CINXE.COM

<!DOCTYPE html><html lang="en-US"><head><title>Just a moment...</title><meta http-equiv="Content-Type" content="text/html; charset=UTF-8"><meta http-equiv="X-UA-Compatible" content="IE=Edge"><meta name="robots" content="noindex,nofollow"><meta name="viewport" content="width=device-width,initial-scale=1"><style>*{box-sizing:border-box;margin:0;padding:0}html{line-height:1.15;-webkit-text-size-adjust:100%;color:#313131;font-family:system-ui,-apple-system,BlinkMacSystemFont,Segoe UI,Roboto,Helvetica Neue,Arial,Noto Sans,sans-serif,Apple Color Emoji,Segoe UI Emoji,Segoe UI Symbol,Noto Color Emoji}body{display:flex;flex-direction:column;height:100vh;min-height:100vh}.main-content{margin:8rem auto;max-width:60rem;padding-left:1.5rem}@media (width <= 720px){.main-content{margin-top:4rem}}.h2{font-size:1.5rem;font-weight:500;line-height:2.25rem}@media (width <= 720px){.h2{font-size:1.25rem;line-height:1.5rem}}#challenge-error-text{background-image:url(data:image/svg+xml;base64,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);background-repeat:no-repeat;background-size:contain;padding-left:34px}@media (prefers-color-scheme:dark){body{background-color:#222;color:#d9d9d9}}</style><meta http-equiv="refresh" content="120"></head><body class="no-js"><div class="main-wrapper" role="main"><div class="main-content"><noscript><div class="h2"><span id="challenge-error-text">Enable JavaScript and cookies to continue</span></div></noscript></div></div><script>(function(){window._cf_chl_opt={cvId: '3',cZone: "publications.waset.org",cType: 'non-interactive',cRay: '91357d57db353f4b',cH: 'BcgaYmtSnNNLBtNglQj7zXTwmqUelgCkbiqC97jkdwg-1739792290-1.2.1.1-JYaqRbENWJqUnWtH8ww0w48X11ClDMb2YwZsnA0uNs2bIiq1R_ALkK_p.u2g19IP',cUPMDTk: "\/abstracts\/search?q=obese%20mice&__cf_chl_tk=mk8KOsKW23.WZfeMxeARaApWd5iV_7SqvGvPzTsXJXk-1739792290-1.0.1.1-P9jx2IzrNbk0ZED4zw2wi.sCR0ABfo46YXPuFKYvBuE",cFPWv: 'b',cITimeS: '1739792290',cTTimeMs: '1000',cMTimeMs: '120000',cTplC: 0,cTplV: 5,cTplB: 'cf',cK: "",fa: "\/abstracts\/search?q=obese%20mice&__cf_chl_f_tk=mk8KOsKW23.WZfeMxeARaApWd5iV_7SqvGvPzTsXJXk-1739792290-1.0.1.1-P9jx2IzrNbk0ZED4zw2wi.sCR0ABfo46YXPuFKYvBuE",md: "EXBRL5OIMqwngilS7DBMB.Jf9CPQLc3M2x1ge5szyRc-1739792290-1.2.1.1-Hf2NNMFNM4.btg3.t_G1lIzXoZPLxft4Al0y_aNTltfkIpJJ0HiLYggDowhKCovoqF.YUDaF4dOCEVbN4VOsLEXMtIDYj_q_2gt7KRALlMWkMVdu2iGLVebNQfxDUkLBLsbrar4FAlMceC4em7vrjzhDExIUiDsu46HsZOAcyyKLt8CgJxFe_fXNIa6MPKrYtmc4KPb3R0ylifoCEPdUDH_wzCxfclsQk81tySadvFggv8Vv4FeyX1IRfvzcSjekp2fj4ctId4yAMDy7XTbLdVOA9U8ni.lE2xRFCXp2W5J08lEzOQ6ftKuMIxl7NFgmMMnyt3v36r0pcFy_l60PMcii80eIqf3ZvWeFfuPZeLQhJThw0L5lzc8lINFyc1abmRHnftHMkM.k3z8IlIMdLAafdgJ8u0iWFFukRXzsjaNKcQD2xun8qPEBvZpTuFhzFQmod7tcKnSfGzhjyXHqWvfzD1on2jgpnASUtZl1rKkU2Zn88vjXzlgn4g1xmz0kcRH28EyG7R2tp5Drw8dN7wWvikU3zqyRLUmVjZuqWMEGqJ8DBf.l4ztF7y0JQrNAqMPqwybWJO.A3OwSAt1jco7zbdmTnCVQjPtwqA93N8xjYKpC6WKPBE9yZXMghfWqx8F5oJIDZF4NteypRPUOeS2whHgPbXPPJYPYIvJXTf.MrX3pU0TwxeqZPszKflZa5_NL0kJG2ym4EqM0rPaOcqTQIXaTvhZCnW9WZE5kgyMKr2La9drQmqYgZ1p1EpbW1oQXwJaRtegES4Oq_GE0jARZPd0U6a2e83DAn2yOPJ9DUvpOE33mxt3FaVfrD1ef65p72MVhG3cJDusDSbQWmbcO6Z841uYdWsIYlO4RaD5dG9v3Nbhd_dtmFjufZ.Uu_lJq7Gvf6SEx8wRuc03Wcn1aQ1h8sNql.Aed3pRd461.DZyoZjBoT1r7W2Bd4KSXJnvWHGe3BnGVxgUFZnqGPzY9W.R7gp0gG46v_0xSa81uMydbpQw2sakmHWvCfMcV3K51Np8TaScZBC2MA5k.WyK.meTAs5XYGk4tLGOKHeqJ3isll9OG8plxEGOIwCP_P9vTpHNcgh52ZxpC3sMRxUmHUmiixb4UW.kzL16UPrCVF1x8GGNGmc_LBIogIeaWMDb4Pg_CjbKGfjIoEhTDRUeUvaWwKE0w9HcEoJPRD_Mu5czoGhXuQ6PDPdJRsVh56o7V_ucWaoFKWjUCNljz.mgvTXtZIwHYGEWBzECP2kDVD0B_X6ac5y220nOKvFQdgqFU9JA8_gefygnQlmbR6jxU0xKLUjy8f4hwV3X6ou6.V1ZmkXyV0C2ma23wmKXvNFCZOV3yfIdZ_sNOw.O.LE09M3L2MxdP1oMpvNuYfFLQPp9KyGXCQX8IULr4tKgn1OxZucZKY_bM__i30Gb5APohskdUhRFH2UJx6GmQUaIXKwp1K7b2_b.FYfVqYDoqy7pMl3l5pFElOKqSuCrEs4pKT3iCGnXbHe2w5fQSmfn6OJ.C_.5LabQNCiyyuZa8AiuZo5h_7r3rmVEppdGd5B9i_xVgmincz_PNT3BJ0DKrsOVIiUKT2TqZxHlOGLZSTKKBmcmgPAffprfVEmZ84zq448MP05EPV4o3z2694kfvh8guyAu1xFBY9YQgdhMf9vM6CunreHrTAL4R3Dr8Tkgz5piX.OOEEiZCtKGThVWD_dvMAoCwN1l_B8f6bXMbpoKgpa_scla.NxmrK1YcSUGxUoev02q299uIS13A8KOjO69o9p2Qzc_XltppfziXclSK8zHGMxo9wl9b0Ol5Ex57zfZBTwBi9LGqxhRaOX657KWTV2A.iav8dNpZ8NL16ZnLW1hqAjw1dsU0ae4vbmSc8U7iMHqiOQRAjlnF3JvgC6._PXFHX.eUoBQ7DKAGkuy9GTlGCjFg.sGgPuZ6Vg",mdrd: "FgIgGa1sV76oHvSSYCRyfxnM6sCDAgDNI.JFbMCye5k-1739792290-1.2.1.1-VxRhwMMBDrPoWRxzIYcIoi1Re_Jk.IAN.1BHmqozsnQAC7lCSzF8Hluk78ytKzL49OAiOEGocIBl3FcJLLIRsjV.n3s3qtoy2SxYcVrWENrHxUiIGtyW2dwaYVPGsPoWipP8wkZRCl01tA1fbo.8_kA1sUSDG4wqzMRnEOx85oO_cdVP0dVp7A1DkzogclX6d8pSbQ_oXvZutIWePgGGGH1RedysJuONp6FvPFCoUi2s9hQr602d4vOV_mOTuoIrtXdhzG6dylL4t1VIT21frAWStrEm9fPtz_VR.n6E5ElTxYKhbpn8kkbziqgqpyz6wz1RfUSsK89izGCskRniuH6a0XEtTTor0GRcAFZQE5DpeT2ZPaygXPZTSY6tV4uEbnegVMg.EqhT1pnV_uNfGSu9Mt5dHf3OS2Sq2Em20YFeZbzBvL75Jdma_mkz3ECGvlYPAAyIGpFrkoYZJ0K1MWr4kIwysnDibuswvgHOpWAqO6xBYgK8g9EobSj93iQnqdMTs3XNn8U8Pyxmu9zSf7IyqQDXytj5T9vJLtbFlz4ROaIxC4gl6oxeeiAbN6iAIBMHnXnqL_DhifExl4MsxvcPWnHUs7mOaGKk9q4PNu11xF.CEpgT82RwzvsnELUPBi2h2WBLpOcyDwClpsnXO_MLXgn1UXyDFi26NuYuuSXUUUsmw7VryKNLtRzyYVPXB0dPXYk6vBz6h1_7UEBEseKB5Tui6Ul3PDB1zd9dCja2TXx9OJFv5MR3Jmoy5jz7rt6FDan8bsOY05nIh6gflM0mRHhS4Y9MXo_jib54RHYyn2tlnL2Yrj8X3JCEb_AVEQB4FVMCCPU2_9ZkWiPrQlykspYDfQi3tYokCklZdgvgTnNTsAe1KCfv8RfUH.6Xb029I5DjDp4IIPl80VYsRFm5J85CyI4IHFvCCaVjaTM2SbPum1XMwL3kckHeRXOl6giR7r9Dbsjw5PFgvmy1ilDFW84Ao1jmrwQCbVLYocZfMk79XWQtNBs6MUxuit5Ksg_fUyfzdunIKvmsHnzKQ.lF7DCZqS5faJxCee6fBaR_vpcqwygkZoM34aHExpFJajNfRRjNgFxvJ47ydkybto8dW2PinBhy1GKUKxAoZGJiLpMAORb8Ak5lQMrE3eErZ8UYcvaq63HHwJ0iV3iWqf.zcorsQWpLy0mqyru7vbQZoalTX87DcwANDNZCENugpneaEkgcYxSNIjXJ72yEXW4eds9Xk0IXQeAtgv8mAXmhnEKiCUtgT_tHXu2lsVzz4cTLDKLNDU4GT1IKS1uH2pJFi05QgZDStGMrIocCVZnuoYBW2OCDVfdxOofVAQUJNQVJl406sGX7G0ujS0fWESH._N4hnZLMBrniDlyVhTTQdF7gEZ8khFLWq0frK8ryjlRlEiQEgo.UY9gs6fW5hEdSs96DCysU9geZ7HZAq7CmCASRbvu.Ceze.XSqxM3dhhbzVkUhcDQPoyjyCLDiphaLLbf8fU_8TqaslPVTXr41Y1mVwRjob5Vk6UMVPlNdxIeiLuY5DKOPyZ8D6iO6TQWQ5ICXYzPA.h.5B6WERawZjgxtxQbJ8HXfPJcboYnjek.f0aD8_2BoMCTIUxLd100zlk2Mb9MnRpoJ2RWYrR_KgVGG.YNjgAuuw8B4LcyZDWs.kQjpc2stvBGcSh3QzWzwORmnGHGUJk5b2Vi17yxUncFIERzybNksHDaJ6q2etrvHnp2NMPNSbLZO8Pd9SiNtTxVDUas1RCqBCZTuY1Xb0XO7jGaZ3AHpEF0SqiBh6PA87iJ1xP.PzeaaSpF9F0UZVjPWG.0nGtJoRnova50a.qLudPjXTCXYXtGWPA37dRlADo53RBlZt5v_uu4moLaSrJqQ7aIvitnEwsgGH.KFH0_Gax8khR8wkk1zHg41iW4.1s64OdoTIwTnjq0pnhrXLKzjhTq9r3aNFexhYAchMxEpmIiodvtXGG3VVyuc"};var cpo = document.createElement('script');cpo.src = '/cdn-cgi/challenge-platform/h/b/orchestrate/chl_page/v1?ray=91357d57db353f4b';window._cf_chl_opt.cOgUHash = location.hash === '' && location.href.indexOf('#') !== -1 ? '#' : location.hash;window._cf_chl_opt.cOgUQuery = location.search === '' && location.href.slice(0, location.href.length - window._cf_chl_opt.cOgUHash.length).indexOf('?') !== -1 ? '?' : location.search;if (window.history && window.history.replaceState) {var ogU = location.pathname + window._cf_chl_opt.cOgUQuery + window._cf_chl_opt.cOgUHash;history.replaceState(null, null, "\/abstracts\/search?q=obese%20mice&__cf_chl_rt_tk=mk8KOsKW23.WZfeMxeARaApWd5iV_7SqvGvPzTsXJXk-1739792290-1.0.1.1-P9jx2IzrNbk0ZED4zw2wi.sCR0ABfo46YXPuFKYvBuE" + window._cf_chl_opt.cOgUHash);cpo.onload = function() {history.replaceState(null, null, ogU);}}document.getElementsByTagName('head')[0].appendChild(cpo);}());</script></body></html>