tsüklosporiin A</a>, langetavad T-abistajarakkude paljunemisvõimet ja diferentseerumist ning langetavad ka <a href="/w/index.php?title=IL-2&action=edit&redlink=1" class="new" title="IL-2 (pole veel kirjutatud)">IL-2</a> komplekteerimist ja väljastamist. </p> <div class="mw-heading mw-heading2"><h2 id="Viited">Viited</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T-abistajarakud&veaction=edit&section=4" title="Muuda alaosa "Viited"" class="mw-editsection-visualeditor"><span>muuda</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T-abistajarakud&action=edit&section=4" title="Muuda alaosa "Viited" lähteteksti"><span>muuda lähteteksti</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="reflist" style="list-style-type: decimal;"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-1"><span class="mw-cite-backlink"><a href="#cite_ref-1">↑</a></span> <span class="reference-text">"<a href="/wiki/Meditsiinis%C3%B5nastik" title="Meditsiinisõnastik">Meditsiinisõnastik</a>" 111:2004.</span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><a href="#cite_ref-2">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://flexikon.doccheck.com/de/TH1-Zelle">T<sub>h</sub>1 rakk</a>, Veebiversioon (vaadatud 26.02.2014) (<i>saksa keeles</i>)</span> </li> <li id="cite_note-3"><span class="mw-cite-backlink"><a href="#cite_ref-3">↑</a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://flexikon.doccheck.com/de/TH2-Zelle">T<sub>h</sub>2 rakk</a>, Veebiversioon (vaadatud 26.02.2014) (<i>saksa keeles</i>)</span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text"><a href="/w/index.php?title=Sirje_Velbri&action=edit&redlink=1" class="new" title="Sirje Velbri (pole veel kirjutatud)">Sirje Velbri</a>, "Immuunpuudulikkus diagnostika ja ravi, AS Medicina, lk 21, 2002, <a href="/wiki/Eri:Raamatuotsimine/9985829417" class="internal mw-magiclink-isbn">ISBN 9985 829 41 7</a></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"><a href="/wiki/Ain_Heinaru" title="Ain Heinaru">Ain Heinaru</a>, "Geneetika" õpik kõrgkoolile, Tartu Ülikooli Kirjastus, lk 726, 2012, <a href="/wiki/Eri:Raamatuotsimine/9789949321711" class="internal mw-magiclink-isbn">ISBN 978-9949-32-171-1</a></span> </li> <li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text">Christopher R. Chapple, William D. Steers,<a rel="nofollow" class="external text" href="http://books.google.ee/books?id=A9m8TkdCUqEC&pg=PA189&dq=Important+lymphokines+secreted+by+the+T+helper+cell+include&hl=et&sa=X&ei=w4YQU-GVK4bpywOu7IDQDQ&redir_esc=y#v=onepage&q=Important%20lymphokines%20secreted%20by%20the%20T%20helper%20cell%20include&f=false">Practical Urology: Essential Principles and Practice: Essential Principles</a>, Springer-Verlag, lk 189, 2011, Google'i raamat veebiversioon (vaadatud 28.02.2014) (<i>inglise keeles</i>)</span> </li> <li id="cite_note-7"><span class="mw-cite-backlink"><a href="#cite_ref-7">↑</a></span> <span class="reference-text"><a href="/w/index.php?title=Sirje_Velbri&action=edit&redlink=1" class="new" title="Sirje Velbri (pole veel kirjutatud)">Sirje Velbri</a>, "Immuunpuudulikkus diagnostika ja ravi, AS Medicina, lk 128, 2002, <a href="/wiki/Eri:Raamatuotsimine/9985829417" class="internal mw-magiclink-isbn">ISBN 9985 829 41 7</a></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Välislingid"><span id="V.C3.A4lislingid"></span>Välislingid</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=T-abistajarakud&veaction=edit&section=5" title="Muuda alaosa "Välislingid"" class="mw-editsection-visualeditor"><span>muuda</span></a><span class="mw-editsection-divider"> | </span><a href="/w/index.php?title=T-abistajarakud&action=edit&section=5" title="Muuda alaosa "Välislingid" lähteteksti"><span>muuda lähteteksti</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li>Jaanus Suurväli,<a rel="nofollow" class="external text" href="http://www.horisont.ee/node/1749">Suured sammud oma ja omandatud immuunsuse uurimisel</a>, Horisont 6/2011</li> <li>Walter Berghoff,<a rel="nofollow" class="external text" href="http://www.praxis-berghoff.de/dokumente/DifferenzierungTHelferzellen.pdf">Differenzierung von T-Helferzellen in Typ 1 und Typ 2 entsprechend deren funktioneller Eigenschaften</a>, Veebiversioon (vaadatud 26.02.2014)<small> (<i>saksa keeles</i>)</small></li> <li>B. Kyewski, Elisabeth Suri-Payer, <a rel="nofollow" class="external text" href="http://books.google.ee/books?id=HmAOHU0rmhAC&pg=PA168&dq=CD4-cells+in+animals&hl=et&sa=X&ei=p_ENU8SkIMWv4ATi4YCgBg&redir_esc=y#v=onepage&q=CD4-cells%20in%20animals&f=false">CD4+CD25+ Regulatory T Cells: Origin, Function and Therapeutic Potential</a>, Google'i raamatu veebiversioon (vaadatud 26.02.2014)<small> (<i>inglise keeles</i>)</small></li> <li>Renata Mazzucchelli, Julie A. Hixon, Rosanne Spolski, Xin Chen, Wen Qing Li, Veronica L. Hall, Jami Willette-Brown, <a rel="nofollow" class="external text" href="http://www.bloodjournal.org/content/bloodjournal/112/8/3283.full.pdf?sso-checked=true">Development of regulatory T cells requires IL-7R stimulation by IL-7 or TSLP</a>, BLOOD, 15. oktoober 2008, 112. väljaanne, number 8, veebiversioon (vaadatud 26.11.2014.a.)<small>(<i>inglise keeles</i>)</small></li> <li>Fridolin Groß, Gerhard Metznerb, Ulrich Behna, <a rel="nofollow" class="external text" href="http://arxiv.org/pdf/1003.1053.pdf">Mathematical Modelling of Allergy and Speciﬁc Immunotherapy:Th1-Th2-Treg Interactions</a>, 2010, Elsevier, veebiversioon (vaadatud 28.02.2014) <small>(<i>inglise keeles</i>)</small></li> <li>Y Chen, S K Chauhan, H Soo Lee, D R Saban ja R Dana, <a rel="nofollow" class="external text" href="http://www.nature.com/mi/journal/v7/n1/full/mi201320a.html">Chronic dry eye disease is principally mediated by effector memory Th17 cells</a>, Mucosal Immunology (2014) 7, 38–45; doi:10.1038/mi.2013.20; 10. aprill 2013</li></ul>    </div><noscript><img src="https://login.wikimedia.org/wiki/Special:CentralAutoLogin/start?type=1x1" alt="" width="1" height="1" style="border: none; position: absolute;"></noscript> <div class="printfooter" data-nosnippet="">Pärit leheküljelt "<a dir="ltr" href="https://et.wikipedia.org/w/index.php?title=T-abistajarakud&oldid=5378349">https://et.wikipedia.org/w/index.php?title=T-abistajarakud&oldid=5378349</a>"</div></div> <div id="catlinks" class="catlinks" data-mw="interface"><div id="mw-normal-catlinks" class="mw-normal-catlinks"><a href="/wiki/Eri:Kategooriad" title="Eri:Kategooriad">Kategooriad</a>: <ul><li><a href="/wiki/Kategooria:Histoloogia" title="Kategooria:Histoloogia">Histoloogia</a></li><li><a href="/wiki/Kategooria:Kliiniline_meditsiin" title="Kategooria:Kliiniline meditsiin">Kliiniline meditsiin</a></li><li><a href="/wiki/Kategooria:L%C3%BCmfis%C3%BCsteem" title="Kategooria:Lümfisüsteem">Lümfisüsteem</a></li><li><a href="/wiki/Kategooria:Molekulaarbioloogia" title="Kategooria:Molekulaarbioloogia">Molekulaarbioloogia</a></li><li><a href="/wiki/Kategooria:Veterinaaria" title="Kategooria:Veterinaaria">Veterinaaria</a></li></ul></div><div id="mw-hidden-catlinks" class="mw-hidden-catlinks mw-hidden-cats-hidden">Peidetud kategooria: <ul><li><a href="/wiki/Kategooria:ISBN-v%C3%B5lulingiga_lehek%C3%BCljed" title="Kategooria:ISBN-võlulingiga leheküljed">ISBN-võlulingiga leheküljed</a></li></ul></div></div> </div> </main> </div> <div class="mw-footer-container"> <footer id="footer" class="mw-footer" > <ul id="footer-info"> <li id="footer-info-lastmod"> Selle lehekülje viimane muutmine: 20:56, 4. juuli 2019.</li> <li id="footer-info-copyright">Tekst on kasutatav vastavalt Creative Commonsi litsentsile "<a rel="nofollow" class="external text" href="https://creativecommons.org/licenses/by-sa/4.0/deed.et">Autorile viitamine + jagamine samadel tingimustel</a>"; sellele võivad lisanduda täiendavad tingimused. 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