Stem Cell Proteins and Cultures for Research

<!DOCTYPE html> <html lang="en" dir="ltr" prefix="og: https://ogp.me/ns#"> <head> <meta charset="utf-8" /> <noscript><style>form.antibot * :not(.antibot-message) { display: none !important; }</style> </noscript><meta name="applicable-device" content="pc,mobile" /> <meta name="description" content="Explore a wide variety of stem cell proteins from R&D Systems. Our cytokines include proteins ranging from Activin A and Wnt-3a to Noggin." /> <link rel="canonical" href="https://www.bio-techne.com/reagents/proteins/stem-cell-proteins" /> <meta property="og:site_name" content="Bio-Techne" /> <meta property="og:type" content="website" /> <meta property="og:url" content="https://www.bio-techne.com/reagents/proteins/stem-cell-proteins" /> <meta property="og:image" content="https://resources.bio-techne.com/bio-techne-assets/images/brands/bio-techne-og.png" /> <meta name="published-date" content="1624910957" /> <meta name="revision-date" content="1724873840" /> <meta name="Generator" content="Drupal 10 (https://www.drupal.org)" /> <meta name="MobileOptimized" content="width" /> <meta name="HandheldFriendly" content="true" /> <meta name="viewport" content="width=device-width, initial-scale=1.0" /> <script type="application/ld+json">{ "@context": "https://schema.org", "@graph": [ { "@type": "WebPage", "@id": "https://www.bio-techne.com/reagents/proteins/stem-cell-proteins", "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "Home", "item": "https://www.bio-techne.com/" }, { "@type": "ListItem", "position": 2, "name": "Bio-Techne Reagents", "item": "https://www.bio-techne.com/reagents" }, { "@type": "ListItem", "position": 3, "name": "Proteins", "item": "https://www.bio-techne.com/reagents/proteins" } ] } } ] }</script> <meta http-equiv="x-dns-prefetch-control" content="on" /> <meta http-equiv="x-ua-compatible" content="ie=edge" /> <link rel="alternate" hreflang="en" href="https://www.bio-techne.com/reagents/proteins/stem-cell-proteins" /> <link rel="alternate" hreflang="zh-hans" href="https://www.bio-techne.com/cn/reagents/proteins/stem-cell-proteins" /> <link rel="icon" href="/themes/custom/bio_techne_global/favicon.ico" type="image/vnd.microsoft.icon" /> <link rel="preconnect" href="https://resources.bio-techne.com" /> <link rel="preconnect" href="https://resources.tocris.com" /> <link rel="preconnect" href="https://i.icomoon.io" /> <link rel="preconnect" href="https://cdn.icomoon.io" /> <link rel="dns-prefetch" href="https://connect.facebook.net" /> <link rel="dns-prefetch" href="https://resources.bio-techne.com" /> <link rel="dns-prefetch" href="https://snap.licdn.com" /> <link rel="dns-prefetch" href="https://www.google-analytics.com" /> <link rel="dns-prefetch" href="https://munchkin.marketo.net" /> <link rel="dns-prefetch" href="https://resources.tocris.com" /> <link rel="dns-prefetch" href="https://i.icomoon.io" /> <link rel="dns-prefetch" href="https://cdn.icomoon.io" /> <title>Stem Cell Proteins and Cultures for Research | Bio-Techne</title> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_ZxgPvtjfU58dVOS4x7hBdmXFv-da3Cr5fEZJ4OaYVB4.css?delta=0&language=en&theme=bio_techne_global&include=eJxNzmFuwyAMBeALQTiSZcBNvDiYGuiUnX5J06399aTP0vMzalVL4wdBxygEN5ZOFuzf_dNd21unLURs5CIrdEpLIZhFI0q4wre-C5fZfd0H2Q6DoVUu5eh7pUuqKxMU7XzjhJ21hMv8p_komlZX0XA2rEsL2UZFmd4yjVJHFG4LZSe46-gQB0s-vvVvTSrQKJ1lLgr-7EEU8zmumuaR-nFFS0u4AiKe47aNLBHcB6dV7az6M_-26TnuF94DfJ4" /> <link rel="stylesheet" media="all" href="/sites/default/files/css/css_d9gn2GRzRb_AMxXfgjVqY5zLMXvuwkXc1qKvoeAAIxE.css?delta=1&language=en&theme=bio_techne_global&include=eJxNzmFuwyAMBeALQTiSZcBNvDiYGuiUnX5J06399aTP0vMzalVL4wdBxygEN5ZOFuzf_dNd21unLURs5CIrdEpLIZhFI0q4wre-C5fZfd0H2Q6DoVUu5eh7pUuqKxMU7XzjhJ21hMv8p_komlZX0XA2rEsL2UZFmd4yjVJHFG4LZSe46-gQB0s-vvVvTSrQKJ1lLgr-7EEU8zmumuaR-nFFS0u4AiKe47aNLBHcB6dV7az6M_-26TnuF94DfJ4" /> <script type="application/json" data-drupal-selector="drupal-settings-json">{"path":{"baseUrl":"\/","pathPrefix":"","currentPath":"node\/1726","currentPathIsAdmin":false,"isFront":false,"currentLanguage":"en"},"pluralDelimiter":"\u0003","suppressDeprecationErrors":true,"gtm":{"tagId":null,"settings":{"data_layer":"dataLayer","include_environment":false},"tagIds":["GTM-N2MWQDR"]},"gtag":{"tagId":"","consentMode":false,"otherIds":[],"events":[],"additionalConfigInfo":[]},"ajaxPageState":{"libraries":"eJxtk22W2yAMRTcEYUkcgRVbDUZUyMl4Vl_5I8m0zR-QLg_zEHIijop5qhjHwglKSMzaVaDFPFSX_ls_Jt91LVTHDwLKPDN_2lrge_WFYfiwNuNA4L3gzIr-TgPypjpFhe4YYcSq4QX9Bv0OLUwCsrq0HRH28Yxzgd4LdT3z4_g9bFzWK5XyTIVn6nhmAtczemBqFjLPgpCn2OgLSxhAocCK4tvSJxSXNGKdoGYcIloJZpSMIal_Uv-ivpPiw67o8W7uu3vJX4qjKq-F-HuhfGMZUN6aN7uYvXwzNd8IY2WlK2VQ4hoO5n8yf6hfNwgJJ7gTS3do1VLKsYFOcekoEXLmxTyGM7AX0kWqb1Z4K3u9uZF5LBgVxjDa8G9-gV_w9TecHVVFqbsbKPT9tGrfl9V3LJj1cOlbgYwTF7ulM7e8aEwLbWnQB2cusZvYtrsGAqP17dTDIEuDcnmTy1LbkqwNJhycPfSwZLWNIHkKxxQTiBPsjWvfmk0hmV9rDzMa3tzv3PW1K84hgfXLXiaqV5b5uMcG_A_w_Ff-ACiBVz0","theme":"bio_techne_global","theme_token":null},"ajaxTrustedUrl":[],"dataLayer":{"defaultLang":"en","languages":{"en":{"id":"en","name":"English","direction":"ltr","weight":0},"zh-hans":{"id":"zh-hans","name":"Chinese, Simplified","direction":"ltr","weight":1},"ja":{"id":"ja","name":"Japanese","direction":"ltr","weight":2}}},"internationalization":{"origin":{"id":"us","label":"US","country_name":"United States","alternate_spellings":"US USA","country_enabled":true,"country_encased":false,"commerce_enabled":true,"credit_cards_enabled":true,"region":"North America","currency":"USD","localities":"[{\u0022text\u0022:\u0022Delaware\u0022,\u0022value\u0022:\u0022DE\u0022},{\u0022text\u0022:\u0022Hawaii\u0022,\u0022value\u0022:\u0022HI\u0022},{\u0022text\u0022:\u0022Puerto Rico\u0022,\u0022value\u0022:\u0022PR\u0022},{\u0022text\u0022:\u0022Texas\u0022,\u0022value\u0022:\u0022TX\u0022},{\u0022text\u0022:\u0022Palau\u0022,\u0022value\u0022:\u0022PW\u0022},{\u0022text\u0022:\u0022Massachusetts\u0022,\u0022value\u0022:\u0022MA\u0022},{\u0022text\u0022:\u0022Maryland\u0022,\u0022value\u0022:\u0022MD\u0022},{\u0022text\u0022:\u0022Maine\u0022,\u0022value\u0022:\u0022ME\u0022},{\u0022text\u0022:\u0022Iowa\u0022,\u0022value\u0022:\u0022IA\u0022},{\u0022text\u0022:\u0022Marshall Islands\u0022,\u0022value\u0022:\u0022MH\u0022},{\u0022text\u0022:\u0022Idaho\u0022,\u0022value\u0022:\u0022ID\u0022},{\u0022text\u0022:\u0022Michigan\u0022,\u0022value\u0022:\u0022MI\u0022},{\u0022text\u0022:\u0022Utah\u0022,\u0022value\u0022:\u0022UT\u0022},{\u0022text\u0022:\u0022Armed Forces (AA)\u0022,\u0022value\u0022:\u0022AA\u0022},{\u0022text\u0022:\u0022Minnesota\u0022,\u0022value\u0022:\u0022MN\u0022},{\u0022text\u0022:\u0022Missouri\u0022,\u0022value\u0022:\u0022MO\u0022},{\u0022text\u0022:\u0022Northern Mariana Islands\u0022,\u0022value\u0022:\u0022MP\u0022},{\u0022text\u0022:\u0022Illinois\u0022,\u0022value\u0022:\u0022IL\u0022},{\u0022text\u0022:\u0022Armed Forces (AE)\u0022,\u0022value\u0022:\u0022AE\u0022},{\u0022text\u0022:\u0022Indiana\u0022,\u0022value\u0022:\u0022IN\u0022},{\u0022text\u0022:\u0022Mississippi\u0022,\u0022value\u0022:\u0022MS\u0022},{\u0022text\u0022:\u0022Montana\u0022,\u0022value\u0022:\u0022MT\u0022},{\u0022text\u0022:\u0022Alaska\u0022,\u0022value\u0022:\u0022AK\u0022},{\u0022text\u0022:\u0022Virginia\u0022,\u0022value\u0022:\u0022VA\u0022},{\u0022text\u0022:\u0022Alabama\u0022,\u0022value\u0022:\u0022AL\u0022},{\u0022text\u0022:\u0022Armed Forces (AP)\u0022,\u0022value\u0022:\u0022AP\u0022},{\u0022text\u0022:\u0022Arkansas\u0022,\u0022value\u0022:\u0022AR\u0022},{\u0022text\u0022:\u0022American Samoa\u0022,\u0022value\u0022:\u0022AS\u0022},{\u0022text\u0022:\u0022Virgin Islands\u0022,\u0022value\u0022:\u0022VI\u0022},{\u0022text\u0022:\u0022North Carolina\u0022,\u0022value\u0022:\u0022NC\u0022},{\u0022text\u0022:\u0022North Dakota\u0022,\u0022value\u0022:\u0022ND\u0022},{\u0022text\u0022:\u0022Rhode Island\u0022,\u0022value\u0022:\u0022RI\u0022},{\u0022text\u0022:\u0022Nebraska\u0022,\u0022value\u0022:\u0022NE\u0022},{\u0022text\u0022:\u0022Arizona\u0022,\u0022value\u0022:\u0022AZ\u0022},{\u0022text\u0022:\u0022New Hampshire\u0022,\u0022value\u0022:\u0022NH\u0022},{\u0022text\u0022:\u0022New Jersey\u0022,\u0022value\u0022:\u0022NJ\u0022},{\u0022text\u0022:\u0022Vermont\u0022,\u0022value\u0022:\u0022VT\u0022},{\u0022text\u0022:\u0022New Mexico\u0022,\u0022value\u0022:\u0022NM\u0022},{\u0022text\u0022:\u0022Florida\u0022,\u0022value\u0022:\u0022FL\u0022},{\u0022text\u0022:\u0022Micronesia\u0022,\u0022value\u0022:\u0022FM\u0022},{\u0022text\u0022:\u0022Nevada\u0022,\u0022value\u0022:\u0022NV\u0022},{\u0022text\u0022:\u0022Washington\u0022,\u0022value\u0022:\u0022WA\u0022},{\u0022text\u0022:\u0022New York\u0022,\u0022value\u0022:\u0022NY\u0022},{\u0022text\u0022:\u0022South Carolina\u0022,\u0022value\u0022:\u0022SC\u0022},{\u0022text\u0022:\u0022South Dakota\u0022,\u0022value\u0022:\u0022SD\u0022},{\u0022text\u0022:\u0022Wisconsin\u0022,\u0022value\u0022:\u0022WI\u0022},{\u0022text\u0022:\u0022Ohio\u0022,\u0022value\u0022:\u0022OH\u0022},{\u0022text\u0022:\u0022Georgia\u0022,\u0022value\u0022:\u0022GA\u0022},{\u0022text\u0022:\u0022Oklahoma\u0022,\u0022value\u0022:\u0022OK\u0022},{\u0022text\u0022:\u0022California\u0022,\u0022value\u0022:\u0022CA\u0022},{\u0022text\u0022:\u0022West Virginia\u0022,\u0022value\u0022:\u0022WV\u0022},{\u0022text\u0022:\u0022Wyoming\u0022,\u0022value\u0022:\u0022WY\u0022},{\u0022text\u0022:\u0022Oregon\u0022,\u0022value\u0022:\u0022OR\u0022},{\u0022text\u0022:\u0022Kansas\u0022,\u0022value\u0022:\u0022KS\u0022},{\u0022text\u0022:\u0022Colorado\u0022,\u0022value\u0022:\u0022CO\u0022},{\u0022text\u0022:\u0022Kentucky\u0022,\u0022value\u0022:\u0022KY\u0022},{\u0022text\u0022:\u0022Guam\u0022,\u0022value\u0022:\u0022GU\u0022},{\u0022text\u0022:\u0022Pennsylvania\u0022,\u0022value\u0022:\u0022PA\u0022},{\u0022text\u0022:\u0022Connecticut\u0022,\u0022value\u0022:\u0022CT\u0022},{\u0022text\u0022:\u0022Louisiana\u0022,\u0022value\u0022:\u0022LA\u0022},{\u0022text\u0022:\u0022Tennessee\u0022,\u0022value\u0022:\u0022TN\u0022},{\u0022text\u0022:\u0022District of Columbia\u0022,\u0022value\u0022:\u0022DC\u0022}]","phone_pattern":"","country_shipping":"45","shipping_delay":0,"country_contact_message":"","product_block_message":"","default_language_setting":"en","default_contact_email":""},"languagePrefix":"\/"},"bloomreach_pixel":{"br_info":{"acct_id":"6368","domain_key":"biotechne"},"page_info":{"ptype":"content"},"order_info":{"order_id":""},"user_info":{"uid":0},"searchbar":{"enabled":"1","form":".product-search-form","input":"#edit-keywords"},"atc":{"enabled":"1","form":".add-to-cart-block"}},"blazy":{"loadInvisible":false,"offset":100,"saveViewportOffsetDelay":50,"validateDelay":25,"loader":true,"unblazy":false,"visibleClass":false},"blazyIo":{"disconnect":false,"rootMargin":"0px","threshold":[0,0.25,0.5,0.75,1]},"user":{"uid":0,"permissionsHash":"085655eba91c5b5dd7808236555504ceb824f9fddd71e3c0265b4003df711142"}}</script> <script src="/sites/default/files/js/js_VXwrJf_GoEAY9I4SWeDh30VrU0-JgQhDzf_eoQcyzA4.js?scope=header&delta=0&language=en&theme=bio_techne_global&include=eJxtUltywzAIvJCpjqRBMrFpsfAgnMQ5fRU_Mn3kR1oWZtGCEqtTHgtF4StFHKh4SCcJTxI2ssFkaGvXo6PgShYSjXhltdqRYHXOcUYf41LJIuasS_EaDgBGvliBuYk1qfLVtSbxaD2IJpSQVL264RxzX97k9wuqr01g6AbVQSg6DmHw6XeIw9_4Az_x3iWPVEYsmfpIWaeJLFNIDicLLxYqO924J6Br81-7V_mrYn9QS-gXUyzqfOGMzlrCzsFPDpJobr5FdTLCPMaZ7yThNVCYlzqStQp8rGE7DyyK_QFnlfXCIkeY2-SrcPUzbTpxpSMyvBzoRml-M9KJekZoy5naxuHa3GrXJPole6yElsewXzGhdVycrGxmUPhxOm3rtRUqCWXfTcIsmGlU6Z92_nV9vgg2T9tf4XJRm3a1JwE_iHPb37d_CXQ"></script> <script src="/modules/contrib/google_tag/js/gtm.js?snbwxk"></script> <script src="/modules/contrib/google_tag/js/gtag.js?snbwxk"></script> <script src="/sites/default/files/js/js_noO6VL3JUON9fTBkbqcAjEkLsfpTqx94dWIfXpNxuMg.js?scope=header&delta=3&language=en&theme=bio_techne_global&include=eJxtUltywzAIvJCpjqRBMrFpsfAgnMQ5fRU_Mn3kR1oWZtGCEqtTHgtF4StFHKh4SCcJTxI2ssFkaGvXo6PgShYSjXhltdqRYHXOcUYf41LJIuasS_EaDgBGvliBuYk1qfLVtSbxaD2IJpSQVL264RxzX97k9wuqr01g6AbVQSg6DmHw6XeIw9_4Az_x3iWPVEYsmfpIWaeJLFNIDicLLxYqO924J6Br81-7V_mrYn9QS-gXUyzqfOGMzlrCzsFPDpJobr5FdTLCPMaZ7yThNVCYlzqStQp8rGE7DyyK_QFnlfXCIkeY2-SrcPUzbTpxpSMyvBzoRml-M9KJekZoy5naxuHa3GrXJPole6yElsewXzGhdVycrGxmUPhxOm3rtRUqCWXfTcIsmGlU6Z92_nV9vgg2T9tf4XJRm3a1JwE_iHPb37d_CXQ"></script> </head> <body class="node-1726 node-type-hero-page"> <a href="#main-content" class="visually-hidden focusable"> Skip to main content </a> <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-N2MWQDR" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div id="page-wrapper"> <div id="page"> <header id="header" class="header" role="banner" aria-label="Site header"> <div class="section layout-container clearfix"> <section id="site-header__top"> <div class="container-fluid container-wide"> <div class="row m___navigation-utility-top"> <div class="col-xl-2 col-lg-12 text-xl-left text-lg-center"> <div id="site-header__logo" class="valign d-none d-lg-block mb-md-3"> <div> <div id="block-sitebranding" class="site-branding system_branding_block"> <a href="/" title="Home" rel="home" class="site-branding__logo"> <img width="160" height="28" src="/themes/custom/bio_techne_global/logo.svg" alt="Home" /> </a> </div> </div> </div> </div> <div class="col d-none d-xl-block text-lg-left text-md-center"> <div class="utility-bar-tagline rotating-text position-absolute"> <p class="ml-xl-4 bt-px_groteskbold text-white mb-0"> Global Developer, Manufacturer, and Supplier of High-Quality<br/> Reagents, Analytical Instruments, and Precision Diagnostics. </p> </div> <div class="utility-bar-brands rotating-text position-absolute ml-xl-4 text-white mb-0"> <div class="row"> <div class="col-2"> <div class="bt-px_groteskbold valign utility-bar-includes">INCLUDES</div> </div> <div class="col-lg-10 col-md-auto bt-inter"> <span class="mr-3">R&D Systems<sup>TM</sup></span> <span class="mr-3">Novus Biologicals<sup>TM</sup></span> <span class="mr-3">Tocris Bioscience<sup>TM</sup></span><br/> <span class="mr-3">ProteinSimple<sup>TM</sup></span> <span class="mr-3">ACD<sup>TM</sup></span> <span class="mr-3">ExosomeDx<sup>TM</sup></span> <span class="mr-3">Asuragen<sup style="font-size:11px;">®</sup></span> <span>Lunaphore<sup>TM</sup></span> </div> </div> </div> </div> <div class="col-xl-auto col-lg-12"> <div class="row"> <div class="col text-xl-left text-center"> </div> </div> <div class="row"> <div class="col text-xl-left text-center"> <nav id="site-header-top__left m___navigation-language"> <div> <div id="block-i18ncountryselect" class="i18n_country_select"> <div id="country-select-block-placeholder"> <div id="country-select-block-spinner" class="spinner-border spinner-border-sm mt-3 ml-3" role="status"> <span class="sr-only">Loading...</span> </div> </div> </div> </div> </nav> </div> </div> </div> </div> </div> </section> <div id="hero-banner" class="position-relative"> <div id="header-wrapper" class="position-absolute w-100"> <section id="site-header__middle"> <div class="container-fluid container-wide"> <div class="row search-row"> <div id="hamburger-col" class="col-3 col-sm-3 col-md-2 d-block d-lg-none"> <button class="navbar-toggler collapsed" type="button" data-toggle="collapse" data-target="#navbarSupportedContent" aria-controls="navbarSupportedContent" aria-expanded="false" aria-label="Toggle navigation"> <span class="icon-bar top-bar"></span> <span class="icon-bar middle-bar"></span> <span class="icon-bar bottom-bar"></span> </button> </div> <div class="col-6 col-sm-6 col-md-8 d-block d-lg-none text-center"> <div id="site-header__logo" class="vertical-align mb-3"> <div> <div id="block-sitebranding" class="site-branding system_branding_block"> <a href="/" title="Home" rel="home" class="site-branding__logo"> <img width="160" height="28" src="/themes/custom/bio_techne_global/logo.svg" alt="Home" /> </a> </div> </div> </div> </div> <div id="tools-col" class="col-3 col-md-12 col-lg-auto order-sm-1 order-md-12 order-lg-12"> <div id="site-header__tools" class="vertical-align"> <div class="row"> <div class="col-md-12"> <div class="d-flex justify-content-end justify-content-md-center justify-content-lg-end"> <div class="text-right order-3 user_cart_information_block" id="block-biotechnecartinformation"> <a class="btn-primary position-relative" href="/cart/view-cart"> <span class="icon icon-bt-icon-cart"></span> <span class="cart-count-wrap"> </span> <span class="cart-text">Cart</span> </a> </div> <div class="mr-3 d-none d-md-block order-2 block-quickorderblock quick_order_block" id="block-quickorderblock"> <div class="quick-order-block js-quickorder"> <div class="quick-order-block__link js-quickorder-link d-none d-md-block rounded-top position-relative"> <span class="js-link-text quick-order-block__link-text"> <a class="btn-primary" href="/commerce/quickorder"><span class="icon icon-bt-icon-quick-order"></span>Quick Order</a> </span> </div> </div> </div> <div class="mr-3 order-1 user_account_information_block" id="block-biotechneuserinformation"> <a class="btn btn-primary" rel="nofollow" href="/account/login" role="button"> <span class="icon icon-bt-icon-user"></span> Sign In / Register </a> </div> </div> </div> </div> </div> </div> <div class="col order-sm-12 order-md-1 order-lg-1"> <div id="site-header__search">  <section role="search" class="vertical-align"> <div> <div class="block-product-search-form-block product_search_form_block" id="block-product-search-form-block"> <div class="row"> <div class="col-sm-12 search-bar mb-md-4"> <form class="product-search-form" action="/search" method="get" id="product-search-form" accept-charset="UTF-8" data-date="2024-11-21 07:11:32"> <div class="container-inline input-group" id="edit-container"> <div class="js-form-type-select"> <select class="dropdown-select text-dark-gray js-search-section-dropdown mr-2 pl-4 pr-5" id="edit-search-type" name="search_type" aria-label="Select search type"> <option value="products">Products</option> <option value="resources">Resources</option> </select> </div> <input placeholder="Search keyword, molecule name, target, catalog number, or product type..." autocomplete="off" class="form-control js-search-bar form-autocomplete form-text required ui-autocomplete-input" title="Search keyword, molecule name, target, catalog number, or product type..." data-autocomplete-path="/ajax/product-search/auto-suggest" type="text" id="product-search-keywords" name="keywords" value="" size="60" maxlength="256" required="required" aria-required="true" data-once="autocomplete" spellcheck="false"> <div class="form-actions" id="edit-actions"> <div class="input-group-append"> <input class="form-submit" type="submit" value=""> </div> </div> </div> </form> </div> </div> </div> </div> </section> </div> </div> </div> </div> </section> <section id="site-header__bottom"> <div class="container-fluid container-wide"> <div class="row"> <div class="col-md-12">  <nav id="main-nav"> <div> <div id="block-bio-techne-global-mainmenublock" class="main_menu_block"> <nav role="navigation" aria-labelledby="block-main-menu" id="block-main-menu" class="contextual-region navbar navbar-expand-md navbar-dark"> <div class="collapse navbar-collapse" id="navbarSupportedContent" data-date="2024-11-21 07:11:43"> <ul class="navbar-nav ml-auto"> <li class="nav-item dropdown d-md-none"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-quick-order" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Quick Order <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-quick-order" aria-labelledby="navbarDropdown-quick-order"> <div class="row"> <a href="/commerce/quickorder" class="dropdown-item text-wrap" title="Quick order form" data-drupal-link-system-path="commerce/quickorder">Quick Order Form</a> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-research-products" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Research Products <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-research-products" aria-labelledby="navbarDropdown-research-products"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Reagents & Kits<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/reagents/antibodies" class="dropdown-item text-wrap" data-drupal-link-system-path="node/276">Antibodies</a> <a href="/reagents/cell-culture-reagents" class="dropdown-item text-wrap" data-drupal-link-system-path="node/156">Cell Culture Reagents</a> <a href="/reagents/compound-libraries" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1096">Compound Libraries</a> <a href="/reagents/elisa-kits" class="dropdown-item text-wrap" data-drupal-link-system-path="node/176">ELISA Kits</a> <a href="/reagents/elispot-kits" class="dropdown-item text-wrap" data-drupal-link-system-path="node/141">ELISpot Kits</a> <a href="/reagents/enzymes" class="dropdown-item text-wrap" data-drupal-link-system-path="node/246">Enzymes</a> <a href="/reagents/fluorescent-dyes-probes" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6191">Fluorescent Dyes and Probes</a> <a href="/reagents/luminex-assays" class="dropdown-item text-wrap" data-drupal-link-system-path="node/181">Luminex Assays</a> <a href="/reagents/proteins" class="dropdown-item text-wrap" data-drupal-link-system-path="node/236">Proteins</a> <a href="/reagents/proteome-profiler-antibody-arrays" class="dropdown-item text-wrap" data-drupal-link-system-path="node/206">Proteome Profiler Antibody Arrays</a> <a href="/reagents/rnascope-ish-technology" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1626">RNAscope ISH Probes & Assays</a> <a href="/reagents/simple-plex-immunoassays" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1531">Simple Plex Immunoassays</a> <a href="/reagents/small-molecules-and-peptides" class="dropdown-item text-wrap" data-drupal-link-system-path="node/371">Small Molecules & Inhibitors</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> GMP Products<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/gmp-products/gmp-proteins" class="dropdown-item text-wrap" data-drupal-link-system-path="node/511">GMP Proteins</a> <a href="/gmp-products/gmp-small-molecules" class="dropdown-item text-wrap" data-drupal-link-system-path="node/366">GMP Small Molecules</a> <a href="/gmp-products/gmp-antibodies" class="dropdown-item text-wrap" data-drupal-link-system-path="node/13266">GMP Antibodies</a> <a href="/gmp-products/gmp-capabilities" class="dropdown-item text-wrap" title="GMP Capabilities" data-drupal-link-system-path="node/1071">GMP Capabilities</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Instruments<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/brands/proteinsimple" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3281">ProteinSimple Instruments</a> <a href="/instruments/ice" title="Our capillary electrophoresis instruments (icIEF and CE-SDS) provide reproducible quantitative analysis for thorough therapeutic protein characterization." class="dropdown-item text-wrap" data-drupal-link-system-path="node/256">iCE Maurice</a> <a href="/instruments/imagers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/536">Imagers</a> <a href="/instruments/luminex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/241">Luminex</a> <a href="/instruments/micro-flow-imaging" class="dropdown-item text-wrap" data-drupal-link-system-path="node/526">Micro-Flow Imaging</a> <a href="/instruments/simple-plex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/541">Simple Plex Ella</a> <a href="/instruments/simple-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/521">Simple Western</a> <a href="/instruments/single-cell-dispensers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6361">Single Cell Dispensers</a> <a href="/instruments/single-cell-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/531">Single-Cell Western</a> <a href="/instruments" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6731">View All Instruments</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Applications<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/methods/bioprocessing" class="dropdown-item text-wrap">Bioprocessing</a> <a href="/applications/crispr" class="dropdown-item text-wrap" data-drupal-link-system-path="node/9356">CRISPR</a> <a href="/applications/electrophysiology" class="dropdown-item text-wrap" data-drupal-link-system-path="node/426">Electrophysiology</a> <a href="/applications/flow-cytometry" class="dropdown-item text-wrap" data-drupal-link-system-path="node/321">Flow Cytometry</a> <a href="/applications/imaging" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10181">Imaging </a> <a href="/applications/immunoassays" class="dropdown-item text-wrap" data-drupal-link-system-path="node/496">Immunoassays</a> <a href="/resources/instrument-applications" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3341">Instrument Applications</a> <a href="/applications/mass-cytometry" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10071">Mass Cytometry (CyTOF)</a> <a href="/applications/spatial-biology" class="dropdown-item text-wrap" data-drupal-link-system-path="node/13171">Spatial Biology</a> <a href="/applications/vaccine-development" class="dropdown-item text-wrap" data-drupal-link-system-path="node/566">Vaccine Development</a> <a href="/applications/western-blotting" class="dropdown-item text-wrap" data-drupal-link-system-path="node/281">Western Blotting</a> <a href="/applications" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6736">View All Applications</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Research Areas<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/research-areas/cancer" class="dropdown-item text-wrap" data-drupal-link-system-path="node/8791">Cancer</a> <a href="/research-areas/cell-biology" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10661">Cell Biology</a> <a href="/research-areas/cell-and-gene-therapy" class="dropdown-item text-wrap" data-drupal-link-system-path="node/51">Cell & Gene Therapy</a> <a href="/research-areas/coronavirus" class="dropdown-item text-wrap" data-drupal-link-system-path="node/576">COVID-19</a> <a href="/research-areas/epigenetics" class="dropdown-item text-wrap" data-drupal-link-system-path="node/9511">Epigenetics</a> <a href="/research-areas/hypoxia" class="dropdown-item text-wrap" data-drupal-link-system-path="node/8846">Hypoxia</a> <a href="/research-areas/immunology" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10601">Immunology</a> <a href="/research-areas/immuno-oncology" class="dropdown-item text-wrap" data-drupal-link-system-path="node/381">Immuno-Oncology</a> <a href="/research-areas/metabolism" class="dropdown-item text-wrap" data-drupal-link-system-path="node/406">Metabolism</a> <a href="/research-areas/neuroscience" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10591">Neuroscience</a> <a href="/research-areas/organoids-3d-culture" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1452">Organoid and 3-D Culture</a> <a href="/research-areas/stem-cells" class="dropdown-item text-wrap" data-drupal-link-system-path="node/161">Stem Cells</a> <a href="/research-areas/targeted-protein-degradation" class="dropdown-item text-wrap" data-drupal-link-system-path="node/376">Targeted Protein Degradation</a> <a href="/research-areas" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6741">View All Research Areas</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-therapeutic-manufacturing" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Therapeutic Manufacturing <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-therapeutic-manufacturing" aria-labelledby="navbarDropdown-therapeutic-manufacturing"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Reagents & Kits<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/reagents/cell-culture-reagents/serum-free-animal-free" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3576">Animal-Free Cell Culture</a> <a href="/reagents/elisa-kits" class="dropdown-item text-wrap" data-drupal-link-system-path="node/176">ELISA Kits</a> <a href="/therapeutic-manufacturing/simple-plex-assays" class="dropdown-item text-wrap" title="Bioprocess impurities and immunotitration" data-drupal-link-system-path="node/1311">Simple Plex Immunoassays</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> GMP Products<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/gmp-products/gmp-proteins" class="dropdown-item text-wrap" data-drupal-link-system-path="node/511">GMP Proteins</a> <a href="/gmp-products/gmp-small-molecules" class="dropdown-item text-wrap" data-drupal-link-system-path="node/366">GMP Small Molecules</a> <a href="/gmp-products/gmp-antibodies" class="dropdown-item text-wrap" data-drupal-link-system-path="node/13266">GMP Antibodies</a> <a href="/gmp-products/gmp-capabilities" class="dropdown-item text-wrap" title="GMP Capabilities" data-drupal-link-system-path="node/1071">GMP Capabilities</a> <a href="/gmp-products/ruo-to-gmp" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3421">Transition to GMP </a> <a href="/gmp-products/loa-request" class="dropdown-item text-wrap" data-drupal-link-system-path="node/13326">DMF/LOA Request</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Instruments<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/brands/proteinsimple" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3281">ProteinSimple Instruments</a> <a href="/instruments/ice" class="dropdown-item text-wrap" data-drupal-link-system-path="node/256">iCE Maurice</a> <a href="/instruments/imagers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/536">Imagers</a> <a href="/instruments/luminex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/241">Luminex</a> <a href="/instruments/micro-flow-imaging" class="dropdown-item text-wrap" data-drupal-link-system-path="node/526">Micro-Flow Imaging</a> <a href="/instruments/simple-plex" class="dropdown-item text-wrap" data-drupal-link-system-path="node/541">Simple Plex Ella</a> <a href="/instruments/simple-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/521">Simple Western</a> <a href="/instruments/single-cell-dispensers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6361">Single Cell Dispensers</a> <a href="/instruments/single-cell-western" class="dropdown-item text-wrap" data-drupal-link-system-path="node/531">Single Cell Western</a> <a href="/instruments" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6731">View All Instruments</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Applications<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/methods/bioprocessing" class="dropdown-item text-wrap">Bioprocessing</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Research Areas<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/research-areas/cell-and-gene-therapy" class="dropdown-item text-wrap" data-drupal-link-system-path="node/51">Cell & Gene Therapy</a> <a href="/applications/immuno-oncology-clinical" class="dropdown-item text-wrap" data-drupal-link-system-path="node/2066">Immuno-Oncology</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-diagnostics" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Diagnostics <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-diagnostics" aria-labelledby="navbarDropdown-diagnostics"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Controls & Reagents<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/clinical-quality-controls" class="dropdown-item text-wrap" data-drupal-link-system-path="node/7606">Clinical Quality Controls</a> <a href="/diagnostics/molecular-quality-controls" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5596">Molecular Controls</a> <a href="/diagnostics/controls-reagents/rnascope-ish-probe-high-risk-hpv" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5981">RNAscope™ ISH Probe High Risk HPV</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Kits<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/amplidex-genetic-testing-kits" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5581">Genetics</a> <a href="/diagnostics/quantidex-oncology-testing-kits" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5586">Oncology</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Technology<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/exosome" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5486">Exosome Platform</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> OEM Services<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/ivd-assay-development" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10881">IVD Assay Development</a> <a href="/diagnostics/ivd-contract-manufacturing" class="dropdown-item text-wrap" data-drupal-link-system-path="node/7381">IVD Contract Manufacturing</a> <a href="/diagnostics/molecular-quality-controls/oem-and-commercial-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6781">Molecular Diagnostic OEM Services</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Companion Diagnostics<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/diagnostics/companion-diagnostics" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5631">Companion Diagnostics Services</a> <a href="/diagnostics/companion-diagnostics/multiomics" class="dropdown-item text-wrap" data-drupal-link-system-path="node/10616">Multiomics Platform</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-services" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Services <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-services" aria-labelledby="navbarDropdown-services"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Custom Quotes<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/bulk-quotes" class="dropdown-item text-wrap" data-drupal-link-system-path="services/bulk-quotes">Bulk Quote Discounts</a> <a href="/services/custom-formulation" class="dropdown-item text-wrap" data-drupal-link-system-path="services/custom-formulation">Custom Formulation Quotes</a> <a href="/reagents/rnascope-ish-technology/probes/custom" class="dropdown-item text-wrap" data-drupal-link-system-path="node/12571">RNAscope Custom Probe Design Quote</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Custom Services<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/custom-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1891">All Custom Services</a> <a href="/services/custom-antibody-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/906">Custom Antibody Services</a> <a href="/services/custom-cell-and-gene-therapy-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1281">Custom Cell & Gene Therapy Services</a> <a href="/services/custom-compound-library-service" class="dropdown-item text-wrap" data-drupal-link-system-path="node/2126">Custom Compound Library Services</a> <a href="/services/custom-elisa-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/261">Custom ELISA Services</a> <a href="/services/gene-engineering-services-tcbuster" class="dropdown-item text-wrap" title="Gene Engineering Services: Bio-Techne" data-drupal-link-system-path="node/1136">Custom Gene Engineering Services</a> <a href="/services/custom-luminex-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/271">Custom Luminex Services</a> <a href="/services/custom-protein-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1441">Custom Protein Services</a> <a href="/services/custom-simple-plex-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6296">Custom Simple Plex Services</a> <a href="/services/custom-targeted-protein-degradation-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/861">Custom Targeted Protein Degradation Services</a> <a href="/services/professional-assay-services-rnascope" class="dropdown-item text-wrap" data-drupal-link-system-path="node/12306">RNAscope Professional Assay Services</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Instrument Services<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/certified-service-provider-program" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5446">Certified Service Provider (CSP) Program</a> <a href="/resources/instrument-services" class="dropdown-item text-wrap" data-drupal-link-system-path="node/5471">Contract Services</a> <a href="/services/instrument-services/simple-western-service-plans" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3181">Simple Western Service Plans</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Licensing<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/services/biotechnology-licensing-partnering" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1101">Biotechnology Licensing and Partnering</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-resources" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> Resources <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-resources" aria-labelledby="navbarDropdown-resources"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Product & Instrument Tools<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/resources/cofa-finder-tool" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/cofa-finder-tool">Certificate of Analysis (COA) Finder Tool</a> <a href="/resources/calculators" class="dropdown-item text-wrap" data-drupal-link-system-path="node/7416">Calculators</a> <a href="/resources/flow-cytometry-panel-builder" class="dropdown-item text-wrap" data-drupal-link-system-path="node/8821">Flow Cytometry Panel Builder</a> <a href="/luminex-assay-customization-tool" class="dropdown-item text-wrap" data-drupal-link-system-path="luminex-assay-customization-tool">Luminex Assay Customization Tool</a> <a href="/resources/product-insert-lookup-tool" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/product-insert-lookup-tool">Product Insert Lookup Tool</a> <a href="/resources/rnascope-citations" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/rnascope-citations">RNAscope Citations</a> <a href="/resources/simple-plex-panel-builder" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/simple-plex-panel-builder">Simple Plex Panel Builder</a> <a href="/resources/simple-western-kit-builder" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/simple-western-kit-builder">Simple Western Kit Builder</a> <a href="/resources/simple-western-antibody-database" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/simple-western-antibody-database">Simple Western Antibody Database</a> <a href="/resources/single-cell-western-antibody-database" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/single-cell-western-antibody-database">Single-Cell Western Antibody Database</a> <a href="/resources/spectra-viewer" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6176">Spectra Viewer</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Scientific Resources<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/resources/blogs" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/blogs">Blogs</a> <a href="/resources/literature" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/literature">Literature</a> <a href="/resources/podcasts/biotech-podcast-back-of-the-napkin" class="dropdown-item text-wrap" data-drupal-link-system-path="node/8601">Podcasts</a> <a href="/resources/protocols-troubleshooting" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/protocols-troubleshooting">Protocols & Troubleshooting</a> <a href="/resources/scientific-articles" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/scientific-articles">Scientific Articles</a> <a href="/resources/signal-transduction-pathways" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/signal-transduction-pathways">Signal Transduction Pathways</a> <a href="/resources/testimonials" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/testimonials">Testimonials & Interviews</a> <a href="/resources/webinars" class="dropdown-item text-wrap" data-drupal-link-system-path="node/1596">Webinars</a> <a href="/resources/videos" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/videos">Videos</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Instrument Resources<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/resources/instrument-applications" class="dropdown-item text-wrap" data-drupal-link-system-path="node/3341">Instrument Applications</a> <a href="/resources/instrument-citations" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/instrument-citations">Instrument Citations</a> <a href="/resources/protocols" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/protocols">Instrument Protocols</a> <a href="/resources/instrument-software-download-center" class="dropdown-item text-wrap" data-drupal-link-system-path="resources/instrument-software-download-center">Instrument Software</a> </div> </div> </div> </div> </div> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdown-about" data-toggle="dropdown" role="button" aria-haspopup="true" aria-expanded="false"> About <span class="icon-bt-icon-caret-cropped menu-caret js-caret d-inline-block"></span> </a> <div class="dropdown-menu dropdown-menu-about" aria-labelledby="navbarDropdown-about"> <div class="row"> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> About Us<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/welcome-to-bio-techne" class="dropdown-item text-wrap" data-drupal-link-system-path="node/876">Welcome to Bio-Techne.com!</a> <a href="/about/about-bio-techne" class="dropdown-item text-wrap" data-drupal-link-system-path="node/16">About Bio-Techne</a> <a href="/brands" class="dropdown-item text-wrap" data-drupal-link-system-path="node/46">Bio-Techne Brands</a> <a href="/about/corporate-and-social-responsibility" class="dropdown-item text-wrap" data-drupal-link-system-path="node/61">Corporate & Social Responsibility</a> <a href="https://investors.bio-techne.com/" target="_blank" class="dropdown-item text-wrap">Investor Relations</a> <a href="/about/quality" class="dropdown-item text-wrap" data-drupal-link-system-path="node/6056">Quality</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Latest at Bio-Techne<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/about/careers" class="dropdown-item text-wrap" data-drupal-link-system-path="node/21">Careers</a> <a href="/about/events" class="dropdown-item text-wrap" data-drupal-link-system-path="node/786">Events</a> <a href="/programs" class="dropdown-item text-wrap" data-drupal-link-system-path="node/4621">Programs & Promotions</a> </div> </div> </div> <div class="col sub-menu-wrapper"> <div class="sub-menu-header"> Support<span class="icon-keyboard_arrow_down submenu-caret"></span> <hr/> <div class="menu-children-wrap sub-menu-box"> <a href="/support/contact-us" class="dropdown-item text-wrap" data-drupal-link-system-path="node/96">Contact & Support</a> <a href="/distributors" class="dropdown-item text-wrap" data-drupal-link-system-path="node/9936">Distributors</a> </div> </div> </div> </div> </div> </li> </ul> </div> </nav> </div> </div> </nav> </div> </div> </div> </section> </div> <section class="paragraph paragraph--type--hero-banner paragraph--view-mode--full paragraph-background-color--dark"> <div class="banner_background_image no-lazy-load" style="background: linear-gradient(to top, rgba(0, 0, 0, 0.0) 0%, rgba(0, 0, 0, 0.90) 100%), url('https://resources.bio-techne.com/bio-techne-assets/images/banners/flt-3l-hero_banner.png'); background-position: top center; background-repeat: no-repeat; background-size: cover;"> <div> <div class="paragraph paragraph--type--h1-2-2-text-to-media paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:h1_2_2_text_to_media:field_indv_h1"> <div><h1>Proteins for Stem Cell Culture</h1></div> </div> <div class="field_block:paragraph:h1_2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Optimize your stem cell cultures with R&D Systems™ cytokines and growth factors. Our proteins provide high levels of bioactivity and lot-to-lot consistency so you can have confidence in their ability to promote robust stem cell expansion and differentiation with minimal variability between cultures. From basic research to preclinical applications, we offer research-grade, Animal-Free™, and GMP-grade cytokines to meet all of your experimental needs.</p></div> </div> <div class="field_block:paragraph:h1_2_2_text_to_media:field_call_to_action_global"> <a href="#pluripotent" class="btn btn-primary" type="link"> Browse Proteins for Stem Cell Culture </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:h1_2_2_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/stry0169707_obt_hero_solo_v4.png" alt="Proteins for Stem Cell Research Solo" fetchpriority="high" > </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> </div> </header> </div> <div id="main" class="container-fluid container-wide"> <div class="row"> <div class="col-md-12"> <div> <div id="block-bio-techne-global-breadcrumbs" class="system_breadcrumb_block"> <nav role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/reagents">Bio-Techne Reagents</a> </li> <li> <a href="/reagents/proteins">Proteins</a> </li> <li> Proteins For Stem Cell Research </li> </ol> </nav> </div> </div> </div> </div> <main> <section class="section"> <div> <div id="block-bio-techne-global-content" class="system_main_block"> <article> <div> <div> <div> <div class="paragraph accordion mb-4 paragraph--type--extendable-paragraph paragraph--view-mode--default"> <div class="card-header rounded-top bg-white"> <a class="collapsed" data-toggle="collapse" href="#expPara-optimizing-stem-cell-culture-conditions7" role="button" aria-expanded="false" aria-controls="expPara"> <h5>Optimizing Stem Cell Culture Conditions</h5> </a> </div> <div class="collapse" id="expPara-optimizing-stem-cell-culture-conditions7" aria-expanded="false" aria-controls="expPara"> <div class="card-body p-4"> <br/> <div><p>Stem cells are characterized as precursor cells that have the ability to self-renew and differentiate into multiple mature cell types. Many different stems cell types have been identified including embryonic stem cells, adult stem cells, hematopoietic stem cells, mesenchymal stem cells, and neural stem cells. These cells are being widely studied due to their potential applications in regenerative medicine and cellular therapies, as well as disease modeling and drug discovery.</p> <p>Most stem cell studies rely on the ability to isolate and culture different stem cell types <em>in vitro</em>, which can be technically challenging. As a result, the first step in working with stem cells is typically identifying and optimizing appropriate culture conditions. Different stem cell types require specialized culture conditions to either expand the cells <em>in vitro</em> or promote their differentiation into specific cell lineages. Once appropriate culture conditions are identified, researchers have to confirm that these conditions are reproducible, so that they can standardize their protocols and minimize variability from one experiment to the next.</p> <p>Cytokines and growth factors are some of the most important components of stem cell cultures. Different combinations of these factors are commonly used to promote either self-renewal or differentiation into specific cell lineages. As a result, the proteins added to stem cell cultures need to display high levels of activity, lot-to-lot consistency, and be free of contaminants to ensure that they efficiently drive the desired experimental outcome and contribute to the establishment of optimal, reproducible culture conditions. R&D Systems understands the importance of consistency and reproducibility in cell cultures. Our rigorous in-house testing and quality control specifications are designed to ensure that our proteins will provide the highest levels of performance, low endotoxin levels (<0.1 EU/ug), and minimal lot-to-lot variability. With over 30 years of experience purifying and manufacturing recombinant proteins, we offer stability of source and the expertise necessary to provide superior products that allow researchers to be confident in their stem cell culture conditions and the data that they generate.</p></div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--clickable-icons-container paragraph--view-mode--default"> <div class="container"> <div class="row"> <div class="col p-0 "> <h2></h2> </div> </div> <div class="row"> <div class="col "> </div> </div> <div class="row"> <div class="row"> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#pluripotent" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/pluripotent-stem-cells-150x150.png' alt='Pluripotent Stem Cells Icon'></div> </article> </div> <p><strong>Pluripotent Stem Cells</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#neural" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/neural-stem-cells-150x150.png' alt='Neural Stem Cells Icon'></div> </article> </div> <p><strong>Neural Stem Cells</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#mesenchymal" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/mesenchymal-stem-cells-150x150.png' alt='Mesenchymal Stem Cells Icon'></div> </article> </div> <p><strong>Mesenchymal Stem Cells</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#hematopoietic" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/hematopoietic-stem-cells-150x150.png' alt='Hematopoietic Stem Cells Icon'></div> </article> </div> <p><strong>Hematopoietic Stem Cells</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="/research-areas/organoids-3d-culture" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/organoid-3d-cell-culture-150x150.png' alt='Organoid 3D Cell Culture Icon'></div> </article> </div> <p><strong>Organoid and 3-D Cell Culture</strong></p> </a> </div> </div> <div class="col-xl-2 col-lg-2 col-md-4 col-sm-6 col-6 mb-4"> <div class="paragraph paragraph--type--indvidual-clickable-icon paragraph--view-mode--default card p-3 text-center h-100 mb-0"> <a href="#otherstemcell" > <div><article> <div><img src='https://resources.bio-techne.com/bio-techne-assets/images/icons/additional-stem-cell-related-products-150x150.png' alt='Additional Stem Cell-Related Products Icon'></div> </article> </div> <p><strong>Additional Stem Cell-Related Products</strong></p> </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="thin-banner banner_wrapper"> <div class="banner-dark"> <div> <div><h2>Bulk Protein Quantities Are Available at Discounted Prices</h2></div> <a href="/services/custom-protein-services/bulk-protein-reagents" > <button type="button" class="btn btn-primary"> Request a Bulk Quote </button> </a> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-text-to-media mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_header_2_global"> <div><h3>Several Stem Cell Core Facility Directors Explain Why They Choose R&D Systems Cytokines</h3></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Directors at several different stem cell core facilities describe their experiences using R&D Systems cytokines and growth factors. The speakers on the video include Sunita D’Souza, Director of the Center for Modern Pediatric Diseases at St. Jude’s Medical Center, Deborah French, Director of the Human Pluripotent Stem Cell Core at the Children’s Hospital of Philadelphia, Barbara Corneo, Director of the Stem Cell Core Facility at Columbia University Medical School, and Wenli Yang, Director of the iPSC Core Facility at the University of Pennsylvania. Learn why they use R&D Systems cytokines for their research. <a name="pluripotent"></a></p></div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_indv_media"> <div> <article> <div class="youtube-video-place"> <lite-youtube videoid="IUydCoe0yvQ" params="rel=0" style="background-image: url('https://img.youtube.com/vi/IUydCoe0yvQ/maxresdefault.jpg');"> <a href="https://www.youtube.com/embed/IUydCoe0yvQ?autoplay=1" class="lty-playbtn" title="Stem Cell Core Testimonials for Proteins and Small Molecules"> <span class="lyt-visually-hidden">Stem Cell Core Testimonials for Proteins and Small Molecules</span> </a> </lite-youtube> </div> </article> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="pluripotent"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Pluripotent Stem Cells</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><h3>Cytokines for ESC and iPSC Expansion - Products by Molecule</h3> <figure class="responsive-figure-table"><table class="table table-bordered"> <tbody> <tr> <td><a href="/search?keywords=activin%20a&common_name=Activin%20A&category_attr=Proteins%20and%20Enzymes">Activin A</a> *</td> <td><a href="/search?keywords=bmp-4&common_name=BMP-4&category_attr=Proteins%20and%20Enzymes">BMP-4</a> *</td> <td><a href="/search?keywords=fgf%20basic&common_name=FGF%20basic/FGF2/bFGF&category_attr=Proteins%20and%20Enzymes">FGF basic/FGF2</a> *</td> <td><a href="/search?keywords=nodal&common_name=Nodal&category_attr=Proteins%20and%20Enzymes">Nodal</a></td> <td><a href="/search?keywords=tgf-beta%201%20&common_name=TGF-beta%201&category_attr=Proteins%20and%20Enzymes">TGF-beta 1</a> *</td> <td><a href="/search?keywords=wnt-3a%20&common_name=Wnt-3a&sub_category=Recombinant%20Proteins">Wnt-3a</a> *</td> </tr> </tbody> </table></figure> <h3>Cytokines for Ectoderm Lineage Differentiation - Products by Molecule</h3> <figure class="responsive-figure-table"><table class="table table-bordered"> <tbody> <tr> <td><a href="/search?keywords=bmp-4&common_name=BMP-4&category_attr=Proteins%20and%20Enzymes">BMP-4</a> *</td> <td><a href="/search?keywords=egf&common_name=EGF&category_attr=Proteins%20and%20Enzymes">EGF</a> *</td> <td><a href="/search?keywords=fgf%20basic&common_name=FGF%20basic/FGF2/bFGF&category_attr=Proteins%20and%20Enzymes">FGF basic/FGF-2</a> *</td> <td><a href="/search?keywords=noggin&common_name=Noggin&category_attr=Proteins%20and%20Enzymes">Noggin</a> *</td> </tr> </tbody> </table></figure> <h3>Cytokines for Mesoderm Lineage Differentiation - Products by Molecule</h3> <figure class="responsive-figure-table"><table class="table table-bordered"> <tbody> <tr> <td><a href="/search?keywords=activin%20a&common_name=Activin%20A&category_attr=Proteins%20and%20Enzymes">Activin A</a> *</td> <td><a href="/search?keywords=bmp-2&common_name=BMP-2&category_attr=Proteins%20and%20Enzymes">BMP-2</a> *</td> <td><a href="/search?keywords=bmp-4&common_name=BMP-4&category_attr=Proteins%20and%20Enzymes">BMP-4</a> *</td> <td><a href="/search?keywords=dkk-1&common_name=Dkk-1&category_attr=Proteins%20and%20Enzymes">Dkk-1</a></td> </tr> <tr> <td><a href="/search?keywords=fgf%20basic&common_name=FGF%20basic/FGF2/bFGF&category_attr=Proteins%20and%20Enzymes">FGF basic/FGF2</a> *</td> <td><a href="/search?keywords=fgf-3&common_name=FGF-3&category_attr=Proteins%20and%20Enzymes">FGF-3</a></td> <td><a href="/search?keywords=fgf-10&common_name=FGF-10&category_attr=Proteins%20and%20Enzymes">FGF-10</a></td> <td><a href="/search?keywords=fgf-17&common_name=FGF-17&category_attr=Proteins%20and%20Enzymes">FGF-17</a></td> </tr> <tr> <td><a href="/search?keywords=flt-3%20ligand&common_name=Flt-3%20Ligand/FLT3L&category_attr=Proteins%20and%20Enzymes">Flt-3 Ligand</a> *</td> <td><a href="/search?keywords=il-3&common_name=IL-3&category_attr=Proteins%20and%20Enzymes">IL-3</a> *</td> <td><a href="/search?keywords=il-6&common_name=IL-6&category_attr=Proteins%20and%20Enzymes">IL-6</a> *</td> <td><a href="/search?keywords=il-11&common_name=IL-11&category_attr=Proteins%20and%20Enzymes">IL-11</a></td> </tr> <tr> <td><a href="/search?keywords=noggin&common_name=Noggin&category_attr=Proteins%20and%20Enzymes">Noggin</a> *</td> <td><a href="/search?keywords=pdgf-bb&common_name=PDGF-BB&category_attr=Proteins%20and%20Enzymes">PDGF-BB</a> *</td> <td><a href="/search?keywords=scf&common_name=SCF/c-kit%20Ligand&category_attr=Proteins%20and%20Enzymes">SCF/c-kit Ligand</a> *</td> <td><a href="/search?keywords=tgf-beta%201&common_name=TGF-beta%201&category_attr=Proteins%20and%20Enzymes">TGF-beta 1</a> *</td> </tr> <tr> <td><a href="/search?keywords=thrombopoietin&common_name=Thrombopoietin/Tpo&category_attr=Proteins%20and%20Enzymes">Thrombopoietin/TPO</a> *</td> <td><a href="/search?keywords=vegf&common_name=VEGF&category_attr=Proteins%20and%20Enzymes">VEGF</a>*</td> <td><a href="/search?keywords=wnt-5a&common_name=Wnt-5a&category_attr=Proteins%20and%20Enzymes">Wnt-5a</a></td> <td> </td> </tr> </tbody> </table></figure> <h3>Cytokines for Endoderm Lineage Differentiation - Products by Molecule</h3> <figure class="responsive-figure-table"><table class="table table-bordered"> <tbody> <tr> <td><a href="/search?keywords=activin%20a&common_name=Activin%20A&category_attr=Proteins%20and%20Enzymes">Activin A</a> *</td> <td><a href="/search?keywords=bmp-4&common_name=BMP-4&category_attr=Proteins%20and%20Enzymes">BMP-4</a> *</td> <td><a href="/search?keywords=egf&common_name=EGF&category_attr=Proteins%20and%20Enzymes">EGF</a> *</td> <td><a href="/search?keywords=fgf%20basic&common_name=FGF%20basic/FGF2/bFGF&category_attr=Proteins%20and%20Enzymes">FGF basic/FGF-2</a> *</td> </tr> <tr> <td><a href="/search?keywords=fgf-4&common_name=FGF-4&category_attr=Proteins%20and%20Enzymes">FGF-4</a></td> <td><a href="/search?keywords=fgf-7&common_name=KGF/FGF-7&category_attr=Proteins%20and%20Enzymes">FGF-7/KGF</a> *</td> <td><a href="/search?keywords=fgf-10&common_name=FGF-10&category_attr=Proteins%20and%20Enzymes">FGF-10</a></td> <td><a href="/search?keywords=fgf-18&common_name=FGF-18&category_attr=Proteins%20and%20Enzymes">FGF-18</a></td> </tr> <tr> <td><a href="/search?keywords=hgf&common_name=HGF&category_attr=Proteins%20and%20Enzymes">HGF</a> *</td> <td><a href="/search?keywords=igf-1&common_name=IGF-I/IGF-1&category_attr=Proteins%20and%20Enzymes">IGF-I/IGF-1</a> *</td> <td><a href="/search?keywords=noggin&common_name=Noggin&category_attr=Proteins%20and%20Enzymes">Noggin</a> *</td> <td><a href="/search?keywords=pdgf-bb&common_name=PDGF-BB&category_attr=Proteins%20and%20Enzymes">PDGF-BB</a> *</td> </tr> <tr> <td><a href="/search?keywords=shh&common_name=Sonic%20Hedgehog/Shh&category_attr=Proteins%20and%20Enzymes">Sonic Hedgehog/Shh</a> *</td> <td><a href="/search?keywords=vegf&common_name=VEGF&category_attr=Proteins%20and%20Enzymes">VEGF</a>*</td> <td><a href="/search?keywords=wnt-3a&common_name=Wnt-3a&category_attr=Proteins%20and%20Enzymes">Wnt-3a</a> *</td> <td> </td> </tr> </tbody> </table></figure> <p>*<a href="/gmp-products/gmp-proteins">GMP-grade Proteins</a> are available for these molecules.</p></div> </div> </div> </div> </div> </div> <div> <div class="thin-banner banner_wrapper"> <div class="banner-dark"> <div> <div><h2>Our Cultrex™ BME Matrices are in Stock and Ready to Ship!</h2></div> <a href="/reagents/cell-culture-reagents/cultrex-bme-and-ecm-proteins/sample-request" > <button type="button" class="btn btn-primary"> Request a BME Matrix Sample </button> </a> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <a href="https://www.bio-techne.com/p/cell-culture/excellerate-ipsc-expansion-medium_ccm036" title="Try Our ExCellerate iPSC Expansion Medium" > <img src="https://resources.bio-techne.com/bio-techne-assets/images/products/excellerate-ipsc-expansion-medium-525x315.png" alt="ExCellerate iPSC Expansion Medium" loading="lazy" > </a> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_header_2_global"> <div><h4>New ExCellerate iPSC Expansion Medium</h4></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>Supports robust expansion and maintenance of pluripotent stem cell culture for enhanced consistency and reproducibility.</p> <ul> <li>Animal component-free</li> <li>No growth factor supplementation required</li> <li>Stable cell integrity over long term culture</li> </ul></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_call_to_action_global"> <a href="/p/cell-culture/excellerate-ipsc-expansion-medium_ccm036" class="btn btn-primary" type="link"> Try Our ExCellerate iPSC Expansion Medium </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--button-row paragraph--view-mode--default"> <div class="row"> <div class="col"> <div class="list-grid-wrap"> <div class="row"> <div class="col-md-4"> <a href="/search?keywords=cytokinegrowthfact&category_attr=Proteins%20and%20Enzymes" class="btn btn-primary" type="link"> Browse Our Complete Collection of Cytokines and Growth Factors </a> </div> <div class="col-md-4"> <a href="/search?keywords=animal-free%20recombinant%20proteins&sub_category=Animal-Free%20Recombinant%20Proteins" class="btn btn-primary" type="link"> Search Our Catalog of Animal-Free Recombinant Proteins </a> </div> <div class="col-md-4"> <a href="/gmp-proteins" class="btn btn-primary" type="link"> Explore Our Portfolio of GMP-grade Recombinant Proteins </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h3>Assessment of the Bioactivity of R&D Systems Recombinant Human FGF2 and Wnt-3a</h3></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/recombinant-human-FGF2-Wnt-3a.png" alt="A. Assessment of the bioactivity of R&D Systems Recombinant Human FGF basic and comparent with a top competitor’s FGF basic. B. Data image from Catalog # 5036-WN " loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p><strong>R&D Systems Recombinant Human FGF basic/FGF2 (146 aa) and Recombinant Human Wnt-3a Display Higher Activity than the Same Proteins Provided by Leading Competitors.</strong></p> <p>(A) The bioactivity of R&D Systems <a href="/p/proteins-enzymes/recombinant-human-fgf-basic-fgf2-bfgf-146-aa-protein_233-fb">Recombinant Human FGF basic/FGF2 (146 aa)</a> (Catalog # 233-FB; orange line) or recombinant human FGF basic/FGF2 (146 aa) from a leading competitor (green line) was assessed by measuring the ability of the proteins to stimulate proliferation of the NR6R-3T3 mouse fibroblast cell line. The bioactivity of R&D Systems Recombinant Human FGF basic/FGF2 (146 aa) was approximately 3-fold greater than the top competitor’s FGF basic (146 aa). (B) The bioactivity of R&D Systems <a href="/p/proteins-enzymes/recombinant-human-wnt-3a-protein_5036-wn">Recombinant Human Wnt-3a</a> (Catalog # 5036-WN; orange line) or recombinant human Wnt-3a from another company (green line) was assessed by measuring the ability of the proteins to induce alkaline phosphatase production in the MC3T3-E1 mouse preosteoblast cell line. The ED<sub>50</sub> for this effect for R&D Systems Recombinant Human Wnt-3a was 1.7-fold better, with more than twice the maximum response compared to the competitor's Wnt-3a.</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h3>Differentiation of hESCs into Endoderm Induced by Recombinant Human Activin A</h3></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/data-image-3-338-v2.jpg" alt="A. Claudin-6 and Sox17 immunostaining of human embryonic stem cells differentiated into endoderm in Activin A-supplemented media B. Claudin-6 and Sox17 immunostaining of human embryonic stem cells cultured in media without Activin A" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p><strong>Differentiation of Human Embryonic Stem Cells in Media Supplemented with R&D Systems Recombinant Human Activin A.</strong></p> <p>BG01V human embryonic stem cells were (A) cultured in media without any protein added or (B) differentiated into endoderm using media supplemented with <a href="/p/proteins-enzymes/recombinant-human-mouse-rat-activin-a-protein_338-ac">Recombinant Human Activin A</a> (R&D Systems, Catalog # 338-AC). Differentiation into endoderm was confirmed by positive staining for Claudin-6 (red) and Sox17 (green) using the <a href="/p/antibodies/human-claudin-6-antibody-342927_mab3656">Mouse Anti-Human Claudin-6 Monoclonal Antibody</a> (R&D Systems, Catalog # MAB3656) and the <a href="/p/antibodies/human-sox17-antibody_af1924">Goat Anti-Human Sox17 Polyclonal Antibody</a> (R&D Systems, Catalog # AF1924), respectively. BG01V human embryonic stem cells are licensed from ViaCyte, Inc. <a name="neural"></a></p></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_call_to_action_global"> <a href="/research-areas/stem-cells/ipsc" class="btn btn-primary" type="link"> View All Pluripotent Stem Cells Products and Services </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Neural Stem Cells</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><h3>Cytokines for Neural Stem Cells - Products by Molecule</h3> <figure class="responsive-figure-table"><table class="table table-bordered"> <tbody> <tr> <td><a href="/search?keywords=bdnf&common_name=BDNF&category_attr=Proteins%20and%20Enzymes">BDNF</a></td> <td><a href="/search?keywords=bmp-2&common_name=BMP-2&category_attr=Proteins%20and%20Enzymes">BMP-2</a> *</td> <td><a href="/search?keywords=bmp-4&common_name=BMP-4&category_attr=Proteins%20and%20Enzymes">BMP-4</a> *</td> <td><a href="/search?keywords=cntf&common_name=CNTF&category_attr=Proteins%20and%20Enzymes">CNTF</a></td> <td><a href="/search?keywords=egf&common_name=EGF&category_attr=Proteins%20and%20Enzymes">EGF</a> *</td> <td><a href="/search?keywords=fgf%20basic&common_name=FGF%20basic/FGF2/bFGF&category_attr=Proteins%20and%20Enzymes">FGF basic/FGF2</a> *</td> </tr> <tr> <td><a href="/search?keywords=fgf-4&common_name=FGF-4&category_attr=Proteins%20and%20Enzymes">FGF-4</a></td> <td><a href="/search?keywords=fgf-8a&common_name=FGF-8&sub_category=Recombinant%20Proteins">FGF-8a</a></td> <td><a href="/search?keywords=fgf-8b&common_name=FGF-8&category_attr=Proteins%20and%20Enzymes">FGF-8b</a></td> <td><a href="/search?keywords=fgf-10&common_name=FGF-10&category_attr=Proteins%20and%20Enzymes">FGF-10</a></td> <td><a href="/search?keywords=gdnf&common_name=GDNF&category_attr=Proteins%20and%20Enzymes">GDNF</a> *</td> <td><a href="/search?keywords=igf-1&common_name=IGF-I/IGF-1&category_attr=Proteins%20and%20Enzymes">IGF-I/IGF-1</a> *</td> </tr> <tr> <td><a href="/search?keywords=beta-ngf&common_name=beta-NGF&category_attr=Proteins%20and%20Enzymes">beta-NGF</a></td> <td><a href="/search?keywords=noggin&common_name=Noggin&category_attr=Proteins%20and%20Enzymes">Noggin</a> *</td> <td><a href="/search?keywords=nt-4&common_name=NT-4&category_attr=Proteins%20and%20Enzymes">NT-4</a></td> <td><a href="/search?keywords=pdgf-bb&common_name=PDGF-BB&category_attr=Proteins%20and%20Enzymes">PDGF-BB</a> *</td> <td><a href="/search?keywords=shh&common_name=Sonic%20Hedgehog/Shh&category_attr=Proteins%20and%20Enzymes">Sonic Hedgehog/Shh</a> *</td> <td><a href="/search?keywords=vegf&common_name=VEGF&category_attr=Proteins%20and%20Enzymes">VEGF</a>*</td> </tr> </tbody> </table></figure> <p>*<a href="/gmp-products/gmp-proteins">GMP-grade Proteins</a> are available for these molecules.</p></div> </div> </div> <div> <div class="paragraph paragraph--type--individual-button mb-4 paragraph--view-mode--default w-100"> <div class="row"> <div class="col"> <a href="/search?keywords=cytokinegrowthfact&category_attr=Proteins%20and%20Enzymes" class="btn btn-primary float-left" type="link" > Search for Other Cytokines for Neural Stem Cell Research </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h3>Analysis of the Bioactivity and Consistency of R&D Systems Recombinant Human Noggin</h3></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/analysis-bioactivity-rnd-recombinant-human-noggin.png" alt="A. SOX1, 0tx2 staining of human embryonic stem cells differentiated to neuroectoderm with FGF basic and Recombinant Human Noggin B. Quantitation of S0X1 clusters in human embryonic stem cells incubated with R&D Systems Noggin or Noggin from 2 competitors" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p><strong>R&D Systems Recombinant Human Noggin Displays Minimal Lot-to-Lot Variability and Higher Activity than Leading Competitors’ Noggin Proteins.</strong></p> <p>BG01V human embryonic stem cells were cultured in Mouse Embryonic Fibroblast Conditioned Media supplemented with FGF basic (5 ng/mL). Stem cells were driven into early cells of the neuroectoderm using a 3-day incubation in <a href="/p/proteins-enzymes/recombinant-human-noggin-protein_6057-ng">Recombinant Human Noggin</a> (25 ug/mL) from either R&D Systems (Lot 1, Lot 2; Catalog # 6057-NG) or from two different competitors (Competitor 1, Competitor 2). Control cells were incubated in media without Noggin (No Noggin). The cells were stained for the early ectoderm marker, Otx2, and the neuroectoderm marker, SOX1. (A) Representative images of SOX1 (green), Otx2 (red), and DAPI (blue) staining in embryonic stem cells differentiated with Noggin from R&D Systems or Noggin from Competitor 2. (B) SOX1+ clusters were quantified under each of the indicated culture conditions. Cells treated with R&D Systems Noggin showed an increase in SOX1+ cells compared to both untreated and competitor-treated cells. R&D Systems Noggin showed consistent differentiation across the lots tested. BG01V human embryonic stem cells were licensed from ViaCyte, Inc. (C) The bioactivity of R&D Systems <a href="/p/proteins-enzymes/recombinant-human-noggin-protein_6057-ng">Recombinant Human Noggin</a> (Catalog # 6057-NG; orange line) or recombinant human noggin from a top competitor (green line) was determined by assessing the ability of the proteins to inhibit alkaline phosphatase production induced by 50 ng/mL<a href="/p/proteins-enzymes/recombinant-human-bmp-4-protein_314-bp">Recombinant Human BMP-4</a> (R&D Systems, Catalog # 314-BP) in the ATDC5 mouse chondrogenic cell line. In the presence of 50 ng/mL Recombinant Human BMP-4, the ED<sub>50</sub> for this effect for R&D Systems Recombinant Human Noggin was approximately 30-fold greater than the top competitor’s Noggin protein. </p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <section class="paragraph paragraph--type--full-width-banner-with-image mb-4 paragraph--view-mode--default paragraph-background-color--dark"> <div class="banner_background_image" data-bgimage="https://resources.bio-techne.com/bio-techne-assets/images/banners/black-blue-gradient-banner-1110x350.png" style="background-repeat: no-repeat;"> <div> <div> <div> <div class="paragraph paragraph--type--_-2-text-to-media mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_header_2_global"> <div><h2>Animal-Free Recombinant Proteins</h2></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Ensure a seamless transition from preclinical research into clinical manufacturing by starting your preclinical experiments with our Animal-Free RUO proteins. R&D Systems Animal-Free RUO proteins are produced in dedicated animal-free laboratories and are manufactured using the same systems as our Animal-Free GMP-Grade proteins.</p></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_call_to_action_global"> <a href="/reagents/proteins/animal-free-proteins" class="btn btn-primary" type="link"> Browse Animal-Free Proteins </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/banners/animal-free-proteins_foreground.png" alt="Animal Free Proteins Banner" loading="lazy" > </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="mesenchymal"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Mesenchymal Stem Cells</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><h3>Cytokines for Mesenchymal Stem Cells - Products by Molecule</h3> <figure class="responsive-figure-table"><table class="table table-bordered"> <tbody> <tr> <td><a href="/search?keywords=bmp-2&common_name=BMP-2&category_attr=Proteins%20and%20Enzymes">BMP-2</a> *</td> <td><a href="/search?keywords=bmp-4&common_name=BMP-4&category_attr=Proteins%20and%20Enzymes">BMP-4</a> *</td> <td><a href="/search?keywords=bmp-6&common_name=BMP-6&category_attr=Proteins%20and%20Enzymes">BMP-6</a></td> <td><a href="/search?keywords=egf&common_name=EGF&category_attr=Proteins%20and%20Enzymes">EGF</a> *</td> <td><a href="/search?keywords=fgf-2&common_name=FGF%20basic/FGF2/bFGF&category_attr=Proteins%20and%20Enzymes">FGF basic/FGF2</a> *</td> <td><a href="/search?keywords=fgf-4&common_name=FGF-4&category_attr=Proteins%20and%20Enzymes">FGF-4</a></td> </tr> <tr> <td><a href="/search?keywords=gdf-5&common_name=GDF-5/BMP-14&category_attr=Proteins%20and%20Enzymes">GDF-5/BMP-14</a></td> <td><a href="/search?keywords=hb-egf&common_name=HB-EGF&category_attr=Proteins%20and%20Enzymes">HB-EGF</a></td> <td><a href="/search?keywords=igf-1&common_name=IGF-I/IGF-1&category_attr=Proteins%20and%20Enzymes">IGF-I/IGF-1</a> *</td> <td><a href="/search?keywords=lr3%20igf-1&common_name=IGF-I/IGF-1&category_attr=Proteins%20and%20Enzymes">LR3 IGF-I/IGF-1</a> *</td> <td><a href="/search?keywords=il-6&common_name=IL-6&category_attr=Proteins%20and%20Enzymes">IL-6</a> *</td> <td><a href="/search?keywords=pdgf-bb&common_name=PDGF-BB&category_attr=Proteins%20and%20Enzymes">PDGF-BB</a> *</td> </tr> <tr> <td><a href="/search?keywords=shh&common_name=Sonic%20Hedgehog/Shh&category_attr=Proteins%20and%20Enzymes">Sonic Hedgehog/Shh</a> *</td> <td><a href="/search?keywords=tgf-beta1&common_name=TGF-beta%201&category_attr=Proteins%20and%20Enzymes">TGF-beta 1</a> *</td> <td><a href="/search?keywords=tgf-beta2&common_name=TGF-beta%202&category_attr=Proteins%20and%20Enzymes">TGF-beta 2</a></td> <td><a href="/search?keywords=tgf-beta3&common_name=TGF-beta%203&category_attr=Proteins%20and%20Enzymes">TGF-beta 3</a></td> <td><a href="/search?keywords=wnt-5b&common_name=Wnt-5b&category_attr=Proteins%20and%20Enzymes">Wnt-5b</a></td> <td><a href="/search?keywords=wnt-10b&common_name=Wnt-10b&category_attr=Proteins%20and%20Enzymes">Wnt-10b</a></td> </tr> </tbody> </table></figure> <p>*<a href="/gmp-products/gmp-proteins">GMP-grade Proteins</a> are available for these molecules.</p></div> </div> </div> <div> <div class="paragraph paragraph--type--individual-button mb-4 paragraph--view-mode--default w-100"> <div class="row"> <div class="col"> <a href="/search?keywords=cytokinegrowthfact&category_attr=Proteins%20and%20Enzymes" class="btn btn-primary float-left" type="link" > Search for Other Cytokines for Mesenchymal Stem Cell Research </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h3>Analysis of the Bioactivities of R&D Systems Recombinant Human Shh Proteins</h3></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/analysis-bioactivity-rnd-recombinant-human-shh-proteins.png" alt="A. Assessment of the activity of HEK293-purified High Activity Recombinant Shh compared with E.coli-purified Shh proteins B. LC/ESI-MS analysis of HEK293-purified High Activity Recombinant Human Shh identifies cholesterol and fatty acid modifications" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p><strong>R&D Systems Recombinant Human Sonic Hedgehog/Shh Purified from HEK293 Cells and Containing the Correct Post-Translational Modifications Displays Higher Activity than E. coli-purified Recombinant Human Shh Proteins.</strong></p> <p>(A) The bioactivity of R&D Systems <a href="/p/proteins-enzymes/recombinant-human-sonic-hedgehog-shh-protein-high-activity_8908-sh">High Activity Recombinant Human Shh</a> (Catalog # 8908-SH; green line), purified from HEK293 cells and containing the correct post-translational modifications (cholesterol and fatty acids), was compared to the bioactivity of <em>E. coli</em>-purified <a href="/p/proteins-enzymes/recombinant-human-sonic-hedgehog-shh-c24ii-n-terminus_1845-sh">Recombinant Human Shh (C24II) N-terminus</a> (R&D Systems, Catalog # 1845-SH; red line), and <em>E.coli</em>-purified <a href="/p/proteins-enzymes/recombinant-human-sonic-hedgehog-shh-n-terminus-protein_1314-sh">Recombinant Human Shh, N-terminus</a> (R&D Systems, Catalog # 1314-SH; blue line) by measuring the ability of the three proteins to induce alkaline phosphatase production by mesenchymal stem cells. The HEK293-purified High Activity Recombinant Human Shh protein was found to be over 14-fold more active than the <em>E.coli</em>-purified Recombinant Human Shh (C24II) N-Terminus protein, and over 250-fold more active than <em>E. coli</em>-purified Recombinant Human Shh-N protein. (B) LC/ESI-MS analysis of <a href="/p/proteins-enzymes/recombinant-human-sonic-hedgehog-shh-protein-high-activity_8908-sh">High Activity Recombinant Human Shh</a> (R&D Systems, Catalog # 8908-SH) shows major peaks at 20119.3, 20145.2, and 20171.6 Da, suggesting that Recombinant Human Shh molecules are dual-modified with cholesterol at the C-terminus, and fatty acids (lauric acid, myristic acid, and palmitic acid) at the N-terminus. The minor peaks at 19776 Da corresponds to Recombinant Human Shh with only the fatty acid modification.</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <section class="paragraph paragraph--type--full-width-banner-with-image mb-4 paragraph--view-mode--default paragraph-background-color--light"> <div class="banner_background_image" data-bgimage="" style="background-repeat: no-repeat;"> <div> <div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/custom-protein-services-410x410-v2.png" alt="Custom Protein Services" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_header_2_global"> <div><h2>Custom Protein Services</h2></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p>If you can’t find the protein that you need on our website, contact us. From scratch protein development to customizing a protein from our catalog, our custom services team will create the protein that fits your experimental needs. </p></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_call_to_action_global"> <a href="/services/custom-protein-services" class="btn btn-primary" type="link"> Learn More About Custom Protein Services </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="hematopoietic"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2>Hematopoietic Stem Cells</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><h3>Cytokines for Hematopoietic Stem Cells - Products by Molecule</h3> <figure class="responsive-figure-table"><table class="table table-bordered"> <tbody> <tr> <td><a href="/search?keywords=bmp-4&common_name=BMP-4&category_attr=Proteins%20and%20Enzymes">BMP-4</a> *</td> <td><a href="/search?keywords=erythropoietin&common_name=Erythropoietin/EPO&category_attr=Proteins%20and%20Enzymes">Erythropoietin</a></td> <td><a href="/search?keywords=flt-3%20ligand&common_name=Flt-3%20Ligand/FLT3L&category_attr=Proteins%20and%20Enzymes">Flt-3 Ligand</a> *</td> <td><a href="/search?keywords=g-csf&common_name=G-CSF&category_attr=Proteins%20and%20Enzymes">G-CSF</a></td> </tr> <tr> <td><a href="/search?keywords=gm-csf&common_name=GM-CSF&category_attr=Proteins%20and%20Enzymes">GM-CSF</a> *</td> <td><a href="/search?keywords=ifn-gamma&common_name=IFN-gamma&category_attr=Proteins%20and%20Enzymes">IFN-gamma</a> *</td> <td><a href="/search?keywords=il-2&common_name=IL-2&category_attr=Proteins%20and%20Enzymes">IL-2</a> *</td> <td><a href="/search?keywords=il-3&common_name=IL-3&category_attr=Proteins%20and%20Enzymes">IL-3</a> *</td> </tr> <tr> <td><a href="/search?keywords=il-4&common_name=IL-4&category_attr=Proteins%20and%20Enzymes">IL-4</a> *</td> <td><a href="/search?keywords=il-6&common_name=IL-6&category_attr=Proteins%20and%20Enzymes">IL-6</a> *</td> <td><a href="/search?keywords=il-7&common_name=IL-7&category_attr=Proteins%20and%20Enzymes">IL-7</a> *</td> <td><a href="/search?keywords=il-10&common_name=IL-10&category_attr=Proteins%20and%20Enzymes">IL-10</a></td> </tr> <tr> <td><a href="/search?keywords=il-11&common_name=IL-11&category_attr=Proteins%20and%20Enzymes">IL-11</a></td> <td><a href="/search?keywords=il-15&common_name=IL-15&category_attr=Proteins%20and%20Enzymes">IL-15</a> *</td> <td><a href="/search?keywords=il-21&common_name=IL-21&category_attr=Proteins%20and%20Enzymes">IL-21</a> *</td> <td><a href="/search?keywords=m-csf&common_name=M-CSF&category_attr=Proteins%20and%20Enzymes">M-CSF</a> *</td> </tr> <tr> <td><a href="/search?keywords=scf&common_name=SCF/c-kit%20Ligand&category_attr=Proteins%20and%20Enzymes">SCF/c-kit Ligand</a> *</td> <td><a href="/search?keywords=thrombopoietin&common_name=Thrombopoietin/Tpo&category_attr=Proteins%20and%20Enzymes">Thrombopoietin</a> *</td> <td><a href="/search?keywords=vegf&common_name=VEGF&category_attr=Proteins%20and%20Enzymes">VEGF</a>*</td> <td><a href="/search?keywords=wnt-3a&common_name=Wnt-3a&category_attr=Proteins%20and%20Enzymes">Wnt-3a</a> *</td> </tr> </tbody> </table></figure> <p>*<a href="/gmp-products/gmp-proteins">GMP-grade Proteins</a> are available for these molecules.</p></div> </div> </div> <div> <div class="paragraph paragraph--type--individual-button mb-4 paragraph--view-mode--default w-100"> <div class="row"> <div class="col"> <a href="/search?keywords=cytokinegrowthfact&category_attr=Proteins%20and%20Enzymes" class="btn btn-primary float-left" type="link" > Search for Other Cytokines for Hematopoietic Stem Cell Research </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h3>Assessment of the Bioactivity of R&D Systems Recombinant Human Thrombopoietin</h3></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/bioactivity-rnd-recombinant-human-thrombopoietin.png" alt="A. Assessment of the bioactivity of R&D Systems Recombinant Human Tpo and compared with two leading competitors’ Tpo proteins" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p><strong>R&D Systems Recombinant Human Thrombopoietin/Tpo Displays Higher Activity than Leading Competitors’ Thrombopoietin Proteins. </strong></p> <p>The bioactivity of R&D Systems <a href="/p/proteins-enzymes/recombinant-human-thrombopoietin-e-coli-expressed-cf_288-tpe">Recombinant Human Thrombopoietin</a> (Catalog # 288-TPE; orange line) or recombinant human Thrombopoietin/Tpo from two different competitors (green and purple lines) was assessed by measuring the ability of the proteins to stimulate proliferation of the MO7e human megakaryocytic leukemic cell line. The ED<sub>50</sub> for this effect for R&D Systems Recombinant Human Thrombopoietin is 0.05-0.5 ng/mL, which is over 2-fold more active than the two competitors’ proteins.</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h3>Consistency Testing of R&D Systems GMP-grade Recombinant Human Flt-3 L and SCF</h3></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/graphs/consistency-rnd-recombinant-human-flt-3l-scf.png" alt="Lot consistency and bioactivity of GMP and Animal-Free RUO Human Flt-3 Ligand" loading="lazy" > </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p><strong>R&D Systems GMP-grade Recombinant Human Flt-3 Ligand and GMP-grade Recombinant Human SCF Display High Lot-to-Lot Consistency.</strong></p> <p>A) Three independent lots of <a href="/p/proteins-enzymes/recombinant-human-flt-3-ligand-flt3l-gmp-protein-cf_308e-gmp">GMP-grade Recombinant Human Flt-3 Ligand</a> (R&D Systems, Catalog # 308E-GMP) were tested for their ability to stimulate proliferation of the BaF3 mouse pro-B cell line transfected with mouse Flt-3. The ED<sub>50</sub> for this effect is 0.2-1 ng/mL. (B) Three independent lots of <a href="/p/proteins-enzymes/recombinant-human-scf-gmp-protein-cf_bt-scf-gmp ">GMP-grade Recombinant Human SCF</a> (R&D Systems, Catalog # BT-SCF-GMP) were tested for their ability to stimulate proliferation of the TF-1 human erythroleukemic cell line. The ED<sub>50</sub> for this effect is 1-8 ng/mL. Each trace shown on the graphs represents data obtained from GMP-grade Recombinant Human Flt-3 Ligand or GMP-grade Recombinant Human SCF from a different manufacturing run to show the lot-to-lot consistency of the proteins.</p></div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <section class="paragraph paragraph--type--full-width-banner-with-image mb-4 paragraph--view-mode--default paragraph-background-color--dark"> <div class="banner_background_image" data-bgimage="https://resources.bio-techne.com/bio-techne-assets/images/banners/black-blue-pink-gradient-banner-1110x350.png" style="background-repeat: no-repeat;"> <div> <div> <div> <div class="paragraph paragraph--type--_-2-text-to-media mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_header_2_global"> <div><h2>New! Organoids Wall Poster</h2></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Organoids are emerging as powerful new platforms for exploring human organ development, modeling disease, screening for drug toxicity, and investigating personalized medicine. Request this poster to decorate your lab with some of the visually stunning organoid images that have been generated by 3-D cell culture specialists at Bio-Techne.</p></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_call_to_action_global"> <a href="/resources/literature/organoids-model-systems-of-tissue-development-and-disease-poster" class="btn btn-primary" type="link"> Request the Organoids Wall Poster </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_indv_media"> <div> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/obt-organoid-wall-poster-request-hero-v3.png" alt="Snapshot of the new organoid wall poster" loading="lazy" > </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><a name="otherstemcell"></a></p></div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <h2>Additional Stem Cell-Related Products</h2> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/research-areas/stem-cells" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/products-for-stem-cell-research-525x315.png" alt="Products for Stem Cell Research" loading="lazy" > </div> </a> <a class="card_title_link" href="/research-areas/stem-cells" > <h3 class="card_title_htag"> <div><h3>Products for Stem Cell Research</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Minimize variability in your stem cell experiments and ensure high performance by using our stem cell culture reagents. From isolation and culture to verification, reprogramming, differentiation, and characterization, we have products that you need for your stem cell research.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/research-areas/stem-cells" > Browse Our Collection of Stem Cell Reagents </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/cell-culture-reagents" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/cell-culture-reagents-525x315.png" alt="Cell Culture Reagents" loading="lazy" > </div> </a> <a class="card_title_link" href="/reagents/cell-culture-reagents" > <h3 class="card_title_htag"> <div><h3>Cell Culture Reagents </h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Browse our complete collection of products for cell culture. We offer a comprehensive range of reagents to promote robust cell growth, including media and supplements, basement membrane extracts, and custom cell culture services.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/cell-culture-reagents" > Learn More About Our Cell Culture Products </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/research-areas/organoids-3d-culture" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/organoid-3d-cell-culture-products-525x315.png" alt="Organoid and 3D cell culture products" loading="lazy" > </div> </a> <a class="card_title_link" href="/research-areas/organoids-3d-culture" > <h3 class="card_title_htag"> <div><h3>Organoid and 3-D Cell Culture Products </h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Optimize your organoid culture conditions by using our complete range of products designed to support robust, reproducible organoid expansion. We provide basement membrane extracts, growth factors, small molecules, media, and media supplements, along with antibodies and RNAscope™ <em>in situ</em> hybridization assays for identifying lineage-specific markers.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/research-areas/organoids-3d-culture" > Explore Our Organoid and 3-D Cell Culture Products </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/research-areas/regenerative-medicine" > <div class="teaser-card-image-crop mb-3"> <img loading="lazy" class="card-background-image card-img-top" src="https://resources.bio-techne.com/bio-techne-assets/images/banners/black-blue-gradient-525x315.png" /> </div> <div class="card-foreground-image"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/reg-med-products-200x200.png" alt="Products for Regenerative Medicine" loading="lazy" > </div> </a> <a class="card_title_link" href="/research-areas/regenerative-medicine" > <h3 class="card_title_htag"> <div><h3>Products for Regenerative Medicine</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Expand the frontiers in regenerative medicine with the power and flexibility of stem cells. We support regenerative medicine manufacturing with a vast array of products and services to help you advance and manufacture treatments for degenerative diseases, tissue injury, and genetic defects.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/research-areas/regenerative-medicine" > Learn More About Our Products for Regenerative Medicine </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/gmp-capabilities" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/gmp-capabilities-teaser-525x315.png" alt="GMP Capabilities" loading="lazy" > </div> </a> <a class="card_title_link" href="/gmp-capabilities" > <h3 class="card_title_htag"> <div><h3>GMP Capabilities</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>GMP ancillary and raw materials must provide robust performance in cell manufacturing workflows. With our focus on quality, innovation, supply chain continuity, and traceability, Bio-Techne GMP reagents are the reliable solution for your cell culture expansion and differentiation protocols.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/gmp-capabilities" > Learn More About Our GMP Capabilities </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/services/custom-cell-and-gene-therapy-services" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/custom-solutions-cgt-525x315.png" alt="Custom Solutions for Cell and Gene Therapy" loading="lazy" > </div> </a> <a class="card_title_link" href="/services/custom-cell-and-gene-therapy-services" > <h3 class="card_title_htag"> <div><h3>Custom Solutions for Cell and Gene Therapy</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Customization of raw materials enables cell therapy manufacturers to be confident in the security of their supply, reduces risks associated with manufacturing processes, and improves scalability. From GMP-grade proteins and antibodies to cell processing and custom chemistry services, we can develop the exact tools that you need for manufacturing your cell or gene therapy.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/services/custom-cell-and-gene-therapy-services" > Inquire About Custom Cell and Gene Therapy Services </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--button-row paragraph--view-mode--default"> <div class="row"> <div class="col"> <div><h3>Stem Cell-Related Resources</h3></div> <div class="list-grid-wrap"> <div class="row"> <div class="col-md-4"> <a href="https://www.rndsystems.com/resources/posters/unleash-potential-stem-cells" class="btn btn-primary" type="link"> Unleash the Potential of Stem Cells Poster </a> </div> <div class="col-md-4"> <a href="https://www.rndsystems.com/resources/literature/pioneering-cell-and-gene-therapy-solutions-discovery-clinic" class="btn btn-primary" type="link"> Cell and Gene Therapy Manufacturing Guide </a> </div> <div class="col-md-4"> <a href="https://www.rndsystems.com/resources/literature/embryonic-and-induced-pluripotent-stem-cells" class="btn btn-primary" type="link"> ESC and iPSC Workflow Solutions Guide </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--button-row paragraph--view-mode--default"> <div class="row"> <div class="col"> <div class="list-grid-wrap"> <div class="row"> <div class="col-md-4"> <a href="https://resources.rndsystems.com/images/site/rnd-systems-hsc-br2.pdf" class="btn btn-primary" type="link"> Hematopoietic Stem Cells Guide </a> </div> <div class="col-md-4"> <a href="https://resources.rndsystems.com/pdfs/brochures/rndsytems_br_nsc_mkt20-10864.pdf" class="btn btn-primary" type="link"> Neural Stem Cells Product Guide </a> </div> <div class="col-md-4"> <a href="/resources/literature/organoid-handbook" class="btn btn-primary" type="link"> Organoid Culture Handbook </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </article> </div> </div> </section> </main> </div> <div id="brandsbar-footer" class="bg-bt-primary"> <div class="container-wide container-fluid text-white"> <div class="row py-5"> <div class="footer-logo col-xl-3 col-lg-auto d-flex"> <img class="brand-bar-footer-logo" src="/themes/custom/bio_techne_global/logo.svg" alt="Bio-techne logo"> </div> <div class="col-xl-9 col-lg-auto"> <p class="ml-xl-4 bt-px_groteskbold footer-tagline">Global Developer, Manufacturer, and Supplier of High-Quality Reagents, Analytical Instruments, and Precision Diagnostics.</p> </div> <div class="included-brands col"> <span class="font-weight-bold mr-3 bt-inter_regular">INCLUDES</span> <span class="mr-3 bt-inter_regular">R&D Systems™</span> <span class="mr-3 bt-inter_regular">Novus Biologicals™</span> <span class="mr-3 bt-inter_regular">Tocris Bioscience™</span> <span class="mr-3 bt-inter_regular">ProteinSimple™</span> <span class="mr-3 bt-inter_regular">ACD™</span> <span class="mr-3 bt-inter_regular">ExosomeDx™</span> <span class="mr-3 bt-inter_regular">Asuragen™</span> <span class="mr-3 bt-inter_regular">Lunaphore™</span> </div> </div> </div> </div> <div id="site-footer__top" class=" pt-4"> <div class="container-wide container-fluid pt-3"> <div> <div class="col-md-12"> <footer> <div> <div class="row"> <div class="col-xl-3 col-md-6 col-xs-12 p-0 text-white bt-inter_regular"> <div> <div id="block-footercolumn1" class="block_content:8da4adc8-094f-4085-8706-613703de4da6"> <div><h4>CONTACT INFORMATION</h4> <p>614 McKinley Place NE<br /> Minneapolis, MN 55413<br /> USA</p> <p>TEL <a href="tel:612 379 2956">612 379 2956</a><br /> Toll-free <a href="tel:800 343 7475">800 343 7475</a><br /> FAX 612 656 4400</p> </div> </div> </div> </div> <div class="col-xl-3 col-md-6 col-xs-12 p-0 bt-inter_regular"> <div> <nav role="navigation" aria-labelledby="block-footercolumn2-menu" id="block-footercolumn2"> <h4 id="block-footercolumn2-menu">Who We Are</h4> <ul> <li> <a href="/about/about-bio-techne" title="About Bio-Techne" data-drupal-link-system-path="node/16">About Bio-Techne</a> </li> <li> <a href="/brands" title="Brands" data-drupal-link-system-path="node/46">Bio-Techne Brands</a> </li> <li> <a href="/about/careers" title="History" data-drupal-link-system-path="node/21">Careers </a> </li> <li> <a href="/about/corporate-and-social-responsibility" title="Corporate Responsibility" data-drupal-link-system-path="node/61">Corporate & Social Responsibility </a> </li> <li> <a href="/terms-and-conditions" data-drupal-link-system-path="node/686">Terms and Conditions</a> </li> </ul> </nav> </div> </div> <div class="col-xl-3 col-md-6 col-xs-12 p-0 bt-inter_regular"> <div> <nav role="navigation" aria-labelledby="block-footercolumn3-menu" id="block-footercolumn3"> <h4 id="block-footercolumn3-menu">Investor Relations</h4> <ul> <li> <a href="https://investors.bio-techne.com/">Overview</a> </li> <li> <a href="https://investors.bio-techne.com/news-events">News / Events</a> </li> <li> <a href="https://investors.bio-techne.com/company-information">Company Information</a> </li> <li> <a href="https://investors.bio-techne.com/financial-information">Financial Information</a> </li> <li> <a href="https://investors.bio-techne.com/stock-data">Stock Data</a> </li> <li> <a href="https://investors.bio-techne.com/sec-filings">SEC Filings</a> </li> <li> <a href="https://investors.bio-techne.com/corporate-governance">Corporate Governance</a> </li> </ul> </nav> </div> </div> <div class="col-xl-3 col-md-6 col-xs-12 p-0 text-white bt-inter_regular"> <div> <div id="block-stayconnectedblock" class="block_content:3f9f347f-6b53-40fd-8dfa-25f57854770b"> <div><h4>Stay Connected</h4> <section class="social-icons mb-3"> <a href="https://www.linkedin.com/company/bio-techne" class="text-white mr-2" aria-label="Follow Bio-techne on LinkedIn"><span class="icon-linkedin rounded-pill p-3"></span></a> <a href="https://www.instagram.com/bio_techne/" class="text-white mr-2" aria-label="Follow Bio-techne on Instagram"><span class="icon-instagram rounded-pill p-3"></span></a> <a href="https://twitter.com/biotechne" class="text-white mr-2" aria-label="Follow Bio-techne on X"><span class="icon-x rounded-pill p-3"></span></a> <a href="https://www.youtube.com/channel/UCCE68f793S1eyQM2E1BH0Bw?reload=9" class="text-white mr-2" aria-label="Bio-techne YouTube channel"><span class="icon-youtube rounded-pill p-3"></span></a> <a href="https://www.facebook.com/BioTechne/" class="text-white" aria-label="Follow Bio-techne on Facebook"><span class="icon-facebook rounded-pill p-3"></span></a> </section></div> </div> </div> <div> <a href="/support/contact-us" class="py-2 mt-3 mb-4 text-center font-weight-bold text-decoration-none text-white">Contact Us </a> </div> </div> </div> </div> </footer> </div> <hr> <div class="pb-5 mt-4 d-flex flex-wrap legal-navigation"> <div class="mb-2"> <a href="https://www.bio-techne.com/privacy-and-cookie-policy" class="mr-4 text-white text-center">Privacy and Cookie Policy</a> </div> <div class="mb-2"> <a href="/sitemap" class="mr-4 text-white">Site Map</a> </div> <div class="text-white">© Copyright 2024 Bio-Techne. All Rights Reserved.</div> </div> </div> </div> </div> </div> <div> <div id="block-cookieblock" class="cookie_block"> <div class="cookie-notification-block" data-expires="100"> <div class="container"> <div class="row pt-4 pb-4 pl-5 pr-5"> <div class="col-lg-10 mb-1"> Bio-Techne uses cookies to provide you with a great website experience. By continuing to use this website you acknowledge this and agree to our cookie policy. <a class="cookie-notification-block__link text-white" href="/privacy-and-cookie-policy">Learn more</a>. </div> <div class="col-lg-2 text-lg-right text-center align-middle"> <a href="#" class="btn btn-primary text-nowrap js-cookies"> I Agree </a> </div> </div> </div> </div> </div> </div> </div> <div class="embeddedServiceInvitation" id="snapins_invite" aria-live="assertive" role="dialog" aria-atomic="true" style="display: none;"> <div class="embeddedServiceInvitationHeader" aria-labelledby="snapins_titletext" aria-describedby="snapins_bodytext"> <img id="embeddedServiceAvatar"/> <span class="embeddedServiceTitleText" id="snapins_titletext">Need help?</span> <button type="button" id="closeInvite" class="embeddedServiceCloseIcon" aria-label="Exit invitation">×</button> </div> <div class="embeddedServiceInvitationBody"> <p id="snapins_bodytext">How can we help you?</p> </div> <div class="embeddedServiceInvitationFooter" aria-describedby="snapins_bodytext"> <button type="button" class="embeddedServiceActionButton" id="rejectInvite">Close</button> <button type="button" class="embeddedServiceActionButton" id="acceptInvite">Start Chat</button> </div> </div> <script>window.dataLayer = window.dataLayer || []; window.dataLayer.push({"drupalLanguage":"en","drupalCountry":"US","siteName":"Bio-Techne","brand":"R\u0026D","entityLangcode":"en","entityStatus":"1","entityType":"node","entityBundle":"hero_page","entityId":"1726","entityTitle":"Proteins for Stem Cell Research","userUid":0});</script> <script src="/sites/default/files/js/js_VCuLJxWfwcxc208bItHJBuLPq8DlU4ex_zmsx0pJbhk.js?scope=footer&delta=0&language=en&theme=bio_techne_global&include=eJxtUltywzAIvJCpjqRBMrFpsfAgnMQ5fRU_Mn3kR1oWZtGCEqtTHgtF4StFHKh4SCcJTxI2ssFkaGvXo6PgShYSjXhltdqRYHXOcUYf41LJIuasS_EaDgBGvliBuYk1qfLVtSbxaD2IJpSQVL264RxzX97k9wuqr01g6AbVQSg6DmHw6XeIw9_4Az_x3iWPVEYsmfpIWaeJLFNIDicLLxYqO924J6Br81-7V_mrYn9QS-gXUyzqfOGMzlrCzsFPDpJobr5FdTLCPMaZ7yThNVCYlzqStQp8rGE7DyyK_QFnlfXCIkeY2-SrcPUzbTpxpSMyvBzoRml-M9KJekZoy5naxuHa3GrXJPole6yElsewXzGhdVycrGxmUPhxOm3rtRUqCWXfTcIsmGlU6Z92_nV9vgg2T9tf4XJRm3a1JwE_iHPb37d_CXQ"></script> <script src="//resources.bio-techne.com/bio-techne-assets/css/bootstrap/js/bootstrap.bundle.min.js"></script> <script src="/sites/default/files/js/js_Y7jSJq-M3rJaHtFC8IxmKpPWDHPmB6jtjmwzMsh7m6M.js?scope=footer&delta=2&language=en&theme=bio_techne_global&include=eJxtUltywzAIvJCpjqRBMrFpsfAgnMQ5fRU_Mn3kR1oWZtGCEqtTHgtF4StFHKh4SCcJTxI2ssFkaGvXo6PgShYSjXhltdqRYHXOcUYf41LJIuasS_EaDgBGvliBuYk1qfLVtSbxaD2IJpSQVL264RxzX97k9wuqr01g6AbVQSg6DmHw6XeIw9_4Az_x3iWPVEYsmfpIWaeJLFNIDicLLxYqO924J6Br81-7V_mrYn9QS-gXUyzqfOGMzlrCzsFPDpJobr5FdTLCPMaZ7yThNVCYlzqStQp8rGE7DyyK_QFnlfXCIkeY2-SrcPUzbTpxpSMyvBzoRml-M9KJekZoy5naxuHa3GrXJPole6yElsewXzGhdVycrGxmUPhxOm3rtRUqCWXfTcIsmGlU6Z92_nV9vgg2T9tf4XJRm3a1JwE_iHPb37d_CXQ"></script> </body> </html>

CINXE.COM

Stem Cell Proteins and Cultures for Research | Bio-Techne