CINXE.COM

Representation of regulation in the Gene Ontology (biological process)

<!DOCTYPE html> <html> <!-- Google tag (gtag.js) --> <script async src="https://www.googletagmanager.com/gtag/js?id=G-JDGZQ3MNS1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-JDGZQ3MNS1'); </script> <head> <meta charset="utf-8"> <meta http-equiv="X-UA-Compatible" content="IE=edge"> <meta name="viewport" content="width=device-width, initial-scale=1"> <title>Representation of regulation in the Gene Ontology (biological process)</title> <meta name="description" content="The Gene Ontology (GO) project is a major bioinformatics initiative to develop a computational representation of our evolving knowledge of how genes encode biological functions at the molecular, cellular and tissue system levels. "> <link rel="stylesheet" href="/css/main.css"> <!-- font awesome --> <link rel="stylesheet" href="/css/fontawesome.min.css"> <link rel="stylesheet" href="/css/brands.min.css"> <link rel="stylesheet" href="/css/regular.min.css"> <link rel="stylesheet" href="/css/solid.min.css"> <link rel="shortcut icon" href="/favicon.ico?1"> <!-- Begin Jekyll SEO tag v2.6.1 --> <title>Representation of regulation in the Gene Ontology (biological process) | Gene Ontology Resource</title> <meta name="generator" content="Jekyll v3.4.3" /> <meta property="og:title" content="Representation of regulation in the Gene Ontology (biological process)" /> <meta property="og:locale" content="en_US" /> <meta name="description" content="We have created a standard template for the definition of classes for the regulation of a biological process. This includes the definitions for positive and negative regulation. The equivalence axiom templates are “GO:0065007 and ‘regulates’ some X” (regulation), “GO:0065007 and ‘negatively_regulates’ some X” (negative regulation), and “GO:0065007 and ‘positively_regulates’ some X” (positive regulation), where X is a biological process." /> <meta property="og:description" content="We have created a standard template for the definition of classes for the regulation of a biological process. This includes the definitions for positive and negative regulation. The equivalence axiom templates are “GO:0065007 and ‘regulates’ some X” (regulation), “GO:0065007 and ‘negatively_regulates’ some X” (negative regulation), and “GO:0065007 and ‘positively_regulates’ some X” (positive regulation), where X is a biological process." /> <link rel="canonical" href="http://geneontology.org/GO_REF/0000058.html" /> <meta property="og:url" content="http://geneontology.org/GO_REF/0000058.html" /> <meta property="og:site_name" content="Gene Ontology Resource" /> <script type="application/ld+json"> {"description":"We have created a standard template for the definition of classes for the regulation of a biological process. This includes the definitions for positive and negative regulation. The equivalence axiom templates are “GO:0065007 and ‘regulates’ some X” (regulation), “GO:0065007 and ‘negatively_regulates’ some X” (negative regulation), and “GO:0065007 and ‘positively_regulates’ some X” (positive regulation), where X is a biological process.","url":"http://geneontology.org/GO_REF/0000058.html","@type":"WebPage","headline":"Representation of regulation in the Gene Ontology (biological process)","@context":"https://schema.org"}</script> <!-- End Jekyll SEO tag --> <link rel="canonical" href="http://geneontology.org/GO_REF/0000058.html"> <link rel="alternate" type="application/rss+xml" title="Gene Ontology Resource" href="http://geneontology.org/feed.xml" /> </head> <body> <nav class="navbar navbar-default navbar-fixed-top go-navbar"> <div class="container navbar-container" style="width: 100%;"> <div class="navbar-header"> <button type="button" class="navbar-toggle collapsed" data-toggle="collapse" data-target="#navbar" aria-expanded="false" aria-controls="navbar"> <span class="sr-only">Toggle navigation</span> <span class="icon-bar"></span> <span class="icon-bar"></span> <span class="icon-bar"></span> </button> <a class="navbar-brand go-link" href="/" style="margin-right: 20px;"> <span> <img src="/assets/go-logo.large.png"> </span> </a> </div> <div id="navbar" class="collapse navbar-collapse"> <ul class="nav navbar-nav"> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle link-extended u-letter-spacing-xxsmall" href="#" id="navbarDropdownMenuLink" role="button" data-toggle="dropdown" aria-haspopup="true" style="padding: 8px 3px;" aria-expanded="false">About</a> <div class="dropdown-menu" aria-labelledby="navbarDropdownMenuLink" style="width:248px; margin-bottom: 0px; padding: 0px; transform:translateY(-3px)"> <a href="/docs/introduction-to-go" class="dropdown-menu__item__link">About the GO</a><a href="/docs/whoweare/" class="dropdown-menu__item__link">Who we are</a><a href="/docs/collaborations/" class="dropdown-menu__item__link">Collaborations</a><a href="/docs/annotation-contributors/" class="dropdown-menu__item__link">Annotation contributors</a><a href="/docs/literature/" class="dropdown-menu__item__link">Scientific literature</a><a href="/docs/go-citation-policy/" class="dropdown-menu__item__link">GO citation policy and license</a> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle link-extended u-letter-spacing-xxsmall" href="#" id="navbarDropdownMenuLink" role="button" data-toggle="dropdown" aria-haspopup="true" style="padding: 8px 3px;" aria-expanded="false">Ontology</a> <div class="dropdown-menu" aria-labelledby="navbarDropdownMenuLink" style="width:248px; margin-bottom: 0px; padding: 0px; transform:translateY(-3px)"> <a href="/docs/ontology-documentation/" class="dropdown-menu__item__link">Gene Ontology overview</a><a href="/docs/download-mappings/" class="dropdown-menu__item__link">Cross-references of external classification systems to GO</a><a href="/docs/go-subset-guide/" class="dropdown-menu__item__link">Guide to GO subsets</a><a href="/docs/contributing-to-go-terms/" class="dropdown-menu__item__link">Contributing to the ontology</a> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle link-extended u-letter-spacing-xxsmall" href="#" id="navbarDropdownMenuLink" role="button" data-toggle="dropdown" aria-haspopup="true" style="padding: 8px 3px;" aria-expanded="false">Annotations</a> <div class="dropdown-menu" aria-labelledby="navbarDropdownMenuLink" style="width:248px; margin-bottom: 0px; padding: 0px; transform:translateY(-3px)"> <a href="/docs/go-annotations/" class="dropdown-menu__item__link">Introduction to GO annotations</a><a href="/docs/guide-go-evidence-codes/" class="dropdown-menu__item__link">Guide to GO evidence codes</a><a href="/docs/contributing-to-go/" class="dropdown-menu__item__link">Contributing GO annotations</a><a href="/docs/go-annotation-file-gaf-format-2.2/" class="dropdown-menu__item__link">GO Annotation File (GAF) format</a> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle link-extended u-letter-spacing-xxsmall" href="#" id="navbarDropdownMenuLink" role="button" data-toggle="dropdown" aria-haspopup="true" style="padding: 8px 3px;" aria-expanded="false">Downloads</a> <div class="dropdown-menu" aria-labelledby="navbarDropdownMenuLink" style="width:248px; margin-bottom: 0px; padding: 0px; transform:translateY(-3px)"> <a href="/docs/download-ontology/" class="dropdown-menu__item__link">Download ontology</a><a href="/docs/download-go-annotations/" class="dropdown-menu__item__link">Download annotations</a><a href="/docs/download-go-cams/" class="dropdown-menu__item__link">Download GO-CAMs</a> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle u-letter-spacing-xsmall" href="#" id="navbarDropdownMenuLink" role="button" data-toggle="dropdown" aria-haspopup="true" style="padding: 8px 3px;" aria-expanded="false"> Help </a> <div class="dropdown-menu" aria-labelledby="navbarDropdownMenuLink" style="width: 280px; margin-bottom: 0px;"> <a href="/search.html" title="Search GO Documentation" class="dropdown-menu__item__link"> <i class="fa-solid fa-search"></i> &nbsp; Search Documentation</a> <a href=" /docs/faq/ " class="dropdown-menu__item__link"> <i class="fa-solid fa-question" style="margin-right: 4px; margin-left: 2px;"></i> &nbsp; Frequently Asked Questions</a> <a href=" /docs/go-archives/ " class="dropdown-menu__item__link"> <i class="fa-solid fa-archive" style="margin-right: 4px; margin-left: 2px;"></i> &nbsp; GO Archives & Deprecated Products/Formats</a> <a href=" /docs/go-citation-policy/ " class="dropdown-menu__item__link"> <i class="fa-solid fa-pencil" style="margin-right: 4px; margin-left: 2px;"></i> &nbsp; Citation Policy & Terms</a> <a href="https://help.geneontology.org" target="blank" title="Contact the GO helpdesk" class="dropdown-menu__item__link"> <i class="fa-regular fa-comments"></i> &nbsp; Contact Us</a> </div> </li> </ul> <!-- SOCIAL LINKS --> <div class="navbar-right"> <ul class="nav navbar-nav"> <li> <a rel="me" href="https://bsky.app/profile/geneontology.bsky.social" target="blank" style="padding: 8px 3px; font-size: 15px;"> <i class="fa-brands fa-bluesky" aria-hidden="true"></i> </a> </li> <li> <a href="https://www.facebook.com/pages/Gene-Ontology/305908656519" target="blank" style="padding: 8px 3px; font-size: 15px;"> <i class="fa-brands fa-facebook-f" aria-hidden="true"></i> </a> </li> <li> <a href="https://github.com/geneontology" target="blank" style="padding: 8px 3px; font-size: 15px;"> <i class="fa-brands fa-github" aria-hidden="true"></i> </a> </li> <li style="margin-right: 5px"> <a href="https://genomic.social/@go" target="blank" style="padding: 8px 3px; font-size: 15px;"> <i class="fa-brands fa-mastodon" aria-hidden="true"></i> </a> </li> </ul> <a href="https://www.alliancegenome.org" target="blank" alt="Alliance of Genome Resources" > <img src="/assets/ALLIANCE-logo-nobackground_foundingmember.png" alt="Alliance of Genome Resources" style="height: 60px; margin-right: 10px;"/> </a> </div> </div> </div> </nav> <div class="page-content"> <div class="wrapper"> <div class="container"> <div class="u-margin-bottom-medium"> <a href="/gorefs"> <i class="fa-solid fa-chevron-left" aria-hidden="true"></i> All GO REFs </a> </div> <div> <span class="label label-primary">GO_REF:0000058</span> </div> <h2>Representation of regulation in the Gene Ontology (biological process)</h2> <p>GO ontology editors; 2013</p> <p><p>We have created a standard template for the definition of classes for the regulation of a biological process. This includes the definitions for positive and negative regulation. The equivalence axiom templates are “GO:0065007 and ‘regulates’ some X” (regulation), “GO:0065007 and ‘negatively_regulates’ some X” (negative regulation), and “GO:0065007 and ‘positively_regulates’ some X” (positive regulation), where X is a biological process.</p> </p> </div> </div> </div> <footer class="footer"> <hr style="margin:8px; padding:0px"> <div > <div class="col-sm-5" style="padding-left: 45px; text-align: left;"> <div class="footer__navigation"> <ul class="footer__list" style="padding-left: 0px;"> <li class="footer__item"> <a href="/" class="footer__link link-extended" style="color: white !important;">Home</a> </li> <li class="footer__item"> <a href="https://help.geneontology.org" class="footer__link link-extended" style="color: white !important;" target="blank">Contact us</a> </li> <li class="footer__item"> <a href="/docs/go-citation-policy/" class="footer__link link-extended" style="color: white !important;">Citation and Terms of Use</a> </li> </ul> </div> </div> <div class="col-sm-2" style="padding-left: 45px; padding-right: 45px; text-align: center;"> <div class="footer__logo-list"> <a href="https://globalbiodata.org/scientific-activities/global-core-biodata-resources" target="blank" alt="Global Core Biodata Resource" > <img src="/assets/GCBR-Logo-White.png" alt="Global Core Biodata Resource" style="height: 60px;"/> </a> </div> </div> <div class="col-sm-5" style="padding-left: 0px; padding-right: 35px; text-align: right;"> <p class="footer__copyright"> <small class="footer__text"> Copyright © 1999-2025 Member of the <a href="https://obofoundry.org/" class="footer__link" rel="external" title="Open Biological Ontologies" target="blank">Open Biological Ontologies Foundry</a> The GO Consortium is funded by the National Human Genome Research Institute (US National Institutes of Health), grant number <a href="https://reporter.nih.gov/search/BqfmFvQGv0CWrEFOkzTp-w/project-details/10348001" class="footer__link" rel="external" title="HG012212"target="blank">HG012212</a>, with co-funding by NIGMS. </small> </p> </div> </div> </footer> <script> var baseurl = '' </script> <script src="//code.jquery.com/jquery-1.10.2.min.js"></script> <script src="/js/bootstrap.min.js "></script> <script src="/js/typeahead.bundle.min.js "></script> <script src="/js/main.js "></script> </body> </html>

Pages: 1 2 3 4 5 6 7 8 9 10