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Labetalol - Wikipedia, la enciclopedia libre
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href="#Indicación"> <div class="vector-toc-text"> <span class="vector-toc-numb">2</span> <span>Indicación</span> </div> </a> <ul id="toc-Indicación-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Administración" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Administración"> <div class="vector-toc-text"> <span class="vector-toc-numb">3</span> <span>Administración</span> </div> </a> <ul id="toc-Administración-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Efectos_adversos" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Efectos_adversos"> <div class="vector-toc-text"> <span class="vector-toc-numb">4</span> <span>Efectos adversos</span> </div> </a> <ul id="toc-Efectos_adversos-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Contraindicaciones" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Contraindicaciones"> <div class="vector-toc-text"> <span class="vector-toc-numb">5</span> <span>Contraindicaciones</span> </div> </a> <ul id="toc-Contraindicaciones-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Estereoquímica" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Estereoquímica"> <div class="vector-toc-text"> <span class="vector-toc-numb">6</span> <span>Estereoquímica</span> </div> </a> <ul id="toc-Estereoquímica-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Véase_también" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Véase_también"> <div class="vector-toc-text"> <span class="vector-toc-numb">7</span> <span>Véase también</span> </div> </a> <ul id="toc-Véase_también-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Referencias" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Referencias"> <div class="vector-toc-text"> <span class="vector-toc-numb">8</span> <span>Referencias</span> </div> </a> <ul id="toc-Referencias-sublist" class="vector-toc-list"> </ul> </li> <li id="toc-Enlaces_externos" class="vector-toc-list-item vector-toc-level-1 vector-toc-list-item-expanded"> <a class="vector-toc-link" href="#Enlaces_externos"> <div class="vector-toc-text"> <span class="vector-toc-numb">9</span> <span>Enlaces externos</span> </div> </a> <ul id="toc-Enlaces_externos-sublist" class="vector-toc-list"> </ul> </li> </ul> </div> </div> </nav> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <nav aria-label="Contenidos" class="vector-toc-landmark"> <div id="vector-page-titlebar-toc" class="vector-dropdown vector-page-titlebar-toc vector-button-flush-left" > <input type="checkbox" id="vector-page-titlebar-toc-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-titlebar-toc" class="vector-dropdown-checkbox " aria-label="Cambiar a la tabla de contenidos" > <label id="vector-page-titlebar-toc-label" for="vector-page-titlebar-toc-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--icon-only " aria-hidden="true" ><span class="vector-icon mw-ui-icon-listBullet mw-ui-icon-wikimedia-listBullet"></span> <span class="vector-dropdown-label-text">Cambiar a la tabla de contenidos</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-titlebar-toc-unpinned-container" class="vector-unpinned-container"> </div> </div> </div> </nav> <h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Labetalol</span></h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Ir a un artículo en otro idioma. Disponible en 24 idiomas" > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-24" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">24 idiomas</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="interlanguage-link interwiki-ar mw-list-item"><a href="https://ar.wikipedia.org/wiki/%D9%84%D8%A7%D8%A8%D9%8A%D8%AA%D8%A7%D9%84%D9%88%D9%84" title="لابيتالول (árabe)" lang="ar" hreflang="ar" data-title="لابيتالول" data-language-autonym="العربية" data-language-local-name="árabe" class="interlanguage-link-target"><span>العربية</span></a></li><li class="interlanguage-link interwiki-cy mw-list-item"><a href="https://cy.wikipedia.org/wiki/Labetalol" title="Labetalol (galés)" lang="cy" hreflang="cy" data-title="Labetalol" data-language-autonym="Cymraeg" data-language-local-name="galés" class="interlanguage-link-target"><span>Cymraeg</span></a></li><li class="interlanguage-link interwiki-de mw-list-item"><a href="https://de.wikipedia.org/wiki/Labetalol" title="Labetalol (alemán)" lang="de" hreflang="de" data-title="Labetalol" data-language-autonym="Deutsch" data-language-local-name="alemán" class="interlanguage-link-target"><span>Deutsch</span></a></li><li class="interlanguage-link interwiki-el mw-list-item"><a href="https://el.wikipedia.org/wiki/%CE%9B%CE%B1%CE%B2%CE%B5%CF%84%CE%B1%CE%BB%CF%8C%CE%BB%CE%B7" title="Λαβεταλόλη (griego)" lang="el" hreflang="el" data-title="Λαβεταλόλη" data-language-autonym="Ελληνικά" data-language-local-name="griego" class="interlanguage-link-target"><span>Ελληνικά</span></a></li><li class="interlanguage-link interwiki-en mw-list-item"><a href="https://en.wikipedia.org/wiki/Labetalol" title="Labetalol (inglés)" lang="en" hreflang="en" data-title="Labetalol" data-language-autonym="English" data-language-local-name="inglés" class="interlanguage-link-target"><span>English</span></a></li><li class="interlanguage-link interwiki-fa mw-list-item"><a href="https://fa.wikipedia.org/wiki/%D9%84%D8%A7%D8%A8%D8%AA%D8%A7%D9%84%D9%88%D9%84" title="لابتالول (persa)" lang="fa" hreflang="fa" data-title="لابتالول" data-language-autonym="فارسی" data-language-local-name="persa" class="interlanguage-link-target"><span>فارسی</span></a></li><li class="interlanguage-link interwiki-fi mw-list-item"><a href="https://fi.wikipedia.org/wiki/Labetaloli" title="Labetaloli (finés)" lang="fi" hreflang="fi" data-title="Labetaloli" data-language-autonym="Suomi" data-language-local-name="finés" class="interlanguage-link-target"><span>Suomi</span></a></li><li class="interlanguage-link interwiki-fr mw-list-item"><a href="https://fr.wikipedia.org/wiki/Lab%C3%A9talol" title="Labétalol (francés)" lang="fr" hreflang="fr" data-title="Labétalol" data-language-autonym="Français" data-language-local-name="francés" class="interlanguage-link-target"><span>Français</span></a></li><li class="interlanguage-link interwiki-hy mw-list-item"><a href="https://hy.wikipedia.org/wiki/%D4%BC%D5%A1%D5%A2%D5%A5%D5%BF%D5%A1%D5%AC%D5%B8%D5%AC" title="Լաբետալոլ (armenio)" lang="hy" hreflang="hy" data-title="Լաբետալոլ" data-language-autonym="Հայերեն" data-language-local-name="armenio" class="interlanguage-link-target"><span>Հայերեն</span></a></li><li class="interlanguage-link interwiki-it mw-list-item"><a href="https://it.wikipedia.org/wiki/Labetalolo" title="Labetalolo (italiano)" lang="it" hreflang="it" data-title="Labetalolo" data-language-autonym="Italiano" data-language-local-name="italiano" class="interlanguage-link-target"><span>Italiano</span></a></li><li class="interlanguage-link interwiki-nl mw-list-item"><a href="https://nl.wikipedia.org/wiki/Labetalol" title="Labetalol (neerlandés)" lang="nl" hreflang="nl" data-title="Labetalol" data-language-autonym="Nederlands" data-language-local-name="neerlandés" class="interlanguage-link-target"><span>Nederlands</span></a></li><li class="interlanguage-link interwiki-or mw-list-item"><a href="https://or.wikipedia.org/wiki/%E0%AC%B2%E0%AC%BE%E0%AC%AC%E0%AD%87%E0%AC%9F%E0%AC%BE%E0%AC%B2%E0%AD%8B%E0%AC%B2" title="ଲାବେଟାଲୋଲ (oriya)" lang="or" hreflang="or" data-title="ଲାବେଟାଲୋଲ" data-language-autonym="ଓଡ଼ିଆ" data-language-local-name="oriya" class="interlanguage-link-target"><span>ଓଡ଼ିଆ</span></a></li><li class="interlanguage-link interwiki-pl mw-list-item"><a href="https://pl.wikipedia.org/wiki/Labetalol" title="Labetalol (polaco)" lang="pl" hreflang="pl" data-title="Labetalol" data-language-autonym="Polski" data-language-local-name="polaco" class="interlanguage-link-target"><span>Polski</span></a></li><li class="interlanguage-link interwiki-pt mw-list-item"><a href="https://pt.wikipedia.org/wiki/Labetalol" title="Labetalol (portugués)" lang="pt" hreflang="pt" data-title="Labetalol" data-language-autonym="Português" data-language-local-name="portugués" class="interlanguage-link-target"><span>Português</span></a></li><li class="interlanguage-link interwiki-ro mw-list-item"><a href="https://ro.wikipedia.org/wiki/Labetalol" title="Labetalol (rumano)" lang="ro" hreflang="ro" data-title="Labetalol" data-language-autonym="Română" data-language-local-name="rumano" class="interlanguage-link-target"><span>Română</span></a></li><li class="interlanguage-link interwiki-ru mw-list-item"><a href="https://ru.wikipedia.org/wiki/%D0%9B%D0%B0%D0%B1%D0%B5%D1%82%D0%B0%D0%BB%D0%BE%D0%BB" title="Лабеталол (ruso)" lang="ru" hreflang="ru" data-title="Лабеталол" data-language-autonym="Русский" data-language-local-name="ruso" class="interlanguage-link-target"><span>Русский</span></a></li><li class="interlanguage-link interwiki-sh mw-list-item"><a href="https://sh.wikipedia.org/wiki/Labetalol" title="Labetalol (serbocroata)" lang="sh" hreflang="sh" data-title="Labetalol" data-language-autonym="Srpskohrvatski / српскохрватски" data-language-local-name="serbocroata" class="interlanguage-link-target"><span>Srpskohrvatski / српскохрватски</span></a></li><li class="interlanguage-link interwiki-simple mw-list-item"><a href="https://simple.wikipedia.org/wiki/Labetalol" title="Labetalol (Simple English)" lang="en-simple" hreflang="en-simple" data-title="Labetalol" data-language-autonym="Simple English" data-language-local-name="Simple English" class="interlanguage-link-target"><span>Simple English</span></a></li><li class="interlanguage-link interwiki-sr mw-list-item"><a href="https://sr.wikipedia.org/wiki/Labetalol" title="Labetalol (serbio)" lang="sr" hreflang="sr" data-title="Labetalol" data-language-autonym="Српски / srpski" data-language-local-name="serbio" class="interlanguage-link-target"><span>Српски / srpski</span></a></li><li class="interlanguage-link interwiki-sv mw-list-item"><a href="https://sv.wikipedia.org/wiki/Labetalol" title="Labetalol (sueco)" lang="sv" hreflang="sv" data-title="Labetalol" data-language-autonym="Svenska" data-language-local-name="sueco" class="interlanguage-link-target"><span>Svenska</span></a></li><li class="interlanguage-link interwiki-tr mw-list-item"><a href="https://tr.wikipedia.org/wiki/Labetalol" title="Labetalol (turco)" lang="tr" hreflang="tr" data-title="Labetalol" data-language-autonym="Türkçe" data-language-local-name="turco" class="interlanguage-link-target"><span>Türkçe</span></a></li><li class="interlanguage-link interwiki-uk mw-list-item"><a href="https://uk.wikipedia.org/wiki/%D0%9B%D0%B0%D0%B1%D0%B5%D1%82%D0%B0%D0%BB%D0%BE%D0%BB" title="Лабеталол (ucraniano)" lang="uk" hreflang="uk" data-title="Лабеталол" data-language-autonym="Українська" data-language-local-name="ucraniano" class="interlanguage-link-target"><span>Українська</span></a></li><li class="interlanguage-link interwiki-vi mw-list-item"><a href="https://vi.wikipedia.org/wiki/Labetalol" title="Labetalol (vietnamita)" lang="vi" hreflang="vi" data-title="Labetalol" data-language-autonym="Tiếng Việt" data-language-local-name="vietnamita" class="interlanguage-link-target"><span>Tiếng Việt</span></a></li><li class="interlanguage-link interwiki-zh mw-list-item"><a href="https://zh.wikipedia.org/wiki/%E6%8B%89%E8%B4%9D%E6%B4%9B%E5%B0%94" title="拉贝洛尔 (chino)" lang="zh" hreflang="zh" data-title="拉贝洛尔" data-language-autonym="中文" data-language-local-name="chino" class="interlanguage-link-target"><span>中文</span></a></li> </ul> <div class="after-portlet after-portlet-lang"><span class="wb-langlinks-edit wb-langlinks-link"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q958087#sitelinks-wikipedia" title="Editar enlaces interlingüísticos" class="wbc-editpage">Editar enlaces</a></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Espacios de nombres"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-nstab-main" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Labetalol" title="Ver la página de contenido [c]" accesskey="c"><span>Artículo</span></a></li><li id="ca-talk" class="vector-tab-noicon mw-list-item"><a href="/wiki/Discusi%C3%B3n:Labetalol" rel="discussion" title="Discusión acerca de la página [t]" accesskey="t"><span>Discusión</span></a></li> </ul> </div> </div> <div id="vector-variants-dropdown" class="vector-dropdown emptyPortlet" > <input type="checkbox" id="vector-variants-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-variants-dropdown" class="vector-dropdown-checkbox " aria-label="Cambiar variante de idioma" > <label id="vector-variants-dropdown-label" for="vector-variants-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">español</span> </label> <div class="vector-dropdown-content"> <div id="p-variants" class="vector-menu mw-portlet mw-portlet-variants emptyPortlet" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> </div> </div> </div> </div> </nav> </div> <div id="right-navigation" class="vector-collapsible"> <nav aria-label="Vistas"> <div id="p-views" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-views" > <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-view" class="selected vector-tab-noicon mw-list-item"><a href="/wiki/Labetalol"><span>Leer</span></a></li><li id="ca-edit" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Labetalol&action=edit" title="Editar esta página [e]" accesskey="e"><span>Editar</span></a></li><li id="ca-history" class="vector-tab-noicon mw-list-item"><a href="/w/index.php?title=Labetalol&action=history" title="Versiones anteriores de esta página [h]" accesskey="h"><span>Ver historial</span></a></li> </ul> </div> </div> </nav> <nav class="vector-page-tools-landmark" aria-label="Página de herramientas"> <div id="vector-page-tools-dropdown" class="vector-dropdown vector-page-tools-dropdown" > <input type="checkbox" id="vector-page-tools-dropdown-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-vector-page-tools-dropdown" class="vector-dropdown-checkbox " aria-label="Herramientas" > <label id="vector-page-tools-dropdown-label" for="vector-page-tools-dropdown-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet" aria-hidden="true" ><span class="vector-dropdown-label-text">Herramientas</span> </label> <div class="vector-dropdown-content"> <div id="vector-page-tools-unpinned-container" class="vector-unpinned-container"> <div id="vector-page-tools" class="vector-page-tools vector-pinnable-element"> <div class="vector-pinnable-header vector-page-tools-pinnable-header vector-pinnable-header-unpinned" data-feature-name="page-tools-pinned" data-pinnable-element-id="vector-page-tools" data-pinned-container-id="vector-page-tools-pinned-container" data-unpinned-container-id="vector-page-tools-unpinned-container" > <div class="vector-pinnable-header-label">Herramientas</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-page-tools.pin">mover a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-page-tools.unpin">ocultar</button> </div> <div id="p-cactions" class="vector-menu mw-portlet mw-portlet-cactions emptyPortlet vector-has-collapsible-items" title="Más opciones" > <div class="vector-menu-heading"> Acciones </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="ca-more-view" class="selected vector-more-collapsible-item mw-list-item"><a href="/wiki/Labetalol"><span>Leer</span></a></li><li id="ca-more-edit" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Labetalol&action=edit" title="Editar esta página [e]" accesskey="e"><span>Editar</span></a></li><li id="ca-more-history" class="vector-more-collapsible-item mw-list-item"><a href="/w/index.php?title=Labetalol&action=history"><span>Ver historial</span></a></li> </ul> </div> </div> <div id="p-tb" class="vector-menu mw-portlet mw-portlet-tb" > <div class="vector-menu-heading"> General </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="t-whatlinkshere" class="mw-list-item"><a href="/wiki/Especial:LoQueEnlazaAqu%C3%AD/Labetalol" title="Lista de todas las páginas de la wiki que enlazan aquí [j]" accesskey="j"><span>Lo que enlaza aquí</span></a></li><li id="t-recentchangeslinked" class="mw-list-item"><a href="/wiki/Especial:CambiosEnEnlazadas/Labetalol" rel="nofollow" title="Cambios recientes en las páginas que enlazan con esta [k]" accesskey="k"><span>Cambios en enlazadas</span></a></li><li id="t-upload" class="mw-list-item"><a href="//commons.wikimedia.org/wiki/Special:UploadWizard?uselang=es" title="Subir archivos [u]" accesskey="u"><span>Subir archivo</span></a></li><li id="t-specialpages" class="mw-list-item"><a href="/wiki/Especial:P%C3%A1ginasEspeciales" title="Lista de todas las páginas especiales [q]" accesskey="q"><span>Páginas especiales</span></a></li><li id="t-permalink" class="mw-list-item"><a href="/w/index.php?title=Labetalol&oldid=154165896" title="Enlace permanente a esta versión de la página"><span>Enlace permanente</span></a></li><li id="t-info" class="mw-list-item"><a href="/w/index.php?title=Labetalol&action=info" title="Más información sobre esta página"><span>Información de la página</span></a></li><li id="t-cite" class="mw-list-item"><a href="/w/index.php?title=Especial:Citar&page=Labetalol&id=154165896&wpFormIdentifier=titleform" title="Información sobre cómo citar esta página"><span>Citar esta página</span></a></li><li id="t-urlshortener" class="mw-list-item"><a href="/w/index.php?title=Especial:Acortador_de_URL&url=https%3A%2F%2Fes.wikipedia.org%2Fwiki%2FLabetalol"><span>Obtener URL acortado</span></a></li><li id="t-urlshortener-qrcode" class="mw-list-item"><a href="/w/index.php?title=Especial:QrCode&url=https%3A%2F%2Fes.wikipedia.org%2Fwiki%2FLabetalol"><span>Descargar código QR</span></a></li> </ul> </div> </div> <div id="p-coll-print_export" class="vector-menu mw-portlet mw-portlet-coll-print_export" > <div class="vector-menu-heading"> Imprimir/exportar </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li id="coll-create_a_book" class="mw-list-item"><a href="/w/index.php?title=Especial:Libro&bookcmd=book_creator&referer=Labetalol"><span>Crear un libro</span></a></li><li id="coll-download-as-rl" class="mw-list-item"><a href="/w/index.php?title=Especial:DownloadAsPdf&page=Labetalol&action=show-download-screen"><span>Descargar como PDF</span></a></li><li id="t-print" class="mw-list-item"><a href="/w/index.php?title=Labetalol&printable=yes" title="Versión imprimible de esta página [p]" accesskey="p"><span>Versión para imprimir</span></a></li> </ul> </div> </div> <div id="p-wikibase-otherprojects" class="vector-menu mw-portlet mw-portlet-wikibase-otherprojects" > <div class="vector-menu-heading"> En otros proyectos </div> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> <li class="wb-otherproject-link wb-otherproject-commons mw-list-item"><a href="https://commons.wikimedia.org/wiki/Category:Labetalol" hreflang="en"><span>Wikimedia Commons</span></a></li><li id="t-wikibase" class="wb-otherproject-link wb-otherproject-wikibase-dataitem mw-list-item"><a href="https://www.wikidata.org/wiki/Special:EntityPage/Q958087" title="Enlace al elemento conectado del repositorio de datos [g]" accesskey="g"><span>Elemento de Wikidata</span></a></li> </ul> </div> </div> </div> </div> </div> </div> </nav> </div> </div> </div> <div class="vector-column-end"> <div class="vector-sticky-pinned-container"> <nav class="vector-page-tools-landmark" aria-label="Página de herramientas"> <div id="vector-page-tools-pinned-container" class="vector-pinned-container"> </div> </nav> <nav class="vector-appearance-landmark" aria-label="Apariencia"> <div id="vector-appearance-pinned-container" class="vector-pinned-container"> <div id="vector-appearance" class="vector-appearance vector-pinnable-element"> <div class="vector-pinnable-header vector-appearance-pinnable-header vector-pinnable-header-pinned" data-feature-name="appearance-pinned" data-pinnable-element-id="vector-appearance" data-pinned-container-id="vector-appearance-pinned-container" data-unpinned-container-id="vector-appearance-unpinned-container" > <div class="vector-pinnable-header-label">Apariencia</div> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-pin-button" data-event-name="pinnable-header.vector-appearance.pin">mover a la barra lateral</button> <button class="vector-pinnable-header-toggle-button vector-pinnable-header-unpin-button" data-event-name="pinnable-header.vector-appearance.unpin">ocultar</button> </div> </div> </div> </nav> </div> </div> <div id="bodyContent" class="vector-body" aria-labelledby="firstHeading" data-mw-ve-target-container> <div class="vector-body-before-content"> <div class="mw-indicators"> </div> <div id="siteSub" class="noprint">De Wikipedia, la enciclopedia libre</div> </div> <div id="contentSub"><div id="mw-content-subtitle"></div></div> <div id="mw-content-text" class="mw-body-content"><div class="mw-content-ltr mw-parser-output" lang="es" dir="ltr"><style data-mw-deduplicate="TemplateStyles:r157776694">.mw-parser-output .infobox .imagen{max-width:100%;margin:0 auto}.mw-parser-output .infobox .imagen img{max-width:100%;height:auto}.mw-parser-output .infobox .mw-kartographer-container .thumbinner,.mw-parser-output .infobox .mw-kartographer-map{box-sizing:border-box;width:100%!important}body.skin-timeless .mw-parser-output .infobox .imagen a.image>img{max-width:100%!important;height:auto!important}</style><table class="infobox" style="width:22.7em; line-height: 1.4em; text-align:left; padding:.23em;"><tbody><tr><th colspan="3" class="cabecera medicina" style="text-align:center;background-color:transparent;color:inherit;">Labetalol</th></tr><tr><td colspan="3" class="imagen" style="text-align:center;background:#eee;;"> <span typeof="mw:File"><a href="/wiki/Archivo:(%2B-)-Labetalol_Structural_Formula_V1.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/6c/%28%2B-%29-Labetalol_Structural_Formula_V1.svg/220px-%28%2B-%29-Labetalol_Structural_Formula_V1.svg.png" decoding="async" width="220" height="107" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/6c/%28%2B-%29-Labetalol_Structural_Formula_V1.svg/330px-%28%2B-%29-Labetalol_Structural_Formula_V1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/6c/%28%2B-%29-Labetalol_Structural_Formula_V1.svg/440px-%28%2B-%29-Labetalol_Structural_Formula_V1.svg.png 2x" data-file-width="561" data-file-height="274" /></a></span></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Nombre (<a href="/wiki/Uni%C3%B3n_Internacional_de_Qu%C3%ADmica_Pura_y_Aplicada" title="Unión Internacional de Química Pura y Aplicada">IUPAC</a>) sistemático</th></tr><tr><td colspan="3" style="text-align:center;style="> (<i>RS</i>)-2-hidroxi-5-{1-hidroxi-2-[(1-metil-3-fenilpropil)amino]ethil}benzamida</td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Identificadores</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/N%C3%BAmero_de_registro_CAS" title="Número de registro CAS">Número CAS</a></th><td colspan="2" style="background:#eee;;"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://webbook.nist.gov/cgi/cbook.cgi?ID=36894-69-6&Units=SI">36894-69-6</a></span></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/C%C3%B3digo_ATC" title="Código ATC">Código ATC</a></th><td colspan="2" style="background:#eee;;"> <a href="/wiki/Anexo:C%C3%B3digo_ATC_C07" title="Anexo:Código ATC C07">C07</a><span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.whocc.no/atc_ddd_index/?code=C07AG01">AG01</a></span></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/PubChem" title="PubChem">PubChem</a></th><td colspan="2" style="background:#eee;;"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=3869">3869</a></span></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a></th><td colspan="2" style="background:#eee;;"> <span class="reflink plainlinks nourlexpansion"><a rel="nofollow" class="external text" href="http://www.drugbank.ca/drugs/APRD01062">APRD01062</a></span></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Datos químicos</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/F%C3%B3rmula_molecular" title="Fórmula molecular">Fórmula</a></th><td colspan="2" style="background:#eee;;"> <a href="/wiki/Carbono" title="Carbono"><span style="color: rgb(000,000,000); font-weight: bold;">C</span></a><sub>19</sub><a href="/wiki/Hidr%C3%B3geno" title="Hidrógeno"><span style="color: rgb(154,154,154); font-weight: bold;">H</span></a><sub>24</sub><a href="/wiki/Nitr%C3%B3geno" title="Nitrógeno"><span style="color: rgb(000,000,255); font-weight: bold;">N</span></a><sub>2</sub><a href="/wiki/Ox%C3%ADgeno" title="Oxígeno"><span style="color: rgb(232,070,070); font-weight: bold;">O</span></a><sub>3</sub><sup> </sup></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Masa_molar" title="Masa molar">Peso mol.</a></th><td colspan="2" style="background:#eee;;"> 328.406 <a href="/wiki/Gramo" title="Gramo">g</a>/<a href="/wiki/Mol" title="Mol">mol</a></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Farmacocinética</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Biodisponibilidad" title="Biodisponibilidad">Biodisponibilidad</a></th><td colspan="2" style="background:#eee;;"> 90-100%</td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Uni%C3%B3n_a_prote%C3%ADna_plasm%C3%A1tica" title="Unión a proteína plasmática">Unión proteica</a></th><td colspan="2" style="background:#eee;;"> 50%</td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Metabolismo_de_f%C3%A1rmacos" title="Metabolismo de fármacos">Metabolismo</a></th><td colspan="2" style="background:#eee;;"> <a href="/wiki/H%C3%ADgado" title="Hígado">hepático</a></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Semivida_de_eliminaci%C3%B3n" title="Semivida de eliminación">Vida media</a></th><td colspan="2" style="background:#eee;;"> VO: 6-8 horas; IV: 5,5 horas</td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Excreci%C3%B3n" title="Excreción">Excreción</a></th><td colspan="2" style="background:#eee;;"> <p>Excretado por la orina, no </p> se elimina por <a href="/wiki/Hemodi%C3%A1lisis" title="Hemodiálisis">hemodiálisis</a></td></tr><tr><th colspan="3" style="text-align:center;background:#ddd;;">Datos clínicos</th></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/Categor%C3%ADas_farmacol%C3%B3gicas_en_el_embarazo" title="Categorías farmacológicas en el embarazo">Cat. embarazo</a></th><td colspan="2" style="background:#eee;;"> C<br /> Usado en la <a href="/wiki/Hipertensi%C3%B3n_inducida_por_el_embarazo" class="mw-redirect" title="Hipertensión inducida por el embarazo">HIE</a></td></tr><tr><th scope="row" style="text-align:left;background:#ddeeff;;"><a href="/wiki/V%C3%ADas_de_administraci%C3%B3n_de_f%C3%A1rmacos" title="Vías de administración de fármacos">Vías de adm.</a></th><td colspan="2" style="background:#eee;;"> oral, <a href="/wiki/Intravenosa" class="mw-redirect" title="Intravenosa">iv</a></td></tr><tr><td class="noprint" colspan="3" style="text-align:left;"><div class="plainlinks wikidata-link" style="font-size: 0.85em">[<a href="https://www.wikidata.org/wiki/Q958087" class="extiw" title="d:Q958087">editar datos en Wikidata</a>]</div></td></tr></tbody></table> <p>El <b>labetalol</b> es un <a href="/wiki/Alfa_bloqueador" title="Alfa bloqueador">alfa</a> y <a href="/wiki/Betabloqueador" title="Betabloqueador">betabloqueador</a> mixto, usado para el tratamiento de la <a href="/wiki/Hipertensi%C3%B3n_arterial" title="Hipertensión arterial">hipertensión arterial</a>.<sup id="cite_ref-pmid18505576_1-0" class="reference separada"><a href="#cite_note-pmid18505576-1"><span class="corchete-llamada">[</span>1<span class="corchete-llamada">]</span></a></sup>​ </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Química"><span id="Qu.C3.ADmica"></span>Química</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=1" title="Editar sección: Química"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>El labetalol posee <a href="/wiki/Estereoisomero" class="mw-redirect" title="Estereoisomero">estereoisomeros</a>.<sup id="cite_ref-pmid1687367_2-0" class="reference separada"><a href="#cite_note-pmid1687367-2"><span class="corchete-llamada">[</span>2<span class="corchete-llamada">]</span></a></sup>​ Es una mezcla <a href="/wiki/Racemico" class="mw-redirect" title="Racemico">racémica</a> de cuatro <a href="/wiki/Is%C3%B3mero" class="mw-redirect" title="Isómero">isómeros</a>. Dos de estos <a href="/wiki/Is%C3%B3mero" class="mw-redirect" title="Isómero">isómeros</a>, las formas (<i>S</i>,<i>S</i>) y (<i>R</i>,<i>S</i>) son inactivos. El tercer isómero, (<i>S</i>,<i>R</i>) es un potente bloqueador del receptor <a href="/wiki/Alfa_1_bloqueador" title="Alfa 1 bloqueador">α<sub>1</sub></a>. El cuarto isómero, el (<i>R</i>,<i>R</i>), es un <a href="/wiki/Beta_bloqueador" class="mw-redirect" title="Beta bloqueador">β bloqueador</a> no selectivo mixto y un antagonista selectivo del receptor <a href="/wiki/Receptor_adren%C3%A9rgico_alfa_1" title="Receptor adrenérgico alfa 1">Receptor adrenérgico alfa 1</a> </p><p>Este medicamento causa el bloqueo de los <a href="/wiki/Receptor_adren%C3%A9rgico" title="Receptor adrenérgico">receptores adrenérgicos</a>, lo que disminuye la resistencia vascular periférica, con una alteración marcada de la <a href="/wiki/Frecuencia_cardiaca" class="mw-redirect" title="Frecuencia cardiaca">frecuencia cardiaca</a> o la <a href="/wiki/Fracci%C3%B3n_de_eyecci%C3%B3n" title="Fracción de eyección">fracción de eyección</a>. La relación β:α como antagonistas es de aproximadamente 3:1.<sup id="cite_ref-katzung10_3-0" class="reference separada"><a href="#cite_note-katzung10-3"><span class="corchete-llamada">[</span>3<span class="corchete-llamada">]</span></a></sup>​<sup id="cite_ref-4" class="reference separada"><a href="#cite_note-4"><span class="corchete-llamada">[</span>4<span class="corchete-llamada">]</span></a></sup>​ </p> <div class="mw-heading mw-heading2"><h2 id="Indicación"><span id="Indicaci.C3.B3n"></span>Indicación</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=2" title="Editar sección: Indicación"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Para el tratamiento de la <a href="/wiki/Hipertensi%C3%B3n_inducida_por_el_embarazo" class="mw-redirect" title="Hipertensión inducida por el embarazo">hipertensión inducida por el embarazo</a> la cual con frecuencia está asociada a la aparición de <a href="/wiki/Preeclampsia" title="Preeclampsia">preeclampsia</a>.<sup id="cite_ref-5" class="reference separada"><a href="#cite_note-5"><span class="corchete-llamada">[</span>5<span class="corchete-llamada">]</span></a></sup>​ </p><p>También está indicado en para tratar la <a href="/wiki/Hipertensi%C3%B3n" class="mw-redirect" title="Hipertensión">hipertensión</a> crónica, del <a href="/wiki/Feocromocitoma" title="Feocromocitoma">feocromocitoma</a> y las <a href="/wiki/Crisis_hipertensiva" title="Crisis hipertensiva">crisis hipertensivas</a>.<sup id="cite_ref-katzung10_3-1" class="reference separada"><a href="#cite_note-katzung10-3"><span class="corchete-llamada">[</span>3<span class="corchete-llamada">]</span></a></sup>​ </p> <div class="mw-heading mw-heading2"><h2 id="Administración"><span id="Administraci.C3.B3n"></span>Administración</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=3" title="Editar sección: Administración"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>El labetalol está disponible en tabletas de 100, 200 y 300 mg y solución <a href="/wiki/Intravenoso" class="mw-redirect" title="Intravenoso">intravenoso</a> de 5 mg/ml. En adultos la dosis de inicio es de 100 mg dos veces al día, con un máximo de 2,4 g/día. En casos de emergencia puede ser más alto. Las dosis intravenosas de inician con 20 mg durante 2 minutos, las dosis adicionales de 40 mg y luego de 80 mg puede administrarse cada diez minutos, según sea necesario. Dosis adicionales de 80 mg pueden administrarse hasta un maxímo de 300 mg. Adicionalmente labetalol puede ser administrado por infusión intravenoso de 2 mg/minuto, hasta una dosis máxima de 300 mg. </p> <div class="mw-heading mw-heading2"><h2 id="Efectos_adversos">Efectos adversos</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=4" title="Editar sección: Efectos adversos"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Entre los efectos adverso se encuentran: </p> <ul><li><a href="/wiki/Somnolencia" title="Somnolencia">Somnolencia</a></li> <li><a href="/wiki/Cansancio" title="Cansancio">Fatiga</a></li> <li>Debilidad</li> <li><a href="/wiki/Insomnio" title="Insomnio">Insomnio</a></li> <li><a href="/wiki/Disfunci%C3%B3n_sexual" title="Disfunción sexual">Disfunción sexual</a></li> <li>Hormigueo del cuero cabelludo que cede al poco tiempo .</li> <li><a href="/w/index.php?title=Erupci%C3%B3n_medicamentosa&action=edit&redlink=1" class="new" title="Erupción medicamentosa (aún no redactado)">Erupción medicamentosa</a> similar al <a href="/wiki/Liquen_plano" title="Liquen plano">liquen plano</a><sup id="cite_ref-bolognia_6-0" class="reference separada"><a href="#cite_note-bolognia-6"><span class="corchete-llamada">[</span>6<span class="corchete-llamada">]</span></a></sup>​</li> <li>Un efecto raro pero potencialmente letal es el <a href="/wiki/S%C3%ADndrome_de_distr%C3%A9s_respiratorio_agudo" class="mw-redirect" title="Síndrome de distrés respiratorio agudo">distrés respiratorio</a>.</li></ul> <div class="mw-heading mw-heading2"><h2 id="Contraindicaciones">Contraindicaciones</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=5" title="Editar sección: Contraindicaciones"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>El labetalol tiene contraindicación absoluta en pacientes con <a href="/wiki/Asma" title="Asma">asma</a>, y una contraindicación relativa en pacientes con <a href="/wiki/EPOC" class="mw-redirect" title="EPOC">EPOC</a>, <a href="/wiki/Insuficiencia_card%C3%ADaca_congestiva" class="mw-redirect" title="Insuficiencia cardíaca congestiva">insuficiencia cardíaca congestiva</a>, cualquier tipo de <a href="/wiki/Arritmia_card%C3%ADaca" class="mw-redirect" title="Arritmia cardíaca">bloqueo cardíaco</a>, <a href="/wiki/Bradicardia" title="Bradicardia">bradicardia</a> y en el choque cardiogénico. </p> <div class="mw-heading mw-heading2"><h2 id="Estereoquímica"><span id="Estereoqu.C3.ADmica"></span>Estereoquímica</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=6" title="Editar sección: Estereoquímica"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>El Labetalol contiene dos centros estereogénicos y consta de cuatro estereoisómeros. Esta es una mezcla de (<i>R</i>,<i> R</i>)-, ( <i>S</i>,<i>R</i>)-, (<i>R</i>,<i>S</i>)- y la forma (<i>S</i>,<i>S</i>): </p> <table class="wikitable" style="text-align:center"> <tbody><tr class="hintergrundfarbe6"> <th colspan="2">Estereoisómeros de Labetalol </th></tr> <tr> <td><span typeof="mw:File"><a href="/wiki/Archivo:(RR)-Labetalol_Structural_Formula_V1.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/b/b7/%28RR%29-Labetalol_Structural_Formula_V1.svg/250px-%28RR%29-Labetalol_Structural_Formula_V1.svg.png" decoding="async" width="250" height="122" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/b/b7/%28RR%29-Labetalol_Structural_Formula_V1.svg/375px-%28RR%29-Labetalol_Structural_Formula_V1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/b/b7/%28RR%29-Labetalol_Structural_Formula_V1.svg/500px-%28RR%29-Labetalol_Structural_Formula_V1.svg.png 2x" data-file-width="561" data-file-height="274" /></a></span><br /><small> CAS-Nummer: 75659-07-3</small> </td> <td><span typeof="mw:File"><a href="/wiki/Archivo:(SS)-Labetalol_Structural_Formula_V1.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/0/06/%28SS%29-Labetalol_Structural_Formula_V1.svg/250px-%28SS%29-Labetalol_Structural_Formula_V1.svg.png" decoding="async" width="250" height="122" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/0/06/%28SS%29-Labetalol_Structural_Formula_V1.svg/375px-%28SS%29-Labetalol_Structural_Formula_V1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/0/06/%28SS%29-Labetalol_Structural_Formula_V1.svg/500px-%28SS%29-Labetalol_Structural_Formula_V1.svg.png 2x" data-file-width="561" data-file-height="274" /></a></span><br /><small> CAS-Nummer: 83167-24-2</small> </td></tr> <tr> <td><span typeof="mw:File"><a href="/wiki/Archivo:(RS)-Labetalol_Structural_Formula_V1.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/6/64/%28RS%29-Labetalol_Structural_Formula_V1.svg/250px-%28RS%29-Labetalol_Structural_Formula_V1.svg.png" decoding="async" width="250" height="122" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/64/%28RS%29-Labetalol_Structural_Formula_V1.svg/375px-%28RS%29-Labetalol_Structural_Formula_V1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/64/%28RS%29-Labetalol_Structural_Formula_V1.svg/500px-%28RS%29-Labetalol_Structural_Formula_V1.svg.png 2x" data-file-width="561" data-file-height="274" /></a></span><br /><small> CAS-Nummer: 83167-32-2</small> </td> <td><span typeof="mw:File"><a href="/wiki/Archivo:(SR)-Labetalol_Structural_Formula_V1.svg" class="mw-file-description"><img src="//upload.wikimedia.org/wikipedia/commons/thumb/2/2b/%28SR%29-Labetalol_Structural_Formula_V1.svg/250px-%28SR%29-Labetalol_Structural_Formula_V1.svg.png" decoding="async" width="250" height="122" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/2/2b/%28SR%29-Labetalol_Structural_Formula_V1.svg/375px-%28SR%29-Labetalol_Structural_Formula_V1.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/2/2b/%28SR%29-Labetalol_Structural_Formula_V1.svg/500px-%28SR%29-Labetalol_Structural_Formula_V1.svg.png 2x" data-file-width="561" data-file-height="274" /></a></span><br /><small> CAS-Nummer: 83167-31-1</small> </td></tr></tbody></table> <div class="mw-heading mw-heading2"><h2 id="Véase_también"><span id="V.C3.A9ase_tambi.C3.A9n"></span>Véase también</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=7" title="Editar sección: Véase también"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a href="/wiki/Propranolol" title="Propranolol">Propranolol</a></li></ul> <div class="mw-heading mw-heading2"><h2 id="Referencias">Referencias</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=8" title="Editar sección: Referencias"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <div class="listaref" style="-moz-column-count:2; -webkit-column-count:2; column-count:2; list-style-type: decimal;"><ol class="references"> <li id="cite_note-pmid18505576-1"><span class="mw-cite-backlink"><a href="#cite_ref-pmid18505576_1-0">↑</a></span> <span class="reference-text"><span id="CITAREFFahed_S,_Grum_DF,_Papadimos_TJ2008" class="citation publicación">Fahed S, Grum DF, Papadimos TJ (2008). <a rel="nofollow" class="external text" href="http://www.pssjournal.com/content/2//13">«Labetalol infusion for refractory hypertension causing severe hypotension and bradycardia: an issue of patient safety»</a>. <i>Patient Saf Surg</i> <b>2</b>: 13. <small><a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC2429901">2429901</a></small>. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/18505576">18505576</a></small>. <small><a href="/wiki/Digital_object_identifier" class="mw-redirect" title="Digital object identifier">doi</a>:<a rel="nofollow" class="external text" href="https://dx.doi.org/10.1186%2F1754-9493-2-13">10.1186/1754-9493-2-13</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3ALabetalol&rft.atitle=Labetalol+infusion+for+refractory+hypertension+causing+severe+hypotension+and+bradycardia%3A+an+issue+of+patient+safety&rft.au=Fahed+S%2C+Grum+DF%2C+Papadimos+TJ&rft.aulast=Fahed+S%2C+Grum+DF%2C+Papadimos+TJ&rft.date=2008&rft.genre=article&rft.jtitle=Patient+Saf+Surg&rft.pages=13&rft.volume=2&rft_id=http%3A%2F%2Fwww.pssjournal.com%2Fcontent%2F2%2F%2F13&rft_id=info%3Adoi%2F10.1186%2F1754-9493-2-13&rft_id=info%3Apmc%2F2429901&rft_id=info%3Apmid%2F18505576&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-pmid1687367-2"><span class="mw-cite-backlink"><a href="#cite_ref-pmid1687367_2-0">↑</a></span> <span class="reference-text"><span id="CITAREFRiva_E,_Mennini_T,_Latini_Rdiciembre_de_1991" class="citation publicación">Riva E, Mennini T, Latini R (diciembre de 1991). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_british-journal-of-pharmacology_1991-12_104_4/page/823">«The alpha- and beta-adrenoceptor blocking activities of labetalol and its RR-SR (50:50) stereoisomers»</a>. <i>Br. J. Pharmacol.</i> <b>104</b> (4): 823-8. <small><a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1908821">1908821</a></small>. <small><a href="/wiki/PubMed_Identifier" class="mw-redirect" title="PubMed Identifier">PMID</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pubmed/1687367">1687367</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3ALabetalol&rft.atitle=The+alpha-+and+beta-adrenoceptor+blocking+activities+of+labetalol+and+its+RR-SR+%2850%3A50%29+stereoisomers&rft.au=Riva+E%2C+Mennini+T%2C+Latini+R&rft.aulast=Riva+E%2C+Mennini+T%2C+Latini+R&rft.date=diciembre+de+1991&rft.genre=article&rft.issue=4&rft.jtitle=Br.+J.+Pharmacol.&rft.pages=823-8&rft.volume=104&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_british-journal-of-pharmacology_1991-12_104_4%2Fpage%2F823&rft_id=info%3Apmc%2F1908821&rft_id=info%3Apmid%2F1687367&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-katzung10-3"><span class="mw-cite-backlink">↑ <a href="#cite_ref-katzung10_3-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-katzung10_3-1"><sup><i><b>b</b></i></sup></a></span> <span class="reference-text"><span id="CITAREFKatzung,_Bertram_G.2006" class="citation libro">Katzung, Bertram G. (2006). <i>Basic and clinical pharmacology</i>. Nueva York: McGraw-Hill Medical. p. 170. <small><a href="/wiki/ISBN" title="ISBN">ISBN</a> <a href="/wiki/Especial:FuentesDeLibros/0-07-145153-6" title="Especial:FuentesDeLibros/0-07-145153-6">0-07-145153-6</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3ALabetalol&rft.au=Katzung%2C+Bertram+G.&rft.aulast=Katzung%2C+Bertram+G.&rft.btitle=Basic+and+clinical+pharmacology&rft.date=2006&rft.genre=book&rft.isbn=0-07-145153-6&rft.pages=170&rft.place=Nueva%26nbsp%3BYork&rft.pub=McGraw-Hill+Medical&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text"><span id="CITAREFD_A_Richards,_J_Tuckman,_and_B_N_Prichardoctubre_de_1976" class="citation publicación">D A Richards, J Tuckman, and B N Prichard (octubre de 1976). <a rel="nofollow" class="external text" href="https://archive.org/details/sim_british-journal-of-clinical-pharmacology_1976-10_3_5/page/849">«Assessment of alpha- and beta-adrenoceptor blocking actions of labetalol.»</a>. <i>Br J Clin Pharmacol</i> <b>3</b> (5): 849-855. <small><a href="/wiki/PubMed_Central" title="PubMed Central">PMC</a> <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1428931">1428931</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3ALabetalol&rft.atitle=Assessment+of+alpha-+and+beta-adrenoceptor+blocking+actions+of+labetalol.&rft.au=D+A+Richards%2C+J+Tuckman%2C+and+B+N+Prichard&rft.aulast=D+A+Richards%2C+J+Tuckman%2C+and+B+N+Prichard&rft.date=octubre+de+1976&rft.genre=article&rft.issue=5&rft.jtitle=Br+J+Clin+Pharmacol&rft.pages=849-855&rft.volume=3&rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_british-journal-of-clinical-pharmacology_1976-10_3_5%2Fpage%2F849&rft_id=info%3Apmc%2F1428931&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal" class="Z3988"><span style="display:none;"> </span></span></span> </li> <li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text"> <a rel="nofollow" class="external free" href="http://www.bnf.org/bnf/bnf/56/2488.htm?q=%22labetalol%22">http://www.bnf.org/bnf/bnf/56/2488.htm?q=%22labetalol%22</a> </span> </li> <li id="cite_note-bolognia-6"><span class="mw-cite-backlink"><a href="#cite_ref-bolognia_6-0">↑</a></span> <span class="reference-text"><span id="CITAREFShiohara_T,_Kano_Y2007" class="citation libro">Shiohara T, Kano Y (2007). «Lichen planus and lichenoid dermatoses». En Bolognia JL, ed. <i>Dermatology</i>. St. Louis: Mosby. p. 161. <small><a href="/wiki/ISBN" title="ISBN">ISBN</a> <a href="/wiki/Especial:FuentesDeLibros/1-4160-2999-0" title="Especial:FuentesDeLibros/1-4160-2999-0">1-4160-2999-0</a></small>.</span><span title="ctx_ver=Z39.88-2004&rfr_id=info%3Asid%2Fes.wikipedia.org%3ALabetalol&rft.atitle=Dermatology&rft.au=Shiohara+T%2C+Kano+Y&rft.aulast=Shiohara+T%2C+Kano+Y&rft.btitle=Lichen+planus+and+lichenoid+dermatoses&rft.date=2007&rft.genre=bookitem&rft.isbn=1-4160-2999-0&rft.pages=161&rft.place=St.+Louis&rft.pub=Mosby&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook" class="Z3988"><span style="display:none;"> </span></span></span> </li> </ol></div> <div class="mw-heading mw-heading2"><h2 id="Enlaces_externos">Enlaces externos</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Labetalol&action=edit&section=9" title="Editar sección: Enlaces externos"><span>editar</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="https://www.drugs.com/mtm/labetalol.html">Labetalol - Información al consumidor en drugs.com</a>(en inglés)</li></ul> <style data-mw-deduplicate="TemplateStyles:r161257576">.mw-parser-output .mw-authority-control{margin-top:1.5em}.mw-parser-output .mw-authority-control .navbox table{margin:0}.mw-parser-output .mw-authority-control .navbox hr:last-child{display:none}.mw-parser-output .mw-authority-control .navbox+.mw-mf-linked-projects{display:none}.mw-parser-output .mw-authority-control .mw-mf-linked-projects{display:flex;padding:0.5em;border:1px solid var(--border-color-base,#a2a9b1);background-color:var(--background-color-neutral,#eaecf0);color:var(--color-base,#202122)}.mw-parser-output .mw-authority-control .mw-mf-linked-projects ul li{margin-bottom:0}.mw-parser-output .mw-authority-control .navbox{border:1px solid 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.mw-parser-output .mw-authority-control .mw-mf-linked-projects{border:1px solid var(--border-color-base,#72777d)!important;background-color:var(--background-color-neutral,#27292d)!important;color:var(--color-base,#eaecf0)!important}html.skin-theme-clientpref-os .mw-parser-output .mw-authority-control .navbox{border:1px solid var(--border-color-base,#72777d)!important;background-color:var(--background-color-neutral-subtle,#202122)!important}html.skin-theme-clientpref-os .mw-parser-output .mw-authority-control .navbox-list{border-color:#202122!important}html.skin-theme-clientpref-os .mw-parser-output .mw-authority-control .navbox th{background-color:#27292d!important}}</style><div class="mw-authority-control"><div role="navigation" class="navbox" aria-label="Navbox" style="width: inherit;padding:3px"><table class="hlist navbox-inner" style="border-spacing:0;background:transparent;color:inherit"><tbody><tr><th scope="row" class="navbox-group" style="width: 12%; text-align:center;"><a href="/wiki/Control_de_autoridades" title="Control de autoridades">Control de autoridades</a></th><td class="navbox-list navbox-odd" style="text-align:left;border-left-width:2px;border-left-style:solid;width:100%;padding:0px"><div style="padding:0em 0.25em"> <ul><li><b>Proyectos Wikimedia</b></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikidata" title="Wikidata"><img alt="Wd" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/20px-Wikidata-logo.svg.png" decoding="async" width="20" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/30px-Wikidata-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/40px-Wikidata-logo.svg.png 2x" data-file-width="1050" data-file-height="590" /></a></span> Datos:</span> <span class="uid"><a href="https://www.wikidata.org/wiki/Q958087" class="extiw" title="wikidata:Q958087">Q958087</a></span></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikimedia_Commons" title="Commonscat"><img alt="Commonscat" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> Multimedia:</span> <span class="uid"><span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Labetalol">Labetalol</a></span> / <span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Special:MediaSearch?type=image&search=%22Q958087%22">Q958087</a></span></span></li></ul> <hr /> <ul><li><b>Identificadores médicos</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/Medical_Subject_Headings" title="Medical Subject Headings">MeSH</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://meshb.nlm.nih.gov/record/ui?ui=D007741">D007741</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Descriptores_en_Ciencias_de_la_Salud" title="Descriptores en Ciencias de la Salud">DeCS</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://decs.bvsalud.org/en/ths/resource/?id=7918">7918</a></span></li> <li><span style="white-space:nowrap;">UMLS:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://ncim-stage.nci.nih.gov/ncimbrowser/ConceptReport.jsp?dictionary=NCI%20Metathesaurus&code=C0022860">C0022860</a></span></li> <li><b>Identificadores químicos</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/N%C3%BAmero_CAS" class="mw-redirect" title="Número CAS">Número CAS</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=36894-69-6">36894-69-6</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/EINECS" class="mw-redirect" title="EINECS">Números EINECS</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://echa.europa.eu/information-on-chemicals/ec-inventory/-/dislist/details/253-258-3">253-258-3</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/C%C3%B3digo_ATC" title="Código ATC">Código ATC</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.whocc.no/atc_ddd_index/?code=C07AG01">C07AG01</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/ChEBI" title="ChEBI">ChEBI</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:6343">6343</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/ChEMBL" title="ChEMBL">ChEMBL</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembl/compound_report_card/CHEMBL429/">CHEMBL429</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/ChemSpider" title="ChemSpider">ChemSpider</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.3734.html">3734</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/DrugBank" title="DrugBank">DrugBank</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://go.drugbank.com/drugs/DB00598">DB00598</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/PubChem" title="PubChem">PubChem</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/3869">3869</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/Unique_Ingredient_Identifier" class="mw-redirect" title="Unique Ingredient Identifier">UNII</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://gsrs.ncats.nih.gov/ginas/app/beta/substances/R5H8897N95">R5H8897N95</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/KEGG" title="KEGG">KEGG</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.kegg.jp/entry/C07063">C07063</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/SMILES" title="SMILES">SMILES</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.simolecule.com/cdkdepict/depict/bow/svg?smi=CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O&zoom=2.0&annotate=cip">ID</a></span></li> <li><span style="white-space:nowrap;"><a href="/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://chemapps.stolaf.edu/jmol/jmol.php?&model=InChI=1S/C19H24N2O3/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24)">ID</a></span></li> <li><span style="white-space:nowrap;">InChI key:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=%22SGUAFYQXFOLMHL-UHFFFAOYSA-N%22%5BInChIKey%5D">ID</a></span></li> <li><b>Identificadores biológicos</b></li> <li><span style="white-space:nowrap;"><a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>:</span> <span class="uid"><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=36894-69-6">36894-69-6</a></span></li></ul> </div></td></tr></tbody></table></div><div class="mw-mf-linked-projects hlist"> <ul><li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikidata" title="Wikidata"><img alt="Wd" src="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/20px-Wikidata-logo.svg.png" decoding="async" width="20" height="11" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/30px-Wikidata-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/f/ff/Wikidata-logo.svg/40px-Wikidata-logo.svg.png 2x" data-file-width="1050" data-file-height="590" /></a></span> Datos:</span> <span class="uid"><a href="https://www.wikidata.org/wiki/Q958087" class="extiw" title="wikidata:Q958087">Q958087</a></span></li> <li><span style="white-space:nowrap;"><span typeof="mw:File"><a href="/wiki/Wikimedia_Commons" title="Commonscat"><img alt="Commonscat" src="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/15px-Commons-logo.svg.png" decoding="async" width="15" height="20" class="mw-file-element" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/23px-Commons-logo.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/4/4a/Commons-logo.svg/30px-Commons-logo.svg.png 2x" data-file-width="1024" data-file-height="1376" /></a></span> Multimedia:</span> <span class="uid"><span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Category:Labetalol">Labetalol</a></span> / <span class="plainlinks"><a class="external text" href="https://commons.wikimedia.org/wiki/Special:MediaSearch?type=image&search=%22Q958087%22">Q958087</a></span></span></li></ul> </div></div> <!-- NewPP limit report Parsed by mw‐web.codfw.main‐f69cdc8f6‐nd6xd Cached time: 20241122182412 Cache expiry: 2592000 Reduced expiry: false Complications: [show‐toc] CPU time usage: 0.438 seconds Real time usage: 0.731 seconds Preprocessor visited node count: 3322/1000000 Post‐expand include size: 36608/2097152 bytes Template argument size: 1374/2097152 bytes Highest expansion depth: 24/100 Expensive parser function count: 17/500 Unstrip recursion depth: 0/20 Unstrip 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