Alzheimer's Society Continue £5m Blood Biomarker Challenge for Dementia Blood Tests on NHS

<!doctype html><html lang="en"><head> <meta charset="utf-8"> <title>Alzheimer's Society Continue £5m Blood Biomarker Challenge for Dementia Blood Tests on NHS</title> <link rel="shortcut icon" href="https://oxfordglobal.com/hubfs/OXFORD_GLOBAL-LOGO_SYMBOL.jpg"> <meta name="description" content="The Blood Biomarker Challenge hopes to ‘revolutionize dementia diagnosis in the UK’ through a collaborative pilot of blood tests in the NHS."> <meta name="viewport" content="width=device-width, initial-scale=1"> <meta property="og:description" content="The Blood Biomarker Challenge hopes to ‘revolutionize dementia diagnosis in the UK’ through a collaborative pilot of blood tests in the NHS."> <meta property="og:title" content="Alzheimer's Society Continue £5m Blood Biomarker Challenge for Dementia Blood Tests on NHS"> <meta name="twitter:description" content="The Blood Biomarker Challenge hopes to ‘revolutionize dementia diagnosis in the UK’ through a collaborative pilot of blood tests in the NHS."> <meta name="twitter:title" content="Alzheimer's Society Continue £5m Blood Biomarker Challenge for Dementia Blood Tests on NHS"> <style> a.cta_button{-moz-box-sizing:content-box !important;-webkit-box-sizing:content-box !important;box-sizing:content-box !important;vertical-align:middle}.hs-breadcrumb-menu{list-style-type:none;margin:0px 0px 0px 0px;padding:0px 0px 0px 0px}.hs-breadcrumb-menu-item{float:left;padding:10px 0px 10px 10px}.hs-breadcrumb-menu-divider:before{content:'›';padding-left:10px}.hs-featured-image-link{border:0}.hs-featured-image{float:right;margin:0 0 20px 20px;max-width:50%}@media (max-width: 568px){.hs-featured-image{float:none;margin:0;width:100%;max-width:100%}}.hs-screen-reader-text{clip:rect(1px, 1px, 1px, 1px);height:1px;overflow:hidden;position:absolute !important;width:1px} </style> <link rel="stylesheet" href="https://oxfordglobal.com/hs-fs/hub/8696823/hub_generated/template_assets/135726131582/1732113079147/git/og-stage/css/main.min.css"> <link rel="stylesheet" href="https://cdn.oxfordglobal.com/fontawesome/6.5.1/css/fontawesome.min.css"> <link rel="stylesheet" href="https://cdn.oxfordglobal.com/fontawesome/6.5.1/css/brands.min.css"> <link rel="stylesheet" href="https://cdn.oxfordglobal.com/fontawesome/6.5.1/css/solid.min.css">  <style id="hs_editor_style" type="text/css"> #hs_cos_wrapper_module_17019620504109 { display: block !important; margin-bottom: 0px !important } </style>  <script> var _hsp = window._hsp = window._hsp || []; window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} var useGoogleConsentModeV2 = true; var waitForUpdateMillis = 1000; if (!window._hsGoogleConsentRunOnce) { window._hsGoogleConsentRunOnce = true; gtag('consent', 'default', { 'ad_storage': 'denied', 'analytics_storage': 'denied', 'ad_user_data': 'denied', 'ad_personalization': 'denied', 'wait_for_update': waitForUpdateMillis }); if (useGoogleConsentModeV2) { _hsp.push(['useGoogleConsentModeV2']) } else { _hsp.push(['addPrivacyConsentListener', function(consent){ var hasAnalyticsConsent = consent && (consent.allowed || (consent.categories && consent.categories.analytics)); var hasAdsConsent = consent && (consent.allowed || (consent.categories && consent.categories.advertisement)); gtag('consent', 'update', { 'ad_storage': hasAdsConsent ? 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id="main-content"> <div class="resource-single"> <div class="header bg-primary-light"> <div class="container-wrapper"> <div class="wide-container header-container"> <div class="header-content flex-1"> <div class="heading-smallcaps"> Liquid Biopsies | Industry Spotlights & Insight Articles </div> <h1 class="heading"> Alzheimer's Society Continue £5m Blood Biomarker Challenge for Dementia Blood Tests on NHS </h1> <div class="byline"> Edited by Tom Cohen | 14 November 2024 </div> <div class="abstract"> The Blood Biomarker Challenge hopes to ‘revolutionize dementia diagnosis in the UK’ through a collaborative pilot of blood tests in the NHS. </div> </div> <div class="header-graphic flex-1"> <img src="https://oxfordglobal.com/hubfs/Website/Images/Resources/Precision%20Medicine/Alzheimers%20Society%20Continue%20%C2%A35m%20Blood%20Biomarker%20Challenge%20for%20Dementia%20Blood%20Tests%20on%20NHS.jpg" class="header-graphic-image"> </div> </div> </div> </div> <div class="container-wrapper"> <div class="wide-container"> <div class="content"> <div class="content-body text-gap"> <p>The Alzheimer’s Society has announced that it will continue its work on the Blood Biomarker Challenge: a £5 million award to “revolutionise dementia diagnosis in the UK.”</p> <p>Together with a collaborative team, the Society will join Alzheimer’s Research UK and the National Institute for Health and Care Research (NIHR) to pilot the use of dementia blood tests in the NHS.</p> <ul> <li><a href="https://oxfordglobal.com/precision-medicine/resources/feinstein-institutes-links-blood-biomarkers-to-psychosis-in-alzheimers-patients" rel="noopener" target="_blank">Feinstein Institutes Links Blood Biomarkers to Psychosis in Alzheimer's Patients</a></li> <li><a href="https://oxfordglobal.com/precision-medicine/resources/syn-saa-biomarker-highly-correlated-with-dementia-with-lewy-bodies" rel="noopener" target="_blank">αSyn-SAA Biomarker Highly Correlated with Dementia with Lewy Bodies</a></li> <li><a href="https://oxfordglobal.com/precision-medicine/resources/who-publishes-preferred-product-characteristics-for-alzheimers-blood-tests" rel="noopener" target="_blank">WHO Publishes Preferred Product Characteristics for Alzheimer’s Blood Tests</a></li> <li><a href="https://oxfordglobal.com/precision-medicine/resources/early-diagnostic-blood-biomarker-for-dementia-identified-using-proteomics" rel="noopener" target="_blank">Early Diagnostic Blood Biomarker for Dementia Identified Using Proteomics</a></li> </ul> <p>Liquid biopsies for diseases which cause dementia have emerged as a powerful diagnostic tool for such diseases. They fill a substantial unmet need as it’s estimated that a third of people living with dementia are currently undiagnosed.</p> <p>Fiona Carragher, Director of Research and Influencing at Alzheimer’s Society, said: “New drugs targeting early-stage Alzheimer’s disease are just around the corner. But without a diagnosis, people simply won’t be able to access them if they are approved.”</p> <p>However, there is currently a lack of research to support the full rollout of blood tests for Alzheimer’s in the NHS. The Blood Biomarker Challenge aims to demonstrate the accuracy of blood tests for dementia-causing diseases in UK patients with suspected dementia. It also seeks to ensure that these tests integrate well with the NHS Healthcare system.</p> <p>Susan Kohlhaas, Executive Director of Research and Partnerships at Alzheimer’s Research UK, said: “We’re sitting on the cusp of a new era of dementia treatments.”</p> <p>"Doctors are likely going to see more people coming forward for a diagnosis. But the NHS doesn’t possess the required levels of diagnostic infrastructure to cope with this growing demand."</p> <p>Vanessa Raymont, an Associate Professor at the University of Oxford will lead the team named READ-OUT (REAl world Dementia OUTcomes) to carry out the research. The team will be comprised of Dementias Platform UK researchers from the Universities of Oxford and Cambridge. They’ll test multiple existing and novel blood tests for a range of dementia types in the hopes of validating the diagnostic tool</p> <p>A second team, ADAPT (Alzheimer's disease Diagnosis and Plasma pTau217), will focus on the protein pTau217 which has proved to be the most promising blood-based biomarker for Alzheimer’s. ADAPT will be led by Professor of Neurology Jonathan Schott and Senior Clinical Research Fellow Ashvini Keshavan at University College London.</p> <p>Blood tests for Alzheimer’s detect two proteins in the blood: amyloid and tau proteins. People with Alzheimer’s disease have these proteins build up in their brain which then are cleared through cerebrospinal fluid. Amyloid and tau then end up in the blood stream, which researchers are attempting to exploit for the detection of Alzheimer's.</p> <p>Some researchers have suggested that the blood-brain barrier becomes leaky in Alzheimer’s disease patients, which is how those proteins find themselves in the blood. Another theory suggests that amyloid and tau are produced in other parts of the body which naturally get excreted into the blood.</p> <p>Carragher added: "This could absolutely revolutionise the way dementia is diagnosed."</p> <p>With the promising advancements in liquid biopsy technologies and the dedicated efforts of leading researchers, the future holds great potential for early and accurate diagnosis of dementia. These breakthroughs will pave the way for timely interventions and improved outcomes for millions of patients worldwide.</p> <div class="content-body-footer"> </div> </div> <div class="content-sidebar"> <div class="related-event"> <h3 class="center">Related Events</h3> For more on this topic, you may be interested in our upcoming <a href="/precision-medicine/events/biomarkers-precision-medicine-2025">Biomarkers & Precision Medicine 2025</a> </div> <div class="related-articles"> <h3 class="center">Related Resources</h3> <div class="article"> <a href="/precision-medicine/resources/syn-saa-biomarker-highly-correlated-with-dementia-with-lewy-bodies"> <div class="cover-graphic"> <img src="https://oxfordglobal.com/hubfs/Website/Images/Resources/Precision%20Medicine/640px-Lewy_bodies_(alpha_synuclein_inclusions)_1.jpg" class="cover-graphic-image"> </div> </a><div class="content"><a href="/precision-medicine/resources/syn-saa-biomarker-highly-correlated-with-dementia-with-lewy-bodies"> <h4> αSyn-SAA Biomarker Highly Correlated with Dementia with Lewy Bodies </h4> <div class="abstract"> The study says that it provides Class III evidence for the assay distinguishing between DLB-positive patients and healthy controls. </div> <div class="read-more"> <a href="/precision-medicine/resources/syn-saa-biomarker-highly-correlated-with-dementia-with-lewy-bodies" class="read-more-link">Read More</a> </div></a> </div> </div> <div class="article"> <a href="/precision-medicine/resources/fully-automated-diagnostic-test-for-kidney-graft-rejection"> <div class="cover-graphic"> <img src="https://oxfordglobal.com/hubfs/Website/Documents/Whitepaper%20Upload%2022.10.24/CaseStudy_Fully%20automated%20diagnostic%20test%20for%20kidney%20graft%20rejection.jpg" class="cover-graphic-image"> </div> </a><div class="content"><a href="/precision-medicine/resources/fully-automated-diagnostic-test-for-kidney-graft-rejection"> <h4> Fully automated diagnostic test for kidney graft rejection </h4> <div class="abstract"> </div> <div class="read-more"> <a href="/precision-medicine/resources/fully-automated-diagnostic-test-for-kidney-graft-rejection" class="read-more-link">Read More</a> </div></a> </div> </div> </div> <div class="related-online-activities"> <h3 class="center">Related Online Activities</h3> Join the conversation with our upcoming Monthly Science Exchanges and Webinars: <div class="online-activity"> <div class="heading-smallcaps"> 13/01/25 </div> <a href="/precision-medicine/online#Regulatory%20developments%20for%20biomarker%20research">Regulatory developments for biomarker research</a> </div> </div> </div> </div> </div> </div> </div> <div class="newsletter-cta"> <h2 class="heading">Subscribe to our newsletter</h2> <div class="message"> Sign up for our monthly Newsletter to keep up with all things Precision Medicine </div> <div class="button-wrapper"> <a href="#" class="button hs-cta-trigger-button hs-cta-trigger-button-177053686110">Newsletter Sign-Up</a> </div> </div> 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Alzheimer's Society Continue £5m Blood Biomarker Challenge for Dementia Blood Tests on NHS