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Emily's Entourage » My Experience with Phage Therapy: 3 Years Later
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overflow: hidden; background-size: cover; overflow: hidden; right: 0; border-left-style: solid; border-left-color: #212121; border-left-width: 1px; height: 40px; width: 40px; color: #ffffff; background-color: #212121; } #rmp-menu-wrap-16555 .rmp-menu-subarrow svg { fill: #ffffff; } #rmp-menu-wrap-16555 .rmp-menu-subarrow:hover { color: #ffffff; border-color: #3f3f3f; background-color: #3f3f3f; } #rmp-menu-wrap-16555 .rmp-menu-subarrow:hover svg { fill: #ffffff; } #rmp-menu-wrap-16555 .rmp-menu-subarrow .rmp-font-icon { margin-right: unset; } #rmp-menu-wrap-16555 .rmp-menu-subarrow * { vertical-align: middle; line-height: 40px; } #rmp-menu-wrap-16555 .rmp-menu-subarrow-active { display: block; background-size: cover; color: #ffffff; border-color: #212121; background-color: #212121; } #rmp-menu-wrap-16555 .rmp-menu-subarrow-active svg { fill: #ffffff; } #rmp-menu-wrap-16555 .rmp-menu-subarrow-active:hover { color: #ffffff; border-color: #3f3f3f; background-color: #3f3f3f; } #rmp-menu-wrap-16555 .rmp-menu-subarrow-active:hover svg { fill: #ffffff; } #rmp-menu-wrap-16555 .rmp-submenu { display: none; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-item-link { height: 40px; line-height: 40px; letter-spacing: 0px; font-size: 13px; border-bottom: 1px solid #3f3f3f; font-family: inherit; font-weight: normal; color: #ffffff; text-align: left; background-color: #474747; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-item-link:hover, #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-item-link:focus { color: #ffffff; border-color: #3f3f3f; background-color: #3f3f3f; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-current-item .rmp-menu-item-link { color: #ffffff; border-color: #3f3f3f; background-color: #3f3f3f; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-current-item .rmp-menu-item-link:hover, #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-current-item .rmp-menu-item-link:focus { color: #ffffff; border-color: #3f3f3f; background-color: #3f3f3f; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-subarrow { right: 0; border-right: unset; border-left-style: solid; border-left-color: #1d4354; border-left-width: 0px; height: 39px; line-height: 39px; width: 40px; color: #fff; background-color: inherit; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-subarrow:hover { color: #fff; border-color: #3f3f3f; background-color: inherit; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-subarrow-active { color: #fff; border-color: #1d4354; background-color: inherit; } #rmp-menu-wrap-16555 .rmp-submenu .rmp-menu-subarrow-active:hover { color: #fff; border-color: #3f3f3f; background-color: inherit; } #rmp-menu-wrap-16555 .rmp-menu-item-description { margin: 0; padding: 5px 5%; opacity: 0.8; color: #ffffff; } #rmp-search-box-16555 { display: block; padding-top: 0px; padding-left: 5%; padding-bottom: 0px; padding-right: 5%; } #rmp-search-box-16555 .rmp-search-form { margin: 0; } #rmp-search-box-16555 .rmp-search-box { background: #ffffff; border: 1px solid #dadada; color: #333333; width: 100%; padding: 0 5%; border-radius: 30px; height: 45px; -webkit-appearance: none; } #rmp-search-box-16555 .rmp-search-box::placeholder { color: #c7c7cd; } #rmp-search-box-16555 .rmp-search-box:focus { background-color: #ffffff; outline: 2px solid #dadada; color: #333333; } #rmp-menu-title-16555 { background-color: #3f3f3f; color: #ffffff; text-align: left; font-size: 13px; padding-top: 10%; padding-left: 5%; padding-bottom: 0%; padding-right: 5%; font-weight: 400; transition: background-color 0.5s, border-color 0.5s, color 0.5s; } #rmp-menu-title-16555:hover { background-color: #3f3f3f; color: #ffffff; } #rmp-menu-title-16555 > .rmp-menu-title-link { color: #ffffff; width: 100%; background-color: unset; text-decoration: none; } #rmp-menu-title-16555 > .rmp-menu-title-link:hover { color: #ffffff; } #rmp-menu-title-16555 .rmp-font-icon { font-size: 13px; } #rmp-menu-additional-content-16555 { padding-top: 0px; padding-left: 5%; padding-bottom: 0px; padding-right: 5%; color: #ffffff; text-align: center; font-size: 16px; } } /** This file contents common styling of menus. */ .rmp-container { display: none; visibility: visible; padding: 0px 0px 0px 0px; z-index: 99998; transition: all 0.3s; /** Scrolling bar in menu setting box **/ } .rmp-container.rmp-fade-top, .rmp-container.rmp-fade-left, .rmp-container.rmp-fade-right, .rmp-container.rmp-fade-bottom { display: none; } .rmp-container.rmp-slide-left, .rmp-container.rmp-push-left { transform: translateX(-100%); -ms-transform: translateX(-100%); -webkit-transform: translateX(-100%); -moz-transform: translateX(-100%); } .rmp-container.rmp-slide-left.rmp-menu-open, .rmp-container.rmp-push-left.rmp-menu-open { transform: translateX(0); -ms-transform: translateX(0); -webkit-transform: translateX(0); -moz-transform: translateX(0); } .rmp-container.rmp-slide-right, .rmp-container.rmp-push-right { transform: translateX(100%); -ms-transform: translateX(100%); -webkit-transform: translateX(100%); -moz-transform: translateX(100%); } .rmp-container.rmp-slide-right.rmp-menu-open, .rmp-container.rmp-push-right.rmp-menu-open { transform: translateX(0); -ms-transform: translateX(0); -webkit-transform: translateX(0); -moz-transform: translateX(0); } .rmp-container.rmp-slide-top, .rmp-container.rmp-push-top { transform: translateY(-100%); -ms-transform: translateY(-100%); -webkit-transform: translateY(-100%); -moz-transform: translateY(-100%); } .rmp-container.rmp-slide-top.rmp-menu-open, .rmp-container.rmp-push-top.rmp-menu-open { transform: translateY(0); -ms-transform: translateY(0); -webkit-transform: translateY(0); -moz-transform: translateY(0); } .rmp-container.rmp-slide-bottom, .rmp-container.rmp-push-bottom { transform: translateY(100%); -ms-transform: translateY(100%); -webkit-transform: translateY(100%); -moz-transform: translateY(100%); } .rmp-container.rmp-slide-bottom.rmp-menu-open, .rmp-container.rmp-push-bottom.rmp-menu-open { transform: translateX(0); -ms-transform: translateX(0); -webkit-transform: translateX(0); -moz-transform: translateX(0); } .rmp-container::-webkit-scrollbar { width: 0px; } .rmp-container ::-webkit-scrollbar-track { box-shadow: inset 0 0 5px transparent; } .rmp-container ::-webkit-scrollbar-thumb { background: transparent; } .rmp-container ::-webkit-scrollbar-thumb:hover { background: transparent; } .rmp-container .rmp-menu-wrap .rmp-menu { transition: none; border-radius: 0; box-shadow: none; background: none; border: 0; bottom: auto; box-sizing: border-box; clip: auto; color: #666; display: block; float: none; font-family: inherit; font-size: 14px; height: auto; left: auto; line-height: 1.7; list-style-type: none; margin: 0; min-height: auto; max-height: none; opacity: 1; outline: none; overflow: visible; padding: 0; position: relative; pointer-events: auto; right: auto; text-align: left; text-decoration: none; text-indent: 0; text-transform: none; transform: none; top: auto; visibility: inherit; width: auto; word-wrap: break-word; white-space: normal; } .rmp-container .rmp-menu-additional-content { display: block; word-break: break-word; } .rmp-container .rmp-menu-title { display: flex; flex-direction: column; } .rmp-container .rmp-menu-title .rmp-menu-title-image { max-width: 100%; margin-bottom: 15px; display: block; margin: auto; margin-bottom: 15px; } button.rmp_menu_trigger { z-index: 999999; overflow: hidden; outline: none; border: 0; display: none; margin: 0; transition: transform 0.5s, background-color 0.5s; padding: 0; } button.rmp_menu_trigger .responsive-menu-pro-inner::before, button.rmp_menu_trigger .responsive-menu-pro-inner::after { content: ""; display: block; } button.rmp_menu_trigger .responsive-menu-pro-inner::before { top: 10px; } button.rmp_menu_trigger .responsive-menu-pro-inner::after { bottom: 10px; } button.rmp_menu_trigger .rmp-trigger-box { width: 40px; display: inline-block; position: relative; pointer-events: none; vertical-align: super; } /* Menu Trigger Boring Animation */ .rmp-menu-trigger-boring .responsive-menu-pro-inner { transition-property: none; } .rmp-menu-trigger-boring .responsive-menu-pro-inner::after, .rmp-menu-trigger-boring .responsive-menu-pro-inner::before { transition-property: none; } .rmp-menu-trigger-boring.is-active .responsive-menu-pro-inner { transform: rotate(45deg); } .rmp-menu-trigger-boring.is-active .responsive-menu-pro-inner:before { top: 0; opacity: 0; } .rmp-menu-trigger-boring.is-active .responsive-menu-pro-inner:after { bottom: 0; transform: rotate(-90deg); } </style> <link rel='stylesheet' id='dashicons-css' href='https://www.emilysentourage.org/wp-includes/css/dashicons.min.css?ver=6.7.1' type='text/css' media='all' /> <link rel='stylesheet' id='woocommerce-layout-css' href='https://www.emilysentourage.org/wp-content/plugins/woocommerce/assets/css/woocommerce-layout.css?ver=9.4.2' type='text/css' media='all' /> <style id='woocommerce-layout-inline-css' type='text/css'> .infinite-scroll .woocommerce-pagination { 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offset - distance : offset; jQuery('html, body').animate({ scrollTop : offsetTop}, 500); }; Bloomerang.Api.OnError = Bloomerang.Widget.Email.OnError = function (response) { jQuery(".btn-submit-email").val("Register").prop("disabled", false).removeClass("disabled"); jQuery("#email-registration-form-container .errors").removeClass("hidden").html(response.Message); var distance = 100; var offset = jQuery("#email-registration-form-container .errors").offset().top; var offsetTop = offset > distance ? offset - distance : offset; jQuery('html, body').animate({ scrollTop : offsetTop}, 500); if (typeof(grecaptcha) !== "undefined" && jQuery("#captcha" + Bloomerang.Data.WidgetIds.EmailSignup).children().length) { grecaptcha.reset(jQuery(".email-registration-form").data("captcha-id")); } }; Bloomerang.Util.applyEmailSignupCustomFields = function (obj, type) { // Clear any fields from a previous failed submission obj.clearCustomFields(); // Apply all <input> (not multiselect), <select> and <textarea> fields jQuery(".email-registration-form .section.custom-fields :input:not(a > input, select)[id*=" + type + "]").each(function() { if (jQuery(this).val().hasValue()) { obj.customFreeformField(jQuery(this).attr("id").toUntypedValue(), jQuery(this).val()); } }); // Apply all <select> fields jQuery(".email-registration-form .section.custom-fields select[id*=" + type + "]").each(function() { if (jQuery(this).val().hasValue()) { obj.customPickField(jQuery(this).attr("id").toUntypedValue(), jQuery(this).val()); } }); // Apply all multiselect fields jQuery(".email-registration-form .section.custom-fields .checkboxes[id*=" + type + "]").each(function() { obj.customPickField(jQuery(this).attr("id").toUntypedValue(), jQuery.map(jQuery(this).children(".checkbox.selected"), function(v) { return jQuery(v).attr("data-id"); })); }); }; String.prototype.hasValue = function() { return (this && jQuery.trim(this)); //IE8 doesn't have a native trim function }; Bloomerang.Account.applyEmailSignupCustomFields = function () { Bloomerang.Util.applyEmailSignupCustomFields(this, "Account"); return this; }; Bloomerang.Interaction.applyEmailSignupCustomFields = function () { Bloomerang.Util.applyEmailSignupCustomFields(this, "Interaction"); return this; }; String.prototype.toUntypedValue = function() { return this.substring(this.indexOf('_') + 1); }; jQuery.validator.addMethod("currency", function (value, element, options) { return !value || value .replace("$", "") .replace(".", "") .split(",").join("") .match(/^\d+$/g); }, "Not a valid currency"); jQuery.validator.classRuleSettings.currency = { currency: true }; jQuery.validator.addMethod("number", function (value, element, options) { return !value || value .replace(".", "") .split(",").join("") .match(/^\d+$/g); }, "Not a valid number"); jQuery.validator.classRuleSettings.number = { number: true }; jQuery.validator.addMethod("validYear", function (value, element, options) { try { return (!value || value.match(/^[1-9]\d\d\d$/)) ? true : false; } catch (e) { return false; } }, function () { return "Must be a 4 digit year"; }); jQuery.validator.classRuleSettings.validYear = { validYear: true }; // Intercept form submission to validate then submit via API jQuery("#email-registration-form-container form").validate({ submitHandler: function () { if (!Bloomerang.ValidateEmailSignupFormCaptcha()) { return false; } // Restore proper callbacks in case there are multiple widgets on the page Bloomerang.Api.OnSubmit = Bloomerang.Widget.Email.OnSubmit; Bloomerang.Api.OnSuccess = Bloomerang.Widget.Email.OnSuccess; Bloomerang.Api.OnError = Bloomerang.Widget.Email.OnError; Bloomerang.Api.joinMailingList(); } }); })(jQuery); }; var startBloomerangLoad = function() { if (window.bloomerangLoadStarted == undefined) { window.bloomerangLoadStarted = true; var script = document.createElement('script'); script.type = 'text/javascript'; script.src = 'https://crm.bloomerang.co/Content/Scripts/Api/Bloomerang-v2.js?nocache=2018-05-30'; document.getElementsByTagName('head')[0].appendChild(script); waitForBloomerangLoad(function() { Bloomerang.Util.requireJQueryValidation(function() { insertForm9833472(); })}); } else { waitForBloomerangLoad(function() { Bloomerang.Util.requireJQueryValidation(function() { insertForm9833472(); })}); } }; var waitForBloomerangLoad = function(callback) { if (typeof(Bloomerang) === 'undefined' || !Bloomerang._isReady) { setTimeout(function () { waitForBloomerangLoad(callback) }, 500); } else { if (true) { callback(); } else { window.bloomerangLoadStarted = undefined; Bloomerang = undefined; // The version of Blomerang.js is not what we want. So blow it away and reload. startBloomerangLoad(); } } }; startBloomerangLoad(); </script> <span class="ee-popup-close"><i class="fa fa-times"></i></span> </div> </div> <!-- Single Page Popup --> <div class="body-wrapper donate_page_wrapper_cls" data-home="https://www.emilysentourage.org" > <header class="gdlr-header-wrapper gdlr-header-style-2 gdlr-centered"> <!-- top navigation --> <!-- custom header code --> <!-- logo --> <div class="gdlr-header-substitute"> <div class="gdlr-header-container container"> <div class="gdlr-header-inner"> <!-- logo --> <div class="gdlr-logo gdlr-align-left"> <a href="https://www.emilysentourage.org" > <img src="https://www.emilysentourage.org/wp-content/uploads/2014/10/EE_Logo1.png" alt="" width="240" height="150" /> </a> <div class="gdlr-responsive-navigation dl-menuwrapper" id="gdlr-responsive-navigation" ><button class="dl-trigger">Open Menu</button><ul id="menu-main-menu" class="dl-menu gdlr-main-mobile-menu"><li id="menu-item-13988" 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class="clear"></div></div><div class="clear"></div></nav></div></div></div> <div class="gdlr-page-title-wrapper" > <div class="gdlr-page-title-container container" > <div class="gdlr-page-title-inner" > <h3 class="gdlr-page-title"></h3> </div> </div> </div> <!-- is search --> </header> <div class="content-wrapper dasdas"> <div class="gdlr-content"> <div class="with-sidebar-wrapper"> <div class="with-sidebar-container container"> <div class="with-sidebar-left twelve columns"> <div class="with-sidebar-content twelve columns"> <div class="gdlr-item gdlr-blog-full gdlr-item-start-content"> <!-- get the content based on post format --> <article id="post-16817" class="post-16817 post type-post status-publish format-standard has-post-thumbnail hentry category-uncategorized"> <div class="gdlr-standard-style"> <div class="gdlr-blog-thumbnail"> </div> <div class="blog-content-wrapper" > <header class="post-header"> <div class="gdlr-blog-info gdlr-info"><div class="blog-info blog-date"><i class="icon-time fa fa-clock-o"></i><a href="https://www.emilysentourage.org/2022/05/20/">20 May 2022</a></div><div class="clear"></div></div> <h1 class="gdlr-blog-title">My Experience with Phage Therapy: 3 Years Later</h1> <div class="clear"></div> </header><!-- entry-header --> <div class="gdlr-blog-content"><p><i><span style="font-weight: 400;">During CF Awareness Month, Emily’s Entourage (EE) invites members of the cystic fibrosis (CF) community to share their stories. Today’s blog post is by Ella Balasa, a patient advocate and consultant who lives with CF. </span></i></p> <p><span style="font-weight: 400;">In 2019 at the age of 26, I underwent an experimental therapy to fight the worst CF infection I’d ever had. It worked. Three years later, I am here because of that one-in-a-million shot.</span></p> <h2><b>A Desperate Experiment </b></h2> <p><span style="font-weight: 400;">The untested experimental treatment that, at the time, neither I nor my doctor had heard of is called “phage therapy.” Bacteriophages, also known as phages, are viruses that attack a specific bacterial host and not other cells. Find the right phage, we learned, and you can use it to treat a particular bacteria. </span></p> <p><span style="font-weight: 400;">Reaching that point of desperation was not surprising. Diagnosed with CF at age 1, I was constantly on antibiotics for various infections. I knew that one day, the antibiotic therapies that helped me my entire life might suddenly become ineffective due to antibiotic resistance. </span></p> <p><span style="font-weight: 400;">That day came when I was 26 years old and experienced the worst infection I’d ever had. I was on intravenous antibiotics for weeks and I wasn’t having any relief of my symptoms. I was coughing nonstop and large green mucus plugs were constantly being expelled. I was doing breathing treatments every two hours or so just to quiet the wheezing and secretions in my airways as I breathed. My lung function dropped to 18% and I was put on supplementary oxygen. My feelings of fear and desperation shot through the ceiling.</span></p> <p><span style="font-weight: 400;">A few months earlier, I had been in touch with some filmmakers who were shooting a documentary on CF. They had told me abo</span>ut a CF patient being treated in Texas with an experimental treatment called “phage therapy” to combat an infection that was resistant to available antibiotics. In my haze I wondered, could this be a viable treatment for me?</p> <p><span style="font-weight: 400;">Given the severity of my infection, the advanced stage of my CF, and the dearth of options for me at that point, I felt I had nothing to lose. I brought the notion of phage therapy to my doctor and we contacted researchers at Yale University. A few weeks later, I found myself at Yale, sitting on a gurney, inhaling phages developed just for me. </span></p> <h2><b>Risk and Reward</b></h2> <p><span style="font-weight: 400;">After a one-week course of treatment, I began to clear the infection. This was truly nothing short of a miracle. So many treatments had failed or delivered mediocre results. My body’s response was shocking and exhilarating. I had used the phage treatment along with a cocktail of antibiotics that I had used many times, so I knew the addition of phage was the x-factor that made the difference.</span></p> <p><img fetchpriority="high" decoding="async" class="alignnone wp-image-16825" src="https://www.emilysentourage.org/wp-content/uploads/First-treatment-of-phage-therapy-300x200.jpeg" alt="" width="1085" height="724" srcset="https://www.emilysentourage.org/wp-content/uploads/First-treatment-of-phage-therapy-300x200.jpeg 300w, https://www.emilysentourage.org/wp-content/uploads/First-treatment-of-phage-therapy-768x512.jpeg 768w, https://www.emilysentourage.org/wp-content/uploads/First-treatment-of-phage-therapy-18x12.jpeg 18w, https://www.emilysentourage.org/wp-content/uploads/First-treatment-of-phage-therapy-600x400.jpeg 600w, https://www.emilysentourage.org/wp-content/uploads/First-treatment-of-phage-therapy.jpeg 970w" sizes="(max-width: 1085px) 100vw, 1085px" /></p> <p><span style="font-weight: 400;">Three months later, I received another round of phage treatment. After that treatment, I remained infection-free for six months. This was an incredible boost to my quality of life — up until this point, I had been on nearly constant antibiotics.</span></p> <p><span style="font-weight: 400;">When these effects became less pronounced, I accessed phage for a third time. In the intervening time between treatments, I had taken multiple courses of oral and inhaled antibiotics. The antibiotic use had altered my bacterial population and the likelihood of finding the phage which would respond to the specific conditions in my body at that moment were low. Think about it like there are many switches and levers the bacteria can turn on and off. When some of those are engaged, they can fend off even phage that might work against them in another situation. Even within one individual, the treatment for a particular strain in one area of the body may not even translate to broader efficacy. </span></p> <p><span style="font-weight: 400;">This time, the odds went against me: The course of phage therapy was not effective and I saw no changes. Now, my team of health professionals have to go back to the drawing board, analyzing my specific bacteria and identifying the right phage to treat it. </span></p> <p><span style="font-weight: 400;">Am I disappointed that phage didn’t work for me this time? Yes, absolutely. That does not mean that it no longer has promise, just like my previous success with phage didn’t constitute a miracle cure. </span></p> <p><span style="font-weight: 400;">Solutions for vexing issues like antibiotic resistance are rarely silver bullets. Rather, the goal is to spur innovation and research and try multiple approaches. </span></p> <blockquote><p><span style="font-weight: 400;">Given my experience and the experiences of many others with CF and other antibiotic-resistant infections that have benefited from phage therapy when all else has failed, it seems clear that phage therapy carries promise, but it is just one approach. We need to be firing on all fronts. </span></p></blockquote> <h2><b>Future of Phage</b></h2> <p><span style="font-weight: 400;">There’s a good chance I wouldn’t be here today without phage therapy. As a long term solution, there are challenges that are hard to contend with.</span><span style="font-weight: 400;"> </span></p> <p><span style="font-weight: 400;">With a treatment that must be developed and </span><span style="font-weight: 400;">deployed on a case-by-case basis, it’s hard to extrapolate how one person’s experience might translate to a larger population. </span><span style="font-weight: 400;">Because there is so much biodiversity in phages, there is likely a phage which can respond to each unique circumstance. Identifying that precise phage which suits the right person in the right circumstances is the looming hurdle that makes success such a gamble.</span></p> <p><span style="font-weight: 400;">Other challenges of phage therapy include the short shelf-life of phage and the uncertain commercial environment for anti-infectives companies today. There are early clinical trials underway for </span><i><span style="font-weight: 400;">pseudomonas aeruginosa</span></i><span style="font-weight: 400;">, the most common bacterial infection in people with CF. </span><span style="font-weight: 400;">The data that results from these trials will be critical to build a stronger case for </span><span style="font-weight: 400;">phage as </span>a treatment option.</p> <h2><img decoding="async" class="alignnone wp-image-16824" style="font-size: 16px;" src="https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--1096x482.jpg" alt="" width="1086" height="896" srcset="https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--300x247.jpg 300w, https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--1024x845.jpg 1024w, https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--768x634.jpg 768w, https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--1536x1267.jpg 1536w, https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--2048x1689.jpg 2048w, https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--15x12.jpg 15w, https://www.emilysentourage.org/wp-content/uploads/Breath-Wall-Durham--600x495.jpg 600w" sizes="(max-width: 1086px) 100vw, 1086px" /><b>What’s Next</b></h2> <p><span style="font-weight: 400;">Phage represents just one possibility for infection management among many nascent and yet-undiscovered ones. The truth is, I was very sick each time I underwent phage therapy, and I still am. My lung function is still dangerously low. In 2019 I started on a modulator which helped me significantly, but after two years the effects of this treatment have become less pronounced. I am in the position where I must find an effective treatment once again.</span></p> <p><span style="font-weight: 400;">Progress in science happens in stops and starts. In my case, the serendipity of timing presented me an option – as risky and untested as it was – where no other options existed, and for that, I’m very grateful. Propelling forward quickly and exploring out-of-the-box options like phage is the only way to develop better solutions for people like me whose lives depend on it and who do not have time to wait.</span></p> <p> </p> <p><em>Special thanks to Vertex Pharmaceuticals, Inc. for their tier 1 sponsorship of our CF Awareness Month campaign.</em></p> </div> <div class="gdlr-single-blog-tag"> </div> </div> <!-- blog content wrapper --> </div> </article><!-- #post --> <div class="gdlr-social-share"> <span class="social-share-title">Share Post:</span> <a href="http://www.facebook.com/share.php?u=https://www.emilysentourage.org/my-experience-with-phage-therapy-3-years-later/" target="_blank"> <img src="https://www.emilysentourage.org/wp-content/themes/charityhub/images/dark/social-icon/facebook.png" alt="facebook-share" width="32" height="32" /> </a> <a href="http://www.linkedin.com/shareArticle?mini=true&url=https://www.emilysentourage.org/my-experience-with-phage-therapy-3-years-later/&title=My%20Experience%20with%20Phage%20Therapy%3A%203%20Years%20Later" target="_blank"> <img src="https://www.emilysentourage.org/wp-content/themes/charityhub/images/dark/social-icon/linkedin.png" alt="linked-share" width="32" height="32" /> </a> <a href="http://twitter.com/intent/tweet?text=My%20Experience%20with%20Phage%20Therapy%3A%203%20Years%20Later - https://www.emilysentourage.org/my-experience-with-phage-therapy-3-years-later/" target="_blank"> <img src="https://www.emilysentourage.org/wp-content/themes/charityhub/images/dark/social-icon/twitter.png" alt="twitter-share" width="32" height="32"> </a> <div class="clear"></div> </div> <nav class="gdlr-single-nav"> <div class="previous-nav"><a href="https://www.emilysentourage.org/a-life-without-worry/" rel="prev"><i class="icon-angle-left"></i><span>A Life Without Worry</span></a></div> <div class="next-nav"><a href="https://www.emilysentourage.org/battling-two-deadly-diseases-my-crusade-to-lower-the-colon-cancer-screening-age/" rel="next"><span>Battling Two Deadly Diseases: My Crusade to Lower the Colon Cancer Screening Age</span><i class="icon-angle-right"></i></a></div> <div class="clear"></div> </nav><!-- .nav-single --> <!-- abou author section --> <em>The opinions stated by our guest contributors reflect the experiences and thoughts of the author alone. 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true); jQuery('.generaldonation-subs-eeform #state, .bloomerang_donateproductsdonate #state').on('change', function (e) { var optionSelected = jQuery("option:selected", this); var valueSelected = this.value; jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #Pennsylvania_id').removeClass('selected'); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #Pennsylvania_id input').prop('checked', false); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #new_york_id').removeClass('selected'); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #new_york_id input').prop('checked', false); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields .checkbox.ee_selected_field_formfield').addClass('selected'); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields .checkbox.ee_selected_field_formfield input').prop('checked', true); if(valueSelected == 'NY'){ jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #new_york_id').addClass('selected'); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #new_york_id input').prop('checked', true); } else if(valueSelected == 'PA'){ jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #Pennsylvania_id').addClass('selected'); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #Pennsylvania_id input').prop('checked', true); } else if(valueSelected == 'CT'){ jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #new_york_id').addClass('selected'); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #new_york_id input').prop('checked', true); } else if(valueSelected == 'DE'){ jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #Pennsylvania_id').addClass('selected'); jQuery('.generaldonation-subs-eeform, .bloomerang_donateproductsdonate').find('.custom-fields #Pennsylvania_id input').prop('checked', true); } }); }, 5000); /* Assign list as per donation amount. */ jQuery(document).on("blur", "#other-amount", function(e){ var donation_amount = jQuery('[name="donation-level"]:checked').val(); ee_assign_list_as_per_donation(donation_amount); }); jQuery(document).on("click", '[name="donation-level"]', function(e){ var donation_amount = jQuery(this).val(); ee_assign_list_as_per_donation(donation_amount); }); /* function to assign list. */ function ee_assign_list_as_per_donation(donation_amount) { /* if donation is greater than 2000 dollor. */ if(donation_amount && parseFloat(donation_amount) > 2000) { jQuery('.vip_newsletter_list').addClass('selected'); jQuery('.vip_newsletter_list').find('input').prop('checked', true); } else { jQuery('.vip_newsletter_list').removeClass('selected'); jQuery('.vip_newsletter_list').find('input').prop('checked', false); } } //preventing users to submit the sorm if they have not selected atleast one reson for the connection to CF jQuery("#submit_interaction").prop("disabled", true); jQuery(".connection_to_cyctic").on("change", function(){ if (jQuery('.connection_to_cyctic.selected').length != 0) { jQuery("#submit_interaction").prop("disabled", false); jQuery("#cyctc_msg").text(""); }else{ jQuery("#submit_interaction").prop("disabled", true); jQuery("#cyctc_msg").text("Please select at least one Connection to Cystic Fibrosis"); } }); }); })(jQuery); </script> <template id="tp-language" data-tp-language="en_US"></template> <button type="button" aria-controls="rmp-container-16555" aria-label="Menu Trigger" id="rmp_menu_trigger-16555" 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