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(PDF) Bacterial Etiology and Antibiotic Sensitivity Patterns of Early-Late Onset Neonatal Sepsis among Newborns in Shiraz, Iran 2004-2007 | Mehdi Kalani - Academia.edu

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The goal ofthe present study was to determine the bacterial etiology andantibiotic sensitivity patterns of neonatal sepsis.Methods: This cross" /> <meta property="article:author" content="https://independent.academia.edu/KalaniMehdi" /> <meta name="description" content="Background: Neonatal sepsis is a major cause of mortalityand morbidity, especially in developing countries. The goal ofthe present study was to determine the bacterial etiology andantibiotic sensitivity patterns of neonatal sepsis.Methods: This cross" /> <title>(PDF) Bacterial Etiology and Antibiotic Sensitivity Patterns of Early-Late Onset Neonatal Sepsis among Newborns in Shiraz, Iran 2004-2007 | Mehdi Kalani - Academia.edu</title> <link rel="canonical" href="https://www.academia.edu/29203264/Bacterial_Etiology_and_Antibiotic_Sensitivity_Patterns_of_Early_Late_Onset_Neonatal_Sepsis_among_Newborns_in_Shiraz_Iran_2004_2007" /> <script async src="https://www.googletagmanager.com/gtag/js?id=G-5VKX33P2DS"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-5VKX33P2DS', { cookie_domain: 'academia.edu', send_page_view: false, }); gtag('event', 'page_view', { 'controller': "single_work", 'action': "show", 'controller_action': 'single_work#show', 'logged_in': 'false', 'edge': 'unknown', // Send nil if there is no A/B test bucket, in case some records get logged // with missing data - that way we can distinguish between the two cases. // ab_test_bucket should be of the form <ab_test_name>:<bucket> 'ab_test_bucket': null, }) </script> <script> var $controller_name = 'single_work'; var $action_name = "show"; var $rails_env = 'production'; var $app_rev = '49879c2402910372f4abc62630a427bbe033d190'; var $domain = 'academia.edu'; var $app_host = "academia.edu"; var $asset_host = "academia-assets.com"; var $start_time = new Date().getTime(); var $recaptcha_key = "6LdxlRMTAAAAADnu_zyLhLg0YF9uACwz78shpjJB"; var $recaptcha_invisible_key = "6Lf3KHUUAAAAACggoMpmGJdQDtiyrjVlvGJ6BbAj"; var $disableClientRecordHit = false; </script> <script> window.require = { config: function() { return function() {} } } </script> <script> window.Aedu = window.Aedu || {}; window.Aedu.hit_data = null; window.Aedu.serverRenderTime = new Date(1732510470000); window.Aedu.timeDifference = new Date().getTime() - 1732510470000; </script> <script type="application/ld+json">{"@context":"https://schema.org","@type":"ScholarlyArticle","abstract":"Background: Neonatal sepsis is a major cause of mortalityand morbidity, especially in developing countries. The goal ofthe present study was to determine the bacterial etiology andantibiotic sensitivity patterns of neonatal sepsis.Methods: This cross sectional study was conducted on 208neonates admitted with clinically suspected sepsis over a periodof 30 months. Sepsis was divided into early onset sepsis(EOS, ≤5 days of age) and late onset sepsis (LOS, \u0026amp;amp;gt;5 days ofage). The two groups were further divided into proven (culturepositive ± abnormal markers) and probable (culture negative +abnormal markers) subgroups. Blood culture was performedusing Bactec.Results: Of 208 cases, 90 had neonatal sepsis consisting of 38(26 proven) presented as EOS and 52 (42 proven) as LOS. In theEOS, Escherichia coli (E. coli) was the most common organismfollowed by klebsiella spp, Staphylococcus aureus (S. aureus).As for LOS, Coagulase-negative staphylococci (CONS) were themost common organism followed...","author":[{"@context":"https://schema.org","@type":"Person","name":"Mehdi Kalani"}],"contributor":[],"dateCreated":"2016-10-16","dateModified":"2016-10-16","datePublished":null,"headline":"Bacterial Etiology and Antibiotic Sensitivity Patterns of Early-Late Onset Neonatal Sepsis among Newborns in Shiraz, Iran 2004-2007","inLanguage":"en","keywords":[],"locationCreated":null,"publication":null,"publisher":{"@context":"https://schema.org","@type":"Organization","name":null},"image":null,"thumbnailUrl":null,"url":"https://www.academia.edu/29203264/Bacterial_Etiology_and_Antibiotic_Sensitivity_Patterns_of_Early_Late_Onset_Neonatal_Sepsis_among_Newborns_in_Shiraz_Iran_2004_2007","sourceOrganization":[{"@context":"https://schema.org","@type":"EducationalOrganization","name":null}]}</script><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/single_work_page/loswp-352e32ba4e89304dc0b4fa5b3952eef2198174c54cdb79066bc62e91c68a1a91.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/body-8d679e925718b5e8e4b18e9a4fab37f7eaa99e43386459376559080ac8f2856a.css" /><link rel="stylesheet" media="all" href="//a.academia-assets.com/assets/design_system/button-3cea6e0ad4715ed965c49bfb15dedfc632787b32ff6d8c3a474182b231146ab7.css" /><link 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"https://www.academia.edu/login?post_login_redirect_url=https%3A%2F%2Fwww.academia.edu%2F29203264%2FBacterial_Etiology_and_Antibiotic_Sensitivity_Patterns_of_Early_Late_Onset_Neonatal_Sepsis_among_Newborns_in_Shiraz_Iran_2004_2007%3Fshow_translation%3Dtrue"; window.loswp.previewableAttachments = [{"id":49653123,"identifier":"Attachment_49653123","shouldShowBulkDownload":false}]; window.loswp.shouldDetectTimezone = true; window.loswp.shouldShowBulkDownload = true; window.loswp.showSignupCaptcha = false window.loswp.willEdgeCache = false; window.loswp.work = {"work":{"id":29203264,"created_at":"2016-10-16T21:30:42.292-07:00","from_world_paper_id":158316749,"updated_at":"2021-01-16T10:02:09.857-08:00","_data":{"abstract":"Background: Neonatal sepsis is a major cause of mortalityand morbidity, especially in developing countries. The goal ofthe present study was to determine the bacterial etiology andantibiotic sensitivity patterns of neonatal sepsis.Methods: This cross sectional study was conducted on 208neonates admitted with clinically suspected sepsis over a periodof 30 months. Sepsis was divided into early onset sepsis(EOS, ≤5 days of age) and late onset sepsis (LOS, \u0026gt;5 days ofage). The two groups were further divided into proven (culturepositive ± abnormal markers) and probable (culture negative +abnormal markers) subgroups. Blood culture was performedusing Bactec.Results: Of 208 cases, 90 had neonatal sepsis consisting of 38(26 proven) presented as EOS and 52 (42 proven) as LOS. In theEOS, Escherichia coli (E. coli) was the most common organismfollowed by klebsiella spp, Staphylococcus aureus (S. aureus).As for LOS, Coagulase-negative staphylococci (CONS) were themost common organism followed..."},"document_type":"paper","pre_hit_view_count_baseline":null,"quality":"high","language":"en","title":"Bacterial Etiology and Antibiotic Sensitivity Patterns of Early-Late Onset Neonatal Sepsis among Newborns in Shiraz, Iran 2004-2007","broadcastable":true,"draft":null,"has_indexable_attachment":true,"indexable":true}}["work"]; window.loswp.workCoauthors = [54457224]; window.loswp.locale = "en"; window.loswp.countryCode = "SG"; window.loswp.cwvAbTestBucket = ""; window.loswp.designVariant = "ds_vanilla"; window.loswp.fullPageMobileSutdModalVariant = "control"; window.loswp.useOptimizedScribd4genScript = false; window.loswp.appleClientId = 'edu.academia.applesignon';</script><script defer="" src="https://accounts.google.com/gsi/client"></script><div class="ds-loswp-container"><div class="ds-work-card--grid-container"><div class="ds-work-card--container js-loswp-work-card"><div class="ds-work-card--cover"><div class="ds-work-cover--wrapper"><div class="ds-work-cover--container"><button class="ds-work-cover--clickable js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;swp-splash-paper-cover&quot;,&quot;attachmentId&quot;:49653123,&quot;attachmentType&quot;:&quot;pdf&quot;}"><img alt="First page of “Bacterial Etiology and Antibiotic Sensitivity Patterns of Early-Late Onset Neonatal Sepsis among Newborns in Shiraz, Iran 2004-2007”" class="ds-work-cover--cover-thumbnail" src="https://0.academia-photos.com/attachment_thumbnails/49653123/mini_magick20190130-782-1dp0mcz.png?1548916145" /><img alt="PDF Icon" class="ds-work-cover--file-icon" src="//a.academia-assets.com/assets/single_work_splash/adobe.icon-574afd46eb6b03a77a153a647fb47e30546f9215c0ee6a25df597a779717f9ef.svg" /><div class="ds-work-cover--hover-container"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span><p>Download Free PDF</p></div><div class="ds-work-cover--ribbon-container">Download Free PDF</div><div class="ds-work-cover--ribbon-triangle"></div></button></div></div></div><div class="ds-work-card--work-information"><h1 class="ds-work-card--work-title">Bacterial Etiology and Antibiotic Sensitivity Patterns of Early-Late Onset Neonatal Sepsis among Newborns in Shiraz, Iran 2004-2007</h1><div class="ds-work-card--work-authors ds-work-card--detail"><a class="ds-work-card--author js-wsj-grid-card-author ds2-5-body-md ds2-5-body-link" data-author-id="54457224" href="https://independent.academia.edu/KalaniMehdi"><img alt="Profile image of Mehdi Kalani" class="ds-work-card--author-avatar" src="//a.academia-assets.com/images/s65_no_pic.png" />Mehdi Kalani</a></div><p class="ds-work-card--work-abstract ds-work-card--detail ds2-5-body-md">Background: Neonatal sepsis is a major cause of mortalityand morbidity, especially in developing countries. The goal ofthe present study was to determine the bacterial etiology andantibiotic sensitivity patterns of neonatal sepsis.Methods: This cross sectional study was conducted on 208neonates admitted with clinically suspected sepsis over a periodof 30 months. Sepsis was divided into early onset sepsis(EOS, ≤5 days of age) and late onset sepsis (LOS, &amp;gt;5 days ofage). The two groups were further divided into proven (culturepositive ± abnormal markers) and probable (culture negative +abnormal markers) subgroups. Blood culture was performedusing Bactec.Results: Of 208 cases, 90 had neonatal sepsis consisting of 38(26 proven) presented as EOS and 52 (42 proven) as LOS. In theEOS, Escherichia coli (E. coli) was the most common organismfollowed by klebsiella spp, Staphylococcus aureus (S. aureus).As for LOS, Coagulase-negative staphylococci (CONS) were themost common organism followed...</p><div class="ds-work-card--button-container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--work-card&quot;,&quot;attachmentId&quot;:49653123,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:&quot;https://www.academia.edu/29203264/Bacterial_Etiology_and_Antibiotic_Sensitivity_Patterns_of_Early_Late_Onset_Neonatal_Sepsis_among_Newborns_in_Shiraz_Iran_2004_2007&quot;}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--work-card&quot;,&quot;attachmentId&quot;:49653123,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:&quot;https://www.academia.edu/29203264/Bacterial_Etiology_and_Antibiotic_Sensitivity_Patterns_of_Early_Late_Onset_Neonatal_Sepsis_among_Newborns_in_Shiraz_Iran_2004_2007&quot;}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div></div><div data-auto_select="false" data-client_id="331998490334-rsn3chp12mbkiqhl6e7lu2q0mlbu0f1b" data-doc_id="49653123" data-landing_url="https://www.academia.edu/29203264/Bacterial_Etiology_and_Antibiotic_Sensitivity_Patterns_of_Early_Late_Onset_Neonatal_Sepsis_among_Newborns_in_Shiraz_Iran_2004_2007" data-login_uri="https://www.academia.edu/registrations/google_one_tap" data-moment_callback="onGoogleOneTapEvent" id="g_id_onload"></div><div class="ds-top-related-works--grid-container"><div class="ds-related-content--container ds-top-related-works--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="0" data-entity-id="86523103" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/86523103/Study_on_Bacteriological_Profile_and_Sensitivity_Pattern_of_the_Organisms_in_Neonatal_Sepsis">Study on Bacteriological Profile and Sensitivity Pattern of the Organisms in Neonatal Sepsis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="113185050" href="https://independent.academia.edu/SubirDey7">Subir Dey</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2021</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: Sepsis in neonates by resistant strains remains a significant cause of mortality and morbidity in developing countries. This study attempted to find out the organisms responsible for early onset sepsis (EOS) and late onset sepsis (LOS) and determine their antimicrobial sensitivity pattern. Materials &amp; Methods: This prospective observational single centre study was conducted on 1000 neonates during January to September 2018, that were investigated for rule out sepsis, at the Neonatal Intensive Care Unit of Ad-din Medical College Hospital, Dhaka. Results: Fifty-four neonates were found with culture proven sepsis.Coagulase-negative Staphylococci (CONS) (68.42%)was the commonest and followed by Acinetobacter (18.42%) were found on culture isolates in EOS. In LOS, CONS (75%) is the most predominant organism. Among the gram negative Acinetobacter (50%) was the most prevalent bacteria followed by E.coli (28.57%). None of the gram positive isolates were sensitive to Amikacin. Ma...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Study on Bacteriological Profile and Sensitivity Pattern of the Organisms in Neonatal Sepsis&quot;,&quot;attachmentId&quot;:90955623,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/86523103/Study_on_Bacteriological_Profile_and_Sensitivity_Pattern_of_the_Organisms_in_Neonatal_Sepsis&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/86523103/Study_on_Bacteriological_Profile_and_Sensitivity_Pattern_of_the_Organisms_in_Neonatal_Sepsis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="1" data-entity-id="26699231" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26699231/Identification_of_bacterial_agents_and_antimicrobial_susceptibility_of_neonatal_sepsis_A_54_month_study_in_a_tertiary_hospital">Identification of bacterial agents and antimicrobial susceptibility of neonatal sepsis: A 54-month study in a tertiary hospital</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="50693053" href="https://independent.academia.edu/MohammadAletayeb">Mohammad Aletayeb</a></div><p class="ds-related-work--metadata ds2-5-body-xs">African journal of microbiology research</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Identification of bacterial agents and antimicrobial susceptibility of neonatal sepsis: A 54-month study in a tertiary hospital&quot;,&quot;attachmentId&quot;:46981166,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/26699231/Identification_of_bacterial_agents_and_antimicrobial_susceptibility_of_neonatal_sepsis_A_54_month_study_in_a_tertiary_hospital&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/26699231/Identification_of_bacterial_agents_and_antimicrobial_susceptibility_of_neonatal_sepsis_A_54_month_study_in_a_tertiary_hospital"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="2" data-entity-id="89161738" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/89161738/Neonatal_Sepsis_1991_2001_Prevalent_Bacterial_Agents_and_Antimicrobial_Susceptibilities_in_Bahrain">Neonatal Sepsis 1991–2001: Prevalent Bacterial Agents and Antimicrobial Susceptibilities in Bahrain</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="910271" href="https://uniud.academia.edu/GiuseppeBotta">Giuseppe Botta</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Medical Principles and Practice, 2006</p><p class="ds-related-work--abstract ds2-5-body-sm">Objectives: To investigate the organisms causing neonatal sepsis and their modifications over an extended period, to assess their changing sensitivities to antibiotics and to verify whether the policy for screening pregnant women for group B streptococci (GBS) carriage is desirable in our settings. Subjects and Methods: Medical records of all infants with positive blood culture from the Neonatal Intensive Care Unit at Salmaniya Medical Complex between 1991 and 2001 and Bahrain Defense Force Hospital between 1999 and 2001 were reviewed. Results: Of the 7,978 neonates in both hospitals 335 (4.19%) had culture-proven bacteremia. Gram-positive bacteria were isolated at constant rate over the 11-year period. The main agents isolated were coagulase-negative Staphylococcus (CoNS) in 138 cases (41%), Staphylococcus aureus in 28 newborns (8%) and GBS in 26 patients (7.8%, 0.2/1,000 live births). All of them were sensitive to penicillin G, erythromycin and clindamycin. Gram-negative bacteria ...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal Sepsis 1991–2001: Prevalent Bacterial Agents and Antimicrobial Susceptibilities in Bahrain&quot;,&quot;attachmentId&quot;:93011866,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/89161738/Neonatal_Sepsis_1991_2001_Prevalent_Bacterial_Agents_and_Antimicrobial_Susceptibilities_in_Bahrain&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/89161738/Neonatal_Sepsis_1991_2001_Prevalent_Bacterial_Agents_and_Antimicrobial_Susceptibilities_in_Bahrain"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="3" data-entity-id="31781770" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/31781770/Neonatal_Sepsis_Bacteria_and_their_Susceptibility_Pattern_towards_Antibiotics_in_Neonatal_Intensive_Care_Unit">Neonatal Sepsis&quot;: Bacteria &amp; their Susceptibility Pattern towards Antibiotics in Neonatal Intensive Care Unit</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58496371" href="https://friends.academia.edu/deeptisharma">deepti sharma</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of clinical and diagnostic research : JCDR, 2013</p><p class="ds-related-work--abstract ds2-5-body-sm">Neonatal sepsis is one of the most common causes of neonatal mortality and morbidity, particularly in the developing countries. Its causative bacteria and their respective sensitivity patterns are different in each hospital and region. The objective of this study was to determine the causative bacteria and pattern of susceptibility to antibiotics in NICU of a tertiary care centre, which in turn may help in implementation of empirical therapy. This prospective study was carried out at a medical college during the period from 1st April 2011 to 31st March 2013. A total of 364 cases of suspected sepsis were admitted in our NICU during the mentioned period. Out of which, 137 cases were positive for culture. All the neonates of suspected sepsis were screened by using a panel consisting of CRP, ANC, I/T ratio, micro ESR and culture and sensitivity. A total of 137 cultures were found to be positive out of 364 cases. The most common organism isolated was Staphylococcus aureus (37.22%) follow...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal Sepsis\&quot;: Bacteria \u0026 their Susceptibility Pattern towards Antibiotics in Neonatal Intensive Care Unit&quot;,&quot;attachmentId&quot;:52083702,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/31781770/Neonatal_Sepsis_Bacteria_and_their_Susceptibility_Pattern_towards_Antibiotics_in_Neonatal_Intensive_Care_Unit&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/31781770/Neonatal_Sepsis_Bacteria_and_their_Susceptibility_Pattern_towards_Antibiotics_in_Neonatal_Intensive_Care_Unit"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="4" data-entity-id="99081935" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/99081935/Neonatal_Sepsis_A_Study_on_Isolated_Pathogens_and_Their_Susceptibility_Pattern_at_Tertiary_Care_Hospital_in_Rural_Setting">Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="81067189" href="https://independent.academia.edu/NagaSriLathaBathala">Naga Sri Latha Bathala</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal Sepsis: A Study on Isolated Pathogens and Their Susceptibility Pattern at Tertiary Care Hospital in Rural Setting&quot;,&quot;attachmentId&quot;:100263439,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/99081935/Neonatal_Sepsis_A_Study_on_Isolated_Pathogens_and_Their_Susceptibility_Pattern_at_Tertiary_Care_Hospital_in_Rural_Setting&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/99081935/Neonatal_Sepsis_A_Study_on_Isolated_Pathogens_and_Their_Susceptibility_Pattern_at_Tertiary_Care_Hospital_in_Rural_Setting"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="5" data-entity-id="101275033" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/101275033/Bacteriological_Profile_and_Antibiotic_Susceptibility_Pattern_of_Isolates_in_Neonatal_Sepsis">Bacteriological Profile and Antibiotic Susceptibility Pattern of Isolates in Neonatal Sepsis</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="268415953" href="https://independent.academia.edu/ShaistaEhsan">Shaista Ehsan</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Pakistan Journal of Health Sciences</p><p class="ds-related-work--abstract ds2-5-body-sm">Sepsis in newborns is a serious medical condition having a high mortality. Pakistan and other developing countries have a high burden of neonatal sepsis. Objectives: To determine the bacterial spectrum and antibiotic activity pattern in neonatal sepsis. Methods: This retrospective cross-sectional research was performed at the Pediatrics Unit of Ziauddin University Hospital Karachi from 1st June 2022 till 1st December 2022. A total of 120 medical records of neonates admitted with the clinical suspicion of sepsis were reviewed. Non-probability convenience sampling technique was used. Data regarding clinical characteristics of neonates, type of bacteria isolated and antibiotic susceptibility results were recorded. SPSS version 20 was used for statistical analysis. The results were written as frequencies / percentages. Results: Neonatal sepsis was suspected in 120 newborns but blood culture-proven infection was present in 32 (13.3%) neonates with 23(71.8%) having early -onset sepsis. T...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Bacteriological Profile and Antibiotic Susceptibility Pattern of Isolates in Neonatal Sepsis&quot;,&quot;attachmentId&quot;:101861251,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/101275033/Bacteriological_Profile_and_Antibiotic_Susceptibility_Pattern_of_Isolates_in_Neonatal_Sepsis&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/101275033/Bacteriological_Profile_and_Antibiotic_Susceptibility_Pattern_of_Isolates_in_Neonatal_Sepsis"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="6" data-entity-id="79564114" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/79564114/Neonatal_sepsis_in_southwest_of_Iran_prevalence_of_microbial_pathogens_risk_factors_clinical_manifestations_and_laboratory_findings">Neonatal sepsis in southwest of Iran; prevalence of microbial pathogens, risk factors, clinical manifestations and laboratory findings</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="39311957" href="https://yasujmedicalsciences.academia.edu/AliMousavizadeh">Ali Mousavizadeh</a></div><p class="ds-related-work--metadata ds2-5-body-xs">2020</p><p class="ds-related-work--abstract ds2-5-body-sm">Background: Neonatal sepsis is a serious worldwide problem causing significant rates of mortality and morbidity in newborns, especially in cases with delayed infection diagnosis and management. The present study aimed to evaluate the bacteriological profiles, antibiotic susceptibility patterns, risk factors, clinical manifestations, and laboratory findings in neonatal sepsis in southwest of Iran. Methods: In this descriptive-analytic study, 342 neonates with suspected sepsis admitted to the neonatal ward and NICU were included. Using standard protocols, blood samples were transported to the BACTEC blood culture system. Then, conventional biochemical tests were used for the identification of bacterial genera and species. The bacterial antimicrobial susceptibility patterns were determined usingagardisk diffusion method according to the CLSI guidelines. Demographic data, clinical findings, risk factors, mortality rates, and laboratory parameters were collected for each patient. Results...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Neonatal sepsis in southwest of Iran; prevalence of microbial pathogens, risk factors, clinical manifestations and laboratory findings&quot;,&quot;attachmentId&quot;:86236218,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/79564114/Neonatal_sepsis_in_southwest_of_Iran_prevalence_of_microbial_pathogens_risk_factors_clinical_manifestations_and_laboratory_findings&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/79564114/Neonatal_sepsis_in_southwest_of_Iran_prevalence_of_microbial_pathogens_risk_factors_clinical_manifestations_and_laboratory_findings"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="7" data-entity-id="58383268" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/58383268/Types_of_Bacteria_Associated_with_Neonatal_Sepsis_in_Al_Thawra_University_Hospital_Sana_a_Yemen_and_their_Antimicrobial_Profile">Types of Bacteria Associated with Neonatal Sepsis in Al-Thawra University Hospital , Sana’a , Yemen , and their Antimicrobial Profile</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="43582546" href="https://independent.academia.edu/HassanAlshamahy">Hassan A Al-Shamahy</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Sultan Qaboos University Medical Journal, 2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Types of Bacteria Associated with Neonatal Sepsis in Al-Thawra University Hospital , Sana’a , Yemen , and their Antimicrobial Profile&quot;,&quot;attachmentId&quot;:72821212,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/58383268/Types_of_Bacteria_Associated_with_Neonatal_Sepsis_in_Al_Thawra_University_Hospital_Sana_a_Yemen_and_their_Antimicrobial_Profile&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/58383268/Types_of_Bacteria_Associated_with_Neonatal_Sepsis_in_Al_Thawra_University_Hospital_Sana_a_Yemen_and_their_Antimicrobial_Profile"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="8" data-entity-id="65421117" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/65421117/Bacteriological_Profile_of_Neonatal_Sepsis_A_Hospital_Based_Study">Bacteriological Profile of Neonatal Sepsis: A Hospital Based Study</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="207878542" href="https://independent.academia.edu/NabinShrestha88">Nabin Shrestha</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of Nepal Paediatric Society, 2011</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Bacteriological Profile of Neonatal Sepsis: A Hospital Based Study&quot;,&quot;attachmentId&quot;:77026237,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/65421117/Bacteriological_Profile_of_Neonatal_Sepsis_A_Hospital_Based_Study&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/65421117/Bacteriological_Profile_of_Neonatal_Sepsis_A_Hospital_Based_Study"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div><div class="ds-related-work--container js-wsj-grid-card" data-collection-position="9" data-entity-id="75368788" data-sort-order="default"><a class="ds-related-work--title js-wsj-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/75368788/Bacterial_Causative_Agents_of_Neonatal_Sepsis_and_Their_Antibiotic_Susceptibility_in_Neonatal_Intensive_Care_Units_NICUs_and_Neonatal_Wards_in_Iran_A_Systematic_Review">Bacterial Causative Agents of Neonatal Sepsis and Their Antibiotic Susceptibility in Neonatal Intensive Care Units (NICUs) and Neonatal Wards in Iran: A Systematic Review</a><div class="ds-related-work--metadata"><a class="js-wsj-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="63351729" href="https://independent.academia.edu/Royalorestani">Roya lorestani</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Archives of Pediatric Infectious Diseases</p><p class="ds-related-work--abstract ds2-5-body-sm">Context: Sepsis is one of the most common causes of neonatal mortality, especially in developing countries. The purpose of this study was to systematically review the bacterial causative agents of neonatal sepsis and their antibiotic susceptibility in Iran. Material and Methods: We searched all previously published papers to gather related information on Iranian neonatal sepsis in international and national databases (in both Persian and English) from 2006 to 2018. The standard STROBE checklist was used for quality assessment. The data were analyzed by statistical methods with a random-effects model using Stata 14 software. Results: A total of 89,472 neonates with sepsis (presented in 17 studies) were included in this systematic review. The mortality rate of neonates was 28.0%. The proportions of neonatal sepsis caused by Gram-negative and Gram-positive bacteria were 66.0% and 33.0%, respectively. The most common bacteria causing neonatal sepsis were Klebsiella pneumoniae and Pseudo...</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Bacterial Causative Agents of Neonatal Sepsis and Their Antibiotic Susceptibility in Neonatal Intensive Care Units (NICUs) and Neonatal Wards in Iran: A Systematic Review&quot;,&quot;attachmentId&quot;:83164963,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;work_url&quot;:&quot;https://www.academia.edu/75368788/Bacterial_Causative_Agents_of_Neonatal_Sepsis_and_Their_Antibiotic_Susceptibility_in_Neonatal_Intensive_Care_Units_NICUs_and_Neonatal_Wards_in_Iran_A_Systematic_Review&quot;,&quot;alternativeTracking&quot;:true}"><span class="material-symbols-outlined" style="font-size: 18px" translate="no">download</span><span class="ds2-5-text-link__content">Download free PDF</span></button><a class="ds2-5-text-link ds2-5-text-link--inline js-wsj-grid-card-view-pdf" href="https://www.academia.edu/75368788/Bacterial_Causative_Agents_of_Neonatal_Sepsis_and_Their_Antibiotic_Susceptibility_in_Neonatal_Intensive_Care_Units_NICUs_and_Neonatal_Wards_in_Iran_A_Systematic_Review"><span class="ds2-5-text-link__content">View PDF</span><span class="material-symbols-outlined" style="font-size: 18px" translate="no">chevron_right</span></a></div></div></div></div><div class="ds-sticky-ctas--wrapper js-loswp-sticky-ctas hidden"><div class="ds-sticky-ctas--grid-container"><div class="ds-sticky-ctas--container"><button class="ds2-5-button js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;continue-reading-button--sticky-ctas&quot;,&quot;attachmentId&quot;:49653123,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}">See full PDF</button><button class="ds2-5-button ds2-5-button--secondary js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;download-pdf-button--sticky-ctas&quot;,&quot;attachmentId&quot;:49653123,&quot;attachmentType&quot;:&quot;pdf&quot;,&quot;workUrl&quot;:null}"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">download</span>Download PDF</button></div></div></div><div class="ds-below-fold--grid-container"><div class="ds-work--container js-loswp-embedded-document"><div class="attachment_preview" data-attachment="Attachment_49653123" style="display: none"><div class="js-scribd-document-container"><div class="scribd--document-loading js-scribd-document-loader" style="display: block;"><img alt="Loading..." src="//a.academia-assets.com/images/loaders/paper-load.gif" /><p>Loading Preview</p></div></div><div style="text-align: center;"><div class="scribd--no-preview-alert js-preview-unavailable"><p>Sorry, preview is currently unavailable. You can download the paper by clicking the button above.</p></div></div></div></div><div class="ds-sidebar--container js-work-sidebar"><div class="ds-related-content--container"><h2 class="ds-related-content--heading">Related papers</h2><div class="ds-related-work--container js-related-work-sidebar-card" data-collection-position="0" data-entity-id="30487495" data-sort-order="default"><a class="ds-related-work--title js-related-work-grid-card-title ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/30487495/Epidemiology_of_Neonatal_Sepsis_and_Implicated_Pathogens_A_Study_from_Egypt">Epidemiology of Neonatal Sepsis and Implicated Pathogens: A Study from Egypt</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="58113016" href="https://independent.academia.edu/MohammedSamyAfifi">Mohammed-Samy Afifi</a></div><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline 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ds2-5-body-md ds2-5-body-link" href="https://www.academia.edu/26154077/Trends_in_incidence_of_neonatal_sepsis_and_antibiotic_susceptibility_of_causative_agents_in_two_neonatal_intensive_care_units_in_tehran_I_R_iran">Trends in incidence of neonatal sepsis and antibiotic susceptibility of causative agents in two neonatal intensive care units in tehran, I.R iran</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="49922876" href="https://independent.academia.edu/aminsaburi">amin saburi</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Journal of clinical neonatology, 2012</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Trends in incidence of neonatal sepsis and antibiotic susceptibility of causative agents in two 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href="https://www.academia.edu/121922435/Epidemiology_of_Neonatal_Sepsis_and_Associated_Factors_Implicated_Observational_Study_at_Neonatal_Intensive_Care_Unit_of_Arsi_University_Teaching_and_Referral_Hospital_South_East_Ethiopia">Epidemiology of Neonatal Sepsis and Associated Factors Implicated: Observational Study at Neonatal Intensive Care Unit of Arsi University Teaching and Referral Hospital, South East Ethiopia</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="119127350" href="https://independent.academia.edu/ASorsa">Abebe Sorsa</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Ethiopian journal of health sciences, 1970</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Epidemiology of Neonatal Sepsis and 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Neonatal sepsis in a Nigerian private tertiary hospital: Bacterial isolates, risk factors, and antibiotic susceptibility patterns. Ann Afr Med 2017;16:52-8</a><div class="ds-related-work--metadata"><a class="js-related-work-grid-card-author ds2-5-body-sm ds2-5-body-link" data-author-id="262969660" href="https://independent.academia.edu/LawalUmar25">Lawal Umar</a></div><p class="ds-related-work--metadata ds2-5-body-xs">Annals of African medicine</p><div class="ds-related-work--ctas"><button class="ds2-5-text-link ds2-5-text-link--inline js-swp-download-button" data-signup-modal="{&quot;location&quot;:&quot;wsj-grid-card-download-pdf-modal&quot;,&quot;work_title&quot;:&quot;Shobowale EO, Solarin AU, Elikwu CJ, Onyedibe KI, Akinola IJ, Faniran AA. Neonatal sepsis in a Nigerian private tertiary hospital: Bacterial isolates, risk factors, and antibiotic susceptibility patterns. 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