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class="sr-only">Home</span></a> <a href="/" class="homeactiveitem mainmenu js-nav-system__link">Home</a> <div class="grantees js-nav-system__item"> <a href="/eracommons-timeline.htm" class="mainmenu js-nav-system__link " style="text-transform:none">NEW TO eRA COMMONS</a></div> <div class="applicants js-nav-system__item"> <a href="/applicants" class="mainmenu js-nav-system__link activeitem">Applicants</a> <div class="applicants-menu hide js-nav-system__subnav"> <div class="sub-section-how-to-apply"> <h4>To Apply</h4> <div class="sub-section-item js-nav-system__subnav__item"><a href="https://grants.nih.gov/grants/How-to-Apply-Application-Guide.htm" class="js-nav-system__subnav__link">How to Apply — Application Guide</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="https://grants.nih.gov/grants/how-to-apply-application-guide/prepare-to-apply-and-register/submission-options/assist.htm" class="js-nav-system__subnav__link">Preparing Your Application Using 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class="sub-section-item js-nav-system__subnav__item"><a href="/recipients/seek-prior-approval-for-withdrawal-of-grant" class="js-nav-system__subnav__link">Seek Prior Approval (If Needed)</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/recipients/manage-trainees-fellows.htm" class="js-nav-system__subnav__link">Manage Trainees, and Fellows</a></div> </div> <div class="sub-section-submit-closeout"> <h4>Closeout</h4> <div class="sub-section-item js-nav-system__subnav__item"><a href="/recipients/submit-closeout.htm" class="js-nav-system__subnav__link">Submit Closeout</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/recipients/financial-status-report.htm" class="js-nav-system__subnav__link">Submit Federal Financial Report (FFR)</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/recipients/submit-final-rppr.htm" class="js-nav-system__subnav__link">Submit Final RPPR</a></div> <div class="sub-section-item 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js-nav-system__subnav__item"><a href="/reviewers/certify-confidentiality-statement.htm" class="js-nav-system__subnav__link">Certify Confidentiality Statement</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/certify-employment.htm" class="js-nav-system__subnav__link">Certify Employment</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/check-conflicts.htm" class="js-nav-system__subnav__link">Check Conflicts (Recruitment Phase)</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewer/pre-meeting-coi.htm" class="js-nav-system__subnav__link">Certify Pre-Meeting COI</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/take-required-training.htm" class="js-nav-system__subnav__link">Take Required Review Integrity & Bias Awareness Training</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/access-meeting-materials.htm" class="js-nav-system__subnav__link">Access Meeting Materials</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/access-applications.htm" class="js-nav-system__subnav__link">Access Applications</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/access-critique-templates.htm" class="js-nav-system__subnav__link">Access Critique Template(s)</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/critique-scores.htm" class="js-nav-system__subnav__link">Submit & Manage Critiques, Scores</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/view-all-critiques.htm" class="js-nav-system__subnav__link">View Other Reviewers Critiques</a></div> </div> <div class="sub-section-atmeeting" style="margin-bottom: 60px;" > <h4>At Meeting</h4> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/submit-final-scores.htm" class="js-nav-system__subnav__link">Submit Final Scores</a></div> </div> <div class="sub-section-postmeeting" style="clear: right;"> <h4>Post-Meeting</h4> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/post-meeting-coi.htm" class="js-nav-system__subnav__link">Certify Post-Meeting COI</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/reviewers/edit-critiques.htm" class="js-nav-system__subnav__link">Edit Critiques</a></div> </div> </div> </div> <div class="manage-accounts js-nav-system__item"> <a href="/register-accounts" class="mainmenu js-nav-system__link ">Accounts</a> <div class="manage-accounts-menu hide js-nav-system__subnav"> <div class="sub-section-how-to"> <h4>How to</h4> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/understanding-era-commons-accounts.htm" class="js-nav-system__subnav__link">Understanding eRA Commons Accounts</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/register-in-era-commons.htm" class="js-nav-system__subnav__link">Register Your Institution in eRA Commons</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/manage-institutional-profile.htm" class="js-nav-system__subnav__link">Manage Institutional Profile</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/access-era-modules-via-login-gov.htm" class="js-nav-system__subnav__link">Two-Factor Authentication: <br> Access eRA Modules via Login.gov</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/access-modules-with-federated-account.htm" class="js-nav-system__subnav__link">Two-Factor Authentication: <br> Access eRA Modules via an InCommon Federated Account</a></div> </div> <div class="sub-section-manage-accounts"> <h4>Manage Accounts</h4> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/create-and-edit-an-account.htm" class="js-nav-system__subnav__link">Create and Edit an Account</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/account-roles.htm" class="js-nav-system__subnav__link">Account Roles</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/manage-delegation.htm" class="js-nav-system__subnav__link">Manage Delegation</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/manage-personal-profile.htm" class="js-nav-system__subnav__link">Manage Personal Profile</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/change-password.htm" class="js-nav-system__subnav__link">Change Password</a></div> <div class="sub-section-item js-nav-system__subnav__item"><a href="/register-accounts/affiliation.htm" class="js-nav-system__subnav__link">Manage Affiliation</a></div> </div> </div> </div> <a href="/news" class="mainmenu js-nav-system__link ">News</a> <a href="/about-era" class="mainmenu js-nav-system__link ">About <span style="text-transform: lowercase;">e</span>RA | AGENCY PARTNERSHIP</a> </div> <a href="/faqs.htm" class="mainmenu js-nav-system__link mobile-only">FAQs</a> <a href="/about-era/get-connected.htm" class="mainmenu js-nav-system__link mobile-only">Subscribe</a> <a href="https://grants.nih.gov/grants/glossary.htm" class="mainmenu js-nav-system__link mobile-only">Glossary</a> <a href="https://inside.era.nih.gov/" class="mainmenu js-nav-system__link mobile-only">eRA Intranet</a> <a href="https://www.era.nih.gov/need-help" class="mainmenu js-nav-system__link mobile-only">Need Help?</a> </div> <div style="height:4px; background-color:#41505f"></div>  <div class="graybackground-breadcrumbs"></div> <div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> <div role="main" class="main-container container js-quickedit-main-content"> <div class="row"> <div class="col-sm-12" role="heading"> <div class="region region-header"> <ol class="breadcrumb"> <li > <a href="/">Home</a> </li> <li > <a href="https://www.era.nih.gov/applicants">Applicants</a> </li> <li > System-to-System (S2S) </li> </ol> <div data-drupal-messages-fallback class="hidden"></div> </div> </div> <aside class="col-sm-3 first-sidebar" role="complementary"> <div class="region region-sidebar-first"> <section id="block-applicantsleftnav" class="block block-block-content block-block-content5c167766-b412-49ad-89ea-b76e4e7a6e44 clearfix"> <h2 class="block-title">Applicants</h2> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><div class="main-section-how-to-apply"> <h4>To Apply</h4> <div class="arrows"><span class="arrow-up is-hidden">▲</span> <span class="arrow-down">▼</span></div> <div class="section-item"><a href="https://grants.nih.gov/grants/How-to-Apply-Application-Guide.htm">How to Apply — Application Guide</a> <div class="active-arrow hide"> </div> </div> <div class="section-item"><a href="https://grants.nih.gov/grants/how-to-apply-application-guide/prepare-to-apply-and-register/submission-options/assist.htm">Preparing Your Application Using ASSIST</a> <div class="active-arrow-large hide"> </div> </div> <div class="section-item"><a href="/applicants/system">Information for System-to-System Developers</a> <div class="active-arrow-large hide"> </div> </div> <div class="section-item"><a href="/applicants/sek-prior-approval-applicants.htm">Seek Prior Approval for Withdrawal of Application</a> <div class="active-arrow-large hide"> </div> </div> <div class="section-item"><a href="/applicants/reference-letter.htm">Have a Referee Submit A Reference Letter (If Needed)</a> <div class="active-arrow-large hide"> </div> </div> </div> <div class="main-section-after-submission"> <h4>After Submission</h4> <div class="arrows"><span class="arrow-up is-hidden">▲</span> <span class="arrow-down">▼</span></div> <div class="section-item"><a href="https://grants.nih.gov/grants/how-to-apply-application-guide/submission-process/submit-track-view.htm">Submit,Track,and View Application</a> <div class="active-arrow-large hide"> </div> </div> <div class="section-item"><a href="/applicants/view-ss-scores.htm">View Review Outcome</a> <div class="active-arrow hide"> </div> </div> <div class="section-item"><a href="/applicants/submit-jit.htm">Submit Just-in-Time (If Needed)</a> <div class="active-arrow hide"> </div> </div> <div class="section-item"><a href="/grantees/view-notice-of-award.htm">View Notice of Award</a> <div class="active-arrow hide"> </div> </div> </div> </div> </section> </div> </aside> <section class="col-sm-6"> <div id="main-content"></div> <div class="region region-content"> <h1 class="page-header"> <span>System-to-System (S2S)</span> </h1> <article data-history-node-id="341" class="page full clearfix"> <div class="content"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><style type="text/css">.grid-wrapper { display:-ms-grid; display:grid; grid-template-columns: repeat(auto-fit, minmax(250px, 1fr)); -ms-grid-columns: 30% 30% 30%; align:center; max-width: 900px; grid-gap:20px; row-gap:30px; -ms-grid-gap: 20px; -ms-row-gap: 30px; -ms-grid-rows: 200px 200px; grid-template-rows: 1fr 1fr; } figure { justify-self: center; align-self:center; text-align:center; } figcaption { font-size: 20px; text-align:center; } </style><div class="grid-wrapper"><figure class="figure" style="-ms-grid-column:1;-ms-grid-row:1;"><a href="/applicants/system/system-testing.htm"><img class="nobaguettebox" src="/themes/era2019/images/s2sicons/testing1.png" alt="Icon of two application windows" width="171" height="147" align="”left”" loading="lazy"></a><figcaption><a href="/applicants/system/system-testing.htm">Testing</a></figcaption></figure><figure class="figure" style="-ms-grid-column:2;-ms-grid-row:1;"><a href="/applicants/validations.htm"><img class="nobaguettebox" src="/themes/era2019/images/s2sicons/validations1.png" alt="Icon of clipboard with a checklist" width="111" height="142" align="”left”" loading="lazy"></a><figcaption><a href="/applicants/system/validations.htm">eRA System-Enforced</a><br><a href="/applicants/system/validations.htm">Validations</a></figcaption></figure><figure class="figure" style="-ms-grid-column:3;-ms-grid-row:1;"><a href="/applicants/system/assembled-applic-images.htm"><img class="nobaguettebox" src="/themes/era2019/images/s2sicons/img1.png" alt="Icon of folder with graphic image" width="140" height="132" align="”left”" loading="lazy"></a><figcaption><a href="/applicants/system/assembled-applic-images.htm">Assembled</a><br><a href="/applicants/system/assembled-applic-images.htm">Application Images</a></figcaption></figure><figure class="figure" style="-ms-grid-column:1;-ms-grid-row:2;"><a href="/applicants/system/system-webserv.htm"><img class="nobaguettebox" src="/themes/era2019/images/s2sicons/webservices1.png" alt="Webpage window icon" width="133" height="116" align="”left”" loading="lazy"></a><figcaption><a href="/applicants/system/system-webserv.htm">eRA Web</a><br><a href="/applicants/system/system-webserv.htm">Services</a></figcaption></figure><figure class="figure" style="-ms-grid-column:2;-ms-grid-row:2;"><a href="/applicants/system/enhancement-validation.htm"><img class="nobaguettebox" src="/themes/era2019/images/s2sicons/enhancement1.png" alt="Computer with refresh icon" width="154" height="131" align="”left”" loading="lazy"></a><figcaption><a href="/applicants/system/enhancement-validation.htm">Enhancement</a><br><a href="/applicants/system/enhancement-validation.htm">and Validations</a></figcaption></figure><figure class="figure" style="-ms-grid-column:3;-ms-grid-row:2;"><a href="/applicants/system/system-issues.htm"><img class="nobaguettebox" src="/themes/era2019/images/s2sicons/issues1.png" alt="Warning icon with turning cogswheel gears" width="156" height="154" align="”left”" loading="lazy"></a><figcaption><a href="/applicants/system/system-issues.htm">Known Issues Affecting</a><br><a href="/applicants/system/system-issues.htm">S2S Applications</a></figcaption></figure></div><h2>Additional Resources</h2><ul><li style="background-color:white;box-sizing:border-box;color:#333333;"><a href="https://www.era.nih.gov/files/how-to-apply-application-guide/Application_Forms_Activity_Code_Mapping_FORMS-H.xls">NIH Application Forms and Activity Code Mapping – FORMS-H</a> (Excel)</li><li class="MsoNormal"><a href="https://www.era.nih.gov/files/how-to-apply-application-guide/Application_Forms_Activity_Code_Mapping_FORMS-I.xls"><span>NIH Application Forms and Activity Code Mapping – FORMS-I</span></a><span> (Excel)</span></li><li><a href="https://grants.nih.gov/grants/funding/424/index.htm#inst">NIH's SF424 (R&R) Application Guides</a></li></ul><h2>NIH System-to-System Listserv</h2><p><a href="/about-era/get-connected.htm">Subscribe</a> for news and updates specific to system-to-system services and test environment information.</p></div> </div> </article> </div>  <div id="embed-survey" style="clear:left; margin-top:20px"></div>  <style> #close{ display:inline; position: fixed; top: 5%; left: 90%; float:right; width:30px; height:29px; background:url(/images/close_icon-l.png) no-repeat center center; z-index:-1 } </style> <script> //This adds the lightbox feature to every image in the body area aka .main-container // $('.main-container img').each(function() { // For each image // if (!$(this).is(".nobaguettebox")) { // var $img = $(this), // href = $img.attr('src'); // $img.wrap('<a class="baguetteBox gallery" href="' + href + '"></a>'); // } // }); </script> </section> <aside class="col-sm-3 second-sidebar" role="complementary"> <div class="well region region-sidebar-second"> <section id="block-informationfors2srightnav" class="block block-block-content block-block-content2f819bfd-4cbc-4da5-8fec-e2dfcb217dc8 clearfix"> <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><div class="applicants-sidebar"><div class="applicants-sidebar-h2">Related Links</div><div class="section-item"><a href="https://grants.nih.gov/funding/nih-guide-for-grants-and-contracts">NIH Guide for Grants and Contracts</a></div><div class="section-item"><a href="https://www.grants.gov/search-grants">Grants.gov Find Grant Opportunities</a></div><div class="section-item"><a href="https://grants.nih.gov/funding/nih-guide-for-grants-and-contracts/parent-announcements">Find Parent Announcements</a></div><div class="section-item"><a href="https://www.era.nih.gov/applicants/system/s2s-technical.htm">S2S Technical Support</a></div></div></div> </section> </div> </aside> </div> </div> <div class ="page-updated"> This page last updated on October 28, 2024<br> Technical Issues: <a href="mailto:OERWebmaster03@od.nih.gov">E-mail OER Webmaster</a> </div> </div> <script> $(document).ready(function(){ $('img').each(function() { if ($(this).width() > 799) { $(this).attr('title', 'To enlarge image, right-click it and open in a new tab'); } }); var url = window.location.href; var wb_url = url; document.getElementById("waybackurl").href="https://web.archive.org/web/*/" + wb_url; //This toggles the leftnav for the Reviewers section $(".main-section-premeeting h4, .main-section-premeeting .arrows").click(function(){ $(".main-section-premeeting .section-item").slideToggle("slow"); $(".main-section-premeeting .arrows").find(".arrow-up, .arrow-down").toggle(); }); $(".main-section-atmeeting h4, .main-section-atmeeting .arrows").click(function(){ $(".main-section-atmeeting .section-item").slideToggle("slow"); $(".main-section-atmeeting .arrows").find(".arrow-up, .arrow-down").toggle(); }); $(".main-section-postmeeting h4, .main-section-postmeeting 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