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for most readers to understand</b>.<span class="hide-when-compact"> Please <a class="external text" href="https://en.wikipedia.org/w/index.php?title=Malignant_rhabdoid_tumour&action=edit">help improve it</a> to <a href="/wiki/Wikipedia:Make_technical_articles_understandable" title="Wikipedia:Make technical articles understandable">make it understandable to non-experts</a>, without removing the technical details.</span> <span class="date-container"><i>(<span class="date">April 2019</span>)</i></span><span class="hide-when-compact"><i> (<small><a href="/wiki/Help:Maintenance_template_removal" title="Help:Maintenance template removal">Learn how and when to remove this message</a></small>)</i></span></div></td></tr></tbody></table> <div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Medical condition</div><style data-mw-deduplicate="TemplateStyles:r1257001546">.mw-parser-output .infobox-subbox{padding:0;border:none;margin:-3px;width:auto;min-width:100%;font-size:100%;clear:none;float:none;background-color:transparent}.mw-parser-output .infobox-3cols-child{margin:auto}.mw-parser-output .infobox .navbar{font-size:100%}@media screen{html.skin-theme-clientpref-night .mw-parser-output .infobox-full-data:not(.notheme)>div:not(.notheme)[style]{background:#1f1f23!important;color:#f8f9fa}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .infobox-full-data:not(.notheme) div:not(.notheme){background:#1f1f23!important;color:#f8f9fa}}@media(min-width:640px){body.skin--responsive .mw-parser-output .infobox-table{display:table!important}body.skin--responsive .mw-parser-output .infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox ib-medical-condition"><tbody><tr><th colspan="2" class="infobox-above" style="background:#ccc">Malignant rhabdoid tumour</th></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Medical_specialty" title="Medical specialty">Specialty</a></th><td class="infobox-data"><a href="/wiki/Oncology" title="Oncology">Oncology</a> <span class="penicon autoconfirmed-show"><span class="mw-valign-text-top" typeof="mw:File/Frameless"><a href="https://www.wikidata.org/wiki/Q6743515?uselang=en#P1995" title="Edit this on Wikidata"><img alt="Edit this on Wikidata" src="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/10px-OOjs_UI_icon_edit-ltr-progressive.svg.png" decoding="async" width="10" height="10" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/15px-OOjs_UI_icon_edit-ltr-progressive.svg.png 1.5x, //upload.wikimedia.org/wikipedia/en/thumb/8/8a/OOjs_UI_icon_edit-ltr-progressive.svg/20px-OOjs_UI_icon_edit-ltr-progressive.svg.png 2x" data-file-width="20" data-file-height="20" /></a></span></span></td></tr></tbody></table> <p><b>Malignant rhabdoid tumour</b> (MRT) is a very aggressive form of <a href="/wiki/Tumor" class="mw-redirect" title="Tumor">tumour</a> originally described as a variant of <a href="/wiki/Wilms%27_tumor" title="Wilms' tumor">Wilms' tumour</a>, which is primarily a <a href="/wiki/Kidney_tumour" title="Kidney tumour">kidney tumour</a> that occurs mainly in children. </p><p>MRT was first described as a variant of Wilms' tumour of the kidney in 1978.<sup id="cite_ref-pmid206343_1-0" class="reference"><a href="#cite_note-pmid206343-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup> MRTs are a rare and highly malignant childhood <a href="/wiki/Neoplasm" title="Neoplasm">neoplasm</a>. Rhabdoid tumours outside the kidney were later reported in many tissues including the liver, soft tissue, and the <a href="/wiki/Central_nervous_system" title="Central nervous system">central nervous system</a> (CNS). Several cases of <a href="/wiki/Primary_tumor" title="Primary tumor">primary</a> <a href="/wiki/Intracranial" class="mw-redirect" title="Intracranial">intracranial</a> MRT have been reported since its recognition as a separate entity in 1978. The term <i>rhabdoid</i> was used due to its similarity with <a href="/wiki/Rhabdomyosarcoma" title="Rhabdomyosarcoma">rhabdomyosarcoma</a> under the <a href="/wiki/Light_microscope" class="mw-redirect" title="Light microscope">light microscope</a>. The exact <a href="/wiki/Pathogenesis" title="Pathogenesis">pathogenesis</a> of MRT is unknown. </p><p>The <a href="/wiki/Cerebellum" title="Cerebellum">cerebellum</a> is the most common location for primary intracerebral MRT (i.e., <a href="/wiki/Atypical_teratoid_rhabdoid_tumor" title="Atypical teratoid rhabdoid tumor">atypical teratoid rhabdoid tumor</a>). Biggs <i>et al.</i> were first to report a primary intracranial MRT around 1987.<sup id="cite_ref-2" class="reference"><a href="#cite_note-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> </p><p>Although the cell of origin is not known, <a href="/wiki/Cytogenetics" title="Cytogenetics">cytogenetic studies</a> have suggested a common genetic basis for rhabdoid tumours regardless of location with abnormalities in <a href="/wiki/Chromosome_22" title="Chromosome 22">chromosome 22</a> commonly occurring. </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Genetics">Genetics</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=1" title="Edit section: Genetics"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>There have been reported cases of a child having both atypical teratoid rhabdoid tumours in the brain as well as rhabdoid tumours of the kidney. Weeks and associates reported on 111 renal rhabdoid cases of which 13.5% also had a central nervous system malignancy. It has been hypothesized that a germline INI mutation may predispose a child to these tumours. There have been some references in the literature alluding to a new diagnosis called rhabdoid predisposition syndrome related to the gene <a href="/wiki/SMARCB1" title="SMARCB1">hSNF5/INI1</a>. </p><p>These tumours have been associated with mutations in the SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (<a href="/wiki/SMARCB1" title="SMARCB1">SMARCB1</a>) located on the long arm of <a href="/wiki/Chromosome_22" title="Chromosome 22">chromosome 22</a> (22q11) and transcription activator BRG1/ATP-dependent chromatin remodeler (<a href="/wiki/SMARCA4" title="SMARCA4">SMARCA4</a>) located on the short arm of <a href="/wiki/Chromosome_19" title="Chromosome 19">chromosome 19</a> (19p13.2).<sup id="cite_ref-Finetti2020_3-0" class="reference"><a href="#cite_note-Finetti2020-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading3"><h3 id="Rhabdoid_tumours_in_kidney_and_brain">Rhabdoid tumours in kidney and brain</h3><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=2" title="Edit section: Rhabdoid tumours in kidney and brain"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Considerable debate has been focused on whether atypical teratoid rhabdoid tumors are the same as rhabdoid tumours of the kidney (i.e., just extrarenal MRTs).<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (October 2021)">citation needed</span></a></i>]</sup> </p><p>Recognition that both CNS atypical teratoid/rhabdoid tumours and MRTs have deletions of the INI1 gene in chromosome 22 indicates that rhabdoid tumours of the kidney and brain are identical or closely related entities, although the CNS variant tends to have its mutations on Taxon <sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Identifying_reliable_sources_(medicine)" title="Wikipedia:Identifying reliable sources (medicine)"><span title="Material near this tag needs references to reliable medical sources. (March 2021)">medical citation needed</span></a></i>]</sup> 9 and MRTs elsewhere. This observation is not surprising because rhabdoid tumours at both locations possess similar histologic, clinical, and demographic features. Moreover, 10-15% of patients with MRTs have synchronous or metachronous brain tumours, many of which are second primary malignant rhabdoid tumours. This similarity excludes composite rhabdoid tumours, which occur mainly in adults.<sup class="noprint Inline-Template Template-Fact" style="white-space:nowrap;">[<i><a href="/wiki/Wikipedia:Citation_needed" title="Wikipedia:Citation needed"><span title="This claim needs references to reliable sources. (October 2021)">citation needed</span></a></i>]</sup> </p> <div class="mw-heading mw-heading2"><h2 id="Diagnosis">Diagnosis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=3" title="Edit section: Diagnosis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <figure class="mw-default-size" typeof="mw:File/Thumb"><a href="/wiki/File:Rhabdoid_tumor.jpg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Rhabdoid_tumor.jpg/220px-Rhabdoid_tumor.jpg" decoding="async" width="220" height="155" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/08/Rhabdoid_tumor.jpg/330px-Rhabdoid_tumor.jpg 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/08/Rhabdoid_tumor.jpg/440px-Rhabdoid_tumor.jpg 2x" data-file-width="725" data-file-height="512" /></a><figcaption>Rhabdoid tumour</figcaption></figure> <p>The histologic diagnosis of malignant rhabdoid tumour depends on identification of characteristic rhabdoid cells—large cells with eccentrically located nuclei and abundant, eosinophilic cytoplasm. However, the histology can be heterogeneous and the diagnosis of MRT can often be difficult. Misclassifications can occur. </p><p>In MRTs, the INI1 gene (SMARCB1) on chromosome 22q functions as a classic <a href="/wiki/Tumour_suppressor_gene" class="mw-redirect" title="Tumour suppressor gene">tumour suppressor gene</a>. Inactivation of INI1 can occur via deletion, mutation, or acquired <a href="/wiki/Uniparental_disomy" title="Uniparental disomy">uniparental disomy</a> (UPD).<sup id="cite_ref-Jackson09_4-0" class="reference"><a href="#cite_note-Jackson09-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p><p>In a recent study,<sup id="cite_ref-Jackson09_4-1" class="reference"><a href="#cite_note-Jackson09-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> Single nucleotide polymorphism array karyotyping identified deletions or <a href="/wiki/Loss_of_heterozygosity" title="Loss of heterozygosity">loss of heterozygosity</a> (LOH) of 22q in 49/51 rhabdoid tumours. Of these, 14 were <a href="/wiki/Copy_neutral_LOH" class="mw-redirect" title="Copy neutral LOH">copy neutral LOH</a> (or acquired UPD), which is detectable by SNP array karyotyping, but not by FISH, cytogenetics, or array CGH. MLPA detected a single exon homozygous deletion in one sample that was below the resolution of the SNP array. <a href="/wiki/Virtual_Karyotype" class="mw-redirect" title="Virtual Karyotype">SNP array karyotyping</a> can be used to distinguish, for example, a <a href="/wiki/Medulloblastoma" title="Medulloblastoma">medulloblastoma</a> with an <a href="/wiki/Isochromosome" title="Isochromosome">isochromosome</a> 17q from a primary rhabdoid tumour with loss of 22q11.2. When indicated, molecular analysis of INI1 using MLPA and direct sequencing may then be employed. Once the tumour-associated changes are found, an analysis of germline DNA from the patient and the parents can be done to rule out an inherited or de novo <a href="/wiki/Germline_mutation" title="Germline mutation">germline mutation</a> or deletion of INI1, so that appropriate recurrence risk assessments can be made.<sup id="cite_ref-Jackson09_4-2" class="reference"><a href="#cite_note-Jackson09-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Prognosis">Prognosis</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=4" title="Edit section: Prognosis"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Regardless of location, all rhabdoid tumours are highly aggressive, have a poor prognosis, and tend to occur in children less than two years of age. </p> <div class="mw-heading mw-heading2"><h2 id="See_also">See also</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=5" title="Edit section: See also"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Epithelioid_sarcoma" title="Epithelioid sarcoma">Epithelioid sarcoma</a></li> <li><a href="/wiki/Atypical_teratoid_rhabdoid_tumor" title="Atypical teratoid rhabdoid tumor">Atypical teratoid rhabdoid tumour</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=6" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap"><ol class="references"> <li id="cite_note-pmid206343-1"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid206343_1-0">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite id="CITEREFBeckwithPalmer1978" class="citation journal cs1">Beckwith JB, Palmer NF (1978). <a rel="nofollow" class="external text" href="https://doi.org/10.1002%2F1097-0142%28197805%2941%3A5%3C1937%3A%3AAID-CNCR2820410538%3E3.0.CO%3B2-U">"Histopathology and prognosis of Wilms tumors: results from the First National Wilms' Tumor Study"</a>. <i>Cancer</i>. <b>41</b> (5): 1937–48. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1002%2F1097-0142%28197805%2941%3A5%3C1937%3A%3AAID-CNCR2820410538%3E3.0.CO%3B2-U">10.1002/1097-0142(197805)41:5<1937::AID-CNCR2820410538>3.0.CO;2-U</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/206343">206343</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Cancer&rft.atitle=Histopathology+and+prognosis+of+Wilms+tumors%3A+results+from+the+First+National+Wilms%27+Tumor+Study&rft.volume=41&rft.issue=5&rft.pages=1937-48&rft.date=1978&rft_id=info%3Adoi%2F10.1002%2F1097-0142%28197805%2941%3A5%3C1937%3A%3AAID-CNCR2820410538%3E3.0.CO%3B2-U&rft_id=info%3Apmid%2F206343&rft.aulast=Beckwith&rft.aufirst=JB&rft.au=Palmer%2C+NF&rft_id=https%3A%2F%2Fdoi.org%2F10.1002%252F1097-0142%2528197805%252941%253A5%253C1937%253A%253AAID-CNCR2820410538%253E3.0.CO%253B2-U&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></span> </li> <li id="cite_note-2"><span class="mw-cite-backlink"><b><a href="#cite_ref-2">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPJ_BiggsGaren_PDPowers_JMGarvin_AJ1987" class="citation journal cs1">PJ Biggs; Garen PD; Powers JM; Garvin AJ (1987). "Malignant rhabdoid tumor of the central nervous system". <i>Human Pathology</i>. <b>18</b> (4): 332–337. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0046-8177%2887%2980161-2">10.1016/S0046-8177(87)80161-2</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/3030922">3030922</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Human+Pathology&rft.atitle=Malignant+rhabdoid+tumor+of+the+central+nervous+system&rft.volume=18&rft.issue=4&rft.pages=332-337&rft.date=1987&rft_id=info%3Adoi%2F10.1016%2FS0046-8177%2887%2980161-2&rft_id=info%3Apmid%2F3030922&rft.au=PJ+Biggs&rft.au=Garen+PD&rft.au=Powers+JM&rft.au=Garvin+AJ&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></span> </li> <li id="cite_note-Finetti2020-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-Finetti2020_3-0">^</a></b></span> <span class="reference-text">Finetti MA, Grabovska Y, Bailey S, Williamson D (2020) Translational genomics of malignant rhabdoid tumours: Current impact and future possibilities. Semin Cancer Biol </span> </li> <li id="cite_note-Jackson09-4"><span class="mw-cite-backlink">^ <a href="#cite_ref-Jackson09_4-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-Jackson09_4-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-Jackson09_4-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJacksonSievertGai2009" class="citation journal cs1">Jackson EM, Sievert AJ, Gai X, et al. (March 2009). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668138">"Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors"</a>. <i>Clin. Cancer Res</i>. <b>15</b> (6): 1923–30. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1158%2F1078-0432.CCR-08-2091">10.1158/1078-0432.CCR-08-2091</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668138">2668138</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/19276269">19276269</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Clin.+Cancer+Res.&rft.atitle=Genomic+analysis+using+high-density+single+nucleotide+polymorphism-based+oligonucleotide+arrays+and+multiplex+ligation-dependent+probe+amplification+provides+a+comprehensive+analysis+of+INI1%2FSMARCB1+in+malignant+rhabdoid+tumors&rft.volume=15&rft.issue=6&rft.pages=1923-30&rft.date=2009-03&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2668138%23id-name%3DPMC&rft_id=info%3Apmid%2F19276269&rft_id=info%3Adoi%2F10.1158%2F1078-0432.CCR-08-2091&rft.aulast=Jackson&rft.aufirst=EM&rft.au=Sievert%2C+AJ&rft.au=Gai%2C+X&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC2668138&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="Literature">Literature</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=7" title="Edit section: Literature"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239549316">.mw-parser-output .refbegin{margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}@media screen{.mw-parser-output .refbegin{font-size:90%}}</style><div class="refbegin" style=""> <ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFDonnerWainwrightZhangBiegel2007" class="citation journal cs1">Donner LR, Wainwright LM, Zhang F, Biegel JA (2007). <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963314">"Mutation of the INI1 gene in composite rhabdoid tumor of the endometrium"</a>. <i>Hum. Pathol</i>. <b>38</b> (6): 935–9. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2Fj.humpath.2006.12.003">10.1016/j.humpath.2006.12.003</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1963314">1963314</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/17376508">17376508</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Hum.+Pathol.&rft.atitle=Mutation+of+the+INI1+gene+in+composite+rhabdoid+tumor+of+the+endometrium&rft.volume=38&rft.issue=6&rft.pages=935-9&rft.date=2007&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1963314%23id-name%3DPMC&rft_id=info%3Apmid%2F17376508&rft_id=info%3Adoi%2F10.1016%2Fj.humpath.2006.12.003&rft.aulast=Donner&rft.aufirst=LR&rft.au=Wainwright%2C+LM&rft.au=Zhang%2C+F&rft.au=Biegel%2C+JA&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1963314&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFJeffrey_S_Dome,_MDD_Ashley_Hill,_MD2007" class="citation journal cs1">Jeffrey S Dome, MD; D Ashley Hill, MD (January 8, 2007). <a rel="nofollow" class="external text" href="http://www.emedicine.com/ped/topic3012.htm#target1">"Malignant Rhabdoid Tumor"</a>. <i>EMedicine from WebMD</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=EMedicine+from+WebMD&rft.atitle=Malignant+Rhabdoid+Tumor&rft.date=2007-01-08&rft.au=Jeffrey+S+Dome%2C+MD&rft.au=D+Ashley+Hill%2C+MD&rft_id=http%3A%2F%2Fwww.emedicine.com%2Fped%2Ftopic3012.htm%23target1&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFPerryFullerJudkinsDehner2005" class="citation journal cs1">Perry A, Fuller CE, Judkins AR, Dehner LP, Biegel JA (2005). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fmodpathol.3800375">"INI1 expression is retained in composite rhabdoid tumors, including rhabdoid meningiomas"</a>. <i>Mod. Pathol</i>. <b>18</b> (7): 951–8. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fmodpathol.3800375">10.1038/modpathol.3800375</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/15761491">15761491</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mod.+Pathol.&rft.atitle=INI1+expression+is+retained+in+composite+rhabdoid+tumors%2C+including+rhabdoid+meningiomas&rft.volume=18&rft.issue=7&rft.pages=951-8&rft.date=2005&rft_id=info%3Adoi%2F10.1038%2Fmodpathol.3800375&rft_id=info%3Apmid%2F15761491&rft.aulast=Perry&rft.aufirst=A&rft.au=Fuller%2C+CE&rft.au=Judkins%2C+AR&rft.au=Dehner%2C+LP&rft.au=Biegel%2C+JA&rft_id=https%3A%2F%2Fdoi.org%2F10.1038%252Fmodpathol.3800375&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBiegelFogelgrenWainwrightZhou2000" class="citation journal cs1">Biegel JA, Fogelgren B, Wainwright LM, Zhou JY, Bevan H, Rorke LB (2000). <a rel="nofollow" class="external text" href="http://cancerres.aacrjournals.org/cgi/content/abstract/59/1/74">"Germline INI1 mutation in a patient with a central nervous system atypical teratoid tumor and renal rhabdoid tumor"</a> <span class="cs1-format">(abstract page)</span>. <i>Genes Chromosomes Cancer</i>. <b>28</b> (1): 31–7. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="id-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1002%2F%28SICI%291098-2264%28200005%2928%3A1%3C31%3A%3AAID-GCC4%3E3.0.CO%3B2-Y">10.1002/(SICI)1098-2264(200005)28:1<31::AID-GCC4>3.0.CO;2-Y</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/10738300">10738300</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:21250260">21250260</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genes+Chromosomes+Cancer&rft.atitle=Germline+INI1+mutation+in+a+patient+with+a+central+nervous+system+atypical+teratoid+tumor+and+renal+rhabdoid+tumor&rft.volume=28&rft.issue=1&rft.pages=31-7&rft.date=2000&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A21250260%23id-name%3DS2CID&rft_id=info%3Apmid%2F10738300&rft_id=info%3Adoi%2F10.1002%2F%28SICI%291098-2264%28200005%2928%3A1%3C31%3A%3AAID-GCC4%3E3.0.CO%3B2-Y&rft.aulast=Biegel&rft.aufirst=JA&rft.au=Fogelgren%2C+B&rft.au=Wainwright%2C+LM&rft.au=Zhou%2C+JY&rft.au=Bevan%2C+H&rft.au=Rorke%2C+LB&rft_id=http%3A%2F%2Fcancerres.aacrjournals.org%2Fcgi%2Fcontent%2Fabstract%2F59%2F1%2F74&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFHuretSevenet2000" class="citation journal cs1">Huret J, Sevenet N (2000). <a rel="nofollow" class="external text" href="https://web.archive.org/web/20051226201640/http://www.infobiogen.fr/services/chromcancer/Kprones/rhabdKpronID10051.html">"Rhabdoid predispoition syndrome"</a>. <i>Atlas of Genetics and Cytogenetics in Oncology and Haematology</i> (1): 31–7. Archived from <a rel="nofollow" class="external text" href="http://www.infobiogen.fr/services/chromcancer/Kprones/rhabdKpronID10051.html">the original</a> on 2005-12-26.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Atlas+of+Genetics+and+Cytogenetics+in+Oncology+and+Haematology&rft.atitle=Rhabdoid+predispoition+syndrome&rft.issue=1&rft.pages=31-7&rft.date=2000&rft.aulast=Huret&rft.aufirst=J&rft.au=Sevenet%2C+N&rft_id=http%3A%2F%2Fwww.infobiogen.fr%2Fservices%2Fchromcancer%2FKprones%2FrhabdKpronID10051.html&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></li> <li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFWeeksBeckwithMierauLuckey1989" class="citation journal cs1">Weeks DA, Beckwith JB, Mierau GW, Luckey DW (1989). "Rhabdoid tumor of kidney. A report of 111 cases from the National Wilms' Tumor Study Pathology Center". <i>American Journal of Surgical Pathology</i>. <b>13</b> (6): 439–58. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1097%2F00000478-198906000-00001">10.1097/00000478-198906000-00001</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="https://pubmed.ncbi.nlm.nih.gov/2543225">2543225</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:19589843">19589843</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=American+Journal+of+Surgical+Pathology&rft.atitle=Rhabdoid+tumor+of+kidney.+A+report+of+111+cases+from+the+National+Wilms%27+Tumor+Study+Pathology+Center&rft.volume=13&rft.issue=6&rft.pages=439-58&rft.date=1989&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A19589843%23id-name%3DS2CID&rft_id=info%3Apmid%2F2543225&rft_id=info%3Adoi%2F10.1097%2F00000478-198906000-00001&rft.aulast=Weeks&rft.aufirst=DA&rft.au=Beckwith%2C+JB&rft.au=Mierau%2C+GW&rft.au=Luckey%2C+DW&rfr_id=info%3Asid%2Fen.wikipedia.org%3AMalignant+rhabdoid+tumour" class="Z3988"></span></li></ul> </div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Malignant_rhabdoid_tumour&action=edit&section=8" title="Edit section: External links"><span>edit</span></a><span 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class="navbox-group" style="width:1%;background: #EAECF0;color:black;">Classification</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"><div style="position:relative; float:right; font-size:0.8em;"><a href="https://www.wikidata.org/wiki/Q6743515" class="extiw" title="d:Q6743515">D</a></div><div class="hlist" style="text-align:left;"><ul><li><b><a href="/wiki/International_Classification_of_Diseases_for_Oncology" title="International Classification of Diseases for Oncology">ICD-O</a></b>: 8963/3</li><li><b><a href="/wiki/Online_Mendelian_Inheritance_in_Man" title="Online Mendelian Inheritance in Man">OMIM</a></b>: <a rel="nofollow" class="external text" href="https://omim.org/entry/609322">609322</a></li><li><b><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a></b>: <a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D018335">D018335</a></li></ul></div></div></td></tr></tbody></table></div> <div class="navbox-styles"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1236075235"></div><div role="navigation" class="navbox" aria-labelledby="Connective/soft_tissue_tumors_and_sarcomas" style="padding:3px"><table class="nowraplinks mw-collapsible autocollapse navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="col" class="navbox-title" colspan="2"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1129693374"><style data-mw-deduplicate="TemplateStyles:r1239400231">.mw-parser-output .navbar{display:inline;font-size:88%;font-weight:normal}.mw-parser-output .navbar-collapse{float:left;text-align:left}.mw-parser-output .navbar-boxtext{word-spacing:0}.mw-parser-output .navbar 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digital fibromatosis">Infantile digital fibromatosis</a></li> <li><a href="/wiki/Juvenile_hyaline_fibromatosis" title="Juvenile hyaline fibromatosis">Juvenile hyaline fibromatosis</a></li> <li><a href="/wiki/Plantar_fibromatosis" title="Plantar fibromatosis">Plantar fibromatosis</a></li> <li><a href="/wiki/Pleomorphic_fibroma" title="Pleomorphic fibroma">Pleomorphic fibroma</a></li> <li><a href="/wiki/Oral_submucous_fibrosis" title="Oral submucous fibrosis">Oral submucous fibrosis</a></li> <li><a href="/wiki/Pachydermodactyly" title="Pachydermodactyly">Pachydermodactyly</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Histiocytoma" title="Histiocytoma">Histiocytoma</a>/<a href="/wiki/Histiocytic_sarcoma" title="Histiocytic sarcoma">histiocytic sarcoma</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Benign_fibrous_histiocytoma" class="mw-redirect" title="Benign fibrous histiocytoma">Benign fibrous histiocytoma</a></li> <li><a href="/wiki/Pleomorphic_undifferentiated_sarcoma" class="mw-redirect" title="Pleomorphic undifferentiated sarcoma">Malignant fibrous histiocytoma</a></li> <li><a href="/wiki/Atypical_fibroxanthoma" title="Atypical fibroxanthoma">Atypical fibroxanthoma</a></li> <li><a href="/wiki/Solitary_fibrous_tumor" title="Solitary fibrous tumor">Solitary fibrous tumor</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Myxoma" title="Myxoma">Myxomatous</a></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Myxoma" title="Myxoma">Myxoma</a>/<a href="/wiki/Myxosarcoma" title="Myxosarcoma">myxosarcoma</a> <ul><li><a href="/wiki/Cutaneous_myxoma" title="Cutaneous myxoma">Cutaneous myxoma</a></li> <li><a href="/wiki/Superficial_acral_fibromyxoma" title="Superficial acral fibromyxoma">Superficial acral fibromyxoma</a></li></ul></li> <li><a href="/wiki/Aggressive_angiomyxoma" title="Aggressive angiomyxoma">Angiomyxoma</a></li> <li><a href="/wiki/Ossifying_fibromyxoid_tumour" title="Ossifying fibromyxoid tumour">Ossifying fibromyxoid tumour</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Fibroepithelial_neoplasms" class="mw-redirect" title="Fibroepithelial neoplasms">Fibroepithelial</a></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Brenner_tumour" title="Brenner tumour">Brenner tumour</a></li> <li><a href="/wiki/Fibroadenoma" title="Fibroadenoma">Fibroadenoma</a></li> <li><a href="/wiki/Phyllodes_tumor" title="Phyllodes tumor">Phyllodes tumor</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Synovial_joint" title="Synovial joint">Synovial</a>-like</th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Synovial_sarcoma" title="Synovial sarcoma">Synovial sarcoma</a></li> <li><a href="/wiki/Clear-cell_sarcoma" class="mw-redirect" title="Clear-cell sarcoma">Clear-cell sarcoma</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Adipose_tissue_neoplasm" title="Adipose tissue neoplasm">Lipomatous</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Lipoma" title="Lipoma">Lipoma</a>/<a href="/wiki/Liposarcoma" title="Liposarcoma">liposarcoma</a> <ul><li><a href="/wiki/Myelolipoma" title="Myelolipoma">Myelolipoma</a></li> <li><a href="/wiki/Myxoid_liposarcoma" title="Myxoid liposarcoma">Myxoid liposarcoma</a></li></ul></li> <li><a href="/wiki/Perivascular_epithelioid_cell_tumour" title="Perivascular epithelioid cell tumour">PEComa</a> <ul><li><a href="/wiki/Angiomyolipoma" title="Angiomyolipoma">Angiomyolipoma</a></li></ul></li></ul> <ul><li><a href="/wiki/Chondroid_lipoma" title="Chondroid lipoma">Chondroid lipoma</a></li> <li><a href="/wiki/Intradermal_spindle_cell_lipoma" class="mw-redirect" title="Intradermal spindle cell lipoma">Intradermal spindle cell lipoma</a></li> <li><a href="/wiki/Pleomorphic_lipoma" title="Pleomorphic lipoma">Pleomorphic lipoma</a></li> <li><a href="/wiki/Lipoblastomatosis" title="Lipoblastomatosis">Lipoblastomatosis</a></li> <li><a href="/wiki/Spindle_cell_lipoma" title="Spindle cell lipoma">Spindle cell lipoma</a></li> <li><a href="/wiki/Hibernoma" title="Hibernoma">Hibernoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Muscle_tissue_neoplasm" class="mw-redirect" title="Muscle tissue neoplasm">Myomatous</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"></div><table class="nowraplinks navbox-subgroup" style="border-spacing:0"><tbody><tr><th scope="row" class="navbox-group" style="width:1%"><span class="nobold">General</span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Myoma" title="Myoma">Myoma</a>/<a href="/wiki/Myosarcoma" title="Myosarcoma">myosarcoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="nobold"><a href="/wiki/Smooth_muscle_tissue" class="mw-redirect" title="Smooth muscle tissue">Smooth muscle</a></span></th><td class="navbox-list-with-group navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Leiomyoma" title="Leiomyoma">Leiomyoma</a>/<a href="/wiki/Leiomyosarcoma" title="Leiomyosarcoma">leiomyosarcoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><span class="nobold"><a href="/wiki/Skeletal_muscle" title="Skeletal muscle">Skeletal muscle</a></span></th><td class="navbox-list-with-group navbox-list navbox-odd" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Rhabdomyoma" title="Rhabdomyoma">Rhabdomyoma</a>/<a href="/wiki/Rhabdomyosarcoma" title="Rhabdomyosarcoma">rhabdomyosarcoma</a>: <a href="/wiki/Embryonal_rhabdomyosarcoma" title="Embryonal rhabdomyosarcoma">Embryonal rhabdomyosarcoma</a> <ul><li><a href="/wiki/Sarcoma_botryoides" title="Sarcoma botryoides">Sarcoma botryoides</a></li></ul></li> <li><a href="/wiki/Alveolar_rhabdomyosarcoma" title="Alveolar rhabdomyosarcoma">Alveolar rhabdomyosarcoma</a></li></ul> </div></td></tr><tr><td colspan="2" class="navbox-list navbox-even" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Leiomyoma" title="Leiomyoma">Leiomyoma</a> <ul><li><a href="/wiki/Cutaneous_leiomyoma" title="Cutaneous leiomyoma">Cutaneous</a></li></ul></li> <li><a href="/wiki/Angioleiomyoma" title="Angioleiomyoma">Angioleiomyoma</a></li> <li><a href="/wiki/Angiolipoleiomyoma" title="Angiolipoleiomyoma">Angiolipoleiomyoma</a></li> <li><a href="/wiki/Genital_leiomyoma" title="Genital leiomyoma">Genital leiomyoma</a></li> <li><a href="/wiki/Leiomyosarcoma" title="Leiomyosarcoma">Leiomyosarcoma</a></li> <li><a href="/wiki/Hereditary_leiomyomatosis_and_renal_cell_cancer_syndrome" title="Hereditary leiomyomatosis and renal cell cancer syndrome">Multiple cutaneous and uterine leiomyomatosis syndrome</a></li> <li><a href="/wiki/Multiple_cutaneous_leiomyoma" class="mw-redirect" title="Multiple cutaneous leiomyoma">Multiple cutaneous leiomyoma</a></li> <li><a href="/wiki/Neural_fibrolipoma" title="Neural fibrolipoma">Neural fibrolipoma</a></li> <li><a href="/wiki/Solitary_cutaneous_leiomyoma" class="mw-redirect" title="Solitary cutaneous leiomyoma">Solitary cutaneous leiomyoma</a></li> <li><a href="/wiki/Smooth_muscle_tumor_of_uncertain_malignant_potential" title="Smooth muscle tumor of uncertain malignant potential">STUMP</a></li></ul> </div></td></tr></tbody></table><div></div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Complex_and_mixed_tumor" class="mw-redirect" title="Complex and mixed tumor">Complex mixed and stromal</a></th><td class="navbox-list-with-group navbox-list navbox-odd hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Adenomyoma" title="Adenomyoma">Adenomyoma</a></li> <li><a href="/wiki/Pleomorphic_adenoma" title="Pleomorphic adenoma">Pleomorphic adenoma</a></li> <li><a href="/wiki/Mixed_M%C3%BCllerian_tumor" title="Mixed Müllerian tumor">Mixed Müllerian tumor</a></li> <li><a href="/wiki/Mesoblastic_nephroma" title="Mesoblastic nephroma">Mesoblastic nephroma</a></li> <li><a href="/wiki/Wilms%27_tumor" title="Wilms' tumor">Wilms' tumor</a></li> <li><a class="mw-selflink selflink">Malignant rhabdoid tumour</a></li> <li><a href="/wiki/Clear-cell_sarcoma_of_the_kidney" title="Clear-cell sarcoma of the kidney">Clear-cell sarcoma of the kidney</a></li> <li><a href="/wiki/Hepatoblastoma" title="Hepatoblastoma">Hepatoblastoma</a></li> <li><a href="/wiki/Pancreatoblastoma" title="Pancreatoblastoma">Pancreatoblastoma</a></li> <li><a href="/wiki/Carcinosarcoma" title="Carcinosarcoma">Carcinosarcoma</a></li></ul> </div></td></tr><tr><th scope="row" class="navbox-group" style="width:1%"><a href="/wiki/Mesothelium" title="Mesothelium">Mesothelial</a></th><td class="navbox-list-with-group navbox-list navbox-even hlist" style="width:100%;padding:0"><div style="padding:0 0.25em"> <ul><li><a href="/wiki/Mesothelioma" title="Mesothelioma">Mesothelioma</a></li> <li><a href="/wiki/Adenomatoid_tumor" title="Adenomatoid tumor">Adenomatoid tumor</a></li></ul> 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