CD3 Protein - A hot target for bispecific antibody

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href="/P4836-ActiveMax%C2%AE-Human-T-cell-ActivationExpansion-CD3CD28-Beads-Premium-grade(Pre-GMP) (Pre-GMP)-DMF-Filed.html" >Activation CD3/CD28 Beads</a></li> <li><a href="/A2107-Solutions-for-T-Cell-Activation-and-Culture.html" >Solutions for T Cell Activation and Culture</a></li> <li><a href="/A2107-Solutions-for-T-Cell-Activation-and-Culture.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Cell Media Additives</h2> <ul> <li><a href="/A2560-ECMproteins.html" >Extracellular Matrix (ECM) Proteins</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix Basement Membrane Extracts</a></li> <li><a href="/A2612-Laminin.html" >Laminin Proteins</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cell Culture Medium</h2> <ul> <li><a href="/A2660-T-cell-culture-media.html" >CelThera™ GMP T Cell Expansion Medium</a></li> </ul> </div> <div class="pane_box_link"> <h2>Others</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> <li><a href="/A1888-Custom-GMP-Services.html" >Custom GMP Protein Services</a></li> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >More >></a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Kits & Assay Reagents <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box4 pane_boxB"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/Product_hand05.jpg" alt="Kits & Assay Reagents"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>ELISA</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Detection Kits</a></li> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Biomarker Detection Kits</a></li> <li><a href="/A1096-Inhibitor-Screening-Kits.html" >Inhibitor Screening Kits</a></li> <li><a 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<li><a href="/P6840-resDetect%E2%84%A2-E1A--SV40LTA-resDNA-Quantitation-Kit-%28qPCR%29.html" >E1A & SV40LTA Residual DNA Kit</a></li> <li><a href="/P6842-resDetect%E2%84%A2-Plasmid-resDNA-Quantitation-Kit-%28qPCR%29.html" >pDNA Residual DNA Kit</a></li> <li><a href="/search-keywords-Mycoplasma.html" >Mycoplasma Rapid Detection Kit</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Flow Cytometry</h2> <ul> <li><a href="/P7817-ClinMax%E2%84%A2-Human-TBNK-6-color-Cocktail-Flow-Panel.html" >Human TBNK 6-color Cocktail Flow Panel</a></li> <li><a href="/search-keywords-Th1/Th2%20cytokine.html" >Human Th1/Th2 Cytokine Kit (Flow Cytometry Multiplex Bead Assay)</a></li> <li><a href="/A1128-Pre-Coupling-Magnetic-Beads.html" >Pre-coupled Magnetic Beads</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplexed Flow Cytometry</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >Streptavidin (SA) Series Products</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>ADC Conjugation Kits</h2> <ul> <li><a href="/search-keywords-mmae-nature-9-w-na9.html" >AgLink ADC Kit - MMAE</a></li> <li><a href="/A1210-Targets-for-Antibody-Drug-Conjugates.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>MPCLIA</h2> <ul> <li><a href="/A2038-MPCLIA.html" >MPCLIA Reagents</a></li> </ul> </div> <div class="pane_box_link"> <h2>Other Kits</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> <li><a href="/A1126-Antigens--Antibodies-for-Diagnostic-Kit-Development.html" >Antibody Pairs</a></li> <li><a href="/A2146-Nuclease-Detection-Kits.html" >RNase / DNase Detection Kits</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" >Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="/search-keywords-elispot.html" >ELISpot Assay Kits</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title">Viral Antigens&Antibodies&Kits <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box5 pane_boxB"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/Product_hand02.jpg" alt="Viral Antigens"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>SARS-CoV-2</h2> <ul> <li><a href="/A1226-SARS-CoV-2_spike_mutants.html" >Variants of SARS-CoV-2 SARS-CoV-2 Related Products</a></li> <li><a href="/A1111-SARS-CoV-2-Related-Products.html" >SARS-CoV-2 Related Products</a></li> <li><a href="/A1167-Solutions-for-COVID-19-vaccine-safety-and-immunogenicity-evaluation.html" >Workflow for Vaccine R&D</a></li> </ul> </div> <div class="pane_box_link"> <h2>Varicella Zoster Virus</h2> <ul> <li><a href="/search-keywords-Glycoprotein E (VZV).html" >Glycoprotein E (VZV Antigen)</a></li> <li><a href="/search-keywords-VZV-nature-1-w-na1.html" >Anti-Glycoprotein E Antibody</a></li> <li><a href="/A2374-VZV-vaccine.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Influenza Virus</h2> <ul> <li><a href="/L-141-Hemagglutinin%20(HA).html" >Natural HA Trimer</a></li> <li><a href="/L-332-Neuraminidase%20(NA).html" >Natural NA Tetramer</a></li> <li><a href="/A2523-Flu.html" >HA & NA Antibody</a></li> <li><a href="/A2502-Influenza-Vaccine-Research-Customized-Services.html" >Customized Service</a></li> <li><a href="/A2523-Flu.html" >More >></a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Respiratory Syncytial Virus</h2> <ul> <li><a href="/search-nature-6-molecule-1484-keywords-RSV-w-na6_mo1484.html" >Pre-fusion Glycoprotein</a></li> <li><a href="/search-nature-6-keywords-RSV-molecule-1530-w-na6_mo1530.html" >Post-fusion Glycoprotein</a></li> <li><a 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Organoids</a></li> <li><a href="/A2582-Liver-Organoid-Solutions.html" >Liver Cells</a></li> <li><a href="/A2582-Liver-Organoid-Solutions.html" >Liver Services</a></li> <li><a href="/A2582-Liver-Organoid-Solutions.html" >Liver Case Studies</a></li> <li><a href="/A2398-Disease-and-human-models.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Organoid Culture Reagents</h2> <ul> <li><a href="/A1904-Organoid-Culture.html" >Cytokines for Organoid Culture</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix for Organoid Culture</a></li> <li><a href="/A2398-Disease-and-human-models.html#MoreRT" >More >></a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Others <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box6 pane_boxB"> <div class="pane_box_img"><img width="100%" 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Equipments</h2> <ul> <li><a href="/P7052-Automatic-Nucleic-Acid-Extraction-System.html" >Automatic Nucleic Acid Extraction System</a></li> <li><a href="/P7052-Automatic-Nucleic-Acid-Extraction-System.html" >More >></a></li> </ul> </div> </div> </div> </li> <div class="layui-menu-body-titleA"> Search by Modality </div> <li class="layui-menu-item-parent" > <div class="layui-menu-body-title upA"> <a href="/A2471-Cell-_Therapy-_Solutions.html">Cell Therapy </a><i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_1" > <div class="layui-menu-body-title layui-menu-body-title2"> Cell Therapy </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow" > <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_a.jpg" alt="Discovery & Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>CAR Targets</h2> <ul> <li><a href="/A1088-CD19%EF%BC%9Aa-validated-therapeutic-target-for-B-cell-malignancies.html" >CD19 Protein</a></li> <li><a href="/search-keywords-BCMA-molecule-36-w-mo36.html" >BCMA Protein</a></li> <li><a href="/search-keywords-MSLN.html" >MSLN Protein</a></li> <li><a href="/A1971-Hematological-Malignancies.html" >Hematologica Malignancies CAR Targets</a></li> <li><a href="/A1861-Solid-Tumor-CAR-Targets.html" >Solid Tumor CAR Targets</a></li> <li><a href="/A1041-Targets-of-CAR-T-Cell-Therapy.html" >More Targets >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Universal CAR Detection Tool</h2> <ul> <li><a href="/search-keywords-G4S%20Linker.html" >Anti-G4S linker Antibody</a></li> <li><a href="/L-422-Protein%20L.html" >Protein L</a></li> </ul> </div> <div class="pane_box_link"> <h2>Other Target Proteins</h2> <ul> <li><a href="/A1656-MHC-Class-I-Complex-Custom-Service.html" >MHC-peptide Complexes</a></li> <li><a href="/A1536-Proteins-for-Neuroscience.html" >Aneuro - Proteins for Neuroscience</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>General Proteins</h2> <ul> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA Series Products</a></li> </ul> </div> <div class="pane_box_link"> <h2>Drug Screening Service</h2> <ul> <li><a href="/A1151-SPR-BLI-analytical-service.html" >SPR /BLI analytical service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics Development</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cell Culture Products</h2> <ul> <li><a href="/A1798-cell-culture-cytokines.html" >Cell Culture Growth Factors & Antibodies</a></li> <li><a href="/A2660-T-cell-culture-media.html" >CelThera™ GMP T Cell Expansion Medium</a></li> <li><a href="/A1595-ActiveMax®-Cytokines.html" >ActiveMax Cell Activation Beads</a></li> <li><a href="/A2560-ECMproteins.html" >Extracellular Matrix (ECM) Proteins</a></li> <li><a href="/A2097-iPSC-Culturing.html" >CMC Production Process of iPSC-based Cell Therapy</a></li> <li><a href="/A2612-Laminin.html" >Laminin Proteins for Clinical iPSC Banking</a></li> <li><a href="/A1904-Organoid-Culture.html" >Cytokines for Organoid Culture</a></li> <li><a href="/A1813-Neural-Factors.html" >Aneuro - Neural Factors</a></li> <li><a href="/A2495-TcellCMC.html" >CMC Production Process of Adoptive T Cell Therapies</a></li> </ul> </div> <div class="pane_box_link"> <h2>Premium(Pre-GMP) grade Raw Materials</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >Premium(Pre-GMP) Growth Factors</a></li> <li><a href="/P5481-GMP-Monoclonal-Anti-Human-CD3-Antibody-%28OKT3%29-DMF-Filed.html" >GMP Grade Antibodies</a></li> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP Grade GENIUS™Nuclease </a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> <li><a href="/A1595-ActiveMax®-Cytokines.html" >ActiveMax Cell Activation Beads</a></li> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >Key Raw Materials for CGT</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal Products</h2> <ul> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP Grade GENIUS™Nuclease </a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> <div class="pane_box_link"> <h2>Gene Editing Products</h2> <ul> <li><a href="/A1657-CRISPR-Cas-technology.html" >GENPower - Cas Enzymes</a></li> <li><a href="/A1301-enzyme-products.html#mRNA_enzymeA" >mRNA Synthesis Enzymes</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Large-Scale Manufacturing</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >GMP-grade Raw Materials</a></li> <li><a href="/A1888-Custom-GMP-Services.html" >GMP Protein Services</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_c.jpg" alt="CMC-Quality Control"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" target="_blank" >Residual Host Cell DNA / RNA Detection Kits</a></li> <li><a href="/search-keywords-Activity.html" target="_blank" >RNase / DNase Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" target="_blank" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/P7814-resDetect%E2%84%A2-BSA-ELISA-Kit.html" target="_blank" >Residual BSA ELISA Kit</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html#pro" target="_blank" >Residual Cell Culture Materials Detection Kits</a></li> <li><a href="/P6991-resDetect%E2%84%A2-Kanamycin-ELISA-Kit.html" target="_blank" >Residual Antibiotics Detection Kits</a></li> <li><a href="/P7281-resDetect%E2%84%A2-HIV-1-p24-ELISA-Kit-%28Residue-Testing%29.html" target="_blank" >Residual HIV-1 p24 ELISA Kit</a></li> <li><a href="/search-keywords-Mycoplasma.html" target="_blank">Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" target="_blank">Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="/A2504-resDetect-CGT.html" target="_blank" >CGT CMC Manufacturing Process Residue Detection Solutions</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>CAR Detection Tools</h2> <ul> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/L-1788-G4S%C2%A0linker.html" >Anti-G4s Linker Antibody</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >ComboX Isotype Controls</a></li> </ul> </div> <div class="pane_box_link"> <h2>Potency Assays</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line - CellInsight</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Pre-clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_d.jpg" alt="Preclinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/L-1788-G4S%C2%A0linker.html" >Anti-G4s Linker Antibody</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Pharmacodynamics Studies</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li><li><a href="/A1904-Organoid-Culture.html" >Organoid Culture Cytokines</a></li> <li><a href="/A1718-Pre-formed-Fibrils-(PFFs).html" >Pre-formed Fibrils (Aneuro)</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix for Organoid Culture</a></li> <li><a href="/A2183-DBC.html" >Diagnostic Biochips</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/P5420-Anti-CD19-%28FMC63%29-CAR-Immunogenicity-ELISA-Kit.html" >Immunogenicity Anti-FMC63 ELISA kit</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Audit & Documentation support</h2> <ul> <li><a href="/A1148-FDA-DMF-Filed-Proteins.html" >FDA DMF Filed Proteins</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html" >GMP Regulatory Support Files</a></li> </ul> </div> <div class="pane_box_link"> <h2>Companion Diagnostics Tools</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_5 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightA_e.jpg" alt="Clinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/L-1788-G4S%C2%A0linker.html" >Anti-G4s Linker Antibody</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1118-mAb-for-Anti-CD19-CAR-Detection-Flow-Cytometry-Validated.html" >Anti-FMC63 Antibody</a></li> <li><a href="/P5420-Anti-CD19-%28FMC63%29-CAR-Immunogenicity-ELISA-Kit.html" >Immunogenicity Anti-FMC63 ELISA kit</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining - Fluorescent Labeled Proteins</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> </ul> </div> </div> </div> </li> </ul> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title upA"> Gene Therapy <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_2"> <div class="layui-menu-body-title layui-menu-body-title2"> Gene Therapy </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_a.jpg" alt="Discovery & Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Gene Editing</h2> <ul> <li><a href="/A1657-CRISPR-Cas-technology.html" >GENPower - Cas Enzymes</a></li> </ul> </div> <div class="pane_box_link"> <h2>AAV Titer Quantitation</h2> <ul> <li><a href="/P7031-AAV5-Titration-ELISA-Kit-%28Fast%29.html" >AAV5 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7157-AAV5-Titration-ELISA-Kit.html" >AAV5 Titration ELISA Kit </a></li> <li><a href="/P7823-AAV3-Titration-ELISA-Kit-%28Fast%29.html" >AAV3 Titration ELISA Kit (Fast) </a></li> <li><a href="/P7100-AAV3-Titration-ELISA-Kit.html" >AAV3 Titration ELISA Kit</a></li> <li><a href="/P7735-AAV8-Titration-ELISA-Kit-%28Fast%29.html" >AAV8 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7736-AAV8-Titration-ELISA-Kit.html" >AAV8 Titration ELISA Kit</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Premium(Pre-GMP) grade Raw Materials</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >Premium(Pre-GMP) Growth Factors</a></li> </ul> </div> <div class="pane_box_link"> <h2>Gene Editing Products</h2> <ul> <li><a href="/A1657-CRISPR-Cas-technology.html" >GENPower - Cas Enzymes</a></li> <li><a href="/A1301-enzyme-products.html#mRNA_enzymeA" >mRNA Synthesis Enzymes</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal Products</h2> <ul> <li><a href="/L-1211-Nuclease.html" >Nucleic Acid Removal</a> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> <div class="pane_box_link"> <h2>AAV Titer Quantitation</h2> <ul> <li><a href="/P7031-AAV5-Titration-ELISA-Kit-%28Fast%29.html" >AAV5 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7157-AAV5-Titration-ELISA-Kit.html" >AAV5 Titration ELISA Kit </a></li> <li><a href="/P7823-AAV3-Titration-ELISA-Kit-%28Fast%29.html" >AAV3 Titration ELISA Kit (Fast) </a></li> <li><a href="/P7100-AAV3-Titration-ELISA-Kit.html" >AAV3 Titration ELISA Kit</a></li> <li><a href="/P7735-AAV8-Titration-ELISA-Kit-%28Fast%29.html" >AAV8 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7736-AAV8-Titration-ELISA-Kit.html" >AAV8 Titration ELISA Kit</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Large-Scale Manufacturing</h2> <ul> <li><a href="/A1751-Key-Raw-Materials-for-Cell-and-Gene-Therapy.html" >GMP-grade Raw Materials</a></li> <li><a href="/A1888-Custom-GMP-Services.html" >GMP Protein Services</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_c.jpg" alt="CMC-Quality Control" width="100%"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" target="_blank" >Residual Host Cell DNA / RNA Detection Kits</a></li> <li><a href="/search-keywords-Activity.html" target="_blank" >RNase / DNase Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" target="_blank" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/P7814-resDetect%E2%84%A2-BSA-ELISA-Kit.html" target="_blank" >Residual BSA ELISA Kit</a></li> <li><a href="/P6991-resDetect%E2%84%A2-Kanamycin-ELISA-Kit.html" target="_blank" >Residual Antibiotics Detection Kits</a></li> <li><a href="/A2504-resDetect-CGT.html" target="_blank" >CGT CMC Manufacturing Process Residue Detection Solutions</a></li> <li><a href="/search-keywords-Mycoplasma.html" target="_blank">Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" target="_blank">Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Potency Assays</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> </ul> </div> <div class="pane_box_link"> <h2>AAV Titer Quantitation</h2> <ul> <li><a href="/P7031-AAV5-Titration-ELISA-Kit-%28Fast%29.html" >AAV5 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7157-AAV5-Titration-ELISA-Kit.html" >AAV5 Titration ELISA Kit </a></li> <li><a href="/P7823-AAV3-Titration-ELISA-Kit-%28Fast%29.html" >AAV3 Titration ELISA Kit (Fast) </a></li> <li><a href="/P7100-AAV3-Titration-ELISA-Kit.html" >AAV3 Titration ELISA Kit</a></li> <li><a href="/P7735-AAV8-Titration-ELISA-Kit-%28Fast%29.html" >AAV8 Titration ELISA Kit (Fast)</a></li> <li><a href="/P7736-AAV8-Titration-ELISA-Kit.html" >AAV8 Titration ELISA Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Pre-clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_d.jpg" alt="Preclinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacodynamics Studies</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li><li><a href="/A1904-Organoid-Culture.html" >Organoid Culture Cytokines</a></li> <li><a href="/A1718-Pre-formed-Fibrils-(PFFs).html" >Pre-formed Fibrils (Aneuro)</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix for Organoid Culture</a></li> <li><a href="/A2183-DBC.html" >Diagnostic Biochips</a></li> </ul> </div> <div class="pane_box_link"> <h2>Security Studies</h2> <ul> <li><a href="/search-keywords-AAV%20antibody%20kit.html" >Anti-AAV Antibody ELISA Kit</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> <div class="pane_box_link"> <h2>Audit & Documentation support</h2> <ul> <li><a href="/A1148-FDA-DMF-Filed-Proteins.html" >FDA DMF Filed Proteins</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html" >GMP Regulatory Support Files</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics Tools</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_5 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightB_e.jpg" alt="Clinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> <div class="pane_box_link"> <h2>Security Studies</h2> <ul> <li><a href="/search-keywords-AAV%20antibody%20kit.html" >Anti-AAV Antibody ELISA Kit</a></li> </ul> </div> </div> </div> </li> </ul> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title upA"> <a href="/A2356-Therapeutic-Antibody-Page.html" >Therapeutic Antibodies </a><i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_3"> <div class="layui-menu-body-title layui-menu-body-title2"> Therapeutic Antibodies </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_a.jpg" alt="Discovery & Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Target Proteins</h2> <ul> <li><a href="/A1288-Cytokine.html" >Cytokine Targets</a></li> <li><a href="/A974-Immune-Checkpoint-Proteins.html" >Checkpoint Proteins</a></li> <li><a href="/A2117-Agonist-Target-Proteins.html" >Agonist</a></li> <li><a href="/A1290-Transmembrane-Proteins-Platform.html" >FLAG</a></li> <li><a href="/A1536-Proteins-for-Neuroscience.html" >Aneuro</a></li> <li><a href="/A1265-Tumor-microenvironment.html" >Tumor Microenvironment</a></li> <li><a href="/A1222-Bispecific-antibody-targets-and-more.html" >Bispecifc Antibody Targets</a></li> <li><a href="/A1656-MHC-Class-I-Complex-Custom-Service.html" >MHC Complexes</a></li> </ul> </div> <div class="pane_box_link"> <h2>Antibody Screening</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1096-Inhibitor-Screening-Kits.html" >Inhibitor Screening Kits</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining Fluorescent Labeled Proteins</a></li> <li><a href="/A1128-Pre-Coupling-Magnetic-Beads.html" >Pre-coupled Magnetic Beads</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1969-Recombinant-Antibody-Services.html" >Recombinant Antibody Expression Services</a></li> <li><a href="/A1151-SPR-BLI-analytical-service.html" >SPR /BLI analytical service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Fc Proteins</h2> <ul> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Fc Proteins</a></li> <li><a href="/A712-Fc-Receptor-Proteins.html" >Fc Receptor</a></li> <li><a href="/A1394-FcRn%EF%BC%88Neonatal-Fc-Receptor%EF%BC%89.html" >Neonatal Fc Receptor</a></li> <li><a href="/P7366-Human-FcRn-binding-Kit-%28TR-FRET%29.html" >FcRn Binding Kit</a></li> </ul> </div> <div class="pane_box_link"> <h2>Cell Line (CellInsight)</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Companion Diagnostics</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal</h2> <ul> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP GENIUS Nuclease</a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_c.jpg" alt="CMC-Quality Control"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" >Host DNA/Protein Quantitative Kits</a></li> <li><a href="/P7433-resDetect%E2%84%A2-Universal-Protein-A-Quick-ELISA-Kit-%28Boiling-free%29.html" >Residual Affinity Ligands Detection Kits</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html#pro" >Residual Cell Culture Materials Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/P6991-resDetect%E2%84%A2-Kanamycin-ELISA-Kit.html" >Residual Antibiotics Detection Kits</a></li> <li><a href="/A2543-resDetect-Antibody.html" >Therapeutic antibodies CMC Manufacturing Process Residue Detection Solutions</a></li> <li><a href="/search-keywords-Mycoplasma.html" >Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" >Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Other Quality Control Products</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Isotype Control</a></li> <li><a href="/A2154-Tool-enzymes.html" >Enzymes for Antibody Characterization Analysis</a></li> <li><a href="/A1794-MALS-UNcle-Platform.html" >Quality Characterization Analytical Services</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cytokine Release Detection</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine ELISA Kits</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Preclinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_d.jpg" alt="Preclinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1089-Anti-idiotypic-Antibodies.html" >Anti-idiotypic Antibodies</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1078-ELISA-Assay-Kits-for-Therapeutic-Antibodies.html" >PK ELISA Assays</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic & ADA Assay Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Pharmacodynamics Studies</h2> <ul> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li><li><a href="/A1904-Organoid-Culture.html" >Organoid Culture Cytokines</a></li> <li><a href="/A1718-Pre-formed-Fibrils-(PFFs).html" >Pre-formed Fibrils (Aneuro)</a></li> <li><a href="/A2145-BME.html" >Mogengel Matrix for Organoid Culture</a></li> <li><a href="/A2183-DBC.html" >Diagnostic Biochips</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Audit & Documentation support</h2> <ul> <li><a href="/A1148-FDA-DMF-Filed-Proteins.html" >FDA DMF Filed Proteins</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html" >GMP Regulatory Support Files</a></li> </ul> </div> <div class="pane_box_link"> <h2>Companion Diagnostics Tools</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_5 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightC_e.jpg" alt="Clinical Studies"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Pharmacokinetics Studies</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1089-Anti-idiotypic-Antibodies.html" >Anti-idiotypic Antibodies</a></li> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody Development Service</a></li> <li><a href="/A1078-ELISA-Assay-Kits-for-Therapeutic-Antibodies.html" >PK ELISA Assays</a></li> <li><a href="/A1326-Enzyme-Linked-Immunosorbent-Assay-%28ELISA%29-Service.html" >PK ELISA Development Service</a></li> </ul> </div> <div class="pane_box_link"> <h2>Immunogenicity Studies</h2> <ul> <li><a href="/A1320-Anti-Idiotypic-Antibody.html" >Anti-idiotypic Antibody ADA Development Service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Toxicity Studies</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine Release Assay Kits - ClinMax</a></li> <li><a href="/search-keywords-Th1/Th2 cytokine.html" >Multiplex Cytokine Assay Kits</a></li> <li><a href="/A2398-Disease-and-human-models.html" >Organoid Toolbox</a></li> </ul> </div> </div> </div> </li> </ul> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title upA"> Antibody Drug Conjugates <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel layui-pane2_1 layui-pane2_1_4"> <div class="layui-menu-body-title layui-menu-body-title2"> Antibody Drug Conjugates </div> <ul> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Discovery and Development <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_1 pane_boxD pane_boxA upA_suow"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightD_a.jpg" alt="Discovery & Development"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Target Proteins</h2> <ul> <li><a href="/A1210-Targets-for-Antibody-Drug-Conjugates.html#module=kit1" >ADC Drug Targets</a></li> <li><a href="/A1288-Cytokine.html" >Cytokine Targets</a></li> <li><a href="/A974-Immune-Checkpoint-Proteins.html" >Checkpoint Proteins</a></li> <li><a href="/A2117-Agonist-Target-Proteins.html" >Agonist</a></li> <li><a href="/A1290-Transmembrane-Proteins-Platform.html" >FLAG</a></li> <li><a href="/A1536-Proteins-for-Neuroscience.html" >Aneuro</a></li> <li><a href="/A1265-Tumor-microenvironment.html" >Tumor Microenvironment</a></li> <li><a href="/A1222-Bispecific-antibody-targets-and-more.html" >Bispecifc Antibody Targets</a></li> <li><a href="/A1656-MHC-Class-I-Complex-Custom-Service.html" >MHC Complexes</a></li> </ul> </div> <div class="pane_box_link"> <h2>Antibody Screening</h2> <ul> <li><a href="/A716-Biotinylated-Protein.html" >Biotinylated Proteins</a></li> <li><a href="/A1096-Inhibitor-Screening-Kits.html" >Inhibitor Screening Kits</a></li> <li><a href="/A1332-Star-Staining-Proteins-Platform.html" >Star Staining Fluorescent Labeled Proteins</a></li> <li><a href="/A1128-Pre-Coupling-Magnetic-Beads.html" >Pre-coupled Magnetic Beads</a></li> <li><a href="/A1670-Streptavidin(SA)-Series-Products.html" >SA series Products ComboX</a></li> <li><a href="/A1969-Recombinant-Antibody-Services.html" >Recombinant Antibody Expression Services</a></li> <li><a href="/A1151-SPR-BLI-analytical-service.html" >SPR /BLI analytical service</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Fc Proteins</h2> <ul> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Fc Proteins</a></li> <li><a href="/A712-Fc-Receptor-Proteins.html" >Fc Receptor</a></li> <li><a href="/A1394-FcRn%EF%BC%88Neonatal-Fc-Receptor%EF%BC%89.html" >Neonatal Fc Receptor</a></li> <li><a href="/P7366-Human-FcRn-binding-Kit-%28TR-FRET%29.html" >FcRn Binding Kit</a></li> </ul> </div> <div class="pane_box_link"> <h2>ADC Reagents</h2> <ul> <li><a href="/A2584-ADC-Conjugation-Kit.html" >AGLink Conjugation Kit</a></li> <li><a href="/A1210-Targets-for-Antibody-Drug-Conjugates.html" >Proteases for Peptide Linker</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cell Line (CellInsight)</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> <div class="pane_box_link"> <h2>Companion Diagnostics</h2> <ul> <li><a href="/A2176-IHC-antibody.html" >IHC Antibodies</a></li> <li><a href="/A2246-Immunohistochemistry-%28IHC%29-Kit.html" >Immunohistochemistry (IHC) Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Manufacturing <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_2 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightD_b.jpg" alt="CMC-Manufacturing"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Nucleic Acid Removal</h2> <ul> <li><a href="/P5787-GMP-GENIUS%E2%84%A2Nuclease-DMF-Filed.html" >GMP GENIUS Nuclease</a></li> <li><a href="/P7181-GMP-Salt-Active-GENIUS%E2%84%A2Nuclease.html" >Salt Active GENIUS™Nuclease</a></li> </ul> </div> <div class="pane_box_link"> <h2>Conjugation Kits</h2> <ul> <li><a href="/A2584-ADC-Conjugation-Kit.html" >AGLink Conjugation Kit</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Quality Control <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_3 pane_boxD"> <div class="pane_box_img"><img width="100%" src="https://www.acrobiosystems.com/static/main/images/HomePhotoA/home_rightD_c.jpg" alt="CMC-Quality Control"></div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Residual Detection-resDetect</h2> <ul> <li><a href="/A2146-Nuclease-Detection-Kits.html" >Host DNA/Protein Quantitative Kits</a></li> <li><a href="/P7433-resDetect%E2%84%A2-Universal-Protein-A-Quick-ELISA-Kit-%28Boiling-free%29.html" >Residual Affinity Ligands Detection Kits</a></li> <li><a href="/A1557-GMP-Grade-Cytokines.html#pro" >Residual Cell Culture Materials Detection Kits</a></li> <li><a href="/P7571-resDetect%E2%84%A2-GENIUS%E2%84%A2-Nuclease-ELISA-Kit-%28Residue-Testing%29.html" >GENIUS™ Nuclease Residual Detection Kit</a></li> <li><a href="/search-keywords-Mycoplasma.html" >Mycoplasma Rapid Detection Kit</a></li> <li><a href="/P7954-Recombinant-Factor-C-Endotoxin-Detection-Kit.html" >Recombinant Factor C Endotoxin Detection Kit</a></li> <li><a href="https://www.acrobiosystems.com/A2331-resDetect.html" >More >></a></li> </ul> </div> <div class="pane_box_link"> <h2>Other Quality Control Products</h2> <ul> <li><a href="/A2221-Stable-cell-line.html" >Overexpression cell line</a></li> <li><a href="/A1391-IgG-Fc-Proteins%E2%80%94%E2%80%94Ideal-Isotype-Control-for-IgG-Structured-Drug-Development.html" >IgG Isotype Control</a></li> <li><a href="/A2154-Tool-enzymes.html" >Enzymes for Antibody Characterization Analysis</a></li> <li><a href="/A1794-MALS-UNcle-Platform.html" >Quality Characterization Analytical Services</a></li> <li><a href="/A2219-Cell-Line-Customize-Service.html" >Cell Line Customization services</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>ADC Payload Evaluation</h2> <ul> <li><a href="/A2226-Anti-payload-antibodies.html" >Anti-payload Antibodies</a></li> </ul> </div> <div class="pane_box_link"> <h2>Antibody Enzymes</h2> <ul> <li><a href="/A1301-enzyme-products.html" >Antibody Characterization</a></li> </ul> </div> </div> <div class="layui-col-md12"> <div class="pane_box_link"> <h2>Cytokine Release Detection</h2> <ul> <li><a href="/A1781-Cytokine-detection-ELISA-kits.html" >Cytokine ELISA Kits</a></li> </ul> </div> </div> </div> </li> <li class="layui-menu-item-parent" lay-options="{type: 'parent'}"> <div class="layui-menu-body-title"> Pre-clinical Research <i class="layui-icon layui-icon-right"></i> </div> <div class="layui-menu-body-panel pane_box pane_box2_4 pane_boxD"> <div class="pane_box_img"><img width="100%" 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One of the most widely studied TCBs in cancer immunotherapy is CD3, a molecule that has the function of stabilizing TCR structure and transmitting activation signals.</p><p class="public_text_dec" style="margin-bottom:10px;">Antibodies against CD3 molecules can stimulate or block T cell activation signal transduction. In addition, these antibodies can eliminate effector T cells or induce a regulatory phenotype in T cells thus, providing a new method for the treatment of organ transplant rejection and autoimmune diseases. These CD3 molecules bind to TCR non-covalently to form a TCR/CD3 receptor complex on the surface of the T cell.</p><div class="layui-row"><div class="layui-col-md4"><img src="/static/main/images/cd3/cd3_2.jpg" width="391" align="left"/></div><div class="layui-col-md8"><p class="text_photo_right public_text_dec" style="margin-bottom:10px;">There are 4 subtypes of CD3, including CD3δ, CD3ε, CD3γ, and CD3ζ. CD3δ/CD3ε and CD3γ/CD3ε can form the TCR-CD3 complexes through the α/β chain of TCR as heterodimers. CD3-targeted therapeutic antibody usually recognizes the CD3ε in the heterodimer complex to activate the anti-tumor activity of T cells. However, in the process of recombinant expression, CD3ε and CD3δ can randomly form incorrect heterogeneous complexes, which may lead to the loss of bioactivity and high batch-to-batch inconsistency.</p><p style="margin-bottom:10px;" class="public_text_dec">To accelerate the research and development of bispecific antibodies, ACROBiosystems has developed a series of homogeneous CD3δ/CD3ε and CD3γ/CD3ε proteins with high bioactivity. These proteins are verified as a 1:1 heterodimer by nonreductive electrophoresis and MALS respectively. In addition, customer data suggests that bispecific antibody products from ACROBiosystems can be used in applications including, but not limited to clinical pharmacokinetics, therapeutic antibody screening, identification, and characterization.</p><p class="public_text_dec">Successively, our superior CD3 product quality helped accelerate the clinical development of a bispecific antibody into a therapeutic. <a href="https://drive.google.com/file/d/1spPYUPSTdyUoViVI8lx897FBJ6SRGpzu/view?usp=sharing" id="poster" target="_blank" style="color: #cc3536; text-decoration:underline; font-weight:bold;"> Click here to download CD3 poster.<img src="/static/main/hand.png" style="width: 24px;margin-top: 16px;"/></a></p></div></div></div><div class="productSection"><div class="productTit" style="margin-top: 20px">Product Features</div><div class="s-con cf"><div class="layui-col-space10 " style="float: left;width: 100%;"><div class="layui-col-md6"><p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20"/><strong>Larger product catalog</strong></p><table width="100%" border="0"><tbody><tr class="firstRow"><td valign="top"><p><span style="color:#cc3536;">5 molecules: </span>CD3ε& CD3δ, CD3ε& CD3γ, CD3ε, CD3δ, CD3γ</p></td></tr><tr><td valign="top"><p><span style="color:#cc3536;">Various tags: </span>His, His&Avi, Fc, Llama Fc, Flag</p></td></tr><tr><td valign="top"><p><span style="color:#cc3536;">Various species: </span>Human, Mouse, Cynomolgus, Rat, Rabbit</p></td></tr></tbody></table><p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20"/><strong style="color:#cc3536;">Homogeneous structure: </strong>CD3ε& CD3δ and CD3ε& CD3γ are verified as 1:1 heterodimers by non-reductive electrophoresis and MALS</p></div><div class="layui-col-md6"><p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20"/><strong style="color:#cc3536;">High bioactivity </strong>verified by binding with common antibodies such as OKT3, SP34-2, UCHT1 and BCMA×CD3</p><p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20"/><strong style="color:#cc3536;">High batch-to-batch consistency </strong>guaranteed by strict quality control</p><p><img src="/static/main/images/mutants/pentagram1.png" style="margin-right:10px; margin-top:-4px;" width="20"/><strong style="color:#cc3536;">Suitable for different applications </strong>including antibody immunotiter detection, biopanning, antibody screening, affinity characterization and clinical pharmacokinetic assay</p></div></div></div></div><div class="productSection" id="pro"><div class="productTit" style="margin-top: 20px;">Product List</div><div class="layui-tab layui-tab-card" lay-filter="module"><ul class="layui-tab-title list-paddingleft-2"><li class="layui-this" lay-id="kit1" id="kit1"><p>CD3E & CD3D</p></li><li lay-id="kit2" id="kit2"><p>CD3E & CD3G</p></li><li lay-id="kit3" id="kit3"><p>CD3 epsilon</p></li><li lay-id="kit4" id="kit4"><p>CD3 delta</p></li><li lay-id="kit5" id="kit5"><p>CD3 gamma</p></li></ul><div class="layui-tab-content"><div class="layui-tab-item layui-show"><table class="public_table layui-table pro_table pro_table_box"><thead><tr class="firstRow" style="font-weight:bolder"><th style="width: 120px">Molecule</th><th style="width: 120px">Cat. No.</th><th>Host</th><th>Product Description</th><th>Structure</th></tr></thead><tbody id="product_list_94"></tbody></table></div><div class="layui-tab-item"><table class="public_table layui-table pro_table pro_table_box"><thead><tr class="firstRow" style="font-weight:bolder"><th style="width: 120px">Molecule</th><th style="width: 120px">Cat. No.</th><th>Host</th><th>Product Description</th><th>Structure</th></tr></thead><tbody id="product_list_823"></tbody></table></div><div class="layui-tab-item"><table class="public_table layui-table pro_table pro_table_box"><thead><tr class="firstRow" style="font-weight:bolder"><th style="width: 120px">Molecule</th><th style="width: 120px">Cat. No.</th><th>Host</th><th>Product Description</th><th>Structure</th></tr></thead><tbody id="product_list_93"></tbody></table></div><div class="layui-tab-item"><table class="public_table layui-table pro_table pro_table_box"><thead><tr class="firstRow" style="font-weight:bolder"><th style="width: 120px">Molecule</th><th style="width: 120px">Cat. No.</th><th>Host</th><th>Product Description</th><th>Structure</th></tr></thead><tbody id="product_list_92"></tbody></table></div><div class="layui-tab-item"><table class="public_table layui-table pro_table pro_table_box"><thead><tr class="firstRow" style="font-weight:bolder"><th style="width: 120px">Molecule</th><th style="width: 120px">Cat. No.</th><th>Host</th><th>Product Description</th><th>Structure</th></tr></thead><tbody id="product_list_787"></tbody></table></div></div></div><div class="clear"></div><div class="cd20ProtocolTitle" id="pro_more"><div class="h4-title">More BsAb targets</div></div><div class="clear"></div><p>Click the molecule to find out your interesting products.</p><div class="clear"></div><div class="productList" style="margin-bottom:20px;"><a href="/L-69-CD19.html" target="_blank">CD19</a><a href="/L-965-CD20.html" target="_blank">CD20</a><a href="/L-91-CD38.html" target="_blank">CD38</a><a href="/L-96-CD40.html" target="_blank">CD40</a><a href="/L-100-CD47.html" target="_blank">CD47</a><a href="/L-895-IL-3 R alpha.html" target="_blank">IL-3 R alpha</a><a href="/L-266-Her2.html" target="_blank">Her2</a><a href="/L-201-ErbB3.html" target="_blank">ErbB3</a><a href="/L-349-LAG-3.html" target="_blank">LAG-3</a><a href="/L-2-4-1BB.html" target="_blank">4-1BB</a><a href="/L-404-PD-1.html" target="_blank">PD-1</a><a href="/L-408-PD-L1.html" target="_blank">PD-L1</a><a href="/L-161-CTLA-4.html" target="_blank">CTLA-4</a><a href="/L-493-TIM-3.html" target="_blank">TIM-3</a><a href="/L-195-EpCAM.html" target="_blank">EpCAM</a><a href="/L-192-EGF R.html" target="_blank">EGF R</a><a href="/L-36-BCMA.html" target="_blank">BCMA</a><a href="/L-229-PSMA.html" target="_blank">PSMA</a><a href="/L-142-HGF R.html" target="_blank">HGF R</a><a href="/L-432-ROR1.html" target="_blank">ROR1</a><a href="/L-336-VEGF R2.html" target="_blank">VEGF R2</a><a href="/L-1055-FAP.html" target="_blank">FAP</a><a href="/L-293-IL-1 beta.html" target="_blank">IL-1 beta</a><a href="/L-323-IL-4.html" target="_blank">IL-4</a><a href="/L-327-IL-6 R alpha.html" target="_blank">IL-6 R alpha</a><a href="/L-537-IL-13.html" target="_blank">IL-13</a><a href="/L-805-IL-17A.html" target="_blank">IL-17A</a><a href="/L-873-Fc gamma RIII / CD16.html" target="_blank">CD16</a><a href="/L-497-TNF-alpha.html" target="_blank">TNF-alpha</a><a href="/L-16-Angiopoietin-2.html" target="_blank">ANGTP2</a><a href="/L-400-OX40.html" target="_blank">OX40</a><a href="/L-753-ICOS.html" target="_blank">ICOS</a><a href="/L-977-HGF.html" target="_blank">HGF</a><a href="/L-811-B7-H3.html" target="_blank">B7-H3</a><a href="/L-486-TGF-beta%201.html" target="_blank">TGF-beta 1 </a><a href="/L-967-LRP-5.html" target="_blank">LRP-5</a><a href="/L-966-LRP-6.html" id="service" target="_blank">LRP-6</a><a href="/L-913-CEACAM-5.html" target="_blank">CEACAM-5</a><a href="/L-380-Mucin-1.html" target="_blank">Mucin-1</a><a href="/L-889-DLL3.html" target="_blank">DLL3</a></div><div class="clear"></div></div><div class="clear"></div><div class="productSection"><div class="productTit">Bioanalytical assay development service</div><p class="public_text_dec" style="margin-bottom:10px;">CD3-targeted bispecific and trispecific antibodies represent a fast-growing field in therapeutic antibody development. However, selecting the appropriate detection reagents for custom bioanalytical assays such as ELISAs is challenging. With an abundant selection of CD3 proteins including labels and tags, companies may struggle in developing a highly sensitive and specific assay for their drug therapy.</p><p class="public_text_dec" style="margin-bottom:10px;">Here at ACROBiosystems, we can provide a large product catalog of highly bioactive CD3δ/CD3ε, CD3γ/CD3ε products as well as our expertise and our ISO17025-accedited analytical service platform. Using our analytical service platform, we offer customized services from paired protein screening to ELISA-based assay release method development, validation, and kit development to help accelerate your R&D process!</p><h3 class="h3-title">Case Studies</h3><div class="public_img_text_box public_img_l_r layui-col-space10 productSPR" style="float: left"><div class="layui-col-md6" style="padding: 20px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_1010_1.jpg"/></div><p class="imgText"><em>Immobilized Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. <a target="_blank" href="/P4122-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-Fc-TagFc-Tag-(MALS-verified).html">CDD-H5255</a>) at 1 μg/mL (100 μL/well) was spiked with different concentrations of bispecific BCMA×CD3 T cell-engaging Antibody. The identified linear range was found to be 0.8-6 ng/mL. <br/><br/><br/></em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H5255">Protocol</a></label></center></div><div class="layui-col-md6" style="padding: 20px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_1010_2.jpg"/></div><p class="imgText" id="p4"><em>Immobilized Human BCMA, His Tag (Cat. No. <a target="_blank" href="/P2187-Human-BCMA--TNFRSF17-ProteinHis-Tag-(HPLC-verified)-DMF-Filed.html">BCA-H522y</a>) was bound to a 96-well plate. Increasing concentrations of bispecific T cell Engager (CD3 X BCMA) spiked in 10% human serum and Biotinylated Human CD3E&3D Heterodimer Protein, His,Avitag&Tag Free (Cat. No. <a href="/P3248-Biotinylated-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-HisAvitag™Tag-Free-(MALS-verified).html" target="_blank">CDD-H82W6</a>) at 0.2 μg/mL was added to each well. Detection was performed using HRP-conjugated streptavidin with sensitivity of 15 ng/mL.</em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="BCA-H522y">Protocol</a></label></center></div></div><div class="clear"></div><div class="solution_content"><p class="imga" style="text-align:center;"><img src="/static/main/images/cd3/cd3_1010_3.jpg"/></p><p class="fc_Solution"><strong id="hot">Flexible assay designs and report formats for your personalized needs<br/>ACRO proteins are supplied for free<br/>Only samples are required for service completion</strong></p></div><div class="clear"></div><div style="width:100%;float:left; margin-top:20px; margin-bottom:20px;"><center><div class="other_que" name="platforms"><div class="otherQuestions"><div class="questionsCon"><h4>Inquiry and order</h4><ul class=" list-paddingleft-2"><li><p>ACROBiosystems scientist will respond within 24 hours of submission.</p></li><li><p style="margin-bottom: 0px;">Call us at: +1 800-810-0816 or email at <a style="color:#cc3536; font-weight:bold;" href="mailto:services@acrobiosystems.com">services@acrobiosystems.com</a> for consultation.</p></li></ul></div><div class="questionsConright"><a target="_blank" href="/A1300-Form-SPR-BLI-service-.html?service=ELISA service" class="Contact-btn">SPEAK TO A SCIENTIST</a></div></div></div></center></div></div><div class="productSection"><div class="productTit" id="p1">Data</div><h3 class="h3-title">1:1 heterodimer verified by nonreductive electrophoresis and MALS</h3><p>ACROBiosystems has developed a series of homogeneous CD3 proteins with good bioactivity, which are verified as 1:1 heterodimer by nonreductive electrophoresis and MALS.</p><div class="product_typical"><dl class="layui-col-md12"><dt><br/><img src="/static/main/images/cd3/cd3_22.jpg" style="max-width: 800px"/></dt><dd class="layui-col-md8"><p><em>Fig.1 Human CD3E&CD3D Heterodimer Protein (Cat. No. <a href="/P4010-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-FcHis-TagFcFlag-Tag-%28MALS-verified%29.html" target="_blank">CDD-H52Wa</a>) on SDS-PAGE under reducing (R) and non-reducing（NR）condition and the purity of the protein is greater than 95%. The purity of the protein is more than 85% and around 80-90 kDa verified by SEC-MALS.</em></p></dd><dt id="p2"><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H52Wa">Protocol</a></label></center></dt></dl></div><div class="clear"></div><h3 class="h3-title">High binding ability and low batch-to-batch differences</h3><p>These verified authentic 1:1 heterodimer proteins show high bioactivity in different applications. The products are homogenous with strict quality control to guarantee the minimal batch-to-batch differences.</p><div class="product_typical"><dl class="layui-col-md12"><dt><br/><img src="/static/main/images/cd3/cd3_4.jpg" style="max-width: 500px"/></dt><dd class="layui-col-md8"><p><em>Fig.2 Immobilized Biotinylated Human CD3E&CD3D Heterodimer Protein, His,Avitag&Tag Free (Cat. No. <a href="/P3248-Biotinylated-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-HisAvitagTag-Free-%28MALS-verified%29.html" target="_blank">CDD-H82W6</a>) at 1 μg/mL (100 μL/well) on Streptavidin (Cat. No. <a href="/P3198-Recombinant-Streptavidin.html" target="_blank">STN-N5116</a>) precoated (0.5 μg/well) plate, can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a  (Cat. No. CDE-M120a) with a linear range of 0.2-6 ng/mL (QC tested), and batch differences EC50<0.0001 μg/mL.</em></p></dd><dt id="p3"><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H82W6">Protocol</a></label></center></dt></dl></div><div class="clear"></div><h3 class="h3-title">Designed for different applications of drug development</h3><p>These products are suitable for various applications at different stages of drug development, such as antibody immunotiter detection, biopanning, antibody screening, affinity characterization and clinical pharmacokinetic assays.</p><div class="cd20ProtocolTitle"><div class="h4-title">Application 1: Development and screening of antibody drugs</div></div><div class="public_img_text_box public_img_l_r layui-col-space10 productSPR" style="float: left"><div class="layui-col-md6" style="padding: 30px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_5.jpg"/></div><p class="imgText"><em>Fig.3 Immobilized Biotinylated Human CD3E&CD3D Heterodimer Protein, His,Avitag&Tag Free (Cat. No. <a href="/P3248-Biotinylated-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-HisAvitagTag-Free-%28MALS-verified%29.html" target="_blank">CDD-H82W6</a>) at 1 μg/mL (100 μL/well) on streptavidin precoated (0.5 μg/well) plate, can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a  (Cat. No. CDE-M120a) with a linear range of 0.2-6 ng/mL.</em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H82W6">Protocol</a></label></center></div><div class="layui-col-md6" style="padding: 30px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_6.jpg"/></div><p class="imgText" id="p4"><em>Fig.4 Immobilized Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (Cat. No. <a href="/P3220-Human-CD3-epsilon--CD3-delta-Heterodimer-Protein-His-TagTag-Free-%28MALS-verified%29.html" target="_blank">CDD-H52W1</a>) at 1 μg/mL (100 μL/well) can bind Anti-CD3 antibody with a linear range of 0.2-6 ng/mL.<br/><br/><br/></em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H52W1">Protocol</a></label></center></div></div><div class="cd20ProtocolTitle"><div class="h4-title">Application 2: Identification and quality control of antibody drugs</div></div><div class="public_img_text_box public_img_l_r layui-col-space10 productSPR" style="float: left"><div class="layui-col-md6" style="padding: 30px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_7.jpg"/></div><p class="imgText"><em>Fig.5 Immobilized Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (Cat. No. <a href="/P3220-Human-CD3-epsilon--CD3-delta-Heterodimer-Protein-His-TagTag-Free-%28MALS-verified%29.html" target="_blank">CDD-H52W1</a>) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human CD3 Antibody, Mouse IgG2a  (Cat. No. CDE-M120a) with a linear range of 0.2-6 ng/mL.<br/></em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H52W1">Protocol</a></label></center></div><div class="layui-col-md6" style="padding: 30px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_12.jpg"/></div><p class="imgText" id="p5"><em>Fig.6 Immobilized Human CD3E&CD3D Heterodimer Protein, Fc Tag&Fc Tag (Cat. No. <a href="/P4122-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-Fc-TagFc-Tag-%28MALS-verified%29.html" target="_blank">CDD-H5255</a>) at 1 μg/mL (100 μL/well) can bind Bispecific BCMA×CD3 T cell-engaging Antibody with a linear range of 0.8-6 ng/mL.<br/></em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H5255">Protocol</a></label></center></div></div><div class="public_img_text_box public_img_l_r layui-col-space10 productSPR" style="float: left"><div class="layui-col-md6" style="padding: 30px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_9.jpg"/></div><p class="imgText"><em>Fig.7 Biotinylated Human CD3E&CD3D Heterodimer Protein, His,Avitag&Tag Free (Cat. No. <a href="/P3248-Biotinylated-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-HisAvitagTag-Free-%28MALS-verified%29.html" target="_blank">CDD-H82W6</a>) captured on Biotin CAP - Series S sensor Chip can bind Anti-Human CD3 Antibody, Mouse IgG2a  with an affinity constant of 22.5 nM as determined in a SPR assay (Biacore T200) .</em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H82W6">Protocol</a></label></center></div><div class="layui-col-md6" style="padding: 30px;"><div class="imgBox"><img alt="" src="/static/main/images/cd3/cd3_10.jpg"/></div><p class="imgText" id="p6"><em>Fig.8 Bispecific T-cell Engager (CD3 X BCMA) immobilized on CM5 Chip can bind Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (Cat. No. <a href="/P3220-Human-CD3-epsilon--CD3-delta-Heterodimer-Protein-His-TagTag-Free-%28MALS-verified%29.html" target="_blank">CDD-H52W1</a>) with an affinity constant of 31.8 nM as determined in a SPR assay (Biacore T200).</em></p><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="CDD-H52W1">Protocol</a></label></center></div></div><div class="cd20ProtocolTitle" id="features3"><div class="h4-title">Application 3: Clinical PK assay</div></div><div class="product_typical"><dl class="layui-col-md12"><dt><img src="/static/main/images/cd3/cd3_11.jpg"/></dt><dd class="layui-col-md8"><p><em>Fig.9 Immobilized Human BCMA, His Tag (Cat. No. <a href="/P2187-Human-BCMA--TNFRSF17--CD269-Protein-His-Tag.html" target="_blank">BCA-H522y</a>) at 2 μg/mL, add increasing concentrations of Bispecific T cell Engager (CD3 X BCMA) in 10% human serum and then add Biotinylated Human CD3E&CD3D Heterodimer Protein, His,Avitag&Tag Free (Cat. No. <a href="/P3248-Biotinylated-Human-CD3-epsilonCD3-delta-Heterodimer-Protein-HisAvitagTag-Free-%28MALS-verified%29.html" target="_blank">CDD-H82W6</a>) at 0.2 μg/mL. Detection was performed using HRP-conjugated streptavidin with sensitivity of 15 ng/mL.</em></p></dd><dt><center><label class="btn_protocol des_protocol"><a style="color:#FFFFFF" data-sign="BCA-H522y">Protocol</a></label></center></dt></dl></div><div class="clear"></div></div><div id="sup_tip"><a href="https://academic.oup.com/abt/article/3/1/18/5739255" target="_blank" style="color: #cc3536;text-decoration: underline;">[1] Siwei N , Zhuozhi W , Maria M C , et al. Biology drives the discovery of bispecific antibodies as innovative therapeutics[J]. 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embedded_svc.settings.displayHelpButton = true; embedded_svc.settings.language = 'en'; embedded_svc.settings.defaultMinimizedText = 'Online - Welcome to ACROBiosystems'; embedded_svc.settings.disabledMinimizedText = 'Offline - Leave a message'; embedded_svc.settings.loadingText = 'Online - Welcome to ACROBiosystems'; embedded_svc.settings.prepopulatedPrechatFields = { FirstName: onlineChatuserInfo.firstName, LastName: onlineChatuserInfo.lastName, Email: onlineChatuserInfo.email, Company_Name__c: onlineChatuserInfo.company, Question_Type__c:'', Phone: onlineChatuserInfo.phone, }; // 将联系人字段赋值给会话 embedded_svc.settings.extraPrechatFormDetails = [ {"label":"Question Type", "transcriptFields": ["Question_Type__c"]}, {"label":"Company Name", "transcriptFields": ["Contact_Company_Name__c"]}, {"label":"Phone", "transcriptFields": ["Contact_Phone__c"]}, {"label": "Source URL","value": window.location.href,"displayToAgent": true,"transcriptFields" : ["RequstURL__c"]} ]; embedded_svc.settings.widgetWidth = "320px"; embedded_svc.settings.widgetHeight = "498px"; embedded_svc.settings.directToButtonRouting = function(prechatFormData) { if (prechatFormData[4].value === "Technical") return "573A9000000002L"; if (prechatFormData[4].value === "Service") return "573A9000000002L"; if (prechatFormData[4].value === "Non-technical") return "573A9000000002Q"; } embedded_svc.settings.enabledFeatures = ['LiveAgent']; embedded_svc.settings.entryFeature = 'LiveAgent'; embedded_svc.init( 'https://d7f000005vpftua0.my.salesforce.com', 'https://d7f000005vpftua0.my.salesforce-sites.com/acrobiosystems', gslbBaseURL, '00D7F000005VpFT', 'Acrolive', { baseLiveAgentContentURL: 'https://c.la1-core1.sfdc-mchho0.salesforceliveagent.com/content', deploymentId: '572A9000000001X', buttonId: '573A9000000002Q', baseLiveAgentURL: 'https://d.la1-core1.sfdc-mchho0.salesforceliveagent.com/chat', eswLiveAgentDevName: 'EmbeddedServiceLiveAgent_Parent04IA9000000000pMAA_18792d6e3fc', isOfflineSupportEnabled: false } ); }; const onlineChatuserInfo = {firstName:'', lastName: '', email: document.getElementById("auto_user_email").value, company:document.getElementById("auto_user_company").value, phone: document.getElementById("auto_user_mobile").value}; if (!window.embedded_svc) { var s = document.createElement('script'); s.setAttribute('src', 'https://d7f000005vpftua0.my.salesforce.com/embeddedservice/5.0/esw.min.js'); s.onload = function() { initESW(null, onlineChatuserInfo); }; document.body.appendChild(s); } else { initESW('https://service.force.com', onlineChatuserInfo); } </script> <script type="text/javascript"> var loadInit = self.setInterval("loadInput()", 300); var loadInit2 = self.setInterval("loadInput2()", 300); function loadInput2() { var comdiv = document.getElementsByClassName("showDockableContainer")[0]; var sidebar = document.getElementsByClassName("sidebarBody")[0]; if (comdiv != undefined) { // 弹窗 Header var buttonElement = document.querySelector( "[c-preChatHeaderLWC_preChatHeaderLWC-host]" ); // 鼠标形状是小手 if(buttonElement != undefined){ buttonElement.style.cursor ='pointer'; } if(comdiv.style.width == "320px"){ sidebar.style.width = "318px" } var dismaxbuttonId = ''; var minbuttonId = ''; if( dismaxbuttonId == '' || minbuttonId == ''){ for(var i = 0;i < 100;i++){ var indexNo = i == 0?'1':i+'1'; 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var x = e.clientX - spaceX; // 移动弹窗时左右限制 if(x <0){ x=0; } else if(x > clientwidth - comdiv.offsetWidth){ x = clientwidth - comdiv.offsetWidth; } // 移动弹窗时上下限制 var y = e.clientY - spaceY; if(y <0){ y=0; } else if(y >clientHeight -comdiv.offsetHeight){ y = clientHeight -comdiv.offsetHeight; } comdiv.style.left = x + "px"; comdiv.style.top = y + "px"; }; e.preventDefault(); }; //松开下login_title区域，为整个网页文档解绑鼠标移动事件 buttonElement.onmouseup = function (evn) { evn.preventDefault(); buttonElement.onmousemove = null; document.onmousemove = null; }; } } if(comdiv != undefined){ // 定义4个变量 var disX = 0;//鼠标按下时光标的X值 var disY = 0;//鼠标按下时光标的Y值 var disW = 0; //拖拽前div的宽 var disH = 0; // 拖拽前div的高 //3. 给小div加点击事件 comdiv.onmouseover = function (evs) { var evs = evs || window.event; var offsetLeft = comdiv.offsetLeft; var getfoc = Math.abs(evs.clientX - (parseInt(offsetLeft)+comdiv.offsetWidth)); console.log('getfoc====>'+getfoc); if( getfoc == 1 || getfoc == 2 ){ comdiv.style.cursor ='col-resize'; document.onmousedown = function (ev) { var ev = ev || window.event; 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inputValue=inputUse.value; showUse.innerHTML=''; showUse.style.display='none'; inputUse.focus(); $("#search-history").click(); }; var aFocus = function(){ for(var i=len; i>=0; i--){ if(this.parentNode===select.childNodes[i].childNodes[0]){ current = i; break; } } for(var k in elemCSS.focus){ this.style[k] = elemCSS.focus[k]; } }; var aBlur= function(){ for(var k in elemCSS.blur) this.style[k] = elemCSS.blur[k]; }; var aKeydown = function(event){ event = event || window.event; if(event.keyCode===9){ showUse.innerHTML=''; showUse.style.display = 'none'; inputUse.focus(); } else if(event.keyCode==40){ current++; if(current>len){ current=-1; inputUse.focus(); }else{ select.getElementsByTagName('a')[current].focus(); } } else if(event.keyCode==38){ current--; if(current<0){ inputUse.focus(); }else{ select.getElementsByTagName('a')[current].focus(); } } }; for(var i=0; i<aArray.length; i++){ aArray[i].onclick = aClick; aArray[i].onfocus = aFocus; aArray[i].onblur = aBlur; aArray[i].onkeydown = aKeydown; } } </script> <script> function getCookie(name) { var nameEQ = name + "="; var ca = document.cookie.split(';'); for(var i=0;i < ca.length;i++) { var c = ca[i]; while (c.charAt(0)==' ') { c = c.substring(1,c.length); } if (c.indexOf(nameEQ) == 0) { return unescape(c.substring(nameEQ.length,c.length)); } } return ''; } function clearCookie(name) { setCookie(name, "", -1); } function setCookie(name, value, seconds) { seconds = seconds || 0; var expires = ""; if (seconds != 0 ) { var date = new Date(); date.setTime(date.getTime()+(seconds*1000)); expires = "; expires="+date.toGMTString(); } document.cookie = name+"="+escape(value)+expires+"; path=/"; } </script> <script type="text/javascript" src="/static/main/js/referrer_source.js"></script> <script> setCookie('user_from_region', '亚太区'); setCookie('user_from_country', 'Singapore'); </script> <script> $(function () { //存储进入网站的上一页链接 if(document.cookie.indexOf("zfx_referrer=") == -1){ setCookie("zfx_referrer",decodeURI(document.referrer),1800); } //存储进入网站的上一页链接 END //google $(".newLoginSubmit").click(function () { var email = $(this).parents('form').find("#email").val(); var label = email == "" ? 'login' : email; gtag('event', 'click', { 'event_category': 'userLogin', 'event_label': label }); }) $(".newRegSubmit").click(function () { var email = $(this).parents('form').find("#email").val(); var label = email == "" ? 'register' : email; gtag('event', 'click', { 'event_category': 'userRegister', 'event_label': label }); }) //导航条点击 $(".nav a").click(function () { var label = $(this).html(); gtag('event', 'click', { 'event_category': 'webNav', 'event_label': label }); }) //底部图标点击 $(".google_icon a").click(function () { var label = $(this).attr('href'); gtag('event', 'click', { 'event_category': 'commonFooterIcon', 'event_label': label }); }) //google }) </script> <script src="//cbe.huiju.cool/cbe/collect?tid=105249838&at=0&h=web"></script> <script> huiju_tag = typeof(huiju_tag) == 'undefined' || huiju_tag == "" ? 'other' : huiju_tag; var url = window.location.pathname; var url_arr = url.match(/\/([A|L][0-9]{1,10})-/); huiju_tag = url_arr != null ? url_arr[1] : huiju_tag; try{ clab_tracker.ready(function(){ const s = { source: getCookie("zfx_utm_source"), source1: getCookie('zfx_utm_medium'), source8: getCookie('zfx_utm_term'), contentName: getCookie('zfx_utm_content'), source7: getCookie('zfx_utm_campaign') }; this.push(s); if(Request.cid) this.push({customerId: Request.cid}); this.push({"pageType":"web"}); this.track("open_page", { tag: huiju_tag, identityType: 'email', identityValue: $("#auto_user_email").val() }); }); } catch (e) { var clab_tracker = {push: function() {}, track: function() {}} } function getFormatDate(){ var nowDate = new Date(); var year = nowDate.getFullYear(); var month = nowDate.getMonth() + 1 < 10 ? "0" + (nowDate.getMonth() + 1) : nowDate.getMonth() + 1; var date = nowDate.getDate() < 10 ? "0" + nowDate.getDate() : nowDate.getDate(); var hour = nowDate.getHours()< 10 ? "0" + nowDate.getHours() : nowDate.getHours(); var minute = nowDate.getMinutes()< 10 ? "0" + nowDate.getMinutes() : nowDate.getMinutes(); var second = nowDate.getSeconds()< 10 ? "0" + nowDate.getSeconds() : nowDate.getSeconds(); return year + "-" + month + "-" + date+" "+hour+":"+minute+":"+second; } </script> <script type="text/javascript" src="//s7.addthis.com/js/300/addthis_widget.js#pubid=ra-5e4c92a56435a9d4"></script> </body> </html>

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CD3 Protein - A hot target for bispecific antibody - ACROBiosystems