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$(".js-view-count[data-work-id=13859982]").text(description); $(".js-view-count-work_13859982").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_13859982").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="13859982"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="71300" href="https://www.academia.edu/Documents/in/Blood_Glucose">Blood Glucose</a>, <script data-card-contents-for-ri="71300" type="text/json">{"id":71300,"name":"Blood Glucose","url":"https://www.academia.edu/Documents/in/Blood_Glucose?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="71459" href="https://www.academia.edu/Documents/in/Fasting">Fasting</a>, <script data-card-contents-for-ri="71459" type="text/json">{"id":71459,"name":"Fasting","url":"https://www.academia.edu/Documents/in/Fasting?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="289271" href="https://www.academia.edu/Documents/in/Aged">Aged</a>, <script data-card-contents-for-ri="289271" type="text/json">{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="789977" href="https://www.academia.edu/Documents/in/Coronary_Artery_Disease">Coronary Artery Disease</a><script data-card-contents-for-ri="789977" type="text/json">{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=13859982]'), work: {"id":13859982,"title":"Choosing the right TKI for chronic myeloid leukemia: When the truth lies in “long-term” safety and efficacy","created_at":"2015-07-09T22:44:36.429-07:00","url":"https://www.academia.edu/13859982/Choosing_the_right_TKI_for_chronic_myeloid_leukemia_When_the_truth_lies_in_long_term_safety_and_efficacy?f_ri=1819400","dom_id":"work_13859982","summary":null,"downloadable_attachments":[{"id":44870043,"asset_id":13859982,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32950615,"first_name":"Rocco","last_name":"Piazza","domain_name":"independent","page_name":"RoccoPiazza","display_name":"Rocco Piazza","profile_url":"https://independent.academia.edu/RoccoPiazza?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":71300,"name":"Blood Glucose","url":"https://www.academia.edu/Documents/in/Blood_Glucose?f_ri=1819400","nofollow":false},{"id":71459,"name":"Fasting","url":"https://www.academia.edu/Documents/in/Fasting?f_ri=1819400","nofollow":false},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=1819400","nofollow":false},{"id":789977,"name":"Coronary Artery Disease","url":"https://www.academia.edu/Documents/in/Coronary_Artery_Disease?f_ri=1819400","nofollow":false},{"id":1148860,"name":"Peripheral Arterial Disease","url":"https://www.academia.edu/Documents/in/Peripheral_Arterial_Disease?f_ri=1819400"},{"id":1343089,"name":"Protein Kinase Inhibitors","url":"https://www.academia.edu/Documents/in/Protein_Kinase_Inhibitors?f_ri=1819400"},{"id":1524090,"name":"Benzamides","url":"https://www.academia.edu/Documents/in/Benzamides?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_5491847" data-work_id="5491847" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/5491847/Clinical_and_molecular_features_of_mitochondrial_DNA_depletion_syndromes">Clinical and molecular features of mitochondrial DNA depletion syndromes</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Mitochondrial DNA depletion syndromes (MDSs) form a group of autosomal recessive disorders characterized by profoundly decreased mitochondrial DNA copy numbers in affected tissues. Three main clinical presentations are known: myopathic,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_5491847" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Mitochondrial DNA depletion syndromes (MDSs) form a group of autosomal recessive disorders characterized by profoundly decreased mitochondrial DNA copy numbers in affected tissues. Three main clinical presentations are known: myopathic, encephalomyopathic and hepatocerebral. The first is associated with mutations in thymidine kinase 2 (TK2) and p53-induced ribonucleotide reductase B subunit (RRM2B); the second with mutations in succinate synthase A (SUCLA2) and B (SUCLG1); the third with mutations in Twinkle (PEO1), pol-γA (POLG1), deoxyguanosine kinase (DGUOK) and MPV17 (MPV17). In this work, we review the MDS-associated phenotypes and present our own experience of 32 MDS patients, with the aim of defining the mutation frequency of the known genes, the clinical spectrum of the diseases, and the genotype–phenotype correlations. Five of our patients carried previously unreported mutations in one of the eight MDS genes.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/5491847" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0e3bc872769ac5ecd91bc41df36a2eed" rel="nofollow" data-download="{"attachment_id":49272469,"asset_id":5491847,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/49272469/download_file?st=MTczMjc1ODMxMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="7734703" href="https://mrc.academia.edu/antonellaSpinazzola">antonella Spinazzola</a><script data-card-contents-for-user="7734703" type="text/json">{"id":7734703,"first_name":"antonella","last_name":"Spinazzola","domain_name":"mrc","page_name":"antonellaSpinazzola","display_name":"antonella Spinazzola","profile_url":"https://mrc.academia.edu/antonellaSpinazzola?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_5491847 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="5491847"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 5491847, container: ".js-paper-rank-work_5491847", }); 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$(".js-view-count[data-work-id=5491847]").text(description); $(".js-view-count-work_5491847").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_5491847").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="5491847"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">21</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4228" href="https://www.academia.edu/Documents/in/Skeletal_muscle_biology">Skeletal muscle biology</a>, <script data-card-contents-for-ri="4228" type="text/json">{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="10904" href="https://www.academia.edu/Documents/in/Electroencephalography">Electroencephalography</a>, <script data-card-contents-for-ri="10904" type="text/json">{"id":10904,"name":"Electroencephalography","url":"https://www.academia.edu/Documents/in/Electroencephalography?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="61474" href="https://www.academia.edu/Documents/in/Brain">Brain</a><script data-card-contents-for-ri="61474" type="text/json">{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=5491847]'), work: {"id":5491847,"title":"Clinical and molecular features of mitochondrial DNA depletion syndromes","created_at":"2013-12-20T18:03:33.454-08:00","url":"https://www.academia.edu/5491847/Clinical_and_molecular_features_of_mitochondrial_DNA_depletion_syndromes?f_ri=1819400","dom_id":"work_5491847","summary":"Mitochondrial DNA depletion syndromes (MDSs) form a group of autosomal recessive disorders characterized by profoundly decreased mitochondrial DNA copy numbers in affected tissues. Three main clinical presentations are known: myopathic, encephalomyopathic and hepatocerebral. The first is associated with mutations in thymidine kinase 2 (TK2) and p53-induced ribonucleotide reductase B subunit (RRM2B); the second with mutations in succinate synthase A (SUCLA2) and B (SUCLG1); the third with mutations in Twinkle (PEO1), pol-γA (POLG1), deoxyguanosine kinase (DGUOK) and MPV17 (MPV17). In this work, we review the MDS-associated phenotypes and present our own experience of 32 MDS patients, with the aim of defining the mutation frequency of the known genes, the clinical spectrum of the diseases, and the genotype–phenotype correlations. Five of our patients carried previously unreported mutations in one of the eight MDS genes.","downloadable_attachments":[{"id":49272469,"asset_id":5491847,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":7734703,"first_name":"antonella","last_name":"Spinazzola","domain_name":"mrc","page_name":"antonellaSpinazzola","display_name":"antonella Spinazzola","profile_url":"https://mrc.academia.edu/antonellaSpinazzola?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":4228,"name":"Skeletal muscle biology","url":"https://www.academia.edu/Documents/in/Skeletal_muscle_biology?f_ri=1819400","nofollow":false},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=1819400","nofollow":false},{"id":10904,"name":"Electroencephalography","url":"https://www.academia.edu/Documents/in/Electroencephalography?f_ri=1819400","nofollow":false},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=1819400","nofollow":false},{"id":63093,"name":"Mitochondrial DNA","url":"https://www.academia.edu/Documents/in/Mitochondrial_DNA?f_ri=1819400"},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=1819400"},{"id":71437,"name":"Liver","url":"https://www.academia.edu/Documents/in/Liver?f_ri=1819400"},{"id":74780,"name":"Mutation","url":"https://www.academia.edu/Documents/in/Mutation?f_ri=1819400"},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=1819400"},{"id":170918,"name":"Electromyography","url":"https://www.academia.edu/Documents/in/Electromyography?f_ri=1819400"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=1819400"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=1819400"},{"id":290205,"name":"Mitochondrial Diseases","url":"https://www.academia.edu/Documents/in/Mitochondrial_Diseases?f_ri=1819400"},{"id":321836,"name":"Spectrum","url":"https://www.academia.edu/Documents/in/Spectrum?f_ri=1819400"},{"id":627622,"name":"Thymidine Kinase","url":"https://www.academia.edu/Documents/in/Thymidine_Kinase?f_ri=1819400"},{"id":830071,"name":"Ribonucleotide Reductase","url":"https://www.academia.edu/Documents/in/Ribonucleotide_Reductase?f_ri=1819400"},{"id":961812,"name":"Autosomal Recessive","url":"https://www.academia.edu/Documents/in/Autosomal_Recessive?f_ri=1819400"},{"id":985062,"name":"Clinical Presentation","url":"https://www.academia.edu/Documents/in/Clinical_Presentation?f_ri=1819400"},{"id":1489115,"name":"Age of Onset","url":"https://www.academia.edu/Documents/in/Age_of_Onset?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48188270" data-work_id="48188270" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48188270/Endoscopic_options_in_children_experience_with_134_procedures">Endoscopic options in children: experience with 134 procedures</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">There are frequent applications for endoscopy in neurosurgery. However, endoscopic surgery in children has peculiar characteristics and is associated with different rates of success. In this study, the authors report on their experience... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48188270" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">There are frequent applications for endoscopy in neurosurgery. However, endoscopic surgery in children has peculiar characteristics and is associated with different rates of success. In this study, the authors report on their experience with 134 consecutive endoscopy procedures performed in 126 patients&lt;18 years of age. Between April 1993 and October 2007, 134 endoscopic procedures were performed in 126 children. Indications for surgery included brain tumors in 48 children, cystic lesions in 24, aqueductal stenosis in 23, various malformations in 20, hemorrhage and infarction in 6, and isolated ventricles in 5 children. In this long-term followup study, data were analyzed with respect to clinical and radiological success rates, as well as shunt dependence both in relation to lesion origin, and to the type of endoscopic procedure performed (endoscopic third ventriculostomy [ETV], septostomy, aqueductoplasty, or cystocisternostomy). Finally, the influence of patient age on the succ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48188270" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="276342eafbdc3e2ce3a8210715951e62" rel="nofollow" data-download="{"attachment_id":66930764,"asset_id":48188270,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/66930764/download_file?st=MTczMjc1ODMxMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="135463868" href="https://independent.academia.edu/JoachimOertel">Joachim Oertel</a><script data-card-contents-for-user="135463868" type="text/json">{"id":135463868,"first_name":"Joachim","last_name":"Oertel","domain_name":"independent","page_name":"JoachimOertel","display_name":"Joachim Oertel","profile_url":"https://independent.academia.edu/JoachimOertel?f_ri=1819400","photo":"https://0.academia-photos.com/135463868/38819199/32342885/s65_joachim.oertel.jpg"}</script></span></span></li><li class="js-paper-rank-work_48188270 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48188270"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48188270, container: ".js-paper-rank-work_48188270", }); 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However, endoscopic surgery in children has peculiar characteristics and is associated with different rates of success. In this study, the authors report on their experience with 134 consecutive endoscopy procedures performed in 126 patients\u0026lt;18 years of age. Between April 1993 and October 2007, 134 endoscopic procedures were performed in 126 children. Indications for surgery included brain tumors in 48 children, cystic lesions in 24, aqueductal stenosis in 23, various malformations in 20, hemorrhage and infarction in 6, and isolated ventricles in 5 children. In this long-term followup study, data were analyzed with respect to clinical and radiological success rates, as well as shunt dependence both in relation to lesion origin, and to the type of endoscopic procedure performed (endoscopic third ventriculostomy [ETV], septostomy, aqueductoplasty, or cystocisternostomy). Finally, the influence of patient age on the succ...","downloadable_attachments":[{"id":66930764,"asset_id":48188270,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":135463868,"first_name":"Joachim","last_name":"Oertel","domain_name":"independent","page_name":"JoachimOertel","display_name":"Joachim Oertel","profile_url":"https://independent.academia.edu/JoachimOertel?f_ri=1819400","photo":"https://0.academia-photos.com/135463868/38819199/32342885/s65_joachim.oertel.jpg"}],"research_interests":[{"id":650,"name":"Neurosurgery","url":"https://www.academia.edu/Documents/in/Neurosurgery?f_ri=1819400","nofollow":false},{"id":12426,"name":"Treatment 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identify LPI parameters influencing these phenomena. DESIGN: Cohort study derived from a randomized... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13297927" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">OBJECTIVE: To assess the impact of laser peripheral iridotomy (LPI) on forward-scatter of light and subjective visual symptoms and to identify LPI parameters influencing these phenomena. DESIGN: Cohort study derived from a randomized trial, using an external control group. PARTICIPANTS: Chinese subjects initially aged 50 or older and 70 years or younger with bilateral narrow angles undergoing LPI in 1 eye selected at random, and age- and gender-matched controls. METHODS: Eighteen months after laser, LPI-treated subjects underwent digital iris photography and photogrammetry to characterize the size and location of the LPI, Lens Opacity Classification System III cataract grading, and measurement of retinal straylight (C-Quant; OCULUS, Wetzlar, Germany) in the treated and untreated eyes and completed a visual symptoms questionnaire. Controls answered the questionnaire and underwent straylight measurement and (in a random one-sixth sample) cataract grading. 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})();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17965290" data-work_id="17965290" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17965290/Surgical_Management_of_Traumatic_Knee_Dislocation_With_Posterolateral_Corner_Injury">Surgical Management of Traumatic Knee Dislocation With Posterolateral Corner Injury</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">To evaluate the results of our method of surgical treatment of traumatic knee dislocation with injury to the posterolateral corner by use of a standardized protocol. Twenty-five consecutive patients presented with a grossly dislocated or... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_17965290" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To evaluate the results of our method of surgical treatment of traumatic knee dislocation with injury to the posterolateral corner by use of a standardized protocol. Twenty-five consecutive patients presented with a grossly dislocated or reduced knee. Five of these patients were not included in this series. The remaining 20 patients were treated by primary arthroscopic reconstruction. The anterior cruciate ligament (ACL) was reconstructed using gracilis tendon reinforced with artificial ligament (Ligament Augmentation and Reconstruction System [LARS] ligament); the posterior cruciate ligament (PCL) was reconstructed with semitendinosus tendon and reinforced with LARS ligament; and the posterolateral corner was treated using the gracilis and semitendinosus tendons from the uninjured knee. Twenty patients returned for subjective and objective evaluation at a minimum of 24 months after surgery. Early mobilization through continuous and active exercise was started on the fourth day postoperatively. At a mean follow-up of 44 months, the mean Lysholm score was 90 points, the mean score on the survey of daily activities was 90 points, and the sports activities score on the knee outcome survey averaged 80 points. By the rating of Meyers et al. the results were excellent in 6 patients, good in 10 patients, fair in 3 patients, and poor in one patient. The final International Knee Documentation Committee (IKDC) rating was not normal in any knee. The mean loss of extension was 2° (range, 0° to 3°) and loss of flexion was 12° (range, 10° to 15°). By using the described method of arthroscopically assisted reconstruction of the cruciate ligaments and the posterolateral corner, 80% of the patients had good subjective results and functional stability, and according to the IKDC scale, 45% of knees were nearly normal, 45% were abnormal, and 10% were severely abnormal. No patient&amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s rating returned to normal. Level IV, therapeutic case series.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17965290" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c28919860410f4ab89835b41f1a0b828" rel="nofollow" data-download="{"attachment_id":42213937,"asset_id":17965290,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42213937/download_file?st=MTczMjc1ODMxMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37395356" href="https://independent.academia.edu/samiribrahim2">samir ibrahim</a><script data-card-contents-for-user="37395356" type="text/json">{"id":37395356,"first_name":"samir","last_name":"ibrahim","domain_name":"independent","page_name":"samiribrahim2","display_name":"samir ibrahim","profile_url":"https://independent.academia.edu/samiribrahim2?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_17965290 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="17965290"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 17965290, container: ".js-paper-rank-work_17965290", }); 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Twenty-five consecutive patients presented with a grossly dislocated or reduced knee. Five of these patients were not included in this series. The remaining 20 patients were treated by primary arthroscopic reconstruction. The anterior cruciate ligament (ACL) was reconstructed using gracilis tendon reinforced with artificial ligament (Ligament Augmentation and Reconstruction System [LARS] ligament); the posterior cruciate ligament (PCL) was reconstructed with semitendinosus tendon and reinforced with LARS ligament; and the posterolateral corner was treated using the gracilis and semitendinosus tendons from the uninjured knee. Twenty patients returned for subjective and objective evaluation at a minimum of 24 months after surgery. Early mobilization through continuous and active exercise was started on the fourth day postoperatively. At a mean follow-up of 44 months, the mean Lysholm score was 90 points, the mean score on the survey of daily activities was 90 points, and the sports activities score on the knee outcome survey averaged 80 points. By the rating of Meyers et al. the results were excellent in 6 patients, good in 10 patients, fair in 3 patients, and poor in one patient. The final International Knee Documentation Committee (IKDC) rating was not normal in any knee. The mean loss of extension was 2° (range, 0° to 3°) and loss of flexion was 12° (range, 10° to 15°). By using the described method of arthroscopically assisted reconstruction of the cruciate ligaments and the posterolateral corner, 80% of the patients had good subjective results and functional stability, and according to the IKDC scale, 45% of knees were nearly normal, 45% were abnormal, and 10% were severely abnormal. No patient\u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;#39;s rating returned to normal. Level IV, therapeutic case series.","downloadable_attachments":[{"id":42213937,"asset_id":17965290,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37395356,"first_name":"samir","last_name":"ibrahim","domain_name":"independent","page_name":"samiribrahim2","display_name":"samir ibrahim","profile_url":"https://independent.academia.edu/samiribrahim2?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false},{"id":48627,"name":"Anterior Cruciate Ligament","url":"https://www.academia.edu/Documents/in/Anterior_Cruciate_Ligament?f_ri=1819400","nofollow":false},{"id":118122,"name":"Arthroscopy","url":"https://www.academia.edu/Documents/in/Arthroscopy?f_ri=1819400","nofollow":false},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=1819400","nofollow":false},{"id":244814,"name":"Clinical 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data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="76880" href="https://www.academia.edu/Documents/in/Hearing_disorders">Hearing disorders</a><script data-card-contents-for-ri="76880" type="text/json">{"id":76880,"name":"Hearing disorders","url":"https://www.academia.edu/Documents/in/Hearing_disorders?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=68552961]'), work: {"id":68552961,"title":"Auditory brainstem response in premature and full-term 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u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="648" href="https://www.academia.edu/Documents/in/Bariatric_Surgery">Bariatric Surgery</a>, <script data-card-contents-for-ri="648" type="text/json">{"id":648,"name":"Bariatric Surgery","url":"https://www.academia.edu/Documents/in/Bariatric_Surgery?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="41783" href="https://www.academia.edu/Documents/in/Ghrelin">Ghrelin</a>, <script data-card-contents-for-ri="41783" type="text/json">{"id":41783,"name":"Ghrelin","url":"https://www.academia.edu/Documents/in/Ghrelin?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="71300" href="https://www.academia.edu/Documents/in/Blood_Glucose">Blood Glucose</a>, <script data-card-contents-for-ri="71300" type="text/json">{"id":71300,"name":"Blood 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itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/61610560/High_nuclear_MSK1_is_associated_with_longer_survival_in_breast_cancer_patients">High nuclear MSK1 is associated with longer survival in breast cancer patients</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Mitogen- and stress-activated kinases (MSKs) are important substrates of the mitogen-activated protein kinase (MAPK)-activated protein kinase family. MSK1 and MSK2 are both nuclear serine/threonine protein kinases, with MSK1 being... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_61610560" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Mitogen- and stress-activated kinases (MSKs) are important substrates of the mitogen-activated protein kinase (MAPK)-activated protein kinase family. MSK1 and MSK2 are both nuclear serine/threonine protein kinases, with MSK1 being suggested to potentially play a role in breast cancer cell proliferation, cell cycle progression, cell migration, invasion and tumour growth. The aim of the current study was to assess MSK1 protein expression in breast cancer tumour specimens, evaluating its prognostic significance. A large cohort of 1902 early stage invasive breast cancer patients was used to explore the expression of MSK1. Protein expression was examined using standard immunohistochemistry on tissue microarrays. Low MSK1 protein expression was associated with younger age (P = 0.004), higher tumour grade (P &lt; 0.001), higher Nottingham Prognostic Index scores (P = 0.007), negative ER (P &lt; 0.001) and PR (P &lt; 0.001) status, and with triple-negative (P &lt; 0.001) and basal-like (P &...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/61610560" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="aa76622355c9b0ad4514ba7329173d23" rel="nofollow" data-download="{"attachment_id":74590379,"asset_id":61610560,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/74590379/download_file?st=MTczMjc1ODMxMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="58750969" href="https://independent.academia.edu/StewartMartin6">Stewart Martin</a><script data-card-contents-for-user="58750969" type="text/json">{"id":58750969,"first_name":"Stewart","last_name":"Martin","domain_name":"independent","page_name":"StewartMartin6","display_name":"Stewart Martin","profile_url":"https://independent.academia.edu/StewartMartin6?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_61610560 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="61610560"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 61610560, container: ".js-paper-rank-work_61610560", }); 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MSK1 and MSK2 are both nuclear serine/threonine protein kinases, with MSK1 being suggested to potentially play a role in breast cancer cell proliferation, cell cycle progression, cell migration, invasion and tumour growth. The aim of the current study was to assess MSK1 protein expression in breast cancer tumour specimens, evaluating its prognostic significance. A large cohort of 1902 early stage invasive breast cancer patients was used to explore the expression of MSK1. Protein expression was examined using standard immunohistochemistry on tissue microarrays. Low MSK1 protein expression was associated with younger age (P = 0.004), higher tumour grade (P \u0026lt; 0.001), higher Nottingham Prognostic Index scores (P = 0.007), negative ER (P \u0026lt; 0.001) and PR (P \u0026lt; 0.001) status, and with triple-negative (P \u0026lt; 0.001) and basal-like (P \u0026...","downloadable_attachments":[{"id":74590379,"asset_id":61610560,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":58750969,"first_name":"Stewart","last_name":"Martin","domain_name":"independent","page_name":"StewartMartin6","display_name":"Stewart Martin","profile_url":"https://independent.academia.edu/StewartMartin6?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10610,"name":"Survival 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data-work_id="13328868" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13328868/Dignity_in_the_terminally_ill_a_cross_sectional_cohort_study">Dignity in the terminally ill: a cross-sectional, cohort study</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13328868" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="198723bf1dd0c4177863726aa2f5ad1d" rel="nofollow" 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type="text/json">{"id":32570316,"first_name":"Thomas","last_name":"Hack","domain_name":"independent","page_name":"HackThomas","display_name":"Thomas Hack","profile_url":"https://independent.academia.edu/HackThomas?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-13328868">+2</span><div class="hidden js-additional-users-13328868"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/SusanMcClement">Susan McClement</a></span></div><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://umanitoba.academia.edu/HarveyChochinov">Harvey Chochinov</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-13328868'), placement: 'bottom', hide_delay: 200, 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Factors predicting outcome in cases of perfo-ration... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_51528446" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Peritonitis is caused most commonly by perforation of the hollow viscus and grave consequences of the dis-ease are attributed to the microbial infection of the perito-neal cavity. Factors predicting outcome in cases of perfo-ration peritonitis are well known and have been well ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51528446" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a3ffe274e9028e9ec479f9c9ef278b18" rel="nofollow" data-download="{"attachment_id":69216059,"asset_id":51528446,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69216059/download_file?st=MTczMjc1ODMxMCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="115111751" href="https://independent.academia.edu/ArpanMishra7">Arpan Mishra</a><script data-card-contents-for-user="115111751" type="text/json">{"id":115111751,"first_name":"Arpan","last_name":"Mishra","domain_name":"independent","page_name":"ArpanMishra7","display_name":"Arpan Mishra","profile_url":"https://independent.academia.edu/ArpanMishra7?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_51528446 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="51528446"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 51528446, container: ".js-paper-rank-work_51528446", }); 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href="https://www.academia.edu/30359838/Clinical_features_of_GH_deficiency_and_effects_of_3_years_of_GH_replacement_in_adults_with_controlled_Cushings_disease">Clinical features of GH deficiency and effects of 3 years of GH replacement in adults with controlled Cushing's disease</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/30359838" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="de7adebc86b29037aafcf4a9d4299799" rel="nofollow" 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modern healthcare system. Data collection and analysis are excessively time-consuming in everyday practice. The primary aim of our study was... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_73140595" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">BACKGROUND: Clinical audit has been increasingly required for the accreditation process in every modern healthcare system. Data collection and analysis are excessively time-consuming in everyday practice. 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itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="38900457" href="https://independent.academia.edu/MarciaAnselmo">Marcia Anselmo</a><script data-card-contents-for-user="38900457" type="text/json">{"id":38900457,"first_name":"Marcia","last_name":"Anselmo","domain_name":"independent","page_name":"MarciaAnselmo","display_name":"Marcia Anselmo","profile_url":"https://independent.academia.edu/MarciaAnselmo?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_75864081 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="75864081"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 75864081, container: ".js-paper-rank-work_75864081", }); });</script></li><li class="js-percentile-work_75864081 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window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=75864081]").text(description); $(".js-view-count-work_75864081").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_75864081").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="75864081"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="300" href="https://www.academia.edu/Documents/in/Mathematics">Mathematics</a>, <script data-card-contents-for-ri="300" type="text/json">{"id":300,"name":"Mathematics","url":"https://www.academia.edu/Documents/in/Mathematics?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4413" href="https://www.academia.edu/Documents/in/Educational_Measurement">Educational Measurement</a>, <script data-card-contents-for-ri="4413" type="text/json">{"id":4413,"name":"Educational Measurement","url":"https://www.academia.edu/Documents/in/Educational_Measurement?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="31465" href="https://www.academia.edu/Documents/in/Learning_Disabilities">Learning Disabilities</a><script data-card-contents-for-ri="31465" type="text/json">{"id":31465,"name":"Learning Disabilities","url":"https://www.academia.edu/Documents/in/Learning_Disabilities?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=75864081]'), work: {"id":75864081,"title":"Learning Problems in Kindergarten Students With Extremely Preterm Birth","created_at":"2022-04-08T18:47:30.147-07:00","url":"https://www.academia.edu/75864081/Learning_Problems_in_Kindergarten_Students_With_Extremely_Preterm_Birth?f_ri=1819400","dom_id":"work_75864081","summary":null,"downloadable_attachments":[{"id":83506165,"asset_id":75864081,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":38900457,"first_name":"Marcia","last_name":"Anselmo","domain_name":"independent","page_name":"MarciaAnselmo","display_name":"Marcia 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Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=1819400"},{"id":273520,"name":"Ohio","url":"https://www.academia.edu/Documents/in/Ohio?f_ri=1819400"},{"id":413194,"name":"Analysis of Variance","url":"https://www.academia.edu/Documents/in/Analysis_of_Variance?f_ri=1819400"},{"id":428130,"name":"Cognitive Ability","url":"https://www.academia.edu/Documents/in/Cognitive_Ability?f_ri=1819400"},{"id":452593,"name":"Learning Disorders","url":"https://www.academia.edu/Documents/in/Learning_Disorders?f_ri=1819400"},{"id":584601,"name":"Chi Square Distribution","url":"https://www.academia.edu/Documents/in/Chi_Square_Distribution?f_ri=1819400"},{"id":1294607,"name":"Logistic Models","url":"https://www.academia.edu/Documents/in/Logistic_Models?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=1819400"},{"id":3789883,"name":"Paediatrics and reproductive medicine","url":"https://www.academia.edu/Documents/in/Paediatrics_and_reproductive_medicine?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_74763046" data-work_id="74763046" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/74763046/Low_Dose_Isotretinoin_An_Option_for_Difficult_to_Treat_Papulopustular_Rosacea">Low-Dose Isotretinoin: An Option for Difficult-to-Treat Papulopustular Rosacea</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Rosacea is a chronic disease with a profound impact on quality of life. Although there are a range of treatments for its many manifestations, some cases are difficult to treat. Sbidian et al. show in this double-blind, randomized,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_74763046" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Rosacea is a chronic disease with a profound impact on quality of life. Although there are a range of treatments for its many manifestations, some cases are difficult to treat. Sbidian et al. show in this double-blind, randomized, placebo-controlled trial that low-dose isotretinoin can be effective in treating difficult-to-treat and frequently relapsing papulopustular rosacea.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/74763046" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a6388a65e68845bb62c8ab557b7310e7" rel="nofollow" data-download="{"attachment_id":82795482,"asset_id":74763046,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/82795482/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="344420" href="https://lumc.academia.edu/EsthervanZuuren">Esther van Zuuren</a><script data-card-contents-for-user="344420" type="text/json">{"id":344420,"first_name":"Esther","last_name":"van Zuuren","domain_name":"lumc","page_name":"EsthervanZuuren","display_name":"Esther van Zuuren","profile_url":"https://lumc.academia.edu/EsthervanZuuren?f_ri=1819400","photo":"https://0.academia-photos.com/344420/100452/56241579/s65_esther.van_zuuren.jpg"}</script></span></span></li><li class="js-paper-rank-work_74763046 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="74763046"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 74763046, container: ".js-paper-rank-work_74763046", }); });</script></li><li class="js-percentile-work_74763046 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 74763046; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_74763046"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_74763046 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="74763046"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 74763046; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=74763046]").text(description); $(".js-view-count-work_74763046").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_74763046").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="74763046"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="12426" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a>, <script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="86515" href="https://www.academia.edu/Documents/in/Rosacea">Rosacea</a><script data-card-contents-for-ri="86515" type="text/json">{"id":86515,"name":"Rosacea","url":"https://www.academia.edu/Documents/in/Rosacea?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=74763046]'), work: {"id":74763046,"title":"Low-Dose Isotretinoin: An Option for Difficult-to-Treat Papulopustular Rosacea","created_at":"2022-03-28T00:47:00.129-07:00","url":"https://www.academia.edu/74763046/Low_Dose_Isotretinoin_An_Option_for_Difficult_to_Treat_Papulopustular_Rosacea?f_ri=1819400","dom_id":"work_74763046","summary":"Rosacea is a chronic disease with a profound impact on quality of life. Although there are a range of treatments for its many manifestations, some cases are difficult to treat. Sbidian et al. show in this double-blind, randomized, placebo-controlled trial that low-dose isotretinoin can be effective in treating difficult-to-treat and frequently relapsing papulopustular rosacea.","downloadable_attachments":[{"id":82795482,"asset_id":74763046,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":344420,"first_name":"Esther","last_name":"van Zuuren","domain_name":"lumc","page_name":"EsthervanZuuren","display_name":"Esther van Zuuren","profile_url":"https://lumc.academia.edu/EsthervanZuuren?f_ri=1819400","photo":"https://0.academia-photos.com/344420/100452/56241579/s65_esther.van_zuuren.jpg"}],"research_interests":[{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=1819400","nofollow":false},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=1819400","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1819400","nofollow":false},{"id":86515,"name":"Rosacea","url":"https://www.academia.edu/Documents/in/Rosacea?f_ri=1819400","nofollow":false},{"id":194055,"name":"Randomised Controlled Trial","url":"https://www.academia.edu/Documents/in/Randomised_Controlled_Trial?f_ri=1819400"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=1819400"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=1819400"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=1819400"},{"id":564714,"name":"Isotretinoin","url":"https://www.academia.edu/Documents/in/Isotretinoin?f_ri=1819400"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=1819400"},{"id":2482506,"name":"Randomized Controlled Trials as Topic","url":"https://www.academia.edu/Documents/in/Randomized_Controlled_Trials_as_Topic?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_73257120" data-work_id="73257120" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/73257120/Analysis_of_blood_based_gene_expression_in_idiopathic_Parkinson_disease">Analysis of blood-based gene expression in idiopathic Parkinson disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective:To examine whether gene expression analysis of a large-scale Parkinson disease (PD) patient cohort produces a robust blood-based PD gene signature compared to previous studies that have used relatively small cohorts (≤220... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_73257120" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective:To examine whether gene expression analysis of a large-scale Parkinson disease (PD) patient cohort produces a robust blood-based PD gene signature compared to previous studies that have used relatively small cohorts (≤220 samples).Methods:Whole-blood gene expression profiles were collected from a total of 523 individuals. After preprocessing, the data contained 486 gene profiles (n = 205 PD, n = 233 controls, n = 48 other neurodegenerative diseases) that were partitioned into training, validation, and independent test cohorts to identify and validate a gene signature. Batch-effect reduction and cross-validation were performed to ensure signature reliability. Finally, functional and pathway enrichment analyses were applied to the signature to identify PD-associated gene networks.Results:A gene signature of 100 probes that mapped to 87 genes, corresponding to 64 upregulated and 23 downregulated genes differentiating between patients with idiopathic PD and controls, was ident...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/73257120" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="12b046fb3c8bc5f7eb3a77934f20be5f" rel="nofollow" data-download="{"attachment_id":81847780,"asset_id":73257120,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81847780/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="159390476" href="https://independent.academia.edu/ROnShamir">ROn Shamir</a><script data-card-contents-for-user="159390476" type="text/json">{"id":159390476,"first_name":"ROn","last_name":"Shamir","domain_name":"independent","page_name":"ROnShamir","display_name":"ROn Shamir","profile_url":"https://independent.academia.edu/ROnShamir?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_73257120 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="73257120"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 73257120, container: ".js-paper-rank-work_73257120", }); 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After preprocessing, the data contained 486 gene profiles (n = 205 PD, n = 233 controls, n = 48 other neurodegenerative diseases) that were partitioned into training, validation, and independent test cohorts to identify and validate a gene signature. Batch-effect reduction and cross-validation were performed to ensure signature reliability. Finally, functional and pathway enrichment analyses were applied to the signature to identify PD-associated gene networks.Results:A gene signature of 100 probes that mapped to 87 genes, corresponding to 64 upregulated and 23 downregulated genes differentiating between patients with idiopathic PD and controls, was ident...","downloadable_attachments":[{"id":81847780,"asset_id":73257120,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":159390476,"first_name":"ROn","last_name":"Shamir","domain_name":"independent","page_name":"ROnShamir","display_name":"ROn Shamir","profile_url":"https://independent.academia.edu/ROnShamir?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science?f_ri=1819400","nofollow":false},{"id":623,"name":"Neurology","url":"https://www.academia.edu/Documents/in/Neurology?f_ri=1819400","nofollow":false},{"id":6970,"name":"Biomarkers","url":"https://www.academia.edu/Documents/in/Biomarkers?f_ri=1819400","nofollow":false},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology?f_ri=1819400","nofollow":false},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1819400"},{"id":37848,"name":"Neurodegenerative Diseases","url":"https://www.academia.edu/Documents/in/Neurodegenerative_Diseases?f_ri=1819400"},{"id":43761,"name":"Transcriptome","url":"https://www.academia.edu/Documents/in/Transcriptome?f_ri=1819400"},{"id":194916,"name":"ROC Curve","url":"https://www.academia.edu/Documents/in/ROC_Curve?f_ri=1819400"},{"id":210852,"name":"Gene Regulatory Networks","url":"https://www.academia.edu/Documents/in/Gene_Regulatory_Networks?f_ri=1819400"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=1819400"},{"id":375301,"name":"Microarray Analysis","url":"https://www.academia.edu/Documents/in/Microarray_Analysis?f_ri=1819400"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results?f_ri=1819400"},{"id":1239755,"name":"Neurosciences","url":"https://www.academia.edu/Documents/in/Neurosciences?f_ri=1819400"},{"id":1541077,"name":"Parkinson Disease","url":"https://www.academia.edu/Documents/in/Parkinson_Disease?f_ri=1819400"},{"id":1810445,"name":"Gene expression profiling","url":"https://www.academia.edu/Documents/in/Gene_expression_profiling?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_73185237" data-work_id="73185237" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/73185237/Reliability_and_Validity_of_the_Tinetti_Mobility_Test_for_Individuals_With_Parkinson_Disease">Reliability and Validity of the Tinetti Mobility Test for Individuals With Parkinson Disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Background and Purpose This study examined the interrater and intrarater reliability, concurrent validity, and criterion validity of the Tinetti Mobility Test (TMT) as a fall risk screening tool in individuals with Parkinson disease (PD).... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_73185237" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Background and Purpose This study examined the interrater and intrarater reliability, concurrent validity, and criterion validity of the Tinetti Mobility Test (TMT) as a fall risk screening tool in individuals with Parkinson disease (PD). Subjects Thirty individuals with PD voluntarily participated in the study, and data from a retrospective review of 126 patient records were included. Methods Physical therapists and physical therapist students rated live and videotaped performances of the TMT. Tinetti Mobility Test scores were correlated with Unified Parkinson&#39;s Disease Rating Scale (UPDRS) motor scores and comfortable gait speed. The ability of the TMT to accurately assess fall risk was determined. Results Interrater and intrarater reliability was good to excellent (intraclass correlation coefficient of &gt;.80). Tinetti Mobility Test scores correlated with UPDRS motor scores (rs=−.45) and gait speed (rs=.53). The sensitivity and specificity of the TMT to identify fallers were...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/73185237" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="95fd55bd068b88a5038fa3f635ae0a3e" rel="nofollow" data-download="{"attachment_id":81803643,"asset_id":73185237,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81803643/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50057548" href="https://independent.academia.edu/DebKegelmeyer">Deb Kegelmeyer</a><script data-card-contents-for-user="50057548" type="text/json">{"id":50057548,"first_name":"Deb","last_name":"Kegelmeyer","domain_name":"independent","page_name":"DebKegelmeyer","display_name":"Deb Kegelmeyer","profile_url":"https://independent.academia.edu/DebKegelmeyer?f_ri=1819400","photo":"https://0.academia-photos.com/50057548/103039651/92211556/s65_deb.kegelmeyer.jpeg"}</script></span></span></li><li class="js-paper-rank-work_73185237 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="73185237"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 73185237, container: ".js-paper-rank-work_73185237", }); 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Subjects Thirty individuals with PD voluntarily participated in the study, and data from a retrospective review of 126 patient records were included. Methods Physical therapists and physical therapist students rated live and videotaped performances of the TMT. Tinetti Mobility Test scores were correlated with Unified Parkinson\u0026#39;s Disease Rating Scale (UPDRS) motor scores and comfortable gait speed. The ability of the TMT to accurately assess fall risk was determined. Results Interrater and intrarater reliability was good to excellent (intraclass correlation coefficient of \u0026gt;.80). Tinetti Mobility Test scores correlated with UPDRS motor scores (rs=−.45) and gait speed (rs=.53). The sensitivity and specificity of the TMT to identify fallers were...","downloadable_attachments":[{"id":81803643,"asset_id":73185237,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50057548,"first_name":"Deb","last_name":"Kegelmeyer","domain_name":"independent","page_name":"DebKegelmeyer","display_name":"Deb Kegelmeyer","profile_url":"https://independent.academia.edu/DebKegelmeyer?f_ri=1819400","photo":"https://0.academia-photos.com/50057548/103039651/92211556/s65_deb.kegelmeyer.jpeg"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=1819400","nofollow":false},{"id":32473,"name":"Physical Therapy","url":"https://www.academia.edu/Documents/in/Physical_Therapy?f_ri=1819400","nofollow":false},{"id":60256,"name":"Gait","url":"https://www.academia.edu/Documents/in/Gait?f_ri=1819400","nofollow":false},{"id":244814,"name":"Clinical 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type="text/json">{"id":631,"name":"Pediatrics","url":"https://www.academia.edu/Documents/in/Pediatrics?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="1062" href="https://www.academia.edu/Documents/in/Special_Education">Special Education</a>, <script data-card-contents-for-ri="1062" type="text/json">{"id":1062,"name":"Special Education","url":"https://www.academia.edu/Documents/in/Special_Education?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="5097" href="https://www.academia.edu/Documents/in/Blindness">Blindness</a>, <script data-card-contents-for-ri="5097" type="text/json">{"id":5097,"name":"Blindness","url":"https://www.academia.edu/Documents/in/Blindness?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17845" href="https://www.academia.edu/Documents/in/Cerebral_Palsy">Cerebral Palsy</a><script data-card-contents-for-ri="17845" 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factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=1819400"},{"id":248366,"name":"New York","url":"https://www.academia.edu/Documents/in/New_York?f_ri=1819400"},{"id":253560,"name":"Newborn Infant","url":"https://www.academia.edu/Documents/in/Newborn_Infant?f_ri=1819400"},{"id":313857,"name":"Risk Factor","url":"https://www.academia.edu/Documents/in/Risk_Factor?f_ri=1819400"},{"id":402446,"name":"Maternal Age","url":"https://www.academia.edu/Documents/in/Maternal_Age?f_ri=1819400"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=1819400"},{"id":1537664,"name":"Psychomotor Development","url":"https://www.academia.edu/Documents/in/Psychomotor_Development?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":3651718,"name":"Premature infant","url":"https://www.academia.edu/Documents/in/Premature_infant?f_ri=1819400"},{"id":3789883,"name":"Paediatrics and reproductive medicine","url":"https://www.academia.edu/Documents/in/Paediatrics_and_reproductive_medicine?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_62729842" data-work_id="62729842" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/62729842/Comprehensive_Risk_Assessments_of_Diabetic_Patients_from_7_Asian_Countries_The_Joint_Asia_Diabetes_Evaluation_JADE_Program">Comprehensive Risk Assessments of Diabetic Patients from 7 Asian Countries: The Joint Asia Diabetes Evaluation (JADE) Program</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This is an Accepted Article that has been peer-reviewed and approved for publication in the Journal of Diabetes, but has yet to undergo copy-editing and proof correction. Please cite this article as an Accepted Article; doi:... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_62729842" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This is an Accepted Article that has been peer-reviewed and approved for publication in the Journal of Diabetes, but has yet to undergo copy-editing and proof correction. Please cite this article as an Accepted Article; doi: 10.1111/j.1753-0407.2011.00115.x ... Comprehensive Risk ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/62729842" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e111b0e62a5700763d1ea581988c9217" rel="nofollow" data-download="{"attachment_id":75400908,"asset_id":62729842,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75400908/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="66641813" href="https://independent.academia.edu/THimathongkam">Thep Himathongkam</a><script data-card-contents-for-user="66641813" type="text/json">{"id":66641813,"first_name":"Thep","last_name":"Himathongkam","domain_name":"independent","page_name":"THimathongkam","display_name":"Thep Himathongkam","profile_url":"https://independent.academia.edu/THimathongkam?f_ri=1819400","photo":"https://0.academia-photos.com/66641813/37984972/31944467/s65_thep.himathongkam.jpg"}</script></span></span></li><li class="js-paper-rank-work_62729842 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="62729842"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 62729842, container: ".js-paper-rank-work_62729842", }); 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$(".js-view-count[data-work-id=62729842]").text(description); $(".js-view-count-work_62729842").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_62729842").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="62729842"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="4581" href="https://www.academia.edu/Documents/in/Diabetes">Diabetes</a>, <script data-card-contents-for-ri="4581" type="text/json">{"id":4581,"name":"Diabetes","url":"https://www.academia.edu/Documents/in/Diabetes?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a>, <script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="110578" href="https://www.academia.edu/Documents/in/Asia">Asia</a><script data-card-contents-for-ri="110578" type="text/json">{"id":110578,"name":"Asia","url":"https://www.academia.edu/Documents/in/Asia?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=62729842]'), work: {"id":62729842,"title":"Comprehensive Risk Assessments of Diabetic Patients from 7 Asian Countries: The Joint Asia Diabetes Evaluation (JADE) Program","created_at":"2021-11-29T19:52:22.826-08:00","url":"https://www.academia.edu/62729842/Comprehensive_Risk_Assessments_of_Diabetic_Patients_from_7_Asian_Countries_The_Joint_Asia_Diabetes_Evaluation_JADE_Program?f_ri=1819400","dom_id":"work_62729842","summary":"This is an Accepted Article that has been peer-reviewed and approved for publication in the Journal of Diabetes, but has yet to undergo copy-editing and proof correction. 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Comprehensive Risk ...","downloadable_attachments":[{"id":75400908,"asset_id":62729842,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":66641813,"first_name":"Thep","last_name":"Himathongkam","domain_name":"independent","page_name":"THimathongkam","display_name":"Thep Himathongkam","profile_url":"https://independent.academia.edu/THimathongkam?f_ri=1819400","photo":"https://0.academia-photos.com/66641813/37984972/31944467/s65_thep.himathongkam.jpg"}],"research_interests":[{"id":4581,"name":"Diabetes","url":"https://www.academia.edu/Documents/in/Diabetes?f_ri=1819400","nofollow":false},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=1819400","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false},{"id":110578,"name":"Asia","url":"https://www.academia.edu/Documents/in/Asia?f_ri=1819400","nofollow":false},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=1819400"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=1819400"},{"id":209856,"name":"Registries","url":"https://www.academia.edu/Documents/in/Registries?f_ri=1819400"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=1819400"},{"id":420633,"name":"Diabetes complications","url":"https://www.academia.edu/Documents/in/Diabetes_complications?f_ri=1819400"},{"id":570668,"name":"Urban Population","url":"https://www.academia.edu/Documents/in/Urban_Population?f_ri=1819400"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=1819400"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=1819400"},{"id":915951,"name":"Type 2 Diabetes Mellitus","url":"https://www.academia.edu/Documents/in/Type_2_Diabetes_Mellitus?f_ri=1819400"},{"id":1191356,"name":"Internet","url":"https://www.academia.edu/Documents/in/Internet?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_61217454" data-work_id="61217454" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/61217454/Methadone_Treatment_for_HIV_Prevention_Feasibility_Retention_and_Predictors_of_Attrition_in_Dar_es_Salaam_Tanzania_A_Retrospective_Cohort_Study">Methadone Treatment for HIV Prevention--Feasibility, Retention, and Predictors of Attrition in Dar es Salaam, Tanzania: A Retrospective Cohort Study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">People who inject drugs (PWID) in Dar es Salaam, Tanzania, have an estimated human immunodeficiency virus (HIV) prevalence of 42%-50% compared with 6.9% among the general population. Extensive evidence supports methadone maintenance to... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_61217454" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">People who inject drugs (PWID) in Dar es Salaam, Tanzania, have an estimated human immunodeficiency virus (HIV) prevalence of 42%-50% compared with 6.9% among the general population. Extensive evidence supports methadone maintenance to lower morbidity, mortality, and transmission of HIV and other infectious diseases among PWID. In 2011, the Tanzanian government launched the first publicly funded methadone clinic on the mainland of sub-Saharan Africa at Muhimbili National Hospital. We conducted a retrospective cohort study of methadone-naive patients enrolling into methadone maintenance treatment. Kaplan-Meier survival curves were constructed to assess retention probability. Proportional hazards regression models were used to evaluate the association of characteristics with attrition from the methadone program. Overall, 629 PWID enrolled into methadone treatment during the study. At 12 months, the proportion of clients retained in care was 57% (95% confidence interval [CI], 53%-62%). Compared with those receiving a low dose (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;40 mg), clients receiving a medium (40-85 mg) (adjusted hazard ratio [aHR], 0.50 [95% CI, .37-.68]) and high (&amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;85 mg) (aHR, 0.41 [95% CI, .29-.59]) dose of methadone had a lower likelihood of attrition, adjusting for other characteristics. Older clients (aHR, 0.53 per 10 years [95% CI, .42-.69]) and female clients (aHR, 0.50 [95% CI, .28-.90]) had a significantly lower likelihood of attrition, whereas clients who reported a history of sexual abuse (aHR, 2.84 [95% CI, 1.24-6.51]) had a significantly higher likelihood of attrition. Patient retention in methadone maintenance is comparable to estimates from programs in North America, Europe, and Asia. Future implementation strategies should focus on higher doses and flexible dosing strategies to optimize program retention and strengthened efforts for clients at higher risk of attrition.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/61217454" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="207722458" href="https://independent.academia.edu/PamelaKaduri">Pamela Kaduri</a><script data-card-contents-for-user="207722458" type="text/json">{"id":207722458,"first_name":"Pamela","last_name":"Kaduri","domain_name":"independent","page_name":"PamelaKaduri","display_name":"Pamela Kaduri","profile_url":"https://independent.academia.edu/PamelaKaduri?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_61217454 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="61217454"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 61217454, container: ".js-paper-rank-work_61217454", }); 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$(".js-view-count[data-work-id=61217454]").text(description); $(".js-view-count-work_61217454").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_61217454").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="61217454"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">12</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="8819" href="https://www.academia.edu/Documents/in/Medication_Adherence">Medication Adherence</a>, <script data-card-contents-for-ri="8819" type="text/json">{"id":8819,"name":"Medication Adherence","url":"https://www.academia.edu/Documents/in/Medication_Adherence?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="23241" href="https://www.academia.edu/Documents/in/Tanzania">Tanzania</a>, <script data-card-contents-for-ri="23241" type="text/json">{"id":23241,"name":"Tanzania","url":"https://www.academia.edu/Documents/in/Tanzania?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a>, <script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="133057" href="https://www.academia.edu/Documents/in/Young_Adult">Young Adult</a><script data-card-contents-for-ri="133057" type="text/json">{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=61217454]'), work: {"id":61217454,"title":"Methadone Treatment for HIV Prevention--Feasibility, Retention, and Predictors of Attrition in Dar es Salaam, Tanzania: A Retrospective Cohort Study","created_at":"2021-11-07T10:55:55.054-08:00","url":"https://www.academia.edu/61217454/Methadone_Treatment_for_HIV_Prevention_Feasibility_Retention_and_Predictors_of_Attrition_in_Dar_es_Salaam_Tanzania_A_Retrospective_Cohort_Study?f_ri=1819400","dom_id":"work_61217454","summary":"People who inject drugs (PWID) in Dar es Salaam, Tanzania, have an estimated human immunodeficiency virus (HIV) prevalence of 42%-50% compared with 6.9% among the general population. Extensive evidence supports methadone maintenance to lower morbidity, mortality, and transmission of HIV and other infectious diseases among PWID. In 2011, the Tanzanian government launched the first publicly funded methadone clinic on the mainland of sub-Saharan Africa at Muhimbili National Hospital. We conducted a retrospective cohort study of methadone-naive patients enrolling into methadone maintenance treatment. Kaplan-Meier survival curves were constructed to assess retention probability. Proportional hazards regression models were used to evaluate the association of characteristics with attrition from the methadone program. Overall, 629 PWID enrolled into methadone treatment during the study. At 12 months, the proportion of clients retained in care was 57% (95% confidence interval [CI], 53%-62%). Compared with those receiving a low dose (\u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;lt;40 mg), clients receiving a medium (40-85 mg) (adjusted hazard ratio [aHR], 0.50 [95% CI, .37-.68]) and high (\u0026amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;amp;gt;85 mg) (aHR, 0.41 [95% CI, .29-.59]) dose of methadone had a lower likelihood of attrition, adjusting for other characteristics. Older clients (aHR, 0.53 per 10 years [95% CI, .42-.69]) and female clients (aHR, 0.50 [95% CI, .28-.90]) had a significantly lower likelihood of attrition, whereas clients who reported a history of sexual abuse (aHR, 2.84 [95% CI, 1.24-6.51]) had a significantly higher likelihood of attrition. Patient retention in methadone maintenance is comparable to estimates from programs in North America, Europe, and Asia. Future implementation strategies should focus on higher doses and flexible dosing strategies to optimize program retention and strengthened efforts for clients at higher risk of attrition.","downloadable_attachments":[],"ordered_authors":[{"id":207722458,"first_name":"Pamela","last_name":"Kaduri","domain_name":"independent","page_name":"PamelaKaduri","display_name":"Pamela Kaduri","profile_url":"https://independent.academia.edu/PamelaKaduri?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":8819,"name":"Medication Adherence","url":"https://www.academia.edu/Documents/in/Medication_Adherence?f_ri=1819400","nofollow":false},{"id":23241,"name":"Tanzania","url":"https://www.academia.edu/Documents/in/Tanzania?f_ri=1819400","nofollow":false},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=1819400","nofollow":false},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=1819400","nofollow":false},{"id":174502,"name":"Incidence","url":"https://www.academia.edu/Documents/in/Incidence?f_ri=1819400"},{"id":361527,"name":"Methadone","url":"https://www.academia.edu/Documents/in/Methadone?f_ri=1819400"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=1819400"},{"id":1336838,"name":"Clinical Infectious Diseases","url":"https://www.academia.edu/Documents/in/Clinical_Infectious_Diseases?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":3686524,"name":"Opiate substitution treatment","url":"https://www.academia.edu/Documents/in/Opiate_substitution_treatment?f_ri=1819400"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=1819400"},{"id":3887581,"name":"HIV infections","url":"https://www.academia.edu/Documents/in/HIV_infections?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_60759791" data-work_id="60759791" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/60759791/Epidemiology_of_medication_related_problems_in_children_with_kidney_disease">Epidemiology of medication-related problems in children with kidney disease</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/60759791" data-share-source="work_strip" 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itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="198732983" href="https://independent.academia.edu/DRNORKASIHANIBRAHIM">DR NORKASIHAN IBRAHIM</a><script data-card-contents-for-user="198732983" type="text/json">{"id":198732983,"first_name":"DR NORKASIHAN","last_name":"IBRAHIM","domain_name":"independent","page_name":"DRNORKASIHANIBRAHIM","display_name":"DR NORKASIHAN IBRAHIM","profile_url":"https://independent.academia.edu/DRNORKASIHANIBRAHIM?f_ri=1819400","photo":"https://0.academia-photos.com/198732983/60578616/48842062/s65_dr_norkasihan.ibrahim.jpeg"}</script></span></span></li><li class="js-paper-rank-work_60759791 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="60759791"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 60759791, 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window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=60759791]").text(description); $(".js-view-count-work_60759791").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_60759791").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="60759791"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="8999" href="https://www.academia.edu/Documents/in/Kidney_diseases">Kidney diseases</a>, <script data-card-contents-for-ri="8999" type="text/json">{"id":8999,"name":"Kidney diseases","url":"https://www.academia.edu/Documents/in/Kidney_diseases?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="134346" href="https://www.academia.edu/Documents/in/Infant">Infant</a><script data-card-contents-for-ri="134346" type="text/json">{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=60759791]'), work: {"id":60759791,"title":"Epidemiology of medication-related problems in children with kidney disease","created_at":"2021-11-01T20:43:51.140-07:00","url":"https://www.academia.edu/60759791/Epidemiology_of_medication_related_problems_in_children_with_kidney_disease?f_ri=1819400","dom_id":"work_60759791","summary":null,"downloadable_attachments":[{"id":74059920,"asset_id":60759791,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":198732983,"first_name":"DR NORKASIHAN","last_name":"IBRAHIM","domain_name":"independent","page_name":"DRNORKASIHANIBRAHIM","display_name":"DR NORKASIHAN IBRAHIM","profile_url":"https://independent.academia.edu/DRNORKASIHANIBRAHIM?f_ri=1819400","photo":"https://0.academia-photos.com/198732983/60578616/48842062/s65_dr_norkasihan.ibrahim.jpeg"}],"research_interests":[{"id":8999,"name":"Kidney diseases","url":"https://www.academia.edu/Documents/in/Kidney_diseases?f_ri=1819400","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=1819400","nofollow":false},{"id":134346,"name":"Infant","url":"https://www.academia.edu/Documents/in/Infant?f_ri=1819400","nofollow":false},{"id":175243,"name":"Pediatric Nephrology","url":"https://www.academia.edu/Documents/in/Pediatric_Nephrology?f_ri=1819400"},{"id":291274,"name":"Great Britain","url":"https://www.academia.edu/Documents/in/Great_Britain?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":2489700,"name":"Child preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=1819400"},{"id":3789883,"name":"Paediatrics and reproductive medicine","url":"https://www.academia.edu/Documents/in/Paediatrics_and_reproductive_medicine?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_58636583" data-work_id="58636583" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/58636583/New_Measure_of_Insulin_Sensitivity_Predicts_Cardiovascular_Disease_Better_than_HOMA_Estimated_Insulin_Resistance">New Measure of Insulin Sensitivity Predicts Cardiovascular Disease Better than HOMA Estimated Insulin Resistance</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/58636583" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="5cb424d00ebcc196f0b56a3f8412d0ba" rel="nofollow" data-download="{"attachment_id":72950756,"asset_id":58636583,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" 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Zagorodnov","profile_url":"https://nanyang.academia.edu/VitaliZagorodnov?f_ri=1819400","photo":"https://0.academia-photos.com/830600/290395/343534/s65_vitali.zagorodnov.jpg"}</script></span></span></li><li class="js-paper-rank-work_58636583 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="58636583"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 58636583, container: ".js-paper-rank-work_58636583", }); });</script></li><li class="js-percentile-work_58636583 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 58636583; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = 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style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="58636583"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="5018" href="https://www.academia.edu/Documents/in/Anthropometry">Anthropometry</a>, <script data-card-contents-for-ri="5018" type="text/json">{"id":5018,"name":"Anthropometry","url":"https://www.academia.edu/Documents/in/Anthropometry?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="16664" href="https://www.academia.edu/Documents/in/Risk_assessment">Risk assessment</a>, <script data-card-contents-for-ri="16664" type="text/json">{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="28235" href="https://www.academia.edu/Documents/in/Multidisciplinary">Multidisciplinary</a>, <script data-card-contents-for-ri="28235" type="text/json">{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="28850" href="https://www.academia.edu/Documents/in/Linear_models">Linear models</a><script data-card-contents-for-ri="28850" type="text/json">{"id":28850,"name":"Linear models","url":"https://www.academia.edu/Documents/in/Linear_models?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=58636583]'), work: {"id":58636583,"title":"New Measure of Insulin Sensitivity Predicts Cardiovascular Disease Better than HOMA Estimated Insulin Resistance","created_at":"2021-10-17T11:21:28.583-07:00","url":"https://www.academia.edu/58636583/New_Measure_of_Insulin_Sensitivity_Predicts_Cardiovascular_Disease_Better_than_HOMA_Estimated_Insulin_Resistance?f_ri=1819400","dom_id":"work_58636583","summary":null,"downloadable_attachments":[{"id":72950756,"asset_id":58636583,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":830600,"first_name":"Vitali","last_name":"Zagorodnov","domain_name":"nanyang","page_name":"VitaliZagorodnov","display_name":"Vitali Zagorodnov","profile_url":"https://nanyang.academia.edu/VitaliZagorodnov?f_ri=1819400","photo":"https://0.academia-photos.com/830600/290395/343534/s65_vitali.zagorodnov.jpg"}],"research_interests":[{"id":5018,"name":"Anthropometry","url":"https://www.academia.edu/Documents/in/Anthropometry?f_ri=1819400","nofollow":false},{"id":16664,"name":"Risk assessment","url":"https://www.academia.edu/Documents/in/Risk_assessment?f_ri=1819400","nofollow":false},{"id":28235,"name":"Multidisciplinary","url":"https://www.academia.edu/Documents/in/Multidisciplinary?f_ri=1819400","nofollow":false},{"id":28850,"name":"Linear models","url":"https://www.academia.edu/Documents/in/Linear_models?f_ri=1819400","nofollow":false},{"id":51373,"name":"Insulin Resistance","url":"https://www.academia.edu/Documents/in/Insulin_Resistance?f_ri=1819400"},{"id":194916,"name":"ROC Curve","url":"https://www.academia.edu/Documents/in/ROC_Curve?f_ri=1819400"},{"id":220780,"name":"PLoS one","url":"https://www.academia.edu/Documents/in/PLoS_one?f_ri=1819400"},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=1819400"},{"id":559242,"name":"Cardiovascular Diseases","url":"https://www.academia.edu/Documents/in/Cardiovascular_Diseases?f_ri=1819400"},{"id":622589,"name":"Risk Assessment","url":"https://www.academia.edu/Documents/in/Risk_Assessment-2?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_58316150" data-work_id="58316150" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/58316150/The_Belgian_Systemic_Sclerosis_Cohort_Correlations_Between_Disease_Severity_Scores_Cutaneous_Subsets_and_Autoantibody_Profile">The Belgian Systemic Sclerosis Cohort: Correlations Between Disease Severity Scores, Cutaneous Subsets, and Autoantibody Profile</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective.To report baseline and followup data on the first 438 patients with systemic sclerosis (SSc) included in the Belgian Systemic Sclerosis Cohort.Methods.According to LeRoy and Medsger’s classification, 73 patients with limited SSc... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_58316150" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective.To report baseline and followup data on the first 438 patients with systemic sclerosis (SSc) included in the Belgian Systemic Sclerosis Cohort.Methods.According to LeRoy and Medsger’s classification, 73 patients with limited SSc (lSSc), 279 with limited cutaneous SSc (lcSSc), and 86 with diffuse cutaneous SSc (dcSSc) were included. History was collected and clinical examination, blood tests, and paraclinical investigations were repeated. The Disease Activity Score (DAS) and Disease Severity Score (DSS) of several organ systems were computed. An organ system was considered to demonstrate SSc if the corresponding DSS was ≥ 1.Results.At baseline, patients with dcSSc had more general, joint/tendon, muscle, gastrointestinal, and kidney involvement. Mean DLCO was below normal in patients with lSSc, indicating unsuspected lung involvement. Patients with anti-Scl-70 had more vascular, skin, joint/tendon, and lung involvement. Patients with anti-RNA polymerase III had more skin and...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/58316150" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="abae13d99c2add103db65fbebdbc9cf3" rel="nofollow" data-download="{"attachment_id":72787950,"asset_id":58316150,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/72787950/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35589397" href="https://independent.academia.edu/ElieCogan">Elie Cogan</a><script data-card-contents-for-user="35589397" type="text/json">{"id":35589397,"first_name":"Elie","last_name":"Cogan","domain_name":"independent","page_name":"ElieCogan","display_name":"Elie Cogan","profile_url":"https://independent.academia.edu/ElieCogan?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_58316150 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="58316150"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 58316150, container: ".js-paper-rank-work_58316150", }); 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$(".js-view-count[data-work-id=58316150]").text(description); $(".js-view-count-work_58316150").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_58316150").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="58316150"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1290" href="https://www.academia.edu/Documents/in/Immunology">Immunology</a>, <script data-card-contents-for-ri="1290" type="text/json">{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="40862" href="https://www.academia.edu/Documents/in/Belgium">Belgium</a>, <script data-card-contents-for-ri="40862" type="text/json">{"id":40862,"name":"Belgium","url":"https://www.academia.edu/Documents/in/Belgium?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="137516" href="https://www.academia.edu/Documents/in/Follow-up_studies">Follow-up studies</a>, <script data-card-contents-for-ri="137516" type="text/json">{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=58316150]'), work: {"id":58316150,"title":"The Belgian Systemic Sclerosis Cohort: Correlations Between Disease Severity Scores, Cutaneous Subsets, and Autoantibody Profile","created_at":"2021-10-16T00:56:41.789-07:00","url":"https://www.academia.edu/58316150/The_Belgian_Systemic_Sclerosis_Cohort_Correlations_Between_Disease_Severity_Scores_Cutaneous_Subsets_and_Autoantibody_Profile?f_ri=1819400","dom_id":"work_58316150","summary":"Objective.To report baseline and followup data on the first 438 patients with systemic sclerosis (SSc) included in the Belgian Systemic Sclerosis Cohort.Methods.According to LeRoy and Medsger’s classification, 73 patients with limited SSc (lSSc), 279 with limited cutaneous SSc (lcSSc), and 86 with diffuse cutaneous SSc (dcSSc) were included. History was collected and clinical examination, blood tests, and paraclinical investigations were repeated. The Disease Activity Score (DAS) and Disease Severity Score (DSS) of several organ systems were computed. An organ system was considered to demonstrate SSc if the corresponding DSS was ≥ 1.Results.At baseline, patients with dcSSc had more general, joint/tendon, muscle, gastrointestinal, and kidney involvement. Mean DLCO was below normal in patients with lSSc, indicating unsuspected lung involvement. Patients with anti-Scl-70 had more vascular, skin, joint/tendon, and lung involvement. Patients with anti-RNA polymerase III had more skin and...","downloadable_attachments":[{"id":72787950,"asset_id":58316150,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35589397,"first_name":"Elie","last_name":"Cogan","domain_name":"independent","page_name":"ElieCogan","display_name":"Elie Cogan","profile_url":"https://independent.academia.edu/ElieCogan?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1290,"name":"Immunology","url":"https://www.academia.edu/Documents/in/Immunology?f_ri=1819400","nofollow":false},{"id":40862,"name":"Belgium","url":"https://www.academia.edu/Documents/in/Belgium?f_ri=1819400","nofollow":false},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=1819400","nofollow":false},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=1819400","nofollow":false},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=1819400"},{"id":410370,"name":"Public health systems and services research","url":"https://www.academia.edu/Documents/in/Public_health_systems_and_services_research-1?f_ri=1819400"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=1819400"},{"id":584615,"name":"Disease Progression","url":"https://www.academia.edu/Documents/in/Disease_Progression?f_ri=1819400"},{"id":670043,"name":"Joints","url":"https://www.academia.edu/Documents/in/Joints?f_ri=1819400"},{"id":1482586,"name":"Autoantibodies","url":"https://www.academia.edu/Documents/in/Autoantibodies?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":2463800,"name":"Severity of Illness Index","url":"https://www.academia.edu/Documents/in/Severity_of_Illness_Index?f_ri=1819400"},{"id":3063336,"name":"Respiratory function tests","url":"https://www.academia.edu/Documents/in/Respiratory_function_tests?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_55924474" data-work_id="55924474" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/55924474/Attention_Deficit_Hyperactivity_Disorder_Trajectories_From_Childhood_to_Young_Adulthood">Attention-Deficit/Hyperactivity Disorder Trajectories From Childhood to Young Adulthood</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/55924474" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="dcbd12fc81bcb6d1e100e83a0eee70db" rel="nofollow" data-download="{"attachment_id":71563104,"asset_id":55924474,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/71563104/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3164025" href="https://uci.academia.edu/JamesSwanson">James Swanson</a><script data-card-contents-for-user="3164025" type="text/json">{"id":3164025,"first_name":"James","last_name":"Swanson","domain_name":"uci","page_name":"JamesSwanson","display_name":"James Swanson","profile_url":"https://uci.academia.edu/JamesSwanson?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_55924474 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="55924474"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 55924474, container: ".js-paper-rank-work_55924474", }); });</script></li><li class="js-percentile-work_55924474 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 55924474; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_55924474"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_55924474 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="55924474"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 55924474; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=55924474]").text(description); $(".js-view-count-work_55924474").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_55924474").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="55924474"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="9821" href="https://www.academia.edu/Documents/in/Brazil">Brazil</a>, <script data-card-contents-for-ri="9821" type="text/json">{"id":9821,"name":"Brazil","url":"https://www.academia.edu/Documents/in/Brazil?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="64933" href="https://www.academia.edu/Documents/in/Child">Child</a>, <script data-card-contents-for-ri="64933" type="text/json">{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="133057" href="https://www.academia.edu/Documents/in/Young_Adult">Young Adult</a><script data-card-contents-for-ri="133057" type="text/json">{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=55924474]'), work: {"id":55924474,"title":"Attention-Deficit/Hyperactivity Disorder Trajectories From Childhood to Young Adulthood","created_at":"2021-10-06T05:16:48.997-07:00","url":"https://www.academia.edu/55924474/Attention_Deficit_Hyperactivity_Disorder_Trajectories_From_Childhood_to_Young_Adulthood?f_ri=1819400","dom_id":"work_55924474","summary":null,"downloadable_attachments":[{"id":71563104,"asset_id":55924474,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3164025,"first_name":"James","last_name":"Swanson","domain_name":"uci","page_name":"JamesSwanson","display_name":"James Swanson","profile_url":"https://uci.academia.edu/JamesSwanson?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":9821,"name":"Brazil","url":"https://www.academia.edu/Documents/in/Brazil?f_ri=1819400","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false},{"id":64933,"name":"Child","url":"https://www.academia.edu/Documents/in/Child?f_ri=1819400","nofollow":false},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=1819400","nofollow":false},{"id":330953,"name":"Longitudinal Studies","url":"https://www.academia.edu/Documents/in/Longitudinal_Studies?f_ri=1819400"},{"id":546419,"name":"Age Factors","url":"https://www.academia.edu/Documents/in/Age_Factors?f_ri=1819400"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=1819400"},{"id":2526151,"name":"Attention deficit disorder with hyperactivity","url":"https://www.academia.edu/Documents/in/Attention_deficit_disorder_with_hyperactivity?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_53422628" data-work_id="53422628" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/53422628/Psychiatric_Disorders_in_Adolescents_With_Single_Ventricle_Congenital_Heart_Disease">Psychiatric Disorders in Adolescents With Single Ventricle Congenital Heart Disease</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Mental health outcomes for survivors of critical congenital heart disease (CHD) remain under-investigated. We sought to examine psychiatric disorders and psychosocial functioning in adolescents with single ventricle CHD and to explore... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_53422628" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Mental health outcomes for survivors of critical congenital heart disease (CHD) remain under-investigated. We sought to examine psychiatric disorders and psychosocial functioning in adolescents with single ventricle CHD and to explore whether patient-related risk factors predict dysfunction. This cohort study recruited 156 adolescents with single ventricle CHD who underwent the Fontan procedure and 111 healthy referents. Participants underwent comprehensive psychiatric evaluation including a clinician-rated psychiatric interview and parent- and self-report ratings of anxiety, disruptive behavior, including attention-deficit/hyperactivity disorder (ADHD), and depressive symptoms. Risk factors for dysfunction included IQ, medical characteristics, and concurrent brain abnormalities. Adolescents with single ventricle CHD had higher rates of lifetime psychiatric diagnosis compared with referents (CHD: 65%, referent: 22%; P &lt; .001). Specifically, they had higher rates of lifetime anxie...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/53422628" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a9e401e01e2ded87be656da4f9bd4357" rel="nofollow" data-download="{"attachment_id":70274429,"asset_id":53422628,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/70274429/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37546078" href="https://independent.academia.edu/MichaelRivkin">Michael Rivkin</a><script data-card-contents-for-user="37546078" type="text/json">{"id":37546078,"first_name":"Michael","last_name":"Rivkin","domain_name":"independent","page_name":"MichaelRivkin","display_name":"Michael Rivkin","profile_url":"https://independent.academia.edu/MichaelRivkin?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_53422628 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="53422628"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 53422628, container: ".js-paper-rank-work_53422628", }); 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We sought to examine psychiatric disorders and psychosocial functioning in adolescents with single ventricle CHD and to explore whether patient-related risk factors predict dysfunction. This cohort study recruited 156 adolescents with single ventricle CHD who underwent the Fontan procedure and 111 healthy referents. Participants underwent comprehensive psychiatric evaluation including a clinician-rated psychiatric interview and parent- and self-report ratings of anxiety, disruptive behavior, including attention-deficit/hyperactivity disorder (ADHD), and depressive symptoms. Risk factors for dysfunction included IQ, medical characteristics, and concurrent brain abnormalities. Adolescents with single ventricle CHD had higher rates of lifetime psychiatric diagnosis compared with referents (CHD: 65%, referent: 22%; P \u0026lt; .001). Specifically, they had higher rates of lifetime anxie...","downloadable_attachments":[{"id":70274429,"asset_id":53422628,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37546078,"first_name":"Michael","last_name":"Rivkin","domain_name":"independent","page_name":"MichaelRivkin","display_name":"Michael Rivkin","profile_url":"https://independent.academia.edu/MichaelRivkin?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":631,"name":"Pediatrics","url":"https://www.academia.edu/Documents/in/Pediatrics?f_ri=1819400","nofollow":false},{"id":1314,"name":"Anxiety Disorders","url":"https://www.academia.edu/Documents/in/Anxiety_Disorders?f_ri=1819400","nofollow":false},{"id":3217,"name":"Depression","url":"https://www.academia.edu/Documents/in/Depression?f_ri=1819400","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false},{"id":23868,"name":"Intellectual Disability","url":"https://www.academia.edu/Documents/in/Intellectual_Disability?f_ri=1819400"},{"id":47155,"name":"Birth Weight","url":"https://www.academia.edu/Documents/in/Birth_Weight?f_ri=1819400"},{"id":57980,"name":"Congenital Heart Defects","url":"https://www.academia.edu/Documents/in/Congenital_Heart_Defects?f_ri=1819400"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=1819400"},{"id":198747,"name":"Left Ventricular Dysfunction","url":"https://www.academia.edu/Documents/in/Left_Ventricular_Dysfunction?f_ri=1819400"},{"id":413192,"name":"Sex Factors","url":"https://www.academia.edu/Documents/in/Sex_Factors?f_ri=1819400"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=1819400"},{"id":1819399,"name":"Case Control Studies","url":"https://www.academia.edu/Documents/in/Case_Control_Studies?f_ri=1819400"},{"id":1819400,"name":"Cohort 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href="https://www.academia.edu/53304227/Maternal_macronutrient_intake_during_pregnancy_and_5_years_postpartum_and_associations_with_child_weight_status_aged_five">Maternal macronutrient intake during pregnancy and 5 years postpartum and associations with child weight status aged five</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/53304227" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cf85e3e4be0f0fe56b9277a9843e14e3" rel="nofollow" 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type="text/json">{"id":3851,"name":"Obesity","url":"https://www.academia.edu/Documents/in/Obesity?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="4583" href="https://www.academia.edu/Documents/in/Child_Development">Child Development</a>, <script data-card-contents-for-ri="4583" type="text/json">{"id":4583,"name":"Child Development","url":"https://www.academia.edu/Documents/in/Child_Development?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="29842" href="https://www.academia.edu/Documents/in/Ireland">Ireland</a><script data-card-contents-for-ri="29842" type="text/json">{"id":29842,"name":"Ireland","url":"https://www.academia.edu/Documents/in/Ireland?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=53304227]'), work: {"id":53304227,"title":"Maternal macronutrient intake during pregnancy and 5 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preschool","url":"https://www.academia.edu/Documents/in/Child_preschool?f_ri=1819400"},{"id":2845694,"name":"Adiposity","url":"https://www.academia.edu/Documents/in/Adiposity?f_ri=1819400"},{"id":3067129,"name":"postpartum period","url":"https://www.academia.edu/Documents/in/postpartum_period?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_50493508" data-work_id="50493508" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/50493508/Low_back_pain_in_a_cohort_of_622_Tunisian_schoolchildren_and_adolescents_an_epidemiological_study">Low back pain in a cohort of 622 Tunisian schoolchildren and adolescents: an epidemiological study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Low back pain (LBP) in children and adolescents was considered for many years to be rare and an indication of serious disease [1]. In the last two decades, epidemi-ological studies have shown that the prevalence of ... Ismail Bejia Nabiha... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_50493508" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Low back pain (LBP) in children and adolescents was considered for many years to be rare and an indication of serious disease [1]. In the last two decades, epidemi-ological studies have shown that the prevalence of ... Ismail Bejia Nabiha Abid Kamel Ben Salem Mondher Letaief ...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/50493508" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d5147d5388c3fd5f0ebd5ef468b018eb" rel="nofollow" data-download="{"attachment_id":68458344,"asset_id":50493508,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/68458344/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="72653385" href="https://independent.academia.edu/kamelBenSalem1">kamel Ben Salem</a><script data-card-contents-for-user="72653385" type="text/json">{"id":72653385,"first_name":"kamel","last_name":"Ben Salem","domain_name":"independent","page_name":"kamelBenSalem1","display_name":"kamel Ben Salem","profile_url":"https://independent.academia.edu/kamelBenSalem1?f_ri=1819400","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_50493508 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="50493508"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 50493508, container: ".js-paper-rank-work_50493508", }); 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In the last two decades, epidemi-ological studies have shown that the prevalence of ... Ismail Bejia Nabiha Abid Kamel Ben Salem Mondher Letaief ...","downloadable_attachments":[{"id":68458344,"asset_id":50493508,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":72653385,"first_name":"kamel","last_name":"Ben Salem","domain_name":"independent","page_name":"kamelBenSalem1","display_name":"kamel Ben Salem","profile_url":"https://independent.academia.edu/kamelBenSalem1?f_ri=1819400","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=1819400","nofollow":false},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=1819400","nofollow":false},{"id":32159,"name":"Family history","url":"https://www.academia.edu/Documents/in/Family_history?f_ri=1819400","nofollow":false},{"id":40760,"name":"Low back 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Syndrome","url":"https://www.academia.edu/Documents/in/Obstructive_Sleep_Apnea_Syndrome?f_ri=1819400"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_32287434" data-work_id="32287434" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/32287434/Clonality_investigation_of_morphologically_dysplastic_hematopoietic_cells_in_myelodysplastic_syndrome_marrows">Clonality investigation of morphologically dysplastic hematopoietic cells in myelodysplastic syndrome marrows</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" 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href="https://www.academia.edu/Documents/in/Megakaryocytes">Megakaryocytes</a><script data-card-contents-for-ri="112578" type="text/json">{"id":112578,"name":"Megakaryocytes","url":"https://www.academia.edu/Documents/in/Megakaryocytes?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=32287434]'), work: {"id":32287434,"title":"Clonality investigation of morphologically dysplastic hematopoietic cells in myelodysplastic syndrome 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href="https://www.academia.edu/2641177/A_nationwide_cohort_study_of_educational_background_and_major_causes_of_death_among_the_elderly_population_in_Japan">A nationwide cohort study of educational background and major causes of death among the elderly population in Japan</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This prospective cohort study examined the association between educational level and major causes of death in Japan.A baseline survey was conducted between 1988 and 1990 among 110,792 inhabitants of 45 areas aged 40–79 years. Follow-up... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_2641177" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This prospective cohort study examined the association between educational level and major causes of death in Japan.A baseline survey was conducted between 1988 and 1990 among 110,792 inhabitants of 45 areas aged 40–79 years. Follow-up surveys were conducted annually and causes of death were identified from death certificates. The analysis was restricted to 16,715 men and 23,284 women.During the follow-up period (377,139 person-years), 6628 deaths were recorded. Individuals with low levels of education had an increased overall risk of death [relative risk (RR) = 1.16, 95% confidence interval (CI): 1.08, 1.25, in men; RR = 1.26, 95% CI: 1.14, 1.39, in women], cancers (RR = 1.17, 95% CI: 1.04, 1.32, in men; RR = 1.10, 95% CI: 0.93, 1.30, in women), and death from external causes (RR = 1.81, 95% CI: 1.29. 2.54, in men; RR = 1.78, 95% CI: 1.18, 2.70, in women). Ischemic heart disease risk was marginally reduced in men with low levels of education (RR = 0.77, 95% CI: 0.58, 1.01).These results show that health inequalities exist in Japan, even though wealth inequalities are relatively low. Social and political initiatives will be needed to correct these inequities between different socioeconomic statuses.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/2641177" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0986c970c9b10ab0b23f1c8e01d86a00" rel="nofollow" data-download="{"attachment_id":50555297,"asset_id":2641177,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50555297/download_file?st=MTczMjc1ODMxMSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3363999" href="https://uoeh-u.academia.edu/YoshihisaFujino">Yoshihisa Fujino</a><script data-card-contents-for-user="3363999" type="text/json">{"id":3363999,"first_name":"Yoshihisa","last_name":"Fujino","domain_name":"uoeh-u","page_name":"YoshihisaFujino","display_name":"Yoshihisa Fujino","profile_url":"https://uoeh-u.academia.edu/YoshihisaFujino?f_ri=1819400","photo":"https://0.academia-photos.com/3363999/1130151/1416385/s65_yoshihisa.fujino.jpg"}</script></span></span></li><li class="js-paper-rank-work_2641177 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="2641177"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 2641177, container: ".js-paper-rank-work_2641177", }); 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$(".js-view-count[data-work-id=2641177]").text(description); $(".js-view-count-work_2641177").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_2641177").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="2641177"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">24</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6021" href="https://www.academia.edu/Documents/in/Cancer">Cancer</a>, <script data-card-contents-for-ri="6021" type="text/json">{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="13084" href="https://www.academia.edu/Documents/in/Preventive_medicine">Preventive medicine</a>, <script data-card-contents-for-ri="13084" type="text/json">{"id":13084,"name":"Preventive medicine","url":"https://www.academia.edu/Documents/in/Preventive_medicine?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="13734" href="https://www.academia.edu/Documents/in/Communicable_Diseases">Communicable Diseases</a>, <script data-card-contents-for-ri="13734" type="text/json">{"id":13734,"name":"Communicable Diseases","url":"https://www.academia.edu/Documents/in/Communicable_Diseases?f_ri=1819400","nofollow":false}</script><a class="InlineList-item-text" data-has-card-for-ri="17158" href="https://www.academia.edu/Documents/in/Japan">Japan</a><script data-card-contents-for-ri="17158" type="text/json">{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=1819400","nofollow":false}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=2641177]'), work: {"id":2641177,"title":"A nationwide cohort study of educational background and major causes of death among the elderly population in Japan","created_at":"2013-02-24T13:07:11.984-08:00","url":"https://www.academia.edu/2641177/A_nationwide_cohort_study_of_educational_background_and_major_causes_of_death_among_the_elderly_population_in_Japan?f_ri=1819400","dom_id":"work_2641177","summary":"This prospective cohort study examined the association between educational level and major causes of death in Japan.A baseline survey was conducted between 1988 and 1990 among 110,792 inhabitants of 45 areas aged 40–79 years. Follow-up surveys were conducted annually and causes of death were identified from death certificates. The analysis was restricted to 16,715 men and 23,284 women.During the follow-up period (377,139 person-years), 6628 deaths were recorded. Individuals with low levels of education had an increased overall risk of death [relative risk (RR) = 1.16, 95% confidence interval (CI): 1.08, 1.25, in men; RR = 1.26, 95% CI: 1.14, 1.39, in women], cancers (RR = 1.17, 95% CI: 1.04, 1.32, in men; RR = 1.10, 95% CI: 0.93, 1.30, in women), and death from external causes (RR = 1.81, 95% CI: 1.29. 2.54, in men; RR = 1.78, 95% CI: 1.18, 2.70, in women). Ischemic heart disease risk was marginally reduced in men with low levels of education (RR = 0.77, 95% CI: 0.58, 1.01).These results show that health inequalities exist in Japan, even though wealth inequalities are relatively low. Social and political initiatives will be needed to correct these inequities between different socioeconomic statuses.","downloadable_attachments":[{"id":50555297,"asset_id":2641177,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3363999,"first_name":"Yoshihisa","last_name":"Fujino","domain_name":"uoeh-u","page_name":"YoshihisaFujino","display_name":"Yoshihisa Fujino","profile_url":"https://uoeh-u.academia.edu/YoshihisaFujino?f_ri=1819400","photo":"https://0.academia-photos.com/3363999/1130151/1416385/s65_yoshihisa.fujino.jpg"}],"research_interests":[{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=1819400","nofollow":false},{"id":13084,"name":"Preventive medicine","url":"https://www.academia.edu/Documents/in/Preventive_medicine?f_ri=1819400","nofollow":false},{"id":13734,"name":"Communicable 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