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Tested in Western Blot (WB), Immunocytochemistry (ICC/IF), Immunohistochemistry (Paraffin) (IHC (P)) and Flow Cytometry (Flow) applications. This antibody reacts with Human, Mouse, Rat samples. 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as a Method * define function as object methods * @type {Object} */ window.digitalData = { user: {}, page: {}, merchandising: {}, getQueryParam : function (param) { var index, key, value, hash; var hashes = window.location.href.slice(window.location.href.indexOf('?') + 1).split('&'); for (index = 0; index < hashes.length; index++) { hash = hashes[index].split('='); key = hash[0]; value = hash[1]; if (key.toUpperCase() === param.toUpperCase()) return value; } return ''; }, getValOnce: function (value, cookieName, expiry, timeUnit) { var currentDate = new Date; var currentCookieValue; // timeUnit of 'm' is minutes represented in milliseconds // thus 86400000 = 24 hours = 1 day var interval = timeUnit == 'm' ? 60000 : 86400000; cookieName = cookieName ? cookieName : 'digitaldata_gvo'; value = value ? value : ''; expiry = expiry ? expiry : 0; currentCookieValue = this.getCookie(cookieName); if (value) { currentDate.setTime(currentDate.getTime() + expiry * interval); this.setCookie(cookieName, value, expiry == 0 ? 0 : currentDate); } return value == currentCookieValue ? '' : value; }, getCookie: function (key) { var result = ""; var cookies = document.cookie ? document.cookie.split('; ') : []; for (var i = 0; i < cookies.length; i++) { var parts = cookies[i].split('='); var name = decodeURIComponent(parts.shift()); var cookie = parts ? parts.join('=') : []; // Prevent storing or parsing of a cookie that we couldn't decode. if (cookie && key === name) { // removes surrounding quotes if (cookie.indexOf('"') === 0) { // This is a quoted cookie as according to RFC2068, unescape... cookie = cookie.slice(1, -1).replace(/\\"/g, '"').replace(/\\\\/g, '\\'); } // parse utf8 characters try { cookie = decodeURIComponent(cookie); } catch (e) {} result = cookie; // we found it, don't bother looking at other cookies break; } } return result; }, setCookie : function(name, value, numDays){ if ( !numDays ) numDays = 31; var expires = new Date(); expires.setTime(expires.getTime() + (1000 * 60 * 60 * 24 * numDays)); document.cookie = name+ '=' + escape(value) + '; path=/; expires=' + expires.toGMTString() + '; domain=.' + this.getMasterDomain() + ';'; }, /** * get the master domain based on business rules */ getMasterDomain : function () { // default the master domain var masterDomain = 'thermofisher.com'; // check for alternate domain portion of URL var regexMatch = document.location.hostname.match(/\.(thermofisher)\.(cn)/i); if (regexMatch !== null) { masterDomain = regexMatch[1] + '.' + regexMatch[2]; } return masterDomain; }, /** * Check if init has been initiated once * @type {Boolean} */ initted: false, /** * @return {Array} method returns an array of a given object's key properties */ init: function () { this.page.country = this.getCookie("CK_ISO_CODE") || 'us'; this.page.language = this.getCookie('CK_LANG_CODE') || 'en'; this.page.siteName = 'thermo'; //hard coded this.initMerchandisingData(); this.initUserData(); this.displayDigitalData(); this.formSubmitEvent(); }, //specific function to set type of the page // need specific function to keep page type separate from other page attributes setPageType: function (type) { this.setPageAttribute('type', type); }, // generic function to set page attributes setPageAttribute: function (key, value) { this.page[key] = value; }, // display digitalData object displayDigitalData: function () { }, // specific function to add an object to digitalData addDigitDataObject: function (key, object) { this[key] = object; }, addChildObjectAttribute: function(child, key, value){ this[child][key] = value; }, initUserData: function(){ var gigyaCookie = this.getCookie("identity_uid"); this.user.gigyaId = ""; this.user.loginStatus = "anonymous"; if( gigyaCookie != ""){ this.user.gigyaId = gigyaCookie; this.user.loginStatus = "logged in"; } }, /** * Check if init has been initiated once * @type {Boolean} */ merchandisingDataInitted: false, initMerchandisingData: function () { // read cid and icid value from session cookie this.merchandising.icid = this.getCookie('s_ev21_tc'); this.merchandising.cid = this.getCookie('s_cmp_tc'); // EMID value this.merchandising.emid = this.getQueryParam("emid"); // referrer by domain if (typeof document.referrer !== 'undefined' && document.referrer.length > 0) { var masterDomain = this.getMasterDomain(); var refReg = document.referrer; var referrerDomain = refReg.match(/:\/\/([^/]+)\//); if (referrerDomain !== null && referrerDomain[1].indexOf(masterDomain) == -1) { this.merchandising.referrer = referrerDomain; } } document.addEventListener('registerMerchandisingData', function (event) { for (var key in event.detail) { console.log("Listener data copied", key, event.detail[key] ); digitalData.merchandising[key] = event.detail[key]; } // Map some analytics attributes to merchandising session attributes digitalData.merchandising.sessionId = digitalData.merchandising.analyticsVisitorID; digitalData.merchandising.s_vi_low = digitalData.merchandising.analyticsVisitorIDLow; digitalData.merchandising.s_vi_high = digitalData.merchandising.analyticsVisitorIDHigh; console.log("digitalData: Captured registerMerchandisingData event"); digitalData.merchandisingDataInitted = true; // Call emailCampaignRecord if the digitalDataAnalyticsListener object is loaded if (typeof digitalDataAnalyticsListener != "undefined") { console.log("digitalData: Calling email campaign record"); digitalDataAnalyticsListener.emailCampaignRecord(); } }); }, formSubmitEvent: function () { var formId = this.getQueryParam("form-submit-id"); if ((formId) && formId !== "" && formId !== null) { var eventDetail = { detail: { form: { id: formId } } }; var formSubmitEvent = new CustomEvent('formSubmit', eventDetail); console.log('form submit event started'); document.dispatchEvent(formSubmitEvent); console.log('form submit event fired', eventDetail); //flush grepToken from Session Storage sessionStorage.removeItem('grepTokenSO'); } }, modalVideoEvent: function (videoId) { if (((videoId) && videoId !== "" && videoId !== null)) { var eventDetail = { detail: { video: { playerId: videoId } } }; var modalVideoEvent = new CustomEvent('videoPlayerLoaded', eventDetail); document.dispatchEvent(modalVideoEvent); } }, customClickEvent: function (clickDetail) { if (((clickDetail) && clickDetail !== "" && clickDetail !== null)) { var eventDetail = { detail: { CustomLink: { linkName: clickDetail } } } var customClickEvent = new CustomEvent('customLinkClicks', eventDetail); document.dispatchEvent(customClickEvent); } } } })(); window.digitalData.init(); </script>  <script type="text/javascript"> window.performance && window.performance.mark && window.performance.mark("header_25"); </script> <script type="text/javascript"> var localizedStrings = { "ACCEPTANCE": "Acceptance of Terms of Use", "BTN_AGREE": "Agree", "BTN_DISAGREE": "Disagree", "PROCESSING_MESSAGE" :"processing ... please wait ...", "ADD_TO_CART_QUANTITY_ERROR":"You must provide a quantity to add an item to the cart", "ADD_TO_CART_VALID_QUANTITY_ERROR":"You must provide a valid quantity to add an item to the cart", "VIEW_CART" :"View cart & checkout", "VIEW_CONTACT_DETAIL" :"View Contact Details", "ADD_TO_CART_NOTIFICATION":"Add to Cart Notification", "UPDATE_CART" :"Update Cart", "PRINCIPAL_INVESTIGATOR":"Principal Investigator", "PRINCIPAL_INVESTIGATOR_TEAM_LEADER":"Principal Investigator or Team Leader", "PRINCIPAL_INVESTIGATOR_CHIEF":"Principal Investigator or Chief", "EMAIL_ERROR_1" :"Please Provide Collegues Email", "EMAIL_ERROR_2" :"Please enter a valid colleague email address", "EMAIL_ERROR_3" :"Please Provide Your Email", "EMAIL_ERROR_4" :"Please enter a valid email address", "ERROR_OCCURED_MESSAGE" :"The following errors occured", "NEXT" :"Next", "PREVIOUS" :"Prev", "IMAGE" :"Image", "SAVE_TO_LIST_ERROR_1" :"Please enter a list name.", "SAVE_TO_LIST_ERROR_2" :"Please enter a different list name that does not include the following: ?,/,\\,%,^,!", "MINICART_ERROR_1" :"Unable to connect to eCommerce system. 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Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented. </p> </div> </div> </div> </div> <div class="pdp-components"> <div id="pdp-components" ng-controller="pdpMainController as $ctrl">  <div block-ui="main" class="block-ui-main"></div> <div class="hero hero-loading-height" ng-class="{'is-loaded':$ctrl.isLoaded, 'with-banner': 'false' == 'true'}"> <div class="container"> <div class="hero-content"> <div class="brand-breadcrumb to-hide-on-mobile row"> <div class="large-span-12 medium-span-12 target_page_breadcrumbs"> <div class="breadcrumb breadcrumb-hide-restricted-only"> <ul class="breadcrumb breadcrumb-hide-restricted-only hero-breadcrumbs"> <li class="active"> <a href="/us/en/home/life-science/antibodies/primary-antibodies.html" target="_self"> Primary Antibodies </a> <span class="divider">&rsaquo;</span> </li> <li class="active"> <a href="/antibody/primary/target/ki-67" target="_self" class="targetLink"> Ki-67 Antibodies</a> </li> </ul> </div> </div> </div> <svg xmlns="http://www.w3.org/2000/svg" display="none"> <symbol id="close-drawer-icon" viewBox="0 0 22.74 22.74"> <line x1="1.67" y1="1.67" x2="21.33" y2="21.33" style="fill:none;stroke:#555759;stroke-linecap:square;stroke-width:2px"/> <line x1="21.07" y1="1.41" x2="1.41" y2="21.07" style="fill:none;stroke:#555759;stroke-linecap:square;stroke-width:2px"/> </symbol> <symbol id="info-icon" viewBox="0 0 32 32"> <path fill="#1e8ae7" d="M16 10.688c-1.152 0-2.048-0.896-2.048-2.048s0.896-2.048 2.048-2.048c1.152 0 2.048 0.896 2.048 2.048 0 1.088-0.96 2.048-2.048 2.048zM17.792 22.976c0 0.768-0.064 1.152-0.256 1.536-0.256 0.576-0.832 0.896-1.6 0.896-0.704 0-1.28-0.32-1.6-0.896-0.192-0.384-0.256-0.768-0.256-1.536v-8.256c0-0.768 0.064-1.152 0.256-1.536 0.256-0.576 0.832-0.896 1.6-0.896 0.704 0 1.28 0.32 1.6 0.896 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class="details-hero" ng-click="$ctrl.toggleImages('ADVANCED_VERIFICATION')"> <a class="link adv-verification-link animated-scroll" href="/sg/en/home/life-science/antibodies/invitrogen-antibody-validation.html"> <svg class="svg-icon advanced-verification-icon"> <use href="#icon-advanced-verification"></use> </svg> Advanced Verification </a> <p class="adv-verification-detail" onclick="window.THERMO_FISHER.pdp.inp.toggleImagesAdvVerificationSmLtr(event, this)"> This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated. </p> </div> <div class="details-hero"> <a class="link references-link animated-scroll " href="#references-component-id" onclick="window.THERMO_FISHER.pdp.inp.referencesHero(event, this)"> <svg class="svg-icon references-icon"> <use href="#icon-references"></use> </svg> 795 References </a> </div> <div class="details-hero"> <a class="btn hero-btn hero-view-other" href="/antibody/primary/target/ki-67"> View all (211) Ki-67 antibodies </a> </div> </div> <div class="links-ab to-show-links-in-sm"> <div class="container"> <div class="link-container"> <a class="link-antibody" href="/order/genome-database/dataSheetPdf?producttype=antibody&productsubtype=antibody_primary&productId=MA5-14520&version=Local" target="_blank" rel="nofollow"> <span> <svg class="svg-icon data-sheet-icon"> <use href="#icon-data-sheet"></use> </svg> </span> Datasheet </a> </div> <div class="link-container"> <a href="https://www.thermofisher.com/global/en/home/life-science/antibodies/antibodies-learning-center/antibody-protocols.html?icid=antibody-pdp-protocols" target="_blank" class="link-antibody"> <span> <svg class="svg-icon protocols-icon"> <use href="#icon-protocols"></use> </svg> </span> Protocols </a> </div> <div class="link-container"> <a href="/us/en/home/technical-resources/contact-us.MA514520.html?supportType=TS" class="link-antibody"> <span> <svg class="svg-icon tech-support-icon"> <use href="#icon-tech-support"></use> </svg> </span> 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was used in this experiment: Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) from Thermo Fisher Scientific, catalog # MA5-14520, RRID AB_10979488.</textarea> </div> <div class="modal-footer">  <button type="button" class="well-red btn btn-danger pull-left" data-dismiss="modal" onclick="copyToClipboard();" > Click to Copy </button>  </div> </div> </div> <script type="application/ld+json"> { "@context": "https://schema.org/", "@type": "BreadcrumbList", "itemListElement": [{ "@type": "ListItem", "position": 1, "name": "Home", "item":"https://www.thermofisher.com" },{ "@type": "ListItem", "position": 2, "name": "Antibodies", "item": "https://www.thermofisher.com/us/en/home/life-science/antibodies.html" },{ "@type": "ListItem", "position": 3, "name": "Ki-67", "item": "https://www.thermofisher.com/antibody/primary/target/ki-67" }] } </script> </div> <div class="links-ab to-hide-links-in-sm"> <div class="container"> <div class="link-container"> <a class="link-antibody" href="/order/genome-database/dataSheetPdf?producttype=antibody&productsubtype=antibody_primary&productId=MA5-14520&version=Local" target="_blank" rel="nofollow"> <span> <svg class="svg-icon data-sheet-icon"> <use href="#icon-data-sheet"></use> </svg> </span> Datasheet </a> </div> <div class="link-container"> <a href="https://www.thermofisher.com/global/en/home/life-science/antibodies/antibodies-learning-center/antibody-protocols.html?icid=antibody-pdp-protocols" target="_blank" class="link-antibody"> <span> <svg class="svg-icon protocols-icon"> <use href="#icon-protocols"></use> </svg> </span> Protocols </a> </div> <div class="link-container"> <a href="/us/en/home/technical-resources/contact-us.MA514520.html?supportType=TS" class="link-antibody"> <span> <svg class="svg-icon tech-support-icon"> <use href="#icon-tech-support"></use> </svg> </span> Tech Support </a> </div> </div> </div> <div id="image-gallery" class="scrollClass image-gallery-loading-height" ng-class="{'is-loaded':$ctrl.isLoaded}"> <div id="tabName" tab-name-value="changeTabValue"></div> <div id="originalProductLink" product-link-value="originalProductLinkValue"></div> <div class="gal-cntr container" tfs-media-gallery sku="'MA5-14520'" media-items="{'Antibody Testing Data':[{'sku':'MA5-14520','imageId':'647983','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki67-ICC-20191209134648.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki67-ICC-20191209134648.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA514520-Ki67-ICC-20191209134648.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA514520-Ki67-ICC-20191209134648.jpg?time\u003d20240507','sortOrder':'3','description':'Immunofluorescence analysis of Ki-67 was performed using 70% confluent log phase HeLa cells serum starved (SS) for 36 hours followed by serum release (SR) for 6 hours. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:250 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790) at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). F-actin (Panel c: red) was stained with Rhodamine Phalloidin (Product # R415, 1:300). Panel d represents the merged image showing nuclear localization. Panel e represents the serum starved cells with reduced signal. Panel f represents control cells with no primary antibody to assess background. The images were captured at 60X magnification.','shortDescription':'Immunofluorescence analysis of Ki-67 was performed using 70% confluent log phase HeLa cells serum starved (SS) for 36 hours followed by serum release (SR) for 6 hours. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:250 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) H... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'Ki-67 Antibody in Immunocytochemistry (ICC/IF)','title':'Ki-67 Antibody (MA5-14520) in ICC/IF','appAbv':'ICC/IF','appName':'Immunocytochemistry','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'MA514520-Ki67-ICC-20191209134648.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'1007873','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-ICCIF-1-20230731_142446.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-ICCIF-1-20230731_142446.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA5-14520-KI-67-ICCIF-1-20230731_142446.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA5-14520-KI-67-ICCIF-1-20230731_142446.jpg?time\u003d20240507','sortOrder':'4','description':'Knockout of Ki-67 was achieved by CRISPR-Cas9 genome editing using LentiArray™ Lentiviral sgRNA (Product # A32042, Assay ID CRISPR955684_LV) and LentiArray Cas9 Lentivirus (Product # A32064). Immunofluorescence analysis was performed on HeLa wild type cells (panel a,d), HeLa Cas9 control cells (panel b,e) and HeLa Ki-67 KO cells (panel c, f). Cells were fixed, permeabilized, and labeled with Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520, 1:500 dilution), followed by Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor™ Plus 488 (Product#A32790, 1:2000 dilution). Nuclei (blue) were stained using ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962), and Rhodamine Phalloidin (Product # R415, 1:300) was used for cytoskeletal F-actin (red) staining. Loss of signal (panel c,f) upon CRISPR mediated knockout (KO) confirms that antibody is specific to Ki-67 (green). The images were captured at 60X magnification.','shortDescription':'Knockout of Ki-67 was achieved by CRISPR-Cas9 genome editing using LentiArray™ Lentiviral sgRNA (Product # A32042, Assay ID CRISPR955684_LV) and LentiArray Cas9 Lentivirus (Product # A32064). Immunofluorescence analysis was performed on HeLa wild type cells (panel a,d), HeLa Cas9 control cells (panel b,e) and HeLa Ki-67 KO cells (panel c, f). Cells were fixed, permeabilized, and labeled with Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520, 1:500 dilution), followed by Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorb... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'Ki-67 Antibody in Immunocytochemistry (ICC/IF)','title':'Ki-67 Antibody (MA5-14520) in ICC/IF','appAbv':'ICC/IF','appName':'Immunocytochemistry','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'MA5-14520-KI-67-ICCIF-1-20230731_142446.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'987581','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-IHCP-1-20230519_140711.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-IHCP-1-20230519_140711.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA5-14520-KI-67-IHCP-1-20230519_140711.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA5-14520-KI-67-IHCP-1-20230519_140711.jpg?time\u003d20240507','sortOrder':'5','description':'Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Following antigen retrieval, the sections were blocked with 2% normal goat serum in 1X PBS for 45 minutes at room temperature and then probed with or without Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:100 dilution in 0.1% normal goat serum overnight at 4 degree Celsius in a humidified chamber. Detection was performed using Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at a dilution of 1:2000 in 0.1% normal goat serum for 45 minutes at room temperature. ReadyProbes™ Tissue Autofluorescence Quenching Kit (Product # R37630) was used to quench autofluorescence from the tissues. Nuclei were stained with DAPI (Product # D1306) and the sections were mounted using ProLong™ Glass Antifade Mountant (Product # P36984). The images were captured on EVOS™ M7000 Imaging System (Product # AMF7000) at 20X magnification and externally deconvoluted.','shortDescription':'Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 1... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))','title':'Ki-67 Antibody (MA5-14520) in IHC (P)','appAbv':'IHC (P)','appName':'Immunohistochemistry (Paraffin)','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'MA5-14520-KI-67-IHCP-1-20230519_140711.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'987582','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-IHCP-2-20230519_140711.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-IHCP-2-20230519_140711.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA5-14520-KI-67-IHCP-2-20230519_140711.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA5-14520-KI-67-IHCP-2-20230519_140711.jpg?time\u003d20240507','sortOrder':'6','description':'Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - Low pH (10X) (Product # 00-4955-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Following antigen retrieval, the sections were blocked with 2% normal goat serum in 1X PBS for 45 minutes at room temperature and then probed with or without Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:100 dilution in 0.1% normal goat serum overnight at 4 degree Celsius in a humidified chamber. Detection was performed using Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at a dilution of 1:2000 in 0.1% normal goat serum for 45 minutes at room temperature. ReadyProbes™ Tissue Autofluorescence Quenching Kit (Product # R37630) was used to quench autofluorescence from the tissues. Nuclei were stained with DAPI (Product # D1306) and the sections were mounted using ProLong™ Glass Antifade Mountant (Product # P36984). The images were captured on EVOS™ M7000 Imaging System (Product # AMF7000) at 20X magnification and externally deconvoluted.','shortDescription':'Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - Low pH (10X) (Product # 00-4955-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))','title':'Ki-67 Antibody (MA5-14520) in IHC (P)','appAbv':'IHC (P)','appName':'Immunohistochemistry (Paraffin)','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'MA5-14520-KI-67-IHCP-2-20230519_140711.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'83734','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki-67-humanbreasttissue-IHC-20160531134932.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki-67-humanbreasttissue-IHC-20160531134932.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA514520-Ki-67-humanbreasttissue-IHC-20160531134932.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA514520-Ki-67-humanbreasttissue-IHC-20160531134932.jpg?time\u003d20240507','sortOrder':'7','description':'Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human breast tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature, washed with ddH2O and PBS, and then probed with a Ki-67 Antibody (SP6) Rabbit Monoclonal Antibody (Product # MA5-14520) diluted in 3% BSA-PBS at a dilution of 1:20 for 1 hour at 37°C in a humidified chamber. Tissues were washed extensively in PBST and detection was performed using an HRP-conjugated secondary antibody followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.','shortDescription':'Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human breast tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))','title':'Ki-67 Antibody (MA5-14520) in IHC (P)','appAbv':'IHC (P)','appName':'Immunohistochemistry (Paraffin)','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'MA514520-Ki-67-humanbreasttissue-IHC-20160531134932.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'83733','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki-67-humantonsiltissue-IHC-20160531134932.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki-67-humantonsiltissue-IHC-20160531134932.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA514520-Ki-67-humantonsiltissue-IHC-20160531134932.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA514520-Ki-67-humantonsiltissue-IHC-20160531134932.jpg?time\u003d20240507','sortOrder':'8','description':'Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human tonsil tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature, washed with ddH2O and PBS, and then probed with a Ki-67 Antibody (SP6) Rabbit Monoclonal Antibody (Product # MA5-14520) diluted in 3% BSA-PBS at a dilution of 1:20 for 1 hour at 37°C in a humidified chamber. Tissues were washed extensively in PBST and detection was performed using an HRP-conjugated secondary antibody followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.','shortDescription':'Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human tonsil tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))','title':'Ki-67 Antibody (MA5-14520) in IHC (P)','appAbv':'IHC (P)','appName':'Immunohistochemistry (Paraffin)','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'MA514520-Ki-67-humantonsiltissue-IHC-20160531134932.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'23181','imageUrl':'https://www.thermofisher.com/antibody/images/650/Cropped_image_for_websiteMA514520.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/Cropped_image_for_websiteMA514520.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/Cropped_image_for_websiteMA514520.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/Cropped_image_for_websiteMA514520.jpg?time\u003d20240507','sortOrder':'9','description':'Formalin-fixed, paraffin-embedded human high grade invasive breast cancer tissue stained with MA5-14520 (1:400) to detect Ki-67, followed by a peroxidase-conjugated secondary reagent and DAB substrate. Data courtesy of the Innovators Program.','shortDescription':'Formalin-fixed, paraffin-embedded human high grade invasive breast cancer tissue stained with MA5-14520 (1:400) to detect Ki-67, followed by a peroxidase-conjugated secondary reagent and DAB substrate. Data courtesy of the Innovators Program.','altTag':'Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))','title':'Ki-67 Antibody (MA5-14520) in IHC (P)','appAbv':'IHC (P)','appName':'Immunohistochemistry (Paraffin)','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'Cropped_image_for_websiteMA514520.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'9020','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA5-14520_Immunohistochemistry.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA5-14520_Immunohistochemistry.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA5-14520_Immunohistochemistry.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA5-14520_Immunohistochemistry.jpg?time\u003d20240507','sortOrder':'10','description':'Formalin-fixed, paraffin-embedded human tonsil stained with Ki-67 using peroxidase-conjugate and AEC. Note nuclear staining of proliferating cells.','shortDescription':'Formalin-fixed, paraffin-embedded human tonsil stained with Ki-67 using peroxidase-conjugate and AEC. Note nuclear staining of proliferating cells.','altTag':'Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))','title':'Ki-67 Antibody (MA5-14520) in IHC (P)','appAbv':'IHC (P)','appName':'Immunohistochemistry (Paraffin)','type':'Antibody Testing Data','journalText':'','sourceType':'1','benchsci':false,'imageName':'MA5-14520_Immunohistochemistry.jpg','benchSciPubmedId':'0'}],'Published Figures':[],'Advanced Verification':[{'sku':'MA5-14520','imageId':'647982','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki67-AV-ICC-20191209134831.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA514520-Ki67-AV-ICC-20191209134831.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA514520-Ki67-AV-ICC-20191209134831.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA514520-Ki67-AV-ICC-20191209134831.jpg?time\u003d20240507','sortOrder':'1','description':'Detection of altered expression of target protein by cell treatment demonstrates antibody specificity. Immunofluorescence analysis of Ki-67 using Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) shows increased expression of Ki-67 in HeLa cell line upon serum starvation (36 hours) followed by serum release (6 hours). By comparison, reduced expression of Ki-67 was seen in HeLa cell line upon serum starvation (36 hours) alone. {TM}','shortDescription':'Detection of altered expression of target protein by cell treatment demonstrates antibody specificity. Immunofluorescence analysis of Ki-67 using Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) shows increased expression of Ki-67 in HeLa cell line upon serum starvation (36 hours) followed by serum release (6 hours). By comparison, reduced expression of Ki-67 was seen in HeLa cell line upon serum starv... \u003ca href\u003d\'#\' class\u003d\'images-view-more-text\' \u003eView More\u003c/a\u003e','altTag':'Ki-67 Antibody','title':'Ki-67 Antibody (MA5-14520)','appAbv':'TM','appName':'Cell treatment','type':'Advanced Verification','journalText':'','sourceType':'2','benchsci':false,'imageName':'MA514520-Ki67-AV-ICC-20191209134831.jpg','benchSciPubmedId':'0'},{'sku':'MA5-14520','imageId':'1007874','imageUrl':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-KO-1-20230731_142446.jpg?time\u003d20240507','imageUrlFullSize':'https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-KO-1-20230731_142446.jpg?time\u003d20240507','imageUrlMidSize':'https://www.thermofisher.com/antibody/images/250/MA5-14520-KI-67-KO-1-20230731_142446.jpg?time\u003d20240507','imageUrlSmallSize':'https://www.thermofisher.com/antibody/images/150/MA5-14520-KI-67-KO-1-20230731_142446.jpg?time\u003d20240507','sortOrder':'2','description':'Antibody specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. A loss of signal was observed for target protein in Ki-67 KO cell line compared to control cell line using Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520). {KO}','shortDescription':'Antibody specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. A loss of signal was observed for target protein in Ki-67 KO cell line compared to control cell line using Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520). {KO}','altTag':'Ki-67 Antibody','title':'Ki-67 Antibody (MA5-14520)','appAbv':'KO','appName':'Knockout','type':'Advanced Verification','journalText':'','sourceType':'2','benchsci':false,'imageName':'MA5-14520-KI-67-KO-1-20230731_142446.jpg','benchSciPubmedId':'0'}]}" image-displayed-id="'647983'" product-sub-type="'antibody_primary'" prod-type="'antibody'" page-type="PDP" product-id="'MA5-14520'"> <div class="tabs"> <ul class="nav nav-pills"> <li class="tab" onclick="window.THERMO_FISHER.inp.onTabClick(event, this)" data-tabname="Antibody Testing Data"> <a class="tab-text"> Antibody Testing Data (8) </a> </li> <li class="tab" onclick="window.THERMO_FISHER.inp.onTabClick(event, this)" data-tabname="Advanced Verification"> <a class="tab-text"> Advanced Verification (2) </a> </li> </ul> <div gallery-flt 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class="cert-provider">{{ $ctrl.currentElement.advancedVerification.text }}</div> </div> <h2 class="product-name" ng-show="!$ctrl.isVideo"> Ki-67 Antibody (MA5-14520) in ICC/IF </h2> <div ng-show="!$ctrl.isVideo"> <div class="image-desc"> <div class="product-desc-text viewing-more-long-description"> <span class="image-journal-text" > </span> <span class="short-desc"> Immunofluorescence analysis of Ki-67 was performed using 70% confluent log phase HeLa cells serum starved (SS) for 36 hours followed by serum release (SR) for 6 hours. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:250 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) H... <a href="#" class="images-view-more-text" >View More</a> </span> <span class="verification-info hide" ng-if="$ctrl.hasVerificationMethod"> <a rel="nofollow" ng-href="{{$ctrl.currentElement.advancedVerification.uri}}" >{{ $ctrl.currentElement.advancedVerification.fullName }} validation info.</a> </span> <a href="#" class="images-view-more-text hide" ng-if="$ctrl.showViewMore" onclick="window.THERMO_FISHER.inp.openImageGalleryModal(event, this)"> View more </a> </div> </div> <div class="img-desc-footer"> <div class="benchsci-pubmed-footer"> <div ng-cloak ng-if="$ctrl.currentElement.benchsci || $ctrl.sourceType === '3'" class="images-benchsci-footer"> <div class="images-benchsci-link" tabindex="0"> <span>Published figure supplied by</span> <span class="icon-benchsci-logo"> <svg id="Layer_1" data-name="Layer 1" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 89.75 23.21"><defs><style>.cls-1{fill:#222222;}</style></defs><title>benchsci-logo</title><g id="logo-blue-copy-3"><g id="logo-blue-copy-2"><path id="path14" class="cls-1" d="M34.54,11.49a2.45,2.45,0,0,0,1.59-2.34c0-1.69-1.21-2.94-3.32-2.94H28.88v10.9h4.21a3.06,3.06,0,0,0,3.37-3A2.57,2.57,0,0,0,34.54,11.49ZM31,8h1.49c1,0,1.57.53,1.57,1.36a1.36,1.36,0,0,1-1.55,1.37H31Zm1.72,7.35H31V12.47h1.75a1.42,1.42,0,0,1,1.62,1.46C34.34,14.79,33.72,15.34,32.69,15.34Z"/><path id="path16" class="cls-1" d="M41.34,9.32a3.8,3.8,0,0,0-3.72,4,3.83,3.83,0,0,0,3.91,4.05A3.39,3.39,0,0,0,45,15l-1.71-.51a1.67,1.67,0,0,1-1.72,1.15,1.85,1.85,0,0,1-1.91-1.73H45s0-.34,0-.63C45.09,10.81,43.69,9.32,41.34,9.32Zm-1.66,3.15A1.63,1.63,0,0,1,41.37,11a1.52,1.52,0,0,1,1.69,1.49Z"/><path id="path18" class="cls-1" d="M50.58,9.35a2.48,2.48,0,0,0-2.18,1.14v-1h-2v7.57h2.05V12.75a1.42,1.42,0,0,1,1.41-1.57,1.34,1.34,0,0,1,1.4,1.52v4.42h2V12.35C53.32,10.68,52.46,9.35,50.58,9.35Z"/><path id="path20" class="cls-1" d="M58.2,15.47a1.94,1.94,0,0,1-1.94-2.14,1.92,1.92,0,0,1,1.91-2.12,1.64,1.64,0,0,1,1.67,1.27l1.83-.61a3.45,3.45,0,0,0-3.55-2.55,3.83,3.83,0,0,0-2.82,1.16,3.88,3.88,0,0,0-1.1,2.85,3.9,3.9,0,0,0,4,4,3.5,3.5,0,0,0,3.53-2.55l-1.8-.6A1.72,1.72,0,0,1,58.2,15.47Z"/><path id="path22" class="cls-1" d="M67,9.35a2.72,2.72,0,0,0-2.07.83V6h-2V17.12h2V12.67a1.43,1.43,0,0,1,1.42-1.48,1.34,1.34,0,0,1,1.4,1.53v4.41h2V12.35A2.67,2.67,0,0,0,67,9.35Z"/><path id="path24" class="cls-1" d="M75.82,11.05l-1.63-.35a1.58,1.58,0,0,1-1.4-1.59A1.93,1.93,0,0,1,74.9,7.3a2.21,2.21,0,0,1,2.3,1.86l1.36-.48a3.73,3.73,0,0,0-7.29.54,3,3,0,0,0,2.67,3l1.55.33c1.09.24,1.63.91,1.63,1.7,0,.95-.74,1.74-2.25,1.74a2.51,2.51,0,0,1-1.79-.63,2.45,2.45,0,0,1-.82-1.71l-1.45.46a3.79,3.79,0,0,0,4.08,3.24c2.32,0,3.76-1.52,3.76-3.22C78.65,12.59,77.63,11.45,75.82,11.05Z"/><path id="path26" class="cls-1" d="M83.25,16A2.33,2.33,0,0,1,81,13.41a2.31,2.31,0,0,1,2.24-2.59,1.93,1.93,0,0,1,2,1.57l1.31-.55a3.22,3.22,0,0,0-3.29-2.35,3.7,3.7,0,0,0-3.72,3.92,3.75,3.75,0,0,0,3.74,3.94A3.41,3.41,0,0,0,86.59,15l-1.28-.55A2,2,0,0,1,83.25,16Z"/><path id="path28" class="cls-1" d="M88.69,5.89a1,1,0,1,0,.75.29A1,1,0,0,0,88.69,5.89Z"/><polygon id="rect30" class="cls-1" points="87.99 9.72 89.42 9.72 89.42 17.11 87.99 17.11 87.99 9.72"/><path id="path32" class="cls-1" d="M14.58,8.87A4.1,4.1,0,0,0,15.8,6H14.31a2.62,2.62,0,0,1-.76,1.87L11.66,9.7l-2-2A2.61,2.61,0,0,1,9,6H7.53A4.09,4.09,0,0,0,8.74,8.87l1.87,1.87L8.74,12.61a4.08,4.08,0,0,0-1.21,2.92v2.29H9.18V16.73h1.66v1.09h1.64V16.73h1.65v1.09H15.8V15.53a4.11,4.11,0,0,0-1.21-2.92l-1.38-1.36-1,1.05,1.37,1.36a2.63,2.63,0,0,1,.77,1.58H9a2.68,2.68,0,0,1,.76-1.58Z"/><path id="path34" class="cls-1" d="M11.61,23.21a11.61,11.61,0,1,1,11.6-11.6A11.6,11.6,0,0,1,11.61,23.21Zm0-21.89A10.29,10.29,0,1,0,21.9,11.61,10.28,10.28,0,0,0,11.61,1.32Z"/></g></g></svg> </span> <span id="bechsci-tooltip-{{$ctrl.productId}}" class="bechsci-tooltip-icon" data-toggle="tooltip" ng-click="$ctrl.showBechSciTooltip()" close-tooltip="$ctrl.closeBechSciTooltip()" data-html="true" title="Clicking this link will redirect you to the <a href='https://www.benchsci.com/' target='_blank'> BenchSci</a> website that provides third-party scientific content. 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<image-gallery-key-nav pdp-gallery="true"></image-gallery-key-nav> <div class="film-strip"> <div id="custom-scrollbar" class="set-of-images"> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="647983" data-index="0"> <img src="https://www.thermofisher.com/antibody/images/150/MA514520-Ki67-ICC-20191209134648.jpg?time=20240507" alt="Ki-67 Antibody in Immunocytochemistry (ICC/IF)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1007873" data-index="1"> <img src="https://www.thermofisher.com/antibody/images/150/MA5-14520-KI-67-ICCIF-1-20230731_142446.jpg?time=20240507" alt="Ki-67 Antibody in Immunocytochemistry (ICC/IF)"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="987581" data-index="2"> <img 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<div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="647982" data-index="8"> <img src="https://www.thermofisher.com/antibody/images/150/MA514520-Ki67-AV-ICC-20191209134831.jpg?time=20240507" alt="Ki-67 Antibody"/> </div> <div image-gallery-fade-server-side class="img-flipcard" onclick="window.THERMO_FISHER.inp.onClickFilmstripItem(event, this)" data-imgid="1007874" data-index="9"> <img src="https://www.thermofisher.com/antibody/images/150/MA5-14520-KI-67-KO-1-20230731_142446.jpg?time=20240507" alt="Ki-67 Antibody"/> </div> </div> </div> </div> </div> <noscript> <div itemscope itemtype="http://schema.org/ImageGallery"> <h2>Product Image Gallery</h2> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA514520-Ki67-ICC-20191209134648.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunocytochemistry (ICC/IF)" title="Ki-67 Antibody (MA5-14520) in ICC/IF"> <figcaption itemprop="caption">Immunofluorescence analysis of Ki-67 was performed using 70% confluent log phase HeLa cells serum starved (SS) for 36 hours followed by serum release (SR) for 6 hours. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:250 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790) at a dilution of 1:2000 for 45 minutes at room temperature (Panel a: green). Nuclei (Panel b: blue) were stained with SlowFade® Gold Antifade Mountant with DAPI (Product # S36938). F-actin (Panel c: red) was stained with Rhodamine Phalloidin (Product # R415, 1:300). Panel d represents the merged image showing nuclear localization. Panel e represents the serum starved cells with reduced signal. Panel f represents control cells with no primary antibody to assess background. The images were captured at 60X magnification.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-ICCIF-1-20230731_142446.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunocytochemistry (ICC/IF)" title="Ki-67 Antibody (MA5-14520) in ICC/IF"> <figcaption itemprop="caption">Knockout of Ki-67 was achieved by CRISPR-Cas9 genome editing using LentiArray™ Lentiviral sgRNA (Product # A32042, Assay ID CRISPR955684_LV) and LentiArray Cas9 Lentivirus (Product # A32064). Immunofluorescence analysis was performed on HeLa wild type cells (panel a,d), HeLa Cas9 control cells (panel b,e) and HeLa Ki-67 KO cells (panel c, f). Cells were fixed, permeabilized, and labeled with Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520, 1:500 dilution), followed by Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor™ Plus 488 (Product#A32790, 1:2000 dilution). Nuclei (blue) were stained using ProLong™ Diamond Antifade Mountant with DAPI (Product # P36962), and Rhodamine Phalloidin (Product # R415, 1:300) was used for cytoskeletal F-actin (red) staining. Loss of signal (panel c,f) upon CRISPR mediated knockout (KO) confirms that antibody is specific to Ki-67 (green). The images were captured at 60X magnification.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-IHCP-1-20230519_140711.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))" title="Ki-67 Antibody (MA5-14520) in IHC (P)"> <figcaption itemprop="caption">Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - High pH (10X) (Product # 00-4956-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Following antigen retrieval, the sections were blocked with 2% normal goat serum in 1X PBS for 45 minutes at room temperature and then probed with or without Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:100 dilution in 0.1% normal goat serum overnight at 4 degree Celsius in a humidified chamber. Detection was performed using Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at a dilution of 1:2000 in 0.1% normal goat serum for 45 minutes at room temperature. ReadyProbes™ Tissue Autofluorescence Quenching Kit (Product # R37630) was used to quench autofluorescence from the tissues. Nuclei were stained with DAPI (Product # D1306) and the sections were mounted using ProLong™ Glass Antifade Mountant (Product # P36984). The images were captured on EVOS™ M7000 Imaging System (Product # AMF7000) at 20X magnification and externally deconvoluted.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-IHCP-2-20230519_140711.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))" title="Ki-67 Antibody (MA5-14520) in IHC (P)"> <figcaption itemprop="caption">Immunohistochemical analysis of Ki-67 was performed using formalin-fixed paraffin-embedded human colon adenocarcinoma tissue sections. To expose the target protein, heat-induced epitope retrieval was performed on de-paraffinized sections using eBioscience™ IHC Antigen Retrieval Solution - Low pH (10X) (Product # 00-4955-58) diluted to 1X solution in water in a decloaking chamber at 110 degree Celsius for 15 minutes. Following antigen retrieval, the sections were blocked with 2% normal goat serum in 1X PBS for 45 minutes at room temperature and then probed with or without Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520) at 1:100 dilution in 0.1% normal goat serum overnight at 4 degree Celsius in a humidified chamber. Detection was performed using Goat anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32731) at a dilution of 1:2000 in 0.1% normal goat serum for 45 minutes at room temperature. ReadyProbes™ Tissue Autofluorescence Quenching Kit (Product # R37630) was used to quench autofluorescence from the tissues. Nuclei were stained with DAPI (Product # D1306) and the sections were mounted using ProLong™ Glass Antifade Mountant (Product # P36984). The images were captured on EVOS™ M7000 Imaging System (Product # AMF7000) at 20X magnification and externally deconvoluted.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA514520-Ki-67-humanbreasttissue-IHC-20160531134932.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))" title="Ki-67 Antibody (MA5-14520) in IHC (P)"> <figcaption itemprop="caption">Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human breast tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature, washed with ddH2O and PBS, and then probed with a Ki-67 Antibody (SP6) Rabbit Monoclonal Antibody (Product # MA5-14520) diluted in 3% BSA-PBS at a dilution of 1:20 for 1 hour at 37°C in a humidified chamber. Tissues were washed extensively in PBST and detection was performed using an HRP-conjugated secondary antibody followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA514520-Ki-67-humantonsiltissue-IHC-20160531134932.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))" title="Ki-67 Antibody (MA5-14520) in IHC (P)"> <figcaption itemprop="caption">Immunohistochemistry analysis of Ki-67 (SP6) showing staining in the nucleus of paraffin-embedded human tonsil tissue (right) compared to a negative control without primary antibody (left). To expose target proteins, antigen retrieval was performed using 10mM sodium citrate (pH 6.0), microwaved for 8-15 min. Following antigen retrieval, tissues were blocked in 3% H2O2-methanol for 15 min at room temperature, washed with ddH2O and PBS, and then probed with a Ki-67 Antibody (SP6) Rabbit Monoclonal Antibody (Product # MA5-14520) diluted in 3% BSA-PBS at a dilution of 1:20 for 1 hour at 37°C in a humidified chamber. Tissues were washed extensively in PBST and detection was performed using an HRP-conjugated secondary antibody followed by colorimetric detection using a DAB kit. Tissues were counterstained with hematoxylin and dehydrated with ethanol and xylene to prep for mounting.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/Cropped_image_for_websiteMA514520.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))" title="Ki-67 Antibody (MA5-14520) in IHC (P)"> <figcaption itemprop="caption">Formalin-fixed, paraffin-embedded human high grade invasive breast cancer tissue stained with MA5-14520 (1:400) to detect Ki-67, followed by a peroxidase-conjugated secondary reagent and DAB substrate. Data courtesy of the Innovators Program.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA5-14520_Immunohistochemistry.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody in Immunohistochemistry (Paraffin) (IHC (P))" title="Ki-67 Antibody (MA5-14520) in IHC (P)"> <figcaption itemprop="caption">Formalin-fixed, paraffin-embedded human tonsil stained with Ki-67 using peroxidase-conjugate and AEC. Note nuclear staining of proliferating cells.</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA514520-Ki67-AV-ICC-20191209134831.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody" title="Ki-67 Antibody (MA5-14520)"> <figcaption itemprop="caption">Detection of altered expression of target protein by cell treatment demonstrates antibody specificity. Immunofluorescence analysis of Ki-67 using Ki-67 Monoclonal Antibody (SP6) (Product # MA5-14520) shows increased expression of Ki-67 in HeLa cell line upon serum starvation (36 hours) followed by serum release (6 hours). By comparison, reduced expression of Ki-67 was seen in HeLa cell line upon serum starvation (36 hours) alone. {TM}</figcaption> </figure> </div> <div> <hr> <figure itemprop="image" itemscope itemtype="http://schema.org/ImageObject"> <img src="https://www.thermofisher.com/antibody/images/650/MA5-14520-KI-67-KO-1-20230731_142446.jpg?time=20240507?time=20240507" alt="Ki-67 Antibody" title="Ki-67 Antibody (MA5-14520)"> <figcaption itemprop="caption">Antibody specificity was demonstrated by CRISPR-Cas9 mediated knockout of target protein. A loss of signal was observed for target protein in Ki-67 KO cell line compared to control cell line using Ki-67 Recombinant Rabbit Monoclonal Antibody (SP6) (Product # MA5-14520). {KO}</figcaption> </figure> </div> </div> </noscript> <div id="tf-related-products-container-new"></div> <div class="product-details"> <div class="container"> <div class="row"> <div class="large-span-12 medium-span-12 small-span-12"> <h2 class="pdp-sub-heading product_details_heading">Product Details</h2></div> <div class="hidden-sku"> <h2>MA5-14520</h2> </div> <div class="product-detail-section tested-app-section new-tbl-design product-detail-section table-spec"> <div class="product-container-head"> <div class="product-item"> Applications </div> <div class="product-item dilution-lbl-head "> Tested Dilution </div> <div class="product-item published-applications"> Publications </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Western Blot (WB)</h2></div> <div class="product-item "> <span class="dilution-lbl">1:100</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#WB-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 12 publications</span> <span class="mobile-view">12 publications</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Immunohistochemistry (IHC)</h2></div> <div class="product-item "> <span class="dilution-lbl dilution-lbl-dash">-</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#IHC-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 636 publications</span> <span class="mobile-view">636 publications</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Immunohistochemistry (Paraffin) (IHC (P))</h2></div> <div class="product-item "> <span class="dilution-lbl">1:100-1:200</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#IHCP-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 53 publications</span> <span class="mobile-view">53 publications</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Immunohistochemistry (Frozen) (IHC (F))</h2></div> <div class="product-item "> <span class="dilution-lbl dilution-lbl-dash">-</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#IHCF-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 11 publications</span> <span class="mobile-view">11 publications</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Immunocytochemistry (ICC/IF)</h2></div> <div class="product-item "> <span class="dilution-lbl">1:250-1:500</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#ICCIF-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 71 publications</span> <span class="mobile-view">71 publications</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Flow Cytometry (Flow)</h2></div> <div class="product-item "> <span class="dilution-lbl">1:1,000</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#Flow-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 7 publications</span> <span class="mobile-view">7 publications</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Neutralization (Neu)</h2></div> <div class="product-item "> <span class="dilution-lbl dilution-lbl-dash">-</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#Neu-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 1 publication</span> <span class="mobile-view">1 publication</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Functional Assay (Functional)</h2></div> <div class="product-item "> <span class="dilution-lbl dilution-lbl-dash">-</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#Functional-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 1 publication</span> <span class="mobile-view">1 publication</span></a> </div> </div> <div class="product-container-body"> <div class="product-item"> <h2>Miscellaneous PubMed (Misc)</h2></div> <div class="product-item "> <span class="dilution-lbl dilution-lbl-dash">-</span> </div> <div class="product-item"> <a class="animated-scroll" onclick="window.THERMO_FISHER.pdp.inp.handleClickReferenceProductDetails(event,this,'a[href="#Misc-content&quot]')" data-target="References" href="#references-component-id"> <span class="desktop-view">View 3 publications</span> <span class="mobile-view">3 publications</span></a> </div> </div> </div> <div class="product-detail-section tested-app-section new-tbl-design product-specific-section table-spec"> <div class="product-container-head"> <div class="product-item">Product Specifications</div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Species Reactivity</h2> </div> <div class="product-item left-flex-cls"> <span title="Homo sapiens">Human,</span> <span title="Mus musculus">Mouse,</span> <span title="Rattus">Rat</span> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Published species</h2> </div> <div class="product-item left-flex-cls"> <span>Bovine,</span> <span>Cat,</span> <span>Dog,</span> <span>Guinea pig,</span> <span>Hamster,</span> <span>Human,</span> <span>Mouse,</span> <span>Non-human primate,</span> <span>Pig,</span> <span>Rabbit,</span> <span>Rat,</span> <span>Rhesus monkey,</span> <span>Sheep</span> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2> Host/Isotype</h2> </div> <div class="product-item left-flex-cls"> <span title="Oryctolagus cuniculus">Rabbit / IgG</span> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Expression System</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> proprietary </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Class</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Recombinant Monoclonal </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Type</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Antibody </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Clone</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> SP6 </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Immunogen </h2> </div> <div class="product-item left-flex-cls">Synthetic peptide within Human Ki67 aa 1200-1300 <script type="text/javascript"> if (typeof window.$mangular === 'undefined' || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = '[{"targetFamily":"Ki-67","uniProtId":"P46013-1","ncbiNodeId":"9606","antigenRange":"1200-1300","antigenLength":"3256","antigenImageFileName":"MA5-14520_Ki-67_P46013-1_rabbit.svg","antigenImageFileNamePDP":"MA5-14520_Ki-67_P46013-1_rabbit_PDP.jpeg","sortOrder":"1"}]'; $mangular.isB2BCMGT = '"false"'; $mangular.isEpitopesModalImageMultiSizeEnabled = 'true'; </script> <div class="antigen-link" ng-click="$ctrl.openModal()"> <a href="">View immunogen <span class="antigen-link-icon"> <?xml version="1.0" encoding="utf-8"?>  <svg version="1.1" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink" x="0px" y="0px" viewBox="0 0 20 20" style="enable-background:new 0 0 20 20;" xml:space="preserve"> <style type="text/css"> .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;} </style> <g id="Layer_1"> <line class="st0" x1="1.2" y1="2.5" x2="17.6" y2="2.5"/> <path d="M16.4,2.5"/> <g> <path d="M15.4,13.5"/> <path d="M15,14.9l2.8-2.8L15,9.3c0,0,0,0.9,0,1.9h-13V13h13C15.1,14,15.1,14.9,15,14.9z"/> <path d="M4.9,19.3l-2.8-2.8l2.8-2.8c0,0,0,0.9,0,1.9h13v1.8h-13C4.9,18.4,4.9,19.3,4.9,19.3z"/> </g> <g> <path d="M15.4,3.4"/> <path d="M15,6l2.8-2.8L15,0.3c0,0,0,0.9,0,1.9h-13V4h13C15.1,5.1,15.1,5.9,15,6z"/> <path d="M4.9,10.4L2.1,7.6l2.8-2.8c0,0,0,0.9,0,1.9h13v1.8h-13C4.9,9.5,4.9,10.4,4.9,10.4z"/> </g> <g> <path d="M2.8,8.1C1.3,8.1,0,6.9,0,5.4s1.3-2.7,2.8-2.7v1C1.8,3.6,1,4.4,1,5.4s0.8,1.8,1.8,1.8V8.1z"/> </g> <g> <path d="M17.2,12.6c1.5,0,2.8-1.2,2.8-2.8s-1.3-2.8-2.8-2.8v1c1,0,1.8,0.8,1.8,1.8s-0.8,1.8-1.8,1.8V12.6z"/> </g> <g> <path d="M2.8,17.1c-1.5,0-2.8-1.2-2.8-2.8s1.3-2.8,2.8-2.8v1c-1,0-1.8,0.8-1.8,1.8s0.8,1.8,1.8,1.8V17.1z"/> </g> </g> <g id="Layer_1_copy"> <path class="st1" d="M17.4,12.5c1.4-0.1,2.6-1.3,2.6-2.7c0-1.3-0.9-2.4-2.1-2.7V6.7h-13c0-1.1,0-1.9,0-1.9L2.6,7.1 C1.7,7,1,6.3,1,5.4C1,4.6,1.5,4,2.1,3.7V4h13c0,1,0,1.9,0,1.9l2.8-2.8L15,0.3c0,0,0,0.9,0,1.9h-13v0.4C0.9,3,0,4.1,0,5.4 C0,6.8,1.1,8,2.6,8.1l2.3,2.3c0,0,0-0.9,0-1.9h13V8.2C18.5,8.4,19,9.1,19,9.8c0,0.9-0.7,1.7-1.7,1.7L15,9.3c0,0,0,0.9,0,1.9h-13 v0.4C0.9,12,0,13,0,14.3c0,1.5,1.2,2.6,2.6,2.7l2.3,2.3c0,0,0-0.9,0-1.9h13v-1.8h-13c0-1.1,0-1.9,0-1.9L2.6,16 C1.7,15.9,1,15.2,1,14.3c0-0.7,0.5-1.3,1.1-1.6V13h13c0,1,0,1.9,0,1.9L17.4,12.5z"/> </g> </svg> </span> </a> </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Conjugate</h2> </div> <div class="product-item left-flex-cls"> <a ng-if="$ctrl.checkConjugate('Unconjugated ') && ''.trim() != ''" href="" ng-attr-target="{{$ctrl.getRequestCustomLinkTarget()}}" class="conjugate-value">Unconjugated </a> <span ng-if="($ctrl.checkConjugate('Unconjugated ') && ''.trim() == '')" class="conjugate-value">Unconjugated </span> <span ng-if="!$ctrl.checkConjugate('Unconjugated ')" class="conjugate-value">Unconjugated </span> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Form</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Liquid </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Concentration</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> 0.031 mg/mL </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Purification</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Protein A </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Storage buffer</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> PBS, pH 7.2, with 1% BSA </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Contains</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> 0.1% sodium azide </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Storage conditions</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"> <h2>Shipping conditions</h2> </div> <div class="product-item left-flex-cls"> <div class="product-value"> Ambient (domestic); Wet ice (international) </div> </div> </div> <div class="product-container-body pcb1-2"> <div class="product-item"><h2>RRID <span id="rrid-tooltip" class="rrid-tooltip-icon" ng-include="'/order/genome-database/webapp/assets/core/img/svg/mono_tooltip.svg'" data-toggle="tooltip" ng-click="$ctrl.showRridTooltip()" close-tooltip="$ctrl.closeRridTooltip()" title="Research Resource Identifiers (#RRID) are ID numbers assigned to help researchers cite key resources in the biomedical literature to improve transparency of research methods."> </span></h2> </div> <div class="product-item left-flex-cls">AB_10979488</div> </div> </div> <div class="product-specific-details"> <div class="product-specific-details-tbl product-specific-add-border" > <div class="product-info-para"> <h4 class="product-info-para-heading"> Product Specific Information </h4> <p>Staining of formalin-fixed tissues requires boiling tissue section in 10 mM citrate buffer, pH 6.0 for 10-20 minutes followed by cooling at room temperature for 20 minutes.<br /><br />Recommended positive controls:<br /><br />IHC (P) - Human tonsil and testis tissue, common marmoset spleen tissue, rat esophagus, small intestine and liver tissue, mouse embryonic skin tissue<br /><br />IHC (F) - Rat lymph node tissue, transgenic mouse spinal cord tissue<br /><br />ICC/IF - HAP1 cells, human cardiac stem cells, HEp-2 cells, rat cardiomyocytes<br /><br />Flow - HAP1 cells</p> </div> <div class="product-info-para"> <h4 class="product-info-para-heading"> Target Information </h4> <p class="product-specific-target-info">Ki-67 is a nuclear protein that is expressed during various stages in the cell cycle, particularly during late G1, S, G2, and M phases. The protein has a forkhead associated domain (FHA) through which it associates with euchromatin at the perichromosomal layer, the centromeric heterochromatin, and the nucleolus. Ki-67 is shown to have a cell cycle dependent topographical distribution with perinucleolar expression at G1, expression in the nuclear matrix at G2, and expression on the chromosomes during M phase. Ki-67 is commonly used as a proliferation marker because it is not detected in G0 cells, but increases steadily from G1 through mitosis. Ki-67 antibodies are useful in establishing the cell growing fraction in neoplasms. In neoplastic tissues, the prognostic value is comparable to the tritiated thymidine-labelling index. The correlation between low Ki-67 index and histologically low-grade tumors is strong. Ki-67 is routinely used as a neuronal marker of cell cycling and proliferation.</p> </div> <p class="product-details-regulatoryStmt">For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.</p> </div> <div class="product-detail-panel-builder"> <tf-promo-ad ng-if="$ctrl.showPromoAd" show-promo-ad="$ctrl.showPromoAd"></tf-promo-ad> </div> </div> </div> </div> </div> <div id="rootPdpDocLoader"></div> <div id="tf-related-products-container" ng-show="emptyRelatedProductsWidget === false" > <related-products-container ng-if="showRelatedProductsWidget === true" base-url="'/api/magellan/related-products-ui/widget/v2/'" product-type="'antibody'" product-sub-type="'primary'" product-id="'MA514520'" country-code="'sg'" iso-language="'en'" > </related-products-container> </div> <div class="tf-pdp-divider" ng-if="emptyRelatedProductsWidget === false" ></div> <div class="references reference-section-3" id="references-component-id"> <div id="references-section-id"> <reference-section ng-if="loadReferences" default-display-card-limit="3" reference-count="795" sub-type="'Antibody'" 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<noscript> <div itemscope itemtype="https://schema.org/ScholarlyArticle"> <h2>Product References</h2> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36384142"> <div itemprop="name">Astrocyte endfoot formation controls the termination of oligodendrocyte precursor cell perivascular migration during development.</div> </a> <div itemprop="about">Neuron</div> <div itemprop="author">Su Y,Wang X,Yang Y,Chen L,Xia W,Hoi KK,Li H,Wang Q,Yu G,Chen X,Wang S,Wang Y,Xiao L,Verkhratsky A,Fancy SPJ,Yi C,Niu J</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to demonstrate a correlation between the developmental formation of astrocytic endfeet on vessels and the termination of OPC perivascular migration.</div> <div itemprodp="datePublished">Wed Jan 18 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36661521"> <div itemprop="name">Single Prolonged Stress Decreases the Level of Adult Hippocampal Neurogenesis in C57BL/6, but Not in House Mice.</div> </a> <div itemprop="about">Current issues in molecular biology</div> <div itemprop="author">Kurilova E,Sidorova M,Tuchina O</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to model PTSD in long-inbred C57BL/6 and wild-derived (house) female mice.</div> <div itemprodp="datePublished">Fri Jan 06 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37252415"> <div itemprop="name">Recurrent Desmoid Fibromatosis of the Thyroid Gland: A Diagnostic Challenge.</div> </a> <div itemprop="about">Journal of the ASEAN Federation of Endocrine Societies</div> <div itemprop="author">Singh BK,Chumber S,Rathore YS,Agarwal S,Rastogi S,Surabhi V</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that the case is being reported for its rarity and the discussion of its differential diagnoses.</div> <div itemprodp="datePublished">Thu Jun 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37239012"> <div itemprop="name">Enriched Environment Induces Sex-Specific Changes in the Adult Neurogenesis, Cytokine and miRNA Expression in Rat Hippocampus.</div> </a> <div itemprop="about">Biomedicines</div> <div itemprop="author">Vinogradova A,Sysova M,Smirnova P,Sidorova M,Turkin A,Kurilova E,Tuchina O</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to study the behavior and hippocampal neurogenesis in adult male and female Wistar rats that were housed in an enriched environment (EE) for two months. Both EE males and females performed better than control animals in a Barnes maze, meaning that EE enhances spatial memory.</div> <div itemprodp="datePublished">Tue May 02 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36624306"> <div itemprop="name">High-fat diet and estrogen modulate the gut microbiota in a sex-dependent manner in mice.</div> </a> <div itemprop="about">Communications biology</div> <div itemprop="author">Hases L,Stepanauskaite L,Birgersson M,Brusselaers N,Schuppe-Koistinen I,Archer A,Engstrand L,Williams C</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to report clear host sex differences along with remarkably sex-dependent responses to high-fat diet.</div> <div itemprodp="datePublished">Mon Jan 09 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36765089"> <div itemprop="name">Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Luo Z,Xin D,Liao Y,Berry K,Ogurek S,Zhang F,Zhang L,Zhao C,Rao R,Dong X,Li H,Yu J,Lin Y,Huang G,Xu L,Xin M,Nishinakamura R,Yu J,Kool M,Pfister SM,Roussel MF,Zhou W,Weiss WA,Andreassen P,Lu QR</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to demonstrate that CTDNEP1 is a tumor suppressor in highly aggressive MYC-driven medulloblastomas by controlling MYC activity and mitotic fidelity, pointing to a CTDNEP1-dependent targetable therapeutic vulnerability.</div> <div itemprodp="datePublished">Fri Feb 10 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36810913"> <div itemprop="name">An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1.</div> </a> <div itemprop="about">British journal of cancer</div> <div itemprop="author">Aftab F,Rodriguez-Fuguet A,Silva L,Kobayashi IS,Sun J,Politi K,Levantini E,Zhang W,Kobayashi SS,Zhang WC</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to investigate the inhibitory effects of AICAR on MUC1 activity in EGFR-mutant lung cancer cells.</div> <div itemprodp="datePublished">Mon May 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37414790"> <div itemprop="name">TET2 and TET3 loss disrupts small intestine differentiation and homeostasis.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Ansari I,Solé-Boldo L,Ridnik M,Gutekunst J,Gilliam O,Korshko M,Liwinski T,Jickeli B,Weinberg-Corem N,Shoshkes-Carmel M,Pikarsky E,Elinav E,Lyko F,Bergman Y</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that ablation of TET2/3 in intestinal epithelial cells results in a murine phenotype characterized by a severe homeostasis imbalance in the small intestine.</div> <div itemprodp="datePublished">Thu Jul 06 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37587100"> <div itemprop="name">Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Freitas-Andrade M,Comin CH,Van Dyken P,Ouellette J,Raman-Nair J,Blakeley N,Liu QY,Leclerc S,Pan Y,Liu Z,Carrier M,Thakur K,Savard A,Rurak GM,Tremblay MÈ,Salmaso N,da F Costa L,Coppola G,Lacoste B</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to identify astroglial Hmgb1 as an important player in postnatal gliovascular maturation.</div> <div itemprodp="datePublished">Wed Aug 16 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36685042"> <div itemprop="name">Step-dose IL-7 treatment promotes systemic expansion of T cells and alters immune cell landscape in blood and lymph nodes.</div> </a> <div itemprop="about">iScience</div> <div itemprop="author">Pandit H,Valentin A,Angel M,Deleage C,Bergamaschi C,Bear J,Sowder R,Felber BK,Pavlakis GN</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to study treatment of T cells and immune cell landscape in blood and lymph nodes.</div> <div itemprodp="datePublished">Fri Feb 17 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37163605"> <div itemprop="name">Deficiency in mammalian STN1 promotes colon cancer development via inhibiting DNA repair.</div> </a> <div itemprop="about">Science advances</div> <div itemprop="author">Nguyen DD,Kim E,Le NT,Ding X,Jaiswal RK,Kostlan RJ,Nguyen TNT,Shiva O,Le MT,Chai W</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to identify STN1 deficiency as a risk factor for CRC and implicates the previously unknown STN1-BER axis in protecting colon tissues from oxidative damage, therefore providing insights into the CRC tumor-suppressing mechanism.</div> <div itemprodp="datePublished">Wed May 10 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37365326"> <div itemprop="name">Interferon signaling promotes tolerance to chromosomal instability during metastatic evolution in renal cancer.</div> </a> <div itemprop="about">Nature cancer</div> <div itemprop="author">Perelli L,Carbone F,Zhang L,Huang JK,Le C,Khan H,Citron F,Del Poggetto E,Gutschner T,Tomihara H,Soeung M,Minelli R,Srinivasan S,Peoples M,Lam TNA,Lundgren S,Xia R,Zhu C,Mohamed AMT,Zhang J,Sircar K,Sgambato A,Gao J,Jonasch E,Draetta GF,Futreal A,Bakouny Z,Van Allen EM,Choueiri T,Signoretti S,Msaouel P,Litchfield K,Turajlic S,Wang L,Chen YB,Di Natale RG,Hakimi AA,Giuliani V,Heffernan TP,Viale A,Bristow CA,Tannir NM,Carugo A,Genovese G</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to provide critical knowledge on drivers of renal cell carcinoma progression and defines the primary role of interferon signaling in constraining the propagation of aneuploid clones in cancer evolution.</div> <div itemprodp="datePublished">Sat Jul 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37369732"> <div itemprop="name">Suspended hydrogel culture as a method to scale up intestinal organoids.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Co JY,Klein JA,Kang S,Homan KA</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to demonstrate the compatibility of this method with multiple culture formats, and provide examples of suspended BME hydrogel organoids in downstream applications: implementation in a medium-throughput drug screen and generation of Transwell monolayers for barrier evaluation.</div> <div itemprodp="datePublished">Tue Jun 27 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36782279"> <div itemprop="name">IFN-γ-STAT1-mediated CD8<sup>+</sup> T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury.</div> </a> <div itemprop="about">Inflammation and regeneration</div> <div itemprop="author">Wang J,Xu L,Peng D,Zhu Y,Gu Z,Yao Y,Li H,Cao X,Fu CY,Zheng M,Song X,Ding Y,Shen Y,Zhong J,Chen YY,Hu J,Wang LL</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to identify INF-γ as a critical mediator of CD8+ T-cell-NSC cross talk and a potential node for therapeutic intervention in spinal cord injury.</div> <div itemprodp="datePublished">Mon Feb 13 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36823182"> <div itemprop="name">Rhamnazin Enhanced Anti-Tumor Efficacy of Anti-PD-1 Therapy for Lung Cancer in Mice through Inhibition of PD-L1 Expression.</div> </a> <div itemprop="about">The Tohoku journal of experimental medicine</div> <div itemprop="author">Wang SS,Liu Y,Zhang XT,Yu DQ</div> <div itemprop="description">MA5-14520 was used in Flow cytometry/Cell sorting to suggest that rhamnazin enhances antitumor effect of anti-PD-1 therapy for lung cancer in mice via inhibition of PD-L1 expression.</div> <div itemprodp="datePublished">Sat May 20 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36774363"> <div itemprop="name">Murine neonatal cardiac B cells promote cardiomyocyte proliferation and heart regeneration.</div> </a> <div itemprop="about">NPJ Regenerative medicine</div> <div itemprop="author">Tan Y,Duan X,Wang B,Liu X,Zhan Z</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to find that the neonatal mice with B cell depletion showed markedly reduced cardiomyocyte proliferation, leading to cardiac dysfunction, fibrosis scar formation, and the complete failure of heart regeneration after apical resection.</div> <div itemprodp="datePublished">Sat Feb 11 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37000125"> <div itemprop="name">Lithium Chloride Exerts Anti-Inflammatory and Neuroprotective Effects by Inhibiting Microglial Activation in LPS-Induced Retinal Injury.</div> </a> <div itemprop="about">Investigative ophthalmology & visual science</div> <div itemprop="author">Wu N,Luo Q,Huang Y,Wan L,Hou X,Jiang Z,Li Y,Qiu J,Chen P,Yu K,Zhuang J,Yang Y</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to demonstrate that LiCl exerts anti-inflammatory and neuroprotective effects by inhibiting microglial activation via the PI3K/Akt/NF-κB pathway in LPS-induced retinal injury.</div> <div itemprodp="datePublished">Wed Mar 01 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37339146"> <div itemprop="name">Anti-angiogenic and anti-proliferative activity of ziziphus leaf extract as a novel potential therapeutic agent for reducing hepatic injury in experimental hamster schistosomiasis.</div> </a> <div itemprop="about">PLoS neglected tropical diseases</div> <div itemprop="author">Alghamdi T,Salem DA,El-Refaei MF</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to evaluate the therapeutic potential of Ziziphus spina-christi leaf extract (ZLE) as an anti-angiogenic, and anti-proliferative agent in hamsters infected with S. mansoni.</div> <div itemprodp="datePublished">Thu Jun 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37500626"> <div itemprop="name">Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Zhou Y,Cui G,Xu H,Chun J,Yang D,Zhang Z,Yang L,Wang J,Wan M,Calvisi DF,Lin S,Chen X,Wang H</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that loss of TP53 cooperates with c-MET to drive hepatocarcinogenesis in vivo.</div> <div itemprodp="datePublished">Thu Jul 27 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37070472"> <div itemprop="name">Hypoxia-inducible factor 1A inhibition overcomes castration resistance of prostate tumors.</div> </a> <div itemprop="about">EMBO molecular medicine</div> <div itemprop="author">Terzic J,Abu El Maaty MA,Lutzing R,Vincent A,El Bizri R,Jung M,Keime C,Metzger D</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that HIF1A in prostatic tumor cells is a critical factor that enables their survival after ADT, and identify it as a target for CRPC management.</div> <div itemprodp="datePublished">Wed Jun 07 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/37697166"> <div itemprop="name">Transcriptional and epigenetic decoding of the microglial aging process.</div> </a> <div itemprop="about">Nature aging</div> <div itemprop="author">Li X,Li Y,Jin Y,Zhang Y,Wu J,Xu Z,Huang Y,Cai L,Gao S,Liu T,Zeng F,Wang Y,Wang W,Yuan TF,Tian H,Shu Y,Guo F,Lu W,Mao Y,Mei X,Rao Y,Peng B</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to map the transcriptional and epigenetic profiles of microglia from 3- to 24-month-old mice.</div> <div itemprodp="datePublished">Sun Oct 01 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36831214"> <div itemprop="name">Dual Targeting of EGFR and MTOR Pathways Inhibits Glioblastoma Growth by Modulating the Tumor Microenvironment.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Sidorov M,Dighe P,Woo RWL,Rodriguez-Brotons A,Chen M,Ice RJ,Vaquero E,Jian D,Desprez PY,Nosrati M,Galvez L,Leng L,Dickinson L,Kashani-Sabet M,McAllister SD,Soroceanu L</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that pharmacological co-targeting of EGFR and MTOR using clinically available drugs represents an effective treatment paradigm for EGFR-driven GBMs, acting both by inhibiting tumor cell growth and modulating the immune tumor microenvironment.</div> <div itemprodp="datePublished">Wed Feb 08 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36059712"> <div itemprop="name">Decellularization of xenografted tumors provides cell-specific <i>in vitro</i> 3D environment.</div> </a> <div itemprop="about">Frontiers in oncology</div> <div itemprop="author">Iazzolino G,Mendibil U,Arnaiz B,Ruiz-de-Angulo A,Azkargorta M,Uribe KB,Khatami N,Elortza F,Olalde B,Gomez-Vallejo V,Llop J,Abarrategi A</div> <div itemprop="description">MA5-14520 was used in Immuno-assay to serve as a proof-of-concept for further potential generation of patient-specific in vitro research models.</div> <div itemprodp="datePublished">Tue Mar 28 00:00:00 EDT 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36111143"> <div itemprop="name">CD36 deficiency inhibits proliferation by cell cycle control in skeletal muscle cells.</div> </a> <div itemprop="about">Frontiers in physiology</div> <div itemprop="author">Sun J,Su Y,Xu Y,Qin D,He Q,Qiu H,Zhuo J,Li W</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to demonstrate that CD36 was involved in skeletal muscle cell proliferation by cell cycle control, and these findings might facilitate the treatment of obesity-related muscle wasting.</div> <div itemprodp="datePublished">Sat Sep 17 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35149515"> <div itemprop="name">Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Meyer Zu Reckendorf S,Moser D,Blechschmidt A,Joga VN,Sinske D,Hegler J,Deininger S,Catanese A,Vettorazzi S,Antoniadis G,Boeckers T,Knöll B</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to highlight a dual TSG function with PTEN loss impairing physiological neuron function but furthermore underscoring the positive effects of PTEN ablation in axon regeneration also for the PNS.SIGNIFICANCE STATEMENT Tumor suppressor genes (TSGs) restrict cell proliferation and growth.</div> <div itemprodp="datePublished">Wed Mar 23 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35805907"> <div itemprop="name">In Vitro and Ectopic In Vivo Studies toward the Utilization of <i>Rapidly</i> Isolated Human Nasal Chondrocytes for Single-Stage Arthroscopic Cartilage Regeneration Therapy.</div> </a> <div itemprop="about">International journal of molecular sciences</div> <div itemprop="author">Lehoczky G,Trofin RE,Vallmajo-Martin Q,Chawla S,Pelttari K,Mumme M,Haug M,Egloff C,Jakob M,Ehrbar M,Martin I,Barbero A</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to determine the feasibility for a single-stage application of NCs for cartilage regeneration under minimally invasive settings.</div> <div itemprodp="datePublished">Tue Jun 21 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35614224"> <div itemprop="name">ADAR1 masks the cancer immunotherapeutic promise of ZBP1-driven necroptosis.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Zhang T,Yin C,Fedorov A,Qiao L,Bao H,Beknazarov N,Wang S,Gautam A,Williams RM,Crawford JC,Peri S,Studitsky V,Beg AA,Thomas PG,Walkley C,Xu Y,Poptsova M,Herbert A,Balachandran S</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunofluorescence to demonstrate that ADAR1 represses endogenous Z-RNAs and identifies ZBP1-mediated necroptosis as a new determinant of tumour immunogenicity masked by ADAR1.</div> <div itemprodp="datePublished">Wed Jun 01 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35767959"> <div itemprop="name">Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Tholen S,Patel R,Agas A,Kovary KM,Rabiee A,Nicholls HT,Bielczyk-Maczyńska E,Yang W,Kraemer FB,Teruel MN</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate how disrupting circadian glucocorticoid oscillations in mice, akin to stress from jet lag or work-life imbalances, leads to a metabolic state characterized by elevated insulin, low glucose and fatty acids, and adipose tissue expansion, revealing a protective response to chronic stress on metabolic health.</div> <div itemprodp="datePublished">Tue Jun 28 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36381317"> <div itemprop="name">CPSF1 positively regulates NSDHL by alternative polyadenylation and promotes gastric cancer progression.</div> </a> <div itemprop="about">American journal of cancer research</div> <div itemprop="author">Kang W,Yang Y,Chen C,Yu C</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that CPSF1 promotes GC progression, at least in part, by enhancing NSDHL and offered new insights into therapeutic targets for GC.</div> <div itemprodp="datePublished">Thu Nov 17 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36381317"> <div itemprop="name">CPSF1 positively regulates NSDHL by alternative polyadenylation and promotes gastric cancer progression.</div> </a> <div itemprop="about">American journal of cancer research</div> <div itemprop="author">Kang W,Yang Y,Chen C,Yu C</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that CPSF1 promotes GC progression, at least in part, by enhancing NSDHL and offered new insights into therapeutic targets for GC.</div> <div itemprodp="datePublished">Thu Nov 17 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35771632"> <div itemprop="name">CHD1 Promotes Sensitivity to Aurora Kinase Inhibitors by Suppressing Interaction of AURKA with Its Coactivator TPX2.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Li H,Wang Y,Lin K,Venkadakrishnan VB,Bakht M,Shi W,Meng C,Zhang J,Tremble K,Liang X,Song JH,Feng X,Van V,Deng P,Burks JK,Aparicio A,Keyomarsi K,Chen J,Lu Y,Beltran H,Zhao D</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to demonstrate that CHD1 plays an important role in modulating Aurora kinases and drug sensitivities, providing new insights into biomarker-driven therapies targeting Aurora kinases for future clinical studies.</div> <div itemprodp="datePublished">Fri Sep 02 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35892426"> <div itemprop="name">Expression and Prognostic Value of Melanoma-Associated Antigen D2 in Gliomas.</div> </a> <div itemprop="about">Brain sciences</div> <div itemprop="author">Yan J,Li S,Lenahan C,Chen H,Wen J,Huang Q,Jiang Q,Guo F,Deng T,Mo L</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate the mechanism and function of melanoma-associated antigen D2 in glioma.</div> <div itemprodp="datePublished">Tue Jul 26 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35943801"> <div itemprop="name">DHODH is an independent prognostic marker and potent therapeutic target in neuroblastoma.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Olsen TK,Dyberg C,Embaie BT,Alchahin A,Milosevic J,Ding J,Otte J,Tümmler C,Hed Myrberg I,Westerhout EM,Koster J,Versteeg R,Ding HF,Kogner P,Johnsen JI,Sykes DB,Baryawno N</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that DHODH inhibition combined with temozolomide has therapeutic potential in neuroblastoma, and we propose this combination for clinical testing.</div> <div itemprodp="datePublished">Tue Aug 09 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35191836"> <div itemprop="name">Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types.</div> </a> <div itemprop="about">eLife</div> <div itemprop="author">Shekhar K,Whitney IE,Butrus S,Peng YR,Sanes JR</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to study how newly born (postmitotic) mouse retinal ganglion cell (RGC) precursors diversify into ~45 discrete types.</div> <div itemprodp="datePublished">Tue Feb 22 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35867798"> <div itemprop="name">Hypoxia-mediated stabilization of HIF1A in prostatic intraepithelial neoplasia promotes cell plasticity and malignant progression.</div> </a> <div itemprop="about">Science advances</div> <div itemprop="author">Abu El Maaty MA,Terzic J,Keime C,Rovito D,Lutzing R,Yanushko D,Parisotto M,Grelet E,Namer IJ,Lindner V,Laverny G,Metzger D</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to characterize prostatic intraepithelial neoplasia (PIN) progression and demonstrate that HIF1A is a target for PCa prevention and that TGM2 is a promising prognostic biomarker of early relapse after prostatectomy.</div> <div itemprodp="datePublished">Fri Jul 22 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35559665"> <div itemprop="name">BMP signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13-driven tuft cell hyperplasia.</div> </a> <div itemprop="about">Science immunology</div> <div itemprop="author">Lindholm HT,Parmar N,Drurey C,Campillo Poveda M,Vornewald PM,Ostrop J,Díez-Sanchez A,Maizels RM,Oudhoff MJ</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that IL-13 induces the bone morphogenetic protein (BMP) pathway, which acts in a negative feedback loop on immune type 2-driven tuft cell hyperplasia.</div> <div itemprodp="datePublished">Fri May 13 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36528648"> <div itemprop="name">Development of an implantable three-dimensional model of a functional pathogenic multispecies biofilm to study infected wounds.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Cárdenas-Calderón C,Veloso-Giménez V,González T,Wozniak A,García P,Martín SS,Varas JF,Carrasco-Wong I,Vera M,Egaña JT</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to study functional biofilms in physiological conditions in vitro, and their potential effects in health and regeneration in vivo.</div> <div itemprodp="datePublished">Sat Dec 17 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36362338"> <div itemprop="name">Towards an In Vitro 3D Model for Photosynthetic Cancer Treatment: A Study of Microalgae and Tumor Cell Interactions.</div> </a> <div itemprop="about">International journal of molecular sciences</div> <div itemprop="author">Holmes C,Varas J,San Martín S,Egaña JT</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to present a 3D photosynthetic tumor model composed of human melanoma cells and the microalgae Chlamydomonas reinhardtii, both seeded into a collagen scaffold, which allows for the simultaneous study of both cell types.</div> <div itemprodp="datePublished">Fri Nov 04 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35335638"> <div itemprop="name">InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays.</div> </a> <div itemprop="about">Pathogens (Basel, Switzerland)</div> <div itemprop="author">Magalhães AC,Ricardo S,Moreira AC,Nunes M,Tavares M,Pinto RJ,Gomes MS,Pereira L</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to demonstrate that the chip-like organization of the InfectionCMA has several advantages, allowing side-by-side comparisons between diverse cell lines, infection time points, and biomarker expression and cytolocalization evaluation in the same slide.</div> <div itemprodp="datePublished">Thu Mar 03 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35908073"> <div itemprop="name">Maladaptive positive feedback production of ChREBPβ underlies glucotoxic β-cell failure.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Katz LS,Brill G,Zhang P,Kumar A,Baumel-Alterzon S,Honig LB,Gómez-Banoy N,Karakose E,Tanase M,Doridot L,Alvarsson A,Davenport B,Wang P,Lambertini L,Stanley SA,Homann D,Stewart AF,Lo JC,Herman MA,Garcia-Ocaña A,Scott DK</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunoflourescence to investigate if carbohydrate response-element binding protein, whether adaptive or maladaptive, is an important determinant of β-cell fate and a potential target for the preservation of β-cell mass in diabetes.</div> <div itemprodp="datePublished">Sat Jul 30 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36313621"> <div itemprop="name"><i>Npas3</i> regulates stemness maintenance of radial glial cells and neuronal migration in the developing mouse cerebral cortex.</div> </a> <div itemprop="about">Frontiers in cellular neuroscience</div> <div itemprop="author">Liu JW,Li H,Zhang Y</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to demonstrate that Npas3 knockdown profoundly impaired neuronal radial migration and changed the laminar cell fate of the cells detained in the deep cortical layers.</div> <div itemprodp="datePublished">Wed Nov 02 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35861728"> <div itemprop="name">Targeted depletion of uterine glandular Foxa2 induces embryonic diapause in mice.</div> </a> <div itemprop="about">eLife</div> <div itemprop="author">Matsuo M,Yuan J,Kim YS,Dewar A,Fujita H,Dey SK,Sun X</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to show that dormant blastocysts are recovered from these mice on day 8 of pregnancy with persistent expression of uterine Msx1, a gene critical to maintaining the uterine quiescent state, suggesting that these mice enter embryonic diapause.</div> <div itemprodp="datePublished">Thu Jul 21 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35837113"> <div itemprop="name">The Diagnostic Potential of <i>SHOX2</i> and <i>RASSF1A</i> DNA Methylation in Early Lung Adenocarcinoma.</div> </a> <div itemprop="about">Frontiers in oncology</div> <div itemprop="author">Gao H,Yang J,He L,Wang W,Liu Y,Hu Y,Ge M,Ding J,Ye Q</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to conclude that the combined promoter methylation assay for SHOX2 and RASSF1A can be used for screening and diagnosis of early LUAD, with good sensitivity and specificity.</div> <div itemprodp="datePublished">Sat Jul 16 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35085569"> <div itemprop="name">Evaluating Eosinophilic Colitis as a Unique Disease Using Colonic Molecular Profiles: A Multi-Site Study.</div> </a> <div itemprop="about">Gastroenterology</div> <div itemprop="author">Shoda T,Collins MH,Rochman M,Wen T,Caldwell JM,Mack LE,Osswald GA,Besse JA,Haberman Y,Aceves SS,Arva NC,Capocelli KE,Chehade M,Davis CM,Dellon ES,Falk GW,Gonsalves N,Gupta SK,Hirano I,Khoury P,Klion A,Menard-Katcher C,Leung J,Mukkada VA,Putnam PE,Spergel JM,Wechsler JB,Yang GY,Furuta GT,Denson LA,Rothenberg ME</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to establish EoC as a distinct disease compared with other EGIDs and IBD, thereby providing a basis for improving diagnosis and treatment.</div> <div itemprodp="datePublished">Sun May 01 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36428580"> <div itemprop="name">Effect of Collagen Matrix on Doxorubicin Distribution and Cancer Cells' Response to Treatment in 3D Tumor Model.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Druzhkova I,Nikonova E,Ignatova N,Koryakina I,Zyuzin M,Mozherov A,Kozlov D,Krylov D,Kuznetsova D,Lisitsa U,Shcheslavskiy V,Shirshin EA,Zagaynova E,Shirmanova M</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to explore distribution of doxorubicin (DOX) and its effects on cancer cells' metabolism in the presence of collagen with different structures in 3D models.</div> <div itemprodp="datePublished">Tue Nov 08 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/36281643"> <div itemprop="name">Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier.</div> </a> <div itemprop="about">eLife</div> <div itemprop="author">Tran NL,Ferreira LM,Alvarez-Moya B,Buttiglione V,Ferrini B,Zordan P,Monestiroli A,Fagioli C,Bezzecchi E,Scotti GM,Esposito A,Leone R,Gnasso C,Brendolan A,Guidotti LG,Sitia G</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to demonstrate that the continuous infusion of therapeutic doses of interferon-alpha (IFNα) controls CRC invasion by acting on hepatic endothelial cells (HECs).</div> <div itemprodp="datePublished">Tue Oct 25 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33857425"> <div itemprop="name">Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Gangoso E,Southgate B,Bradley L,Rus S,Galvez-Cancino F,McGivern N,Güç E,Kapourani CA,Byron A,Ferguson KM,Alfazema N,Morrison G,Grant V,Blin C,Sou I,Marques-Torrejon MA,Conde L,Parrinello S,Herrero J,Beck S,Brandner S,Brennan PM,Bertone P,Pollard JW,Quezada SA,Sproul D,Frame MC,Serrels A,Pollard SM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry, Immunocytochemistry to conclude that epigenetic immunoediting may drive an acquired immune evasion program in the most aggressive mesenchymal GBM subtype by reshaping the tumor immune microenvironment.</div> <div itemprodp="datePublished">Thu Apr 29 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33857425"> <div itemprop="name">Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Gangoso E,Southgate B,Bradley L,Rus S,Galvez-Cancino F,McGivern N,Güç E,Kapourani CA,Byron A,Ferguson KM,Alfazema N,Morrison G,Grant V,Blin C,Sou I,Marques-Torrejon MA,Conde L,Parrinello S,Herrero J,Beck S,Brandner S,Brennan PM,Bertone P,Pollard JW,Quezada SA,Sproul D,Frame MC,Serrels A,Pollard SM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry, Immunocytochemistry to conclude that epigenetic immunoediting may drive an acquired immune evasion program in the most aggressive mesenchymal GBM subtype by reshaping the tumor immune microenvironment.</div> <div itemprodp="datePublished">Thu Apr 29 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33833454"> <div itemprop="name">Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.</div> </a> <div itemprop="about">Nature genetics</div> <div itemprop="author">Kameneva P,Artemov AV,Kastriti ME,Faure L,Olsen TK,Otte J,Erickson A,Semsch B,Andersson ER,Ratz M,Frisén J,Tischler AS,de Krijger RR,Bouderlique T,Akkuratova N,Vorontsova M,Gusev O,Fried K,Sundström E,Mei S,Kogner P,Baryawno N,Kharchenko PV,Adameyko I</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to examine the transcriptional states of neural crest- and mesoderm-derived lineages differentiating into adrenal glands, kidneys, endothelium and hematopoietic tissue between post-conception weeks 6 and 14 of human development.</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33915078"> <div itemprop="name">Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Breunig M,Merkle J,Wagner M,Melzer MK,Barth TFE,Engleitner T,Krumm J,Wiedenmann S,Cohrs CM,Perkhofer L,Jain G,Krüger J,Hermann PC,Schmid M,Madácsy T,Varga Á,Griger J,Azoitei N,Müller M,Wessely O,Robey PG,Heller S,Dantes Z,Reichert M,Günes C,Bolenz C,Kuhn F,Maléth J,Speier S,Liebau S,Sipos B,Kuster B,Seufferlein T,Rad R,Meier M,Hohwieler M,Kleger A</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that PDLOs enable in vitro and in vivo studies of pancreatic plasticity, dysplasia, and cancer formation from a genetically defined background.</div> <div itemprodp="datePublished">Thu Jun 03 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33932034"> <div itemprop="name">BNIP3 promotes HIF-1α-driven melanoma growth by curbing intracellular iron homeostasis.</div> </a> <div itemprop="about">The EMBO journal</div> <div itemprop="author">Vara-Pérez M,Rossi M,Van den Haute C,Maes H,Sassano ML,Venkataramani V,Michalke B,Romano E,Rillaerts K,Garg AD,Schepkens C,Bosisio FM,Wouters J,Oliveira AI,Vangheluwe P,Annaert W,Swinnen JV,Colet JM,van den Oord JJ,Fendt SM,Mazzone M,Agostinis P</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to unravel an unexpected role of BNIP3 as upstream regulator of the pro-tumorigenic HIF-1α glycolytic program in melanoma cells.</div> <div itemprodp="datePublished">Mon May 17 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33788902"> <div itemprop="name">Intestinal-epithelial LSD1 controls goblet cell maturation and effector responses required for gut immunity to bacterial and helminth infection.</div> </a> <div itemprop="about">PLoS pathogens</div> <div itemprop="author">Parmar N,Burrows K,Vornewald PM,Lindholm HT,Zwiggelaar RT,Díez-Sánchez A,Martín-Alonso M,Fosslie M,Vallance BA,Dahl JA,Zaph C,Oudhoff MJ</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show intestinal-epithelial epigenetic regulation by LSD1 as a critical element in host protection from infection.</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34180969"> <div itemprop="name">EHF is essential for epidermal and colonic epithelial homeostasis, and suppresses Apc-initiated colonic tumorigenesis.</div> </a> <div itemprop="about">Development (Cambridge, England)</div> <div itemprop="author">Reehorst CM,Nightingale R,Luk IY,Jenkins L,Koentgen F,Williams DS,Darido C,Tan F,Anderton H,Chopin M,Schoffer K,Eissmann MF,Buchert M,Mouradov D,Sieber OM,Ernst M,Dhillon AS,Mariadason JM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate the role of Ets homologous factor in development and epithelial homeostasis.</div> <div itemprodp="datePublished">Tue Jun 15 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33649104"> <div itemprop="name">Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Wang Y,Pandey RN,Roychoudhury K,Milewski D,Kalin TV,Szabo S,Pressey JG,Hegde RS</div> <div itemprop="description">MA5-14520 was used in Functional Assay to investigate molecular and cellular mechanisms through which EYA3 might promote Ewing sarcoma tumor growth and to determine whether the EYA3 tyrosine phosphatase activity represents a viable therapeutic target.</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33649104"> <div itemprop="name">Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Wang Y,Pandey RN,Roychoudhury K,Milewski D,Kalin TV,Szabo S,Pressey JG,Hegde RS</div> <div itemprop="description">MA5-14520 was used in Functional Assay to investigate molecular and cellular mechanisms through which EYA3 might promote Ewing sarcoma tumor growth and to determine whether the EYA3 tyrosine phosphatase activity represents a viable therapeutic target.</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35005034"> <div itemprop="name">Knockdown of lncRNA CCAT1 Inhibits the Progression of Colorectal Cancer via hsa-miR-4679 Mediating the Downregulation of GNG10.</div> </a> <div itemprop="about">Journal of immunology research</div> <div itemprop="author">Wang N,Li J,He J,Jing YG,Zhao WD,Yu WJ,Wang J</div> <div itemprop="description">MA5-14520 was used in Western Blot, Immunohistochemistry to reveal that lncRNA CCAT1 facilitated colorectal cancer progression via the hsa-miR-4679/GNG10 axis and provided new potential therapeutic targets for colorectal cancer.</div> <div itemprodp="datePublished">Fri Feb 24 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/35005034"> <div itemprop="name">Knockdown of lncRNA CCAT1 Inhibits the Progression of Colorectal Cancer via hsa-miR-4679 Mediating the Downregulation of GNG10.</div> </a> <div itemprop="about">Journal of immunology research</div> <div itemprop="author">Wang N,Li J,He J,Jing YG,Zhao WD,Yu WJ,Wang J</div> <div itemprop="description">MA5-14520 was used in Western Blot, Immunohistochemistry to reveal that lncRNA CCAT1 facilitated colorectal cancer progression via the hsa-miR-4679/GNG10 axis and provided new potential therapeutic targets for colorectal cancer.</div> <div itemprodp="datePublished">Fri Feb 24 00:00:00 EST 2023</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34093025"> <div itemprop="name">Acetone Extract of <i>Cornus officinalis</i> Leaves Exerts Anti-Melanoma Effects via Inhibiting STAT3 Signaling.</div> </a> <div itemprop="about">OncoTargets and therapy</div> <div itemprop="author">Xu R,Zeng M,Wu Y,Wang S,Zhang B,Zhang J,Kan Y,Li B,Cao B,Zheng X,Feng W</div> <div itemprop="description">MA5-14520 was used in Western Blot to investigate the intervention and mechanism of 50% acetone extract of C. officinalis leaves (SZYY) on melanoma xenografts.</div> <div itemprodp="datePublished">Sat Apr 23 00:00:00 EDT 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33550377"> <div itemprop="name">Evidence and manipulation of O-GlcNAcylation in granulosa cells of bovine antral follicles†.</div> </a> <div itemprop="about">Biology of reproduction</div> <div itemprop="author">Maucieri AM,Townson DH</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to determine O-GlcNAcylation in GCs and its effects on GC proliferation.</div> <div itemprodp="datePublished">Thu Apr 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33416154"> <div itemprop="name">Exosomes derived from retinoblastoma cells enhance tumour deterioration by infiltrating the microenvironment.</div> </a> <div itemprop="about">Oncology reports</div> <div itemprop="author">Chen S,Chen X,Qiu J,Chen P,Han X,Wu Y,Zhuang J,Yang M,Wu C,Wu N,Yang Y,Ge J,Yu K,Zhuang J</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to reveal the role of exosomes (EXOs) from retinoblastoma cells in tumour development.</div> <div itemprodp="datePublished">Fri Jan 01 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33822400"> <div itemprop="name">Inhibition of STAT3 prevents bone metastatic progression of prostate cancer in vivo.</div> </a> <div itemprop="about">The Prostate</div> <div itemprop="author">Thulin MH,Määttä J,Linder A,Sterbova S,Ohlsson C,Damber JE,Widmark A,Persson E</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to suggest STAT3 as a candidate for molecular targeted therapies of skeletal metastatic disease.</div> <div itemprodp="datePublished">Tue Jun 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33531677"> <div itemprop="name">Sexual dimorphisms in brain gene expression in the growth-restricted guinea pig can be modulated with intra-placental therapy.</div> </a> <div itemprop="about">Pediatric research</div> <div itemprop="author">Wilson RL,Stephens KK,Lampe K,Jones HN</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to study morphology and messenger RNA expression in fetal growth-restricted tissues at midpregnancy in fetal guinea pigs.</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33922332"> <div itemprop="name">Histological and Immunohistochemical Characterization of Vomeronasal Organ Aging in Mice.</div> </a> <div itemprop="about">Animals : an open access journal from MDPI</div> <div itemprop="author">Mechin V,Pageat P,Teruel E,Asproni P</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to study the role of ageing in neuronal degeneration using histological and immunohistological analysis in mice.</div> <div itemprodp="datePublished">Thu Apr 22 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33619909"> <div itemprop="name">STRADA-mutant human cortical organoids model megalencephaly and exhibit delayed neuronal differentiation.</div> </a> <div itemprop="about">Developmental neurobiology</div> <div itemprop="author">Dang LT,Vaid S,Lin G,Swaminathan P,Safran J,Loughman A,Lee M,Glenn T,Majolo F,Crino PB,Parent JM</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunoflourescence to study the effect of mechanistic target of rapamycin hyperactivity on early stages of cortical development.</div> <div itemprodp="datePublished">Thu Jul 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33041094"> <div itemprop="name">Insulin-like growth factor 1 promotes the extension of Tracheal Epithelium in an in Vitro Tracheal organ culture model.</div> </a> <div itemprop="about">Auris, nasus, larynx</div> <div itemprop="author">Kishimoto I,Ohnishi H,Yamahara K,Nakagawa T,Yamashita M,Omori K,Yamamoto N</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that topical insulin-like growth factor 1 treatment promoted the extension of tracheal epithelium, suggesting the potential utility of insulin-like growth factor 1 in aiding rapid tracheal epithelialization in patients requiring tracheal reconstruction using tissue-engineered tracheas.</div> <div itemprodp="datePublished">Tue Jun 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34142050"> <div itemprop="name">Molecular docking-aided identification of small molecule inhibitors targeting β-catenin-TCF4 interaction.</div> </a> <div itemprop="about">iScience</div> <div itemprop="author">Low JL,Du W,Gocha T,Oguz G,Zhang X,Chen MW,Masirevic S,Yim DGR,Tan IBH,Ramasamy A,Fan H,DasGupta R</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to to report a molecular docking-based approach to identify small molecules that can target the β-catenin (β-cat)-TCF4 protein-protein interaction (PPI), a key effector complex for nuclear Wnt signaling activity.</div> <div itemprodp="datePublished">Fri Jun 25 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33958986"> <div itemprop="name">DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice.</div> </a> <div itemprop="about">Frontiers in neuroscience</div> <div itemprop="author">Chen X,Huang NX,Cheng YJ,Cai QY,Tian YP,Chen XS,Xiao L</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to provide new insights into the possibility that precise modulation of DNA methylation status in oligodendroglia could be beneficial for the white matter pathology in schizophrenia.</div> <div itemprodp="datePublished">Sat May 08 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33691110"> <div itemprop="name">Functional cooperation between co-amplified genes promotes aggressive phenotypes of HER2-positive breast cancer.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Yang Y,Leonard M,Luo Z,Yeo S,Bick G,Hao M,Cai C,Charif M,Wang J,Guan JL,Lower EE,Zhang X</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to support a functional cooperation between MED1 and HER2 co-amplified genes in HER2+ mammary tumorigenesis with potential use as therapeutic targets for the treatment of HER2+ breast cancers.</div> <div itemprodp="datePublished">Tue Mar 09 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34275297"> <div itemprop="name">Rapid Prototyping of Multilayer Microphysiological Systems.</div> </a> <div itemprop="about">ACS biomaterials science & engineering</div> <div itemprop="author">Hosic S,Bindas AJ,Puzan ML,Lake W,Soucy JR,Zhou F,Koppes RA,Breault DT,Murthy SK,Koppes AN</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to present a compelling fabrication technique for developing organs-on-chips of various geometries to study multicellular tissues.</div> <div itemprodp="datePublished">Mon Jul 12 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33583913"> <div itemprop="name">Immunohistochemical evaluation of hepatic progenitor cells in different types of feline liver diseases.</div> </a> <div itemprop="about">The Journal of veterinary medical science</div> <div itemprop="author">Abou Monsef Y,Kutsal O</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to indicate the major role played by hepatic progenitor cells in regeneration of the feline liver.</div> <div itemprodp="datePublished">Fri Apr 09 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33732255"> <div itemprop="name">The SWI/SNF-Related, Matrix Associated, Actin-Dependent Regulator of Chromatin A4 Core Complex Represses Respiratory Syncytial Virus-Induced Syncytia Formation and Subepithelial Myofibroblast Transition.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Xu X,Qiao D,Dong C,Mann M,Garofalo RP,Keles S,Brasier AR</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunoflourescence to examine the epigenetic role of the SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin A4 in the epithelial response to RSV infection.</div> <div itemprodp="datePublished">Thu Sep 16 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33985378"> <div itemprop="name">Expression of Grainyhead-like 2 in the Process of Ductal Development of Mouse Mammary Gland.</div> </a> <div itemprop="about">The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society</div> <div itemprop="author">Matsuoka S,Suzuki H,Kato C,Kamikawa-Tokai M,Kamikawa A,Okamatsu-Ogura Y,Kimura K</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that Grhl2 expressed in the luminal epithelial and myoepithelial cells from the early phase of ductal development, controlling the expression of cell adhesion molecules to establish functional ducts.</div> <div itemprodp="datePublished">Tue Jun 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33802342"> <div itemprop="name">Effect of Reducing Ataxia-Telangiectasia Mutated (ATM) in Experimental Autosomal Dominant Polycystic Kidney Disease.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Zhang JQJ,Saravanabavan S,Rangan GK</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to conclude that despite short-term effects on reducing renal cell proliferation, chronic progression was not altered by reducing ATM in vivo.</div> <div itemprodp="datePublished">Wed Mar 03 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33819917"> <div itemprop="name">miR-224 aggravates cancer-associated fibroblast-induced progression of non-small cell lung cancer by modulating a positive loop of the SIRT3/AMPK/mTOR/HIF-1α axis.</div> </a> <div itemprop="about">Aging</div> <div itemprop="author">Zhang J,Han L,Yu J,Li H,Li Q</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that both Sirt1 overexpression and HIF-1α inhibition repressed miR-224 levels and miR-224-mediated promotive effects in NSCLC.</div> <div itemprodp="datePublished">Sun Apr 04 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34795242"> <div itemprop="name">Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Martín-Alonso M,Iqbal S,Vornewald PM,Lindholm HT,Damen MJ,Martínez F,Hoel S,Díez-Sánchez A,Altelaar M,Katajisto P,Arroyo AG,Oudhoff MJ</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to identify an important signaling axis that establishes a role for smooth muscle cells as modulators of intestinal epithelial regeneration and the intestinal stem cell niche.</div> <div itemprodp="datePublished">Thu Nov 18 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33469141"> <div itemprop="name">TNFα promotes oral cancer growth, pain, and Schwann cell activation.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Salvo E,Tu NH,Scheff NN,Dubeykovskaya ZA,Chavan SA,Aouizerat BE,Ye Y</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to suggest that TNFα promotes cancer proliferation, progression, and nociception at least partially by activating Schwann cells. Inhibiting TNFα or Schwann cell activation might serve as therapeutic approaches for the treatment of oral cancer and associated pain.</div> <div itemprodp="datePublished">Tue Jan 19 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34485937"> <div itemprop="name">Generation and functional characterization of murine mammary organoids.</div> </a> <div itemprop="about">STAR protocols</div> <div itemprop="author">Yip HYK,Papa A</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to describe step-by-step experimental procedures for the successful establishment of murine mammary organoid lines isolated from mammary glands or mammary tumors driven by mutations in components of the PI3K pathway.</div> <div itemprodp="datePublished">Fri Sep 17 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34053165"> <div itemprop="name">Role of Adiponectin-Notch pathway in cognitive dysfunction associated with depression and in the therapeutic effect of physical exercise.</div> </a> <div itemprop="about">Aging cell</div> <div itemprop="author">You J,Sun L,Wang J,Sun F,Wang W,Wang D,Fan X,Liu D,Xu Z,Qiu C,Chen J,Yan H,Liu B</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that Adiponectin-Notch pathway is involved in the pathogenesis of cognitive dysfunction associated with depression, but also contributes to the therapeutic effect of physical exercise.</div> <div itemprodp="datePublished">Tue Jun 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33931446"> <div itemprop="name">Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance.</div> </a> <div itemprop="about">Science advances</div> <div itemprop="author">Ma W,Gil HJ,Liu X,Diebold LP,Morgan MA,Oxendine-Burns MJ,Gao P,Chandel NS,Oliver G</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to indicate that by sensing the LEC differentiation status and microenvironmental metabolic conditions, mitochondrial complex III regulates the critical Prox1-Vegfr3 feedback loop and, therefore, LEC fate specification and maintenance.</div> <div itemprodp="datePublished">Thu Apr 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34769334"> <div itemprop="name">Selenoprotein DIO2 Is a Regulator of Mitochondrial Function, Morphology and UPRmt in Human Cardiomyocytes.</div> </a> <div itemprop="about">International journal of molecular sciences</div> <div itemprop="author">Bomer N,Pavez-Giani MG,Deiman FE,Linders AN,Hoes MF,Baierl CLJ,Oberdorf-Maass SU,de Boer RA,Silljé HHW,Berezikov E,Simonides WS,Westenbrink BD,van der Meer P</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to suggest a key position of human DIO2 as a regulator of mitochondrial function in human cardiomyocytes.</div> <div itemprodp="datePublished">Tue Nov 02 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33596850"> <div itemprop="name">Following cytotoxic nanoconjugates from injection to halting the cell cycle machinery and its therapeutic implications in oral cancer.</div> </a> <div itemprop="about">BMC cancer</div> <div itemprop="author">Abdel Hamid HM,Darwish ZE,Elsheikh SM,Mourad GM,Donia HM,Afifi MM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to indicate that the cellular biological events do not predict the outcome seen in our in vivo model.</div> <div itemprodp="datePublished">Wed Feb 17 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34651140"> <div itemprop="name">Peroxisomal L-bifunctional protein (EHHADH) deficiency causes male-specific kidney hypertrophy and proximal tubular injury in mice.</div> </a> <div itemprop="about">Kidney360</div> <div itemprop="author">Ranea-Robles P,Portman K,Bender A,Lee K,He JC,Mulholland DJ,Argmann C,Houten SM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to assess the role of androgens in the kidney phenotype of Ehhadh KO mice.</div> <div itemprodp="datePublished">Wed Sep 01 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34965417"> <div itemprop="name">Human iPSC-derived fallopian tube organoids with BRCA1 mutation recapitulate early-stage carcinogenesis.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Yucer N,Ahdoot R,Workman MJ,Laperle AH,Recouvreux MS,Kurowski K,Naboulsi DJ,Liang V,Qu Y,Plummer JT,Gayther SA,Orsulic S,Karlan BY,Svendsen CN</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to generate induced pluripotent stem cells (iPSCs) from healthy individuals and young ovarian cancer patients with germline pathogenic BRCA1 mutations (BRCA1mut).</div> <div itemprodp="datePublished">Tue Dec 28 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33803359"> <div itemprop="name">Integrin α10-Antibodies Reduce Glioblastoma Tumor Growth and Cell Migration.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Masoumi KC,Huang X,Sime W,Mirkov A,Munksgaard Thorén M,Massoumi R,Lundgren-Åkerlund E</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that function-blocking antibody targeting integrin α10β1 is a promising therapeutic strategy for the treatment of glioblastoma.</div> <div itemprodp="datePublished">Tue Mar 09 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33807449"> <div itemprop="name">High-Grade B-Cell Lymphoma (HGBL) with <i>MYC</i> and <i>BCL2</i> and/or <i>BCL6</i> Rearrangements Is Predominantly BCL6-Rearranged and BCL6-Expressing in Taiwan.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Tsai CC,Su YC,Bamodu OA,Chen BJ,Tsai WC,Cheng WH,Lee CH,Hsieh SM,Liu ML,Fang CL,Lin HT,Chen CL,Yeh CT,Lee WH,Ho CL,Lai SW,Tzeng HE,Hsieh YY,Chang CL,Zheng YM,Liu HW,Yen Y,Whang-Peng J,Chao TY</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate the epidemiological and clinical peculiarities of BCL2 and BCL6 rearrangement in patients with high grade B-cell lymphoma (HGBL) from Taiwan, compared with data from Western countries.</div> <div itemprodp="datePublished">Wed Mar 31 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34566896"> <div itemprop="name">Gene Signatures of NEUROGENIN3+ Endocrine Progenitor Cells in the Human Pancreas.</div> </a> <div itemprop="about">Frontiers in endocrinology</div> <div itemprop="author">Yong HJ,Xie G,Liu C,Wang W,Naji A,Irianto J,Wang YJ</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to test the hypothesis that single-cell RNA-seq enables in-depth exploration of the rare NEUROG3+ cells directly in humans.</div> <div itemprodp="datePublished">Tue Feb 15 00:00:00 EST 2022</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33664254"> <div itemprop="name">Loss of retinoic acid receptor-related receptor alpha (Rorα) promotes the progression of UV-induced cSCC.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Zhang G,Yan G,Fu Z,Wu Y,Wu F,Zheng Z,Fang S,Gao Y,Bao X,Liu Y,Wang X,Zhu S</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that Rorα would serve as a potential novel target for cSCC, which will facilitate the treatment of cSCC in the future.</div> <div itemprodp="datePublished">Thu Mar 04 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/34158865"> <div itemprop="name">Arginine starvation elicits chromatin leakage and cGAS-STING activation via epigenetic silencing of metabolic and DNA-repair genes.</div> </a> <div itemprop="about">Theranostics</div> <div itemprop="author">Hsu SC,Chen CL,Cheng ML,Chu CY,Changou CA,Yu YL,Yeh SD,Kuo TC,Kuo CC,Chuu CP,Li CF,Wang LH,Chen HW,Yen Y,Ann DK,Wang HJ,Kung HJ</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate the underlying mechanisms by which arginine starvation-induced cell death and to develop a dietary arginine-restriction xenograft model to study the in vivo effects.</div> <div itemprodp="datePublished">Wed Jul 28 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33503423"> <div itemprop="name">A constant pool of Lgr5<sup>+</sup> intestinal stem cells is required for intestinal homeostasis.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Tan SH,Phuah P,Tan LT,Yada S,Goh J,Tomaz LB,Chua M,Wong E,Lee B,Barker N</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to study relevance of diphtheria toxin receptors in intestinal epithelial integrity and turnover in vivo.</div> <div itemprodp="datePublished">Tue Jan 26 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33859191"> <div itemprop="name">SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Wang X,Zhang H,Sapio R,Yang J,Wong J,Zhang X,Guo JY,Pine S,Van Remmen H,Li H,White E,Liu C,Kiledjian M,Pestov DG,Steven Zheng XF</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to describe the generation of an inducible Sod1 knockout in KRAS-driven NSCLC mouse model.</div> <div itemprodp="datePublished">Thu Apr 15 00:00:00 EDT 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32025032"> <div itemprop="name">AQP5 enriches for stem cells and cancer origins in the distal stomach.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Tan SH,Swathi Y,Tan S,Goh J,Seishima R,Murakami K,Oshima M,Tsuji T,Phuah P,Tan LT,Wong E,Fatehullah A,Sheng T,Ho SWT,Grabsch HI,Srivastava S,Teh M,Denil SLIJ,Mustafah S,Tan P,Shabbir A,So J,Yeoh KG,Barker N</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to show that stem cells within the AQP5+ compartment are a source of WNT-driven, invasive gastric cancer in vivo, using newly generated Aqp5-creERT2 mouse models.</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32059779"> <div itemprop="name">Single-Cell Transcriptome Atlas of Murine Endothelial Cells.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Kalucka J,de Rooij LPMH,Goveia J,Rohlenova K,Dumas SJ,Meta E,Conchinha NV,Taverna F,Teuwen LA,Veys K,García-Caballero M,Khan S,Geldhof V,Sokol L,Chen R,Treps L,Borri M,de Zeeuw P,Dubois C,Karakach TK,Falkenberg KD,Parys M,Yin X,Vinckier S,Du Y,Fenton RA,Schoonjans L,Dewerchin M,Eelen G,Thienpont B,Lin L,Bolund L,Li X,Luo Y,Carmeliet P</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to create a detailed atlas of >32,000 single-endothelial cell transcriptomes.</div> <div itemprodp="datePublished">Thu Feb 20 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31941709"> <div itemprop="name">MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.</div> </a> <div itemprop="about">Cancer discovery</div> <div itemprop="author">Sodir NM,Kortlever RM,Barthet VJA,Campos T,Pellegrinet L,Kupczak S,Anastasiou P,Swigart LB,Soucek L,Arends MJ,Littlewood TD,Evan GI</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that this Myc-driven PDAC switch is completely and immediately reversible: Myc deactivation/inhibition triggers meticulous disassembly of advanced PDAC tumor and stroma and concomitant death of tumor cells.</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31857074"> <div itemprop="name">Oncogenic Mutations in Armadillo Repeats 5 and 6 of β-Catenin Reduce Binding to APC, Increasing Signaling and Transcription of Target Genes.</div> </a> <div itemprop="about">Gastroenterology</div> <div itemprop="author">Liu P,Liang B,Liu M,Lebbink JHG,Li S,Qian M,Lavrijsen M,Peppelenbosch MP,Chen X,Smits R</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate the mechanisms by which these substitutions increase signaling and the effects on liver carcinogenesis in mice.</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31844326"> <div itemprop="name">An intrinsic role of IL-33 in T<sub>reg</sub> cell-mediated tumor immunoevasion.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Hatzioannou A,Banos A,Sakelaropoulos T,Fedonidis C,Vidali MS,Köhne M,Händler K,Boon L,Henriques A,Koliaraki V,Georgiadis P,Zoidakis J,Termentzi A,Beyer M,Chavakis T,Boumpas D,Tsirigos A,Verginis P</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to identify a cell-intrinsic role of the alarmin interleukin (IL)-33 in the functional stability of Treg cells.</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32510550"> <div itemprop="name">Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer.</div> </a> <div itemprop="about">The Journal of experimental medicine</div> <div itemprop="author">Recouvreux MV,Moldenhauer MR,Galenkamp KMO,Jung M,James B,Zhang Y,Lowy A,Bagchi A,Commisso C</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that nutrient stress caused by glutamine deprivation leads to the induction of epithelial-mesenchymal transition (EMT) in pancreatic ductal adenocarcinoma (PDAC) cells.</div> <div itemprodp="datePublished">Mon Sep 07 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31462148"> <div itemprop="name">Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease.</div> </a> <div itemprop="about">Autophagy</div> <div itemprop="author">Yazdankhah M,Shang P,Ghosh S,Bhutto IA,Stepicheva N,Grebe R,Hose S,Weiss J,Luo T,Mishra S,Riazuddin SA,Ghosh A,Handa JT,Lutty GA,Zigler JS,Sinha D</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate in vivo that gefitinib (EGFR inhibitor) can rescue the PFV phenotype in Nuc1 and may serve as a novel therapy for PFV disease by modulating the EGFR-MTORC1-autophagy pathway.</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33047378"> <div itemprop="name">Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.</div> </a> <div itemprop="about">Cell proliferation</div> <div itemprop="author">Lan C,Cao N,Chen C,Qu S,Fan C,Luo H,Zeng A,Yu C,Xue Y,Ren H,Li L,Wang H,Jose PA,Xu Z,Zeng C</div> <div itemprop="description">MA5-14520 was used in Western Blotting to uncover a role of circulating progesterone withdrawal as a novel mechanism for the postnatal loss of mammalian cardiac regenerative potential.</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31833591"> <div itemprop="name">Deletion of astrocytic BMAL1 results in metabolic imbalance and shorter lifespan in mice.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Barca-Mayo O,Boender AJ,Armirotti A,De Pietri Tonelli D</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Frozen) to study how astrocyte-specific deletion of clock gene Bmal1 contributes to metabolic dysfunction and early death.</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32853024"> <div itemprop="name">Immune Modulation to Improve Survival of Viral Pneumonia in Mice.</div> </a> <div itemprop="about">American journal of respiratory cell and molecular biology</div> <div itemprop="author">Wali S,Flores JR,Jaramillo AM,Goldblatt DL,Pantaleón García J,Tuvim MJ,Dickey BF,Evans SE</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry to validate strategies for immune modulation in a preclinical model of viral pneumonia and determine their mechanisms.</div> <div itemprodp="datePublished">Tue Dec 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32895290"> <div itemprop="name">RAB6 GTPase regulates mammary secretory function by controlling the activation of STAT5.</div> </a> <div itemprop="about">Development (Cambridge, England)</div> <div itemprop="author">Cayre S,Faraldo MM,Bardin S,Miserey-Lenkei S,Deugnier MA,Goud B</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to reveal a crucial role for RAB6A/A' in the lactogenic function of the mammary gland and suggest that the trafficking pathways controlled by RAB6A/A' depend on cell-type specialization and tissue context.</div> <div itemprodp="datePublished">Thu Oct 08 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32860300"> <div itemprop="name">UDP-glucuronosyltransferase polymorphisms affect diethylnitrosamine-induced carcinogenesis in humanized transgenic mice.</div> </a> <div itemprop="about">Cancer science</div> <div itemprop="author">Landerer S,Kalthoff S,Paulusch S,Strassburg CP</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to examine the direct effect of common UGT1A polymorphisms (SNPs) on HCC development and outcome in a diethylnitrosamine (DEN)-induced mouse model.</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32198139"> <div itemprop="name">Targeting Fatty Acid Oxidation to Promote Anoikis and Inhibit Ovarian Cancer Progression.</div> </a> <div itemprop="about">Molecular cancer research : MCR</div> <div itemprop="author">Sawyer BT,Qamar L,Yamamoto TM,McMellen A,Watson ZL,Richer JK,Behbakht K,Schlaepfer IR,Bitler BG</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to examine the contribution of fatty acid oxidation in supporting anoikis resistance using HGSOC cell lines.</div> <div itemprodp="datePublished">Wed Jul 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31897489"> <div itemprop="name">The sialyltransferase ST6GAL1 protects against radiation-induced gastrointestinal damage.</div> </a> <div itemprop="about">Glycobiology</div> <div itemprop="author">Punch PR,Irons EE,Manhardt CT,Marathe H,Lau JTY</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate the contribution of ST6GAL1 to susceptibility to total body irradiation in vivo.</div> <div itemprodp="datePublished">Mon Jul 20 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32275903"> <div itemprop="name">Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Zhou Y,Xu M,Liu P,Liang B,Qian M,Wang H,Song X,Nyshadham P,Che L,Calvisi DF,Li F,Lin S,Chen X</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to indicate that mTORC2 signaling effectively regulates liver regeneration by inducing oval cell proliferation.</div> <div itemprodp="datePublished">Wed Jul 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32323739"> <div itemprop="name">The secretome of human dental pulp stem cells protects myoblasts from hypoxia‑induced injury via the Wnt/β‑catenin pathway.</div> </a> <div itemprop="about">International journal of molecular medicine</div> <div itemprop="author">Zhang W,Yu L,Han X,Pan J,Deng J,Zhu L,Lu Y,Huang W,Liu S,Li Q,Liu Y</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunoflourescence to demonstrate that C2C12 myoblast coculture with human dental pulp stem cells (hDPSCs) attenuated CoCl2-induced hypoxic injury compared with C2C12 alone.</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32175801"> <div itemprop="name">Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis.</div> </a> <div itemprop="about">Epigenetics</div> <div itemprop="author">Shue YT,Lee KT,Walters BW,Ong HB,Silvaraju S,Lam WJ,Lim CY</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to investigate the dynamics of 13 key histone marks in epidermal cells at three distinct stages of embryonic skin development and identified significant changes that corresponded with the maturation of the proliferative basal epidermal cells and terminally differentiated cells in the stratified layers.</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32711367"> <div itemprop="name">Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors.</div> </a> <div itemprop="about">Translational oncology</div> <div itemprop="author">Wang Y,Wozniak A,Wellens J,Gebreyohannes YK,Guillén MJ,Avilés PM,Debiec-Rychter M,Sciot R,Schöffski P</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to evaluate a tubulin inhibitor, plocabulin, in patient-derived xenograft (PDX) models of GIST, a disease generally considered to be resistant to cytotoxic agents.</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31794893"> <div itemprop="name">Loss of Setd4 delays radiation-induced thymic lymphoma in mice.</div> </a> <div itemprop="about">DNA repair</div> <div itemprop="author">Feng X,Lu H,Yue J,Schneider N,Liu J,Denzin LK,Chan CS,De S,Shen Z</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to report that conditional Setd4 deletion in adult mice significantly extended the survival of radiation-induced T-lymphoma.</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31894330"> <div itemprop="name">Silencing of long‑chain non‑coding RNA GAS5 in osteoarthritic chondrocytes is mediated by targeting the miR‑34a/Bcl‑2 axis.</div> </a> <div itemprop="about">Molecular medicine reports</div> <div itemprop="author">Ji Q,Qiao X,Liu Y,Wang D,Yan J</div> <div itemprop="description">MA5-14520 was used in Western Blot to indicate that GAS5 participated in the development of OA by regulating the biological behavior of chondrocytes via the miR‚34a/Bcl‚2 axis.</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32169553"> <div itemprop="name">Optic vesicle morphogenesis requires primary cilia.</div> </a> <div itemprop="about">Developmental biology</div> <div itemprop="author">Fiore L,Takata N,Acosta S,Ma W,Pandit T,Oxendine M,Oliver G</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate the role of primary cilia during the morphogenetic movements required for the formation of the eye.</div> <div itemprodp="datePublished">Mon Jun 15 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32724368"> <div itemprop="name">Long non-coding RNA RFPL3S is a novel prognostic biomarker in lung cancer.</div> </a> <div itemprop="about">Oncology letters</div> <div itemprop="author">Liu Z,Ning Z,Lu H,Cao T,Zhou F,Ye X,Chen C</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to investigate the expression pattern of RFPL3 antisense (RFPL3S) and its associations with clinicopathological characteristics in patients with lung cancer.</div> <div itemprodp="datePublished">Sat Aug 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32290286"> <div itemprop="name">A Novel Approach to Deliver Therapeutic Extracellular Vesicles Directly into the Mouse Kidney via Its Arterial Blood Supply.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Ullah M,Liu DD,Rai S,Razavi M,Choi J,Wang J,Concepcion W,Thakor AS</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to develop in mice a reproducible microsurgical technique for the delivery of therapeutics directly into each kidney, via its arterial blood supply.</div> <div itemprodp="datePublished">Fri Apr 10 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32726619"> <div itemprop="name">Proximal Tubule mTORC1 Is a Central Player in the Pathophysiology of Diabetic Nephropathy and Its Correction by SGLT2 Inhibitors.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Kogot-Levin A,Hinden L,Riahi Y,Israeli T,Tirosh B,Cerasi E,Mizrachi EB,Tam J,Mosenzon O,Leibowitz G</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunoflourescence to study mTORC1 in the context of the pathogenesis of diabetic nephropathy.</div> <div itemprodp="datePublished">Tue Jul 28 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32402277"> <div itemprop="name">Nutrient-Driven O-GlcNAcylation Controls DNA Damage Repair Signaling and Stem/Progenitor Cell Homeostasis.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Na HJ,Akan I,Abramowitz LK,Hanover JA</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to reveal a conserved mechanistic link among O-GlcNAc cycling, stem cell self-renewal, and DDR with profound implications for stem-cell-derived diseases including cancer.</div> <div itemprodp="datePublished">Tue May 12 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33371498"> <div itemprop="name">Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Thomas MJ,Major E,Benedek A,Horváth I,Máthé D,Bergmann R,Szász AM,Krenács T,Benyó Z</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to evaluate the potential of mEHT, inducing local hyperthermia, in the treatment of pulmonary metastatic melanoma.</div> <div itemprodp="datePublished">Mon Dec 21 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33033234"> <div itemprop="name">AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Yao CD,Haensel D,Gaddam S,Patel T,Atwood SX,Sarin KY,Whitson RJ,McKellar S,Shankar G,Aasi S,Rieger K,Oro AE</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to identify three prognostic surface markers (LYPD3, TACSTD2, and LY6D) which correlate with nuclear myocardin-related transcription factor(nMRTF) and resistance to Smoothened(SMO) inhibitors, using single-cell RNA-sequencing of patient tumours.</div> <div itemprodp="datePublished">Thu Oct 08 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32163428"> <div itemprop="name">IODVA1, a guanidinobenzimidazole derivative, targets Rac activity and Ras-driven cancer models.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Gasilina A,Premnauth G,Gurjar P,Biesiada J,Hegde S,Milewski D,Ma G,Kalin TV,Merino E,Meller J,Seibel W,Cancelas JA,Vinnedge LP,Nassar NN</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to report the synthesis and preliminary characterization of IODVA1, a potent small molecule that is active in xenograft mouse models of Ras-driven lung and breast cancers.</div> <div itemprodp="datePublished">Mon Jul 20 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32917713"> <div itemprop="name">LSD1 represses a neonatal/reparative gene program in adult intestinal epithelium.</div> </a> <div itemprop="about">Science advances</div> <div itemprop="author">Zwiggelaar RT,Lindholm HT,Fosslie M,Terndrup Pedersen M,Ohta Y,Díez-Sánchez A,Martín-Alonso M,Ostrop J,Matano M,Parmar N,Kvaløy E,Spanjers RR,Nazmi K,Rye M,Drabløs F,Arrowsmith C,Arne Dahl J,Jensen KB,Sato T,Oudhoff MJ</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to identify regulators of neonatal intestinal epithelial development by testing a small library of epigenetic modifier inhibitors in Paneth cell-skewed organoid cultures.</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32010784"> <div itemprop="name">Novel CD11b<sup>+</sup>Gr-1<sup>+</sup>Sca-1<sup>+</sup> myeloid cells drive mortality in bacterial infection.</div> </a> <div itemprop="about">Science advances</div> <div itemprop="author">Park MY,Kim HS,Lee HY,Zabel BA,Bae YS</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry to find a previously unidentified pathogenic CD11b+Gr-1+ myeloid cell population that expresses stem cell antigen-1 (Sca-1) induced upon experimental infection with Staphylococcus aureus.</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32554855"> <div itemprop="name">Long-term PM<sub>2.5</sub> exposure increases the risk of non-small cell lung cancer (NSCLC) progression by enhancing interleukin-17a (IL-17a)-regulated proliferation and metastasis.</div> </a> <div itemprop="about">Aging</div> <div itemprop="author">Chao X,Yi L,Lan LL,Wei HY,Wei D</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to explore the role of PM2.5 in the etiology of NSCLC.</div> <div itemprodp="datePublished">Thu Jun 18 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33575256"> <div itemprop="name">A Semi-automated Organoid Screening Method Demonstrates Epigenetic Control of Intestinal Epithelial Differentiation.</div> </a> <div itemprop="about">Frontiers in cell and developmental biology</div> <div itemprop="author">Ostrop J,Zwiggelaar RT,Terndrup Pedersen M,Gerbe F,Bösl K,Lindholm HT,Díez-Sánchez A,Parmar N,Radetzki S,von Kries JP,Jay P,Jensen KB,Arrowsmith C,Oudhoff MJ</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to develop a semi-automated organoid screening method, to be applied to a library of highly specific chemical probes to identify epigenetic regulators of intestinal epithelial biology.</div> <div itemprodp="datePublished">Sat Feb 13 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33154396"> <div itemprop="name">Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Konger RL,Ren L,Sahu RP,Derr-Yellin E,Kim YL</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to challenge current models that suggest that persistence of cancer risk in the absence of continued carcinogen exposures is simply a function of stochastically arranged, long-lived but dormant epithelial clonal stem cells mutants.</div> <div itemprodp="datePublished">Thu Nov 05 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32019910"> <div itemprop="name">Oncogene-dependent function of BRG1 in hepatocarcinogenesis.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Wang P,Song X,Cao D,Cui K,Wang J,Utpatel K,Shang R,Wang H,Che L,Evert M,Zhao K,Calvisi DF,Chen X</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to propose BRG1 can be both oncogenic and tumor suppressive depending on the oncogenic stimuli during hepatocarcinogenesis.</div> <div itemprodp="datePublished">Tue Feb 04 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33063669"> <div itemprop="name">Secondary ossification center induces and protects growth plate structure.</div> </a> <div itemprop="about">eLife</div> <div itemprop="author">Xie M,Gol'din P,Herdina AN,Estefa J,Medvedeva EV,Li L,Newton PT,Kotova S,Shavkuta B,Saxena A,Shumate LT,Metscher BD,Großschmidt K,Nishimori S,Akovantseva A,Usanova AP,Kurenkova AD,Kumar A,Arregui IL,Tafforeau P,Fried K,Carlström M,Simon A,Gasser C,Kronenberg HM,Bastepe M,Cooper KL,Timashev P,Sanchez S,Adameyko I,Eriksson A,Chagin AS</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to understand the role of the secondary ossification center (SOC).</div> <div itemprodp="datePublished">Fri Oct 16 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32999402"> <div itemprop="name">High-fat diet and estrogen impacts the colon and its transcriptome in a sex-dependent manner.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Hases L,Archer A,Indukuri R,Birgersson M,Savva C,Korach-André M,Williams C</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate how HFD and estrogens modulate the colon microenvironment in a sex- and ER-specific manner.</div> <div itemprodp="datePublished">Wed Sep 30 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32049007"> <div itemprop="name">Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Di Magno L,Manni S,Di Pastena F,Coni S,Macone A,Cairoli S,Sambucci M,Infante P,Moretti M,Petroni M,Nicoletti C,Capalbo C,De Smaele E,Di Marcotullio L,Giannini G,Battistini L,Goffredo BM,Iorio E,Agostinelli E,Maroder M,Canettieri G</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show here that at clinically relevant concentrations, phenformin elicits a significant therapeutic effect through a redox-dependent but complex I-independent mechanism.</div> <div itemprodp="datePublished">Tue Feb 11 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32872195"> <div itemprop="name">Positive Effects of Preventive Nutrition Supplement on Anticancer Radiotherapy in Lung Cancer Bearing Mice.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Liu YM,Wu TH,Chiu YH,Wang H,Li TL,Hsia S,Chan YL,Wu CJ</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to demonstrate that the prescription of the TNuF total nutrition formula before and after cancer diagnosis attains similar benefits in testing subjects with typical anticancer RT.</div> <div itemprodp="datePublished">Fri Aug 28 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32301704"> <div itemprop="name">Yolk-sac-derived macrophages progressively expand in the mouse kidney with age.</div> </a> <div itemprop="about">eLife</div> <div itemprop="author">Ide S,Yahara Y,Kobayashi Y,Strausser SA,Ide K,Watwe A,Xu-Vanpala S,Privratsky JR,Crowley SD,Shinohara ML,Alman BA,Souma T</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunoflourescence to find that yolk-sac-derived macrophages progressively expand in number with age and become a major contributor to the renal macrophage population in older mice.</div> <div itemprodp="datePublished">Fri Apr 17 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32872532"> <div itemprop="name">Modulated Electro-Hyperthermia-Induced Tumor Damage Mechanisms Revealed in Cancer Models.</div> </a> <div itemprop="about">International journal of molecular sciences</div> <div itemprop="author">Krenacs T,Meggyeshazi N,Forika G,Kiss E,Hamar P,Szekely T,Vancsik T</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to review the mEHT-related damage mechanisms published in tumor models.</div> <div itemprodp="datePublished">Sat Aug 29 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/33317084"> <div itemprop="name">Bioinstructive Micro-Nanotextured Zirconia Ceramic Interfaces for Guiding and Stimulating an Osteogenic Response In Vitro.</div> </a> <div itemprop="about">Nanomaterials (Basel, Switzerland)</div> <div itemprop="author">Elena Sima L,Bonciu A,Baciu M,Anghel I,Dumitrescu LN,Rusen L,Dinca V</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry-immunoflourescence to show parallel micro line anisotropic surfaces are able to guide cell growth only for the steep surfaces, while the curved ones reduce the initial response and show the lowest osteogenic response.</div> <div itemprodp="datePublished">Wed Dec 09 00:00:00 EST 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/32451442"> <div itemprop="name">Visualizing the functional 3D shape and topography of long noncoding RNAs by single-particle atomic force microscopy and in-solution hydrodynamic techniques.</div> </a> <div itemprop="about">Nature protocols</div> <div itemprop="author">Uroda T,Chillón I,Annibale P,Teulon JM,Pessey O,Karuppasamy M,Pellequer JL,Marcia M</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry to present a protocol that integrates non-denaturing lncRNA purification with in-solution hydrodynamic analysis and single-particle atomic force microscopy (AFM) imaging to produce highly homogeneous lncRNA preparations and visualize their 3D topology at ~15-Å resolution.</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31447347"> <div itemprop="name">GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.</div> </a> <div itemprop="about">Cancer cell</div> <div itemprop="author">Mondragón L,Mhaidly R,De Donatis GM,Tosolini M,Dao P,Martin AR,Pons C,Chiche J,Jacquin M,Imbert V,Proïcs E,Boyer L,Doye A,Luciano F,Neels JG,Coutant F,Fabien N,Sormani L,Rubio-Patiño C,Bossowski JP,Muller F,Marchetti S,Villa E,Peyron JF,Gaulard P,Lemonnier F,Asnafi V,Genestier L,Benhida R,Fournié JJ,Passeron T,Ricci JE,Verhoeyen E</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to suggest the therapeutic potential of targeting NF-κB signaling in AITL and provide a model for future AITL therapeutic investigations.</div> <div itemprodp="datePublished">Mon Sep 16 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31474569"> <div itemprop="name">Single-Cell Transcriptomics in Medulloblastoma Reveals Tumor-Initiating Progenitors and Oncogenic Cascades during Tumorigenesis and Relapse.</div> </a> <div itemprop="about">Cancer cell</div> <div itemprop="author">Zhang L,He X,Liu X,Zhang F,Huang LF,Potter AS,Xu L,Zhou W,Zheng T,Luo Z,Berry KP,Pribnow A,Smith SM,Fuller C,Jones BV,Fouladi M,Drissi R,Yang ZJ,Gustafson WC,Remke M,Pomeroy SL,Girard EJ,Olson JM,Morrissy AS,Vladoiu MC,Zhang J,Tian W,Xin M,Taylor MD,Potter SS,Roussel MF,Weiss WA,Lu QR</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that glial lineage-associated OLIG2+ progenitors are tumor-initiating cells during medulloblastoma tumorigenesis and relapse.</div> <div itemprodp="datePublished">Mon Sep 16 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31513797"> <div itemprop="name">Suppressive and Gut-Reparative Functions of Human Type 1 T Regulatory Cells.</div> </a> <div itemprop="about">Gastroenterology</div> <div itemprop="author">Cook L,Stahl M,Han X,Nazli A,MacDonald KN,Wong MQ,Tsai K,Dizzell S,Jacobson K,Bressler B,Kaushic C,Vallance BA,Steiner TS,Levings MK</div> <div itemprop="description">MA5-14520 was used in Flow cytometry/Cell sorting to develop methods to isolate and expand human type 1 Treg cells and define their functions.</div> <div itemprodp="datePublished">Sun Dec 01 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30563891"> <div itemprop="name">Inhibitor of Differentiation-1 Sustains Mutant <i>KRAS</i>-Driven Progression, Maintenance, and Metastasis of Lung Adenocarcinoma via Regulation of a FOSL1 Network.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Román M,López I,Guruceaga E,Baraibar I,Ecay M,Collantes M,Nadal E,Vallejo A,Cadenas S,Miguel ME,Jang JH,Martin-Uriz PS,Castro-Labrador L,Vilas-Zornoza A,Lara-Astiaso D,Ponz-Sarvise M,Rolfo C,Santos ES,Raez LE,Taverna S,Behrens C,Weder W,Wistuba II,Vicent S,Gil-Bazo I</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to highlight the prognostic significance of the transcriptional regulator Id1 in KRAS-mutant lung adenocarcinoma and provide mechanistic insight into how it controls tumor growth and metastasis.</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30842215"> <div itemprop="name">Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells.</div> </a> <div itemprop="about">Genes & development</div> <div itemprop="author">Rajakulendran N,Rowland KJ,Selvadurai HJ,Ahmadi M,Park NI,Naumenko S,Dolma S,Ward RJ,So M,Lee L,MacLeod G,Pasiliao C,Brandon C,Clarke ID,Cusimano MD,Bernstein M,Batada N,Angers S,Dirks PB</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to report context-specific actions of Wnt/βcatenin signaling in directing cellular fate specification and renewal.</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30185824"> <div itemprop="name">RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.</div> </a> <div itemprop="about">Cell death and differentiation</div> <div itemprop="author">Anderton H,Bandala-Sanchez E,Simpson DS,Rickard JA,Ng AP,Di Rago L,Hall C,Vince JE,Silke J,Liccardi G,Feltham R</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to show that genetic deletion of Ripk1 licenses TRADD to complex with FADD-caspase-8 and activates caspase-8 during development.</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31291759"> <div itemprop="name">Hepatic Forkhead Box Protein A3 Regulates ApoA-I (Apolipoprotein A-I) Expression, Cholesterol Efflux, and Atherogenesis.</div> </a> <div itemprop="about">Arteriosclerosis, thrombosis, and vascular biology</div> <div itemprop="author">Li Y,Xu Y,Jadhav K,Zhu Y,Yin L,Zhang Y</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to showed that FOXA3 directly bound to the promoter of the Apoa1 gene to regulate its transcription.</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30898150"> <div itemprop="name">Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.</div> </a> <div itemprop="about">Breast cancer research : BCR</div> <div itemprop="author">Kennedy SP,Han JZR,Portman N,Nobis M,Hastings JF,Murphy KJ,Latham SL,Cadell AL,Miladinovic D,Marriott GR,O'Donnell YEI,Shearer RF,Williams JT,Munoz AG,Cox TR,Watkins DN,Saunders DN,Timpson P,Lim E,Kolch W,Croucher DR</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show the inactivation of ERBB3/PI3K by these therapeutic antibodies is insufficient to inhibit the growth of ERBB2-amplified breast cancer cells.</div> <div itemprodp="datePublished">Thu Mar 21 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31033049"> <div itemprop="name">Astrocyte-to-astrocyte contact and a positive feedback loop of growth factor signaling regulate astrocyte maturation.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Li J,Khankan RR,Caneda C,Godoy MI,Haney MS,Krawczyk MC,Bassik MC,Sloan SA,Zhang Y</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to identify molecular markers of astrocyte maturation and established an in vitro assay for studying the mechanisms of astrocyte maturation.</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30794805"> <div itemprop="name">TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Zhang J,Liu P,Tao J,Wang P,Zhang Y,Song X,Che L,Sumazin P,Ribback S,Kiss A,Schaff Z,Cigliano A,Dombrowski F,Cossu C,Pascale RM,Calvisi DF,Monga SP,Chen X</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to study TEA domain-mediated transcriptional activity in yes-associated protein driven hepatoblastoma development.</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30364994"> <div itemprop="name">Human 3D Gastrointestinal Microtissue Barrier Function As a Predictor of Drug-Induced Diarrhea.</div> </a> <div itemprop="about">Toxicological sciences : an official journal of the Society of Toxicology</div> <div itemprop="author">Peters MF,Landry T,Pin C,Maratea K,Dick C,Wagoner MP,Choy AL,Barthlow H,Snow D,Stevens Z,Armento A,Scott CW,Ayehunie S</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show drug-induced diarrhea can be predicted by analyzing human 3D gastrointestinal microtissue barrier.</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30682231"> <div itemprop="name">Developmental changes in interkinetic nuclear migration dynamics with respect to cell-cycle progression in the mouse cerebral cortex ventricular zone.</div> </a> <div itemprop="about">The Journal of comparative neurology</div> <div itemprop="author">Fousse J,Gautier E,Patti D,Dehay C</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to examine the relationship between interkinetic nuclear migration and cell-cycle progression of apical progenitors in the ventricular zone at different stages of mouse cerebral corticogenesis.</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30857197"> <div itemprop="name">Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model.</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Linder B,Weirauch U,Ewe A,Uhmann A,Seifert V,Mittelbronn M,Harter PN,Aigner A,Kögel D</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to present data showing that the therapeutic application of siRNAs, formulated in nanoscale lipopolyplexes (LPP) based on polyethylenimine (PEI) and the phospholipid 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC), represents a promising new approach to target Stat3 in glioma.</div> <div itemprodp="datePublished">Fri Mar 08 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30912139"> <div itemprop="name">Prolonged elevated levels of c-kit+ progenitor cells after a myocardial infarction by beta 2 adrenergic receptor priming.</div> </a> <div itemprop="about">Journal of cellular physiology</div> <div itemprop="author">Finan A,Demion M,Sicard P,Guisiano M,Bideaux P,Monceaux K,Thireau J,Richard S</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that ß2-AR stimulation may improve the cardiac repair process by supporting an endogenous progenitor cell response but is not sufficient to improve the cardiac function.</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31253778"> <div itemprop="name">Conserved transcriptomic profile between mouse and human colitis allows unsupervised patient stratification.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Czarnewski P,Parigi SM,Sorini C,Diaz OE,Das S,Gagliani N,Villablanca EJ</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that cross-species comparison enables stratification of patients undistinguishable by other molecular approaches.</div> <div itemprodp="datePublished">Fri Jun 28 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31621585"> <div itemprop="name">Targeting the vascular-specific phosphatase PTPRB protects against retinal ganglion cell loss in a pre-clinical model of glaucoma.</div> </a> <div itemprop="about">eLife</div> <div itemprop="author">Thomson BR,Carota IA,Souma T,Soman S,Vestweber D,Quaggin SE</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to describe a novel approach to enhance canal formation in human and mice by deleting a single allele of the gene encoding the phosphatase PTPRB during development.</div> <div itemprodp="datePublished">Thu Oct 17 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31159231"> <div itemprop="name">Improved Oxygen Supply to Multicellular Spheroids Using A Gas-permeable Plate and Embedded Hydrogel Beads.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Mihara H,Kugawa M,Sayo K,Tao F,Shinohara M,Nishikawa M,Sakai Y,Akama T,Kojima N</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to indicate that the combination of gas-permeable culture equipment and embedded hydrogel beads improves culture 3D spheroids produced from primary or PDX-expanded tumor cells.</div> <div itemprodp="datePublished">Fri May 31 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31056286"> <div itemprop="name">Intra-Tumoral Metabolic Zonation and Resultant Phenotypic Diversification Are Dictated by Blood Vessel Proximity.</div> </a> <div itemprop="about">Cell metabolism</div> <div itemprop="author">Kumar S,Sharife H,Kreisel T,Mogilevsky M,Bar-Lev L,Grunewald M,Aizenshtein E,Karni R,Paldor I,Shlomi T,Keshet E</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to reveal a previously unappreciated graded metabolic zonation directly impacting the acquisition of multiple aggressive tumor traits.</div> <div itemprodp="datePublished">Tue Jul 02 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30615449"> <div itemprop="name">Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer.</div> </a> <div itemprop="about">Journal of medicinal chemistry</div> <div itemprop="author">de Moura Sperotto ND,Deves Roth C,Rodrigues-Junior VS,Ev Neves C,Reisdorfer Paula F,da Silva Dadda A,Bergo P,Freitas de Freitas T,Souza Macchi F,Moura S,Duarte de Souza AP,Campos MM,Valim Bizarro C,Santos DS,Basso LA,Machado P</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to evaluate novel pyrimidine-2,4-diones as inhibitors of human thymidine phosphorylase (hTP) activity.</div> <div itemprodp="datePublished">Thu Feb 14 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31341163"> <div itemprop="name">ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Bufalieri F,Infante P,Bernardi F,Caimano M,Romania P,Moretti M,Lospinoso Severini L,Talbot J,Melaiu O,Tanori M,Di Magno L,Bellavia D,Capalbo C,Puget S,De Smaele E,Canettieri G,Guardavaccaro D,Busino L,Peschiaroli A,Pazzaglia S,Giannini G,Melino G,Locatelli F,Gulino A,Ayrault O,Fruci D,Di Marcotullio L</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate the role of ERAP1 in the Hh signalling pathway and to show its effect in cancer and possible uses for therapeutic treatment.</div> <div itemprodp="datePublished">Wed Jul 24 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31149033"> <div itemprop="name">Preclinical efficacy of hK2 targeted [<sup>177</sup>Lu]hu11B6 for prostate cancer theranostics.</div> </a> <div itemprop="about">Theranostics</div> <div itemprop="author">Timmermand OV,Elgqvist J,Beattie KA,Örbom A,Larsson E,Eriksson SE,Thorek DLJ,Beattie BJ,Tran TA,Ulmert D,Strand SE</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to assessed the efficacy of hu11B6 labeled with a low LET beta-emitter, Lutetium-177 (177Lu) and investigated whether similar tumor killing and AR-enhancement is produced.</div> <div itemprodp="datePublished">Thu Jun 25 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31488827"> <div itemprop="name">CDK5-dependent phosphorylation and nuclear translocation of TRIM59 promotes macroH2A1 ubiquitination and tumorigenicity.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Sang Y,Li Y,Zhang Y,Alvarez AA,Yu B,Zhang W,Hu B,Cheng SY,Feng H</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to suggest targeting CDK5/TRIM59 signaling axis as a putative strategy for treating glioblastoma.</div> <div itemprodp="datePublished">Thu Sep 05 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31515519"> <div itemprop="name">The EYA3 tyrosine phosphatase activity promotes pulmonary vascular remodeling in pulmonary arterial hypertension.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Wang Y,Pandey RN,York AJ,Mallela J,Nichols WC,Hu YC,Molkentin JD,Wikenheiser-Brokamp KA,Hegde RS</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to establish EYA3 as a disease-modifying target whose function in the pathophysiology of pulmonary arterial hypertension can be targeted by available inhibitors.</div> <div itemprodp="datePublished">Thu Sep 12 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30706567"> <div itemprop="name">Liver-specific Sirtuin6 ablation impairs liver regeneration after 2/3 partial hepatectomy.</div> </a> <div itemprop="about">Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society</div> <div itemprop="author">Liu Q,Pu S,Chen L,Shen J,Cheng S,Kuang J,Li H,Wu T,Li R,Jiang W,Zou M,Zhang Z,Li Y,Li J,He J</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to suggest that Sirt6 LKO impaired liver regeneration via delayed cell cycle and impaired m-TOR and Akt activity.</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31413349"> <div itemprop="name">The undeveloped properties of GABA neurons in the ventral tegmental area promote energy intake for growth in juvenile rats.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Maejima Y,Yokota S,Horita S,Shimomura K</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to suggest that undeveloped properties of VTA GABA neurons in juvenile rats can promote higher EI regardless of high or less palatable feeding, and contribute to growth promotion.</div> <div itemprodp="datePublished">Wed Aug 14 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30944252"> <div itemprop="name">Disease-modifying bioactivity of intravenous cardiosphere-derived cells and exosomes in mdx mice.</div> </a> <div itemprop="about">JCI insight</div> <div itemprop="author">Rogers RG,Fournier M,Sanchez L,Ibrahim AG,Aminzadeh MA,Lewis MI,Marbán E</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate regenerative responses of cardiac and skeletal muscle tissue to intravenous cardiosphere-derived cells and exosomes in mdx mice.</div> <div itemprodp="datePublished">Thu Apr 04 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31861383"> <div itemprop="name">Disruption of Cancer Metabolic SREBP1/miR-142-5p Suppresses Epithelial-Mesenchymal Transition and Stemness in Esophageal Carcinoma.</div> </a> <div itemprop="about">Cells</div> <div itemprop="author">Huang CM,Huang CS,Hsu TN,Huang MS,Fong IH,Lee WH,Liu SC</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to investigate the therapeutic potential of SREBP1 and associated signaling in esophageal cancer.</div> <div itemprodp="datePublished">Wed Dec 18 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31873117"> <div itemprop="name">SMO-M2 mutation does not support cell-autonomous Hedgehog activity in cerebellar granule cell precursors.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Petroni M,Sahùn Roncero M,Ramponi V,Fabretti F,Nicolis Di Robilant V,Moretti M,Alfano V,Corsi A,De Panfilis S,Giubettini M,Di Giulio S,Capalbo C,Belardinilli F,Coppa A,Sardina F,Colicchia V,Pedretti F,Infante P,Cardinali B,Tessitore A,Canettieri G,De Smaele E,Giannini G</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to validate a new culture method to grow postnatal granule cell progenitors as hedgehog-dependent neurospheres with prolonged self-renewal and ability to differentiate into granule cells, under appropriate conditions.</div> <div itemprodp="datePublished">Mon Dec 23 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/31791407"> <div itemprop="name">Combination of laser and human adipose-derived stem cells in repair of rabbit anal sphincter injury: a new therapeutic approach.</div> </a> <div itemprop="about">Stem cell research & therapy</div> <div itemprop="author">Sarveazad A,Babahajian A,Yari A,Rayner CK,Mokhtare M,Babaei-Ghazani A,Agah S,Mahjoubi B,Shamseddin J,Yousefifard M</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to indicate that co-application of laser and hADSC therapy immediately after anal sphincter damage could improve subsequent sphincter function.</div> <div itemprodp="datePublished">Mon Dec 02 00:00:00 EST 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29763624"> <div itemprop="name">The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma.</div> </a> <div itemprop="about">Cancer cell</div> <div itemprop="author">Momcilovic M,Bailey ST,Lee JT,Fishbein MC,Braas D,Go J,Graeber TG,Parlati F,Demo S,Li R,Walser TC,Gricowski M,Shuman R,Ibarra J,Fridman D,Phelps ME,Badran K,St John M,Bernthal NM,Federman N,Yanagawa J,Dubinett SM,Sadeghi S,Christofk HR,Shackelford DB</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to perform in vivo metabolic profiling and molecular analysis of lung squamous cell carcinoma (SCC) to identify metabolic nodes to therapeutically target.</div> <div itemprodp="datePublished">Mon May 14 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29572225"> <div itemprop="name">Therapeutic Targeting of Sunitinib-Induced AR Phosphorylation in Renal Cell Carcinoma.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Adelaiye-Ogala R,Damayanti NP,Orillion AR,Arisa S,Chintala S,Titus MA,Kao C,Pili R</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to show the potential role of androgen receptor as a target for therapeutic interventions, in combination with receptor tyrosine kinase inhibitor, to overcome drug resistance in renal cell carcinoma.</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30127719"> <div itemprop="name">Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.</div> </a> <div itemprop="about">Frontiers in molecular neuroscience</div> <div itemprop="author">Xiao D,Jin K,Xiang M</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to study the role of Ldb1 in retinal development.</div> <div itemprodp="datePublished">Wed Sep 30 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29030460"> <div itemprop="name">HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Efimova EV,Ricco N,Labay E,Mauceri HJ,Flor AC,Ramamurthy A,Sutton HG,Weichselbaum RR,Kron SJ</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to report that pitavastatin and other lipophilic statins are potent inhibitors of DSB repair in breast and melanoma models both in vitro and in vivo.</div> <div itemprodp="datePublished">Thu Feb 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29339161"> <div itemprop="name">A new genetically engineered mouse model of choroid plexus carcinoma.</div> </a> <div itemprop="about">Biochemical and biophysical research communications</div> <div itemprop="author">El Nagar S,Zindy F,Moens C,Martin L,Plassard D,Roussel MF,Lamonerie T,Billon N</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to generate a novel mouse model of choroid plexus carcinoma (CPC) to elucidate the mechanism of CPC formation and develop successful therapies.</div> <div itemprodp="datePublished">Mon Feb 05 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29435048"> <div itemprop="name">Luteinizing hormone compromises the <i>in vivo</i> anti-tumor effect of cisplatin on human epithelial ovarian cancer cells.</div> </a> <div itemprop="about">Oncology letters</div> <div itemprop="author">Huang Y,Zhou Y,Xia L,Tang J,Wen H,Zhang M</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to study the effect of cisplatin and/or lutenizing hormone on platinum resistance in ovarian cancer.</div> <div itemprodp="datePublished">Thu Mar 01 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30532756"> <div itemprop="name">Divergent Innate and Epithelial Functions of the RNA-Binding Protein HuR in Intestinal Inflammation.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Christodoulou-Vafeiadou E,Ioakeimidis F,Andreadou M,Giagkas G,Stamatakis G,Reczko M,Samiotaki M,Papanastasiou AD,Karakasiliotis I,Kontoyiannis DL</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that epithelial and myeloid HuR affect different cellular dynamics in the intestine that need to be carefully considered for its pharmacological exploitation and points toward potential windows for harnessing HuR functions in intestinal inflammation.</div> <div itemprodp="datePublished">Wed Oct 02 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30697580"> <div itemprop="name">Development of a murine intravesical orthotopic human bladder cancer (mio-hBC) model.</div> </a> <div itemprop="about">American journal of clinical and experimental urology</div> <div itemprop="author">Raven PA,D'Costa NM,Moskalev I,Tan Z,Frees S,Chavez-Munoz C,So AI</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry on paraffin embedded tissues to develop a murine intravesical orthotopic human bladder cancer (mio-hBC) model for the establishment of superficial urothelial cell carcinomas.</div> <div itemprodp="datePublished">Thu Oct 01 00:00:00 EDT 2020</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29649254"> <div itemprop="name">UXT is required for spermatogenesis in mice.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Schafler ED,Thomas PA,Ha S,Wang Y,Bermudez-Hernandez K,Tang Z,Fenyö D,Vigodner M,Logan SK</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to reveal ubiquitous expressed transcript is required for spermatogenesis as it regulates distinct transcriptional programs in spermatogonial stem cells and differentiating spermatogonia.</div> <div itemprodp="datePublished">Fri Jul 27 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29379130"> <div itemprop="name">DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Tögel L,Nightingale R,Wu R,Chüeh AC,Al-Obaidi S,Luk I,Dávalos-Salas M,Chionh F,Murone C,Buchanan DD,Chatterton Z,Sieber OM,Arango D,Tebbutt NC,Williams D,Dhillon AS,Mariadason JM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show that DUSP5 plays a limited role in regulating ERK signalling associated with the growth of colorectal tumours.</div> <div itemprodp="datePublished">Mon Jan 29 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29886545"> <div itemprop="name">Effects of Amyloid-β Peptide on the Biology of Human Neural Stem Cells.</div> </a> <div itemprop="about">Methods in molecular biology (Clifton, N.J.)</div> <div itemprop="author">Bernabeu-Zornoza A,Coronel R,Lachgar M,Palmer C,Liste I</div> <div itemprop="description">MA5-14520 was used in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot to describe the preparation of different forms (monomeric, oligomeric and fibrillary) of Aβ peptide and subsequent cell treatment, followed by the analysis of the effects on toxicity, cell proliferation and cell fate specification of hNS1 cells.</div> <div itemprodp="datePublished">Mon Jul 22 00:00:00 EDT 2019</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29298894"> <div itemprop="name">Tumor-extrinsic discoidin domain receptor 1 promotes mammary tumor growth by regulating adipose stromal interleukin 6 production in mice.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Sun X,Gupta K,Wu B,Zhang D,Yuan B,Zhang X,Chiang HC,Zhang C,Curiel TJ,Bendeck MP,Hursting S,Hu Y,Li R</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate the importance of host Discoidin domain receptor 1 (DDR1) in the promotion of mammary tumour growth in mice, and reveal its regulatory role in the expression of IL-6 by adipose cells.</div> <div itemprodp="datePublished">Fri Feb 23 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/30566861"> <div itemprop="name">Autoreactive, Low-Affinity T Cells Preferentially Drive Differentiation of Short-Lived Memory B Cells at the Expense of Germinal Center Maintenance.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Jain RW,Parham KA,Tesfagiorgis Y,Craig HC,Romanchik E,Kerfoot SM</div> <div itemprop="description">MA5-14520 was used in Flow cytometry/Cell sorting to characterise germinal centre kinetics and B cell fate choices in a response to the autoantigen myelin oligodendrocyte glycoprotein (MOG).</div> <div itemprodp="datePublished">Tue Dec 18 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29416709"> <div itemprop="name">Low-dose statin treatment increases prostate cancer aggressiveness.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Caro-Maldonado A,Camacho L,Zabala-Letona A,Torrano V,Fernández-Ruiz S,Zamacola-Bascaran K,Arreal L,Valcárcel-Jiménez L,Martín-Martín N,Flores JM,Cortazar AR,Zúñiga-García P,Arruabarrena-Aristorena A,Guillaumond F,Cabrera D,Falcón-Perez JM,Aransay AM,Gomez-Muñoz A,Olivan M,Morote J,Carracedo A</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry on paraffin embedded tissues to reveal a prostate cancer experimental system where statins exhibit an undesirable effect, and warrant further research to address the relevance and implications of this observation in human prostate cancer.</div> <div itemprodp="datePublished">Fri Jan 05 00:00:00 EST 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29724996"> <div itemprop="name">WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Abu-Remaileh M,Khalaileh A,Pikarsky E,Aqeilan RI</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to to study the effect of specific targeted deletion of Wwox on liver biology and hepatocellular carcinoma.</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2018</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29088697"> <div itemprop="name">Kctd13 deletion reduces synaptic transmission via increased RhoA.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Escamilla CO,Filonova I,Walker AK,Xuan ZX,Holehonnur R,Espinosa F,Liu S,Thyme SB,López-García IA,Mendoza DB,Usui N,Ellegood J,Eisch AJ,Konopka G,Lerch JP,Schier AF,Speed HE,Powell CM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to determine the function of KCTD13 in the mammalian brain.</div> <div itemprodp="datePublished">Thu Nov 09 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28977496"> <div itemprop="name">Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.</div> </a> <div itemprop="about">Nucleic acids research</div> <div itemprop="author">Schuhwerk H,Bruhn C,Siniuk K,Min W,Erener S,Grigaravicius P,Krüger A,Ferrari E,Zubel T,Lazaro D,Monajembashi S,Kiesow K,Kroll T,Bürkle A,Mangerich A,Hottiger M,Wang ZQ</div> <div itemprop="description">MA5-14520 was used in Immunocytochemistry to investigate the mechanism of the PARP1 responses to genotoxic stress.</div> <div itemprodp="datePublished">Thu Nov 02 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28062503"> <div itemprop="name">Protective Aptitude of Annexin A1 in Arterial Neointima Formation in Atherosclerosis-Prone Mice-Brief Report.</div> </a> <div itemprop="about">Arteriosclerosis, thrombosis, and vascular biology</div> <div itemprop="author">de Jong RJ,Paulin N,Lemnitzer P,Viola JR,Winter C,Ferraro B,Grommes J,Weber C,Reutelingsperger C,Drechsler M,Soehnlein O</div> <div itemprop="description">MA514520 was used in immunohistochemistry - paraffin section to examine the role of the proresolving protein annexin A1 in healing after wire injury</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28653846"> <div itemprop="name">In Vivo and Mechanistic Studies on Antitumor Lead 7-Methoxy-4-(2-methylquinazolin-4-yl)-3,4-dihydroquinoxalin-2(1H)-one and Its Modification as a Novel Class of Tubulin-Binding Tumor-Vascular Disrupting Agents.</div> </a> <div itemprop="about">Journal of medicinal chemistry</div> <div itemprop="author">Cui MT,Jiang L,Goto M,Hsu PL,Li L,Zhang Q,Wei L,Yuan SJ,Hamel E,Morris-Natschke SL,Lee KH,Xie L</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to reveal a class of tubulin-binding tumor-vascular disrupting agents that target established blood vessels in tumors.</div> <div itemprodp="datePublished">Thu Jul 13 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28647349"> <div itemprop="name">Inhibitor of Apoptosis Proteins (IAPs) Limit RIPK1-Mediated Skin Inflammation.</div> </a> <div itemprop="about">The Journal of investigative dermatology</div> <div itemprop="author">Anderton H,Rickard JA,Varigos GA,Lalaoui N,Silke J</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry-immunofluorescence to determine the role of inhibitor of apoptosis proteins (IAPs) in skin homeostasis.</div> <div itemprodp="datePublished">Wed Nov 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28118080"> <div itemprop="name">Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma.</div> </a> <div itemprop="about">Cell cycle (Georgetown, Tex.)</div> <div itemprop="author">Che L,Pilo MG,Cigliano A,Latte G,Simile MM,Ribback S,Dombrowski F,Evert M,Chen X,Calvisi DF</div> <div itemprop="description">MA514520 was used in immunohistochemistry - paraffin section to test if de novo lipogenesis is required for liver carcinogenesis</div> <div itemprodp="datePublished">Sun Mar 19 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28486600"> <div itemprop="name">Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling.</div> </a> <div itemprop="about">Human molecular genetics</div> <div itemprop="author">Li J,Lu D,Liu H,Williams BO,Overbeek PA,Lee B,Zheng L,Yang T</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry on paraffin embedded tissues to establish that STAT3 inhibition may be a potential treatment of SCLT1-associated cystic kidney.</div> <div itemprodp="datePublished">Tue Aug 01 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28069738"> <div itemprop="name">FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.</div> </a> <div itemprop="about">Molecular and cellular biology</div> <div itemprop="author">Yamauchi T,Nishiyama M,Moroishi T,Kawamura A,Nakayama KI</div> <div itemprop="description">MA514520 was used in immunohistochemistry - paraffin section to confirm that FBXL5 contributes to regulation of neural stem-progenitor cells proliferation during mammalian brain development</div> <div itemprodp="datePublished">Sat Apr 15 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28265230"> <div itemprop="name">Electrotransfer of plasmid DNA radiosensitizes B16F10 tumors through activation of immune response.</div> </a> <div itemprop="about">Radiology and oncology</div> <div itemprop="author">Savarin M,Kamensek U,Cemazar M,Heller R,Sersa G</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry on paraffin embedded tissues to determine the effect of gene transfer of plasmid encoding shRNA for silencing endoglin on radiosensitisation of melanoma B16F10 tumours.</div> <div itemprodp="datePublished">Wed Mar 01 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28249000"> <div itemprop="name">Stabilization of HIF-1α and HIF-2α, up-regulation of MYCC and accumulation of stabilized p53 constitute hallmarks of CNS-PNET animal model.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Malchenko S,Sredni ST,Bi Y,Margaryan NV,Boyineni J,Mohanam I,Tomita T,Davuluri RV,Soares MB</div> <div itemprop="description">MA514520 was used in immunohistochemistry - paraffin section to assess mechanisms of tumorigenesis in the mouse model of CNS primitive neuroectodermal tumors</div> <div itemprodp="datePublished">Thu Aug 17 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28276480"> <div itemprop="name">Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Coni S,Mancuso AB,Di Magno L,Sdruscia G,Manni S,Serrao SM,Rotili D,Spiombi E,Bufalieri F,Petroni M,Kusio-Kobialka M,De Smaele E,Ferretti E,Capalbo C,Mai A,Niewiadomski P,Screpanti I,Di Marcotullio L,Canettieri G</div> <div itemprop="description">MA514520 was used in immunohistochemistry - paraffin section to analyze the contributions of developmental Hedgehog signaling effectors HDAC1 and HDAC2 in SHH Medulloblastoma</div> <div itemprodp="datePublished">Thu Mar 09 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28232723"> <div itemprop="name">Mutant Kras- and p16-regulated NOX4 activation overcomes metabolic checkpoints in development of pancreatic ductal adenocarcinoma.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Ju HQ,Ying H,Tian T,Ling J,Fu J,Lu Y,Wu M,Yang L,Achreja A,Chen G,Zhuang Z,Wang H,Nagrath D,Yao J,Hung MC,DePinho RA,Huang P,Xu RH,Chiao PJ</div> <div itemprop="description">MA514520 was used in immunohistochemistry - paraffin section to determine the contribution of NOX4 to the development of pancreatic ductal adenocarcinoma</div> <div itemprodp="datePublished">Fri Feb 24 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28220783"> <div itemprop="name">An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Vallejo A,Perurena N,Guruceaga E,Mazur PK,Martinez-Canarias S,Zandueta C,Valencia K,Arricibita A,Gwinn D,Sayles LC,Chuang CH,Guembe L,Bailey P,Chang DK,Biankin A,Ponz-Sarvise M,Andersen JB,Khatri P,Bozec A,Sweet-Cordero EA,Sage J,Lecanda F,Vicent S</div> <div itemprop="description">MA514520 was used in immunohistochemistry to report FOSL1 as a common transcriptional signature across mutant KRAS cancers of distinct tissue origin</div> <div itemprodp="datePublished">Tue Feb 21 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27966456"> <div itemprop="name">Ablating all three retinoblastoma family members in mouse lung leads to neuroendocrine tumor formation.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Lázaro S,Pérez-Crespo M,Enguita AB,Hernández P,Martínez-Palacio J,Oteo M,Sage J,Paramio JM,Santos M</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry (Paraffin) to to investigate the role of two Rb family proteins in lung tumorigenesis.</div> <div itemprodp="datePublished">Tue Jan 17 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28272472"> <div itemprop="name">Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Sgourdou P,Mishra-Gorur K,Saotome I,Henagariu O,Tuysuz B,Campos C,Ishigame K,Giannikou K,Quon JL,Sestan N,Caglayan AO,Gunel M,Louvi A</div> <div itemprop="description">MA514520 was used in immunohistochemistry to reveal critical and diverse functions of WD repeat domain 62 in neocortical development</div> <div itemprodp="datePublished">Wed Mar 08 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28076334"> <div itemprop="name">Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtype.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Hopkinson BM,Klitgaard MC,Petersen OW,Villadsen R,Rønnov-Jessen L,Kim J</div> <div itemprop="description">MA514520 was used in immunocytochemistry to discuss estrogen receptor regulation and function in normal breast and breast cancer</div> <div itemprodp="datePublished">Tue Feb 07 00:00:00 EST 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28649985"> <div itemprop="name">Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Zhang X,Chiang HC,Wang Y,Zhang C,Smith S,Zhao X,Nair SJ,Michalek J,Jatoi I,Lautner M,Oliver B,Wang H,Petit A,Soler T,Brunet J,Mateo F,Angel Pujana M,Poggi E,Chaldekas K,Isaacs C,Peshkin BN,Ochoa O,Chedin F,Theoharis C,Sun LZ,Curiel TJ,Elledge R,Jin VX,Hu Y,Li R</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to show pausing of RNA polymerase II contributes to BRCA1-associated R-loop accumulation and breast cancer development.</div> <div itemprodp="datePublished">Mon Jun 26 00:00:00 EDT 2017</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/29209567"> <div itemprop="name">Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure inhibit prostate tumor growth in TRAMP mice.</div> </a> <div itemprop="about">Oncoimmunology</div> <div itemprop="author">Mikyskova R,Indrova M,Stepanek I,Kanchev I,Bieblova J,Vosahlikova S,Moserova I,Truxova I,Fucikova J,Bartunkova J,Spisek R,Sedlacek R,Reinis M</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that dendritic cell based vaccines represent a tool for the treatment of human prostate cancer.</div> <div itemprodp="datePublished">Tue Jan 12 00:00:00 EST 2021</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/28084216"> <div itemprop="name">DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Herrtwich L,Nanda I,Evangelou K,Nikolova T,Horn V,Erny D,Stefanowski J,Rogell L,Klein C,Gharun K,Follo M,Seidl M,Kremer B,Münke N,Senges J,Fliegauf M,Aschman T,Pfeifer D,Sarrazin S,Sieweke MH,Wagner D,Dierks C,Haaf T,Ness T,Zaiss MM,Voll RE,Deshmukh SD,Prinz M,Goldmann T,Hölscher C,Hauser AE,Lopez-Contreras AJ,Grün D,Gorgoulis V,Diefenbach A,Henneke P,Triantafyllopoulou A</div> <div itemprop="description">MA514520 was used in immunohistochemistry - frozen section to describe how TLR2 signaling promotes macrophage polyploidy</div> <div itemprodp="datePublished">Thu Nov 17 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26769348"> <div itemprop="name">IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment.</div> </a> <div itemprop="about">EMBO molecular medicine</div> <div itemprop="author">Catarinella M,Monestiroli A,Escobar G,Fiocchi A,Tran NL,Aiolfi R,Marra P,Esposito A,Cipriani F,Aldrighetti L,Iannacone M,Naldini L,Guidotti LG,Sitia G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study cessation of colorectal cancer colonization of the liver by acting on the hepatic microenvironment by IFN-alpha gene/cell therapy</div> <div itemprodp="datePublished">Mon Feb 01 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27197175"> <div itemprop="name">Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Albino D,Civenni G,Dallavalle C,Roos M,Jahns H,Curti L,Rossi S,Pinton S,D'Ambrosio G,Sessa F,Hall J,Catapano CV,Carbone GM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report that control by ESE3/EHF over the Lin28/let-7 axis is a critical barrier to malignant transformation in cancer stem-like cells</div> <div itemprodp="datePublished">Wed Jun 15 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26773147"> <div itemprop="name">Vaccine Induction of Lymph Node-Resident Simian Immunodeficiency Virus Env-Specific T Follicular Helper Cells in Rhesus Macaques.</div> </a> <div itemprop="about">Journal of immunology (Baltimore, Md. : 1950)</div> <div itemprop="author">Vargas-Inchaustegui DA,Demers A,Shaw JM,Kang G,Ball D,Tuero I,Musich T,Mohanram V,Demberg T,Karpova TS,Li Q,Robert-Guroff M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study lymph node-resident simian immunodeficiency virus env-specific T follicular helper cells due to vaccine induction in Rhesus Macaques</div> <div itemprodp="datePublished">Mon Feb 15 00:00:00 EST 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26830354"> <div itemprop="name">Generation of Homogenous Three-Dimensional Pancreatic Cancer Cell Spheroids Using an Improved Hanging Drop Technique.</div> </a> <div itemprop="about">Tissue engineering. Part C, Methods</div> <div itemprop="author">Ware MJ,Colbert K,Keshishian V,Ho J,Corr SJ,Curley SA,Godin B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study the generation of homogenous three-dimensional pancreatic cancer cell spheroids and their improved hanging drop technique</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27446423"> <div itemprop="name">Attempt towards a novel classification of triple-negative breast cancer using immunohistochemical markers.</div> </a> <div itemprop="about">Oncology letters</div> <div itemprop="author">Liu YX,Wang KR,Xing H,Zhai XJ,Wang LP,Wang W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to classify triple-negative breast cancer into subtypes</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27350069"> <div itemprop="name">High Fat Diets Induce Colonic Epithelial Cell Stress and Inflammation that is Reversed by IL-22.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Gulhane M,Murray L,Lourie R,Tong H,Sheng YH,Wang R,Kang A,Schreiber V,Wong KY,Magor G,Denman S,Begun J,Florin TH,Perkins A,Cuív PÓ,McGuckin MA,Hasnain SZ</div> <div itemprop="description">MA5-14520 was used in western blot to assess the induction of colonic epithelial cell stress and inflammation reversed by IL-22 due to high fat diets</div> <div itemprodp="datePublished">Tue Jun 28 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27687499"> <div itemprop="name">Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Dubail J,Vasudevan D,Wang LW,Earp SE,Jenkins MW,Haltiwanger RS,Apte SS</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section describe a role for ADAMTS9 in ocular morphogenesis</div> <div itemprodp="datePublished">Fri Sep 30 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26934552"> <div itemprop="name">Immunogenomics reveal molecular circuits of diclofenac induced liver injury in mice.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Lee EH,Oh JH,Selvaraj S,Park SM,Choi MS,Spanel R,Yoon S,Borlak J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to determine the induction of liver injury in mice due to molecular circuits of diclofenac revealed by immunogenomics</div> <div itemprodp="datePublished">Tue Mar 22 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27007157"> <div itemprop="name">Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Mehta FF,Son J,Hewitt SC,Jang E,Lydon JP,Korach KS,Chung SH</div> <div itemprop="description">MA5-14520 was used in Western Blotting to describe the regulation and function in the cervix of of progesterone receptor in the mouse vagina and uterus.</div> <div itemprodp="datePublished">Tue Apr 05 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/27007157"> <div itemprop="name">Distinct functions and regulation of epithelial progesterone receptor in the mouse cervix, vagina, and uterus.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Mehta FF,Son J,Hewitt SC,Jang E,Lydon JP,Korach KS,Chung SH</div> <div itemprop="description">MA5-14520 was used in Western Blotting to describe the regulation and function in the cervix of of progesterone receptor in the mouse vagina and uterus.</div> <div itemprodp="datePublished">Tue Apr 05 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25751815"> <div itemprop="name">A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.</div> </a> <div itemprop="about">Nature medicine</div> <div itemprop="author">Wang P,Alvarez-Perez JC,Felsenfeld DP,Liu H,Sivendran S,Bender A,Kumar A,Sanchez R,Scott DK,Garcia-Ocaña A,Stewart AF</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry and immunohistochemistry to identify analogs of harmine as a new class of human beta cell mitogenic compounds and identify the pathways they activate.</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25751815"> <div itemprop="name">A high-throughput chemical screen reveals that harmine-mediated inhibition of DYRK1A increases human pancreatic beta cell replication.</div> </a> <div itemprop="about">Nature medicine</div> <div itemprop="author">Wang P,Alvarez-Perez JC,Felsenfeld DP,Liu H,Sivendran S,Bender A,Kumar A,Sanchez R,Scott DK,Garcia-Ocaña A,Stewart AF</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry and immunohistochemistry to identify analogs of harmine as a new class of human beta cell mitogenic compounds and identify the pathways they activate.</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26479922"> <div itemprop="name">Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma.</div> </a> <div itemprop="about">Nature medicine</div> <div itemprop="author">Adachi T,Kobayashi T,Sugihara E,Yamada T,Ikuta K,Pittaluga S,Saya H,Amagai M,Nagao K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to research skin-resident memory T cell homeostasis and lymphoma mediated by hair follicle-derived IL-7 and IL-15</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25383540"> <div itemprop="name">p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Zuo W,Zhang T,Wu DZ,Guan SP,Liew AA,Yamamoto Y,Wang X,Lim SJ,Vincent M,Lessard M,Crum CP,Xian W,McKeon F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate how DASC(p63/Krt5) regulates regeneration of tissue after influenza-induced lung damage.</div> <div itemprodp="datePublished">Thu Jan 29 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26502405"> <div itemprop="name">Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Finkin S,Yuan D,Stein I,Taniguchi K,Weber A,Unger K,Browning JL,Goossens N,Nakagawa S,Gunasekaran G,Schwartz ME,Kobayashi M,Kumada H,Berger M,Pappo O,Rajewsky K,Hoshida Y,Karin M,Heikenwalder M,Ben-Neriah Y,Pikarsky E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study hepatocellular carcinoma and ectopic lymphoid structures function as microniches for tumor progenitor cells</div> <div itemprodp="datePublished">Tue Dec 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25689256"> <div itemprop="name">Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Licht T,Dor-Wollman T,Ben-Zvi A,Rothe G,Keshet E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to evaluate an animal model for periventricular leukomalacia</div> <div itemprodp="datePublished">Mon Mar 02 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26348897"> <div itemprop="name">Hepatocellular carcinoma originates from hepatocytes and not from the progenitor/biliary compartment.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Mu X,Español-Suñer R,Mederacke I,Affò S,Manco R,Sempoux C,Lemaigre FP,Adili A,Yuan D,Weber A,Unger K,Heikenwälder M,Leclercq IA,Schwabe RF</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to elucidate the origin of hepatocellular carcinoma.</div> <div itemprodp="datePublished">Thu Oct 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26384380"> <div itemprop="name">Induction of the ChREBPβ Isoform Is Essential for Glucose-Stimulated β-Cell Proliferation.</div> </a> <div itemprop="about">Diabetes</div> <div itemprop="author">Zhang P,Kumar A,Katz LS,Li L,Paulynice M,Herman MA,Scott DK</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the relationship between ChREBPbeta and glucose in beta cells</div> <div itemprodp="datePublished">Tue Dec 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26441975"> <div itemprop="name">Meningeal Infiltration of the Spinal Cord by Non-Classically Activated B Cells is Associated with Chronic Disease Course in a Spontaneous B Cell-Dependent Model of CNS Autoimmune Disease.</div> </a> <div itemprop="about">Frontiers in immunology</div> <div itemprop="author">Dang AK,Tesfagiorgis Y,Jain RW,Craig HC,Kerfoot SM</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry on paraffin embedded tissues to characterise B cell infiltration of the spinal cord in a B cell-dependent spontaneous model of CNS autoimmunity, showing meningeal infiltration of the spinal cord by non-classically activated B cells.</div> <div itemprodp="datePublished">Wed Oct 07 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25624394"> <div itemprop="name">Unipotent, Atoh1+ progenitors maintain the Merkel cell population in embryonic and adult mice.</div> </a> <div itemprop="about">The Journal of cell biology</div> <div itemprop="author">Wright MC,Reed-Geaghan EG,Bolock AM,Fujiyama T,Hoshino M,Maricich SM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to characterize the Merkel cell population in embryonic and adult mice as unipotent, Atoh1+ progenitors</div> <div itemprodp="datePublished">Mon Feb 02 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26327622"> <div itemprop="name">KSHV Latency Locus Cooperates with Myc to Drive Lymphoma in Mice.</div> </a> <div itemprop="about">PLoS pathogens</div> <div itemprop="author">Sin SH,Kim Y,Eason A,Dittmer DP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study lymphoma in mice driven by Myc cooperating with the KSHV latency locus</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25747816"> <div itemprop="name">Disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2, a gene in the Down syndrome critical region.</div> </a> <div itemprop="about">Neurobiology of disease</div> <div itemprop="author">Liu W,Zhou H,Liu L,Zhao C,Deng Y,Chen L,Wu L,Mandrycky N,McNabb CT,Peng Y,Fuchs PN,Lu J,Sheen V,Qiu M,Mao M,Lu QR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to study a gene called Olig2, found in the Down syndrome critical region, shows disruption of neurogenesis and cortical development in transgenic mice misexpressing Olig2</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25142799"> <div itemprop="name">Does the WHO 2010 classification of pancreatic neuroendocrine neoplasms accurately characterize pancreatic neuroendocrine carcinomas?</div> </a> <div itemprop="about">Journal of gastroenterology</div> <div itemprop="author">Hijioka S,Hosoda W,Mizuno N,Hara K,Imaoka H,Bhatia V,Mekky MA,Tajika M,Tanaka T,Ishihara M,Yogi T,Tsutumi H,Fujiyoshi T,Sato T,Hieda N,Yoshida T,Okuno N,Shimizu Y,Yatabe Y,Niwa Y,Yamao K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to determine if pancreatic neuroendocrine carcinomas are accurately characterized by the WHO 2010 classification of pancreatic neuroendocrine neoplasms</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25645959"> <div itemprop="name">Multifunctional ultrasmall nanoplatforms for vascular-targeted interstitial photodynamic therapy of brain tumors guided by real-time MRI.</div> </a> <div itemprop="about">Nanomedicine : nanotechnology, biology, and medicine</div> <div itemprop="author">Bechet D,Auger F,Couleaud P,Marty E,Ravasi L,Durieux N,Bonnet C,Plénat F,Frochot C,Mordon S,Tillement O,Vanderesse R,Lux F,Perriat P,Guillemin F,Barberi-Heyob M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to provide in vivo proof of principle for the use of closed-head iPDT guided by real-time MRI using targeted ultra small nanoplatforms</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25637316"> <div itemprop="name">IKKβ Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Kinose Y,Sawada K,Makino H,Ogura T,Mizuno T,Suzuki N,Fujikawa T,Morii E,Nakamura K,Sawada I,Toda A,Hashimoto K,Isobe A,Mabuchi S,Ohta T,Itai A,Morishige K,Kurachi H,Kimura T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study the role of IKKbeta during ovarian cancer angiogenesis</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25381264"> <div itemprop="name">Combination strategy targeting VEGF and HGF/c-met in human renal cell carcinoma models.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Ciamporcero E,Miles KM,Adelaiye R,Ramakrishnan S,Shen L,Ku S,Pizzimenti S,Sennino B,Barrera G,Pili R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to determine the effects of targeting the VEGF and c-met pathways in clear cell renal cell carcinoma models.</div> <div itemprodp="datePublished">Thu Jan 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25820592"> <div itemprop="name">Retrospective analysis of metastatic behaviour of breast cancer subtypes.</div> </a> <div itemprop="about">Breast cancer research and treatment</div> <div itemprop="author">Savci-Heijink CD,Halfwerk H,Hooijer GK,Horlings HM,Wesseling J,van de Vijver MJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to analyze breast cancer subtypes and retrospective analysis of metastatic behaviour</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25620586"> <div itemprop="name">The effect of pomegranate fruit extract on testosterone-induced BPH in rats.</div> </a> <div itemprop="about">The Prostate</div> <div itemprop="author">Ammar AE,Esmat A,Hassona MD,Tadros MG,Abdel-Naim AB,Guns ES</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study the effect of Pomegranate Fruit Extract (PFE) in a testosterone-induced benign prostatic hyperplasia model</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25454731"> <div itemprop="name">Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy.</div> </a> <div itemprop="about">Neuromuscular disorders : NMD</div> <div itemprop="author">Meinke P,Schneiderat P,Srsen V,Korfali N,Lê Thành P,Cowan GJ,Cavanagh DR,Wehnert M,Schirmer EC,Walter MC</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to use of a myoblasts from a symptomatic female carrier of X-linnked Emery-Dreifuss muscular dystrophy to study abnormal proliferation and spontaneous differentiation</div> <div itemprodp="datePublished">Sun Feb 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25466465"> <div itemprop="name">Primary intraosseous hybrid nerve sheath tumor of femur: a hitherto undescribed occurrence in bone with secondary aneurysmal bone cyst formation resulting in pathological fracture.</div> </a> <div itemprop="about">Pathology, research and practice</div> <div itemprop="author">Chow LT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to characterize first case of primary intraosseous hybrid nerve sheath tumor</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26436086"> <div itemprop="name">Missense Mutations in Exons 18-24 of EGFR in Hepatocellular Carcinoma Tissues.</div> </a> <div itemprop="about">BioMed research international</div> <div itemprop="author">Panvichian R,Tantiwetrueangdet A,Sornmayura P,Leelaudomlipi S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to characterize hepatocellular carcinoma tissues and missense mutations in exons 18-24 of EGFR</div> <div itemprodp="datePublished">Tue Jul 19 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26429178"> <div itemprop="name">A challenging case of ocular melanoma.</div> </a> <div itemprop="about">Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie</div> <div itemprop="author">Costache M,Dumitru AV,Pătraşcu OM,Popa-Cherecheanu DA,Bădilă P,Miu JC,Procop A,Popa M,Tampa MŞ,Sajin M,Simionescu O,Cîrstoiu MM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to present a case of highly aggressive ocular melanoma</div> <div itemprodp="datePublished">Tue May 10 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25920185"> <div itemprop="name">P16(INK 4a) and Ki-67 expression in human papilloma virus-related head and neck mucosal lesions.</div> </a> <div itemprop="about">Investigacion clinica</div> <div itemprop="author">Gültekin SE,Sengüven B,Klussmann JP,Dienes HP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to determine the potential role of p16(INK 4a) and Ki-67 expression in human papilloma virus-related lesions</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25887251"> <div itemprop="name">Site-specific programming of the host epithelial transcriptome by the gut microbiota.</div> </a> <div itemprop="about">Genome biology</div> <div itemprop="author">Sommer F,Nookaew I,Sommer N,Fogelstrand P,Bäckhed F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to examine microbiota-induced transcriptional responses in specific fractions of intestinal epithelial cells.</div> <div itemprodp="datePublished">Sat Mar 28 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26134322"> <div itemprop="name">Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish.</div> </a> <div itemprop="about">PLoS genetics</div> <div itemprop="author">Evason KJ,Francisco MT,Juric V,Balakrishnan S,Lopez Pazmino Mdel P,Gordan JD,Kakar S,Spitsbergen J,Goga A,Stainier DY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to assess beta-catenin-driven liver tumorigenesis in zebrafish by indentifying chemical inhibitors</div> <div itemprodp="datePublished">Wed Jul 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25766884"> <div itemprop="name">In vivo imaging of cell proliferation for a dynamic, whole body, analysis of undesired drug effects.</div> </a> <div itemprop="about">Toxicological sciences : an official journal of the Society of Toxicology</div> <div itemprop="author">Rizzi N,Manni I,Vantaggiato C,Delledonne GA,Gentileschi MP,Maggi A,Piaggio G,Ciana P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to image cell proliferation in vivo in a non-invasive fashion to investigate undesired drug effects</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26212322"> <div itemprop="name">miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability.</div> </a> <div itemprop="about">Cell reports</div> <div itemprop="author">Parchem RJ,Moore N,Fish JL,Parchem JG,Braga TT,Shenoy A,Oldham MC,Rubenstein JL,Schneider RA,Blelloch R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to characterize the timing of neural tube closure, embryonic viability, and neural differentiation by the required miR-302</div> <div itemprodp="datePublished">Tue Aug 04 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25826681"> <div itemprop="name">Appropriateness of using patient-derived xenograft models for pharmacologic evaluation of novel therapies for esophageal/gastro-esophageal junction cancers.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Dodbiba L,Teichman J,Fleet A,Thai H,Starmans MH,Navab R,Chen Z,Girgis H,Eng L,Espin-Garcia O,Shen X,Bandarchi B,Schwock J,Tsao MS,El-Zimaity H,Der SD,Xu W,Bristow RG,Darling GE,Boutros PC,Ailles LE,Liu G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to use of xenograft models from patients to evaluate pharmacologic therapies for esophageal/gastro-esophageal junction cancers</div> <div itemprodp="datePublished">Sun Mar 27 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25937372"> <div itemprop="name">Castration-resistant Lgr5(+) cells are long-lived stem cells required for prostatic regeneration.</div> </a> <div itemprop="about">Stem cell reports</div> <div itemprop="author">Wang BE,Wang X,Long JE,Eastham-Anderson J,Firestein R,Junttila MR</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to identify G-protein-coupled receptor 5 (Lgr5) expression in prostate epithelial progenitor cells</div> <div itemprodp="datePublished">Tue May 12 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/26041878"> <div itemprop="name">Patient-derived bladder cancer xenografts in the preclinical development of novel targeted therapies.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Jäger W,Xue H,Hayashi T,Janssen C,Awrey S,Wyatt AW,Anderson S,Moskalev I,Haegert A,Alshalalfa M,Erho N,Davicioni E,Fazli L,Li E,Collins C,Wang Y,Black PC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to develop and characterize patient-derived primary xenografts to a model of muscle invasive bladder cancer.</div> <div itemprodp="datePublished">Fri Aug 28 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25826270"> <div itemprop="name">A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Malchenko S,Sredni ST,Hashimoto H,Kasai A,Nagayasu K,Xie J,Margaryan NV,Seiriki K,Lulla RR,Seftor RE,Pachman LM,Meltzer HY,Hendrix MJ,Soares MB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to describe a mouse model to study primitive neuroectodermal tumors</div> <div itemprodp="datePublished">Sun Mar 27 00:00:00 EDT 2016</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25547823"> <div itemprop="name">Oral squamous cell carcinoma associated with proliferative verrucous leukoplakia compared with conventional squamous cell carcinoma--a clinical, histologic and immunohistochemical study.</div> </a> <div itemprop="about">Oral surgery, oral medicine, oral pathology and oral radiology</div> <div itemprop="author">Akrish S,Ben-Izhak O,Sabo E,Rachmiel A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to compare the features of patients with proliferative verrucous leukoplakia and those with conventional squamous cell carcinoma</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24705253"> <div itemprop="name">De novo CCND2 mutations leading to stabilization of cyclin D2 cause megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome.</div> </a> <div itemprop="about">Nature genetics</div> <div itemprop="author">Mirzaa G,Parry DA,Fry AE,Giamanco KA,Schwartzentruber J,Vanstone M,Logan CV,Roberts N,Johnson CA,Singh S,Kholmanskikh SS,Adams C,Hodge RD,Hevner RF,Bonthron DT,Braun KPJ,Faivre L,Rivière JB,St-Onge J,Gripp KW,Mancini GM,Pang K,Sweeney E,van Esch H,Verbeek N,Wieczorek D,Steinraths M,Majewski J,Boycot KM,Pilz DT,Ross ME,Dobyns WB,Sheridan EG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to discover how de novo mutations of CCND2 lead to cyclin D2 stabilization and megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24462734"> <div itemprop="name">Fascin is regulated by slug, promotes progression of pancreatic cancer in mice, and is associated with patient outcomes.</div> </a> <div itemprop="about">Gastroenterology</div> <div itemprop="author">Li A,Morton JP,Ma Y,Karim SA,Zhou Y,Faller WJ,Woodham EF,Morris HT,Stevenson RP,Juin A,Jamieson NB,MacKay CJ,Carter CR,Leung HY,Yamashiro S,Blyth K,Sansom OJ,Machesky LM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate the prognostic value of fascin in pancreatic cancer</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24012615"> <div itemprop="name">AMPKα1 controls hepatocyte proliferation independently of energy balance by regulating Cyclin A2 expression.</div> </a> <div itemprop="about">Journal of hepatology</div> <div itemprop="author">Merlen G,Gentric G,Celton-Morizur S,Foretz M,Guidotti JE,Fauveau V,Leclerc J,Viollet B,Desdouets C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of cyclin D2 in the energy balance-independent modulation of hepatocyte proliferation by AMPK-alpha1</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24401275"> <div itemprop="name">MNK1 pathway activity maintains protein synthesis in rapalog-treated gliomas.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Grzmil M,Huber RM,Hess D,Frank S,Hynx D,Moncayo G,Klein D,Merlo A,Hemmings BA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry and western blot to study the mechanism by which the MNK1 pathway maintains protein synthetic activity in glioma cells treated with rapamycin analogs</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24768046"> <div itemprop="name">Constructs of electrospun PLGA, compressed collagen and minced urothelium for minimally manipulated autologous bladder tissue expansion.</div> </a> <div itemprop="about">Biomaterials</div> <div itemprop="author">Ajalloueian F,Zeiai S,Fossum M,Hilborn JG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop a system for the expansion of autologous bladder tissue based on the use of electrospun PLGA, compressed collagen and minced urothelium</div> <div itemprodp="datePublished">Tue Jul 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24854271"> <div itemprop="name">The kidney is the principal organ mediating klotho effects.</div> </a> <div itemprop="about">Journal of the American Society of Nephrology : JASN</div> <div itemprop="author">Lindberg K,Amin R,Moe OW,Hu MC,Erben RG,Östman Wernerson A,Lanske B,Olauson H,Larsson TE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section report the kidney is the principal contributor of circulating Klotho and regulates anti-aging traits</div> <div itemprodp="datePublished">Wed Oct 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24500694"> <div itemprop="name">Contrasting responses of non-small cell lung cancer to antiangiogenic therapies depend on histological subtype.</div> </a> <div itemprop="about">EMBO molecular medicine</div> <div itemprop="author">Larrayoz M,Pio R,Pajares MJ,Zudaire I,Ajona D,Casanovas O,Montuenga LM,Agorreta J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the response of different histological sub-types of non-small cell lung cancer to anti-angiogenic therapy</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24789034"> <div itemprop="name">Mesenchymal stem cells from human fat engineered to secrete BMP4 are nononcogenic, suppress brain cancer, and prolong survival.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Li Q,Wijesekera O,Salas SJ,Wang JY,Zhu M,Aprhys C,Chaichana KL,Chesler DA,Zhang H,Smith CL,Guerrero-Cazares H,Levchenko A,Quinones-Hinojosa A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate the therapeutic potential of engineered mesenchymal stem cells from human fat for glioblastoma</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24934810"> <div itemprop="name">MYC synergizes with activated BRAFV600E in mouse lung tumor development by suppressing senescence.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Tabor V,Bocci M,Alikhani N,Kuiper R,Larsson LG</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to examine the role of MYC during tumor development in vivo</div> <div itemprodp="datePublished">Fri Aug 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24305876"> <div itemprop="name">FGFR1-WNT-TGF-β signaling in prostate cancer mouse models recapitulates human reactive stroma.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Carstens JL,Shahi P,Van Tsang S,Smith B,Creighton CJ,Zhang Y,Seamans A,Seethammagari M,Vedula I,Levitt JM,Ittmann MM,Rowley DR,Spencer DM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to use transgenic murine models to esablish the key role of the FGR1-Wnt-TGF-beta signaling axis in prostate cancer reactive stroma</div> <div itemprodp="datePublished">Wed Jan 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24322980"> <div itemprop="name">Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Hoos A,Protsyuk D,Borsig L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of PSGL-1 in the recruitment of monocytes to sites of metastasis</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24371225"> <div itemprop="name">Phosphorylation at Ser-181 of oncogenic KRAS is required for tumor growth.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Barceló C,Paco N,Morell M,Alvarez-Moya B,Bota-Rabassedas N,Jaumot M,Vilardell F,Capella G,Agell N</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of serine 181 phosphorylation in the ocogenic properties of KRAS</div> <div itemprodp="datePublished">Sat Feb 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24638982"> <div itemprop="name">Myeloid WNT7b mediates the angiogenic switch and metastasis in breast cancer.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Yeo EJ,Cassetta L,Qian BZ,Lewkowich I,Li JF,Stefater JA,Smith AN,Wiechmann LS,Wang Y,Pollard JW,Lang RA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the angiogenic switch and metastatic progression of breast cancer and the role of myeloid cell WNT7b</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24532687"> <div itemprop="name">A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.</div> </a> <div itemprop="about">Genes & development</div> <div itemprop="author">Okada N,Lin CP,Ribeiro MC,Biton A,Lai G,He X,Bu P,Vogel H,Jablons DM,Keller AC,Wilkinson JE,He B,Speed TP,He L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of a p53-miRNA-34 positive-feedback loop in tumor suppression in lung cancer</div> <div itemprodp="datePublished">Sat Mar 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25228645"> <div itemprop="name">ZNF750 interacts with KLF4 and RCOR1, KDM1A, and CTBP1/2 chromatin regulators to repress epidermal progenitor genes and induce differentiation genes.</div> </a> <div itemprop="about">Genes & development</div> <div itemprop="author">Boxer LD,Barajas B,Tao S,Zhang J,Khavari PA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to characterize the transcription factor ZNF750.</div> <div itemprodp="datePublished">Mon Sep 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24147912"> <div itemprop="name">Chronic melatonin treatment rescues electrophysiological and neuromorphological deficits in a mouse model of Down syndrome.</div> </a> <div itemprop="about">Journal of pineal research</div> <div itemprop="author">Corrales A,Vidal R,García S,Vidal V,Martínez P,García E,Flórez J,Sanchez-Barceló EJ,Martínez-Cué C,Rueda N</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of increased neurogenesis and normalization of electrophysiology in the therapeutic effects of melatonin in a murine model of Down syndrome</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24200746"> <div itemprop="name">Controlled delivery of fibroblast growth factor-1 and neuregulin-1 from biodegradable microparticles promotes cardiac repair in a rat myocardial infarction model through activation of endogenous regeneration.</div> </a> <div itemprop="about">Journal of controlled release : official journal of the Controlled Release Society</div> <div itemprop="author">Formiga FR,Pelacho B,Garbayo E,Imbuluzqueta I,Díaz-Herráez P,Abizanda G,Gavira JJ,Simón-Yarza T,Albiasu E,Tamayo E,Prósper F,Blanco-Prieto MJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to characterize endogenous regeneration induced by fibroblast growth factor-1 and neuregulin-1</div> <div itemprodp="datePublished">Fri Jan 10 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24859880"> <div itemprop="name">SIGLEC-G deficiency increases susceptibility to develop B-cell lymphoproliferative disorders.</div> </a> <div itemprop="about">Haematologica</div> <div itemprop="author">Simonetti G,Bertilaccio MT,Rodriguez TV,Apollonio B,Dagklis A,Rocchi M,Innocenzi A,Casola S,Winkler TH,Nitschke L,Ponzoni M,Caligaris-Cappio F,Ghia P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the increased incidence of B-cell lymphoproliferative disorders in Siglecg (-/-) mice</div> <div itemprodp="datePublished">Fri Aug 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24218309"> <div itemprop="name">Evaluation of Ki-67 index in EUS-FNA specimens for the assessment of malignancy risk in pancreatic neuroendocrine tumors.</div> </a> <div itemprop="about">Endoscopy</div> <div itemprop="author">Hasegawa T,Yamao K,Hijioka S,Bhatia V,Mizuno N,Hara K,Imaoka H,Niwa Y,Tajika M,Kondo S,Tanaka T,Shimizu Y,Kinoshita T,Kohsaki T,Nishimori I,Iwasaki S,Saibara T,Hosoda W,Yatabe Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the malignancy risk of pancreatic neuroendocrine tumors based on the Ki67 index of endoscopic ultrasound-guided fine-needle aspiration samples</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24130333"> <div itemprop="name">G0-G1 transition and the restriction point in pancreatic β-cells in vivo.</div> </a> <div itemprop="about">Diabetes</div> <div itemprop="author">Hija A,Salpeter S,Klochendler A,Grimsby J,Brandeis M,Glaser B,Dor Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the cell-cycle kinetics of the pancreatic beta-cell and the restriction point at the Go-G1 transition</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24155265"> <div itemprop="name">Contribution of mesenchymal proliferation in tooth root morphogenesis.</div> </a> <div itemprop="about">Journal of dental research</div> <div itemprop="author">Sohn WJ,Choi MA,Yamamoto H,Lee S,Lee Y,Jung JK,Jin MU,An CH,Jung HS,Suh JY,Shin HI,Kim JY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of mesenchymal proliferation in the morphogenesis of the tooth root</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24662815"> <div itemprop="name">The kinetics of ER fusion protein activation in vivo.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Wilson CH,Gamper I,Perfetto A,Auw J,Littlewood TD,Evan GI</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to determine the best route of delivery of 4-hydroxytamoxifen for the in vivo activation of estrogen receptor fusion proteins</div> <div itemprodp="datePublished">Thu Oct 02 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24382117"> <div itemprop="name">Differentiation and histogenesis of syringomatous tumour of the nipple and low-grade adenosquamous carcinoma: evidence for a common origin.</div> </a> <div itemprop="about">Histopathology</div> <div itemprop="author">Boecker W,Stenman G,Loening T,Andersson MK,Sinn HP,Barth P,Oberhellmann F,Bos I,Berg T,Marusic Z,Samoilova V,Buchwalow I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the potential common origin of syringomatous tumor of the nipple and low-grade adenosquamous carcinoma of the breast</div> <div itemprodp="datePublished">Tue Jul 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24771207"> <div itemprop="name">Temsirolimus combined with cisplatin or bevacizumab is active in osteosarcoma models.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Fleuren ED,Versleijen-Jonkers YM,Roeffen MH,Franssen GM,Flucke UE,Houghton PJ,Oyen WJ,Boerman OC,van der Graaf WT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the efficacy of combination therapy with the mTOR inhibitor temsirolimus plus either cisplatin or bevacizumab in xenograft models of osteosarcoma</div> <div itemprodp="datePublished">Mon Dec 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24436106"> <div itemprop="name">Protease-activated receptor-1 drives pancreatic cancer progression and chemoresistance.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Queiroz KC,Shi K,Duitman J,Aberson HL,Wilmink JW,van Noesel CJ,Richel DJ,Spek CA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study pancreatic cancer and the role of PAR-1 in progression and chemoresistance</div> <div itemprodp="datePublished">Sat Nov 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23893655"> <div itemprop="name">Tumor vascularization is critical for oncolytic vaccinia virus treatment of peritoneal carcinomatosis.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Ottolino-Perry K,Tang N,Head R,Ng C,Arulanandam R,Angarita FA,Acuna SA,Chen Y,Bell J,Dacosta RS,McCart JA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of an oncolytic vaccina virus against peritoneal carcinomatosis and the key role of a diseminated tumor vasculature for therapeutic efficacy</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24825316"> <div itemprop="name">High stress hormone levels accelerate the onset of memory deficits in male Huntington's disease mice.</div> </a> <div itemprop="about">Neurobiology of disease</div> <div itemprop="author">Mo C,Pang TY,Ransome MI,Hill RA,Renoir T,Hannan AJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms underlying the accelerated development of memory impairment in male Huntington's disease mice in response to elevated stress hormone levels</div> <div itemprodp="datePublished">Mon Sep 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24872566"> <div itemprop="name">Overexpression of the astrocyte glutamate transporter GLT1 exacerbates phrenic motor neuron degeneration, diaphragm compromise, and forelimb motor dysfunction following cervical contusion spinal cord injury.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Li K,Nicaise C,Sannie D,Hala TJ,Javed E,Parker JL,Putatunda R,Regan KA,Suain V,Brion JP,Rhoderick F,Wright MC,Poulsen DJ,Lepore AC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the deleterious effects of astrocyte GLT1 overexpression on cervical contusion spinal cord injury-induced neuronal damage and respiratory impairment</div> <div itemprodp="datePublished">Wed May 28 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25319698"> <div itemprop="name">Characterization of ectopic colonies that form in widespread areas of the nervous system with neural stem cell transplants into the site of a severe spinal cord injury.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Steward O,Sharp KG,Yee KM,Hatch MN,Bonner JF</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to characterize the incidence, distribution, and cellular composition of the ectopic colonies arising from transplanted fetal neuronal stem cells in the nervous system</div> <div itemprodp="datePublished">Wed Oct 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23657974"> <div itemprop="name">Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells.</div> </a> <div itemprop="about">The journals of gerontology. Series A, Biological sciences and medical sciences</div> <div itemprop="author">Mitterberger MC,Lechner S,Mattesich M,Zwerschke W</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the reduced adipogenic differentiation potential of human subcutaneous adipose-derived stromal/progenitor cells that have entered replicative senescence following prolonged culture</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24723451"> <div itemprop="name">Culture dimensionality influences the resistance of glioblastoma stem-like cells to multikinase inhibitors.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Fernandez-Fuente G,Mollinedo P,Grande L,Vazquez-Barquero A,Fernandez-Luna JL</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the sensitivity of glioblastoma stem-like cells to multi-kinase inhbitors and the effect of 2-D versus 3-D culture</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25219356"> <div itemprop="name">WFDC1 is a key modulator of inflammatory and wound repair responses.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Ressler SJ,Dang TD,Wu SM,Tse DY,Gilbert BE,Vyakarnam A,Yang F,Schauer IG,Barron DA,Rowley DR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of WDC1 during infection and wound healing using wdc1-null mice</div> <div itemprodp="datePublished">Sat Nov 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25193592"> <div itemprop="name">Prolactin-induced prostate tumorigenesis links sustained Stat5 signaling with the amplification of basal/stem cells and emergence of putative luminal progenitors.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Sackmann-Sala L,Chiche A,Mosquera-Garrote N,Boutillon F,Cordier C,Pourmir I,Pascual-Mathey L,Kessal K,Pigat N,Camparo P,Goffin V</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study the role of prolactin and STAT5 during early prostate tumorigenesis</div> <div itemprodp="datePublished">Sat Nov 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24626992"> <div itemprop="name">RUNX2 correlates with subtype-specific breast cancer in a human tissue microarray, and ectopic expression of Runx2 perturbs differentiation in the mouse mammary gland.</div> </a> <div itemprop="about">Disease models & mechanisms</div> <div itemprop="author">McDonald L,Ferrari N,Terry A,Bell M,Mohammed ZM,Orange C,Jenkins A,Muller WJ,Gusterson BA,Neil JC,Edwards J,Morris JS,Cameron ER,Blyth K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the association of high levels of RUNX2 expression with ER/PR/HER2-negative breast cancers and the role of elevated RUNX2 in promoting mammary epithelial neoplastic changes</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25202271"> <div itemprop="name">n-3 polyunsaturated fatty acids supplementation enhances hippocampal functionality in aged mice.</div> </a> <div itemprop="about">Frontiers in aging neuroscience</div> <div itemprop="author">Cutuli D,De Bartolo P,Caporali P,Laricchiuta D,Foti F,Ronci M,Rossi C,Neri C,Spalletta G,Caltagirone C,Farioli-Vecchioli S,Petrosini L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the positive neuroprotective effects from omega-3 polyunsaturated acid supplementation</div> <div itemprodp="datePublished">Tue Sep 09 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24247561"> <div itemprop="name">CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy.</div> </a> <div itemprop="about">Laboratory investigation; a journal of technical methods and pathology</div> <div itemprop="author">Duitman J,Borensztajn KS,Pulskens WP,Leemans JC,Florquin S,Spek CA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study chronic obstructive nephropathy and the role of C/EBP-delta in modulating tubular damage and interstitial fibrosis</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24462502"> <div itemprop="name">Activation of cutaneous immune responses in complex regional pain syndrome.</div> </a> <div itemprop="about">The journal of pain</div> <div itemprop="author">Birklein F,Drummond PD,Li W,Schlereth T,Albrecht N,Finch PM,Dawson LF,Clark JD,Kingery WS</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study cell proliferation and the cellular source of inflammatory mediators in complex regional pain syndrome using a rat fracture model</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24572875"> <div itemprop="name">Degeneration, regeneration, and cicatrization after fat grafting: dynamic total tissue remodeling during the first 3 months.</div> </a> <div itemprop="about">Plastic and reconstructive surgery</div> <div itemprop="author">Kato H,Mineda K,Eto H,Doi K,Kuno S,Kinoshita K,Kanayama K,Yoshimura K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the dynamics of fat remodeling following surgical grafting</div> <div itemprodp="datePublished">Sat Mar 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23236211"> <div itemprop="name">Dysfunction of KCNK potassium channels impairs neuronal migration in the developing mouse cerebral cortex.</div> </a> <div itemprop="about">Cerebral cortex (New York, N.Y. : 1991)</div> <div itemprop="author">Bando Y,Hirano T,Tagawa Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study impaired cerebral cortical migration of neurones in developing mice following knockdown of various KCNK potassium channels</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24718936"> <div itemprop="name">GPER mediates estrogen-induced signaling and proliferation in human breast epithelial cells and normal and malignant breast.</div> </a> <div itemprop="about">Hormones & cancer</div> <div itemprop="author">Scaling AL,Prossnitz ER,Hathaway HJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study estrogen-induced breast epithelial cell proliferation in normal and malignant breast tissue and the involvement of GPER</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24243624"> <div itemprop="name">A disintegrin and metalloproteinase 12 (ADAM12) localizes to invasive trophoblast, promotes cell invasion and directs column outgrowth in early placental development.</div> </a> <div itemprop="about">Molecular human reproduction</div> <div itemprop="author">Aghababaei M,Perdu S,Irvine K,Beristain AG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of trophoblast-localized ADAM12 in early placental development</div> <div itemprodp="datePublished">Sat Mar 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24803261"> <div itemprop="name">Diverse roles for Wnt7a in ventral midbrain neurogenesis and dopaminergic axon morphogenesis.</div> </a> <div itemprop="about">Stem cells and development</div> <div itemprop="author">Fernando CV,Kele J,Bye CR,Niclis JC,Alsanie W,Blakely BD,Stenman J,Turner BJ,Parish CL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study ventral midbrain neurogenesis and the growth of dopaminergic axons, and the modulatory roles played by the secreted glycoprotein Wnt7a</div> <div itemprodp="datePublished">Mon Sep 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24550213"> <div itemprop="name">Ex vivo culture of primary human colonic tissue for studying transcriptional responses to 1α,25(OH)2 and 25(OH) vitamin D.</div> </a> <div itemprop="about">Physiological genomics</div> <div itemprop="author">Mapes B,Chase M,Hong E,Ludvik A,Ceryes K,Huang Y,Kupfer SS</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the transcriptional responses to vitamin D using an ex vivo primary human colon tissue model system</div> <div itemprodp="datePublished">Tue Apr 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24657831"> <div itemprop="name">Histone deacetylase expression in white matter oligodendrocytes after stroke.</div> </a> <div itemprop="about">Neurochemistry international</div> <div itemprop="author">Kassis H,Chopp M,Liu XS,Shehadah A,Roberts C,Zhang ZG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to measure the expression of individual HDACs in the oligodendrocyte lineage during stroke-induced oligodendrogenesis</div> <div itemprodp="datePublished">Sat Nov 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24613255"> <div itemprop="name">Distribution pattern of the Ki67 labelling index in breast cancer and its implications for choosing cut-off values.</div> </a> <div itemprop="about">Breast (Edinburgh, Scotland)</div> <div itemprop="author">Cserni G,Vörös A,Liepniece-Karele I,Bianchi S,Vezzosi V,Grabau D,Sapino A,Castellano I,Regitnig P,Foschini MP,Zolota V,Varga Z,Figueiredo P,Decker T,Focke C,Kulka J,Kaya H,Reiner-Concin A,Amendoeira I,Callagy G,Caffrey E,Wesseling J,Wells C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study Ki labelling index in breast cancer samples with respect to the appropriateness of cut-off values used to diagnose tumors with low and high proliferative capacity</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24152580"> <div itemprop="name">Therapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver.</div> </a> <div itemprop="about">Gene therapy</div> <div itemprop="author">Maczuga P,Verheij J,van der Loos C,van Logtenstein R,Hooijer G,Martier R,Borel F,Lubelski J,Koornneef A,Blits B,van Deventer S,Petry H,Konstantinova P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of short hairpin-mediated knockdown of hepatic ApoB100 and the associated phentypic and gene expression changes</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24315958"> <div itemprop="name">P53-participated cellular and molecular responses to irradiation are cell differentiation-determined in murine intestinal epithelium.</div> </a> <div itemprop="about">Archives of biochemistry and biophysics</div> <div itemprop="author">Wang F,Cheng J,Liu D,Sun H,Zhao J,Wang J,Chen J,Su Y,Zou Z</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of differentiation status on the responses of murine epithelial cells to irradiation</div> <div itemprodp="datePublished">Wed Jan 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24647714"> <div itemprop="name">Cells of renin lineage take on a podocyte phenotype in aging nephropathy.</div> </a> <div itemprop="about">American journal of physiology. Renal physiology</div> <div itemprop="author">Pippin JW,Glenn ST,Krofft RD,Rusiniak ME,Alpers CE,Hudkins K,Duffield JS,Gross KW,Shankland SJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study podocyte depletion in aging nephropathy and the ability of renin lineage cells to adopt a podocyte phenotype</div> <div itemprodp="datePublished">Thu May 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23461397"> <div itemprop="name">μ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche.</div> </a> <div itemprop="about">Addiction biology</div> <div itemprop="author">Contet C,Kim A,Le D,Iyengar SK,Kotzebue RW,Yuan CJ,Kieffer BL,Mandyam CD</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the mu-opioid receptor in the effects of chronic ethanol consumption on dentate gyrus neuroplasticity</div> <div itemprodp="datePublished">Mon Sep 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24713393"> <div itemprop="name">The small GTPase Rheb is required for spermatogenesis but not oogenesis.</div> </a> <div itemprop="about">Reproduction (Cambridge, England)</div> <div itemprop="author">Baker MD,Ezzati M,Aloisio GM,Tarnawa ED,Cuevas I,Nakada Y,Castrillon DH</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to use conditional knockout mice to study the spermatogenic role of the Rhab small GTPase and its lack of corresponding involvement in oogenesis</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24020724"> <div itemprop="name">High-risk human papillomavirus load and biomarkers in cervical intraepithelial neoplasia and cancer.</div> </a> <div itemprop="about">APMIS : acta pathologica, microbiologica, et immunologica Scandinavica</div> <div itemprop="author">Chang MS,Oh S,Jung EJ,Park JH,Jeon HW,Lee TS,Kim JH,Choi E,Byeon SJ,Park IA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the relationships between high risk HPV load, the expression of various biomarkers, and cervical intraepithelial neoplasia and cancer</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24814255"> <div itemprop="name">MET expression is associated with disease-specific survival in breast cancer patients in the neoadjuvant setting.</div> </a> <div itemprop="about">Pathology, research and practice</div> <div itemprop="author">Koh YW,Lee HJ,Ahn JH,Lee JW,Gong G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the prognostic value of MET expression in breast cancer patienrs receiving neoadjuvant chemotherapy</div> <div itemprodp="datePublished">Fri Aug 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23963898"> <div itemprop="name">Immunohistochemical distribution of cell cycle proteins p27, p57, cyclin D3, PCNA and Ki67 in normal and diabetic human placentas.</div> </a> <div itemprop="about">Journal of molecular histology</div> <div itemprop="author">Unek G,Ozmen A,Mendilcioglu I,Simsek M,Korgun ET</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine human placentas from control and diabetic subjects for the immunohistochemical localization of a number of cell cycle related proteins</div> <div itemprodp="datePublished">Sat Feb 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24576537"> <div itemprop="name">CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways.</div> </a> <div itemprop="about">Developmental biology</div> <div itemprop="author">Saba R,Wu Q,Saga Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the suppression of STRA8-dependent and -independent pathways in the mechanism by which CYP26B1 promotes the differentiation of male germ cells</div> <div itemprodp="datePublished">Thu May 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24183939"> <div itemprop="name">NANOS2 promotes male germ cell development independent of meiosis suppression.</div> </a> <div itemprop="about">Developmental biology</div> <div itemprop="author">Saba R,Kato Y,Saga Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism underlying the role in male germ cell development of the NANOS2 RNA-binding protein</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23861145"> <div itemprop="name">Birthdating of myenteric neuron subtypes in the small intestine of the mouse.</div> </a> <div itemprop="about">The Journal of comparative neurology</div> <div itemprop="author">Bergner AJ,Stamp LA,Gonsalvez DG,Allison MB,Olson DP,Myers MG,Anderson CR,Young HM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to determine when murine small intestine myenteric neuron subtypes are born</div> <div itemprodp="datePublished">Sat Feb 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24852133"> <div itemprop="name">The expression of cell cycle related proteins PCNA, Ki67, p27 and p57 in normal and preeclamptic human placentas.</div> </a> <div itemprop="about">Tissue & cell</div> <div itemprop="author">Unek G,Ozmen A,Mendilcioglu I,Simsek M,Korgun ET</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine human placentas from normal and preeclampsic pregnancies for the expression of PCNA, Ki67 and p57</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24443274"> <div itemprop="name">Bronchiolar remodeling in adult mice following neonatal exposure to hyperoxia: relation to growth.</div> </a> <div itemprop="about">Anatomical record (Hoboken, N.J. : 2007)</div> <div itemprop="author">O'Reilly M,Hansbro PM,Horvat JC,Beckett EL,Harding R,Sozo F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study hyperoxia in neonatal bronchioles</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24252562"> <div itemprop="name">Immunolocalization of cell cycle proteins (p57, p27, cyclin D3, PCNA and Ki67) in intrauterine growth retardation (IUGR) and normal human term placentas.</div> </a> <div itemprop="about">Acta histochemica</div> <div itemprop="author">Unek G,Ozmen A,Ozekinci M,Sakinci M,Korgun ET</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to perform a comparative study of intrauterine growth retardation and normal human term placentas in respect of the expression and localization of p57, p27, cyclin D3, PCNA and Ki67</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24176105"> <div itemprop="name">Solitary tumours associated with Jaagsiekte retrovirus in sheep are heterogeneous and contain cells expressing markers identifying progenitor cells in lung repair.</div> </a> <div itemprop="about">Journal of comparative pathology</div> <div itemprop="author">De las Heras M,de Martino A,Borobia M,Ortín A,Álvarez R,Borderías L,Giménez-Más JA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the heterogeneity and the presence of lung repair progenitor cells in Jaagsiekte retrovirus-associated solitary tumors in sheep</div> <div itemprodp="datePublished">Tue Nov 18 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24853430"> <div itemprop="name">Non-viral FoxM1 gene delivery to hepatocytes enhances liver repopulation.</div> </a> <div itemprop="about">Cell death & disease</div> <div itemprop="author">Xiang D,Liu CC,Wang MJ,Li JX,Chen F,Yao H,Yu B,Lu L,Borjigin U,Chen YX,Zhong L,Wangensteen KJ,He ZY,Wang X,Hu YP</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the enhanced proliferative and liver repopulation capacity of hepatocytes following transposon vector delivery of the FoxM1 gene</div> <div itemprodp="datePublished">Thu May 22 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24573392"> <div itemprop="name">Renal tubular Notch signaling triggers a prosenescent state after acute kidney injury.</div> </a> <div itemprop="about">American journal of physiology. Renal physiology</div> <div itemprop="author">Sörensen-Zender I,Rong S,Susnik N,Zender S,Pennekamp P,Melk A,Haller H,Schmitt R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the promotion of a pro-senescent state by tubular epithelial Notch signaling following kidney ischemia-reperfusion injury</div> <div itemprodp="datePublished">Tue Apr 15 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24759995"> <div itemprop="name">Effects of siRNA on RET/PTC3 junction oncogene in papillary thyroid carcinoma: from molecular and cellular studies to preclinical investigations.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Ali HM,Urbinati G,Chapuis H,Desmaele D,Bertrand JR,Couvreur P,Massaad-Massade L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the therapeutic effects against papillary thyroid carcinoma of siRNA-mediated knockdown of RET/PTC3 junction oncogene in cellular and murine models</div> <div itemprodp="datePublished">Fri Jun 19 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24453992"> <div itemprop="name">Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma.</div> </a> <div itemprop="about">PLoS genetics</div> <div itemprop="author">Kikuchi K,Hettmer S,Aslam MI,Michalek JE,Laub W,Wilky BA,Loeb DM,Rubin BP,Wagers AJ,Keller C</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to investigate regulation of the Pax3:Foxo1a locus in cancer cells</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24454932"> <div itemprop="name">Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Pulskens WP,Butter LM,Teske GJ,Claessen N,Dessing MC,Flavell RA,Sutterwala FS,Florquin S,Leemans JC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the non-canonical role of the Nlrp3 inflammasome in protecting against renal interstitial edema and increased vascular permeability following unilateral ureteral obstruction</div> <div itemprodp="datePublished">Sun Sep 21 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24788190"> <div itemprop="name">Influence of oxygen tension on dopaminergic differentiation of human fetal stem cells of midbrain and forebrain origin.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Krabbe C,Bak ST,Jensen P,von Linstow C,Martínez Serrano A,Hansen C,Meyer M</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study human fetal midbrain and forebrain stem cells and the effect of oxygen tension on their dopaminergic differentiation</div> <div itemprodp="datePublished">Tue Jun 23 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24633919"> <div itemprop="name">Characterization of the 9L gliosarcoma implanted in the Fischer rat: an orthotopic model for a grade IV brain tumor.</div> </a> <div itemprop="about">Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine</div> <div itemprop="author">Bouchet A,Bidart M,Miladi I,Le Clec'h C,Serduc R,Coutton C,Regnard P,Khalil E,Dufort S,Lemasson B,Laissue J,Pelletier L,Le Duc G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study an orthotopic model of grade IV brain tumor based on Fischer rats implanted in the right caudate nucleus of the brain with the 9L gliosarcoma</div> <div itemprodp="datePublished">Tue Jul 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24851905"> <div itemprop="name">Novel epigenetic target therapy for prostate cancer: a preclinical study.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Naldi I,Taranta M,Gherardini L,Pelosi G,Viglione F,Grimaldi S,Pani L,Cinti C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to research a preclinical study on a novel epigenetic target therapy for prostate cancer</div> <div itemprodp="datePublished">Tue Jan 20 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24472151"> <div itemprop="name">Spdef deletion rescues the crypt cell proliferation defect in conditional Gata6 null mouse small intestine.</div> </a> <div itemprop="about">BMC molecular biology</div> <div itemprop="author">Aronson BE,Stapleton KA,Vissers LA,Stokhuijzen E,Bruijnzeel H,Krasinski SD</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Spdef as a downstream effector of Gata6 and its role in modulating intestinal crypt cell proliferation</div> <div itemprodp="datePublished">Tue Jan 28 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25296973"> <div itemprop="name">CAMK2N1 inhibits prostate cancer progression through androgen receptor-dependent signaling.</div> </a> <div itemprop="about">Oncotarget</div> <div itemprop="author">Wang T,Guo S,Liu Z,Wu L,Li M,Yang J,Chen R,Liu X,Xu H,Cai S,Chen H,Li W,Xu S,Wang L,Hu Z,Zhuang Q,Wang L,Wu K,Liu J,Ye Z,Ji JY,Wang C,Chen K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to investigate the anti-tumor effect of CAMK2N1 on prostate cancer progression</div> <div itemprodp="datePublished">Sat Nov 15 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25063730"> <div itemprop="name">DNA damage signaling regulates age-dependent proliferative capacity of quiescent inner ear supporting cells.</div> </a> <div itemprop="about">Aging</div> <div itemprop="author">Laos M,Anttonen T,Kirjavainen A,af Hällström T,Laiho M,Pirvola U</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study how proliferative restrictions of supporting cells are linked with DNA damage signaling</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24332836"> <div itemprop="name">Lgr5+ stem cells are indispensable for radiation-induced intestinal regeneration.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Metcalfe C,Kljavin NM,Ybarra R,de Sauvage FJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study the role of Lgr5-positive stem cells during radiation-induced intestinal regeneration</div> <div itemprodp="datePublished">Thu Feb 06 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24516524"> <div itemprop="name">Neural crest-derived mesenchymal cells require Wnt signaling for their development and drive invagination of the telencephalic midline.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Choe Y,Zarbalis KS,Pleasure SJ</div> <div itemprop="description">MA5-14520 was used in western blot to study the role of Wnt signaling in the development of neural crest-derived mesenchymal cells and in the formation of cranial mesenchymal structures</div> <div itemprodp="datePublished">Tue Jan 13 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24528896"> <div itemprop="name">Expression of a Y-located human proto-oncogene TSPY in a transgenic mouse model of prostate cancer.</div> </a> <div itemprop="about">Cell & bioscience</div> <div itemprop="author">Kido T,Schubert S,Hatakeyama S,Ohyama C,Schmidtke J,Lau YF</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to use a murine transgenic model to study the role of the Y-chromosome locatated human TSPY proto-oncogene in prostate cancer oncogenesis</div> <div itemprodp="datePublished">Mon Feb 17 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24797069"> <div itemprop="name">Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Helm O,Mennrich R,Petrick D,Goebel L,Freitag-Wolf S,Röder C,Kalthoff H,Röcken C,Sipos B,Kabelitz D,Schäfer H,Oberg HH,Wesch D,Sebens S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to characterize stroma cells and ductal epithelium comparing chronic pancreatitis and pancreatic ductal adenocarcinoma</div> <div itemprodp="datePublished">Fri Jun 12 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23455185"> <div itemprop="name">Molecular analysis of the KIT gene in gastrointestinal stromal tumors with novel mutations.</div> </a> <div itemprop="about">Applied immunohistochemistry & molecular morphology : AIMM</div> <div itemprop="author">Calibasi G,Baskin Y,Alyuruk H,Cavas L,Oztop I,Sagol O,Atila K,Ellidokuz H,Yilmaz U</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the clinicopathology of gastrointestinal stromal tumors with novel KIT mutations</div> <div itemprodp="datePublished">Wed Jan 01 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24781370"> <div itemprop="name">Conditioned medium from hypoxic bone marrow-derived mesenchymal stem cells enhances wound healing in mice.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Chen L,Xu Y,Zhao J,Zhang Z,Yang R,Xie J,Liu X,Qi S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the improved murine skin wound healing observed following treatment with conditioned medium obtained from hypoxic cultures of bone marrow-derived mesenchymal stem cells</div> <div itemprodp="datePublished">Thu Jan 22 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24520381"> <div itemprop="name">Targeted biomarker profiling of matched primary and metastatic estrogen receptor positive breast cancers.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Schleifman EB,Desai R,Spoerke JM,Xiao Y,Wong C,Abbas I,O'Brien C,Patel R,Sumiyoshi T,Fu L,Tam RN,Koeppen H,Wilson TR,Raja R,Hampton GM,Lackner MR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to analyze matched primary and metastatic tissue from ER-positive breast cancer patients for the expression of a panel of biomarkers</div> <div itemprodp="datePublished">Mon Oct 13 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25474466"> <div itemprop="name">Immune status, strain background, and anatomic site of inoculation affect mouse papillomavirus (MmuPV1) induction of exophytic papillomas or endophytic trichoblastomas.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Sundberg JP,Stearns TM,Joh J,Proctor M,Ingle A,Silva KA,Dadras SS,Jenson AB,Ghim SJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to analyze mouse papillomavirus (MmuPV1) induction of endophytic trichoblastomas and exophytic papillomas for strain background, immune status, and anatomic site of inoculation</div> <div itemprodp="datePublished">Tue Jul 28 00:00:00 EDT 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24831012"> <div itemprop="name">Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Zhang H,von Gise A,Liu Q,Hu T,Tian X,He L,Pu W,Huang X,He L,Cai CL,Camargo FD,Pu WT,Zhou B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study atrioventricular endothelial-to-mesenchymal transition and the role of Yap1</div> <div itemprodp="datePublished">Fri Jul 04 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24744701"> <div itemprop="name">Tis21 is required for adult neurogenesis in the subventricular zone and for olfactory behavior regulating cyclins, BMP4, Hes1/5 and Ids.</div> </a> <div itemprop="about">Frontiers in cellular neuroscience</div> <div itemprop="author">Farioli-Vecchioli S,Ceccarelli M,Saraulli D,Micheli L,Cannas S,D'Alessandro F,Scardigli R,Leonardi L,Cinà I,Costanzi M,Mattera A,Cestari V,Tirone F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Tis21 in adult subventricular neurogenesis and olfactory performance</div> <div itemprodp="datePublished">Fri Apr 18 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/25551829"> <div itemprop="name">Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche.</div> </a> <div itemprop="about">BMC veterinary research</div> <div itemprop="author">Schotanus BA,Kruitwagen HS,van den Ingh TS,van Wolferen ME,Rothuizen J,Penning LC,Spee B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to study canine hepatic progenitor cell niche activation by enhanced Wnt/beta-catenin and Notch signaling</div> <div itemprodp="datePublished">Wed Dec 31 00:00:00 EST 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23446420"> <div itemprop="name">GLI activation by atypical protein kinase C ι/λ regulates the growth of basal cell carcinomas.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Atwood SX,Li M,Lee A,Tang JY,Oro AE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the modulation of basal cell carcinoma growth by atypical PKC iota/lambda-mediated activation of the GLI transcription factor</div> <div itemprodp="datePublished">Thu Feb 28 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23890787"> <div itemprop="name">A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.</div> </a> <div itemprop="about">Cancer cell</div> <div itemprop="author">Pribluda A,Elyada E,Wiener Z,Hamza H,Goldstein RE,Biton M,Burstain I,Morgenstern Y,Brachya G,Billauer H,Biton S,Snir-Alkalay I,Vucic D,Schlereth K,Mernberger M,Stiewe T,Oren M,Alitalo K,Pikarsky E,Ben-Neriah Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the senescence-associated inflammatory response and how it can switch from being cancer inhibitory to a cancer promoting</div> <div itemprodp="datePublished">Mon Aug 12 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23584070"> <div itemprop="name">Intrahepatic myeloid-cell aggregates enable local proliferation of CD8(+) T cells and successful immunotherapy against chronic viral liver infection.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Huang LR,Wohlleber D,Reisinger F,Jenne CN,Cheng RL,Abdullah Z,Schildberg FA,Odenthal M,Dienes HP,van Rooijen N,Schmitt E,Garbi N,Croft M,Kurts C,Kubes P,Protzer U,Heikenwalder M,Knolle PA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the local expansion of CD8-positice T-cells in intrahepatic myeloid-cell aggregates and the implications for chronic hepatic viral infection immunotherapy</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23542688"> <div itemprop="name">Live imaging of astrocyte responses to acute injury reveals selective juxtavascular proliferation.</div> </a> <div itemprop="about">Nature neuroscience</div> <div itemprop="author">Bardehle S,Krüger M,Buggenthin F,Schwausch J,Ninkovic J,Clevers H,Snippert HJ,Theis FJ,Meyer-Luehmann M,Bechmann I,Dimou L,Götz M</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry and immunohistochemistry to use in vivo two-photon laser-scanning microscopy to study the proliferation of juxtavascular astrocytes in response to injury in the adult murine brain</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23395447"> <div itemprop="name">Human iPSC-derived oligodendrocyte progenitor cells can myelinate and rescue a mouse model of congenital hypomyelination.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Wang S,Bates J,Li X,Schanz S,Chandler-Militello D,Levine C,Maherali N,Studer L,Hochedlinger K,Windrem M,Goldman SA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the myelination and rescue of a murine model of congenital hypomyelination using oligidendrocyte precursor cells derived from human induced pluripotent stem cells</div> <div itemprodp="datePublished">Thu Feb 07 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23290136"> <div itemprop="name">Regulation of glycolysis by Pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Takubo K,Nagamatsu G,Kobayashi CI,Nakamura-Ishizu A,Kobayashi H,Ikeda E,Goda N,Rahimi Y,Johnson RS,Soga T,Hirao A,Suematsu M,Suda T</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the modulation of hematopoietic stem cell quiescence by a Pdk-regulated glycolytic cell cycle check point</div> <div itemprodp="datePublished">Thu Jan 03 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23850243"> <div itemprop="name">Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Schepers K,Pietras EM,Reynaud D,Flach J,Binnewies M,Garg T,Wagers AJ,Hsiao EC,Passegué E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the remodeling of the endosteal bone marrow niche into a self-renewing leukemic niche by myeloproliferative neoplasia</div> <div itemprodp="datePublished">Thu Sep 05 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23202733"> <div itemprop="name">Lithium rescues synaptic plasticity and memory in Down syndrome mice.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Contestabile A,Greco B,Ghezzi D,Tucci V,Benfenati F,Gasparini L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the molecular and cellular mechanisms underlying the beneficial effects of lithium on synaptic plasticity and memory in a murine model of Down syndrome</div> <div itemprodp="datePublished">Tue Jan 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23643936"> <div itemprop="name">The ventral hippocampus is the embryonic origin for adult neural stem cells in the dentate gyrus.</div> </a> <div itemprop="about">Neuron</div> <div itemprop="author">Li G,Fang L,Fernández G,Pleasure SJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the embryonic origin of long-lived adult neural stem cells of the dentate gyrus</div> <div itemprodp="datePublished">Wed May 22 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23465834"> <div itemprop="name">Enhanced liver progenitor cell survival and differentiation in vivo by spheroid implantation in a vascularized tissue engineering chamber.</div> </a> <div itemprop="about">Biomaterials</div> <div itemprop="author">Yap KK,Dingle AM,Palmer JA,Dhillon RS,Lokmic Z,Penington AJ,Yeoh GC,Morrison WA,Mitchell GM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop a novel vascularized tissue engineering chamber in combination with liver progenitor cell spheroids that results in enhanced cell survival</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24045180"> <div itemprop="name">Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Flanigan SA,Pitts TM,Newton TP,Kulikowski GN,Tan AC,McManus MC,Spreafico A,Kachaeva MI,Selby HM,Tentler JJ,Eckhardt SG,Leong S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the synergistic therapeutic effects in colorectal cancer of combined pharmacological inhibition of MEK and IGR1R/IR</div> <div itemprodp="datePublished">Fri Nov 15 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23532891"> <div itemprop="name">Serial diffusion MRI to monitor and model treatment response of the targeted nanotherapy CRLX101.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Ng TS,Wert D,Sohi H,Procissi D,Colcher D,Raubitschek AA,Jacobs RE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the use of serial diffusion MRI to monitor the response to a cyclodextrin polymer nanoparticle containing a DNA topoisomerase I inhibitor in a murine lymphoma model</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23444213"> <div itemprop="name">Targeting the NF-κB and mTOR pathways with a quinoxaline urea analog that inhibits IKKβ for pancreas cancer therapy.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Radhakrishnan P,Bryant VC,Blowers EC,Rajule RN,Gautam N,Anwar MM,Mohr AM,Grandgenett PM,Bunt SK,Arnst JL,Lele SM,Alnouti Y,Hollingsworth MA,Natarajan A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the therapeutic activity and molecular mechanism of a quinoxaline urea-based IKKbeta inhibitor in pancreatic cancer</div> <div itemprodp="datePublished">Mon Apr 15 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23423975"> <div itemprop="name">Dynamics of senescent cell formation and retention revealed by p14ARF induction in the epidermis.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Tokarsky-Amiel R,Azazmeh N,Helman A,Stein Y,Hassan A,Maly A,Ben-Porath I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of p14ARF in cellular senescence using a conditional transgenic murine model</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23811942"> <div itemprop="name">Acquired expression of NFATc1 downregulates E-cadherin and promotes cancer cell invasion.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Oikawa T,Nakamura A,Onishi N,Yamada T,Matsuo K,Saya H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of E-cadherin downregulation in the mechanism by which acquired expression of NFATc1 promotes the invasiveness of human carcinoma cells</div> <div itemprodp="datePublished">Thu Aug 15 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24154871"> <div itemprop="name">PTEN loss mitigates the response of medulloblastoma to Hedgehog pathway inhibition.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Metcalfe C,Alicke B,Crow A,Lamoureux M,Dijkgraaf GJ,Peale F,Gould SE,de Sauvage FJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the anti-tumor effects of Hedgehog pathway inhibition in medulloblastoma and the effects of PTEN loss</div> <div itemprodp="datePublished">Sun Dec 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23576558"> <div itemprop="name">FGFR1 is essential for prostate cancer progression and metastasis.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Yang F,Zhang Y,Ressler SJ,Ittmann MM,Ayala GE,Dang TD,Wang F,Rowley DR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the progression and metastasis of prostate cancer and the essential role played by FGFR1 signaling</div> <div itemprodp="datePublished">Sat Jun 15 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23752588"> <div itemprop="name">State-dependent signaling by Cav1.2 regulates hair follicle stem cell function.</div> </a> <div itemprop="about">Genes & development</div> <div itemprop="author">Yucel G,Altindag B,Gomez-Ospina N,Rana A,Panagiotakos G,Lara MF,Dolmetsch R,Oro AE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which Cav1.2 modulates the function of hair follicle stem cells</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23456631"> <div itemprop="name">Hepatic regeneration and functional recovery following partial liver resection in an experimental model of hepatic steatosis treated with omega-3 fatty acids.</div> </a> <div itemprop="about">The British journal of surgery</div> <div itemprop="author">Marsman HA,de Graaf W,Heger M,van Golen RF,Ten Kate FJ,Bennink R,van Gulik TM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the beneficial effects of omega-3 fatty acids on liver regeneration in a rat model of hepatic steatosis</div> <div itemprodp="datePublished">Mon Apr 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23603001"> <div itemprop="name">Fibrin-based scaffold incorporating VEGF- and bFGF-loaded nanoparticles stimulates wound healing in diabetic mice.</div> </a> <div itemprop="about">Acta biomaterialia</div> <div itemprop="author">Losi P,Briganti E,Errico C,Lisella A,Sanguinetti E,Chiellini F,Soldani G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the stimulation of murine diabetic wound healing by a fibrin-based scaffold incorporating nanoparticles containing VEGF and bFGF</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23630298"> <div itemprop="name">Systemic regulation of the age-related decline of pancreatic β-cell replication.</div> </a> <div itemprop="about">Diabetes</div> <div itemprop="author">Salpeter SJ,Khalaileh A,Weinberg-Corem N,Ziv O,Glaser B,Dor Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the age-related decline in the replicative capacity of panceatic beta-cells and the potential involvement of systemic factors</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22484424"> <div itemprop="name">eIF4F suppression in breast cancer affects maintenance and progression.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Nasr Z,Robert F,Porco JA,Muller WJ,Pelletier J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role and therapeutic potential of the mTOR-eIF4F axis in breast cancer</div> <div itemprodp="datePublished">Thu Feb 14 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22689059"> <div itemprop="name">Cooperation between p53 and the telomere-protecting shelterin component Pot1a in endometrial carcinogenesis.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Akbay EA,Peña CG,Ruder D,Michel JA,Nakada Y,Pathak S,Multani AS,Chang S,Castrillon DH</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the roles of p53 and Pot1a in endometrial carcinogenesis</div> <div itemprodp="datePublished">Thu Apr 25 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24168763"> <div itemprop="name">Therapeutic targeting of erbB3 with MM-121/SAR256212 enhances antitumor activity of paclitaxel against erbB2-overexpressing breast cancer.</div> </a> <div itemprop="about">Breast cancer research : BCR</div> <div itemprop="author">Wang S,Huang J,Lyu H,Cai B,Yang X,Li F,Tan J,Edgerton SM,Thor AD,Lee CK,Liu B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the enhanced anti-tumor effects in models of erbB2-expressing breast cancer of a combination of paclitaxel plus an anti-erbB3 antibody</div> <div itemprodp="datePublished">Thu Sep 11 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23558567"> <div itemprop="name">K5/K14-positive cells contribute to salivary gland-like breast tumors with myoepithelial differentiation.</div> </a> <div itemprop="about">Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc</div> <div itemprop="author">Boecker W,Stenman G,Loening T,Andersson MK,Bankfalvi A,von Holstein S,Heegaard S,Lange A,Berg T,Samoilova V,Tiemann K,Buchwalow I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study myoepithelial differentiation in salivary gland-like breast tumors and the involvement of cells expressing K5 and K14 keratins</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23839966"> <div itemprop="name">Cyclin D1 is required for proliferation of Olig2-expressing progenitor cells in the injured cerebral cortex.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Nobs L,Nestel S,Kulik A,Nitsch C,Atanasoski S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of cyclin D1 and Cdk4 in the cerebral cortical injury-induced proliferation of Olig2-positive oligodendrocyte progenitors in a murine model</div> <div itemprodp="datePublished">Sun Sep 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23910708"> <div itemprop="name">Is Ki-67 expression prognostic for local relapse in early-stage breast cancer patients treated with breast conservation therapy (BCT)?</div> </a> <div itemprop="about">International journal of radiation oncology, biology, physics</div> <div itemprop="author">Hafeez F,Neboori HJ,Harigopal M,Wu H,Haffty BG,Yang Q,Schiff D,Moran MS</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study whether Ki67 expression is of prognostic value in breast cancer patients undergoing breast conservation therapy</div> <div itemprodp="datePublished">Tue Oct 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23347294"> <div itemprop="name">Histology-driven data mining of lipid signatures from multiple imaging mass spectrometry analyses: application to human colorectal cancer liver metastasis biopsies.</div> </a> <div itemprop="about">Analytical chemistry</div> <div itemprop="author">Thomas A,Patterson NH,Marcinkiewicz MM,Lazaris A,Metrakos P,Chaurand P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the use of imaging mass spectrometry data mining to identify lipid signatures of relevance to human colorectal cancer liver metastasis</div> <div itemprodp="datePublished">Tue Mar 05 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22931929"> <div itemprop="name">Dual role of apoptosis-associated speck-like protein containing a CARD (ASC) in tumorigenesis of human melanoma.</div> </a> <div itemprop="about">The Journal of investigative dermatology</div> <div itemprop="author">Liu W,Luo Y,Dunn JH,Norris DA,Dinarello CA,Fujita M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms underlying the role of ASC in human melanoma tumorigenesis</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23096717"> <div itemprop="name">An in vivo screen of secreted proteins identifies adiponectin as a regulator of murine cutaneous wound healing.</div> </a> <div itemprop="about">The Journal of investigative dermatology</div> <div itemprop="author">Salathia NS,Shi J,Zhang J,Glynne RJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of adiponectin to promote cutaneous wound healing in mice</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23240585"> <div itemprop="name">Superoxide dismutase mimetic, MnTE-2-PyP, attenuates chronic hypoxia-induced pulmonary hypertension, pulmonary vascular remodeling, and activation of the NALP3 inflammasome.</div> </a> <div itemprop="about">Antioxidants & redox signaling</div> <div itemprop="author">Villegas LR,Kluck D,Field C,Oberley-Deegan RE,Woods C,Yeager ME,El Kasmi KC,Savani RC,Bowler RP,Nozik-Grayck E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the protective effects of a pharmacological SOD mimetic against the effects of chronic hypoxia on pulmonary hypertension, vascular changes and inflammatory responses</div> <div itemprodp="datePublished">Fri May 10 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23354807"> <div itemprop="name">Combination therapy of cilengitide with belotecan against experimental glioblastoma.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Kim YH,Lee JK,Kim B,DeWitt JP,Lee JE,Han JH,Kim SK,Oh CW,Kim CY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the efficacy of combination therapy with cilengitide plus belotecan against murine xenografts of human glioblastoma</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23959140"> <div itemprop="name">Targeting 5-HT(1A) receptors in astrocytes to protect dopaminergic neurons in Parkinsonian models.</div> </a> <div itemprop="about">Neurobiology of disease</div> <div itemprop="author">Miyazaki I,Asanuma M,Murakami S,Takeshima M,Torigoe N,Kitamura Y,Miyoshi K</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the protection of dopaminergic neurons in models of Parkinson's disease by agonist-mediated activation of astrocyte 5-HT(1A) receptors and the role of increased metallothionein expression</div> <div itemprodp="datePublished">Fri Nov 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23554478"> <div itemprop="name">Proliferation and cell cycle dynamics in the developing stellate ganglion.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Gonsalvez DG,Cane KN,Landman KA,Enomoto H,Young HM,Anderson CR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study cellular proliferation in the murine embryonic stellate ganglion</div> <div itemprodp="datePublished">Wed Apr 03 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23093699"> <div itemprop="name">MEN1 intragenic deletions may represent the most prevalent somatic event in sporadic primary hyperparathyroidism.</div> </a> <div itemprop="about">European journal of endocrinology</div> <div itemprop="author">Alvelos MI,Vinagre J,Fonseca E,Barbosa E,Teixeira-Gomes J,Sobrinho-Simões M,Soares P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of intragenic deletions of MEN1 in sporadic primary hyperparathyroidism</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23254778"> <div itemprop="name">Characterization of WWOX inactivation in murine mammary gland development.</div> </a> <div itemprop="about">Journal of cellular physiology</div> <div itemprop="author">Abdeen SK,Salah Z,Khawaled S,Aqeilan RI</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of WWOX in normal breast development and tumorigenesis in a conditional knockout mouse model</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23705946"> <div itemprop="name">In vitro and in vivo activity of cabozantinib (XL184), an inhibitor of RET, MET, and VEGFR2, in a model of medullary thyroid cancer.</div> </a> <div itemprop="about">Thyroid : official journal of the American Thyroid Association</div> <div itemprop="author">Bentzien F,Zuzow M,Heald N,Gibson A,Shi Y,Goon L,Yu P,Engst S,Zhang W,Huang D,Zhao L,Vysotskaia V,Chu F,Bautista R,Cancilla B,Lamb P,Joly AH,Yakes FM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the biochemical activity of cabozantiinib against disease-associated RET mutants and its growth inhibitory activity in medullary thyroid cancer models</div> <div itemprodp="datePublished">Sun Dec 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23188710"> <div itemprop="name">Gpr177, a novel locus for bone mineral density and osteoporosis, regulates osteogenesis and chondrogenesis in skeletal development.</div> </a> <div itemprop="about">Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research</div> <div itemprop="author">Maruyama T,Jiang M,Hsu W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the molecular mechanisms underlying the modulation of skeletal development by Gpr177</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23887155"> <div itemprop="name">Fibrosarcoma-like lipomatous neoplasm: a reappraisal of so-called spindle cell liposarcoma defining a unique lipomatous tumor unrelated to other liposarcomas.</div> </a> <div itemprop="about">The American journal of surgical pathology</div> <div itemprop="author">Deyrup AT,Chibon F,Guillou L,Lagarde P,Coindre JM,Weiss SW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a distinct group of liposarcomas termed fibrosarcoma-like lipomatous neoplasm</div> <div itemprodp="datePublished">Sun Sep 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23689832"> <div itemprop="name">Combined targeting of mTOR and AKT is an effective strategy for basal-like breast cancer in patient-derived xenograft models.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Xu S,Li S,Guo Z,Luo J,Ellis MJ,Ma CX</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to use patient-derived xenograft models to study the efficacy of combined inhibition of mTOR and Akt in basal-like breast cancer</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23499550"> <div itemprop="name">miR-92a inhibits peritoneal dissemination of ovarian cancer cells by inhibiting integrin α5 expression.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Ohyagi-Hara C,Sawada K,Kamiura S,Tomita Y,Isobe A,Hashimoto K,Kinose Y,Mabuchi S,Hisamatsu T,Takahashi T,Kumasawa K,Nagata S,Morishige K,Lengyel E,Kurachi H,Kimura T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of reduced integrin ?5 expression in the mechanism by which miR-92a inhibits the peritoneal dissemination of ovarian cancer cells</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24012678"> <div itemprop="name">The regulation of SOX7 and its tumor suppressive role in breast cancer.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Stovall DB,Wan M,Miller LD,Cao P,Maglic D,Zhang Q,Stampfer MR,Liu W,Xu J,Sui G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the regulation of the SOX7 tumor suppressor in breast cancer</div> <div itemprodp="datePublished">Fri Nov 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23938323"> <div itemprop="name">Cooperation between Dmp1 loss and cyclin D1 overexpression in breast cancer.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Zhu S,Mott RT,Fry EA,Taneja P,Kulik G,Sui G,Inoue K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the significance in breast cancer of Dmp1 loss coupled with cyclin D1 overexpression</div> <div itemprodp="datePublished">Tue Oct 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23690116"> <div itemprop="name">Expression of Lewis X is associated with poor prognosis in triple-negative breast cancer.</div> </a> <div itemprop="about">American journal of clinical pathology</div> <div itemprop="author">Koh YW,Lee HJ,Ahn JH,Lee JW,Gong G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the prognostic value of Lewis X expression in triple-negative breast cancer</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22610535"> <div itemprop="name">The oxysterol receptors LXRα and LXRβ suppress proliferation in the colon.</div> </a> <div itemprop="about">Molecular carcinogenesis</div> <div itemprop="author">Vedin LL,Gustafsson JÅ,Steffensen KR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of oxysterol receptors LXRalpha and LXRbeta in suppressing proliferation in the colon</div> <div itemprodp="datePublished">Fri Nov 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23769395"> <div itemprop="name">Impact of N-tau on adult hippocampal neurogenesis, anxiety, and memory.</div> </a> <div itemprop="about">Neurobiology of aging</div> <div itemprop="author">Pristerà A,Saraulli D,Farioli-Vecchioli S,Strimpakos G,Costanzi M,di Certo MG,Cannas S,Ciotti MT,Tirone F,Mattei E,Cestari V,Canu N</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry and immunohistochemistry to study the effects of a pathogenic tau fragment on hippocampal neurogenesis, behaviour and learning</div> <div itemprodp="datePublished">Fri Nov 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23748362"> <div itemprop="name">Diet-induced obesity increases tumor growth and promotes anaplastic change in thyroid cancer in a mouse model.</div> </a> <div itemprop="about">Endocrinology</div> <div itemprop="author">Kim WG,Park JW,Willingham MC,Cheng SY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the molecular mechanisms underlying the promotion of anaplastic change and tumor growth in a murine model of thyroid cancer by a high-fat diet</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23555235"> <div itemprop="name">An integrated computational/experimental model of lymphoma growth.</div> </a> <div itemprop="about">PLoS computational biology</div> <div itemprop="author">Frieboes HB,Smith BR,Chuang YL,Ito K,Roettgers AM,Gambhir SS,Cristini V</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop an in silico model of the growth of non-Hodgkin's lymphoma</div> <div itemprodp="datePublished">Fri Nov 08 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23471881"> <div itemprop="name">Hepatitis B virus X protein upregulates oncogene Rab18 to result in the dysregulation of lipogenesis and proliferation of hepatoma cells.</div> </a> <div itemprop="about">Carcinogenesis</div> <div itemprop="author">You X,Liu F,Zhang T,Li Y,Ye L,Zhang X</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the abnormal lipogenesis and induction of hepatoma cell proliferation by HBV X-protein and the role of the Rab18 oncogene</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23749771"> <div itemprop="name">Nuclear karyopherin-α2 expression in primary lesions and metastatic lymph nodes was associated with poor prognosis and progression in gastric cancer.</div> </a> <div itemprop="about">Carcinogenesis</div> <div itemprop="author">Altan B,Yokobori T,Mochiki E,Ohno T,Ogata K,Ogawa A,Yanai M,Kobayashi T,Luvsandagva B,Asao T,Kuwano H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the prognostic and predictive value of the immunohistochemical expression of KPNA2 in primary lesions and metastatic lymph nodes of patients with gastric cancer</div> <div itemprodp="datePublished">Tue Oct 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23531216"> <div itemprop="name">MEK inhibition increases lapatinib sensitivity via modulation of FOXM1.</div> </a> <div itemprop="about">Current medicinal chemistry</div> <div itemprop="author">Gayle SS,Castellino RC,Buss MC,Nahta R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of FOXM1 in the mechanism by which MEK inhibition increases sensitivity to lapatinib</div> <div itemprodp="datePublished">Fri Nov 08 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23384443"> <div itemprop="name">Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.</div> </a> <div itemprop="about">Molecular and cellular neurosciences</div> <div itemprop="author">Ransome MI,Hannan AJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the significance of reduced Akt levels in the decreased levels of basal and running-induced neurogenesis observed in the hippocampus of a murine model of Huntington's disease</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23358691"> <div itemprop="name">Is survivin expression prognostic or predictive in malignant pleural mesothelioma?</div> </a> <div itemprop="about">Virchows Archiv : an international journal of pathology</div> <div itemprop="author">Hmeljak J,Erčulj N,Dolžan V,Pižem J,Kern I,Kovač V,Cemažar M,Cör A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the prognostic and predictive value of survivin expression in malignant pleural mesothelioma</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22840462"> <div itemprop="name">Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer.</div> </a> <div itemprop="about">Breast (Edinburgh, Scotland)</div> <div itemprop="author">Krüger K,Stefansson IM,Collett K,Arnes JB,Aas T,Akslen LA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the association of endothelial nestin and Ki-67 coexpression with microvessel proliferation and aggressive breast cancer</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23467742"> <div itemprop="name">Testosterone levels influence mouse fetal Leydig cell progenitors through notch signaling.</div> </a> <div itemprop="about">Biology of reproduction</div> <div itemprop="author">Defalco T,Saraswathula A,Briot A,Iruela-Arispe ML,Capel B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to show the mechanism for the effect of testosterone on mouse fetal Leydig cell progenitors</div> <div itemprodp="datePublished">Mon Apr 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23043896"> <div itemprop="name">Enhanced oxygen supply improves islet viability in a new bioartificial pancreas.</div> </a> <div itemprop="about">Cell transplantation</div> <div itemprop="author">Barkai U,Weir GC,Colton CK,Ludwig B,Bornstein SR,Brendel MD,Neufeld T,Bremer C,Leon A,Evron Y,Yavriyants K,Azarov D,Zimermann B,Maimon S,Shabtay N,Balyura M,Rozenshtein T,Vardi P,Bloch K,de Vos P,Rotem A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the function of an implantable bioartificial pancreas and the requirement for an enhanced supply of oxygen</div> <div itemprodp="datePublished">Tue Apr 08 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23673452"> <div itemprop="name">SIRT1 suppresses breast cancer growth through downregulation of the Bcl-2 protein.</div> </a> <div itemprop="about">Oncology reports</div> <div itemprop="author">Kuo SJ,Lin HY,Chien SY,Chen DR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of reduced Bcl-2 levels in the mechanism by which SIRT1 inhibition suppresses the growth of breast cancer</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22794784"> <div itemprop="name">Methyl donor deficiency affects small-intestinal differentiation and barrier function in rats.</div> </a> <div itemprop="about">The British journal of nutrition</div> <div itemprop="author">Bressenot A,Pooya S,Bossenmeyer-Pourie C,Gauchotte G,Germain A,Chevaux JB,Coste F,Vignaud JM,Guéant JL,Peyrin-Biroulet L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects on rat small-intestinal enterocyte differentiation and barrier function of a diet deficient in methyl donors</div> <div itemprodp="datePublished">Thu Feb 28 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23486009"> <div itemprop="name">Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS.</div> </a> <div itemprop="about">American journal of physiology. Renal physiology</div> <div itemprop="author">Zhang J,Pippin JW,Krofft RD,Naito S,Liu ZH,Shankland SJ</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the effect of glucocorticoid therapy on the repopulation of podocytes by renal progenitor cells in a murine model of focal segmental glomerulosclerosis</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22429721"> <div itemprop="name">Donor cornea transfer from Optisol GS to organ culture storage: a two-step procedure to increase donor tissue lifespan.</div> </a> <div itemprop="about">Acta ophthalmologica</div> <div itemprop="author">Haug K,Azqueta A,Johnsen-Soriano S,Shahdadfar A,Drolsum LK,Moe MC,Røger MT,Romero FJ,Collins AR,Nicolaissen B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of transfer from Optisol-GS to organ culture storage of the lifespan of donor corneas</div> <div itemprodp="datePublished">Wed May 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23222909"> <div itemprop="name">VEGF expression and microvascular responses to severe transient hypoxia in the fetal sheep brain.</div> </a> <div itemprop="about">Pediatric research</div> <div itemprop="author">Baburamani AA,Castillo-Melendez M,Walker DW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of severe transient cerebral hypoxia on VEGF expression and microvascular changes in a fetal sheep model</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23275061"> <div itemprop="name">LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models.</div> </a> <div itemprop="about">Investigational new drugs</div> <div itemprop="author">Yan SB,Peek VL,Ajamie R,Buchanan SG,Graff JR,Heidler SA,Hui YH,Huss KL,Konicek BW,Manro JR,Shih C,Stewart JA,Stewart TR,Stout SL,Uhlik MT,Um SL,Wang Y,Wu W,Yan L,Yang WJ,Zhong B,Walgren RA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the anti-tumor activity in murine xenograft models of a novel bioavailable kinase inhibitor displaying activity against multiple receptor tyrosine kinases</div> <div itemprodp="datePublished">Thu Aug 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23266444"> <div itemprop="name">Signature patterns of human papillomavirus type 16 in invasive anal carcinoma.</div> </a> <div itemprop="about">Human pathology</div> <div itemprop="author">Valmary-Degano S,Jacquin E,Prétet JL,Monnien F,Girardo B,Arbez-Gindre F,Joly M,Bosset JF,Kantelip B,Mougin C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study HPV16 infection in patients with invasive anal carcinoma</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23971516"> <div itemprop="name">Lack of high-dose radiation mediated prostate cancer promotion and low-dose radiation adaptive response in the TRAMP mouse model.</div> </a> <div itemprop="about">Radiation research</div> <div itemprop="author">Lawrence MD,Ormsby RJ,Blyth BJ,Bezak E,England G,Newman MR,Tilley WD,Sykes PJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the lack of effect of either low-dose or high-dose radiation on prostate cancer growth in the TRAMP mouse model</div> <div itemprodp="datePublished">Tue Oct 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23722018"> <div itemprop="name">Contribution of DOG1 expression to the diagnosis of gastrointestinal stromal tumors.</div> </a> <div itemprop="about">Pathology, research and practice</div> <div itemprop="author">Kara T,Serinsoz E,Arpaci RB,Gubur O,Orekici G,Ata A,Colak T,Arican A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the diagnostic value of the immunohistochemical expression of DOG1 in gastrointestinal stromal tumors</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23358645"> <div itemprop="name">The PPARγ agonist pioglitazone crosses the blood-brain barrier and reduces tumor growth in a human xenograft model.</div> </a> <div itemprop="about">Cancer chemotherapy and pharmacology</div> <div itemprop="author">Grommes C,Karlo JC,Caprariello A,Blankenship D,Dechant A,Landreth GE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of pioglitazone to penetrate the murine blood-brain barrier and inhibit the growth of human glioma xenografts</div> <div itemprodp="datePublished">Mon Apr 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23727388"> <div itemprop="name">Suppression of cytochrome P450 reductase expression promotes astrocytosis in subventricular zone of adult mice.</div> </a> <div itemprop="about">Neuroscience letters</div> <div itemprop="author">Yao Y,Liu S,Wang Y,Yuan W,Ding X,Cheng T,Shen Q,Gu J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of NADPH cytochrome P450 in preventing subventricular zone astrocytosis in adult mice</div> <div itemprodp="datePublished">Mon Aug 26 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22791629"> <div itemprop="name">A cell population that strongly expresses the CB1 cannabinoid receptor in the ependyma of the rat spinal cord.</div> </a> <div itemprop="about">The Journal of comparative neurology</div> <div itemprop="author">Garcia-Ovejero D,Arevalo-Martin A,Paniagua-Torija B,Sierra-Palomares Y,Molina-Holgado E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the expression of CB1 cannabinoid receptor in the ependyma of the rat spinal cord</div> <div itemprodp="datePublished">Tue Jan 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23483698"> <div itemprop="name">Transcription factor Sox11 is essential for both embryonic and adult neurogenesis.</div> </a> <div itemprop="about">Developmental dynamics : an official publication of the American Association of Anatomists</div> <div itemprop="author">Wang Y,Lin L,Lai H,Parada LF,Lei L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the neurogenic role of Sox11 in both embryonic and adult mice</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23619346"> <div itemprop="name">The effects of ulipristal on Bax/Bcl-2, cytochrome c, Ki-67 and cyclooxygenase-2 expression in a rat model with surgically induced endometriosis.</div> </a> <div itemprop="about">European journal of obstetrics, gynecology, and reproductive biology</div> <div itemprop="author">Huniadi CA,Pop OL,Antal TA,Stamatian F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to use a rat model of endometriosis to study the effects of ulipristal on endometrial histology and the expression of Bax/Bcl-2, cytochrome c, Ki-67 and COX-2</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23881165"> <div itemprop="name">Complementary expression and repulsive signaling suggest that EphB2 and ephrin-B1 are possibly involved in epithelial boundary formation at the squamocolumnar junction in the rodent stomach.</div> </a> <div itemprop="about">Histochemistry and cell biology</div> <div itemprop="author">Ogawa K,Saeki N,Igura Y,Hayashi Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the potential involvement of EphB2 and ephrin-B1 in the formation of the epithelial boundary at the squamocolumnar junction</div> <div itemprodp="datePublished">Sun Dec 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24035263"> <div itemprop="name">FDG PET in the evaluation of phaeochromocytoma: a correlative study with MIBG scintigraphy and Ki-67 proliferative index.</div> </a> <div itemprop="about">Clinical imaging</div> <div itemprop="author">Lin M,Wong V,Yap J,Jin R,Leong P,Campbell P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study whether flurodeoxyglucose PET, MIBG scintigraphy and Ki-67 proliferation index correlate in patients with phaeochromocytoma</div> <div itemprodp="datePublished">Wed Aug 06 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24020697"> <div itemprop="name">Slow turning lateral vessel bioreactor improves embryoid body formation and cardiogenic differentiation of mouse embryonic stem cells.</div> </a> <div itemprop="about">Cellular reprogramming</div> <div itemprop="author">Rungarunlert S,Klincumhom N,Tharasanit T,Techakumphu M,Pirity MK,Dinnyes A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the increased formation of embroid bodies and cardiomyocytic differentiation of murine embryonic stem cells cultured in a slow turning lateral vessel bioreactor</div> <div itemprodp="datePublished">Tue Oct 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24289080"> <div itemprop="name">Local insulin application on the carotid artery inhibits neointima formation.</div> </a> <div itemprop="about">Canadian journal of physiology and pharmacology</div> <div itemprop="author">Chiang S,Breen DM,Guo J,Mori Y,Giacca A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the inhibition of neointima formation by local insulin administration to the carotid artery following balloon-mediated injury</div> <div itemprodp="datePublished">Sun Dec 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23401468"> <div itemprop="name">Adenovirus-mediated interferon-γ gene therapy induced human pancreatic carcinoma Capan-2 cell apoptosis in vitro and in vivo.</div> </a> <div itemprop="about">Anatomical record (Hoboken, N.J. : 2007)</div> <div itemprop="author">Xie FJ,Zhao P,Zhang YP,Liu FY,Nie XL,Zhu YH,Yu XM,Zheng QQ,Mao WM,Lu HY,Wei H,Huang W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of adenoviral delivery of IFN-gamma to inhibit the growth of a human pancreatic carcinoma cell line via the induction of apoptosis</div> <div itemprodp="datePublished">Mon Apr 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23331470"> <div itemprop="name">Role of Langerhans cells, Ki-67 protein and apoptosis in acquired cholesteatoma: prospective clinical study.</div> </a> <div itemprop="about">The Journal of laryngology and otology</div> <div itemprop="author">Akdogan V,Yilmaz I,Canpolat T,Ozluoglu LN</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Langerhans cells in the pathogenesis of acquired cholesteatoma</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22722466"> <div itemprop="name">Expression of matrix metalloproteinase-13 and Ki-67 in nonmelanoma skin cancer in xeroderma pigmentosum and non-xeroderma pigmentosum.</div> </a> <div itemprop="about">The American Journal of dermatopathology</div> <div itemprop="author">El-Hawary AK,Yassin E,Khater A,Abdelgaber S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the pathological significance of MMP13 and Ki-67 expression in basal cell carcinomas and squamous cell carcinomas in xeroderma pigmentosum patients</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24399015"> <div itemprop="name">Insulinoma diagnosed as drug-refractory epilepsy in an adolescent boy: a case report.</div> </a> <div itemprop="about">Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie</div> <div itemprop="author">Horváth E,Gozar H,Chira L,Dunca I,Kiss E,Pávai Z</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of pediatric insulinoma</div> <div itemprodp="datePublished">Wed Jul 02 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23555306"> <div itemprop="name">Differential evolutionary fate of an ancestral primate endogenous retrovirus envelope gene, the EnvV syncytin, captured for a function in placentation.</div> </a> <div itemprop="about">PLoS genetics</div> <div itemprop="author">Esnault C,Cornelis G,Heidmann O,Heidmann T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the evolutionary fates of the envV gene captured from the endogenous retrovirus type V provirus to play a role in placentation in ancestral primates</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24260314"> <div itemprop="name">Radmis, a novel mitotic spindle protein that functions in cell division of neural progenitors.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Yumoto T,Nakadate K,Nakamura Y,Sugitani Y,Sugitani-Yoshida R,Ueda S,Sakakibara S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the novel mitotic spindle protein radmis in neural progenitor cell division</div> <div itemprodp="datePublished">Mon Jul 07 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24090101"> <div itemprop="name">Phenotyping dividing cells in mouse models of neurodegenerative basal ganglia diseases.</div> </a> <div itemprop="about">BMC neuroscience</div> <div itemprop="author">Smardencas A,Rizkalla K,Kim HA,Massalas J,O'Leary C,Ehrlich ME,Schütz G,Lawrence AJ,Drago J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study murine models in order to identify the cell-types being generated from dividing progenitors in neurodegenerative basal ganglia diseases</div> <div itemprodp="datePublished">Thu Oct 03 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23618385"> <div itemprop="name">Effects of steroid hormones on differentiated glandular epithelial and stromal cells in a three dimensional cell culture model of the canine endometrium.</div> </a> <div itemprop="about">BMC veterinary research</div> <div itemprop="author">Bartel C,Tichy A,Schoenkypl S,Aurich C,Walter I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of steroid hormones on estrogen and progesterone receptor expression and cell proliferation in a 3-dimensional cell culture model of dog endometrium</div> <div itemprodp="datePublished">Wed Apr 24 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23457494"> <div itemprop="name">Glycyrrhizic acid suppresses the development of precancerous lesions via regulating the hyperproliferation, inflammation, angiogenesis and apoptosis in the colon of Wistar rats.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Khan R,Khan AQ,Lateef A,Rehman MU,Tahir M,Ali F,Hamiza OO,Sultana S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to the study the mechanisms by which glycyrrhizic acid suppresses the formation of precancerous lesions in the rat colon</div> <div itemprodp="datePublished">Mon Aug 26 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24845429"> <div itemprop="name">Specimen quality evaluation in Canadian biobanks participating in the COEUR repository.</div> </a> <div itemprop="about">Biopreservation and biobanking</div> <div itemprop="author">Le Page C,Köbel M,de Ladurantaye M,Rahimi K,Madore J,Babinszky S,Bachvarov DR,Bachvarova M,Beauchamp MC,Cass CE,Chadwick D,Colleen C,Damaraju S,Dufour J,Gotlieb WH,Kalloger SE,Portelance L,McAlpine JN,Matte I,Piché A,Shaw P,Roehrl MH,Vanderhyden BC,Watson PH,Huntsman DG,Provencher DM,Mes-Masson AM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the quality of biological samples held in Canadian biobanks forming part of the COEUR repository</div> <div itemprodp="datePublished">Mon Apr 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23593103"> <div itemprop="name">Multiple delivery of siRNA against endoglin into murine mammary adenocarcinoma prevents angiogenesis and delays tumor growth.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Dolinsek T,Markelc B,Sersa G,Coer A,Stimac M,Lavrencak J,Brozic A,Kranjc S,Cemazar M</div> <div itemprop="description">MA5-14520 was used in Immunohistochemistry to demonstrate that silencing of endoglin is a promising antiangiogenic therapy of tumors that could not be used as single treatment, but as an adjunct to the established cytotoxic treatment approaches.</div> <div itemprodp="datePublished">Fri Aug 16 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23802089"> <div itemprop="name">The microenvironment of human neuroblastoma supports the activation of tumor-associated T lymphocytes.</div> </a> <div itemprop="about">Oncoimmunology</div> <div itemprop="author">Carlson LM,De Geer A,Sveinbjørnsson B,Orrego A,Martinsson T,Kogner P,Levitskaya J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of the human neuroblastoma microenvironment to support tumor-associated T-cell activation</div> <div itemprodp="datePublished">Fri Mar 01 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24348390"> <div itemprop="name">A husband and a wife with simultaneous presentation of glioblastoma multiforme: a case report.</div> </a> <div itemprop="about">Case reports in oncology</div> <div itemprop="author">Roviello G,Petrioli R,Cerase A,Marsili S,Miracco C,Rubino G,Tini P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of husband and wife presenting simultaneously with glioblastoma multiforme</div> <div itemprodp="datePublished">Wed Dec 18 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24301314"> <div itemprop="name">APC/C-Cdh1 coordinates neurogenesis and cortical size during development.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Delgado-Esteban M,García-Higuera I,Maestre C,Moreno S,Almeida A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the modulation of cortical neurogenesis and size by APC/C-Cdh1</div> <div itemprodp="datePublished">Tue Oct 07 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23755201"> <div itemprop="name">Tumor necrosis factor-α promotes cholestasis-induced liver fibrosis in the mouse through tissue inhibitor of metalloproteinase-1 production in hepatic stellate cells.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Osawa Y,Hoshi M,Yasuda I,Saibara T,Moriwaki H,Kozawa O</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of TIMP1 production by hepatic stellate cells in the mechanism by which TNF-alpha promotes liver fibrosis in a murine model of cholestasis</div> <div itemprodp="datePublished">Tue Jan 13 00:00:00 EST 2015</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23803085"> <div itemprop="name">Suppression of β-catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA).</div> </a> <div itemprop="about">Asian Pacific journal of cancer prevention : APJCP</div> <div itemprop="author">Saad N,Esa NM,Ithnin H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of phytic acid from rice bran to reduce the expression of beta-catenin and COX-2 and to inhibit colon cancer proliferation in a rat carcinogen-induced model</div> <div itemprodp="datePublished">Tue Oct 14 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23814493"> <div itemprop="name">Inhibition of tumor angiogenesis and tumor growth by the DSL domain of human Delta-like 1 targeted to vascular endothelial cells.</div> </a> <div itemprop="about">Neoplasia (New York, N.Y.)</div> <div itemprop="author">Zhao XC,Dou GR,Wang L,Liang L,Tian DM,Cao XL,Qin HY,Wang CM,Zhang P,Han H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of a vascular endothelial cell-targeted construct containing the DSl domain of Delta-like 1 to inhibit the angiogenesis and growth of tumor cells</div> <div itemprodp="datePublished">Mon Jul 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24252742"> <div itemprop="name">Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.</div> </a> <div itemprop="about">Acta neuropathologica communications</div> <div itemprop="author">Navis AC,Niclou SP,Fack F,Stieber D,van Lith S,Verrijp K,Wright A,Stauber J,Tops B,Otte-Holler I,Wevers RA,van Rooij A,Pusch S,von Deimling A,Tigchelaar W,van Noorden CJ,Wesseling P,Leenders WP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to characterize E478 xenografts at the genetic, histologic, and metabolic level</div> <div itemprodp="datePublished">Wed May 29 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23457599"> <div itemprop="name">Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Maruyama EO,Yu HM,Jiang M,Fu J,Hsu W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Gpr177 in mammary organogenesis and Wnt-driven tumorigenesis</div> <div itemprodp="datePublished">Wed Aug 28 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23530816"> <div itemprop="name">Chemoprevention utility of silibinin and Cdk4 pathway inhibition in Apc(-/+) mice.</div> </a> <div itemprop="about">BMC cancer</div> <div itemprop="author">Karim BO,Rhee KJ,Liu G,Zheng D,Huso DL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the potential of silibin and Cdk4 inhibition for the chemoprevention of colorectal cancer</div> <div itemprodp="datePublished">Wed Mar 27 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23804451"> <div itemprop="name">Role of fibrinogen in acute ischemic kidney injury.</div> </a> <div itemprop="about">American journal of physiology. Renal physiology</div> <div itemprop="author">Sörensen-Zender I,Rong S,Susnik N,Lange J,Gueler F,Degen JL,Melk A,Haller H,Schmitt R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study renal ischemia-reperfusion injury and the roles of fibrinogen</div> <div itemprodp="datePublished">Sun Sep 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23484006"> <div itemprop="name">Effects of dual targeting of tumor cells and stroma in human glioblastoma xenografts with a tyrosine kinase inhibitor against c-MET and VEGFR2.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Navis AC,Bourgonje A,Wesseling P,Wright A,Hendriks W,Verrijp K,van der Laak JA,Heerschap A,Leenders WP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the therapeutic efficacy of a tyrosine kinase inhibitor active against both c-MET and VEGFR2 in a xenoraft model of human glioblastoma</div> <div itemprodp="datePublished">Tue Sep 03 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23472160"> <div itemprop="name">CoupTFI interacts with retinoic acid signaling during cortical development.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Harrison-Uy SJ,Siegenthaler JA,Faedo A,Rubenstein JL,Pleasure SJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the modulation of cortical development by interactions between CoupTF I and retinoic acid signaling pathways</div> <div itemprodp="datePublished">Tue Dec 03 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23520544"> <div itemprop="name">Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">El-Zaatari M,Kao JY,Tessier A,Bai L,Hayes MM,Fontaine C,Eaton KA,Merchant JL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to determine the contribution of Hedgehog signaling to gastric transformation</div> <div itemprodp="datePublished">Tue Sep 10 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23550152"> <div itemprop="name">Chemoprevention of lung squamous cell carcinoma by ginseng.</div> </a> <div itemprop="about">Cancer prevention research (Philadelphia, Pa.)</div> <div itemprop="author">Pan J,Zhang Q,Li K,Liu Q,Wang Y,You M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the chemopreventative activity of ginseng in a murine model of squamous cell carcinoma of the lung</div> <div itemprodp="datePublished">Sat Jun 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24215614"> <div itemprop="name">The anti-erbB3 antibody MM-121/SAR256212 in combination with trastuzumab exerts potent antitumor activity against trastuzumab-resistant breast cancer cells.</div> </a> <div itemprop="about">Molecular cancer</div> <div itemprop="author">Huang J,Wang S,Lyu H,Cai B,Yang X,Wang J,Liu B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the potent anti-cancer activity against erbB2-positive trastuzumab-resistant breast cancer of a combination of trastuzumab plus an anti-erbB3 antibody</div> <div itemprodp="datePublished">Mon Nov 11 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24058630"> <div itemprop="name">Simultaneous activation of Kras and inactivation of p53 induces soft tissue sarcoma and bladder urothelial hyperplasia.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Yang X,La Rosa FG,Genova EE,Huber K,Schaack J,Degregori J,Serkova NJ,Li Y,Su LJ,Kessler E,Flaig TW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the formation of soft tissue sarcoma and bladder urothelial hyperplasia following simultaneous Kras activation/p53 inactivation in a murine model</div> <div itemprodp="datePublished">Mon Jun 16 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23718816"> <div itemprop="name">A novel model of adenine-induced tubulointerstitial nephropathy in mice.</div> </a> <div itemprop="about">BMC nephrology</div> <div itemprop="author">Jia T,Olauson H,Lindberg K,Amin R,Edvardsson K,Lindholm B,Andersson G,Wernerson A,Sabbagh Y,Schiavi S,Larsson TE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to describe a novel adenine-based model of murine renal failure</div> <div itemprodp="datePublished">Thu May 30 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23800275"> <div itemprop="name">Low expression of the X-linked ribosomal protein S4 in human serous epithelial ovarian cancer is associated with a poor prognosis.</div> </a> <div itemprop="about">BMC cancer</div> <div itemprop="author">Tsofack SP,Meunier L,Sanchez L,Madore J,Provencher D,Mes-Masson AM,Lebel M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the prognostic value of the immunohistochemical expresson of RPS4X in patients with serous epithelial ovarian cancer</div> <div itemprodp="datePublished">Sat Jun 22 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23382704"> <div itemprop="name">Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.</div> </a> <div itemprop="about">PLoS genetics</div> <div itemprop="author">Schaffer AE,Taylor BL,Benthuysen JR,Liu J,Thorel F,Yuan W,Jiao Y,Kaestner KH,Herrera PL,Magnuson MA,May CL,Sander M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the central role of the Nkx6.1 transcription factor in the specification and maintenance of pancreatic beta-cells</div> <div itemprodp="datePublished">Thu May 30 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24340075"> <div itemprop="name">Label retention identifies a multipotent mesenchymal stem cell-like population in the postnatal thymus.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Osada M,Singh VJ,Wu K,Sant'Angelo DB,Pezzano M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study a postnatal thymus population of multipotent mesenchymal stem-like cells</div> <div itemprodp="datePublished">Tue Sep 30 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23463003"> <div itemprop="name">Aldara activates TLR7-independent immune defence.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Walter A,Schäfer M,Cecconi V,Matter C,Urosevic-Maiwald M,Belloni B,Schönewolf N,Dummer R,Bloch W,Werner S,Beer HD,Knuth A,van den Broek M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of Aldara to induce inflammatory immune responses independently of TLR7 activation</div> <div itemprodp="datePublished">Thu Jun 20 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23885093"> <div itemprop="name">Uterine deletion of Gp130 or Stat3 shows implantation failure with increased estrogenic responses.</div> </a> <div itemprop="about">Molecular endocrinology (Baltimore, Md.)</div> <div itemprop="author">Sun X,Bartos A,Whitsett JA,Dey SK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - frozen section to elucidate the role of Gp130 and STAT3 in the uterus during implantation</div> <div itemprodp="datePublished">Sun Sep 01 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23468915"> <div itemprop="name">Tumor stress-induced phosphoprotein1 (STIP1) as a prognostic biomarker in ovarian cancer.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Chao A,Lai CH,Tsai CL,Hsueh S,Hsueh C,Lin CY,Chou HH,Lin YJ,Chen HW,Chang TC,Wang TH</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the prognostic value of the immunohistochemical expression of STIP1 in ovarian cancer</div> <div itemprodp="datePublished">Fri Aug 23 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23469227"> <div itemprop="name">Tissue engineered skin substitutes created by laser-assisted bioprinting form skin-like structures in the dorsal skin fold chamber in mice.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Michael S,Sorg H,Peck CT,Koch L,Deiwick A,Chichkov B,Vogt PM,Reimers K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the use of laser-assisted bioprinting to produce tissue engineered skin substitutes capable of forming skin-like structures</div> <div itemprodp="datePublished">Tue Aug 27 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24205004"> <div itemprop="name">Dmp1α inhibits HER2/neu-induced mammary tumorigenesis.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Fry EA,Taneja P,Maglic D,Zhu S,Sui G,Inoue K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which Dmp1-alpha blocks HER2-driven mammary tumorigenesis</div> <div itemprodp="datePublished">Thu Sep 04 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24459428"> <div itemprop="name">Biological and demographic profile of meningiomas in a cohort of Egyptian patients: impact on tumor recurrence.</div> </a> <div itemprop="about">TheScientificWorldJournal</div> <div itemprop="author">Abdelzaher E,El Deeb NM,Gowil AG,Yehya A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the relationship between meningioma biological and demographic profiles and disease recurrence in Egyptian patients</div> <div itemprodp="datePublished">Mon Jun 16 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24058595"> <div itemprop="name">TLR2 mediates Helicobacter pylori-induced tolerogenic immune response in mice.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Sun X,Zhang M,El-Zataari M,Owyang SY,Eaton KA,Liu M,Chang YM,Zou W,Kao JY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to assess the role of TLR2 in mediating H. pylori tolerogenic programming of dendritic cells.</div> <div itemprodp="datePublished">Mon Jun 16 00:00:00 EDT 2014</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22711276"> <div itemprop="name">Histone deacetylation inhibition in pulmonary hypertension: therapeutic potential of valproic acid and suberoylanilide hydroxamic acid.</div> </a> <div itemprop="about">Circulation</div> <div itemprop="author">Zhao L,Chen CN,Hajji N,Oliver E,Cotroneo E,Wharton J,Wang D,Li M,McKinsey TA,Stenmark KR,Wilkins MR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the therapeutic potential of HDAC inhibition in models of pulmonary hypertension</div> <div itemprodp="datePublished">Tue Jul 24 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22992515"> <div itemprop="name">Radioimmunotherapy of fibroblast activation protein positive tumors by rapidly internalizing antibodies.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Fischer E,Chaitanya K,Wüest T,Wadle A,Scott AM,van den Broek M,Schibli R,Bauer S,Renner C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the anti-tumor activity of radioimmunoconjugates of two rapidly internalizing antibodies recognizing FAP</div> <div itemprodp="datePublished">Thu Nov 15 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23052253"> <div itemprop="name">Highly specific targeting of the TMPRSS2/ERG fusion gene using liposomal nanovectors.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Shao L,Tekedereli I,Wang J,Yuca E,Tsang S,Sood A,Lopez-Berestein G,Ozpolat B,Ittmann M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the use of liposomal nanovectors for the specific targeting of siRNAs against the TMPRSS2-ERG fusion gene</div> <div itemprodp="datePublished">Sat Dec 15 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22573348"> <div itemprop="name">Targeting fibroblast growth factor receptor signaling inhibits prostate cancer progression.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Feng S,Shao L,Yu W,Gavine P,Ittmann M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the inhibition of prostate cancer progression by pharmacological blockade of FGF receptors</div> <div itemprodp="datePublished">Sun Jul 15 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22535157"> <div itemprop="name">A small-molecule inhibitor targeting the mitotic spindle checkpoint impairs the growth of uterine leiomyosarcoma.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Shan W,Akinfenwa PY,Savannah KB,Kolomeyevskaya N,Laucirica R,Thomas DG,Odunsi K,Creighton CJ,Lev DC,Anderson ML</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of a small-molecule inhibitor targeting the mitotic spindle checkpoint to inhibit uterine leiomyosarcoma growth</div> <div itemprodp="datePublished">Fri Jun 15 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22617445"> <div itemprop="name">Autophagy plays a critical role in kidney tubule maintenance, aging and ischemia-reperfusion injury.</div> </a> <div itemprop="about">Autophagy</div> <div itemprop="author">Liu S,Hartleben B,Kretz O,Wiech T,Igarashi P,Mizushima N,Walz G,Huber TB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of kidney tubular cell autophagy in the maintenance of kidney function under conditions of stress</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22651929"> <div itemprop="name">Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Jiang W,Zhu Z,McGinley JN,El Bayoumy K,Manni A,Thompson HJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the molecular changes associated with the dietary n-3 fatty acid-induced inhibition of mammary carcinoma growth</div> <div itemprodp="datePublished">Wed Aug 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23090068"> <div itemprop="name">Quantitative assessment of effect of preanalytic cold ischemic time on protein expression in breast cancer tissues.</div> </a> <div itemprop="about">Journal of the National Cancer Institute</div> <div itemprop="author">Neumeister VM,Anagnostou V,Siddiqui S,England AM,Zarrella ER,Vassilakopoulou M,Parisi F,Kluger Y,Hicks DG,Rimm DL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry and western blot to study the effect of the period of pre-analysis cold ischemia on the antigenicity of a number of breast cancer proteins</div> <div itemprodp="datePublished">Wed Dec 05 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22036880"> <div itemprop="name">Bioreducible polyethylenimine-delivered siRNA targeting human telomerase reverse transcriptase inhibits HepG2 cell growth in vitro and in vivo.</div> </a> <div itemprop="about">Journal of controlled release : official journal of the Controlled Release Society</div> <div itemprop="author">Xia W,Wang P,Lin C,Li Z,Gao X,Wang G,Zhao X</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the inhibition of HepG2 growth by knockdown of telomerase reverse transcriptase by siRNA delivered via a biodegradeable PEI-based carrier system</div> <div itemprodp="datePublished">Fri Feb 10 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22682017"> <div itemprop="name">Insulin-like growth factor type 1 receptor (IGF-1R) exclusive nuclear staining: a predictive biomarker for IGF-1R monoclonal antibody (Ab) therapy in sarcomas.</div> </a> <div itemprop="about">European journal of cancer (Oxford, England : 1990)</div> <div itemprop="author">Asmane I,Watkin E,Alberti L,Duc A,Marec-Berard P,Ray-Coquard I,Cassier P,Decouvelaere AV,Ranchère D,Kurtz JE,Bergerat JP,Blay JY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study exclusive nuclear IGF-R1 staining as a biomarker predictive of good response to IGF-1R monoclonal antibody therapy in sarcoma patients</div> <div itemprodp="datePublished">Thu Nov 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22786615"> <div itemprop="name">Promoting role of cholecystokinin 2 receptor (CCK2R) in gastrointestinal stromal tumour pathogenesis.</div> </a> <div itemprop="about">The Journal of pathology</div> <div itemprop="author">Quattrone A,Dewaele B,Wozniak A,Bauters M,Vanspauwen V,Floris G,Schöffski P,Chibon F,Coindre JM,Sciot R,Debiec-Rychter M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the cholecytokinin-2 receptor in promoting gastrointestinal stromal tumor tumorigenicity</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22776560"> <div itemprop="name">Mammary fibroblasts regulate morphogenesis of normal and tumorigenic breast epithelial cells by mechanical and paracrine signals.</div> </a> <div itemprop="about">Cancer letters</div> <div itemprop="author">Lühr I,Friedl A,Overath T,Tholey A,Kunze T,Hilpert F,Sebens S,Arnold N,Rösel F,Oberg HH,Maass N,Mundhenke C,Jonat W,Bauer M</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the mechanisms by which mammary fibroblasts regulate normal and tumorigenic breast epithelial cell morphogenesis</div> <div itemprodp="datePublished">Fri Dec 28 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22053853"> <div itemprop="name">Functional consequences of human airway smooth muscle phenotype plasticity.</div> </a> <div itemprop="about">British journal of pharmacology</div> <div itemprop="author">Dekkers BG,Bos IS,Zaagsma J,Meurs H</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the phenotypic plasticity of human airway smooth muscle cells and the significance for remodeling in asthma</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22531632"> <div itemprop="name">Quiescence and γH2AX in neuroblastoma are regulated by ouabain/Na,K-ATPase.</div> </a> <div itemprop="about">British journal of cancer</div> <div itemprop="author">Hiyoshi H,Abdelhady S,Segerström L,Sveinbjörnsson B,Nuriya M,Lundgren TK,Desfrere L,Miyakawa A,Yasui M,Kogner P,Johnsen JI,Andäng M,Uhlén P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the ouabain/Na,K-ATPase in regulating the growth of neuroblastoma cells</div> <div itemprodp="datePublished">Tue May 22 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22929883"> <div itemprop="name">WNT/β-catenin pathway activation in Myc immortalised cerebellar progenitor cells inhibits neuronal differentiation and generates tumours resembling medulloblastoma.</div> </a> <div itemprop="about">British journal of cancer</div> <div itemprop="author">Rogers HA,Sousa S,Salto C,Arenas E,Coyle B,Grundy RG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Wnt/beta-catenin pathway activity in the pathogenesis of medulloblastoma using a myc-immortalized cerebellar progenitor cell model</div> <div itemprodp="datePublished">Tue Sep 25 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22341270"> <div itemprop="name">Antitumor effects of cis-urocanic acid on experimental urothelial cell carcinoma of the bladder.</div> </a> <div itemprop="about">The Journal of urology</div> <div itemprop="author">Arentsen HC,Jansen CF,Hulsbergen-van de Kaa CA,Laihia JK,Pylkkänen L,Leino L,Oosterwijk E,Witjes JA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the anti-tumor effects of cis-urocanic acid on experimental urothelial cell carcinoma of the bladder.</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22763785"> <div itemprop="name">Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1.</div> </a> <div itemprop="about">The Journal of investigative dermatology</div> <div itemprop="author">Li J,Jiang TX,Hughes MW,Wu P,Yu J,Widelitz RB,Fan G,Chuong CM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of reduced stem cell activation in alopecia induced by deletion of DNA methyltransferase-1</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22170489"> <div itemprop="name">Overexpression of cathepsin S induces chronic atopic dermatitis in mice.</div> </a> <div itemprop="about">The Journal of investigative dermatology</div> <div itemprop="author">Kim N,Bae KB,Kim MO,Yu DH,Kim HJ,Yuh HS,Ji YR,Park SJ,Kim S,Son KH,Park SJ,Yoon D,Lee DS,Lee S,Lee HS,Kim TY,Ryoo ZY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the development of chronic atopic dermatitis in transgenic mice overexpressing cathepsin S</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22297634"> <div itemprop="name">IL-12 and IL-23 affect photocarcinogenesis differently.</div> </a> <div itemprop="about">The Journal of investigative dermatology</div> <div itemprop="author">Jantschitsch C,Weichenthal M,Proksch E,Schwarz T,Schwarz A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of IL-23 and IL-12 on UVR-induced tumorigenesis</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22241988"> <div itemprop="name">Lymphoid tissue damage in HIV-1 infection depletes naïve T cells and limits T cell reconstitution after antiretroviral therapy.</div> </a> <div itemprop="about">PLoS pathogens</div> <div itemprop="author">Zeng M,Southern PJ,Reilly CS,Beilman GJ,Chipman JG,Schacker TW,Haase AT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to test if damage to the lymphoid tissue fibroblastic reticular cell network contributes to naive T cell loss during HIV-1 infection</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22467332"> <div itemprop="name">Mice lacking epidermal PPARγ exhibit a marked augmentation in photocarcinogenesis associated with increased UVB-induced apoptosis, inflammation and barrier dysfunction.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Sahu RP,DaSilva SC,Rashid B,Martel KC,Jernigan D,Mehta SR,Mohamed DR,Rezania S,Bradish JR,Armstrong AB,Warren S,Konger RL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms underlying increased photocarcinogenesis in mice lacking epidermal PPAR gamma</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21413015"> <div itemprop="name">An intact retinoblastoma protein-binding site in Merkel cell polyomavirus large T antigen is required for promoting growth of Merkel cell carcinoma cells.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Houben R,Adam C,Baeurle A,Hesbacher S,Grimm J,Angermeyer S,Henzel K,Hauser S,Elling R,Bröcker EB,Gaubatz S,Becker JC,Schrama D</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the mechanism for the growth of Merkel cell carcinoma cells</div> <div itemprodp="datePublished">Wed Feb 15 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22190634"> <div itemprop="name">Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells.</div> </a> <div itemprop="about">Development (Cambridge, England)</div> <div itemprop="author">VanDussen KL,Carulli AJ,Keeley TM,Patel SR,Puthoff BJ,Magness ST,Tran IT,Maillard I,Siebel C,Kolterud Å,Grosse AS,Gumucio DL,Ernst SA,Tsai YH,Dempsey PJ,Samuelson LC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Notch in intestinal crypt base columnar stem cell proliferation and differentiation</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22159473"> <div itemprop="name">Collective action of hematopoietic cell subsets mediates anti-IL10R1 and CpG tumor immunity.</div> </a> <div itemprop="about">Cancer immunology, immunotherapy : CII</div> <div itemprop="author">Chou MY,Austin CD,Kim JM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of hematopoietic-derived cells in anti-IL10R1 and CpG tumor immunity</div> <div itemprodp="datePublished">Sun Jul 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22456610"> <div itemprop="name">The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.</div> </a> <div itemprop="about">The American journal of surgical pathology</div> <div itemprop="author">Lee CH,Mariño-Enriquez A,Ou W,Zhu M,Ali RH,Chiang S,Amant F,Gilks CB,van de Rijn M,Oliva E,Debiec-Rychter M,Dal Cin P,Fletcher JA,Nucci MR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on the clinical and pathological features of 13 cases of YWHAE-FAM22 endometrial stromal sarcoma</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22143518"> <div itemprop="name">Chemotherapy-associated changes of histopathological features of Mycobacterium ulcerans lesions in a Buruli ulcer mouse model.</div> </a> <div itemprop="about">Antimicrobial agents and chemotherapy</div> <div itemprop="author">Ruf MT,Schütte D,Chauffour A,Jarlier V,Ji B,Pluschke G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of chemotherapy on the infection lesions of M. ulcerans in a mouse model</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22935140"> <div itemprop="name">Expression of constitutively active FoxO3 in murine forebrain leads to a loss of neural progenitors.</div> </a> <div itemprop="about">FASEB journal : official publication of the Federation of American Societies for Experimental Biology</div> <div itemprop="author">Schmidt-Strassburger U,Schips TG,Maier HJ,Kloiber K,Mannella F,Braunstein KE,Holzmann K,Ushmorov A,Liebau S,Boeckers TM,Wirth T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which transgenic expression of constitutively active FoxO3 leads to enhanced apoptosis and loss of forebrain neural progenitors in mice</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22632819"> <div itemprop="name">YAP promotes breast cell proliferation and survival partially through stabilizing the KLF5 transcription factor.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Zhi X,Zhao D,Zhou Z,Liu R,Chen C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the KLF5 transcription factor in the mechanism by which YAP promotes the proliferation and survival of breast cells</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23036899"> <div itemprop="name">Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Syu LJ,El-Zaatari M,Eaton KA,Liu Z,Tetarbe M,Keeley TM,Pero J,Ferris J,Wilbert D,Kaatz A,Zheng X,Qiao X,Grachtchouk M,Gumucio DL,Merchant JL,Samuelson LC,Dlugosz AA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the induction of inflammation, metaplasia and displasia following transgenic expression of IFN-gamma in the murine stomach</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22819724"> <div itemprop="name">Blockage of lysophosphatidic acid signaling improves spinal cord injury outcomes.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Goldshmit Y,Matteo R,Sztal T,Ellett F,Frisca F,Moreno K,Crombie D,Lieschke GJ,Currie PD,Sabbadini RA,Pébay A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the beneficial effects of an anti-lysophasphatidic acid antibody in models of spinal cord injury</div> <div itemprodp="datePublished">Sat Sep 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22503752"> <div itemprop="name">Endometrial tumorigenesis in Pten(+/-) mice is independent of coexistence of estrogen and estrogen receptor α.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Joshi A,Wang H,Jiang G,Douglas W,Chan JS,Korach KS,Ellenson LH</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry and western blot to study endometrial tumorigenesis in heterozygous Pten (+/-) mice and the relationship with estrogen signaling</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22440256"> <div itemprop="name">Yin Yang 1 plays an essential role in breast cancer and negatively regulates p27.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Wan M,Huang W,Kute TE,Miller LD,Zhang Q,Hatcher H,Wang J,Stovall DB,Russell GB,Cao PD,Deng Z,Wang W,Zhang Q,Lei M,Torti SV,Akman SA,Sui G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of p27 in the oncogenic activity of Yin Yang-1 in breast cancer</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22105852"> <div itemprop="name">Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity.</div> </a> <div itemprop="about">Journal of molecular medicine (Berlin, Germany)</div> <div itemprop="author">Yang SB,Lee HY,Young DM,Tien AC,Rowson-Baldwin A,Shu YY,Jan YN,Jan LY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms underlying the induction of glucose intolerance in mice by rapamycin</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22223359"> <div itemprop="name">Targeting colorectal cancer stem cells with inducible caspase-9.</div> </a> <div itemprop="about">Apoptosis : an international journal on programmed cell death</div> <div itemprop="author">Kemper K,Rodermond H,Colak S,Grandela C,Medema JP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the influence of dimerization of inducible caspase-9 in colorectal cancer stem cells</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22799489"> <div itemprop="name">Nanostructured porous silicon micropatterns as a tool for substrate-conditioned cell research.</div> </a> <div itemprop="about">Nanoscale research letters</div> <div itemprop="author">Punzón-Quijorna E,Sánchez-Vaquero V,Muñoz-Noval A,Pérez-Roldán MJ,Martín-Palma RJ,Rossi F,Climent-Font A,Manso-Silván M,Ruiz JP,Torres-Costa V</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study nanostructured porous silicon micropatterns as a tool for substrate-conditioned cell research</div> <div itemprodp="datePublished">Mon Jul 16 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22086855"> <div itemprop="name">Association of aberrations in one-carbon metabolism with molecular phenotype and grade of breast cancer.</div> </a> <div itemprop="about">Molecular carcinogenesis</div> <div itemprop="author">Naushad SM,Pavani A,Rupasree Y,Divyya S,Deepti S,Digumarti RR,Gottumukkala SR,Prayaga A,Kutala VK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate one-carbon metabolism dysfunction in breast cancer progression</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22518061"> <div itemprop="name">The adult pituitary shows stem/progenitor cell activation in response to injury and is capable of regeneration.</div> </a> <div itemprop="about">Endocrinology</div> <div itemprop="author">Fu Q,Gremeaux L,Luque RM,Liekens D,Chen J,Buch T,Waisman A,Kineman R,Vankelecom H</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry and immunohistochemistry to study the ability of stem/progenitor cells to promote regeneration of the adult pituitary following injury</div> <div itemprodp="datePublished">Sun Jul 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22766853"> <div itemprop="name">Conditional deletion of menin results in antral G cell hyperplasia and hypergastrinemia.</div> </a> <div itemprop="about">American journal of physiology. Gastrointestinal and liver physiology</div> <div itemprop="author">Veniaminova NA,Hayes MM,Varney JM,Merchant JL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the increase in the number of antral G cells and antrum gastrin expression in response to conditional ablation of menin</div> <div itemprodp="datePublished">Sat Sep 15 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21999525"> <div itemprop="name">Failure of delayed intravenous administration of bone marrow stromal cells after traumatic brain injury.</div> </a> <div itemprop="about">Journal of neurotrauma</div> <div itemprop="author">Bonilla C,Zurita M,Otero L,Aguayo C,Rico MA,Rodríguez A,Vaquero J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of injection of bone marrow stromal cells on tramautic brain injury following the establishment of neurological deficits</div> <div itemprodp="datePublished">Fri Jan 20 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23323157"> <div itemprop="name">Evidence of mTOR Activation by an AKT-Independent Mechanism Provides Support for the Combined Treatment of PTEN-Deficient Prostate Tumors with mTOR and AKT Inhibitors.</div> </a> <div itemprop="about">Translational oncology</div> <div itemprop="author">Zhang W,Haines BB,Efferson C,Zhu J,Ware C,Kunii K,Tammam J,Angagaw M,Hinton MC,Keilhack H,Paweletz CP,Zhang T,Winter C,Sathyanarayanan S,Cheng J,Zawel L,Fawell S,Gilliland G,Majumder PK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study Akt-indepenedent mTOR activation in a model of PTEN-deficient prostate cancer and the therapeutic potential of combining both mTOR and Akt inhibitors</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22072617"> <div itemprop="name">Cell signaling pathways associated with a reduction in mammary cancer burden by dietary common bean (Phaseolus vulgaris L.).</div> </a> <div itemprop="about">Carcinogenesis</div> <div itemprop="author">Thompson MD,Mensack MM,Jiang W,Zhu Z,Lewis MR,McGinley JN,Brick MA,Thompson HJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the mechanism of bean food-induced breast cancer inhibition</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21509526"> <div itemprop="name">KX-01, a novel Src kinase inhibitor directed toward the peptide substrate site, synergizes with tamoxifen in estrogen receptor α positive breast cancer.</div> </a> <div itemprop="about">Breast cancer research and treatment</div> <div itemprop="author">Anbalagan M,Carrier L,Glodowski S,Hangauer D,Shan B,Rowan BG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the synergistic effects against estrogen receptor-alpha-positive breast cancer of a peptidomimetic Src kinase inhibitor and tamoxifen</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22079257"> <div itemprop="name">Insights antifibrotic mechanism of methyl palmitate: impact on nuclear factor kappa B and proinflammatory cytokines.</div> </a> <div itemprop="about">Toxicology and applied pharmacology</div> <div itemprop="author">Mantawy EM,Tadros MG,Awad AS,Hassan DA,El-Demerdash E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the antifibrotic mechanism of methyl palmitate</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22970885"> <div itemprop="name">Regenerative capacity of the adult pituitary: multiple mechanisms of lactotrope restoration after transgenic ablation.</div> </a> <div itemprop="about">Stem cells and development</div> <div itemprop="author">Fu Q,Vankelecom H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms underlying lactotrope repair in transgenically ablated adult murine pituitary</div> <div itemprodp="datePublished">Mon Dec 10 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22646081"> <div itemprop="name">Mechanical environment modulates biological properties of oligodendrocyte progenitor cells.</div> </a> <div itemprop="about">Stem cells and development</div> <div itemprop="author">Jagielska A,Norman AL,Whyte G,Vliet KJ,Guck J,Franklin RJ</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the modulation of the properties of oligodendrocyte progenitors by the mechanical properties of their growth substrate</div> <div itemprodp="datePublished">Thu Nov 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22396001"> <div itemprop="name">HOXB9 expression promoting tumor cell proliferation and angiogenesis is associated with clinical outcomes in breast cancer patients.</div> </a> <div itemprop="about">Annals of surgical oncology</div> <div itemprop="author">Seki H,Hayashida T,Jinno H,Hirose S,Sakata M,Takahashi M,Maheswaran S,Mukai M,Kitagawa Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the prognostic value of HOXB9 expression in breast cancer</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22459607"> <div itemprop="name">Effects of acrylamide exposure on serum hormones, gene expression, cell proliferation, and histopathology in male reproductive tissues of Fischer 344 rats.</div> </a> <div itemprop="about">Toxicology letters</div> <div itemprop="author">Camacho L,Latendresse JR,Muskhelishvili L,Patton R,Bowyer JF,Thomas M,Doerge DR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of acrylamide exposure on reproductive tissues and hypothalamic-pituitary-testes axis</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22419448"> <div itemprop="name">Susceptibility loci affecting ERBB2/neu-induced mammary tumorigenesis in mice.</div> </a> <div itemprop="about">Genes, chromosomes & cancer</div> <div itemprop="author">Quan L,Dittmar A,Zhou Y,Hutson A,Stassen AP,Demant P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to identify susceptibility loci that affect ERBB2/neu-induced mammary tumorigenesis in mice</div> <div itemprodp="datePublished">Sun Jul 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21976597"> <div itemprop="name">Temporal differences in granulosa cell specification in the ovary reflect distinct follicle fates in mice.</div> </a> <div itemprop="about">Biology of reproduction</div> <div itemprop="author">Mork L,Maatouk DM,McMahon JA,Guo JJ,Zhang P,McMahon AP,Capel B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the time course of granulosa cell specification in the murine ovary</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22364180"> <div itemprop="name">Bimodal effect of retinoic acid on melanocyte differentiation identified by time-dependent analysis.</div> </a> <div itemprop="about">Pigment cell & melanoma research</div> <div itemprop="author">Inoue Y,Hasegawa S,Yamada T,Date Y,Mizutani H,Nakata S,Matsunaga K,Akamatsu H</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the effects of retinoic acid on melanocytes at each stage of differentiation</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22305181"> <div itemprop="name">Fates of murine pluripotent stem cell-derived neural progenitors following transplantation into mouse cochleae.</div> </a> <div itemprop="about">Cell transplantation</div> <div itemprop="author">Nishimura K,Nakagawa T,Sakamoto T,Ito J</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the tumorigenic risk associated with the cochleal transplantaion of neural progenitors derived from mouse pluripotent stem cells</div> <div itemprodp="datePublished">Tue Jun 25 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22301622"> <div itemprop="name">PTEN loss defines a TGF-β-induced tubule phenotype of failed differentiation and JNK signaling during renal fibrosis.</div> </a> <div itemprop="about">American journal of physiology. Renal physiology</div> <div itemprop="author">Lan R,Geng H,Polichnowski AJ,Singha PK,Saikumar P,McEwen DG,Griffin KA,Koesters R,Weinberg JM,Bidani AK,Kriz W,Venkatachalam MA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the involvement of PTEN in fibrosis after renal repair</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22129965"> <div itemprop="name">De novo expression of podocyte proteins in parietal epithelial cells in experimental aging nephropathy.</div> </a> <div itemprop="about">American journal of physiology. Renal physiology</div> <div itemprop="author">Zhang J,Hansen KM,Pippin JW,Chang AM,Taniguchi Y,Krofft RD,Pickering SG,Liu ZH,Abrass CK,Shankland SJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the expression of podocyte-specific proteins by parietal epithelial cells during experimental aging nephropathy</div> <div itemprodp="datePublished">Thu Mar 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22072572"> <div itemprop="name">Carbidopa enhances antitumoral activity of bicalutamide on the androgen receptor-axis in castration-resistant prostate tumors.</div> </a> <div itemprop="about">The Prostate</div> <div itemprop="author">Thomas C,Wafa LA,Lamoureux F,Cheng H,Fazli L,Gleave ME,Rennie PS</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of carbidopa on the antitumoral activity of bicalutamide in the androgen receptor-axis in castration-resistant prostate tumors</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22337223"> <div itemprop="name">The effects of intrauterine growth restriction and antenatal glucocorticoids on ovine fetal lung development.</div> </a> <div itemprop="about">Pediatric research</div> <div itemprop="author">Sutherland AE,Crossley KJ,Allison BJ,Jenkin G,Wallace EM,Miller SL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study fetal lung development in sheep and the effects of intrauterine growth restriction and glucocorticoid administration</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22465407"> <div itemprop="name">Activation of neural progenitor cells in human eyes with proliferative vitreoretinopathy.</div> </a> <div itemprop="about">Experimental eye research</div> <div itemprop="author">Johnsen EO,Frøen RC,Albert R,Omdal BK,Sarang Z,Berta A,Nicolaissen B,Petrovski G,Moe MC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study whether neural stem/progenitor cells can be activated in human eyes suffering proliferative vitreoretinopathy</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21080410"> <div itemprop="name">Increased adult hippocampal neurogenesis and abnormal migration of adult-born granule neurons is associated with hippocampal-specific cognitive deficits in phospholipase C-β1 knockout mice.</div> </a> <div itemprop="about">Hippocampus</div> <div itemprop="author">Manning EE,Ransome MI,Burrows EL,Hannan AJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the cellular mechanisms linking PLC-beta1 knockout to schizophrenia-like behavior</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22558965"> <div itemprop="name">Effect of staged ovariectomy on measures of mammary growth and development in prepubertal dairy heifers.</div> </a> <div itemprop="about">Animal : an international journal of animal bioscience</div> <div itemprop="author">Velayudhan BT,Huderson BP,McGilliard ML,Jiang H,Ellis SE,Akers RM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of staged ovariectomy on mammary growth and development in prepubertal dairy heifers</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23113595"> <div itemprop="name">Compton scattering by internal shields based on melanin-containing mushrooms provides protection of gastrointestinal tract from ionizing radiation.</div> </a> <div itemprop="about">Cancer biotherapy & radiopharmaceuticals</div> <div itemprop="author">Revskaya E,Chu P,Howell RC,Schweitzer AD,Bryan RA,Harris M,Gerfen G,Jiang Z,Jandl T,Kim K,Ting LM,Sellers RS,Dadachova E,Casadevall A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of oral administration of mushrooms containing melanin to protect the gut against ionizing radiation</div> <div itemprodp="datePublished">Thu Nov 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22323293"> <div itemprop="name">Intermediate progenitors are increased by lengthening of the cell cycle through calcium signaling and p53 expression in human neural progenitors.</div> </a> <div itemprop="about">Molecular biology of the cell</div> <div itemprop="author">García-García E,Pino-Barrio MJ,López-Medina L,Martínez-Serrano A</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the role of Ca(2+) signaling and p53 activation in the generation of intermediate progenitors from human neural progenitor cells</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21744088"> <div itemprop="name">Somatotroph pituitary adenoma with acromegaly and autosomal dominant polycystic kidney disease: SSTR5 polymorphism and PKD1 mutation.</div> </a> <div itemprop="about">Pituitary</div> <div itemprop="author">Syro LV,Sundsbak JL,Scheithauer BW,Toledo RA,Camargo M,Heyer CM,Sekiya T,Uribe H,Escobar JI,Vasquez M,Rotondo F,Toledo SP,Kovacs K,Horvath E,Babovic-Vuksanovic D,Harris PC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of somatotroph pituitary adenoma presenting with acromegaly and autosomal dominant polycystic kidney disease</div> <div itemprodp="datePublished">Sat Sep 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22818167"> <div itemprop="name">BCL10 down-regulation in peripheral T-cell lymphomas.</div> </a> <div itemprop="about">Human pathology</div> <div itemprop="author">Rossi M,Agostinelli C,Righi S,Sabattini E,Bacci F,Gazzola A,Pileri SA,Piccaluga PP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the down-regulation of BCL10 in peripheral T-cell lymphomas</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23257686"> <div itemprop="name">Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression.</div> </a> <div itemprop="about">Developmental neuroscience</div> <div itemprop="author">Choe Y,Pleasure SJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of CXCR4 in the mechanism by which Wnt modulates the production of intermediate precursors in the dentate gyrus of neonates</div> <div itemprodp="datePublished">Thu Sep 19 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22277792"> <div itemprop="name">Evaluation of apoptosis along with BCL-2 and Ki-67 expression in patients with intestinal metaplasia.</div> </a> <div itemprop="about">Pathology, research and practice</div> <div itemprop="author">Erkan G,Gonul II,Kandilci U,Dursun A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study BCL-2 and Ki-67 expression and apoptotic status in patients with intestinal metaplasia</div> <div itemprodp="datePublished">Wed Feb 15 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22318127"> <div itemprop="name">Expression and activation of EphA4 in the human brain after traumatic injury.</div> </a> <div itemprop="about">Journal of neuropathology and experimental neurology</div> <div itemprop="author">Frugier T,Conquest A,McLean C,Currie P,Moses D,Goldshmit Y</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the effect of traumatic brain injury on EphA4 expression and activation in humans</div> <div itemprodp="datePublished">Thu Mar 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22705479"> <div itemprop="name">Testis development requires the repression of Wnt4 by Fgf signaling.</div> </a> <div itemprop="about">Developmental biology</div> <div itemprop="author">Jameson SA,Lin YT,Capel B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Wnt repression in testicular development and the role played by Fgf signaling pathways</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22209769"> <div itemprop="name">Comparative morphological and immunohistochemical study of human meningioma after intracranial transplantation into nude mice.</div> </a> <div itemprop="about">Journal of neuroscience methods</div> <div itemprop="author">Friedrich S,Schwabe K,Klein R,Krusche CA,Krauss JK,Nakamura M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the morphology and immunohistochemistry of human meningioma after intracranial transplantation into nude mice</div> <div itemprodp="datePublished">Fri Mar 30 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22837015"> <div itemprop="name">Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons.</div> </a> <div itemprop="about">Developmental dynamics : an official publication of the American Association of Anatomists</div> <div itemprop="author">Pacal M,Bremner R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop a high resolution map of the kinetics of differentiation of murine retinal newborn neurons</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21848935"> <div itemprop="name">Electrospun small-diameter polyurethane vascular grafts: ingrowth and differentiation of vascular-specific host cells.</div> </a> <div itemprop="about">Artificial organs</div> <div itemprop="author">Bergmeister H,Grasl C,Walter I,Plasenzotti R,Stoiber M,Schreiber C,Losert U,Weigel G,Schima H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the performance of small diameter microspun vascular grafts made of polyurethane in a rat model</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20869070"> <div itemprop="name">Quantitative assessment of liver function after ischemia-reperfusion injury and partial hepatectomy in rats.</div> </a> <div itemprop="about">The Journal of surgical research</div> <div itemprop="author">de Graaf W,Heger M,Spruijt O,Maas A,de Bruin K,Hoekstra R,Bennink RJ,van Gulik TM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to measure liver function following ischemia-reperfusion injury and partial hepatectomy in rats</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22359222"> <div itemprop="name">Increased FDG uptake in breast cancer is associated with prognostic factors.</div> </a> <div itemprop="about">Annals of nuclear medicine</div> <div itemprop="author">Sanli Y,Kuyumcu S,Ozkan ZG,Işik G,Karanlik H,Guzelbey B,Turkmen C,Ozel S,Yavuz E,Mudun A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the relationship between FDG uptake and prognostic factors in breast cancer</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22269660"> <div itemprop="name">Late embryonic and postnatal development of interstitial cells of cajal in mouse esophagus: distribution, proliferation and kit dependence.</div> </a> <div itemprop="about">Cells, tissues, organs</div> <div itemprop="author">He X,Yang WC,Wen XY,Tang D,Xiao L,Han J,Yu B,Zhang W,Mei F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the development of murine esophageal interstitial cells of cajal through the late embryonic and early post-natal stages</div> <div itemprodp="datePublished">Thu Jan 17 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22192803"> <div itemprop="name">Primary pure squamous cell carcinoma of the thyroid: report and histogenic consideration of a case involving a BRAF mutation.</div> </a> <div itemprop="about">Pathology international</div> <div itemprop="author">Ko YS,Hwang TS,Han HS,Lim SD,Kim WS,Oh SY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study a case of primary squamous cell carcinoma of the thyroid</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22344361"> <div itemprop="name">Paraganglioma of seminal vesicle and chromophobe renal cell carcinoma: a case report and literature review.</div> </a> <div itemprop="about">Sao Paulo medical journal = Revista paulista de medicina</div> <div itemprop="author">Alvarenga CA,Lopes JM,Vinagre J,Paravidino PI,Alvarenga M,Prando A,Castilho LN,Soares P,Billis A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of paraganglioma of seminal vesicle and chromophobe renal cell carcinoma</div> <div itemprodp="datePublished">Thu Oct 04 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21859382"> <div itemprop="name">Honey as a substitute for formalin?</div> </a> <div itemprop="about">Biotechnic & histochemistry : official publication of the Biological Stain Commission</div> <div itemprop="author">Ozkan N,Salva E,Cakalağaoğlu F,Tüzüner B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate honey as an alternative to formalin in histopathological examination</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22841956"> <div itemprop="name">Rgs19 regulates mouse palatal fusion by modulating cell proliferation and apoptosis in the MEE.</div> </a> <div itemprop="about">Mechanisms of development</div> <div itemprop="author">Sohn WJ,Ji YR,Kim HS,Gwon GJ,Chae YM,An CH,Park HD,Jung HS,Ryoo ZY,Lee S,Kim JY</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which Rgs19 regulates mouse palatal fusion</div> <div itemprodp="datePublished">Wed Jun 12 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22666755"> <div itemprop="name">Combination hyperbaric oxygen and temozolomide therapy in C6 rat glioma model.</div> </a> <div itemprop="about">Acta cirurgica brasileira</div> <div itemprop="author">Dagıstan Y,Karaca I,Bozkurt ER,Ozar E,Yagmurlu K,Toklu A,Bilir A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of hyperbaric oxygen and temozolomide in a rat rat model of glioma</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22841260"> <div itemprop="name">No harmful effect of mycophenolate mofetil on liver regeneration: an experimental study.</div> </a> <div itemprop="about">Transplantation proceedings</div> <div itemprop="author">Demiray M,Kucuk HF,Yildirim M,Barisik NO</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of mycophenolate mofetil on liver regeneration following partial hepatectomy</div> <div itemprodp="datePublished">Thu Jan 03 00:00:00 EST 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22665006"> <div itemprop="name">Cauda equina paraganglioma with ependymoma-like histology: a case report.</div> </a> <div itemprop="about">Turkish neurosurgery</div> <div itemprop="author">Midi A,Yener AN,Sav A,Cubuk R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of cauda equina paraganglioma</div> <div itemprodp="datePublished">Thu Nov 29 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22808560"> <div itemprop="name">Early changes in carcinogenesis of colorectal adenomas.</div> </a> <div itemprop="about">The West Indian medical journal</div> <div itemprop="author">Toru S,Bilezikçi B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study early changes and high risk factors in carcinogenesis of colorectal adenomas</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22736949"> <div itemprop="name">Oxidative stress gradient in a medium during human corneal organ culture.</div> </a> <div itemprop="about">Molecular vision</div> <div itemprop="author">Johnsen-Soriano S,Haug K,Arnal E,Peris-Martinez C,Moe MC,Romero FJ,Nicolaissen B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the establishment of an oxidative stress gradient in storage vials during corneal organ culture</div> <div itemprodp="datePublished">Tue Nov 13 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22994740"> <div itemprop="name">MSP58 knockdown inhibits the proliferation of esophageal squamous cell carcinoma in vitro and in vivo.</div> </a> <div itemprop="about">Asian Pacific journal of cancer prevention : APJCP</div> <div itemprop="author">Xu CS,Zheng JY,Zhang HL,Zhao HD,Zhang J,Wu GQ,Wu L,Wang Q,Wang WZ,Zhang J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the inhibition of esophageal squamous cell carcinoma proliferation by shRNA-mediated knockdown of MSP58</div> <div itemprodp="datePublished">Mon Jun 03 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21956171"> <div itemprop="name">Knockdown of ubiquitin ligases in glioblastoma cancer stem cells leads to cell death and differentiation.</div> </a> <div itemprop="about">Journal of biomolecular screening</div> <div itemprop="author">Low J,Blosser W,Dowless M,Ricci-Vitiani L,Pallini R,de Maria R,Stancato L</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the induction of glioblastoma cancer stem cell death and differentiation following shRNA knockdown of ubiquitin ligases</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22497861"> <div itemprop="name">Sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression: report of a case and literature review.</div> </a> <div itemprop="about">Diagnostic pathology</div> <div itemprop="author">Yin WH,Li J,Chan JK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of sporadic haemangioblastoma of the kidney with rhabdoid features and focal CD10 expression</div> <div itemprodp="datePublished">Thu Apr 12 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22685290"> <div itemprop="name">Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Du Y,Kong G,You X,Zhang S,Zhang T,Gao Y,Ye L,Zhang X</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the increase in HULC mediated by hepatitis B virus X protein and its role in hepatoma cell proliferation</div> <div itemprodp="datePublished">Fri Jul 27 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22741527"> <div itemprop="name">Pigmented paraganglioma of the kidney: a case report.</div> </a> <div itemprop="about">Diagnostic pathology</div> <div itemprop="author">Zhao L,Luo J,Zhang H,Da J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of pigmented paraganglioma of the kidney</div> <div itemprodp="datePublished">Thu Jun 28 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23110168"> <div itemprop="name">Inflammation and Gli2 suppress gastrin gene expression in a murine model of antral hyperplasia.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Saqui-Salces M,Covés-Datson E,Veniaminova NA,Waghray M,Syu LJ,Dlugosz AA,Merchant JL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms underlying the inhibition of gastrin expression by inflammation and Gli2 in an animal model of antral hyperplasia</div> <div itemprodp="datePublished">Fri Apr 05 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22363530"> <div itemprop="name">Proteomic analyses reveal high expression of decorin and endoplasmin (HSP90B1) are associated with breast cancer metastasis and decreased survival.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Cawthorn TR,Moreno JC,Dharsee M,Tran-Thanh D,Ackloo S,Zhu PH,Sardana G,Chen J,Kupchak P,Jacks LM,Miller NA,Youngson BJ,Iakovlev V,Guidos CJ,Vallis KA,Evans KR,McCready D,Leong WL,Done SJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to identify prognostic biomarkers in breast cancer patients using proteomoc analysis</div> <div itemprodp="datePublished">Fri Jun 29 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22235978"> <div itemprop="name">Early onset of endothelial cell proliferation in coronary thrombi of patients with an acute myocardial infarction: implications for plaque healing.</div> </a> <div itemprop="about">Journal of thrombosis and haemostasis : JTH</div> <div itemprop="author">Li X,Kramer MC,VAN DER Loos CM,Ploegmakers HJ,DE Boer OJ,Koch KT,Tijssen JG,DE Winter RJ,VAN DER Wal AC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study neovascularization and the timing of endothelial cell proliferation in coronary thrombi following acute myocardial infarction</div> <div itemprodp="datePublished">Thu Mar 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23153292"> <div itemprop="name">Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments.</div> </a> <div itemprop="about">BMC cancer</div> <div itemprop="author">Nguyen L,Fifis T,Malcontenti-Wilson C,Chan LS,Costa PN,Nikfarjam M,Muralidharan V,Christophi C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to characterize the inherent differences in the microenvironment of the tumor periphery that contribute to OXi4503 treatment resistance</div> <div itemprodp="datePublished">Thu Nov 15 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22242181"> <div itemprop="name">The homeobox gene Gsx2 regulates the self-renewal and differentiation of neural stem cells and the cell fate of postnatal progenitors.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Méndez-Gómez HR,Vicario-Abejón C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the Gsx2 transcription factor in modulating neural stem cell self-renewal and differentiation</div> <div itemprodp="datePublished">Tue May 08 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23029204"> <div itemprop="name">Overexpression of miR-30b in the developing mouse mammary gland causes a lactation defect and delays involution.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Le Guillou S,Sdassi N,Laubier J,Passet B,Vilotte M,Castille J,Laloë D,Polyte J,Bouet S,Jaffrézic F,Cribiu EP,Vilotte JL,Le Provost F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the defective lactation and delayed involution observed in the developing mammary gland of mice transgenically overexpressing miRNA-30b</div> <div itemprodp="datePublished">Thu Mar 28 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23109924"> <div itemprop="name">Is primary pulmonary meningioma a giant form of a meningothelial-like nodule? A case report and review of the literature.</div> </a> <div itemprop="about">Case reports in oncology</div> <div itemprop="author">Masago K,Hosada W,Sasaki E,Murakami Y,Sugano M,Nagasaka T,Yamada M,Yatabe Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a patient with large pulmonary meningothelial-like nodules</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22078264"> <div itemprop="name">Differential function of NBS1 and ATR in neurogenesis.</div> </a> <div itemprop="about">DNA repair</div> <div itemprop="author">Zhou Z,Bruhn C,Wang ZQ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the different neurogenic roles of NBS1 and ATR</div> <div itemprodp="datePublished">Wed Feb 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22363671"> <div itemprop="name">Reduced proliferation in the adult mouse subventricular zone increases survival of olfactory bulb interneurons.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Sui Y,Horne MK,Stanić D</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to test if survival of adult-born cells is regulated by the rate of precursor proliferation in the subependymal zone</div> <div itemprodp="datePublished">Fri Jun 29 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21558842"> <div itemprop="name">The prognostic value of Skp2 expression in Egyptian diffuse large B-cell lymphoma.</div> </a> <div itemprop="about">Applied immunohistochemistry & molecular morphology : AIMM</div> <div itemprop="author">Abdou AG,Asaad NY,Abd El-Wahed MM,Samaka RM,Allah MS</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study Skp2 expression and its prognostic value in Egyptian diffuse large B-cell lymphoma</div> <div itemprodp="datePublished">Sun Jan 01 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/23248743"> <div itemprop="name">Cdc42-dependent structural development of auditory supporting cells is required for wound healing at adulthood.</div> </a> <div itemprop="about">Scientific reports</div> <div itemprop="author">Anttonen T,Kirjavainen A,Belevich I,Laos M,Richardson WD,Jokitalo E,Brakebusch C,Pirvola U</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of Cdc42 ablation on auditory supporting cells and adult wound healing</div> <div itemprodp="datePublished">Fri Jun 14 00:00:00 EDT 2013</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22701178"> <div itemprop="name">A crucial role of bone morphogenetic protein signaling in the wound healing response in acute liver injury induced by carbon tetrachloride.</div> </a> <div itemprop="about">International journal of hepatology</div> <div itemprop="author">Oumi N,Taniguchi KA,Kanai AM,Yasunaga M,Nakanishi T,Sato K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of BMP signaling in wound repair in a rat model of acute hepatic injury</div> <div itemprodp="datePublished">Thu Aug 23 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/24213469"> <div itemprop="name">Characterization of the Tumor-Microenvironment in Patient-Derived Cervix Xenografts (OCICx).</div> </a> <div itemprop="about">Cancers</div> <div itemprop="author">Chaudary N,Pintilie M,Schwock J,Dhani N,Clarke B,Milosevic M,Fyles A,Hill RP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to discuss how the microenvironmental properties of primary tumors are recapitulated in xenograft models</div> <div itemprodp="datePublished">Wed Aug 29 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21572435"> <div itemprop="name">COP1 is a tumour suppressor that causes degradation of ETS transcription factors.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Vitari AC,Leong KG,Newton K,Yee C,O'Rourke K,Liu J,Phu L,Vij R,Ferrando R,Couto SS,Mohan S,Pandita A,Hongo JA,Arnott D,Wertz IE,Gao WQ,French DM,Dixit VM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate post-translational regulation of ETS family and their roles in prostatic tumorgenesis</div> <div itemprodp="datePublished">Sun May 15 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21459094"> <div itemprop="name">Differentiated human colorectal cancer cells protect tumor-initiating cells from irinotecan.</div> </a> <div itemprop="about">Gastroenterology</div> <div itemprop="author">Emmink BL,Van Houdt WJ,Vries RG,Hoogwater FJ,Govaert KM,Verheem A,Nijkamp MW,Steller EJ,Jimenez CR,Clevers H,Borel Rinkes IH,Kranenburg O</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the association of tumor-initiating potential with irinotecan resistance in human colorectal cancer cells</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21993848"> <div itemprop="name">IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.</div> </a> <div itemprop="about">Nature immunology</div> <div itemprop="author">Ramirez-Carrozzi V,Sambandam A,Luis E,Lin Z,Jeet S,Lesch J,Hackney J,Kim J,Zhou M,Lai J,Modrusan Z,Sai T,Lee W,Xu M,Caplazi P,Diehl L,de Voss J,Balazs M,Gonzalez L,Singh H,Ouyang W,Pappu R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of IL-17C on the non-specific immune response of epithelial cells</div> <div itemprodp="datePublished">Wed Oct 12 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21519145"> <div itemprop="name">Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Grachtchouk M,Pero J,Yang SH,Ermilov AN,Michael LE,Wang A,Wilbert D,Patel RM,Ferris J,Diener J,Allen M,Lim S,Syu LJ,Verhaegen M,Dlugosz AA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the origin of basal cell carcinomas</div> <div itemprodp="datePublished">Sun May 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21734641"> <div itemprop="name">Fibrinogen, acting as a mitogen for tubulointerstitial fibroblasts, promotes renal fibrosis.</div> </a> <div itemprop="about">Kidney international</div> <div itemprop="author">Sörensen I,Susnik N,Inhester T,Degen JL,Melk A,Haller H,Schmitt R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of fibrinogen in renal fibrosis</div> <div itemprodp="datePublished">Tue Nov 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22038993"> <div itemprop="name">Predicting IGF-1R therapy response in bone sarcomas: immuno-SPECT imaging with radiolabeled R1507.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Fleuren ED,Versleijen-Jonkers YM,van de Luijtgaarden AC,Molkenboer-Kuenen JD,Heskamp S,Roeffen MH,van Laarhoven HW,Houghton PJ,Oyen WJ,Boerman OC,van der Graaf WT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop a novel non-invasive method to help predict the response of bone sarcomas to IGF-1R therapy</div> <div itemprodp="datePublished">Thu Dec 15 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21540235"> <div itemprop="name">Delineation of a cellular hierarchy in lung cancer reveals an oncofetal antigen expressed on tumor-initiating cells.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Damelin M,Geles KG,Follettie MT,Yuan P,Baxter M,Golas J,DiJoseph JF,Karnoub M,Huang S,Diesl V,Behrens C,Choe SE,Rios C,Gruzas J,Sridharan L,Dougher M,Kunz A,Hamann PR,Evans D,Armellino D,Khandke K,Marquette K,Tchistiakova L,Boghaert ER,Abraham RT,Wistuba II,Zhou BB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the heterogeneity and hierarchy in non-small cell lung cancer cells</div> <div itemprodp="datePublished">Wed Jun 15 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21482677"> <div itemprop="name">Luminal expression of PIK3CA mutant H1047R in the mammary gland induces heterogeneous tumors.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Meyer DS,Brinkhaus H,Müller U,Müller M,Cardiff RD,Bentires-Alj M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to elucidate the contribution of PIK3CA H1047R to breast cancer pathogenesis.</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21498569"> <div itemprop="name">Autophagy-deficient mice develop multiple liver tumors.</div> </a> <div itemprop="about">Genes & development</div> <div itemprop="author">Takamura A,Komatsu M,Hara T,Sakamoto A,Kishi C,Waguri S,Eishi Y,Hino O,Tanaka K,Mizushima N</div> <div itemprop="description">MA5-14520 was used in western blot to study the development of liver tumors in autophagy-deficient mice</div> <div itemprodp="datePublished">Fri Apr 15 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21852537"> <div itemprop="name">Validation of MdmX as a therapeutic target for reactivating p53 in tumors.</div> </a> <div itemprop="about">Genes & development</div> <div itemprop="author">Garcia D,Warr MR,Martins CP,Brown Swigart L,Passegué E,Evan GI</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study MdmX as a therapeutic target for reactivating p53 in tumors</div> <div itemprodp="datePublished">Mon Aug 15 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21478273"> <div itemprop="name">Endogenous Myc maintains the tumor microenvironment.</div> </a> <div itemprop="about">Genes & development</div> <div itemprop="author">Sodir NM,Swigart LB,Karnezis AN,Hanahan D,Evan GI,Soucek L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the involvement of endogenous Myc in tumor microenvironment maintenance</div> <div itemprodp="datePublished">Sun May 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21321570"> <div itemprop="name">Laser microdissection for the assessment of the clonal relationship between chronic lymphocytic leukemia/small lymphocytic lymphoma and proliferating B cells within lymph node pseudofollicles.</div> </a> <div itemprop="about">Leukemia</div> <div itemprop="author">Vandewoestyne ML,Pede VC,Lambein KY,Dhaenens MF,Offner FC,Praet MM,Philippé JJ,Kipps TJ,Deforce DL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate the laser microdissection technique for assessing the clonal relationship in chronic lymphocytic leukemia/small lymphocytic lymphoma</div> <div itemprodp="datePublished">Sun May 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21233172"> <div itemprop="name">Quantitative assessment of hepatic function during liver regeneration in a standardized rat model.</div> </a> <div itemprop="about">Journal of nuclear medicine : official publication, Society of Nuclear Medicine</div> <div itemprop="author">de Graaf W,Bennink RJ,Heger M,Maas A,de Bruin K,van Gulik TM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to compare different methods for assessing hepatic function during liver regeneration in a rat partial hepatectomy model</div> <div itemprodp="datePublished">Tue Feb 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21486690"> <div itemprop="name">Gastrointestinal stromal tumours in children and young adults: a clinicopathologic series with long-term follow-up from the database of the Cooperative Weichteilsarkom Studiengruppe (CWS).</div> </a> <div itemprop="about">European journal of cancer (Oxford, England : 1990)</div> <div itemprop="author">Benesch M,Leuschner I,Wardelmann E,Thielen M,Schmid I,Kontny U,Ebetsberger G,Frey E,Graf N,Schneider DT,Kremens B,Amann G,Urban C,Schlemmer M,Quehenberger F,Klingebiel T,Dantonello T,Koscielniak E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate gastrointestinal stromal tumours in patients with long-term follow-up</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21341272"> <div itemprop="name">Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models.</div> </a> <div itemprop="about">The Journal of pathology</div> <div itemprop="author">Navis AC,Hamans BC,Claes A,Heerschap A,Jeuken JW,Wesseling P,Leenders WP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of VEGF and PDGF pathway in glioma development</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21458915"> <div itemprop="name">Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer.</div> </a> <div itemprop="about">Cancer letters</div> <div itemprop="author">Barok M,Tanner M,Köninki K,Isola J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the efficacy of Trastuzumab-DM1 for the treatment of gastric cancer expressing HER2</div> <div itemprodp="datePublished">Thu Jul 28 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21407223"> <div itemprop="name">Inhibition of angiogenic and non-angiogenic targets by sorafenib in renal cell carcinoma (RCC) in a RCC xenograft model.</div> </a> <div itemprop="about">British journal of cancer</div> <div itemprop="author">Yuen JS,Sim MY,Siml HG,Chong TW,Lau WK,Cheng CW,Huynh H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the molecular targets of sorafenib in a xenograft model of renal cell carcinoma</div> <div itemprodp="datePublished">Tue Mar 15 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21423202"> <div itemprop="name">Blockade of the NFκB pathway drives differentiating glioblastoma-initiating cells into senescence both in vitro and in vivo.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Nogueira L,Ruiz-Ontañon P,Vazquez-Barquero A,Lafarga M,Berciano MT,Aldaz B,Grande L,Casafont I,Segura V,Robles EF,Suarez D,Garcia LF,Martinez-Climent JA,Fernandez-Luna JL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of NF-kappaB signal in the survival and development of glioblastoma-initiating cells</div> <div itemprodp="datePublished">Thu Aug 11 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21472018"> <div itemprop="name">Resistance or sensitivity of Wilms' tumor to anti-FZD7 antibody highlights the Wnt pathway as a possible therapeutic target.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Pode-Shakked N,Harari-Steinberg O,Haberman-Ziv Y,Rom-Gross E,Bahar S,Omer D,Metsuyanim S,Buzhor E,Jacob-Hirsch J,Goldstein RS,Mark-Danieli M,Dekel B</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to investigate the therapeutic value of FZD7 in Wilms tumor</div> <div itemprodp="datePublished">Thu Apr 07 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21150925"> <div itemprop="name">Development of skin-humanized mouse models of pachyonychia congenita.</div> </a> <div itemprop="about">The Journal of investigative dermatology</div> <div itemprop="author">García M,Larcher F,Hickerson RP,Baselga E,Leachman SA,Kaspar RL,Del Rio M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop and evaluate a mouse model for pachyonychia congenita</div> <div itemprodp="datePublished">Sun May 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21480209"> <div itemprop="name">Endothelium-coated tumor clusters are associated with poor prognosis and micrometastasis of hepatocellular carcinoma after resection.</div> </a> <div itemprop="about">Cancer</div> <div itemprop="author">Ding T,Xu J,Zhang Y,Guo RP,Wu WC,Zhang SD,Qian CN,Zheng L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the relationship between endothelium-coated tumor clusters and severity of liver cancer patients</div> <div itemprodp="datePublished">Tue Nov 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21308771"> <div itemprop="name">The orally bioavailable met inhibitor PF-2341066 inhibits osteosarcoma growth and osteolysis/matrix production in a xenograft model.</div> </a> <div itemprop="about">Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research</div> <div itemprop="author">Sampson ER,Martin BA,Morris AE,Xie C,Schwarz EM,O'Keefe RJ,Rosier RN</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of a selective Met inhibitor to attenuate osteosarcoma growth</div> <div itemprodp="datePublished">Wed Jun 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20921015"> <div itemprop="name">Optic nerve gliomas: role of Ki-67 staining of tumour and margins in predicting long-term outcome.</div> </a> <div itemprop="about">The British journal of ophthalmology</div> <div itemprop="author">Yeung SN,White VA,Nimmo M,Rootman J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the distribution of Ki-67 in optic nerve gliomas</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21221514"> <div itemprop="name">High frequency of development of B cell lymphoproliferation and diffuse large B cell lymphoma in Dbl knock-in mice.</div> </a> <div itemprop="about">Journal of molecular medicine (Berlin, Germany)</div> <div itemprop="author">Ognibene M,Barbieri O,Vanni C,Mastracci L,Astigiano S,Emionite L,Salani B,Fedele M,Resaz R,Tenca C,Fais F,Sabatini F,De Santanna A,Altruda F,Varesio L,Hirsch E,Eva A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of Dbl in the development of B cell lymphoma in mice</div> <div itemprodp="datePublished">Sun May 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21709667"> <div itemprop="name">Elf3 plays a role in regulating bronchiolar epithelial repair kinetics following Clara cell-specific injury.</div> </a> <div itemprop="about">Laboratory investigation; a journal of technical methods and pathology</div> <div itemprop="author">Oliver JR,Kushwah R,Wu J,Pan J,Cutz E,Yeger H,Waddell TK,Hu J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Elf3 in the repair of airway epithelium following injury</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21221032"> <div itemprop="name">Cyclooxygenase-2 supports tumor proliferation in vestibular schwannomas.</div> </a> <div itemprop="about">Neurosurgery</div> <div itemprop="author">Hong B,Krusche CA,Schwabe K,Friedrich S,Klein R,Krauss JK,Nakamura M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of cyclooxygenase-2 in tumor proliferation in vestibular Schwannomas</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21697348"> <div itemprop="name">Restrictions that control herpes simplex virus type 1 infection in mouse brain ex vivo.</div> </a> <div itemprop="about">The Journal of general virology</div> <div itemprop="author">Cohen M,Braun E,Tsalenchuck Y,Panet A,Steiner I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate tissue factors controlling HSV-1 infection in mouse brain slice culture</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20980348"> <div itemprop="name">Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation.</div> </a> <div itemprop="about">Carcinogenesis</div> <div itemprop="author">Hur K,Niwa T,Toyoda T,Tsukamoto T,Tatematsu M,Yang HK,Ushijima T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of persistent inflammation and cell proliferation in aberrant DNA methylation</div> <div itemprodp="datePublished">Sat Jan 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21732988"> <div itemprop="name">Influence of heparan sulfate chains in proteoglycan at the dermal-epidermal junction on epidermal homeostasis.</div> </a> <div itemprop="about">Experimental dermatology</div> <div itemprop="author">Iriyama S,Hiruma T,Tsunenaga M,Amano S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the functional properties of heparan sulfate chains at the dermal-epidermal junction</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21410765"> <div itemprop="name">Infrared radiation does not enhance the frequency of ultraviolet radiation-induced skin tumors, but their growth behaviour in mice.</div> </a> <div itemprop="about">Experimental dermatology</div> <div itemprop="author">Jantschitsch C,Weichenthal M,Maeda A,Proksch E,Schwarz T,Schwarz A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of infrared radiation on skin tumor induction and growth</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21045237"> <div itemprop="name">CDKN1B/p27 expression in peripheral T cell lymphoma not otherwise specified.</div> </a> <div itemprop="about">Journal of clinical pathology</div> <div itemprop="author">Gazzola A,Sista MT,Agostinelli C,Righi S,Sapienza MR,Mannu C,Rossi M,Bacci F,Sabattini E,Went P,Zinzani PL,Pileri SA,Piccaluga PP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study whether peripheral T-cell lymphoma involves aberrations of CDKN1B/p27</div> <div itemprodp="datePublished">Sat Jan 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21097789"> <div itemprop="name">Analysis of the IgVH genes in T cell-mediated and antibody-mediated rejection of the kidney graft.</div> </a> <div itemprop="about">Journal of clinical pathology</div> <div itemprop="author">Bellan C,Amato T,Carmellini M,Onorati M,D'Amuri A,Leoncini L,del Vecchio MT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of IgVH genes in host-graft rejection in renal transplants</div> <div itemprodp="datePublished">Sat Jan 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21488085"> <div itemprop="name">Spatial and temporal changes in promoter activity of the astrocyte glutamate transporter GLT1 following traumatic spinal cord injury.</div> </a> <div itemprop="about">Journal of neuroscience research</div> <div itemprop="author">Lepore AC,O'Donnell J,Bonner JF,Paul C,Miller ME,Rauck B,Kushner RA,Rothstein JD,Fischer I,Maragakis NJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the changes of astrocyte glutamate transporter GLT1 promoter activity after traumatic spinal cord injury</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21909647"> <div itemprop="name">The relationship among PDX1, CDX2, and mucin profiles in gastric carcinomas; correlations with clinicopathologic parameters.</div> </a> <div itemprop="about">Journal of cancer research and clinical oncology</div> <div itemprop="author">Oz Puyan F,Can N,Ozyilmaz F,Usta U,Sut N,Tastekin E,Altaner S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the association of PDX1 expression with various clinicopathologic parameters in gastric carcinomas</div> <div itemprodp="datePublished">Thu Dec 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21542667"> <div itemprop="name">Kidney spheroids recapitulate tubular organoids leading to enhanced tubulogenic potency of human kidney-derived cells.</div> </a> <div itemprop="about">Tissue engineering. Part A</div> <div itemprop="author">Buzhor E,Harari-Steinberg O,Omer D,Metsuyanim S,Jacob-Hirsch J,Noiman T,Dotan Z,Goldstein RS,Dekel B</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the strategy to maintain and control human renal cell growth and differentiation</div> <div itemprodp="datePublished">Thu Sep 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21031437"> <div itemprop="name">Topographical analysis of telomere length and correlation with genomic instability in whole mount prostatectomies.</div> </a> <div itemprop="about">The Prostate</div> <div itemprop="author">Joshua AM,Shen E,Yoshimoto M,Marrano P,Zielenska M,Evans AJ,Van der Kwast T,Squire JA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the association between telomere length and prostatic carcinogenesis</div> <div itemprodp="datePublished">Sun May 15 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21450330"> <div itemprop="name">Molecular phenotypes of matched in situ and invasive components of breast carcinomas.</div> </a> <div itemprop="about">Human pathology</div> <div itemprop="author">Martins D,Sousa B,Lopes N,Gomes M,Veronese L,Albergaria A,Paredes J,Schmitt F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to compare the tissue microarray immunoprofiles of in situ and invasive breast carcinoma components within the same sample</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21623205"> <div itemprop="name">Usefulness of p16ink4a, ProEX C, and Ki-67 for the diagnosis of glandular dysplasia and adenocarcinoma of the cervix uteri.</div> </a> <div itemprop="about">International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists</div> <div itemprop="author">Negri G,Bellisano G,Carico E,Faa G,Kasal A,Antoniazzi S,Egarter-Vigl E,Piccin A,Dalla Palma P,Vittadello F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate p16ink4a, ProEX C, and Ki-67 as biomarkers for glandular dysplasia and adenocarcinoma of the cervix uteri</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21643932"> <div itemprop="name">Cytogenetic analysis of a malignant triton tumour by comparative genomic hybridization (CGH) and review of the literature.</div> </a> <div itemprop="about">European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery</div> <div itemprop="author">Koutsimpelas D,Brieger J,Heinrich U,Torzewski M,Sommer C,Mann WJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to conduct comparative genomic hybridization analysis of malignant triton tumour</div> <div itemprodp="datePublished">Thu Sep 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21557987"> <div itemprop="name">X-irradiation reduces the proliferation of astrocytes by cell cycle arrest.</div> </a> <div itemprop="about">Neuroscience letters</div> <div itemprop="author">Wang Q,Xu Y,Xie MJ,Yu ZY,Qin YY,Wang W,Zhu Z</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the mechanism by which X-ray irradiation attenuates the proliferation of astrocytes</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21044186"> <div itemprop="name">Tumour eosinophilia combined with an immunohistochemistry panel is useful in the differentiation of type B3 thymoma from thymic carcinoma.</div> </a> <div itemprop="about">International journal of experimental pathology</div> <div itemprop="author">Khoury T,Chandrasekhar R,Wilding G,Tan D,Cheney RT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate an immunohistochemistry method to distinguish type B3 thymoma from thymic carcinoma</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21982272"> <div itemprop="name">Ki-67 and minichromosome maintenance-7 (MCM7) expression in canine pituitary corticotroph adenomas.</div> </a> <div itemprop="about">Domestic animal endocrinology</div> <div itemprop="author">Ishino H,Hara Y,Takekoshi S,Teshima T,Teramoto A,Osamura RY,Tagawa M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the expression of Ki-67 and MCM7 in canine pituitary corticotroph adenomas</div> <div itemprodp="datePublished">Tue Nov 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21153652"> <div itemprop="name">Investigation of galectin-3 and heparanase in endometrioid and serous carcinomas of the endometrium and correlation with known predictors of survival.</div> </a> <div itemprop="about">Archives of gynecology and obstetrics</div> <div itemprop="author">Ege CB,Akbulut M,Zekioğlu O,Ozdemir N</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of galectin-3 and heparanase on the pathogenesis of endometrial carcinomas</div> <div itemprodp="datePublished">Tue Nov 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21366719"> <div itemprop="name">Ectopic endometrial tissue in mesonephric duct remnants in bitches.</div> </a> <div itemprop="about">Reproduction in domestic animals = Zuchthygiene</div> <div itemprop="author">Bartel C,Berghold P,Walter I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study canine mesonephric remnants by immunohistochemistry</div> <div itemprodp="datePublished">Thu Dec 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20444729"> <div itemprop="name">Lymphoepithelioma-like carcinoma of the ovary.</div> </a> <div itemprop="about">International journal of surgical pathology</div> <div itemprop="author">Ambrosio MR,Rocca BJ,Onorati M,Mourmouras V,Mastrogiulio MG,Crispino S,Liberatore C,Santopietro R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of lymphoepithelioma-like carcinoma of the ovary</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19017661"> <div itemprop="name">Osteosarcoma arising in a long-standing uterine leiomyoma: a case report and literature review.</div> </a> <div itemprop="about">International journal of surgical pathology</div> <div itemprop="author">Wang RC,Wen MC,Wang J,Ho SC,Jan YJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of osteosarcoma occurring in a long-standing uterine leiomyoma</div> <div itemprodp="datePublished">Tue Feb 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21216781"> <div itemprop="name">Tumor-in-tumor of the thyroid with basaloid differentiation: a lesion with a solid cell nest neoplastic component?</div> </a> <div itemprop="about">International journal of surgical pathology</div> <div itemprop="author">Eloy C,Vinagre J,Cameselle-Teijeiro J,Paiva ME,Soares P,Sobrinho-Simões M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of tumor-in-tumor of the thyroid with basaloid differentiation</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20726867"> <div itemprop="name">Increased diagnostic accuracy of atypical glandular cells in cervical liquid-based cytology using cell blocks.</div> </a> <div itemprop="about">Cytopathology : official journal of the British Society for Clinical Cytology</div> <div itemprop="author">Risse EK,Holierhoek JP,Meijer-Marres EM,Ouwerkerk-Noordam E,Boon ME</div> <div itemprop="description">MA5-14520 was used in blocking or activating experiment to investigate the cell block experiment for the accurate diagnoses of atypical glandular cells</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20979437"> <div itemprop="name">Recurrence of benign meningiomas: predictive value of proliferative index, BCL2, p53, hormonal receptors and HER2 expression.</div> </a> <div itemprop="about">British journal of neurosurgery</div> <div itemprop="author">Abdelzaher E,El-Gendi SM,Yehya A,Gowil AG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to identify biomarkers that predict the recurrence of benign meningiomas</div> <div itemprodp="datePublished">Thu Dec 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21407201"> <div itemprop="name">Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis.</div> </a> <div itemprop="about">Nature communications</div> <div itemprop="author">Li S,Thangapazham RL,Wang JA,Rajesh S,Kao TC,Sperling L,Moss J,Darling TN</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of tuberous sclerosis complex in hair follicle formation and tissue regeneration</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21998733"> <div itemprop="name">Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Lepore AC,O'Donnell J,Kim AS,Williams T,Tuteja A,Rao MS,Kelley LL,Campanelli JT,Maragakis NJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the transplantation of human glial-restricted progenitors into the cervical spinal cord in a murine model of amyotrophic lateral sclerosis</div> <div itemprodp="datePublished">Mon Feb 13 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21561997"> <div itemprop="name">Enhancement of in vitro human tubulogenesis by endothelial cell-derived factors: implications for in vivo tubular regeneration after injury.</div> </a> <div itemprop="about">American journal of physiology. Renal physiology</div> <div itemprop="author">Miya M,Maeshima A,Mishima K,Sakurai N,Ikeuchi H,Kuroiwa T,Hiromura K,Yokoo H,Nojima Y</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of endothelial cell-derived proteins on human tubulogenesis and the significance for post-injury regeneration</div> <div itemprodp="datePublished">Mon Aug 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22235379"> <div itemprop="name">Tumor Vascular Morphology Undergoes Dramatic Changes during Outgrowth of B16 Melanoma While Proangiogenic Gene Expression Remains Unchanged.</div> </a> <div itemprop="about">ISRN oncology</div> <div itemprop="author">Langenkamp E,Vom Hagen FM,Zwiers PJ,Moorlag HE,Schouten JP,Hammes HP,Gouw AS,Molema G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the angiogenesis during the progression of tumor growth</div> <div itemprodp="datePublished">Thu Aug 23 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21703011"> <div itemprop="name">Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation.</div> </a> <div itemprop="about">BMC cancer</div> <div itemprop="author">Ager EI,Wen SW,Chan J,Chong WW,Neo JH,Christophi C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to test if targeting the classical and alternative arms of the renin angiotensin system inhibits colorectal cancer liver metastases</div> <div itemprodp="datePublished">Sun Jun 26 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22129892"> <div itemprop="name">Heat shock attenuates VEGF expression in three-dimensional myoblast sheets deteriorating therapeutic efficacy in heart failure.</div> </a> <div itemprop="about">Medical science monitor : international medical journal of experimental and clinical research</div> <div itemprop="author">Augustin M,Ali Asim Mahar M,Lakkisto P,Tikkanen I,Vento A,Patila T,Harjula A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry - paraffin section to test if heat shock pre-treatment affects the angiogenic properties of myoblast sheets in vivo and in vitro</div> <div itemprodp="datePublished">Thu Dec 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/22269404"> <div itemprop="name">Expression of fascin protein and mRNA in the KB carcinoma cell line following treatment with doxorubicin.</div> </a> <div itemprop="about">Journal of cancer research and therapeutics</div> <div itemprop="author">Alaeddini M,Fouladdel S,Etemad-Moghadam S,Azizi E</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the effect of doxorubicin on fascin protein and mRNA expression in the KB carcinoma cell line</div> <div itemprodp="datePublished">Tue Mar 20 00:00:00 EDT 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21215666"> <div itemprop="name">A comparative immunohistochemical analysis of COX-2, p53, and Ki-67 expression in keratocystic odontogenic tumors.</div> </a> <div itemprop="about">Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics</div> <div itemprop="author">Mendes RA,Carvalho JF,van der Waal I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the expression of cyclooxygenase-2, p53 and Ki-67 in keratocystic odontogenic tumors</div> <div itemprodp="datePublished">Tue Mar 01 00:00:00 EST 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21305519"> <div itemprop="name">Inhibition of the catalytic function of activation-induced cytidine deaminase promotes apoptosis of germinal center B cells in BXD2 mice.</div> </a> <div itemprop="about">Arthritis and rheumatism</div> <div itemprop="author">Hsu HC,Yang P,Wu Q,Wang JH,Job G,Guentert T,Li J,Stockard CR,Le TV,Chaplin DD,Grizzle WE,Mountz JD</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to determine if loss of activation-induced cytidine deaminase catalytic activity can suppress hyper-reactive germinal centre responses.</div> <div itemprodp="datePublished">Fri Jul 01 00:00:00 EDT 2011</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20393564"> <div itemprop="name">Therapeutic antibody targeting of individual Notch receptors.</div> </a> <div itemprop="about">Nature</div> <div itemprop="author">Wu Y,Cain-Hom C,Choy L,Hagenbeek TJ,de Leon GP,Chen Y,Finkle D,Venook R,Wu X,Ridgway J,Schahin-Reed D,Dow GJ,Shelton A,Stawicki S,Watts RJ,Zhang J,Choy R,Howard P,Kadyk L,Yan M,Zha J,Callahan CA,Hymowitz SG,Siebel CW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study therapeutic antibody targeting of individual Notch receptors</div> <div itemprodp="datePublished">Thu Apr 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20194817"> <div itemprop="name">Thyroid transcription factor-1 influences the early phase of compensatory lung growth in adult mice.</div> </a> <div itemprop="about">American journal of respiratory and critical care medicine</div> <div itemprop="author">Takahashi Y,Izumi Y,Kohno M,Kimura T,Kawamura M,Okada Y,Nomori H,Ikeda E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of thyroid transcription factor-1 in lung development</div> <div itemprodp="datePublished">Tue Jun 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20439541"> <div itemprop="name">The fusion kinase ITK-SYK mimics a T cell receptor signal and drives oncogenesis in conditional mouse models of peripheral T cell lymphoma.</div> </a> <div itemprop="about">The Journal of experimental medicine</div> <div itemprop="author">Pechloff K,Holch J,Ferch U,Schweneker M,Brunner K,Kremer M,Sparwasser T,Quintanilla-Martinez L,Zimber-Strobl U,Streubel B,Gewies A,Peschel C,Ruland J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of the fusion ITK-SYK kinase in oncogenesis</div> <div itemprodp="datePublished">Mon May 10 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20829331"> <div itemprop="name">PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Zhang CC,Yan Z,Zhang Q,Kuszpit K,Zasadny K,Qiu M,Painter CL,Wong A,Kraynov E,Arango ME,Mehta PP,Popoff I,Casperson GF,Los G,Bender S,Anderes K,Christensen JG,VanArsdale T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the biological properties of an anti-P-cadherin human monoclonal antibody in cell assays and in multiple tumor models</div> <div itemprodp="datePublished">Mon Nov 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20215547"> <div itemprop="name">PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Bartholomeusz C,Gonzalez-Angulo AM,Kazansky A,Krishnamurthy S,Liu P,Yuan LX,Yamasaki F,Liu S,Hayashi N,Zhang D,Esteva FJ,Hortobagyi GN,Ueno NT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which PEA-15 inhibits tumorigenesis in a xenograft model of triple-negative breast cancer</div> <div itemprodp="datePublished">Mon Mar 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20807818"> <div itemprop="name">Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Mellick AS,Plummer PN,Nolan DJ,Gao D,Bambino K,Hahn M,Catena R,Turner V,McDonnell K,Benezra R,Brink R,Swarbrick A,Mittal V</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop a system to selectively target endothelial progenitor cells as a novel strategy to inhibit tumor angiogenesis and growth</div> <div itemprodp="datePublished">Wed Sep 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20197467"> <div itemprop="name">Downregulation of Notch pathway by a gamma-secretase inhibitor attenuates AKT/mammalian target of rapamycin signaling and glucose uptake in an ERBB2 transgenic breast cancer model.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Efferson CL,Winkelmann CT,Ware C,Sullivan T,Giampaoli S,Tammam J,Patel S,Mesiti G,Reilly JF,Gibson RE,Buser C,Yeatman T,Coppola D,Winter C,Clark EA,Draetta GF,Strack PR,Majumder PK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of gamma-secretase inhibition of the Notch pathway on AKT/mTor signaling and glucose uptake in a murine ERBB2 breast cancer model</div> <div itemprodp="datePublished">Mon Mar 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20439741"> <div itemprop="name">Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth.</div> </a> <div itemprop="about">Proceedings of the National Academy of Sciences of the United States of America</div> <div itemprop="author">Murray BW,Guo C,Piraino J,Westwick JK,Zhang C,Lamerdin J,Dagostino E,Knighton D,Loi CM,Zager M,Kraynov E,Popoff I,Christensen JG,Martinez R,Kephart SE,Marakovits J,Karlicek S,Bergqvist S,Smeal T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study anti-tumor activity and mechanism of a novel small molecule PAK4 inhibitor in vitro and against a number of human cancer xenograft models</div> <div itemprodp="datePublished">Tue May 18 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20484105"> <div itemprop="name">Effect of the secretory small GTPase Rab27B on breast cancer growth, invasion, and metastasis.</div> </a> <div itemprop="about">Journal of the National Cancer Institute</div> <div itemprop="author">Hendrix A,Maynard D,Pauwels P,Braems G,Denys H,Van den Broecke R,Lambert J,Van Belle S,Cocquyt V,Gespach C,Bracke M,Seabra MC,Gahl WA,De Wever O,Westbroek W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of secretory small GTPase Rab27B in breast cancer proliferation and metastasis</div> <div itemprodp="datePublished">Wed Jun 16 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20956472"> <div itemprop="name">111In-bevacizumab imaging of renal cell cancer and evaluation of neoadjuvant treatment with the vascular endothelial growth factor receptor inhibitor sorafenib.</div> </a> <div itemprop="about">Journal of nuclear medicine : official publication, Society of Nuclear Medicine</div> <div itemprop="author">Desar IM,Stillebroer AB,Oosterwijk E,Leenders WP,van Herpen CM,van der Graaf WT,Boerman OC,Mulders PF,Oyen WJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the use of (111)Ln bavacizumab to evaluate the response to treatment with aVEGF receptor inhibitor in renal cell cancer.</div> <div itemprodp="datePublished">Mon Nov 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20221685"> <div itemprop="name">VHL and PTEN loss coordinate to promote mouse liver vascular lesions.</div> </a> <div itemprop="about">Angiogenesis</div> <div itemprop="author">Chen S,Sanford CA,Sun J,Choi V,Van Dyke T,Samulski RJ,Rathmell WK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of PTEN/VHL deletion in the development of liver vascular lesions</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20847306"> <div itemprop="name">Indirubin-3'-monoxime blocks vascular smooth muscle cell proliferation by inhibition of signal transducer and activator of transcription 3 signaling and reduces neointima formation in vivo.</div> </a> <div itemprop="about">Arteriosclerosis, thrombosis, and vascular biology</div> <div itemprop="author">Schwaiberger AV,Heiss EH,Cabaravdic M,Oberan T,Zaujec J,Schachner D,Uhrin P,Atanasov AG,Breuss JM,Binder BR,Dirsch VM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of indirubin-3-monoxime on vascular smooth muscle cell proliferation and neointima formation</div> <div itemprodp="datePublished">Wed Dec 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20501936"> <div itemprop="name">The balance of WNT and FGF signaling influences mesenchymal stem cell fate during skeletal development.</div> </a> <div itemprop="about">Science signaling</div> <div itemprop="author">Maruyama T,Mirando AJ,Deng CX,Hsu W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of WNT and FGF signaling on mesenchymal stem cell differentiation</div> <div itemprodp="datePublished">Tue May 25 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20354524"> <div itemprop="name">Oncogenic KRAS sensitises colorectal tumour cells to chemotherapy by p53-dependent induction of Noxa.</div> </a> <div itemprop="about">British journal of cancer</div> <div itemprop="author">de Bruijn MT,Raats DA,Hoogwater FJ,van Houdt WJ,Cameron K,Medema JP,Borel Rinkes IH,Kranenburg O</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of KRAS on the cellular response to chemotherapy and its mechanism</div> <div itemprodp="datePublished">Tue Apr 13 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20101233"> <div itemprop="name">Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Andrieu C,Taieb D,Baylot V,Ettinger S,Soubeyran P,De-Thonel A,Nelson C,Garrido C,So A,Fazli L,Bladou F,Gleave M,Iovanna JL,Rocchi P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study anti-apoptotic pathways during prostate cancer progression</div> <div itemprodp="datePublished">Thu Apr 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19908231"> <div itemprop="name">Resveratrol, a multitargeted agent, can enhance antitumor activity of gemcitabine in vitro and in orthotopic mouse model of human pancreatic cancer.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Harikumar KB,Kunnumakkara AB,Sethi G,Diagaradjane P,Anand P,Pandey MK,Gelovani J,Krishnan S,Guha S,Aggarwal BB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the ability of resveratrol to enhance the antitumor activity of gemcitabine against pancreatic cancer cell lines and a xenograpft model of human pancreatic cancer</div> <div itemprodp="datePublished">Thu Jul 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19642098"> <div itemprop="name">Extraribosomal function of metallopanstimulin-1: reducing paxillin in head and neck squamous cell carcinoma and inhibiting tumor growth.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Dai Y,Pierson SE,Dudney WC,Stack BC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of metallopanstimulin-1 on tumor growth and gene expression</div> <div itemprodp="datePublished">Mon Feb 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20592198"> <div itemprop="name">Early pharmacotherapy restores neurogenesis and cognitive performance in the Ts65Dn mouse model for Down syndrome.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Bianchi P,Ciani E,Guidi S,Trazzi S,Felice D,Grossi G,Fernandez M,Giuliani A,Calzà L,Bartesaghi R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study whether early pharmacotherapy corrects neurogenesis and cognitive function in a mouse model of Downs syndrome.</div> <div itemprodp="datePublished">Wed Jun 30 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20147530"> <div itemprop="name">Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Gao Y,Vasilyev DV,Goncalves MB,Howell FV,Hobbs C,Reisenberg M,Shen R,Zhang MY,Strassle BW,Lu P,Mark L,Piesla MJ,Deng K,Kouranova EV,Ring RH,Whiteside GT,Bates B,Walsh FS,Williams G,Pangalos MN,Samad TA,Doherty P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of DAGLalpha on retrograde synaptic plasticity and adult neurogenesis</div> <div itemprodp="datePublished">Wed Feb 10 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20685991"> <div itemprop="name">Notch1 is required for maintenance of the reservoir of adult hippocampal stem cells.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Ables JL,Decarolis NA,Johnson MA,Rivera PD,Gao Z,Cooper DC,Radtke F,Hsieh J,Eisch AJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Notch1 in maintaining a reservoir of adult hippocampal stem cells</div> <div itemprodp="datePublished">Wed Aug 04 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20637733"> <div itemprop="name">Antiangiogenic effect of licochalcone A.</div> </a> <div itemprop="about">Biochemical pharmacology</div> <div itemprop="author">Kim YH,Shin EK,Kim DH,Lee HH,Park JH,Kim JK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study whether licochalcone A is able to inhibit angiogenesis</div> <div itemprodp="datePublished">Fri Oct 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20442301"> <div itemprop="name">A novel small-molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Harikumar KB,Kunnumakkara AB,Ochi N,Tong Z,Deorukhkar A,Sung B,Kelland L,Jamieson S,Sutherland R,Raynham T,Charles M,Bagherzadeh A,Foxton C,Boakes A,Farooq M,Maru D,Diagaradjane P,Matsuo Y,Sinnett-Smith J,Gelovani J,Krishnan S,Aggarwal BB,Rozengurt E,Ireson CR,Guha S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the inhibition of pancreatic cancer growth by a novel small molecule protein kinase D inhibitor</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20299606"> <div itemprop="name">The endothelial mineralocorticoid receptor regulates vasoconstrictor tone and blood pressure.</div> </a> <div itemprop="about">FASEB journal : official publication of the Federation of American Societies for Experimental Biology</div> <div itemprop="author">Nguyen Dinh Cat A,Griol-Charhbili V,Loufrani L,Labat C,Benjamin L,Farman N,Lacolley P,Henrion D,Jaisser F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of endothelial mineralocorticoid receptor on vasoconstrictor tone and blood pressure</div> <div itemprodp="datePublished">Thu Jul 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20581057"> <div itemprop="name">S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Wang XH,Zhang LH,Zhong XY,Xing XF,Liu YQ,Niu ZJ,Peng Y,Du H,Zhang GG,Hu Y,Liu N,Zhu YB,Ge SH,Zhao W,Lu AP,Li JY,Ji JF</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the prognostic significance of S100A6 overexpression in gastric cancer</div> <div itemprodp="datePublished">Sun Aug 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20133812"> <div itemprop="name">Epithelial-stromal interaction 1 (EPSTI1) substitutes for peritumoral fibroblasts in the tumor microenvironment.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">de Neergaard M,Kim J,Villadsen R,Fridriksdottir AJ,Rank F,Timmermans-Wielenga V,Langerød A,Børresen-Dale AL,Petersen OW,Rønnov-Jessen L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of epithelial-stromal interaction-1 in human tumors</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20202079"> <div itemprop="name">Eph receptor tyrosine kinases regulate astrocyte cytoskeletal rearrangement and focal adhesion formation.</div> </a> <div itemprop="about">Journal of neurochemistry</div> <div itemprop="author">Puschmann TB,Turnley AM</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the role of EphA4 in regulating astrocyte cytoskeletal responses</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20889546"> <div itemprop="name">Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals.</div> </a> <div itemprop="about">Journal of immunology (Baltimore, Md. : 1950)</div> <div itemprop="author">Gordon SN,Cervasi B,Odorizzi P,Silverman R,Aberra F,Ginsberg G,Estes JD,Paiardini M,Frank I,Silvestri G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of intestinal CD4+ T cell homeostasis in HIV-infected individuals</div> <div itemprodp="datePublished">Mon Nov 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19835469"> <div itemprop="name">Heparanase expression of glioma in human and animal models.</div> </a> <div itemprop="about">Journal of neurosurgery</div> <div itemprop="author">Hong X,Nelson KK,deCarvalho AC,Kalkanis SN</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to characterize the expression of mammalian heparanase</div> <div itemprodp="datePublished">Sun Aug 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20399617"> <div itemprop="name">TGF-beta1 causes epithelial-mesenchymal transition in HaCaT derivatives, but induces expression of COX-2 and migration only in benign, not in malignant keratinocytes.</div> </a> <div itemprop="about">Journal of dermatological science</div> <div itemprop="author">Räsänen K,Vaheri A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Cox-2 in the TGF-beta1 mediated epithelial-mesenchymal transition response</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20620021"> <div itemprop="name">Immuno-histochemical evaluation of solar lentigines: The association of KGF/KGFR and other factors with lesion development.</div> </a> <div itemprop="about">Journal of dermatological science</div> <div itemprop="author">Lin CB,Hu Y,Rossetti D,Chen N,David C,Slominski A,Seiberg M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of KGF/KGF receptor and other pigmentary genes in the development of lesions in solar lentigines</div> <div itemprodp="datePublished">Sun Aug 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20025477"> <div itemprop="name">A class discovery and class prediction approach to histopathological classification of mammographic screen detected columnar cell lesions of the breast.</div> </a> <div itemprop="about">Pathology</div> <div itemprop="author">Pathmanathan N,Salisbury EL,Provan PJ,Bilous AM,Byth K,Milliken JS,Clarke CL,Balleine RL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate a novel method for the classification of breast columnar cell lesions</div> <div itemprodp="datePublished">Fri Jan 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20410256"> <div itemprop="name">Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase.</div> </a> <div itemprop="about">International immunology</div> <div itemprop="author">Stroo I,Stokman G,Teske GJ,Raven A,Butter LM,Florquin S,Leemans JC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the proliferation of tubular epithelial cells after renal ischemia/reperfusion injury</div> <div itemprodp="datePublished">Tue Jun 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20855524"> <div itemprop="name">Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark.</div> </a> <div itemprop="about">Molecular and cellular biology</div> <div itemprop="author">Revenko AS,Kalashnikova EV,Gemo AT,Zou JX,Chen HW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism of chromatin loading of the E2F-MLL complex by cancer-associated coregulator ANCCA</div> <div itemprodp="datePublished">Mon Nov 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19780816"> <div itemprop="name">The role of keratinocyte growth factor in melanogenesis: a possible mechanism for the initiation of solar lentigines.</div> </a> <div itemprop="about">Experimental dermatology</div> <div itemprop="author">Chen N,Hu Y,Li WH,Eisinger M,Seiberg M,Lin CB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of keratinocyte growth factor in melanogenesis and solar lentigines</div> <div itemprodp="datePublished">Fri Oct 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20069634"> <div itemprop="name">Diagnostic value of p16INK4A, Ki-67, and human papillomavirus L1 capsid protein immunochemical staining on cell blocks from residual liquid-based gynecologic cytology specimens.</div> </a> <div itemprop="about">Cancer cytopathology</div> <div itemprop="author">Yu L,Wang L,Zhong J,Chen S</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to evaluate a cell block preparation technique for cytologic diagnosis of residual liquid-based gynecologic specimens</div> <div itemprodp="datePublished">Thu Feb 25 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20097197"> <div itemprop="name">Proliferation and motility of HaCaT keratinocyte derivatives is enhanced by fibroblast nemosis.</div> </a> <div itemprop="about">Experimental cell research</div> <div itemprop="author">Räsänen K,Vaheri A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of fibroblast nemosis on the proliferation and motility of HaCaT keratinocyte derivatives and the significance for tumor progression</div> <div itemprodp="datePublished">Thu Jun 10 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20486792"> <div itemprop="name">Adipose tissue progenitor cells directly interact with endothelial cells to induce vascular network formation.</div> </a> <div itemprop="about">Tissue engineering. Part A</div> <div itemprop="author">Merfeld-Clauss S,Gollahalli N,March KL,Traktuev DO</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms by which the interaction of adipose tissue progenitor cells with endothelial cells promotes vasculogenesis</div> <div itemprodp="datePublished">Wed Sep 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19913282"> <div itemprop="name">Desmoplastic small round cell tumor of the submandibular gland--a rare but distinctive primary salivary gland neoplasm.</div> </a> <div itemprop="about">Human pathology</div> <div itemprop="author">Yin WH,Guo SP,Yang HY,Chan JK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of desmoplastic small round cell tumor of the submandibular gland</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20400234"> <div itemprop="name">The pathogenic role of Epstein-Barr virus (EBV) in sclerosing polycystic adenosis.</div> </a> <div itemprop="about">Pathology, research and practice</div> <div itemprop="author">Swelam WM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of EBV infection in the pathogenesis of sclerosing polycystic adenosis</div> <div itemprodp="datePublished">Sun Aug 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19854167"> <div itemprop="name">Cell cycle regulation in the inner ear sensory epithelia: role of cyclin D1 and cyclin-dependent kinase inhibitors.</div> </a> <div itemprop="about">Developmental biology</div> <div itemprop="author">Laine H,Sulg M,Kirjavainen A,Pirvola U</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of cyclin D1 in inner ear sensory epithelial cell cycle regulation</div> <div itemprodp="datePublished">Fri Jan 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20226438"> <div itemprop="name">What would be left behind if subtotal thyroidectomy were preferred instead of total thyroidectomy?</div> </a> <div itemprop="about">American journal of surgery</div> <div itemprop="author">Tekin K,Yilmaz S,Yalçin N,Coban S,Aydin C,Kabay B,Erdem E,Ozbaş S,Ozden A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the cellular proliferative activity of remnant thyroid tissues after subtotal thyroidectomy</div> <div itemprodp="datePublished">Tue Jun 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20336306"> <div itemprop="name">A comparison of Ki-67 antigen presentation in acute generalized exanthematous pustulosis and pustular psoriasis.</div> </a> <div itemprop="about">Archives of dermatological research</div> <div itemprop="author">Chang SL,Hu S,Hung SI,Huang YL,Hsiao WC,Chung WH</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to compare Ki-67 immunostaining in acute generalized exanthematous pustulosis and pustular psoriasis</div> <div itemprodp="datePublished">Wed Sep 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20570189"> <div itemprop="name">Evaluation of clinico-pathological criteria and the Ki67 index as prognostic indicators in canine insulinoma.</div> </a> <div itemprop="about">Veterinary journal (London, England : 1997)</div> <div itemprop="author">Buishand FO,Kik M,Kirpensteijn J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the prognostic significance of Ki67 in insulinoma</div> <div itemprodp="datePublished">Thu Jul 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20022446"> <div itemprop="name">Expression of Ki-67, PCNA, and p27kip1 in canine pituitary corticotroph adenomas.</div> </a> <div itemprop="about">Domestic animal endocrinology</div> <div itemprop="author">van Rijn SJ,Grinwis GC,Penning LC,Meij BP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the level of specific proliferative proteins in pituitary corticotroph adenomas</div> <div itemprodp="datePublished">Sat May 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20393007"> <div itemprop="name">Phellodendron amurense bark extract prevents progression of prostate tumors in transgenic adenocarcinoma of mouse prostate: potential for prostate cancer management.</div> </a> <div itemprop="about">Anticancer research</div> <div itemprop="author">Ghosh R,Graham H,Rivas P,Tan XJ,Crosby K,Bhaskaran S,Schoolfield J,Banu J,Fernandes G,Yeh IT,Kumar AP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of Phellodendron amurense bark extract on the progression of prostate tumors in a mouse model</div> <div itemprodp="datePublished">Mon Mar 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20133985"> <div itemprop="name">Synchronous presentation of GISTs and other primary neoplasms: a single center experience.</div> </a> <div itemprop="about">In vivo (Athens, Greece)</div> <div itemprop="author">Arnogiannaki N,Martzoukou I,Kountourakis P,Dimitriadis E,Papathanasaki A,Nastoulis E,Gazalidou M,Fida A,Apostolikas N,Agnantis NJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to perform immunohistochemical and mutational analysis of clinical cases of gastrointestinal stromal tumors</div> <div itemprodp="datePublished">Wed Apr 14 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20616378"> <div itemprop="name">Acute ANIT toxicity in male IL-10 knockout and wild-type mice.</div> </a> <div itemprop="about">Toxicologic pathology</div> <div itemprop="author">Faiola B,Peterson RA,Kimbrough CL,Jordan HL,Cullen JM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study acute alpha-napthylisothiocyanate toxicity in male IL-10 knockout and wild-type mice</div> <div itemprodp="datePublished">Sun Aug 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21331997"> <div itemprop="name">Evaluation of the presence of Helicobacter species in the biliary system of Turkish patients with cholelithiasis.</div> </a> <div itemprop="about">The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology</div> <div itemprop="author">Bostanoğlu E,Karahan ZC,Bostanoğlu A,Savaş B,Erden E,Kiyan M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate the presence of Helicobacter species in the biliary system of Turkish patients with cholelithiasis</div> <div itemprodp="datePublished">Wed Dec 01 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20140254"> <div itemprop="name">High-precision radiosurgical dose delivery by interlaced microbeam arrays of high-flux low-energy synchrotron X-rays.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Serduc R,Bräuer-Krisch E,Siegbahn EA,Bouchet A,Pouyatos B,Carron R,Pannetier N,Renaud L,Berruyer G,Nemoz C,Brochard T,Rémy C,Barbier EL,Bravin A,Le Duc G,Depaulis A,Estève F,Laissue JA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate interlaced microbeam arrays of high-flux low-energy synchrotron X-rays for radiosurgery</div> <div itemprodp="datePublished">Wed Feb 03 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20161711"> <div itemprop="name">DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Osada M,Jardine L,Misir R,Andl T,Millar SE,Pezzano M</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to investigate Wnt signaling effects on T cell development</div> <div itemprodp="datePublished">Mon Feb 08 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20549696"> <div itemprop="name">Methylnitrosourea induces neural progenitor cell apoptosis and microcephaly in mouse embryos.</div> </a> <div itemprop="about">Birth defects research. Part B, Developmental and reproductive toxicology</div> <div itemprop="author">Komada M,Fujiyama F,Yamada S,Shiota K,Nagao T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the pathogenic mechanisms of methylnitrosourea in developing mouse cerebral cortex</div> <div itemprodp="datePublished">Tue Jun 01 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21108812"> <div itemprop="name">Mutually exclusive expression of DLX2 and DLX5/6 is associated with the metastatic potential of the human breast cancer cell line MDA-MB-231.</div> </a> <div itemprop="about">BMC cancer</div> <div itemprop="author">Morini M,Astigiano S,Gitton Y,Emionite L,Mirisola V,Levi G,Barbieri O</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the association of mutually exclusive expression of DLX2 and DLX5/6 with metastatic potential in a human breast cancer cell line</div> <div itemprodp="datePublished">Thu Nov 25 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20559570"> <div itemprop="name">Etk/Bmx regulates proteinase-activated-receptor1 (PAR1) in breast cancer invasion: signaling partners, hierarchy and physiological significance.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Cohen I,Maoz M,Turm H,Grisaru-Granovsky S,Maly B,Uziely B,Weiss E,Abramovitch R,Gross E,Barzilay O,Qiu Y,Bar-Shavit R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the cellular signalling pathways involved in proteinase-activated receptor-1 (PAR-1) mediated breast cancer invasion.</div> <div itemprodp="datePublished">Tue Jun 15 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21067603"> <div itemprop="name">Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.</div> </a> <div itemprop="about">BMC developmental biology</div> <div itemprop="author">DeRouen MC,Zhen H,Tan SH,Williams S,Marinkovich MP,Oro AE</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to investigate the role of laminin-511 in hair follicle development</div> <div itemprodp="datePublished">Wed Nov 10 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20598147"> <div itemprop="name">Small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation: a case report.</div> </a> <div itemprop="about">Molecular cytogenetics</div> <div itemprop="author">Pacheco M,Horsman DE,Hayes MM,Clarkson PW,Huwait H,Nielsen TO</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of small blue round cell tumor of the interosseous membrane bearing a t(2;22)(q34;q12)/EWS-CREB1 translocation</div> <div itemprodp="datePublished">Fri Jul 02 00:00:00 EDT 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/21109727"> <div itemprop="name">Species differences in reactivity of mouse and rat astrocytes in vitro.</div> </a> <div itemprop="about">Neuro-Signals</div> <div itemprop="author">Puschmann TB,Dixon KJ,Turnley AM</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the different reactivities of mouse and rat astrocytes in vitro</div> <div itemprodp="datePublished">Thu Feb 09 00:00:00 EST 2012</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19671544"> <div itemprop="name">Gliadin-primed CD4+CD45RBlowCD25- T cells drive gluten-dependent small intestinal damage after adoptive transfer into lymphopenic mice.</div> </a> <div itemprop="about">Gut</div> <div itemprop="author">Freitag TL,Rietdijk S,Junker Y,Popov Y,Bhan AK,Kelly CP,Terhorst C,Schuppan D</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of gliadin-primed CD4+CD45RBlowCD25- T cells in gluten-induced enteropathy</div> <div itemprodp="datePublished">Tue Dec 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19179371"> <div itemprop="name">A rapid non-radioactive technique for measurement of repair synthesis in primary human fibroblasts by incorporation of ethynyl deoxyuridine (EdU).</div> </a> <div itemprop="about">Nucleic acids research</div> <div itemprop="author">Limsirichaikul S,Niimi A,Fawcett H,Lehmann A,Yamashita S,Ogi T</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to evaluate a novel method for DNA repair analysis</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19127517"> <div itemprop="name">Knockout of myeloid cell leukemia-1 induces liver damage and increases apoptosis susceptibility of murine hepatocytes.</div> </a> <div itemprop="about">Hepatology (Baltimore, Md.)</div> <div itemprop="author">Vick B,Weber A,Urbanik T,Maass T,Teufel A,Krammer PH,Opferman JT,Schuchmann M,Galle PR,Schulze-Bergkamen H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Mcl-1 in liver damage and apoptosis in hepatocytes from knockout mice</div> <div itemprodp="datePublished">Sun Feb 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19057917"> <div itemprop="name">Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.</div> </a> <div itemprop="about">Acta neuropathologica</div> <div itemprop="author">Pfister S,Remke M,Castoldi M,Bai AH,Muckenthaler MU,Kulozik A,von Deimling A,Pscherer A,Lichter P,Korshunov A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of pediatric embryonal tumor displaying novel genomic amplification targeting the microRNA cluster at 19q13.42</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19228735"> <div itemprop="name">Role of the microenvironment for radiosensitization by patupilone.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Bley CR,Jochum W,Orlowski K,Furmanova P,Vuong V,McSheehy PM,Pruschy M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the tumor microenvironment in radiosensitization by the microtubule-stabilizing compound patupilone</div> <div itemprodp="datePublished">Sun Feb 15 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19738074"> <div itemprop="name">Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Zhang W,Zhu J,Efferson CL,Ware C,Tammam J,Angagaw M,Laskey J,Bettano KA,Kasibhatla S,Reilly JF,Sur C,Majumder PK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the anti-tumor effect of anti-androgen and rapamycin treatment in a murine prostate cancer model</div> <div itemprodp="datePublished">Tue Sep 15 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19258510"> <div itemprop="name">Coordination of intratumoral immune reaction and human colorectal cancer recurrence.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Camus M,Tosolini M,Mlecnik B,Pagès F,Kirilovsky A,Berger A,Costes A,Bindea G,Charoentong P,Bruneval P,Trajanoski Z,Fridman WH,Galon J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the correlation of intratumoral immune markers and human colorectal cancer escape</div> <div itemprodp="datePublished">Sun Mar 15 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19487287"> <div itemprop="name">Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Gravdal K,Halvorsen OJ,Haukaas SA,Akslen LA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study proliferation of immature tumor vessels as a novel marker of clinical progression in prostate cancer</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18952695"> <div itemprop="name">Perivascular adipose tissue-derived visfatin is a vascular smooth muscle cell growth factor: role of nicotinamide mononucleotide.</div> </a> <div itemprop="about">Cardiovascular research</div> <div itemprop="author">Wang P,Xu TY,Guan YF,Su DF,Fan GR,Miao CY</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the role of perivascular adipose tissue-derived visfatin as a vascular smooth muscle cell growth factor</div> <div itemprodp="datePublished">Sun Feb 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19564597"> <div itemprop="name">Syncytin-A knockout mice demonstrate the critical role in placentation of a fusogenic, endogenous retrovirus-derived, envelope gene.</div> </a> <div itemprop="about">Proceedings of the National Academy of Sciences of the United States of America</div> <div itemprop="author">Dupressoir A,Vernochet C,Bawa O,Harper F,Pierron G,Opolon P,Heidmann T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of syncytin during placenta development in mice</div> <div itemprodp="datePublished">Tue Jul 21 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19318677"> <div itemprop="name">Apoptosis-related (survivin, Bcl-2), tumor suppressor gene (p53), proliferation (Ki-67), and non-receptor tyrosine kinase (Src) markers expression and correlation with clinicopathologic variables in 60 thymic neoplasms.</div> </a> <div itemprop="about">Chest</div> <div itemprop="author">Khoury T,Arshad A,Bogner P,Ramnath N,Zhang S,Chandrasekhar R,Wilding G,Alrawi S,Tan D</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the changes of specific genes in patients with thymic neoplasms</div> <div itemprodp="datePublished">Wed Jul 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19734041"> <div itemprop="name">Tumour control by whole brain irradiation of anti-VEGF-treated mice bearing intracerebral glioma.</div> </a> <div itemprop="about">European journal of cancer (Oxford, England : 1990)</div> <div itemprop="author">Verhoeff JJ,Stalpers LJ,Claes A,Hovinga KE,Musters GD,Peter Vandertop W,Richel DJ,Leenders WP,van Furth WR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to identify the efficacy of anti-VEGF treatment and irradiation to control brain tumour proliferation in mice.</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19775282"> <div itemprop="name">Down-regulation of the Notch pathway mediated by a gamma-secretase inhibitor induces anti-tumour effects in mouse models of T-cell leukaemia.</div> </a> <div itemprop="about">British journal of pharmacology</div> <div itemprop="author">Tammam J,Ware C,Efferson C,O'Neil J,Rao S,Qu X,Gorenstein J,Angagaw M,Kim H,Kenific C,Kunii K,Leach KJ,Nikov G,Zhao J,Dai X,Hardwick J,Scott M,Winter C,Bristow L,Elbi C,Reilly JF,Look T,Draetta G,Van der Ploeg L,Kohl NE,Strack PR,Majumder PK</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the anti-tumor effects of inhibiting Notch signaling with a gamma secretase inhibitor in a mouse T-cell leukaemia model</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19398955"> <div itemprop="name">Melanocytic nevus-like hyperplasia and melanoma in transgenic BRAFV600E mice.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Goel VK,Ibrahim N,Jiang G,Singhal M,Fee S,Flotte T,Westmoreland S,Haluska FS,Hinds PW,Haluska FG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the role of BRAFV600E mutation in the pathogenesis of melanocytic melanoma</div> <div itemprodp="datePublished">Thu Jun 11 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19614675"> <div itemprop="name">Gender differences in pulmonary regenerative response to naphthalene-induced bronchiolar epithelial cell injury.</div> </a> <div itemprop="about">Cell proliferation</div> <div itemprop="author">Oliver JR,Kushwah R,Wu J,Cutz E,Yeger H,Waddell TK,Hu J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study gender differences in lung repair responses to naphthalene-induced Clara cell ablation</div> <div itemprodp="datePublished">Thu Oct 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19490419"> <div itemprop="name">Cross-species immunohistochemical investigation of the activation of the liver progenitor cell niche in different types of liver disease.</div> </a> <div itemprop="about">Liver international : official journal of the International Association for the Study of the Liver</div> <div itemprop="author">Schotanus BA,van den Ingh TS,Penning LC,Rothuizen J,Roskams TA,Spee B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the activation of liver progenitor cell niche in various liver diseases</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19912365"> <div itemprop="name">Vessel density assessed by endoglin expression in breast carcinomas with different expression profiles.</div> </a> <div itemprop="about">Histopathology</div> <div itemprop="author">Lopes N,Sousa B,Vieira D,Milanezi F,Schmitt F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the microvessel features in subtype of breast carcinomas</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18490057"> <div itemprop="name">Cypermethrin effects on the adult mice seminal glands.</div> </a> <div itemprop="about">Ecotoxicology and environmental safety</div> <div itemprop="author">Rodriguez H,Tamayo C,Inostroza J,Soto C,Bustos-Obregón E,Paniagua R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of cypermethrin on murine seminal glands</div> <div itemprodp="datePublished">Sun Feb 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19501165"> <div itemprop="name">Permanent impairment of birth and survival of cortical and hippocampal proliferating cells following excessive drinking during alcohol dependence.</div> </a> <div itemprop="about">Neurobiology of disease</div> <div itemprop="author">Richardson HN,Chan SH,Crawford EF,Lee YK,Funk CK,Koob GF,Mandyam CD</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of alcohol consumption on cortical gliogenesis and hippocampal neurogenesis</div> <div itemprodp="datePublished">Thu Oct 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19747744"> <div itemprop="name">Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer.</div> </a> <div itemprop="about">Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology</div> <div itemprop="author">Debucquoy A,Roels S,Goethals L,Libbrecht L,Van Cutsem E,Geboes K,Penninckx F,D'Hoore A,McBride WH,Haustermans K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to perform a phase II clinical trial of the effects of celecoxib in resectable rectal cancer patients treated with radiation plus 5-fluorouracil</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18830127"> <div itemprop="name">A limited panel of immunomarkers can reliably distinguish between clear cell and high-grade serous carcinoma of the ovary.</div> </a> <div itemprop="about">The American journal of surgical pathology</div> <div itemprop="author">Köbel M,Kalloger SE,Carrick J,Huntsman D,Asad H,Oliva E,Ewanowich CA,Soslow RA,Gilks CB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the diagnostic markers of clear cell and high-grade serous carcinoma of the ovary</div> <div itemprodp="datePublished">Thu Jan 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19820025"> <div itemprop="name">Predicting recurrence of nonfunctioning pituitary adenomas.</div> </a> <div itemprop="about">The Journal of clinical endocrinology and metabolism</div> <div itemprop="author">Noh TW,Jeong HJ,Lee MK,Kim TS,Kim SH,Lee EJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study cellular markers that predict the recurrence of nonfunctioning pituitary adenomas</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19261682"> <div itemprop="name">Hecate-CGbeta conjugate and gonadotropin suppression shows two distinct mechanisms of action in the treatment of adrenocortical tumors in transgenic mice expressing Simian Virus 40 T antigen under inhibin-alpha promoter.</div> </a> <div itemprop="about">Endocrine-related cancer</div> <div itemprop="author">Vuorenoja S,Mohanty BP,Arola J,Huhtaniemi I,Toppari J,Rahman NA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the therapeutic potential of a peptide-chorionic gonadotrophin fragement conjugate in adrenocortical tumors</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19435784"> <div itemprop="name">Amplification of the urokinase-type plasminogen activator receptor (uPAR) gene in ductal pancreatic carcinomas identifies a clinically high-risk group.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Hildenbrand R,Niedergethmann M,Marx A,Belharazem D,Allgayer H,Schleger C,Ströbel P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the role of urokinase-type plasminogen activator receptor in the pathogenesis of ductal pancreatic carcinomas</div> <div itemprodp="datePublished">Mon Jun 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19147826"> <div itemprop="name">FoxP3+ regulatory T cells suppress early stages of granuloma formation but have little impact on sarcoidosis lesions.</div> </a> <div itemprop="about">The American journal of pathology</div> <div itemprop="author">Taflin C,Miyara M,Nochy D,Valeyre D,Naccache JM,Altare F,Salek-Peyron P,Badoual C,Bruneval P,Haroche J,Mathian A,Amoura Z,Hill G,Gorochov G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to assess the proliferation levels of Treg cells in blood and in granulomas</div> <div itemprodp="datePublished">Sun Feb 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19797400"> <div itemprop="name">In pursuit of leucine-rich repeat-containing G protein-coupled receptor-5 regulation and function in the uterus.</div> </a> <div itemprop="about">Endocrinology</div> <div itemprop="author">Sun X,Jackson L,Dey SK,Daikoku T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to characterize the uterine leucine-rich repeat-containing G protein-coupled receptor-5</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19095742"> <div itemprop="name">Prolactin treatment improves engraftment and function of transplanted pancreatic islets.</div> </a> <div itemprop="about">Endocrinology</div> <div itemprop="author">Johansson M,Olerud J,Jansson L,Carlsson PO</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the influence of prolactin on pancreatic transplantation</div> <div itemprodp="datePublished">Wed Apr 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19578011"> <div itemprop="name">Comparison of the histology, gene expression profile, and phenotype of cultured human limbal epithelial cells from different limbal regions.</div> </a> <div itemprop="about">Investigative ophthalmology & visual science</div> <div itemprop="author">Utheim TP,Raeder S,Olstad OK,Utheim ØA,de La Paz M,Cheng R,Huynh TT,Messelt E,Roald B,Lyberg T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to compare the celular heterogeneity of epithelial cells derived from various limbal regions</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19561538"> <div itemprop="name">Effect of yeast-derived beta-glucan in conjunction with bevacizumab for the treatment of human lung adenocarcinoma in subcutaneous and orthotopic xenograft models.</div> </a> <div itemprop="about">Journal of immunotherapy (Hagerstown, Md. : 1997)</div> <div itemprop="author">Zhong W,Hansen R,Li B,Cai Y,Salvador C,Moore GD,Yan J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate a combination therapy for human lung adenocarcinoma in subcutaneous and orthotopic xenograft models</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19223760"> <div itemprop="name">EphA2 as a promoter of melanoma tumorigenicity.</div> </a> <div itemprop="about">Cancer biology & therapy</div> <div itemprop="author">Margaryan NV,Strizzi L,Abbott DE,Seftor EA,Rao MS,Hendrix MJ,Hess AR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of EphA2 in melanoma tumorigenicity</div> <div itemprodp="datePublished">Sun Feb 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18855134"> <div itemprop="name">Combination of methylselenocysteine with tamoxifen inhibits MCF-7 breast cancer xenografts in nude mice through elevated apoptosis and reduced angiogenesis.</div> </a> <div itemprop="about">Breast cancer research and treatment</div> <div itemprop="author">Li Z,Carrier L,Belame A,Thiyagarajah A,Salvo VA,Burow ME,Rowan BG</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of methylselenocysteine and tamoxifen on breast cancer cell apoptosis and xenograft angiogenesis</div> <div itemprodp="datePublished">Sun Nov 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19841517"> <div itemprop="name">Synchrotron microbeam radiation therapy for rat brain tumor palliation-influence of the microbeam width at constant valley dose.</div> </a> <div itemprop="about">Physics in medicine and biology</div> <div itemprop="author">Serduc R,Bouchet A,Bräuer-Krisch E,Laissue JA,Spiga J,Sarun S,Bravin A,Fonta C,Renaud L,Boutonnat J,Siegbahn EA,Estève F,Le Duc G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of beam width during Synchrotron microbeam radiation therapy on the survival of gliosarcoma tumor-bearing rats</div> <div itemprodp="datePublished">Sat Nov 07 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19142664"> <div itemprop="name">Distribution and severity of spontaneous lesions in the neuroepithelium and Bowman's glands in mouse olfactory mucosa: age-related progression.</div> </a> <div itemprop="about">Cell and tissue research</div> <div itemprop="author">Kondo K,Watanabe K,Sakamoto T,Suzukawa K,Nibu K,Kaga K,Yamasoba T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the age-related changes of spontaneous lesions in the neuroepithelium and Bowman glands in mouse olfactory mucosa</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19021203"> <div itemprop="name">Keratinocyte-derived chemokine induces prostate epithelial hyperplasia and reactive stroma in a novel transgenic mouse model.</div> </a> <div itemprop="about">The Prostate</div> <div itemprop="author">Schauer IG,Ressler SJ,Rowley DR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to test if overexpressed IL-8 and keratinocyte-derived chemokine induce prostate epithelial hyperplasia and a reactive phenotype</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19095749"> <div itemprop="name">Energetics and mammary carcinogenesis: effects of moderate-intensity running and energy intake on cellular processes and molecular mechanisms in rats.</div> </a> <div itemprop="about">Journal of applied physiology (Bethesda, Md. : 1985)</div> <div itemprop="author">Zhu Z,Jiang W,McGinley JN,Thompson HJ</div> <div itemprop="description">MA5-14520 was used in western blot to investigate the effect of energy manipulations on mammary tumorigenesis</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19591903"> <div itemprop="name">Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain.</div> </a> <div itemprop="about">Neuroscience</div> <div itemprop="author">Yawno T,Hirst JJ,Castillo-Melendez M,Walker DW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of neurosteroids in the development of the fetal brain in late gestation</div> <div itemprodp="datePublished">Tue Oct 20 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19288266"> <div itemprop="name">Targeted genomic disruption of H-ras and N-ras has no effect on early renal changes after unilateral ureteral ligation.</div> </a> <div itemprop="about">World journal of urology</div> <div itemprop="author">Grande MT,Arévalo M,Núñez A,Cannata-Andía JB,Santos E,López-Novoa JM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of targeted genomic disruption of H-ras and N-ras on obstructive nephropathy</div> <div itemprodp="datePublished">Tue Dec 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19245591"> <div itemprop="name">Increased p53 immunoreactivity in proliferative inflammatory atrophy of prostate is related to focal acute inflammation.</div> </a> <div itemprop="about">APMIS : acta pathologica, microbiologica, et immunologica Scandinavica</div> <div itemprop="author">Wang W,Bergh A,Damber JE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of increased p53 immunoreactivity in proliferative inflammatory atrophy</div> <div itemprodp="datePublished">Sun Mar 01 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19703125"> <div itemprop="name">Immunohistochemical expression of SPARC is correlated with recurrence, survival and malignant potential in meningiomas.</div> </a> <div itemprop="about">APMIS : acta pathologica, microbiologica, et immunologica Scandinavica</div> <div itemprop="author">Bozkurt SU,Ayan E,Bolukbasi F,Elmaci I,Pamir N,Sav A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to determine the prognotic significance of SPARC expression in meningioma</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19032938"> <div itemprop="name">Reconstitution activity of hypoxic cultured human cord blood CD34-positive cells in NOG mice.</div> </a> <div itemprop="about">Biochemical and biophysical research communications</div> <div itemprop="author">Shima H,Takubo K,Iwasaki H,Yoshihara H,Gomei Y,Hosokawa K,Arai F,Takahashi T,Suda T</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to investigate the role of hypoxia in the maintenance of hematopoietic stem cells</div> <div itemprodp="datePublished">Fri Jan 16 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19233133"> <div itemprop="name">Craniofacial malformation in R-spondin2 knockout mice.</div> </a> <div itemprop="about">Biochemical and biophysical research communications</div> <div itemprop="author">Yamada W,Nagao K,Horikoshi K,Fujikura A,Ikeda E,Inagaki Y,Kakitani M,Tomizuka K,Miyazaki H,Suda T,Takubo K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the abnormalities of craniofacial structure in R-spondin2 knockout mice</div> <div itemprodp="datePublished">Fri Apr 10 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19703518"> <div itemprop="name">Leukemia inhibitory factor favours neurogenic differentiation of long-term propagated human midbrain precursor cells.</div> </a> <div itemprop="about">Neuroscience letters</div> <div itemprop="author">Andersen RK,Widmer HR,Zimmer J,Wahlberg LU,Meyer M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of leukemia inhibitory factor on the neurogenic differentiation of ventral mesencaphalic precursor cells cultured for extended periods of time</div> <div itemprodp="datePublished">Fri Oct 30 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19838945"> <div itemprop="name">Soy consumption and histopathologic markers in breast tissue using tissue microarrays.</div> </a> <div itemprop="about">Nutrition and cancer</div> <div itemprop="author">Maskarinec G,Erber E,Verheus M,Hernandez BY,Killeen J,Cashin S,Cline JM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to detect effects of soy consumption on markers of tumor proliferation</div> <div itemprodp="datePublished">Fri Jan 15 00:00:00 EST 2010</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19292797"> <div itemprop="name">Prognostic significance of oncogenic markers in ductal carcinoma in situ of the breast: a clinicopathologic study.</div> </a> <div itemprop="about">The breast journal</div> <div itemprop="author">Altintas S,Lambein K,Huizing MT,Braems G,Asjoe FT,Hellemans H,Van Marck E,Weyler J,Praet M,Van den Broecke R,Vermorken JB,Tjalma WA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate oncogenic markers with prognostic significance in breast ductal carcinoma in situ</div> <div itemprodp="datePublished">Wed Jul 08 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19690765"> <div itemprop="name">Diagnostic and differential diagnostic criteria of lymphoid neoplasms in bone marrow trephine biopsies: a study of 87 cases.</div> </a> <div itemprop="about">Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie</div> <div itemprop="author">Horváth E,Mezei T,Pávai Z,Turcu M,Demian S,Tóth E,Chira L,Jung I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the diagnosis of lymphoid neoplasmas through bone marrow trephine biopsies</div> <div itemprodp="datePublished">Wed Dec 16 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20020054"> <div itemprop="name">Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Farioli-Vecchioli S,Saraulli D,Costanzi M,Leonardi L,Cinà I,Micheli L,Nutini M,Longone P,Oh SP,Cestari V,Tirone F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of PC3/Tis21 on hippocampal development and function in mice</div> <div itemprodp="datePublished">Thu Dec 17 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19148298"> <div itemprop="name">Dicer is required for maintaining adult pancreas.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Morita S,Hara A,Kojima I,Horii T,Kimura M,Kitamura T,Ochiya T,Nakanishi K,Matoba R,Matsubara K,Hatada I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Dicer in maintaining the adult pancreas</div> <div itemprodp="datePublished">Mon Mar 23 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/20043822"> <div itemprop="name">Giant cell tumor-like lesion of the urinary bladder: a report of two cases and literature review; giant cell tumor or undifferentiated carcinoma?</div> </a> <div itemprop="about">Diagnostic pathology</div> <div itemprop="author">Behzatoğlu K,Durak H,Canberk S,Aydin O,Huq GE,Oznur M,Ozyalvaçli G,Yildiz P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on two cases of giant cell tumor-like lesion of the urinary bladder</div> <div itemprodp="datePublished">Thu Dec 31 00:00:00 EST 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19716498"> <div itemprop="name">A 19-year follow-up of a patient with type 3 ectrodactyly-ectodermal dysplasia-clefting syndrome who developed non-Hodgkin lymphoma.</div> </a> <div itemprop="about">Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics</div> <div itemprop="author">Balci S,Engiz O,Okten G,Sipahier M,Gursu G,Kandemir B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to perform clinical, radiologic and histopathologic studies of a patient with type 3 ectrodactyly-ectodermal dysplasia-clefting syndrome</div> <div itemprodp="datePublished">Tue Sep 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19523235"> <div itemprop="name">Mammographic density and epithelial histopathologic markers.</div> </a> <div itemprop="about">BMC cancer</div> <div itemprop="author">Verheus M,Maskarinec G,Erber E,Steude JS,Killeen J,Hernandez BY,Cline JM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the association between mammographic density and expression of steroid receptors and proliferation markers in benign breast tissue</div> <div itemprodp="datePublished">Sat Jun 13 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19412421"> <div itemprop="name">Loss of NADPH quinone oxidoreductase in the prostate and enhanced serum levels of cytokine-induced neutrophil chemoattractant 2alpha in hormone-stimulated noble rats: potential role in prostatic intraepithelial neoplasia development.</div> </a> <div itemprop="about">Translational oncology</div> <div itemprop="author">Ghosh R,Schoolfield J,Yeh IT,Smith ML,Hursting SD,Chan DC,Lucia MS,Kumar AP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of NADPH quinone oxidoreductase and cytokine-induced neutrophil chemoattractant 2alpha in prostate cancer development</div> <div itemprodp="datePublished">Fri May 01 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18949633"> <div itemprop="name">Ki-67 in screen-detected, low-grade, low-stage prostate cancer, relation to prostate-specific antigen doubling time, Gleason score and prostate-specific antigen relapse after radical prostatectomy.</div> </a> <div itemprop="about">Scandinavian journal of urology and nephrology</div> <div itemprop="author">Khatami A,Hugosson J,Wang W,Damber JE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the value of Ki-67 in predicting relapse after radical prostatectomy in early prostate cancer</div> <div itemprodp="datePublished">Tue Mar 31 00:00:00 EDT 2009</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18786416"> <div itemprop="name">Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions.</div> </a> <div itemprop="about">Cell stem cell</div> <div itemprop="author">Shen Q,Wang Y,Kokovay E,Lin G,Chuang SM,Goderie SK,Roysam B,Temple S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study whether neural stem cells in the adult subventricular zone are close to blood vessels</div> <div itemprodp="datePublished">Thu Sep 11 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18725988"> <div itemprop="name">Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.</div> </a> <div itemprop="about">The Journal of clinical investigation</div> <div itemprop="author">Carracedo A,Ma L,Teruya-Feldstein J,Rojo F,Salmena L,Alimonti A,Egia A,Sasaki AT,Thomas G,Kozma SC,Papa A,Nardella C,Cantley LC,Baselga J,Pandolfi PP</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which mTORC1 inhibition leads to MAPK pathway activation in human cancer</div> <div itemprodp="datePublished">Mon Sep 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18227220"> <div itemprop="name">Pulmonary arterial remodeling induced by a Th2 immune response.</div> </a> <div itemprop="about">The Journal of experimental medicine</div> <div itemprop="author">Daley E,Emson C,Guignabert C,de Waal Malefyt R,Louten J,Kurup VP,Hogaboam C,Taraseviciene-Stewart L,Voelkel NF,Rabinovitch M,Grunig E,Grunig G</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the role of Th2 immune response in the pathogenesis of pulmonary arterial remodeling</div> <div itemprodp="datePublished">Mon Feb 18 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18395841"> <div itemprop="name">Selective portal vein embolization and ligation trigger different regenerative responses in the rat liver.</div> </a> <div itemprop="about">Hepatology (Baltimore, Md.)</div> <div itemprop="author">Furrer K,Tian Y,Pfammatter T,Jochum W,El-Badry AM,Graf R,Clavien PA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to compare the different effects of portal vein embolization portal vein ligation on the induction of a regenerative response of the remnant liver</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18413840"> <div itemprop="name">Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Verma A,Guha S,Diagaradjane P,Kunnumakkara AB,Sanguino AM,Lopez-Berestein G,Sood AK,Aggarwal BB,Krishnan S,Gelovani JG,Mehta K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the therapeutic potential of tissue transglutaminase inhibition in pancreatic cancer</div> <div itemprodp="datePublished">Tue Apr 15 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18172279"> <div itemprop="name">Combining agents that target the tumor microenvironment improves the efficacy of anticancer therapy.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Blansfield JA,Caragacianu D,Alexander HR,Tangrea MA,Morita SY,Lorang D,Schafer P,Muller G,Stirling D,Royal RE,Libutti SK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the therapeutic potential of combining agents that target the tumor microenvironment</div> <div itemprodp="datePublished">Tue Jan 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18676832"> <div itemprop="name">Neutrophil gelatinase-associated lipocalin: a novel suppressor of invasion and angiogenesis in pancreatic cancer.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Tong Z,Kunnumakkara AB,Wang H,Matsuo Y,Diagaradjane P,Harikumar KB,Ramachandran V,Sung B,Chakraborty A,Bresalier RS,Logsdon C,Aggarwal BB,Krishnan S,Guha S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of neutrophil gelatinase-associated lipocalin in suppressing invasion and angiogenesis in pancreatic cancer</div> <div itemprodp="datePublished">Fri Aug 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18381440"> <div itemprop="name">Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Sawada K,Mitra AK,Radjabi AR,Bhaskar V,Kistner EO,Tretiakova M,Jagadeeswaran S,Montag A,Becker A,Kenny HA,Peter ME,Ramakrishnan V,Yamada SD,Lengyel E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which E-cadherin loss promotes ovarian cancer metastasis</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18593914"> <div itemprop="name">Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Nocito A,Dahm F,Jochum W,Jang JH,Georgiev P,Bader M,Graf R,Clavien PA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the regulation of macrophage-mediated angiogenesis by serotonin in a mouse model of colon cancer</div> <div itemprodp="datePublished">Tue Jul 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18400718"> <div itemprop="name">Effect of n-3 polyunsaturated fatty acids on Barrett's epithelium in the human lower esophagus.</div> </a> <div itemprop="about">The American journal of clinical nutrition</div> <div itemprop="author">Mehta SP,Boddy AP,Cook J,Sams V,Lund EK,Johnson IT,Rhodes M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects the n-3 fatty acid eicosapentaenoic acid on a number of biological endpoints in Barrett's esophagus</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18194560"> <div itemprop="name">Can clinically relevant prognostic subsets of breast cancer patients with four or more involved axillary lymph nodes be identified through immunohistochemical biomarkers? A tissue microarray feasibility study.</div> </a> <div itemprop="about">Breast cancer research : BCR</div> <div itemprop="author">Crabb SJ,Bajdik CD,Leung S,Speers CH,Kennecke H,Huntsman DG,Gelmon KA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to identify prognostic biomarkers for breast cancer involving 4 or more auxilliary lymph nodes</div> <div itemprodp="datePublished">Wed Jun 11 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17917670"> <div itemprop="name">Diagnostic and prognostic markers for gastrointestinal stromal tumors in Norway.</div> </a> <div itemprop="about">Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc</div> <div itemprop="author">Steigen SE,Bjerkehagen B,Haugland HK,Nordrum IS,Løberg EM,Isaksen V,Eide TJ,Nielsen TO</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to confirm several diagnostic markers for gastrointestinal stromal tumors in Norway</div> <div itemprodp="datePublished">Tue Jan 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18311112"> <div itemprop="name">Human ASH1 expression in prostate cancer with neuroendocrine differentiation.</div> </a> <div itemprop="about">Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc</div> <div itemprop="author">Rapa I,Ceppi P,Bollito E,Rosas R,Cappia S,Bacillo E,Porpiglia F,Berruti A,Papotti M,Volante M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the expression of human ASH1 in prostate cancer with neuroendocrine differentiation</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18371177"> <div itemprop="name">Phenotypic and genotypic characterization of orthotopic human glioma models and its relevance for the study of anti-glioma therapy.</div> </a> <div itemprop="about">Brain pathology (Zurich, Switzerland)</div> <div itemprop="author">Claes A,Schuuring J,Boots-Sprenger S,Hendriks-Cornelissen S,Dekkers M,van der Kogel AJ,Leenders WP,Wesseling P,Jeuken JW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate murine models of human glioma</div> <div itemprodp="datePublished">Tue Jul 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18081012"> <div itemprop="name">Magnetic resonance imaging-based detection of glial brain tumors in mice after antiangiogenic treatment.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Claes A,Gambarota G,Hamans B,van Tellingen O,Wesseling P,Maass C,Heerschap A,Leenders W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to detect glial brain tumors after antigangiogenic treatment by magnetic resonance imaging</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18223201"> <div itemprop="name">Cux2 (Cutl2) integrates neural progenitor development with cell-cycle progression during spinal cord neurogenesis.</div> </a> <div itemprop="about">Development (Cambridge, England)</div> <div itemprop="author">Iulianella A,Sharma M,Durnin M,Vanden Heuvel GB,Trainor PA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the role of Cux2 during spinal cord neurogenesis</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18599502"> <div itemprop="name">Lung EC-SOD overexpression attenuates hypoxic induction of Egr-1 and chronic hypoxic pulmonary vascular remodeling.</div> </a> <div itemprop="about">American journal of physiology. Lung cellular and molecular physiology</div> <div itemprop="author">Nozik-Grayck E,Suliman HB,Majka S,Albietz J,Van Rheen Z,Roush K,Stenmark KR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the involvement of extracellular superoxide dismutase in chronic hypoxia-induced pulmonary hypertension</div> <div itemprodp="datePublished">Mon Sep 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18413795"> <div itemprop="name">Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy.</div> </a> <div itemprop="about">Molecular cancer therapeutics</div> <div itemprop="author">Zhang C,Lundgren K,Yan Z,Arango ME,Price S,Huber A,Higgins J,Troche G,Skaptason J,Koudriakova T,Nonomiya J,Yang M,O'Connor P,Bender S,Los G,Lewis C,Jessen B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the pharmacology of a novel a pan-Cdk inhibitor with antitumor activity</div> <div itemprodp="datePublished">Tue Apr 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18509000"> <div itemprop="name">Estrogen promotes tumor progression in a genetically defined mouse model of lung adenocarcinoma.</div> </a> <div itemprop="about">Endocrine-related cancer</div> <div itemprop="author">Hammoud Z,Tan B,Badve S,Bigsby RM</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to use a genetically defined murine lung adenocarcinoma model to study the effects of estrogen on tumor progression</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18377897"> <div itemprop="name">Effect of leukemia inhibitory factor on long-term propagation of precursor cells derived from rat forebrain subventricular zone and ventral mesencephalon.</div> </a> <div itemprop="about">Experimental neurology</div> <div itemprop="author">Andersen RK,Zimmer J,Wahlberg LU,Meyer M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of leukemia inhibitory factor on the propagation of neuronal precursor cells</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18431237"> <div itemprop="name">Dearterialization of the liver causes intrahepatic cholestasis due to reduced bile transporter expression.</div> </a> <div itemprop="about">Transplantation</div> <div itemprop="author">Hoekstra H,Tian Y,Jochum W,Stieger B,Graf R,Porte RJ,Clavien PA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of bile acid transporter expression in liver injury after hepatic artery thrombosis</div> <div itemprodp="datePublished">Sun Apr 27 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18397998"> <div itemprop="name">Inhibition of beta-catenin signaling causes defects in postnatal cartilage development.</div> </a> <div itemprop="about">Journal of cell science</div> <div itemprop="author">Chen M,Zhu M,Awad H,Li TF,Sheu TJ,Boyce BF,Chen D,O'Keefe RJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of beta-catenin in postnatal skeletal growth and development</div> <div itemprodp="datePublished">Thu May 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18391012"> <div itemprop="name">Distinct expression and function of alternatively spliced Tbx5 isoforms in cell growth and differentiation.</div> </a> <div itemprop="about">Molecular and cellular biology</div> <div itemprop="author">Georges R,Nemer G,Morin M,Lefebvre C,Nemer M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of Tbx5 isoforms in cell growth and differentiation</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18065723"> <div itemprop="name">Foxg1 haploinsufficiency reduces the population of cortical intermediate progenitor cells: effect of increased p21 expression.</div> </a> <div itemprop="about">Cerebral cortex (New York, N.Y. : 1991)</div> <div itemprop="author">Siegenthaler JA,Tremper-Wells BA,Miller MW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effects of Foxg1 haploinsufficiency on the population of cortical intermediate progenitor cells</div> <div itemprodp="datePublished">Fri Aug 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18936203"> <div itemprop="name">Mechanisms associated with dose-dependent inhibition of rat mammary carcinogenesis by dry bean (Phaseolus vulgaris, L.).</div> </a> <div itemprop="about">The Journal of nutrition</div> <div itemprop="author">Thompson MD,Thompson HJ,Brick MA,McGinley JN,Jiang W,Zhu Z,Wolfe P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the mechanisms for the effect of dry bean on rat mammary carcinogenesis</div> <div itemprodp="datePublished">Sat Nov 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18841391"> <div itemprop="name">Activated Akt as an indicator of prognosis in gastric cancer.</div> </a> <div itemprop="about">Virchows Archiv : an international journal of pathology</div> <div itemprop="author">Cinti C,Vindigni C,Zamparelli A,La Sala D,Epistolato MC,Marrelli D,Cevenini G,Tosi P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the prognostic significance of activated AKT in gastric cancer</div> <div itemprodp="datePublished">Sat Nov 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18253944"> <div itemprop="name">Bone marrow-derived cells expressing Iba1 are constitutively present as resident tissue macrophages in the mouse cochlea.</div> </a> <div itemprop="about">Journal of neuroscience research</div> <div itemprop="author">Okano T,Nakagawa T,Kita T,Kada S,Yoshimoto M,Nakahata T,Ito J</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the expression of Iba1 in bone marrow-derived cells in the mouse cochlea</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18367503"> <div itemprop="name">Expression of NANOG, but not POU5F1, points to the stem cell potential of primitive germ cells in neonatal pig testis.</div> </a> <div itemprop="about">Reproduction (Cambridge, England)</div> <div itemprop="author">Goel S,Fujihara M,Minami N,Yamada M,Imai H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the relationship between NANOG expression and pluripotency of primitive germ cells in neonatal pig testis</div> <div itemprodp="datePublished">Sun Jun 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18657296"> <div itemprop="name">Coordinated expression of activated mitogen-activated protein kinases in salivary gland adenoid cystic carcinoma.</div> </a> <div itemprop="about">Human pathology</div> <div itemprop="author">Handra-Luca A,Mauguen A,Ménard P,Fouret P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the expression of phosphorylated forms of mitogen-activated protein kinases in salivary gland adenoid cystic carcinoma</div> <div itemprodp="datePublished">Sat Nov 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18173712"> <div itemprop="name">Combination therapy with antiangiogenic treatment and photodynamic therapy for the nude mouse bearing U87 glioblastoma.</div> </a> <div itemprop="about">Photochemistry and photobiology</div> <div itemprop="author">Jiang F,Zhang X,Kalkanis SN,Zhang Z,Yang H,Katakowski M,Hong X,Zheng X,Zhu Z,Chopp M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the efficacy of combination therapy with antiangiogenic treatment and photodynamic therapy in glioblastoma</div> <div itemprodp="datePublished">Thu Mar 27 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18704591"> <div itemprop="name">Imaging proliferation to monitor early response of lymphoma to cytotoxic treatment.</div> </a> <div itemprop="about">Molecular imaging and biology</div> <div itemprop="author">Graf N,Herrmann K,den Hollander J,Fend F,Schuster T,Wester HJ,Senekowitsch-Schmidtke R,zum Büschenfelde CM,Peschel C,Schwaiger M,Dechow T,Buck AK</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the application of thymidine analogue 3'-deoxy-3'-[18F]fluorothymidine in positron emission tomography imaging of nucleoside metabolism</div> <div itemprodp="datePublished">Thu Dec 11 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18216579"> <div itemprop="name">Regeneration with proliferation of the endothelium of cultured human donor corneas with extended postmortem time.</div> </a> <div itemprop="about">Cornea</div> <div itemprop="author">Slettedal JK,Lyberg T,Røger M,Beraki K,Ramstad H,Nicolaissen B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the survival time of the corneal endothelium postmortem</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18498087"> <div itemprop="name">HDAC4 inhibits cell-cycle progression and protects neurons from cell death.</div> </a> <div itemprop="about">Developmental neurobiology</div> <div itemprop="author">Majdzadeh N,Wang L,Morrison BE,Bassel-Duby R,Olson EN,D'Mello SR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of HDAC4 on cell-cycle progression and cell survival</div> <div itemprodp="datePublished">Tue Jul 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19134051"> <div itemprop="name">An intravital microscopic study of the hepatic microcirculation in cirrhotic mice models: relationship between fibrosis and angiogenesis.</div> </a> <div itemprop="about">International journal of experimental pathology</div> <div itemprop="author">Vanheule E,Geerts AM,Van Huysse J,Schelfhout D,Praet M,Van Vlierberghe H,De Vos M,Colle I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the relationship between angiogenesis in liver and cirrhogenesis</div> <div itemprodp="datePublished">Mon Dec 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18781631"> <div itemprop="name">Serdin1/Lrrc10 is dispensable for mouse development.</div> </a> <div itemprop="about">Genesis (New York, N.Y. : 2000)</div> <div itemprop="author">Manuylov NL,Manuylova E,Avdoshina V,Tevosian S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the function of Serdin1/Lrrc10 in mouse cardiac development</div> <div itemprodp="datePublished">Mon Sep 01 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18498286"> <div itemprop="name">Immunohistochemical and ultrastructural characterization of brain tumors in S100beta-v-erbB transgenic rats.</div> </a> <div itemprop="about">Neuropathology : official journal of the Japanese Society of Neuropathology</div> <div itemprop="author">Yokoo H,Tanaka Y,Nobusawa S,Nakazato Y,Ohgaki H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the characteristic of brain tumors in S100beta-v-erbB transgenic rats</div> <div itemprodp="datePublished">Mon Dec 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18337230"> <div itemprop="name">Applications of laser scanning cytometry in immunohistochemistry and routine histopathology.</div> </a> <div itemprop="about">Toxicologic pathology</div> <div itemprop="author">Peterson RA,Krull DL,Butler L</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate laser scanning cytometry for routine histopathological analysis</div> <div itemprodp="datePublished">Tue Jan 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18349427"> <div itemprop="name">Chronic microcystin exposure induces hepatocyte proliferation with increased expression of mitotic and cyclin-associated genes in P53-deficient mice.</div> </a> <div itemprop="about">Toxicologic pathology</div> <div itemprop="author">Clark SP,Ryan TP,Searfoss GH,Davis MA,Hooser SB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of chronic exposure to microcystin on hepatocyte proliferation in p53-deficient mice</div> <div itemprodp="datePublished">Fri Feb 01 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18758634"> <div itemprop="name">Plasmoblastic lymphoma associated with human immunodeficiency virus.</div> </a> <div itemprop="about">Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie</div> <div itemprop="author">Horváth E,Krenács L,Bagdi E,Pávai Z,Macarie I,Nagy EE,Demian S</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the association of plasmoblastic lymphoma with human immunodeficiency virus</div> <div itemprodp="datePublished">Thu Dec 11 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18552977"> <div itemprop="name">Down-regulation of Notch signaling during corneal epithelial proliferation.</div> </a> <div itemprop="about">Molecular vision</div> <div itemprop="author">Djalilian AR,Namavari A,Ito A,Balali S,Afshar A,Lavker RM,Yue BY</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study Notch pathway expression and activation in the adult corneal epithelium during proliferation</div> <div itemprodp="datePublished">Thu Jun 05 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18334483"> <div itemprop="name">The CB(2) cannabinoid receptor controls myeloid progenitor trafficking: involvement in the pathogenesis of an animal model of multiple sclerosis.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Palazuelos J,Davoust N,Julien B,Hatterer E,Aguado T,Mechoulam R,Benito C,Romero J,Silva A,Guzmán M,Nataf S,Galve-Roperh I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of CB2 cannabinoid receptor on the pathogenesis of multiple sclerosis</div> <div itemprodp="datePublished">Fri May 09 00:00:00 EDT 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/19087265"> <div itemprop="name">Patterning of palatal rugae through sequential addition reveals an anterior/posterior boundary in palatal development.</div> </a> <div itemprop="about">BMC developmental biology</div> <div itemprop="author">Pantalacci S,Prochazka J,Martin A,Rothova M,Lambert A,Bernard L,Charles C,Viriot L,Peterkova R,Laudet V</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the process of rugae development in mouse</div> <div itemprodp="datePublished">Tue Dec 16 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17906636"> <div itemprop="name">Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors.</div> </a> <div itemprop="about">Nature medicine</div> <div itemprop="author">Soucek L,Lawlor ER,Soto D,Shchors K,Swigart LB,Evan GI</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of mast cells in Myc-induced pancreatic islet tumors</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17482546"> <div itemprop="name">p63 Is essential for the proliferative potential of stem cells in stratified epithelia.</div> </a> <div itemprop="about">Cell</div> <div itemprop="author">Senoo M,Pinto F,Crum CP,McKeon F</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the role of p63 in the proliferative activity of stratified epithelia stem cells</div> <div itemprodp="datePublished">Fri May 04 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17038534"> <div itemprop="name">Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity.</div> </a> <div itemprop="about">Blood</div> <div itemprop="author">Smit LA,Hallaert DY,Spijker R,de Goeij B,Jaspers A,Kater AP,van Oers MH,van Noesel CJ,Eldering E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of Noxa expression in the pathogenesis of chronic lymphocytic leukemia</div> <div itemprodp="datePublished">Thu Feb 15 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17575237"> <div itemprop="name">Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Gendreau SB,Ventura R,Keast P,Laird AD,Yakes FM,Zhang W,Bentzien F,Cancilla B,Lutman J,Chu F,Jackman L,Shi Y,Yu P,Wang J,Aftab DT,Jaeger CT,Meyer SM,De Costa A,Engell K,Chen J,Martini JF,Joly AH</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the inhibitory effect of EXEL-7647 on the activity of wild-type and mutant EGFR</div> <div itemprodp="datePublished">Fri Jun 15 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17473212"> <div itemprop="name">Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model mediated by Nexrutine, a Phellodendron amurense bark extract.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Kumar AP,Bhaskaran S,Ganapathy M,Crosby K,Davis MD,Kochunov P,Schoolfield J,Yeh IT,Troyer DA,Ghosh R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the Akt/cAMP-responsive element binding protein/cyclin D1 network in the inhibition of prostate cancer by Nexrutine in a mouse model</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17440100"> <div itemprop="name">Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Kunnumakkara AB,Guha S,Krishnan S,Diagaradjane P,Gelovani J,Aggarwal BB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanism by which curcumin potentiates the antitumor activity of gemcitabine in a model of pancreatic cancer</div> <div itemprodp="datePublished">Sun Apr 15 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17566110"> <div itemprop="name">The properties of a mammary gland cancer stem cell.</div> </a> <div itemprop="about">Proceedings of the National Academy of Sciences of the United States of America</div> <div itemprop="author">Zucchi I,Sanzone S,Astigiano S,Pelucchi P,Scotti M,Valsecchi V,Barbieri O,Bertoli G,Albertini A,Reinbold RA,Dulbecco R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the properties of a single mammary gland cancer stem cell</div> <div itemprodp="datePublished">Tue Jun 19 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17612586"> <div itemprop="name">Generation and expansion of multipotent mesenchymal progenitor cells from cultured human pancreatic islets.</div> </a> <div itemprop="about">Cell death and differentiation</div> <div itemprop="author">Gallo R,Gambelli F,Gava B,Sasdelli F,Tellone V,Masini M,Marchetti P,Dotta F,Sorrentino V</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to examine the capability of cultured human pancreatic islets to yield multipotent mesenchymal progenitor cells</div> <div itemprodp="datePublished">Thu Nov 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17406853"> <div itemprop="name">Improved vascular engraftment and function of autotransplanted pancreatic islets as a result of partial pancreatectomy in the mouse and rat.</div> </a> <div itemprop="about">Diabetologia</div> <div itemprop="author">Johansson M,Jansson L,Carlsson PO</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the effect of surgical tissue trauma on the function of autotransplanted pancreatic islets</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17611019"> <div itemprop="name">The anticancer prodrugs of butyric acid AN-7 and AN-9, possess antiangiogenic properties.</div> </a> <div itemprop="about">Cancer letters</div> <div itemprop="author">Blank-Porat D,Gruss-Fischer T,Tarasenko N,Malik Z,Nudelman A,Rephaeli A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the anti-angiogenic properties of the anticancer prodrugs of butyric acid AN-7 and AN-9</div> <div itemprodp="datePublished">Thu Oct 18 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17043660"> <div itemprop="name">Snail silencing effectively suppresses tumour growth and invasiveness.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Olmeda D,Jordá M,Peinado H,Fabra A,Cano A</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the suppressive effect of Snail silencing on tumour growth and invasiveness</div> <div itemprodp="datePublished">Thu Mar 22 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17230415"> <div itemprop="name">Simian immunodeficiency virus-induced lymphatic tissue fibrosis is mediated by transforming growth factor beta 1-positive regulatory T cells and begins in early infection.</div> </a> <div itemprop="about">The Journal of infectious diseases</div> <div itemprop="author">Estes JD,Wietgrefe S,Schacker T,Southern P,Beilman G,Reilly C,Milush JM,Lifson JD,Sodora DL,Carlis JV,Haase AT</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry and immunohistochemistry to study the role of TGF-beta1-positive regulatory T cells in SIV-induced lymphatic tissue fibrosis</div> <div itemprodp="datePublished">Thu Feb 15 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17616990"> <div itemprop="name">The contribution of bifunctional SkipDewax pretreatment solution, rabbit monoclonal antibodies, and polymer detection systems in immunohistochemistry.</div> </a> <div itemprop="about">Archives of pathology & laboratory medicine</div> <div itemprop="author">Wong SC,Chan JK,Lo ES,Chan AK,Wong MC,Chan CM,Lam MY,Chan AT</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate novel immunohistochemistry reagents and techniques</div> <div itemprodp="datePublished">Sun Jul 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17303223"> <div itemprop="name">Objective risk definition for endometrial lesion spectrum: a diagnostic algorithm.</div> </a> <div itemprop="about">Gynecologic oncology</div> <div itemprop="author">Yilmaz I,Baloglu H,Haholu A,Berber U,Yildirim S,Ergur AR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate a prognostic algorithm for endometrial lesion spectrum</div> <div itemprodp="datePublished">Tue May 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17341866"> <div itemprop="name">The efficacy and safety of topically applied indigo naturalis ointment in patients with plaque-type psoriasis.</div> </a> <div itemprop="about">Dermatology (Basel, Switzerland)</div> <div itemprop="author">Lin YK,Wong WR,Chang YC,Chang CJ,Tsay PK,Chang SC,Pang JH</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the potential therapeutic effects of topical indigo naturalis in plaque-type psoriasis</div> <div itemprodp="datePublished">Wed May 16 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17660399"> <div itemprop="name">Role of alpha1beta1-integrin in arterial stiffness and angiotensin-induced arterial wall hypertrophy in mice.</div> </a> <div itemprop="about">American journal of physiology. Heart and circulatory physiology</div> <div itemprop="author">Louis H,Kakou A,Regnault V,Labat C,Bressenot A,Gao-Li J,Gardner H,Thornton SN,Challande P,Li Z,Lacolley P</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the effect of alpha(1)beta(1)-integrin on p38 MAPK and FAK phosphorylation and its role in the vascular abnormalities</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17494055"> <div itemprop="name">Epidermal hyperplasia and papillomatosis in mice with a keratinocyte-restricted deletion of csk.</div> </a> <div itemprop="about">Carcinogenesis</div> <div itemprop="author">Honda K,Sakaguchi T,Sakai K,Schmedt C,Ramirez A,Jorcano JL,Tarakhovsky A,Kamisoyama H,Sakai T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of csk in epidermal hyperplasia and papillomatosis</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17443290"> <div itemprop="name">Ferumoxtran-10 enhancement in orthotopic xenograft models of human brain tumors: an indirect marker of tumor proliferation?</div> </a> <div itemprop="about">Journal of neuro-oncology</div> <div itemprop="author">Kremer S,Pinel S,Védrine PO,Bressenot A,Robert P,Bracard S,Plénat F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the utility of a contrasting agent ferumoxtran-10 in tumor diagnosis</div> <div itemprodp="datePublished">Fri Jun 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16816171"> <div itemprop="name">Microvascular proliferation in congenital vascular malformations of skin and soft tissue.</div> </a> <div itemprop="about">Journal of clinical pathology</div> <div itemprop="author">Meijer-Jorna LB,van der Loos CM,de Boer OJ,van der Horst CM,van der Wal AC</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study microvascular proliferation in surgically treated congenital vascular malformations</div> <div itemprodp="datePublished">Sun Jul 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17442359"> <div itemprop="name">Involvement of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice.</div> </a> <div itemprop="about">Toxicology and applied pharmacology</div> <div itemprop="author">Okano J,Suzuki S,Shiota K</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of apoptotic cell death and cell cycle perturbation in retinoic acid-induced cleft palate in mice</div> <div itemprodp="datePublished">Tue May 15 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17115102"> <div itemprop="name">Anaplastic thyroid carcinoma: expression profile of targets for therapy offers new insights for disease treatment.</div> </a> <div itemprop="about">Annals of surgical oncology</div> <div itemprop="author">Wiseman SM,Masoudi H,Niblock P,Turbin D,Rajput A,Hay J,Bugis S,Filipenko D,Huntsman D,Gilks B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to search therapical targets for the treatment of anaplastic thyroid carcinoma</div> <div itemprodp="datePublished">Thu Feb 01 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17512930"> <div itemprop="name">Cellular responses to disruption of the permeability barrier in a three-dimensional organotypic epidermal model.</div> </a> <div itemprop="about">Experimental cell research</div> <div itemprop="author">Ajani G,Sato N,Mack JA,Maytin EV</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the role of permeability barrier breach in epidermal hyperplasia</div> <div itemprodp="datePublished">Wed Aug 15 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17570496"> <div itemprop="name">Increased expression of CCAAT/enhancer-binding protein beta in proliferative inflammatory atrophy of the prostate: relation with the expression of COX-2, the androgen receptor, and presence of focal chronic inflammation.</div> </a> <div itemprop="about">The Prostate</div> <div itemprop="author">Wang W,Bergh A,Damber JE</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the mechanisms driving increased expression of C/EBPbeta in proliferative inflammatory atrophy of the prostate</div> <div itemprodp="datePublished">Wed Aug 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18088275"> <div itemprop="name">Contrasting effects of basic fibroblast growth factor and epidermal growth factor on mouse neonatal olfactory mucosa cells.</div> </a> <div itemprop="about">The European journal of neuroscience</div> <div itemprop="author">Barraud P,He X,Zhao C,Ibanez C,Raha-Chowdhury R,Caldwell MA,Franklin RJ</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the effects of bFGF and EGF on mouse neonatal olfactory mucosa cells</div> <div itemprodp="datePublished">Sat Dec 01 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17521702"> <div itemprop="name">The Y-encoded TSPY protein: a significant marker potentially plays a role in the pathogenesis of testicular germ cell tumors.</div> </a> <div itemprop="about">Human pathology</div> <div itemprop="author">Li Y,Tabatabai ZL,Lee TL,Hatakeyama S,Ohyama C,Chan WY,Looijenga LH,Lau YF</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of the Y-encoded TSPY protein in the pathogenesis of testicular germ cell tumors</div> <div itemprodp="datePublished">Mon Oct 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17572515"> <div itemprop="name">Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models.</div> </a> <div itemprop="about">Behavioural brain research</div> <div itemprop="author">Yang H,Chopp M,Zhang X,Jiang F,Zhang Z,Kalkanis S,Schallert T</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the use of behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models</div> <div itemprodp="datePublished">Wed Aug 22 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17413989"> <div itemprop="name">Lymphoma-like lesion of the uterine cervix: report of 12 cases of a rare entity.</div> </a> <div itemprop="about">International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists</div> <div itemprop="author">Ma J,Shi QL,Zhou XJ,Meng K,Chen JY,Huang WB</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the clinicopathologic features of 12 clinical cases of lymphoma-like lesions of the uterine cervix</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17667617"> <div itemprop="name">Expression of glucose transporter protein-1 (Glut-1) in ocular surface squamous neoplasia.</div> </a> <div itemprop="about">Cornea</div> <div itemprop="author">Gurses I,Doganay S,Mizrak B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study GLUT-1 glucose transporter expression in ocular surface squamous neoplasia</div> <div itemprodp="datePublished">Wed Aug 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17470174"> <div itemprop="name">Nested variant of transitional cell carcinoma with osseous metaplasia of the urinary bladder: a case report and review of published reports.</div> </a> <div itemprop="about">International journal of urology : official journal of the Japanese Urological Association</div> <div itemprop="author">Neşe N,Kandiloğlu AR,Atesçi YZ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to report on a case of a nested variant of transitional cell carcinoma with osseous metaplasia of the urinary bladder</div> <div itemprodp="datePublished">Sun Apr 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17505777"> <div itemprop="name">Post-acute response of 9L gliosarcoma to Photofrin-mediated PDT in athymic nude mice.</div> </a> <div itemprop="about">Lasers in medical science</div> <div itemprop="author">Zhang X,Jiang F,Kalkanis SN,Zhang Z,Hong X,Yang H,Chopp M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the post-acute response of 9L gliosarcoma to Photofrin-mediated photodynamic therapy in athymic nude mice</div> <div itemprodp="datePublished">Thu Nov 01 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/18035936"> <div itemprop="name">Prognostic significance of cell proliferation and apoptosis-regulating proteins in Epstein-Barr virus positive and negative pediatric Hodgkin lymphoma.</div> </a> <div itemprop="about">Lymphatic research and biology</div> <div itemprop="author">Aktaş S,Kargi A,Olgun N,Diniz G,Erbay A,Vergin C</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to evaluate prognostic markers for Epstein-Barr virus positive and negative pediatric Hodgkin lymphoma</div> <div itemprodp="datePublished">Mon Mar 03 00:00:00 EST 2008</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17929992"> <div itemprop="name">The intermediate filament nestin is highly expressed in normal human podocytes and podocytes in glomerular disease.</div> </a> <div itemprop="about">Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society</div> <div itemprop="author">Perry J,Ho M,Viero S,Zheng K,Jacobs R,Thorner PS</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to study the expression of nestin in human podocytes in health and in glomerular disease</div> <div itemprodp="datePublished">Wed Dec 12 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17202146"> <div itemprop="name">Cannabinoids induce glioma stem-like cell differentiation and inhibit gliomagenesis.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Aguado T,Carracedo A,Julien B,Velasco G,Milman G,Mechoulam R,Alvarez L,Guzmán M,Galve-Roperh I</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry to investigate the effect of cannabinoids on glioma stem-like cell differentiation and gliomagenesis</div> <div itemprodp="datePublished">Fri Mar 02 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17206865"> <div itemprop="name">A role for Alström syndrome protein, alms1, in kidney ciliogenesis and cellular quiescence.</div> </a> <div itemprop="about">PLoS genetics</div> <div itemprop="author">Li G,Vega R,Nelms K,Gekakis N,Goodnow C,McNamara P,Wu H,Hong NA,Glynne R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the Alström syndrome protein alms1 in kidney ciliogenesis and cellular quiescence</div> <div itemprodp="datePublished">Fri Jan 05 00:00:00 EST 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17556369"> <div itemprop="name">The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Aguado T,Romero E,Monory K,Palazuelos J,Sendtner M,Marsicano G,Lutz B,Guzmán M,Galve-Roperh I</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of CB1 cannabinoid receptor in neural progenitor proliferation and neurogenesis</div> <div itemprodp="datePublished">Fri Aug 17 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17925854"> <div itemprop="name">SIRNA-directed in vivo silencing of androgen receptor inhibits the growth of castration-resistant prostate carcinomas.</div> </a> <div itemprop="about">PloS one</div> <div itemprop="author">Compagno D,Merle C,Morin A,Gilbert C,Mathieu JR,Bozec A,Mauduit C,Benahmed M,Cabon F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of the androgen receptor in inhibiting the growth of castration-resistant prostate carcinomas</div> <div itemprodp="datePublished">Wed Oct 10 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17157790"> <div itemprop="name">Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo.</div> </a> <div itemprop="about">Cancer cell</div> <div itemprop="author">Ringshausen I,O'Shea CC,Finch AJ,Swigart LB,Evan GI</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of Mdm2 in the regulation of p53 activity in vivo</div> <div itemprodp="datePublished">Fri Dec 01 00:00:00 EST 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16628673"> <div itemprop="name">Bile salt toxicity aggravates cold ischemic injury of bile ducts after liver transplantation in Mdr2+/- mice.</div> </a> <div itemprop="about">Hepatology (Baltimore, Md.)</div> <div itemprop="author">Hoekstra H,Porte RJ,Tian Y,Jochum W,Stieger B,Moritz W,Slooff MJ,Graf R,Clavien PA</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of bile salt toxicity on cold ischemic bile duct injury after liver transplantation in multidrug resistance 2 (+/-) mice</div> <div itemprodp="datePublished">Mon May 01 00:00:00 EDT 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16740778"> <div itemprop="name">Ionizing radiation antagonizes tumor hypoxia induced by antiangiogenic treatment.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Riesterer O,Honer M,Jochum W,Oehler C,Ametamey S,Pruschy M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of ionizing radiation in antagonizing tumor hypoxia induced by antiangiogenic treatment</div> <div itemprodp="datePublished">Thu Jun 01 00:00:00 EDT 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16585203"> <div itemprop="name">Selective inhibition of ErbB2-overexpressing breast cancer in vivo by a novel TAT-based ErbB2-targeting signal transducers and activators of transcription 3-blocking peptide.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Tan M,Lan KH,Yao J,Lu CH,Sun M,Neal CL,Lu J,Yu D</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to develop a new peptide delivery system for the targeted therapy of breast cancer overexpressing ErbB2</div> <div itemprodp="datePublished">Sat Apr 01 00:00:00 EST 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16673374"> <div itemprop="name">Transcription factor co-expression patterns indicate heterogeneity of oligodendroglial subpopulations in adult spinal cord.</div> </a> <div itemprop="about">Glia</div> <div itemprop="author">Kitada M,Rowitch DH</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study transcription factor co-expression patterns and heterogeneity of oligodendroglial subpopulations in adult spinal cord</div> <div itemprodp="datePublished">Sat Jul 01 00:00:00 EDT 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16217746"> <div itemprop="name">Heparanase promotes growth, angiogenesis and survival of primary breast tumors.</div> </a> <div itemprop="about">International journal of cancer</div> <div itemprop="author">Cohen I,Pappo O,Elkin M,San T,Bar-Shavit R,Hazan R,Peretz T,Vlodavsky I,Abramovitch R</div> <div itemprop="description">MA5-14520 was used in western blot to investigate the role of heparanase in breast tumors</div> <div itemprodp="datePublished">Sat Apr 01 00:00:00 EST 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16679381"> <div itemprop="name">Enhancement of angiogenic effectors through hypoxia-inducible factor in preterm primate lung in vivo.</div> </a> <div itemprop="about">American journal of physiology. Lung cellular and molecular physiology</div> <div itemprop="author">Asikainen TM,Waleh NS,Schneider BK,Clyman RI,White CW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the enhancement of angiogenic effectors by HIF-1 in preterm primate lung in vivo</div> <div itemprodp="datePublished">Sun Oct 01 00:00:00 EDT 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16552817"> <div itemprop="name">Effects of retrorsine on mouse hepatocyte proliferation after liver injury.</div> </a> <div itemprop="about">World journal of gastroenterology</div> <div itemprop="author">Zhou XF,Wang Q,Chu JX,Liu AL</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of retrorsine on the proliferation of mouse hepatocyte</div> <div itemprodp="datePublished">Tue Mar 07 00:00:00 EST 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/17308358"> <div itemprop="name">Immunohistochemical separation of follicular variant of papillary thyroid carcinoma from follicular adenoma.</div> </a> <div itemprop="about">Endocrine pathology</div> <div itemprop="author">Nakamura N,Erickson LA,Jin L,Kajita S,Zhang H,Qian X,Rumilla K,Lloyd RV</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the differences between follicular adenoma and follicular variant of papillary thyroid carcinoma</div> <div itemprodp="datePublished">Thu Mar 29 00:00:00 EDT 2007</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16683984"> <div itemprop="name">A three-dimensional model of differentiation of immortalized human bronchial epithelial cells.</div> </a> <div itemprop="about">Differentiation; research in biological diversity</div> <div itemprop="author">Vaughan MB,Ramirez RD,Wright WE,Minna JD,Shay JW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to examine the differentiation potential of immortalized human bronchial epithelial cells</div> <div itemprodp="datePublished">Sat Apr 01 00:00:00 EST 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16984728"> <div itemprop="name">Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model.</div> </a> <div itemprop="about">Neoplasia (New York, N.Y.)</div> <div itemprop="author">Borowsky AD,Dingley KH,Ubick E,Turteltaub KW,Cardiff RD,Devere-White R</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to validate PhIP-induced rat prostatic neoplasia as a model of human prostate cancer progression</div> <div itemprodp="datePublished">Fri Sep 01 00:00:00 EDT 2006</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16120817"> <div itemprop="name">The kd/kd mouse is a model of collapsing glomerulopathy.</div> </a> <div itemprop="about">Journal of the American Society of Nephrology : JASN</div> <div itemprop="author">Barisoni L,Madaio MP,Eraso M,Gasser DL,Nelson PJ</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the possible usage of kd/kd mouse as a research tool for collapsing glomerulopathy</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16361565"> <div itemprop="name">Antitumor efficacy of capecitabine and celecoxib in irradiated and lead-shielded, contralateral human BxPC-3 pancreatic cancer xenografts: clinical implications of abscopal effects.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Blanquicett C,Saif MW,Buchsbaum DJ,Eloubeidi M,Vickers SM,Chhieng DC,Carpenter MD,Sellers JC,Russo S,Diasio RB,Johnson MR</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the abscopal effect of X-ray therapy on BxPC-3 xenografts in nude mice</div> <div itemprodp="datePublished">Thu Dec 15 00:00:00 EST 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16243806"> <div itemprop="name">Lymphangiogenesis correlates with lymph node metastasis, prognosis, and angiogenic phenotype in human non-small cell lung cancer.</div> </a> <div itemprop="about">Clinical cancer research : an official journal of the American Association for Cancer Research</div> <div itemprop="author">Renyi-Vamos F,Tovari J,Fillinger J,Timar J,Paku S,Kenessey I,Ostoros G,Agocs L,Soltesz I,Dome B</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the correlation of lymphangiogenesis with lymph node metastasis, prognosis, and angiogenic phenotype in human non-small cell lung cancer</div> <div itemprodp="datePublished">Sat Oct 15 00:00:00 EDT 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/15805273"> <div itemprop="name">Broad-spectrum G protein-coupled receptor antagonist, [D-Arg1,D-Trp5,7,9,Leu11]SP: a dual inhibitor of growth and angiogenesis in pancreatic cancer.</div> </a> <div itemprop="about">Cancer research</div> <div itemprop="author">Guha S,Eibl G,Kisfalvi K,Fan RS,Burdick M,Reber H,Hines OJ,Strieter R,Rozengurt E</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of a broad-spectrum G protein-coupled receptor antagonist on growth and angiogenesis in pancreatic cancer</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EST 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/15870705"> <div itemprop="name">A germ line mutation that delays prostate cancer progression and prolongs survival in a murine prostate cancer model.</div> </a> <div itemprop="about">Oncogene</div> <div itemprop="author">Majeed N,Blouin MJ,Kaplan-Lefko PJ,Barry-Shaw J,Greenberg NM,Gaudreau P,Bismar TA,Pollak M</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of growth hormone-insulin-like growth factor-I pathway in prostate carcinogenesis and progression</div> <div itemprodp="datePublished">Thu Jul 07 00:00:00 EDT 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/15790973"> <div itemprop="name">The role of Axin2 in calvarial morphogenesis and craniosynostosis.</div> </a> <div itemprop="about">Development (Cambridge, England)</div> <div itemprop="author">Yu HM,Jerchow B,Sheu TJ,Liu B,Costantini F,Puzas JE,Birchmeier W,Hsu W</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role of Axin2 in calvarial morphogenesis and craniosynostosis</div> <div itemprodp="datePublished">Fri Apr 01 00:00:00 EST 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16177030"> <div itemprop="name">Transforming growth factor beta 1 promotes cell cycle exit through the cyclin-dependent kinase inhibitor p21 in the developing cerebral cortex.</div> </a> <div itemprop="about">The Journal of neuroscience : the official journal of the Society for Neuroscience</div> <div itemprop="author">Siegenthaler JA,Miller MW</div> <div itemprop="description">MA5-14520 was used in immunocytochemistry and immunohistochemistry to study the mechanism by which TGF-beta1 promotes cell cycle exit in the developing cerebral cortex</div> <div itemprodp="datePublished">Wed Sep 21 00:00:00 EDT 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/15917479"> <div itemprop="name">Characterization and localization of side population cells in mouse skin.</div> </a> <div itemprop="about">Stem cells (Dayton, Ohio)</div> <div itemprop="author">Yano S,Ito Y,Fujimoto M,Hamazaki TS,Tamaki K,Okochi H</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the role and localization of side population cells in mouse skin</div> <div itemprodp="datePublished">Fri Sep 16 00:00:00 EDT 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16190877"> <div itemprop="name">Ethanol disrupts cell cycle regulation in developing rat cortex interaction with transforming growth factor beta1.</div> </a> <div itemprop="about">Journal of neurochemistry</div> <div itemprop="author">Siegenthaler JA,Miller MW</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the effect of ethanol on normal cell proliferation and TGFbeta1-regulated cell proliferation in the developing cortex</div> <div itemprodp="datePublished">Tue Nov 01 00:00:00 EST 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/16012853"> <div itemprop="name">p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas.</div> </a> <div itemprop="about">Virchows Archiv : an international journal of pathology</div> <div itemprop="author">Matos I,Dufloth R,Alvarenga M,Zeferino LC,Schmitt F</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to study the diagnostic markers of basal breast carcinomas</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/15983117"> <div itemprop="name">Resin tissue microarrays: a universal format for immunohistochemistry.</div> </a> <div itemprop="about">The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society</div> <div itemprop="author">Howat WJ,Warford A,Mitchell JN,Clarke KF,Conquer JS,McCafferty J</div> <div itemprop="description">MA5-14520 was used in western blot to establish a tissue array platform for immunohistochemistry</div> <div itemprodp="datePublished">Sat Oct 01 00:00:00 EDT 2005</div> <a itemprop="sameAs" href="http://www.ncbi.nlm.nih.gov/pubmed/15964834"> <div itemprop="name">Hoxb13 up-regulates transglutaminase activity and drives terminal differentiation in an epidermal organotypic model.</div> </a> <div itemprop="about">The Journal of biological chemistry</div> <div itemprop="author">Mack JA,Li L,Sato N,Hascall VC,Maytin EV</div> <div itemprop="description">MA5-14520 was used in immunohistochemistry to investigate the role of Hoxb13 in epidermal differentiation</div> <div itemprodp="datePublished">Fri Aug 19 00:00:00 EDT 2005</div> </div> </noscript> </div> <div class="border-bottom"></div> <div class="product-bioinformatics-details"> <div class="container"> <h2 class="pdp-sub-heading">Bioinformatics</h2> <div class="row"> <div class="large-span-6 medium-span-12 small-span-12"> <div class="bioinformatics-wrapper"> <p class="bioinformatics-detail-section" id="proteinContent"> <strong>Protein Aliases:</strong> Antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2 </p> <p class="view-buttons" id="ptnViewBtn" ng-class="$ctrl.bioContentLines('proteinContent', 'ptnViewBtn')"> <a id="proteinViewMoreBtn" ng-click="$ctrl.bioContentViewMore('proteinViewMoreBtn', 'proteinViewLessBtn', 'proteinContent')"> View more </a> <a id="proteinViewLessBtn" ng-click="$ctrl.bioContentViewLess('proteinViewLessBtn', 'proteinViewMoreBtn', 'proteinContent')"> View less </a> </p> </div> <div class="bioinformatics-wrapper"> <p class="bioinformatics-detail-section" id="geneContent"> <strong>Gene Aliases:</strong> D630048A14Rik; Ki-67; Ki67; KIA; MIB-; MIB-1; MKI67; PPP1R105 </p> <p class="view-buttons" id="geneViewBtn" ng-class="$ctrl.bioContentLines('geneContent', 'geneViewBtn')"> <a id="geneViewMoreBtn" ng-click="$ctrl.bioContentViewMore('geneViewMoreBtn', 'geneViewLessBtn', 'geneContent')"> View more </a> <a id="geneViewLessBtn" ng-click="$ctrl.bioContentViewLess('geneViewLessBtn', 'geneViewMoreBtn', 'geneContent')"> View less </a> </p> </div> <div class="bioinformatics-wrapper"> <p class="bioinformatics-detail-section" id="unitProContent"> <strong>UniProt ID:</strong> <a href="http://www.uniprot.org/uniprot/P46013" target="_blank">(Human) P46013</a>, <a href="http://www.uniprot.org/uniprot/E9PVX6" target="_blank">(Mouse) E9PVX6</a> </p> <p class="view-buttons" id="unitViewBtn" ng-class="$ctrl.bioContentLines('unitProContent', 'unitViewBtn')"> <a id="unitProViewMoreBtn" ng-click="$ctrl.bioContentViewMore('unitProViewMoreBtn', 'unitProViewLessBtn', 'unitProContent')"> View more </a> <a id="unitProViewLessBtn" ng-click="$ctrl.bioContentViewLess('unitProViewLessBtn', 'unitProViewMoreBtn', 'unitProContent')"> View less </a> </p> </div> <div class="bioinformatics-wrapper"> <p class="bioinformatics-detail-section" id="entrezContent"> <strong>Entrez Gene ID:</strong> <a href="http://www.ncbi.nlm.nih.gov/gene?term=4288" target="_blank">(Human) 4288</a>, <a href="http://www.ncbi.nlm.nih.gov/gene?term=291234" target="_blank">(Rat) 291234</a>, <a href="http://www.ncbi.nlm.nih.gov/gene?term=17345" target="_blank">(Mouse) 17345</a> </p> <p class="view-buttons" id="etzViewBtn" ng-class="$ctrl.bioContentLines('entrezContent', 'etzViewBtn')"> <a id="entrezViewMoreBtn" ng-click="$ctrl.bioContentViewMore('entrezViewMoreBtn', 'entrezViewLessBtn', 'entrezContent')"> View more </a> <a id="entrezViewLessBtn" ng-click="$ctrl.bioContentViewLess('entrezViewLessBtn', 'entrezViewMoreBtn', 'entrezContent')"> View less </a> </p> </div> </div> <div class="large-span-6 medium-span-12 small-span-12"> <div class="accordion" id="accordion-bioinformatics"> <div class="accordion-group"> <div class="accordion-heading"> <a class="accordion-toggle" data-toggle="collapse" data-parent="#accordion2" target="_self" href="#collapseOne"> Function(s) </a> </div> <div id="collapseOne" class="accordion-body collapse"> <div class="accordion-inner"> <a class="icon" href="/antibody/primary/panther/protein binding"> protein binding </a> <a class="icon" href="/antibody/primary/panther/ATP binding"> ATP binding </a> <a class="icon" href="/antibody/primary/panther/protein C-terminus binding"> protein C-terminus binding </a> <a class="icon" href="/antibody/primary/panther/poly(A) RNA binding"> poly(A) RNA binding </a> <a class="icon" href="/antibody/primary/panther/molecular_function"> molecular_function </a> </div> </div> </div> <div class="accordion-group"> <div class="accordion-heading"> <a class="accordion-toggle" data-toggle="collapse" data-parent="#accordion2" target="_self" href="#collapseTwo"> Process(es) </a> </div> <div id="collapseTwo" class="accordion-body collapse"> <div class="accordion-inner"> <a class="icon" href="/antibody/primary/panther/DNA metabolic process"> DNA metabolic process </a> <a class="icon" href="/antibody/primary/panther/meiotic nuclear division"> meiotic nuclear division </a> <a class="icon" href="/antibody/primary/panther/cell proliferation"> cell proliferation </a> <a class="icon" href="/antibody/primary/panther/response to organic cyclic compound"> response to organic cyclic compound </a> <a class="icon" href="/antibody/primary/panther/hyaluronan metabolic process"> hyaluronan metabolic process </a> <a class="icon" href="/antibody/primary/panther/organ regeneration"> organ regeneration </a> <a class="icon" href="/antibody/primary/panther/cellular response to heat"> cellular response to heat </a> <a class="icon" href="/antibody/primary/panther/hepatocyte proliferation"> hepatocyte proliferation </a> <a class="icon" href="/antibody/primary/panther/cholangiocyte proliferation"> cholangiocyte proliferation </a> </div> </div> </div> </div> </div> </div> </div> </div> <div class="recommended-products border-bottom hidden">  It has to be done as per old AB suggested Products section. </div> <script type="text/javascript" src="/order/genome-database/assets/core/js/magellanCore.js?version=Local&time=20240917&build-time=2024-11-22T02:34:20+0000"></script> <script 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$m.addPerformanceMark('abPDPScripts:loadEnd'); $m.addPerformanceMeasure('abPDPScripts:loadTime' , 'abPDPScripts:loadBegin', 'abPDPScripts:loadEnd'); </script> </div> <script> if (typeof window.$mangular === 'undefined' || !window.$mangular) { window.$mangular = {}; } window.$mangular.referenceCount = 795; window.$mangular.publishedFiguresCount = 0; window.$mangular.productId = 'MA5-14520'; window.$mangular.citationJson = {"citationApplications":[{"applicationAbbreviation":"WB","citations":[{"title":"Progesterone, via yes-associated protein, promotes cardiomyocyte proliferation and cardiac repair.","summary":"MA5-14520 was used in Western Blotting to uncover a role of circulating progesterone withdrawal as a novel mechanism for the postnatal loss of mammalian cardiac regenerative potential.","authors":"Lan C,Cao N,Chen C,Qu S,Fan C,Luo H,Zeng A,Yu C,Xue Y,Ren H,Li L,Wang H,Jose PA,Xu Z,Zeng C","literatureId":"33047378","journal":"Cell proliferation","volume":"53","publishedDate":"Nov 1, 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