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MobileHeader_mobileIcon__tLrIo w-[17px] h-[13px] pr-1" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M80 48c-8.8 0-16 7.2-16 16V448c0 8.8 7.2 16 16 16H304c8.8 0 16-7.2 16-16V64c0-8.8-7.2-16-16-16H80zM16 64C16 28.7 44.7 0 80 0H304c35.3 0 64 28.7 64 64V448c0 35.3-28.7 64-64 64H80c-35.3 0-64-28.7-64-64V64zM160 400h64c8.8 0 16 7.2 16 16s-7.2 16-16 16H160c-8.8 0-16-7.2-16-16s7.2-16 16-16z"></path></svg>Use App</a><button class="MobileHeader_navMenuButton__521co MobileHeader_navButtonBase__w6cJF h-[50px] flex justify-center items-center cursor-pointer w-[35px]"><svg aria-hidden="true" focusable="false" data-prefix="fal" data-icon="magnifying-glass" class="svg-inline--fa fa-magnifying-glass " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M384 208A176 176 0 1 0 32 208a176 176 0 1 0 352 0zM343.3 366C307 397.2 259.7 416 208 416C93.1 416 0 322.9 0 208S93.1 0 208 0S416 93.1 416 208c0 51.7-18.8 99-50 135.3L507.3 484.7c6.2 6.2 6.2 16.4 0 22.6s-16.4 6.2-22.6 0L343.3 366z"></path></svg></button></div></nav><div class="MobileHeader_center__l_JVA absolute top-2/4 left-2/4 transform -translate-x-2/4 -translate-y-2/4 text-primary-text flex justify-center items-end cursor-pointer"><span class="absolute opacity-0 pointer-events-none">Stocktwits</span><a title="Stocktwits" class="MobileHeader_logoLink__1wldO block w-full h-full p-2" href="/"><svg width="100%" height="100%" viewBox="0 0 32 28" fill="none" xmlns="http://www.w3.org/2000/svg"><g clip-path="url(#clip0_8680_547)"><path fill-rule="evenodd" clip-rule="evenodd" d="M8.43835 0.374634H29.818V0.375255C31.4269 0.375255 32.333 1.62625 31.8327 3.15452L26.4417 19.6217C26.0621 20.7813 24.7526 21.7307 23.532 21.7307H17.8413L7.84361 27.9106L9.86606 21.7307H2.15224C0.54355 21.7307 -0.36256 20.4797 0.13772 18.9514L5.52869 2.48361C5.90831 1.32401 7.21782 0.374634 8.43835 0.374634ZM20.3165 2.59513L18.82 4.5743C17.9663 4.57338 17.2605 4.57175 16.7138 4.57048C16.5421 4.5701 16.386 4.56971 16.2461 4.56945C13.0738 4.56089 10.8185 7.35907 11.7039 9.81416C12.0889 11.1591 13.6515 11.7941 14.8779 12.2925L14.8964 12.2999C15.1545 12.4046 15.3971 12.503 15.6099 12.6013C16.1784 12.8481 15.9633 13.6945 15.3424 13.6982C14.2449 13.7085 8.19588 13.7311 8.19588 13.7311L5.4818 17.3202H9.2007L7.70839 19.2933H11.4273L12.9196 17.3202H13.1469C13.4144 17.3214 13.691 17.3281 13.9738 17.3354C15.4795 17.3732 17.1339 17.414 18.2636 16.673C20.1472 15.5853 20.7169 13.6921 20.2672 12.0761H20.2666C19.8816 10.7305 18.319 10.0955 17.0926 9.59715L17.0604 9.58409C16.8081 9.48152 16.5703 9.3849 16.3612 9.28828C15.7927 9.04086 16.0078 8.19569 16.6287 8.19143C17.7262 8.18107 23.7752 8.15854 23.7752 8.15854L26.4893 4.56945C25.0463 4.57247 23.7265 4.5743 22.5389 4.57492L24.0366 2.59513H20.3165Z" fill="currentColor"></path></g><defs><clipPath id="clip0_8680_547"><rect width="32" height="28" fill="white"></rect></clipPath></defs></svg></a></div></div></div><div class="MainHeader_desktopHeaderContainer__sKsDd hidden tabletMd|block border-primary-hairline border-b"><div class="DesktopHeader_container__4nFE3 flex flex-row justify-between items-center h-[50px] gap-x-5 tabletXxl|gap-x-8 px-5 max-w-[1340px]"><div class="w-full"><div class="DesktopHeader_search__9FdhP relative z-10 w-full max-w-[400px] min-w-[360px] DesktopHeader_transition__0b3LE transition-all duration-150 ease-in-out"></div></div><div class="DesktopHeader_nav___J3Kw flex flex-row justify-end items-center"><ul class="SiteNav_navbar__LXGWZ flex flex-row justify-end gap-x-[32px]"><li class="SiteNav_navbarLink__dEMWl SiteNav_link__n2uAf items-center text-primary-text inline-flex justify-between tabletMd-down|mr-5 tabletMd-down|border-b tabletMd-down|border-sitenav-border SiteNav_linkWithFontSize__K1HuW text-[13px]" data-testid="markets-site-nav-link"><a class="SiteNav_linkText__Bgfr8 tabletSm|text-right block" href="/sentiment">Trending</a></li><li class="SiteNav_navbarLink__dEMWl SiteNav_link__n2uAf items-center text-primary-text inline-flex justify-between tabletMd-down|mr-5 tabletMd-down|border-b tabletMd-down|border-sitenav-border SiteNav_linkWithFontSize__K1HuW text-[13px]"><a class="SiteNav_linkText__Bgfr8 tabletSm|text-right block" href="/news-articles">News</a></li><li class="SiteNav_navbarLink__dEMWl SiteNav_link__n2uAf items-center text-primary-text inline-flex justify-between tabletMd-down|mr-5 tabletMd-down|border-b tabletMd-down|border-sitenav-border SiteNav_linkWithFontSize__K1HuW text-[13px]"><a class="SiteNav_linkText__Bgfr8 tabletSm|text-right block" href="/sentiment/calendar">Earnings</a></li><li class="SiteNav_navbarLink__dEMWl SiteNav_link__n2uAf items-center text-primary-text inline-flex justify-between tabletMd-down|mr-5 tabletMd-down|border-b tabletMd-down|border-sitenav-border SiteNav_linkWithFontSize__K1HuW text-[13px]"><a class="SiteNav_linkText__Bgfr8 tabletSm|text-right block" target="_blank" href="https://www.stocktwits.com/newsletters">Newsletters</a></li><li class="SiteNav_navbarLink__dEMWl SiteNav_link__n2uAf items-center text-primary-text inline-flex justify-between tabletMd-down|mr-5 tabletMd-down|border-b tabletMd-down|border-sitenav-border SiteNav_linkWithFontSize__K1HuW text-[13px]"><a class="SiteNav_linkText__Bgfr8 tabletSm|text-right block" target="_blank" href="https://stocktwits.com/about/contact/?subject=Advertising%20Inquiries">Advertise</a></li></ul></div></div></div><div class="MainHeader_secondaryHeaderContainer__G0oQ4 border-t-0"><div class="Trending_containerThin__lOpNq Trending_container__6jqOE flex items-center justify-between overflow-hidden whitespace-nowrap font-semibold text-xs tabletSm|py-2.5 py-2.5" data-testid="trending-view"><div class="whitespace-pre-wrap"></div><div class="Trending_indicesShort__K_CXM flex flex-row items-center justify-between tabletSm|justify-between pl-5 pr-4 tabletSm-down|uppercase tabletSm-down|grow Trending_indicesShortUS__nOSfR w-[260px] Trending_disabledMarquee__6ilIf"><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/DIA"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">DIA</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">0.90%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/SPY"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">SPY</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">0.89%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/QQQ"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">QQQ</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">1.24%</span></span></span></div></a></div><div class="Trending_trending__DXWES tabletSm-down|flex w-full flex-row grow-[2] gap-x-[15px] pr-6 border-l border-primary-hairline contents tabletSm-down|hidden"><div class="flex flex-row justify-between items-center mr-2"><div class="Trending_trendingLabel__2JYHk tabletSm-down|hidden uppercase tabletSm|flex items-center Trending_updatedTrendingLabel__nZod8 text-[9px]"><span>Trending</span><svg aria-hidden="true" focusable="false" data-prefix="far" data-icon="circle-info" class="svg-inline--fa fa-circle-info Disclosures_icon__sUHXX ml-1 cursor-pointer !text-[12px]" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M256 48a208 208 0 1 1 0 416 208 208 0 1 1 0-416zm0 464A256 256 0 1 0 256 0a256 256 0 1 0 0 512zM216 336c-13.3 0-24 10.7-24 24s10.7 24 24 24h80c13.3 0 24-10.7 24-24s-10.7-24-24-24h-8V248c0-13.3-10.7-24-24-24H216c-13.3 0-24 10.7-24 24s10.7 24 24 24h24v64H216zm40-144a32 32 0 1 0 0-64 32 32 0 1 0 0 64z"></path></svg></div></div><div class="flex"><div class="Trending_tickers__QRjxC flex mr-2 Trending_disabledMarquee__6ilIf"><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/QBTS"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><img alt="Top trending ticker" class="inline" height="12" src="https://chunks-prd.stocktwits-cdn.com/_next/static/media/hot.d13a6f1f.svg" width="10"/><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">QBTS</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-up-long" class="svg-inline--fa fa-arrow-up-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M214.6 9.4c-12.5-12.5-32.8-12.5-45.3 0l-128 128c-12.5 12.5-12.5 32.8 0 45.3s32.8 12.5 45.3 0L160 109.3V480c0 17.7 14.3 32 32 32s32-14.3 32-32V109.3l73.4 73.4c12.5 12.5 32.8 12.5 45.3 0s12.5-32.8 0-45.3l-128-128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">20.75%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/AAL"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">AAL</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">1.91%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/GLD"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">GLD</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-up-long" class="svg-inline--fa fa-arrow-up-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M214.6 9.4c-12.5-12.5-32.8-12.5-45.3 0l-128 128c-12.5 12.5-12.5 32.8 0 45.3s32.8 12.5 45.3 0L160 109.3V480c0 17.7 14.3 32 32 32s32-14.3 32-32V109.3l73.4 73.4c12.5 12.5 32.8 12.5 45.3 0s12.5-32.8 0-45.3l-128-128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">1.89%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/FNMA"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">FNMA</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">2.65%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/AAOI"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">AAOI</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-up-long" class="svg-inline--fa fa-arrow-up-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M214.6 9.4c-12.5-12.5-32.8-12.5-45.3 0l-128 128c-12.5 12.5-12.5 32.8 0 45.3s32.8 12.5 45.3 0L160 109.3V480c0 17.7 14.3 32 32 32s32-14.3 32-32V109.3l73.4 73.4c12.5 12.5 32.8 12.5 45.3 0s12.5-32.8 0-45.3l-128-128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">39.18%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/ALT"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">ALT</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">5.92%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/ULTA"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">ULTA</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-up-long" class="svg-inline--fa fa-arrow-up-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M214.6 9.4c-12.5-12.5-32.8-12.5-45.3 0l-128 128c-12.5 12.5-12.5 32.8 0 45.3s32.8 12.5 45.3 0L160 109.3V480c0 17.7 14.3 32 32 32s32-14.3 32-32V109.3l73.4 73.4c12.5 12.5 32.8 12.5 45.3 0s12.5-32.8 0-45.3l-128-128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">1.92%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/ADBE"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">ADBE</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">13.78%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/AAPL"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">AAPL</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">3.12%</span></span></span></div></a><a class="Trending_ticker__j67AD pl-[11px] first|pl-0 first|mr-2" href="/symbol/DOCU"><div class="Trending_tickerLabel__4iKnb flex gap-x-1 text-primary-text"><span class="Trending_tickerName__Qgolo tabletMd-down|inline-block tabletMd-down|mr-0.25">DOCU</span><span class="Trending_tickerChange__n6QUj block h-[16px]"><span class="Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green" aria-label="Change"><span class="Change_arrow__AjLH9 relative flex items-center Change_positive__2H4d1 Change_container__GNa_f inline-flex gap-1 text-green text-[9px]" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-up-long" class="svg-inline--fa fa-arrow-up-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M214.6 9.4c-12.5-12.5-32.8-12.5-45.3 0l-128 128c-12.5 12.5-12.5 32.8 0 45.3s32.8 12.5 45.3 0L160 109.3V480c0 17.7 14.3 32 32 32s32-14.3 32-32V109.3l73.4 73.4c12.5 12.5 32.8 12.5 45.3 0s12.5-32.8 0-45.3l-128-128z"></path></svg></span><span class="Change_amount__l5O_n whitespace-nowrap" aria-label="Change">5.13%</span></span></span></div></a></div></div><div class="mr-2"><a class="Trending_more__C6Qly tabletSm-down|hidden flex font-normal items-center gap-1 bg-primary-background text-primary-text" data-testid="trending-view-more-button" href="/sentiment/trending">More<svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="chevron-right" class="svg-inline--fa fa-chevron-right Trending_moreIcon__D_foA tabletSm-down|hidden text-primary-text text-xxs" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 320 512"><path fill="currentColor" d="M310.6 233.4c12.5 12.5 12.5 32.8 0 45.3l-192 192c-12.5 12.5-32.8 12.5-45.3 0s-12.5-32.8 0-45.3L242.7 256 73.4 86.6c-12.5-12.5-12.5-32.8 0-45.3s32.8-12.5 45.3 0l192 192z"></path></svg></a></div></div></div></div></div><div class="Body_container__f_XJ0 flex flex-column desktopXxl|pr-0 Body_containerBorder__3T8GJ border-primary-hairline border-l tabletSm-down|border-x-0"><div class="Body_content__07Yri w-full max-w-[980px] tabletMd-down|max-w-none"><div class="SymbolPage_container__tRK07 tabletMd|max-w-[970px] w-full grid gap-2.5"><div class="SymbolPage_symbolPageBorder__gg8Gr border-primary-hairline border-r"><div class="SymbolPageHero_container__P6ghF mb-2.5 tabletSm-down|mb-0 tabletSm|p-2.5 tabletMd|p-0 tabletMd|mb-2.5 tabletMd|max-w-[660px]"><div></div><div class="Pod_container__AI83J bg-primary-background text-primary-text rounded-md"><div class="flex flex-row justify-start items-center Breadcrumbs_breadcrumbs__Rczip gap-2 tabletSm-down|gap-1 tabletSm-down|text-xxs h-8 px-4 tabletSm|px-5 text-st-tertiary-text text-xs w-full border-primary-hairline border-b whitespace-nowrap overflow-x-auto scrollbar-hidden"><a href="/"><span class="Breadcrumbs_breadcrumbsLink__sisdv hover|underline hover|text-st-primary-text cursor-pointer capitalize shrink-0">home</span></a><svg aria-hidden="true" focusable="false" data-prefix="far" data-icon="chevron-right" class="svg-inline--fa fa-chevron-right fa-sm Breadcrumbs_chevronRight__Ifb18 mx-1 pt-[1px]" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 320 512"><path fill="currentColor" d="M305 239c9.4 9.4 9.4 24.6 0 33.9L113 465c-9.4 9.4-24.6 9.4-33.9 0s-9.4-24.6 0-33.9l175-175L79 81c-9.4-9.4-9.4-24.6 0-33.9s24.6-9.4 33.9 0L305 239z"></path></svg><a href="/symbol"><span class="Breadcrumbs_breadcrumbsLink__sisdv hover|underline hover|text-st-primary-text cursor-pointer capitalize shrink-0">Symbol</span></a><svg aria-hidden="true" focusable="false" data-prefix="far" data-icon="chevron-right" class="svg-inline--fa fa-chevron-right fa-sm Breadcrumbs_chevronRight__Ifb18 mx-1 pt-[1px]" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 320 512"><path fill="currentColor" d="M305 239c9.4 9.4 9.4 24.6 0 33.9L113 465c-9.4 9.4-24.6 9.4-33.9 0s-9.4-24.6 0-33.9l175-175L79 81c-9.4-9.4-9.4-24.6 0-33.9s24.6-9.4 33.9 0L305 239z"></path></svg><span class="capitalize">ANVS</span></div><div class="SymbolPageHero_head__SRDI5 SymbolPageHero_grid__xbZvk grid tabletSm|px-5 tabletSm|py-2"><div class="SymbolPageHero_lede__LS_6R"><div class="SymbolInfo_container__wI07q flex flex-col"><div class="SymbolInfo_content__n_HwR"><div class="SymbolInfo_info__AFfk4 flex justify-between tabletMd|items-center tabletSm-down|px-4"><div class="SymbolLede_container__tlm6Y w-full flex flex-row items-center justify-between pb-2"><h1><div class="flex flex-row justify-start items-center gap-x-2 py-0.5"><span class="SymbolLede_label__SmBPZ block font-bold !text-[17px] leading-[22px] tabletSm-down|pt-2" data-testid="symbol-text">ANVS </span></div><span class="SymbolLede_title__O8aWL block text-tertiary-text text-xs font-normal tabletSm-down|max-w-[200px]">Annovis Bio Inc</span></h1><div class="SymbolLede_buttons__frYVl flex flex-row gap-2 items-center tabletMd-down|mt-2.5"><div class="SymbolLede_watch__R83q9 flex"><div class="SymbolWatchers_container__5vi3I flex items-center gap-3"><span class="SymbolWatchers_watchers__sp1FU tabletSm-down|hidden inline-flex gap-1.5 items-center text-xs"><svg fill="none" height="100%" viewBox="0 0 12 12" width="100%" xmlns="http://www.w3.org/2000/svg" class="SymbolWatchers_icon__w3PFN w-[10px] h-[10px]"><circle cx="6" cy="3" r="2" stroke="currentcolor"></circle><path d="M1 11.5C1.62805 9.18934 3.62886 7.5 6 7.5C8.37114 7.5 10.3719 9.18934 11 11.5" stroke="currentcolor"></path></svg>9,722</span></div></div></div></div></div><div class="SymbolInfo_pricing__UbjwC pt-1 border-t border-primary-hairline flex justify-between items-center relative"></div><div class="SymbolInfo_pricing__UbjwC pt-1 border-t border-primary-hairline flex justify-between items-center relative border-none"><div class="SymbolPricing_container__7FqjG relative flex flex-row justify-between items-center w-full tabletSm|w-auto tabletSm-down|px-4"><div class="SymbolPricing_priceContainer__6OFmu"><div class="SymbolPricing_amountContainer__Hx2b0 flex flex-col gap-x-2"><div class="SymbolPricing_updatedAmountFont__3N7up text-[35px] font-normal SymbolPricing_amount__UX8jT text-[35px] leading-10 font-light mb-1 h-[36px]">$1.65</div><div class="SymbolPricing_changeContainer__lBLyv text-[13px] flex flex-row gap-x-1 mb-1 h-[17px] leading-[17px]"><span class="SymbolPricing_change__DzzzZ whitespace-nowrap"><span class="Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" aria-label="Change"><div class="flex flex-row justify-between items-end gap-0.5"><div class="flex flex-row justify-between items-center gap-1"><span class="Change_arrow__AjLH9 relative flex items-center Change_negative__3Cz_W Change_container__GNa_f inline-flex gap-1 text-red" role="presentation"><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="arrow-down-long" class="svg-inline--fa fa-arrow-down-long " role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 384 512"><path fill="currentColor" d="M169.4 502.6c12.5 12.5 32.8 12.5 45.3 0l128-128c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L224 402.7 224 32c0-17.7-14.3-32-32-32s-32 14.3-32 32l0 370.7L86.6 329.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l128 128z"></path></svg></span><span data-testid="stock-price-change">$0.05</span></div><div class="flex flex-row justify-between items-center gap-1"><span data-testid="stock-price-percent-change"> (2.94%)</span></div></div></span></span><span>Today</span></div></div></div><div><table class="SymbolPricingFundamentals_container__a5E1m text-xs text-dark-grey flex flex-col tabletSm|hidden"><tbody><tr class="SymbolPricingFundamentals_row__eVoxP flex justify-between"><td class="SymbolPricingFundamentals_title__ojEt4 mr-2">Watchers</td><td>9,722</td></tr></tbody></table></div></div></div></div></div></div></div><div class="flex flex-col justify-between items-center cursor-pointer FundamentalsDataSummary_container__riWEH mt-4 mx-5 px-4 tabletSm-down|mx-4 tabletSm-down|px-4 py-2 mb-4 border border-primary-border rounded-lg FundamentalsDataSummary_hoverState__sUhGl hover|bg-light-grey-6-rgba-50 dark|hover|bg-dark-grey-5 cursor-pointer"><div class="flex flex-row justify-between items-center w-full"><div class="flex flex-row justify-around items-center w-full"><div><div class="flex flex-col justify-between items-center"><span class="FundamentalsDataSummary_itemTitle__Z1vQw text-xs text-st-secondary-text">Mkt Cap</span><span class="FundamentalsDataSummary_itemValue__NfAfA text-sm">$32.15M</span></div></div><div><div class="flex flex-col justify-between items-center"><span class="FundamentalsDataSummary_itemTitle__Z1vQw text-xs text-st-secondary-text">Volume</span><span class="FundamentalsDataSummary_itemValue__NfAfA text-sm">163,000.00</span></div></div><div><div class="flex flex-col justify-between items-center"><span class="FundamentalsDataSummary_itemTitle__Z1vQw text-xs text-st-secondary-text">52W High</span><span class="FundamentalsDataSummary_itemValue__NfAfA text-sm">$20.00</span></div></div><div><div class="flex flex-col justify-between items-center"><span class="FundamentalsDataSummary_itemTitle__Z1vQw text-xs text-st-secondary-text">52W Low</span><span class="FundamentalsDataSummary_itemValue__NfAfA text-sm">$1.53</span></div></div><div class="tabletSm-down|hidden"><div class="flex flex-col justify-between items-center"><span class="FundamentalsDataSummary_itemTitle__Z1vQw text-xs text-st-secondary-text">PE Ratio</span><span class="FundamentalsDataSummary_itemValue__NfAfA text-sm">-0.43</span></div></div></div><svg aria-hidden="true" focusable="false" data-prefix="fas" data-icon="chevron-down" class="svg-inline--fa fa-chevron-down FundamentalsDataSummary_chevron__jnhnT w-[12px] ml-5" role="img" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 512 512"><path fill="currentColor" d="M233.4 406.6c12.5 12.5 32.8 12.5 45.3 0l192-192c12.5-12.5 12.5-32.8 0-45.3s-32.8-12.5-45.3 0L256 338.7 86.6 169.4c-12.5-12.5-32.8-12.5-45.3 0s-12.5 32.8 0 45.3l192 192z"></path></svg></div></div><div><div><div id="symbol-page-hero-tabs" class="react-tabs__tab-list Tab_reactTabList__DlGgm border-t !h-10 border-primary-hairline text-tertiary-text SymbolPageHero_symbolPageHeroTabs__s3VCs justify-around bg-legacy-white-four dark|bg-tertiary-background"><div data-cy="about-tab" class="react-tabs__tab Tab_reactTab__AN_bb relative border-b-2 border-transparent bg-primary-background SymbolPageHero_tab___OATW !bg-emphasized-tab-background SymbolPageHero_tab-about__lvD4w"><div class="SymbolPageHero_noPadding__dFwEA"><a href="/symbol/ANVS/about" class="Tab_text__yKwPe text-sm font-semibold"><h2 class="SymbolPageHero_label__pWp6i font-semibold text-[13px] h-[17px] leading-[17px]">About</h2></a></div></div><span></span><div data-cy="feed-tab" class="react-tabs__tab Tab_reactTab__AN_bb relative border-b-2 border-transparent bg-primary-background SymbolPageHero_tab___OATW !bg-emphasized-tab-background SymbolPageHero_tab-feed__TPjt2"><div class="SymbolPageHero_noPadding__dFwEA"><a href="/symbol/ANVS" class="Tab_text__yKwPe text-sm font-semibold"><h2 class="SymbolPageHero_label__pWp6i font-semibold text-[13px] h-[17px] leading-[17px]">Feed</h2></a></div></div><span></span><div data-cy="news-tab" class="react-tabs__tab Tab_reactTab__AN_bb relative border-b-2 border-transparent bg-primary-background SymbolPageHero_tab___OATW !bg-emphasized-tab-background SymbolPageHero_tab-news__2_yPc"><div class="SymbolPageHero_noPadding__dFwEA"><a href="/symbol/ANVS/news" class="Tab_text__yKwPe text-sm font-semibold"><h2 class="SymbolPageHero_label__pWp6i font-semibold text-[13px] h-[17px] leading-[17px]">News</h2></a></div></div><span></span><div data-cy="sentiment-tab" class="react-tabs__tab Tab_reactTab__AN_bb relative border-b-2 border-transparent bg-primary-background SymbolPageHero_tab___OATW !bg-emphasized-tab-background SymbolPageHero_tab-sentiment__rTL7t"><div class="SymbolPageHero_noPadding__dFwEA"><a href="/symbol/ANVS/sentiment" class="Tab_text__yKwPe text-sm font-semibold"><h2 class="SymbolPageHero_label__pWp6i font-semibold text-[13px] h-[17px] leading-[17px]">Sentiment</h2></a></div></div><span></span><div data-cy="earnings-tab" class="react-tabs__tab Tab_reactTab__AN_bb relative border-b-2 border-transparent bg-primary-background SymbolPageHero_tab___OATW !bg-emphasized-tab-background SymbolPageHero_tab-earnings__XxMb3"><div class="SymbolPageHero_noPadding__dFwEA"><a href="/symbol/ANVS/earnings" class="Tab_text__yKwPe text-sm font-semibold"><h2 class="SymbolPageHero_label__pWp6i font-semibold text-[13px] h-[17px] leading-[17px]">Earnings</h2></a></div></div><span></span><div data-cy="fundamentals-tab" class="react-tabs__tab Tab_reactTab__AN_bb relative border-b-2 border-transparent bg-primary-background SymbolPageHero_tab___OATW !bg-emphasized-tab-background SymbolPageHero_tab-fundamentals__n0pH9"><div class="SymbolPageHero_noPadding__dFwEA"><a href="/symbol/ANVS/fundamentals" class="Tab_text__yKwPe text-sm font-semibold"><h2 class="SymbolPageHero_label__pWp6i font-semibold text-[13px] h-[17px] leading-[17px]">Fundamentals</h2></a></div></div><span></span></div><div><div class="SymbolPageHero_tabContent__OXeMQ hidden SymbolPageHero_aboutContent__rfdc4"></div><div class="SymbolPageHero_tabContent__OXeMQ hidden SymbolPageHero_feedContent__hrN9a"><div class="SymbolPageHero_fullViewContainer__4dxkj SymbolPageHero_mediaContainer__ht6Wg grid min-h-[304px]" data-cy="symbol-page-hero-media"><script id="table-schema" type="application/ld+json">{ "@context": "https://schema.org", "@type": "Table", "about": "ANVS Fundamentals" }</script><span itemscope="" itemType="https://schema.org/DataFeed"><meta itemProp="name" content="Annovis Bio Inc (ANVS) Stock Price Today, Quote, Latest Discussions, Interactive Chart and News"/><meta itemProp="description" content="Track Annovis Bio Inc (ANVS) Stock Price, Quote, latest community messages, chart, news and other stock related information. 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class='cancel'\u003e\u003ca href='https://www.etoro.com/markets/ANVS?utm_medium=Media%20Performance\u0026amp;utm_source=122986\u0026amp;utm_content=21403\u0026amp;st-action=cancel'\u003e\u003csvg fill='none' height='15' viewBox='0 0 14 15' width='14' xmlns='http://www.w3.org/2000/svg'\u003e\u003cpath d='M13.5742 2.63672L8.41797 7.79297L13.5312 12.9062C13.9609 13.293 13.9609 13.9375 13.5312 14.3242C13.1445 14.7539 12.5 14.7539 12.1133 14.3242L6.95703 9.21094L1.84375 14.3242C1.45703 14.7539 0.8125 14.7539 0.425781 14.3242C-0.00390625 13.9375 -0.00390625 13.293 0.425781 12.8633L5.53906 7.75L0.425781 2.63672C-0.00390625 2.25 -0.00390625 1.60547 0.425781 1.17578C0.8125 0.789062 1.45703 0.789062 1.88672 1.17578L7 6.33203L12.1133 1.21875C12.5 0.789062 13.1445 0.789062 13.5742 1.21875C13.9609 1.60547 13.9609 2.25 13.5742 2.63672Z' fill='#636366'\u003e\u003c/path\u003e\u003c/svg\u003e\u003c/a\u003e\u003c/div\u003e\u003cdiv class='header_image'\u003e\u003cimg alt='eToro logo' src='https://logos.stocktwits-cdn.com/etoro-logo-3x.png'\u003e\u003c/div\u003e\u003ch2\u003eTrade ANVS with eToro\u003c/h2\u003e\u003cp\u003eInvest with confidence on this and other assets through our partnership with eToro\u003c/p\u003e\u003cdiv class='center_image'\u003e\u003cimg alt='Trade with eToro candlestick chart' src='https://logos.stocktwits-cdn.com/etoro-modal-graphic-2x.png'\u003e\u003c/div\u003e\u003ca href='https://www.etoro.com/markets/ANVS?utm_medium=Media%20Performance\u0026amp;utm_source=122986\u0026amp;utm_content=21403\u0026amp;st-action=continue' id='trade_partnership_continue_btn' target='_blank'\u003eContinue to eToro\u003c/a\u003e\u003cp class='footer'\u003eFor illustration purposes only.\nYour capital is at 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platform company, which engages in the development of drugs which aim to treat neurodegenerative diseases such as Alzheimer's (AD) and Parkinson's (PD). Its lead product candidate, Buntanetap, is designed to address AD, PD, and potentially other chronic neurodegenerative diseases. Its product pipeline also includes ANVS405 and ANVS301, which focus on the treatment of traumatic brain injury, stroke, and advanced AD. The company was founded by Maria Luisa Maccecchini in May 2008 and is headquartered in Malvern, PA.","sectorName":"Health Technology","50DayMovingAverage":"3.4448","dividendRate":"0","pEGRatio":"","totalCash":"5.75472","dividendYieldSecurity":"0","revenueToAssets":"0","lastUpdated":"03/13/2025","revenuePerEmployee":"0","sharesOutstanding":"10.519933","averageDailyVolumeLast3Months":"519744.8814"},"quote":{"previousCloseDate":"2025-03-12","dateTime":"2025-03-13 16:00:00","uTCOffset":"-4","low":1.61,"extendedHoursPercentChange":4.242,"extendedHoursDateTime":"2025-03-13 19:09:42","type":"equity","outcome":"Success","extendedHoursPrice":1.72,"easternDateTime":"03/13/2025, 12:00:00 PM EDT","easternExtendedHoursDateTime":"03/13/2025, 03:09:42 PM EDT","symbol":"ANVS","previousClose":1.7,"volume":163000,"lastSize":"1755","percentChange":-2.941,"change":-0.05,"last":1.65,"extendedHoursType":"PostMarket","iSO8601":"2025-03-13T20:00:00Z","high":1.7299,"extendedHoursChange":0.07,"message":"Delay times are 15 mins for NYSE.","open":1.69},"articles":[{"author":{"description":"Ramakrishnan is a senior writer at Stocktwits, the largest social network for investors and traders. He specializes in covering the US markets and writes extensively on stocks, commodities, ETFs, and other asset classes, with a soft spot for EV companies and Big Tech.","designation":"Senior Staff Writer","id":3,"name":"Ramakrishnan M","profile_avatar":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/ram_author_image_resized_and_compressed_1_0022abb723.jpg","profile_link":"","social_media_links":{"facebook":"https://in.linkedin.com/in/ramakrishnan-m","twitter":"https://x.com/heyram27?lang=en","website":"https://stocktwits.com/BangaloreBidder"},"type":"Stocktwits"},"canonical_url":"","category":{"id":2,"name":"Markets"},"content":"\u003cp\u003eAnnovis Bio Inc.\u0026nbsp;shares saw heightened volatility early Tuesday after the FDA approved the final protocol for its pivotal Phase 3 Alzheimer’s disease (AD) study, grabbing significant attention among retail investors.\u0026nbsp;\u003c/p\u003e\u003cp\u003eThe revised protocol combines a six-month symptomatic evaluation with a 12-month disease-modifying assessment into a single trial, slated to start in January.\u003c/p\u003e\u003cp\u003eIn October 2024, Annovis secured FDA clearance to advance its late-stage studies based on promising Phase 2/3 data showing cognitive improvements in early-stage AD patients.\u0026nbsp;\u003c/p\u003e\u003cp\u003eAccording to CEO Maria Maccecchini, the new streamlined design allows for an accelerated timeline while maintaining scientific rigor, potentially enabling a New Drug Application (NDA) filing based on the six-month data while continuing to gather long-term results.\u003c/p\u003e\u003cp\u003eOn Stocktwits, retail sentiment for Annovis turned ‘extremely bullish,’ driving the ticker to the top of the platform’s trending tab.\u0026nbsp;\u003c/p\u003e\u003cp\u003eA bullish user predicted that, in a year, investors would regret not buying Annovis stock at its current price.\u003c/p\u003e\u003cp\u003e\u003cstembedurl\u003ehttps://stocktwits.com/stockpro27/message/599105236\u003c/stembedurl\u003e\u003c/p\u003e\u003cp\u003eAnother speculated there might be some major financing news based on the latest update.\u003c/p\u003e\u003cp\u003e\u003cstembedurl\u003ehttps://stocktwits.com/Pasakorius/message/599096373\u003c/stembedurl\u003e\u003c/p\u003e\u003cp\u003eAs of November 2024, Annovis had $13.6 million in cash, which the company had said was enough to prepare for and enter the Phase 3 study.\u003c/p\u003e\u003cp\u003eOne analyst earlier\u0026nbsp;\u003ca href=\"https://stocktwits.com/news-articles/markets/equity/anvs-stock-jumps-after-analyst-reiterates-buy/cJczO3TRI2\"\u003especulated\u003c/a\u003e the stock could surge to $30, more than a six-fold jump from current levels, if an NDA is successfully filed.\u003c/p\u003e\u003cp\u003eBuntanetap, Annovis’ experimental drug, takes a multi-target approach to address toxic proteins like amyloid, tau, and alpha-synuclein, offering hope as a comprehensive treatment for neurodegenerative diseases, including AD and Parkinson’s.\u003c/p\u003e\u003cp\u003eDespite losing 67% of its value in 2024, Annovis’ latest update has reignited investor interest, with analysts suggesting significant upside potential tied to the drug’s success.\u0026nbsp;\u003c/p\u003e\u003cp\u003eThe company now faces a pivotal year as it advances its mission to develop a groundbreaking treatment for neurodegenerative diseases.\u003c/p\u003e\u003cp\u003e\u003ci\u003eFor updates and corrections, email newsroom[at]stocktwits[dot]com.\u003c/i\u003e\u003c/p\u003e","created_at":"2025-01-07T15:07:05Z","featured_image":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/alzheimers_illustration_resized_d887704099.jpg","featured_image_attributes":{"alt_text":"Buntanetap, Annovis’ experimental drug, takes a multi-target approach to address toxic proteins like amyloid, tau, and alpha-synuclein. | Image source: Getty Images ","caption":"Buntanetap, Annovis’ experimental drug, takes a multi-target approach to address toxic proteins like amyloid, tau, and alpha-synuclein. | Image source: Getty Images ","url":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/alzheimers_illustration_resized_d887704099.jpg"},"headline":"Annovis Bio Stock Among Retail's Top Draws After FDA Nod For Final Phase 3 Alzheimer’s Study Protocol","image_url":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/alzheimers_illustration_resized_d887704099.jpg","meta_description":"According to CEO Maria Maccecchini, the new streamlined design potentially enables a New Drug Application filing based on the six-month data.","meta_keywords":"Annovis Bio stock surge, Annovis Bio FDA approval, Alzheimer’s Phase 3 study, AD clinical trials, Buntanetap, Alzheimer’s drug","meta_title":"Annovis Bio Stock Among Retail's Top Draws After FDA Nod For Final Phase 3 Alzheimer’s Study Protocol","primary_symbol_code":"ANVS","sid":"chGI54YRm8","source":{"id":1071,"source_name":"Stocktwits","url_domain":"stocktwits.com"},"subcategory":{"id":3,"name":"Equity","parent_id":2},"summary":"According to CEO Maria Maccecchini, the new streamlined design potentially enables a New Drug Application filing based on the six-month data.","symbol_codes":["ANVS","VTI","VXF","IWC"],"tags":[{"id":2,"tag_name":"Trending"},{"id":3,"tag_name":"Small Cap"},{"id":10,"tag_name":"Retail"}],"type":"article","updated_at":"2025-01-07T15:07:05Z","url_slug":"anvs-stock-rises-as-fda-okays-final-alzheimers-study-protocol"},{"author":{"description":"Ramakrishnan is a senior writer at Stocktwits, the largest social network for investors and traders. He specializes in covering the US markets and writes extensively on stocks, commodities, ETFs, and other asset classes, with a soft spot for EV companies and Big Tech.","designation":"Senior Staff Writer","id":3,"name":"Ramakrishnan M","profile_avatar":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/ram_author_image_resized_and_compressed_1_0022abb723.jpg","profile_link":"","social_media_links":{"facebook":"https://in.linkedin.com/in/ramakrishnan-m","twitter":"https://x.com/heyram27?lang=en","website":"https://stocktwits.com/BangaloreBidder"},"type":"Stocktwits"},"canonical_url":"","category":{"id":2,"name":"Markets"},"content":"\u003cp\u003eShares of Annovis Bio, Inc. (\u003ca class=\"mention\" data-mention=\"$ANVS\" data-symbol-id=\"ANVS\" href=\"https://stocktwits.com/symbol/ANVS\" target=\"_blank\"\u003e$ANVS\u003c/a\u003e) surged more than 17% on Wednesday following an analyst’s reiteration of a ‘Buy’ rating and a $30 price target, which represents an upside of over 200% from current levels.\u003c/p\u003e\u003cp\u003eH.C. Wainwright analyst Ram Selvaraju based his bullish outlook on the advancement of Annovis Bio’s lead Alzheimer’s drug candidate, buntanetap.\u003c/p\u003e\u003cp\u003eThe FDA recently granted clearance for the company to proceed to Phase 3 trials, following successful Phase 2 results that showed improvement in Alzheimer’s patients.\u003c/p\u003e\u003cp\u003eThe analyst highlighted this regulatory clarity as a critical milestone, adding that the lack of safety concerns around the drug further reduces development risks.\u003c/p\u003e\u003cp\u003eSelvaraju also noted that if Annovis successfully files New Drug Applications (NDAs) for buntanetap, it could dramatically increase the company’s valuation. His $30 price target is supported by a discounted cash flow analysis.\u003c/p\u003e\u003cfigure class=\"image\"\u003e\u003ca href=\"https://stocktwits.com/symbol/ANVS\"\u003e\u003cimg style=\"aspect-ratio:1314/320;\" src=\"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/ANVS_sentiment_and_message_volume_Oct_16_2024_19c60dcfb9.png\" alt=\"ANVS sentiment and message volume Oct 16 2024.png\" width=\"1314\" height=\"320\"\u003e\u003c/a\u003e\u003cfigcaption\u003eANVS sentiment and message volume Oct 16 2024 as of 1:45 pm ET | source: Stocktwits\u003c/figcaption\u003e\u003c/figure\u003e\u003cp\u003eOn Stocktwits, retail sentiment for ANVS remained ‘bullish’ with ‘extremely high’ message volume following the company’s update.\u003c/p\u003e\u003cp\u003e\u003cstembedurl\u003ehttps://stocktwits.com/Cresskill198/message/589126954\u003c/stembedurl\u003e\u003c/p\u003e\u003cp\u003e\u003cstembedurl\u003ehttps://stocktwits.com/dwayne09/message/589126026\u003c/stembedurl\u003e\u003c/p\u003e\u003cp\u003eOn Tuesday, Annovis announced a successful End-of-Phase 2 meeting with the FDA, aligning both parties on a clear development path for buntanetap.\u003c/p\u003e\u003cp\u003eThe Phase 3 program will consist of two trials: a 6-month study focusing on symptomatic improvement and an 18-month study aimed at evaluating potential disease-modifying effects.\u003c/p\u003e\u003cp\u003eBuntanetap’s multi-target approach seeks to reduce toxic proteins like amyloid, tau, and alpha-synuclein, providing a comprehensive treatment option for neurodegenerative diseases such as Alzheimer’s and Parkinson’s.\u003c/p\u003e\u003cp\u003eStill, ANVS stock remains down over 50% this year.\u003c/p\u003e\u003cp\u003eRead next: \u003ca href=\"https://stocktwits.com/news-articles/markets/equity/csco-stock-jumps-after-citi-uprgade/cJczJmJRIR\"\u003e\u003cstrong\u003eCisco Stock Hits 13-Month High After Citi Upgrade: Retail Confidence Grows\u003c/strong\u003e\u003c/a\u003e\u003c/p\u003e","created_at":"2024-10-16T17:51:09Z","featured_image":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/vecteezy_miniature_doctors_checking_and_analyzing_a_brain_for_signs_2156239_b2c9290eb6.jpg","featured_image_attributes":{"alt_text":"On Tuesday, Annovis announced a successful End-of-Phase 2 meeting with the FDA, aligning both parties on a clear development path for buntanetap.","caption":"On Tuesday, Annovis announced a successful End-of-Phase 2 meeting with the FDA, aligning both parties on a clear development path for buntanetap. Representative image via Vecteezy","url":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/vecteezy_miniature_doctors_checking_and_analyzing_a_brain_for_signs_2156239_b2c9290eb6.jpg"},"headline":"Annovis Bio Stock Surges As Analyst Reiterates ‘Buy’ On Alzheimer’s Drug Progress: Retail Stays Bullish","image_url":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/vecteezy_miniature_doctors_checking_and_analyzing_a_brain_for_signs_2156239_b2c9290eb6.jpg","meta_description":"The FDA recently granted clearance for the company to proceed to Phase 3 trials, following successful Phase 2 results that showed improvement in Alzheimer’s patients.","meta_keywords":"annovis bio, annovis stock, anvs stock, FDA, Alzheimer's Disease","meta_title":"Annovis Bio Stock Surges As Analyst Reiterates ‘Buy’ On Alzheimer’s Drug Progress: Retail Stays Bullish","primary_symbol_code":"ANVS","sid":"cJczO3TRI2","source":{"id":1071,"source_name":"Stocktwits","url_domain":"stocktwits.com"},"subcategory":{"id":3,"name":"Equity","parent_id":2},"summary":"The FDA recently granted clearance for the company to proceed to Phase 3 trials, following successful Phase 2 results that showed improvement in Alzheimer’s patients.","symbol_codes":["ANVS","VTI","IWC","VXF"],"tags":[{"id":2,"tag_name":"Trending"},{"id":3,"tag_name":"Small Cap"},{"id":10,"tag_name":"Retail"}],"type":"article","updated_at":"2024-10-16T17:51:46Z","url_slug":"anvs-stock-jumps-after-analyst-reiterates-buy"},{"author":{},"canonical_url":"https://www.prnewswire.com/news-releases/beyond-the-horizon-innovative-drug-combinations-offer-new-hope-for-alzheimers-and-more-302266089.html","category":{"id":0},"content":"","created_at":"2024-10-03T12:30:00Z","headline":"Beyond the Horizon: Innovative Drug Combinations Offer New Hope for Alzheimer's and More","image_url":"","primary_symbol_code":"JNJ","sid":"cJcckYEblMMQ","source":{"id":93,"source_name":"PR Newswire","url_domain":"PR Newswire"},"subcategory":{"id":0},"summary":"Beyond the Horizon: Innovative Drug Combinations Offer New Hope for Alzheimer's and More Beyond the Horizon: Innovative Drug Combinations Offer New Hope for Alzheimer's and More PR Newswire NEW YORK...","symbol_codes":["JNJ","MRK","NVS","GSK","GSK.XLON","ANVS"],"tags":null,"type":"article","updated_at":"2024-10-03T13:15:01Z"},{"author":{"description":"Tyler Troup is from wealthyvc.com","designation":"Wealthy VC","id":7,"name":"Tyler Troup","profile_avatar":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/wealthy_V_Cavatar_1524535e0c.jpg","profile_link":"","social_media_links":{"facebook":"","twitter":"","website":"wealthyvc.com"},"type":"Stocktwits Contributor"},"canonical_url":"","category":{"id":2,"name":"Markets"},"content":"\u003cul\u003e\u003cli\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eAlzheimer’s Drug Market Faces Urgent Need for Innovative Therapies Beyond Big Pharma\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eSmall Biotech Companies Lead the Charge with Disruptive Approaches to Treating Alzheimer’s\u003c/span\u003e\u003c/li\u003e\u003c/ul\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eAlzheimer’s disease has been one of the most challenging conditions for the pharmaceutical industry to address. While companies like\u0026nbsp;\u003cstrong\u003eBiogen (BIIB)\u003c/strong\u003e and\u0026nbsp;\u003cstrong\u003eEli Lilly (LLY)\u003c/strong\u003e have made notable strides with drugs like\u0026nbsp;\u003cstrong\u003eAduhelm\u003c/strong\u003e and\u0026nbsp;\u003cstrong\u003eDonanemab\u003c/strong\u003e, which target amyloid plaques, breakthrough treatments that offer substantial cognitive improvements remain elusive. Despite these advancements, many of these drugs focus on slowing disease progression rather than providing a cure, and their impact has been limited.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eHistorically, much of the innovation in Alzheimer’s research has come from smaller biotech companies, many of which are eventually acquired by larger pharmaceutical firms like BIIB and LLY. However, the results from these acquisitions have often not met expectations, leaving room for new players to disrupt the market with more innovative approaches.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eFor investors looking for broader exposure to the biotech sector, the\u0026nbsp;\u003cstrong\u003eXBI ETF\u003c/strong\u003e (SPDR S\u0026amp;P Biotech ETF) offers a more diversified way to play the space. XBI tracks an equal-weighted index of U.S. biotech stocks, providing exposure to both large players like Biogen and smaller upstarts working on novel treatments. The ETF has seen strong performance recently, driven by optimism around biotech innovation in areas like Alzheimer’s, oncology, and rare diseases. While individual biotech stocks can be volatile, XBI spreads the risk across a broader portfolio, making it a compelling option for those looking to invest in the sector without taking on the higher risk of single-stock picks.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eThe Alzheimer’s drug market is projected to reach $13.7 billion by 2029, and despite the presence of big pharma, there remains a significant opportunity for companies with novel therapies to address this unmet need. In this article, we examine three small-cap biotech players —\u0026nbsp;\u003cstrong\u003eCassava Sciences (SAVA)\u003c/strong\u003e,\u0026nbsp;\u003cstrong\u003eINmune Bio (INMB)\u003c/strong\u003e, and\u0026nbsp;\u003cstrong\u003eAnnovis Bio (ANVS)\u003c/strong\u003e — that are working on breakthrough Alzheimer’s therapies. We will break down their potential by analyzing the good, the bad, the ugly, and their overall investability.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u0026nbsp;\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#2c2f34;font-family:Arial,sans-serif;\"\u003eRead Now:\u0026nbsp;\u003c/span\u003e\u003ca href=\"https://wealthyvc.com/featured/20m-healthcare-stock-breaks-out-after-rising-1700-on-medicare-and-medicaid-clearance-heres-whats-being-announced-in-the-coming-months-in-a-25x-larger-market/\"\u003e\u003cspan style=\"background-color:transparent;color:#3498db;font-family:Arial,sans-serif;\"\u003eThis $20m Company Soars 1,700% on Medicare \u0026amp; Medicaid Clearance— Find out What’s Being Announced in the Coming Months in a Market 25X Larger\u003c/span\u003e\u003c/a\u003e\u003c/h4\u003e\u003cp\u003e\u0026nbsp;\u003c/p\u003e\u003ch3\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003cstrong\u003eCassava Sciences (SAVA)\u0026nbsp;\u003c/strong\u003e\u003c/span\u003e\u003ca href=\"https://stocktwits.com/symbol/SAVA\"\u003e\u003cspan style=\"background-color:transparent;color:#1155cc;font-family:Arial,sans-serif;\"\u003e\u003cu\u003e[Follow on Stocktwits.com]\u003c/u\u003e\u003c/span\u003e\u003c/a\u003e\u003c/h3\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Lowdown:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eCassava Sciences is developing Simufilam, a drug that targets a unique protein misfolding pathway in Alzheimer’s disease. Unlike traditional therapies that focus solely on amyloid plaques, Simufilam aims to correct the shape of the protein Filamin A, which may influence multiple Alzheimer’s disease processes. This innovative approach could potentially address multiple aspects of the disease.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eCassava has faced a mix of positive and negative news. Its Phase 2 trial results showed cognitive improvement in Alzheimer’s patients, generating optimism. However, allegations of data manipulation have cast a cloud over the company’s achievements, leading to regulatory scrutiny and volatility in the stock.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Good:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eSimufilam’s unique approach could disrupt the Alzheimer’s drug market if Phase 3 trials confirm its efficacy. With Alzheimer’s treatments falling short of significant impact, a drug that improves cognitive function would undoubtedly capture massive attention. Additionally, Cassava’s high short interest could lead to a short squeeze if positive news emerges, providing an opportunity for investors to capitalize on sharp price movements. Notably, if the drug succeeds, the company’s stock could skyrocket, presenting massive upside potential for investors.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cimg src=\"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2024_10_03_at_11_27_24_AM_67dc564cb2.png\" alt=\"Screenshot 2024-10-03 at 11.27.24 AM.png\"\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Bad:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eThe allegations of data manipulation have raised questions about the integrity of Cassava’s research. Although the company has denied wrongdoing, the concerns could weigh heavily on investor confidence until the Phase 3 data is released. Moreover, Alzheimer’s disease is notoriously difficult to treat, and even promising drugs can fail in late-stage trials.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Ugly:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eCassava’s main challenge is that it’s a one-trick pony. The company’s future is almost entirely dependent on the success of Simufilam. If the Phase 3 trials show negative results, the stock could plummet, potentially wiping out investors. Cassava lacks diversification in its pipeline, and failure could be disastrous for the company’s long-term viability.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eInvestability:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eCassava Sciences is a high-risk, high-reward stock. For investors willing to take on significant risk, the potential upside of Simufilam is enormous. However, given the controversies surrounding the company, a cautious approach is warranted. Those looking for long-term gains should monitor the Phase 3 results closely before making any major investments.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u0026nbsp;\u003c/p\u003e\u003ch3\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003cstrong\u003eINmune Bio (INMB)\u0026nbsp; \u003c/strong\u003e\u003c/span\u003e\u003ca href=\"https://stocktwits.com/symbol/inmb\"\u003e\u003cspan style=\"background-color:transparent;color:#1155cc;font-family:Arial,sans-serif;\"\u003e\u003cu\u003e[Follow on Stocktwits.com]\u003c/u\u003e\u003c/span\u003e\u003c/a\u003e\u003c/h3\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Lowdown:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eINmune Bio is taking a unique approach to treating Alzheimer’s by focusing on neuroinflammation rather than the traditional amyloid or tau pathways. The company’s lead drug, XPro1595, is designed to reduce brain inflammation by neutralizing soluble TNF (sTNF), a cytokine that drives chronic inflammation in Alzheimer’s patients. This could potentially offer a complementary treatment to existing therapies. In addition to its Alzheimer’s focus, INmune Bio has a strong oncology portfolio, which includes its INKmune platform aimed at improving cancer immunotherapy.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eRecent clinical data on XPro1595 has been promising, with the drug showing efficacy in reducing neuroinflammation. The company is preparing for larger trials in 2025, which could solidify its position in the Alzheimer’s space.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Good:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eINmune Bio’s focus on neuroinflammation sets it apart from other Alzheimer’s treatments. Reducing inflammation has shown to be a crucial factor in preventing cognitive decline, and XPro1595’s early data suggests it could be a game-changer in this area. Furthermore, INmune Bio’s diversified portfolio, including its oncology platform, gives it additional avenues for growth beyond Alzheimer’s, reducing its risk compared to Cassava Sciences.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Bad:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eDespite the promise of XPro1595, the drug is still in early-stage trials, and it could take years before it reaches the market. The road to FDA approval is long and fraught with challenges, and investors will need to be patient as the company moves through its clinical development phases.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cimg src=\"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2024_10_03_at_11_28_27_AM_bf6e45fe54.png\" alt=\"Screenshot 2024-10-03 at 11.28.27 AM.png\"\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Ugly:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eOne of the biggest risks for INmune Bio is its reliance on early-stage data. While XPro1595 has shown promise, it has not yet demonstrated long-term efficacy in larger trials. Any setbacks in the trial process could delay the drug’s development and hurt the company’s stock.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eInvestability:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eINmune Bio offers the best reward-to-risk ratio among the three companies. With a diversified portfolio and a promising Alzheimer’s treatment, INmune Bio is well-positioned to capitalize on breakthroughs in both neuroinflammation and oncology. Investors looking for a biotech stock with high upside potential but less concentrated risk compared to Cassava Sciences may find INmune Bio to be a compelling option.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#2c2f34;font-family:Arial,sans-serif;\"\u003eRead Now:\u0026nbsp;\u003c/span\u003e\u003ca href=\"https://wealthyvc.com/featured/20m-healthcare-stock-breaks-out-after-rising-1700-on-medicare-and-medicaid-clearance-heres-whats-being-announced-in-the-coming-months-in-a-25x-larger-market/\"\u003e\u003cspan style=\"background-color:transparent;color:#3498db;font-family:Arial,sans-serif;\"\u003eThis $20m Company Soars 1,700% on Medicare \u0026amp; Medicaid Clearance— Find out What’s Being Announced in the Coming Months in a Market 25X Larger\u003c/span\u003e\u003c/a\u003e\u003c/h4\u003e\u003cp\u003e\u0026nbsp;\u003c/p\u003e\u003ch3\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003cstrong\u003eAnnovis Bio (ANVS)\u0026nbsp;\u003c/strong\u003e\u0026nbsp;\u003c/span\u003e\u003ca href=\"https://stocktwits.com/symbol/ANVS\"\u003e\u003cspan style=\"background-color:transparent;color:#1155cc;font-family:Arial,sans-serif;\"\u003e\u003cu\u003e[Follow on Stocktwits.com]\u003c/u\u003e\u003c/span\u003e\u003c/a\u003e\u003c/h3\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Lowdown:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eAnnovis Bio is targeting Alzheimer’s with Buntanetap, a drug that aims to reduce multiple neurotoxic proteins, including amyloid, tau, and alpha-synuclein. By taking a multi-pronged approach, Annovis hopes to provide a more comprehensive treatment for neurodegenerative diseases like Alzheimer’s and Parkinson’s.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eThe company recently reported positive early-stage trial results, showing that Buntanetap improved cognition in patients with Alzheimer’s. With a Phase 2 trial in progress, Annovis Bio is positioning itself as a serious contender in the Alzheimer’s space.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Good:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eBuntanetap’s ability to target multiple neurotoxic proteins gives it an advantage over single-target therapies. The early data showing cognitive improvement has bolstered investor confidence, and the drug’s potential to address both Alzheimer’s and Parkinson’s opens up additional market opportunities. If Buntanetap continues to perform well in clinical trials, Annovis Bio could see substantial growth.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cimg src=\"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/Screenshot_2024_10_03_at_11_29_39_AM_fafa150775.png\" alt=\"Screenshot 2024-10-03 at 11.29.39 AM.png\"\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Bad:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eHowever, Annovis Bio is still in the early stages of its clinical trials, and the road to commercialization is long. The company will need to demonstrate consistent efficacy in larger trials before it can become a serious player in the Alzheimer’s market. Additionally, competition from other multi-target therapies could limit its market share.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eThe Ugly:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eLike many small biotech companies, Annovis Bio is reliant on the success of a single drug candidate. If Buntanetap fails in its clinical trials, the company could struggle to recover. Investors should be aware of the high risk associated with this stock.\u003c/span\u003e\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003ci\u003eInvestability:\u003c/i\u003e\u003c/span\u003e\u003c/h4\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eAnnovis Bio presents a speculative but potentially rewarding investment. The company’s multi-target approach could offer greater efficacy than traditional Alzheimer’s treatments, but it remains a high-risk bet. Investors should monitor the progress of its clinical trials closely before making any significant investments.\u003c/span\u003e\u003c/p\u003e\u003ch3\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u003cstrong\u003eConclusion\u003c/strong\u003e\u003c/span\u003e\u003c/h3\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eThe Alzheimer’s drug market is poised for disruption, and companies like Cassava Sciences, INmune Bio, and Annovis Bio are leading the charge with innovative treatments. While these stocks come with substantial risks, the potential rewards could be life-changing — both for patients and investors. For those willing to take a gamble on the future of Alzheimer’s treatment, these companies offer a unique opportunity to not only achieve significant financial gains but also to contribute to a cause that could improve millions of lives.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eOf the three, INmune Bio stands out for its diversified portfolio and promising early data, making it a potentially safer bet. Cassava Sciences offers the most dramatic upside but comes with higher risks due to its single-drug focus. Annovis Bio, while speculative, offers intriguing potential with its multi-targeted approach.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eAs always, investors should weigh the risks and rewards carefully but know that their investments could make a profound difference in the fight against one of the most challenging diseases of our time.\u003c/span\u003e\u003c/p\u003e\u003cp\u003e\u0026nbsp;\u003c/p\u003e\u003ch4\u003e\u003cspan style=\"background-color:transparent;color:#2c2f34;font-family:Arial,sans-serif;\"\u003eRead Now:\u0026nbsp;\u003c/span\u003e\u003ca href=\"https://wealthyvc.com/featured/20m-healthcare-stock-breaks-out-after-rising-1700-on-medicare-and-medicaid-clearance-heres-whats-being-announced-in-the-coming-months-in-a-25x-larger-market/\"\u003e\u003cspan style=\"background-color:transparent;color:#3498db;font-family:Arial,sans-serif;\"\u003eThis $20m Company Soars 1,700% on Medicare \u0026amp; Medicaid Clearance— Find out What’s Being Announced in the Coming Months in a Market 25X Larger\u003c/span\u003e\u003c/a\u003e\u003c/h4\u003e\u003cp\u003e\u0026nbsp;\u003c/p\u003e\u003cp\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003eThis author or the principals of WVC do not hold any of the stocks mentioned in this article.\u0026nbsp;\u003c/span\u003e\u003c/p\u003e\u003cul\u003e\u003cli\u003e\u003ca href=\"http://www.stocktwits.com/wealthyvc\"\u003e\u003cspan style=\"background-color:transparent;color:#1155cc;font-family:Arial,sans-serif;\"\u003e\u003cu\u003eFollow us on Stocktwits\u003c/u\u003e\u003c/span\u003e\u003c/a\u003e\u003cspan style=\"background-color:transparent;color:#000000;font-family:Arial,sans-serif;\"\u003e\u0026nbsp;\u003c/span\u003e\u003c/li\u003e\u003cli\u003e\u003ca href=\"https://www.facebook.com/groups/WealthyVC\"\u003e\u003cspan style=\"background-color:transparent;color:#3498db;font-family:Arial,sans-serif;\"\u003eJoin the Discussion in the WVC Facebook Investor Group\u003c/span\u003e\u003c/a\u003e\u003c/li\u003e\u003cli\u003e\u003cspan style=\"background-color:transparent;color:#2c2f34;font-family:Arial,sans-serif;\"\u003eHave a Stock Tip or New\u0026nbsp; Story Suggestion? Email us at\u0026nbsp;\u003c/span\u003e\u003cspan style=\"background-color:transparent;color:#3498db;font-family:Arial,sans-serif;\"\u003eInvest@WealthyVC.com\u003c/span\u003e\u003c/li\u003e\u003c/ul\u003e","created_at":"2024-10-03T06:04:42Z","featured_image":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/wealthyvc_12445ce5f9.png","featured_image_attributes":{"alt_text":"","caption":"","url":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/wealthyvc_12445ce5f9.png"},"headline":"Big Pharma’s $13.7B Alzheimer’s Drug Market Has a Progress Problem: Here Are Three Small-Cap Biotech Stocks That Could Disrupt the Market","image_url":"https://st-everywhere-cms-prod.s3.us-east-1.amazonaws.com/wealthyvc_12445ce5f9.png","meta_description":"Discover how small-cap biotech companies like Cassava Sciences, INmune Bio, and Annovis Bio are shaking up the $13.7 billion Alzheimer’s drug market with innovative treatments. Explore their potential for high-risk, high-reward gains","meta_keywords":"Alzheimer’s drug market, biotech innovation, Cassava Sciences, INmune Bio, Annovis Bio, Alzheimer’s treatments, Simufilam, Buntanetap, XPro1595, biotech stocks, Alzheimer’s research.","meta_title":"Big Pharma’s $13.7B Alzheimer’s Drug Market Has a Progress Problem: Here Are Three Small-Cap Biotech Stocks That Could Disrupt the Market","primary_symbol_code":"BIIB","sid":"cJcc9LER3p","source":{"id":1075,"source_name":"Stocktwits Contributor","url_domain":"stocktwits.com"},"subcategory":{"id":3,"name":"Equity","parent_id":2},"summary":"Small biotech firms like Cassava Sciences, INmune Bio, and Annovis Bio are developing innovative Alzheimer’s treatments, disrupting big pharma’s dominance in the $13.7B market. For those targeting groundbreaking therapies, high-risk, high-reward investments lie ahead.\n","symbol_codes":["BIIB","LLY","XBI","SAVA","INMB","ANVS"],"tags":[{"id":10,"tag_name":"Retail"},{"id":12,"tag_name":"Sponsored"}],"type":"article","updated_at":"2024-11-13T06:06:48Z","url_slug":"big-pharma-s-13-7-b-alzheimer-s-drug-market-has-a-progress-problem-here-are-three-small-cap-biotech-stocks-that-could-disrupt-the-market"},{"author":{},"canonical_url":"https://www.prnewswire.com/news-releases/transforming-alzheimers-treatment-innovative-combinations-to-boost-cognition-302263275.html","category":{"id":0},"content":"","created_at":"2024-10-01T12:30:00Z","headline":"Transforming Alzheimer's Treatment: Innovative Combinations to Boost Cognition","image_url":"","primary_symbol_code":"ABBV","sid":"cJTy3hPblpFD","source":{"id":93,"source_name":"PR Newswire","url_domain":"PR Newswire"},"subcategory":{"id":0},"summary":"Transforming Alzheimer's Treatment: Innovative Combinations to Boost Cognition Transforming Alzheimer's Treatment: Innovative Combinations to Boost Cognition PR Newswire NEW YORK, Oct. 1, 2024...","symbol_codes":["ABBV","NVO","PFE","ABBV","ANVS","LLY"],"tags":null,"type":"article","updated_at":"2024-10-01T13:15:02Z"},{"author":{},"canonical_url":"https://www.tipranks.com/news/company-announcements/annovis-bio-raises-7-million-from-warrant-exercises?utm_source=alphanewsstream.com\u0026utm_medium=referral","category":{"id":0},"content":"","created_at":"2024-07-11T13:00:20Z","headline":"Annovis Bio Raises $7 Million from Warrant Exercises","image_url":"","primary_symbol_code":"ANVS","sid":"c7AOXCCbjCG8","source":{"id":990,"source_name":"TipRanks Financial Blog","url_domain":"www.tipranks.com"},"subcategory":{"id":0},"summary":"An update from Annovis Bio (ANVS) is now available. Annovis Bio, Inc. has successfully exercised 0.8 million warrants issued in November 2023, resu...","symbol_codes":["ANVS"],"tags":null,"type":"article","updated_at":"2024-07-11T13:00:20Z"},{"author":{},"canonical_url":"https://www.tipranks.com/news/blurbs/maxim-group-sticks-to-its-hold-rating-for-annovis-bio-anvs?utm_source=alphanewsstream.com\u0026utm_medium=referral","category":{"id":0},"content":"","created_at":"2024-07-10T13:00:21Z","headline":"Maxim Group Sticks to Its Hold Rating for Annovis Bio (ANVS)","image_url":"","primary_symbol_code":"ANVS","sid":"c7AJEuzbjyCO","source":{"id":990,"source_name":"TipRanks Financial Blog","url_domain":"www.tipranks.com"},"subcategory":{"id":0},"summary":"Maxim Group analyst Jason McCarthy maintained a Hold rating on Annovis Bio (ANVS Research Report) yesterday. The company's shares opened today at...","symbol_codes":["ANVS"],"tags":null,"type":"article","updated_at":"2024-07-10T13:00:21Z"},{"author":{},"canonical_url":"https://www.benzinga.com/insights/short-sellers/24/07/39623921/peering-into-annovis-bios-recent-short-interest?utm_source=TechInvestorNews\u0026utm_campaign=partner_feed\u0026utm_medium=partner_feed\u0026utm_content=site","category":{"id":0},"content":"","created_at":"2024-07-04T13:00:13Z","headline":"Peering Into Annovis Bio's Recent Short Interest","image_url":"","primary_symbol_code":"ANVS","sid":"c7qu6znbjD22","source":{"id":104,"source_name":"Benzinga","url_domain":"Benzinga"},"subcategory":{"id":0},"summary":"read 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more...","symbol_codes":["ANVS"],"tags":null,"type":"article","updated_at":"2024-07-04T13:00:13Z"},{"author":{},"canonical_url":"https://www.benzinga.com/markets/equities/24/07/39611561/tesla-paramount-global-annovis-bio-eli-lilly-amazon-why-these-5-stocks-are-on-investors-radars-t?utm_source=TechInvestorNews\u0026utm_campaign=partner_feed\u0026utm_medium=partner_feed\u0026utm_content=site","category":{"id":0},"content":"","created_at":"2024-07-04T13:00:12Z","headline":"Tesla, Paramount Global, Annovis Bio, Eli Lilly, Amazon: Why These 5 Stocks Are On Investors' Radars Today","image_url":"","primary_symbol_code":"ANVS","sid":"c7qu6zVbjwCC","source":{"id":104,"source_name":"Benzinga","url_domain":"Benzinga"},"subcategory":{"id":0},"summary":"On Tuesday, the Dow Jones Industrial Average rose by 0.4%, closing at $39,331.85, while the S\u0026P 500 also ended the day in positive territory.\nread 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