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id="btn"><span></span></span> </header> <div id="subtitle-box"> <h2 id="page-title"><img src="https://peptigrowth.com/wp-content/themes/peptigrowth/img/title-products.svg" alt="<span>PG-001</span>HGF Alternative Peptide (c-Met Agonist)"></h2> </div> <h3 class="h3-subtitle"><span>PG-001</span>HGF Alternative Peptide (c-Met Agonist)</h3> <section> <article id="products-resolve"> <h3>Fully-Chemically Synthesized Peptide with Activity<br /> Equivalent to HGF</h3> <p>PeptiGrowth succeeded in developing a peptide that has the same receptor activation ability and cell proliferation promotion ability as HGF. PG-001, an alternative peptide to HGF, induces dimerization of c-Met receptors and exerts biological activity, similar to activities of HGF.</p> <h4>Induces Dimerization of c-Met and Exerts Biological Activity similar to HGF</h4> <div class="box-2col-blue"> <div class="box-2col-blue-img"><img decoding="async" src="https://peptigrowth.com/wp-content/uploads/2022/09/img-pg-001-1-en.jpg" alt="Induces Dimerization of c-Met and Exerts Biological Activity similar to HGF"></div> <div class="box-2col-blue-img"><img decoding="async" src="https://peptigrowth.com/wp-content/uploads/2022/09/img-pg-001-2-en.jpg" alt="Induces Dimerization of c-Met and Exerts Biological Activity similar to HGF"></div> </p></div> <p class="text-notice">*This is for illustrative purpose.</p> </article> <div class="bg-gradient"> <article> <p>We conducted a functional comparison test between our HGF Alternative Peptide (PG-001) and commercially available recombinant HGF. From the results, PG-001 demonstrated properties that promote the phosphorylation of the c-Met receptor and the proliferation of HUVEC at the same level per molecule compared to recombinant HGF. Considering that the molecular weight of PG-001 is approximately 4.7 kDa, which is about 16 times smaller than that of recombinant HGF, on a mass concentration basis (ng/mL), PG-001 exhibits comparable activity at 1/16th of the concentration of recombinant HGF. </p> <div class="box-2col"> <div><img decoding="async" src="https://peptigrowth.com/wp-content/uploads/2023/12/fig_pg001_01_en.jpg" alt="c-Met phosphorylation (A431 cell)"></div> <div><img decoding="async" src="https://peptigrowth.com/wp-content/uploads/2023/12/fig_pg001_02_en.jpg" alt="HUVEC Proliferation"></div> </p></div> </article></div> <article id="products-resolve"> <h4>Applications Data</h4> <p>Professor Hideki Taniguchi at the Institute of Medical Science, University of Tokyo conducted proliferation and cloning tests of liver cells derived from induced pluripotent stem cells (iPS cells) using recombinant HGF or PG-001. As a result, it was confirmed that PG-001 has activity equivalent to HGF at the same level.</p> <div class="box-1col-blue"> <div class="box-1col-blue-img"><img decoding="async" src="https://peptigrowth.com/wp-content/uploads/2023/04/img-pg-001-app-01.jpg" alt="Applications Data"></div> </p></div> </article> <div class="bg-gradient"> <article> <h4>Stability Data ＆ Safety Data</h4> <p class="textcenter"><a href="https://peptigrowth.com/wp-content/uploads/2024/06/Application-Note_PG-001_Stability-test-result_EN.pdf">Stability Data in Serum Free Medium at 37℃</a><br /> <a href="https://peptigrowth.com/wp-content/uploads/2024/06/Residual_property_data_PG-001_EN.pdf">Residual Property data</a></p> </article></div> <article class="article-narrow"> <h4>PG-001 Product Overview</h4> <div class="table-alternate"> <table> <tr> <th>Formulation</th> <td>Lyophilized</td> </tr> <tr> <th>Storage Condition</th> <td>≦-20℃</td> <tr> <th>Purity</th> <td>≧95% (HPLC)</td> </tr> <tr> <th>Molecular Weight</th> <td>4825.39 (Acetate)</td> </tr> <tr> <th>Product Size<br />(Quantity equivalent to recombinant HGF)</th> <td>2, 5, 15µg per a glass vial<br />(Equivalent to recombinant HGF Approx. 32, 80, 240µg)</td> </tr> </table> <p><a href="https://peptigrowth.com/wp-content/uploads/2024/02/PG-001_2ug_information_sheet_v240119.pdf">Information sheet</a> </div> <ul class="link-products"> <li><a class="link-selected" href="https://peptigrowth.com/en/products/pg-001/">PG-001</a></li> <li><a href="https://peptigrowth.com/en/products/pg-002/">PG-002</a></li> <li><a href="https://peptigrowth.com/en/products/pg-003/">PG-003</a></li> <li><a href="https://peptigrowth.com/en/products/pg-004/">PG-004</a></li> <li><a href="https://peptigrowth.com/en/products/pg-005/">PG-005/PG-006</a></li> <li><a href="https://peptigrowth.com/en/products/pg-007/">PG-007</a></li> </ul> <ul class="link-products"> <li><a href="https://peptigrowth.com/en/products/pg-008/">PG-008</a></li> <li><a href="https://peptigrowth.com/en/products/pg-009/">PG-009</a></li> <li><a href="https://peptigrowth.com/en/products/pg-010/">PG-010</a></li> <li><a href="https://peptigrowth.com/en/products/pg-011/">PG-011</a></li> </ul> </article> <div class="bg-gradient"> <article class="article-narrow"> <h3>Sample Requests and Purchases of Our Products</h3><p>We offer our products worldwide through the following distributors. Please contact the relevant distributors depending on your region. Please note that currently, we offer all products except PG-009 through distributors. For inquiries regarding PG-009 and bulk orders, please contact us directly through <a href="https://peptigrowth.com/en/contact/">the inquiry form</a> on our website.</p> <p>Additionally, we provide 1 free sample per product to each organization/lab for our products currently on the market. Please fill out <a href="https://forms.office.com/r/RQYSzBfBYi">the Sample Request Form</a> to request free samples.</p> <h4>Distributor</h4> <div class="table-alternate"> <table> <tbody> <tr> <th>Scientist.com</th> <td><a href="https://app.scientist.com/inventory?q=&filters%5Bmanufacturer_name%5D%5B%5D=PeptiGrowth&filters%5Binventory_config_uuid%5D%5B%5D=b2c86b9f-e0eb-48b3-b138-66161a43f02c" target="_blank" rel="noopener">https://app.scientist.com/inventory?q=&filters%5Bmanufacturer_name%5D%5B%5D=PeptiGrowth&filters%5Binventory_config_uuid%5D%5B%5D=b2c86b9f-e0eb-48b3-b138-66161a43f02c</a></td> </tr> <tr> <th>Stratech</th> <td><a href="https://www.stratech.co.uk/" target="_blank" rel="noopener">https://www.stratech.co.uk/</a></td> </tr> <tr> <th>Genesee Scientific</th> <td><a href="https://geneseesci.com/" target="_blank" rel="noopener">https://geneseesci.com/</a></td> </tr> <tr> <th>Abacus dx</th> <td><a href="https://www.abacusdx.com/" target="_blank" rel="noopener">https://www.abacusdx.com/</a></td> </tr> <tr> <th>Labscoop</th> <td><a href="https://labscoop.com/us/en" target="_blank" rel="noopener">https://labscoop.com/us/en</a></td> </tr></tbody> </table> <p class="table-attention"></p> </div> <br /> </article> </p></div> </section> <section id="footer-address"> <article> <h2><img src="https://peptigrowth.com/wp-content/themes/peptigrowth/img/logo-gray.png" alt="PeptiGrowth Inc."></h2> <p>PeptiGrowth Inc.<br /> Nihonbashi Life Science Building 7, 9-10, Nihonbashi Horidomecho 1-chome, Chuo-ku, Tokyo 103-0012, Japan<br /> TEL +81-70-7789-3905</p> <p class="button"><a href="https://peptigrowth.com/en/contact/">CONTACT</a></p> </article> </section> <footer> <ul id="footer-menu"><li id="menu-item-234" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-home menu-item-234"><a href="https://peptigrowth.com/en/">HOME</a></li> <li id="menu-item-227" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-227"><a href="https://peptigrowth.com/en/business/">BUSINESS</a></li> <li id="menu-item-1280" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1280"><a href="https://peptigrowth.com/en/products/">Products</a></li> <li id="menu-item-228" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-228"><a href="https://peptigrowth.com/en/company/">COMPANY</a></li> <li id="menu-item-1366" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-1366"><a href="https://peptigrowth.com/en/quality/">QUALITY</a></li> <li id="menu-item-74" class="menu-item menu-item-type-post_type_archive menu-item-object-news menu-item-74"><a href="https://peptigrowth.com/en/news/">NEWS</a></li> <li id="menu-item-229" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-229"><a href="https://peptigrowth.com/en/events/">EVENTS</a></li> <li id="menu-item-937" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-937"><a href="https://peptigrowth.com/en/distributor/">DISTRIBUTOR</a></li> <li id="menu-item-1450" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-1450"><a href="https://forms.office.com/r/RQYSzBfBYi">SAMPLE</a></li> <li id="menu-item-230" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-230"><a href="https://peptigrowth.com/en/contact/">CONTACT</a></li> <li id="menu-item-233" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-233"><a href="https://peptigrowth.com/en/terms/">TERMS</a></li> <li id="menu-item-232" class="menu-item menu-item-type-post_type menu-item-object-page menu-item-232"><a href="https://peptigrowth.com/en/privacy/">PRIVACY</a></li> <li id="menu-item-135" class="menu-item menu-item-type-custom menu-item-object-custom menu-item-135"><a href="/">JAPANESE</a></li> </ul><p id="copyright">Copyright © PeptiGrowth Inc. 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