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<div align="center"> <table border="0" width="700"> <tbody> <tr> <td height="21"> <div style="font-family: Arial, Helvetica, sans-serif; font-size: 12px;" align="center">If you are not able to view this e-mail properly, please <a href="http://www.worldpharmatoday.com/E-Newsletter/2017/week45/" target="_blank" rel="noopener noreferrer">click here</a> to view it online</div> </td> </tr> </tbody> </table> <table border="1" width="700" align="center"> <tbody> <tr> <td> <table border="0" width="100%" cellpadding="10px;" align="center"> <tbody> <tr> <td style="line-height: 0px;" width="30%"><a href="http://www.worldpharmatoday.com/" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/WPTLogo.jpg" alt="World Pharma Today Maqazine" width="145" height="65" border="0" /></a></td> <td width="70%"> <table border="0" width="80%" align="right"> <tbody> <tr> <td style="line-height: 0px;" width="54"><a href="https://www.linkedin.com/company/world-pharma-today?trk=biz-companies-cym" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/comman_images/worldpharmatoday_linkedin.png" alt="World Pharma Today Linkedin Page" /></a></td> <td style="line-height: 0px;" width="54"><a href="https://www.facebook.com/WorldPharmaToday/" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/comman_images/worldpharmatoday_facebook.jpg" alt="World Pharma Today Facebook Page" /></a></td> <td style="line-height: 0px;" width="91"><a href="https://twitter.com/worldpharma2day" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/comman_images/worldpharmatoday_twitter.png" alt="World Pharma Today Twitter Page" /></a></td> <td style="background-color: #0077bb; 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padding-bottom: 10px; text-align: center;"><a title="Cryoport" href="http://www.cryoport.com/" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/nBanners/Cryoport-_728x90.gif" alt="Cryoport" width="728" height="90" /></a></a></td> </tr> </tbody> </table> <table width="100%" border="0" style="background-color: #e6e5ed;"> <tbody> <tr> <td width="5%"></td> <td width="39%"> <table width="100%" border="0"> <tbody> <tr> <td width="5%" style="line-height: 0px;"> </td> <td width="95%" style="font-size: 23px; font-family: Arial;color:#00F"><strong>View Latest Issue of <br /> World Pharma Today <br /> November 2017 <a style="color: #00F;" href="http://en.calameo.com/read/0051605001172b9c2a0c9" target="_blank">e-book</a></strong></td> </tr> </tbody> </table> <p style="font-size: 16px; font-family: arial; font-weight: bold;"><br> <br> </p> <div align="center"></div></td> <td width="5%"></td> <td width="46%" style="padding-top: 10px; padding-bottom: 10px;"><div align="center"><a href="http://en.calameo.com/read/0051605001172b9c2a0c9" target="_blank"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/2017/Week-44/wpt-magazine.jpg" width="188" height="250" /></a></div></td> <td width="5%"></td> </tr> </tbody> </table> <table border="0" width="100%" cellpadding="0px" align="center" bgcolor="#0077BB"> <tbody> <tr> <td style="width: 5%;"> </td> <td style="line-height: 0px; width: 5%;"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/comman_images/7.png" alt="" width="" height="" /></td> <td style="color: #ffffff; font-size: 24px; font-family: Arial,Helvetica,sans-serif; width: 85%;">Top Latest Press Releases</td> <td style="width: 5%;"> </td> </tr> </tbody> </table> <table border="0" width="100%" align="center"> <tbody> <tr> <td width="5%"> </td> <td width="42%"> <div align="center"><a title="SOTIO Completes Enrolment of Phase III " href="http://www.worldpharmatoday.com/News/sotio-completes-enrolment-of-phase-iii-viable-study-in-late-stage-prostate-cancer" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/2017/week_45/sotio3.jpg" alt="SOTIO Completes Enrolment of Phase III " width="280" height="200" /></a></div> </td> <td width="6%"> </td> <td width="42%"> <p style="font-size: 16px; font-family: Arial,Helvetica,sans-serif; font-weight: bold;">SOTIO Completes Enrolment of Phase III VIABLE Study in Late Stage Prostate Cancer</p> <p style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; line-height: 18px; text-align: left; color: #666;">SOTIO, a biotechnology company owned by the PPF Group, today announced the enrolment of the last patient into the VIABLE study, a global Phase III clinical trial evaluating DCVAC/PCa in combination...</p> <table style="margin-bottom: 15px;" border="0" width="120px" cellspacing="0" cellpadding="0" align="left"> <tbody> <tr> <td style="background-color: #07b; font-family: Arial,Helvetica,sans-serif; color: #8affff; font-size: 12px; text-align: center; padding: 8px; font-weight: bold; text-transform: uppercase;"><a style="color: #ffffff; text-decoration: none; font-family: Arial, Helvetica, sans-serif;" title="SOTIO Completes Enrolment of Phase III" href="http://www.worldpharmatoday.com/News/sotio-completes-enrolment-of-phase-iii-viable-study-in-late-stage-prostate-cancer" target="_blank" rel="noopener noreferrer">READ MORE</a></td> </tr> </tbody> </table> </td> <td width="5%"> </td> </tr> </tbody> </table> <table border="0" width="100%" align="center"> <tbody> <tr> <td><hr /></td> </tr> </tbody> </table> <table border="0" width="100%" align="center"> <tbody> <tr> <td width="5%"> </td> <td width="42%"> <p style="font-size: 16px; font-family: Arial,Helvetica,sans-serif; font-weight: bold;"><span style="color: #000000; font-size: 16px; font-family: arial;">Lonza announces new offering of silensomes HLM for Drug metabolism studies</span></p> <p style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; line-height: 18px; text-align: left; color: #666;">Lonza Walkersville announced its new offering of Silensomes Human Liver Microsomes (HLM) products pooled human liver microsomes for in vitro cytochrome P450 (CYP) phenotyping.</p> <table style="margin-bottom: 15px;" border="0" width="120" cellspacing="0" cellpadding="0" align="left"> <tbody> <tr> <td style="background-color: #07b; font-family: Arial,Helvetica,sans-serif; color: #8affff; font-size: 12px; text-align: center; padding: 8px; font-weight: bold; text-transform: uppercase;"><a style="color: #ffffff; text-decoration: none;" title="Lonza announces new offering of silensomes HLM for Drug metabolism" href="http://www.worldpharmatoday.com/News/lonza-announces-new-offering-of-silensomes-hlm-for-drug-metabolism-studies" target="_blank" rel="noopener noreferrer">READ MORE</a></td> </tr> </tbody> </table> </td> <td width="6%"> </td> <td width="42%"> <p style="font-size: 16px; font-family: Arial,Helvetica,sans-serif; font-weight: bold;">CluePoints Builds on Late Phase work in Japan and Launches Risk-Based Monitoring Roadshow in Tokyo</p> <p style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; line-height: 18px; text-align: left; color: #666;">CluePoints, a leading provider of RBM and Data Quality Oversight solutions for clinical trials, has further expanded its Late Phase work in Japan by entering into two new partnerships with global top 20 pharma...</p> <table style="margin-bottom: 15px;" border="0" width="120px" cellspacing="0" cellpadding="0" align="left"> <tbody> <tr> <td style="background-color: #07b; font-family: Arial,Helvetica,sans-serif; color: #8affff; font-size: 12px; text-align: center; padding: 8px; font-weight: bold; text-transform: uppercase;"><a style="color: #ffffff; text-decoration: none;" title="CluePoints Builds on Late Phase work in Japan" href="http://www.worldpharmatoday.com/Press-Releases/cluepoints-builds-on-late-phase-work-in-japan-and-launches-risk-based-monitoring-roadshow-in-tokyo" target="_blank" rel="noopener noreferrer">READ MORE</a></td> </tr> </tbody> </table> </td> <td width="5%"> </td> </tr> </tbody> </table> <table border="0" width="100%" cellpadding="0px" align="center" bgcolor="#0077BB"> <tbody> <tr> <td style="width: 5%;"> </td> <td style="line-height: 0px; width: 5%;"><span style="line-height: 0px;"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/comman_images/6.png" alt="" width="" height="" /></span></td> <td style="color: #ffffff; font-size: 24px; font-family: Arial,Helvetica,sans-serif; width: 85%;"><span style="color: #fff; font-size: 24px; font-family: Arial, Helvetica, sans-serif;">Articles</span></td> <td style="width: 5%;"> </td> </tr> </tbody> </table> <table border="0" width="100%" align="center"> <tbody> <tr> <td width="5%"> </td> <td width="42%"> <div align="center"><a title="Time for a Different Approach to Quality Systems in Biopharmaceutical" href="http://www.worldpharmatoday.com/Articles/time-for-a-different-approach-to-quality-systems-in-biopharmaceutical-manufacturing" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/article/Weekly_newsletter/2017/week_45/Lonza_MODA.jpg" alt="Time for a Different Approach to Quality Systems in Biopharmaceutical " width="280" height="200" /></a></div> </td> <td width="6%"> </td> <td width="43%"> <p style="font-size: 16px; font-family: Arial,Helvetica,sans-serif; font-weight: bold;">Time for a Different Approach to Quality Systems in Biopharmaceutical Manufacturing</p> <p style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; line-height: 18px; text-align: left; color: #666;">Despite the wide array of information systems available for biopharmaceutical manufacturing, we need to adopt a follow-the-workflow approach to overcome the process inefficiencies generated by quality and production silos.</p> <table style="margin-bottom: 15px;" border="0" width="120px" cellspacing="0" cellpadding="0" align="left"> <tbody> <tr> <td style="background-color: #07b; font-family: Arial,Helvetica,sans-serif; color: #8affff; font-size: 12px; text-align: center; padding: 8px; font-weight: bold; text-transform: uppercase;"><a style="color: #ffffff; text-decoration: none;" title="Time for a Different Approach to Quality Systems in Biopharmaceutical" href="http://www.worldpharmatoday.com/Articles/time-for-a-different-approach-to-quality-systems-in-biopharmaceutical-manufacturing" target="_blank" rel="noopener noreferrer">READ MORE</a></td> </tr> </tbody> </table> </td> <td width="4%"> </td> </tr> </tbody> </table> <table border="0" width="100%" align="center"> <tbody> <tr> <td><hr /></td> </tr> </tbody> </table> <table border="0" width="100%" align="center"> <tbody> <tr> <td width="5%"> </td> <td width="42%"> <p style="font-size: 16px; font-family: Arial,Helvetica,sans-serif; font-weight: bold;"><span style="color: #000000; font-size: 16px; font-family: arial;">Direct-to-Patient Solutions Assuring Patient Participation and Retention in Clinical Trials</span></p> <p style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; line-height: 18px; text-align: left; color: #666;">The average cost of bringing a new drug to market is 2.6 billion dollars , according to a 2014 report published by Tufts Center for the Study of Drug Development. This is a rise of 145 percent, adjusted for inflation...</p> <table style="margin-bottom: 15px;" border="0" width="120" cellspacing="0" cellpadding="0" align="left"> <tbody> <tr> <td style="background-color: #07b; font-family: Arial,Helvetica,sans-serif; color: #8affff; font-size: 12px; text-align: center; padding: 8px; font-weight: bold; text-transform: uppercase;"><a style="color: #ffffff; text-decoration: none;" title="Direct-to-Patient Solutions" href="http://www.worldpharmatoday.com/Articles/direct-to-patient-solutions-assuring-patient-participation-and-retention-in-clinical-trials" target="_blank" rel="noopener noreferrer">READ MORE</a></td> </tr> </tbody> </table> </td> <td width="6%"> </td> <td width="43%"> <p style="font-size: 16px; font-family: Arial,Helvetica,sans-serif; font-weight: bold;">Asia increasing levels of clinical trial industry competition are to your benefit</p> <p style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; line-height: 18px; text-align: left; color: #666;">Biotechnology and pharmaceutical companies within the United States and Europe face an increasing number of hurdles when undertaking clinical trials within their own country or region problems such as over saturated patient聽pools, difficulties meeting and聽maintaining...</p> <table style="margin-bottom: 15px;" border="0" width="120px" cellspacing="0" cellpadding="0" align="left"> <tbody> <tr> <td style="background-color: #07b; font-family: Arial,Helvetica,sans-serif; color: #8affff; font-size: 12px; text-align: center; padding: 8px; font-weight: bold; text-transform: uppercase;"><a style="color: #ffffff; text-decoration: none;" title="Asia increasing levels of clinical trial" href="http://www.worldpharmatoday.com/Articles/asia-s-increasing-levels-of-clinical-trial-competition-are-to-your-benefit" target="_blank" rel="noopener noreferrer">READ MORE</a></td> </tr> </tbody> </table> </td> <td width="4%"> </td> </tr> </tbody> </table> <table border="0" width="100%" align="center" bgcolor="#0077BB"> <tbody> <tr> <td width="5%"> </td> <td style="color: #fff; font-family: Arial, Helvetica, sans-serif; font-size: 12px;" width="42%"> <p style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; color: #fff; margin-bottom: 5px; text-align: left;"><span style="font-weight: bold; font-size: 14px;">For Advertising Queries:</span><br /> <br /> <span style="font-family: Arial, Helvetica, sans-serif; font-size: 12px; color: #fff;"> Please e-mail : <a style="color: #fff;" href="mailto:kathryn@worldpharmatoday.com?subject=Reference%20World%20Pharma%20Today%20-%20weekly%20newsletter" target="_blank" rel="noopener noreferrer">kathryn@worldpharmatoday.com </a><br /> or <br /> call to: + 91 88268 49084 <br /> <br /> If you like to receive our latest <strong>Media Pack 2018</strong> / <strong>Editorial Calender</strong> please <a style="color: #ffffff;" href="mailto:kathryn@worldpharmatoday.com?subject=Reference%20World%20Pharma%20Today%20-%20weekly%20newsletter&body=I%20will%20be%20interested%20to%20in%20receiving%20the%20Mediapack%20for%202018%20and%20my%20details%20are%20as%20mentioned%20below.%20%0A%0D%0A%20Name%20%3A%0D%0A%20Company%20Name%20%3A%0D%0A%20Phone%20No%20%3A%0D%0A%20" target="_blank" rel="noopener noreferrer">click here</a></span></p> </td> <td width="6%"> </td> <td style="color: #fff; font-family: Arial, Helvetica, sans-serif; font-size: 12px;" width="42%"> <p align="left"><span style="font-family: Arial,Helvetica,sans-serif; font-size: 12px; color: #fff; margin-bottom: 5px; text-align: left; line-height: 20px;">For the latest visit: <a style="color: #ffffff; text-decoration: none;" title="World Pharma Today" href="http://www.worldpharmatoday.com/" target="_blank" rel="noopener noreferrer"><strong>www.worldpharmatoday.com</strong></a></span></p> <p align="left"><a href="http://www.worldpharmatoday.com/" target="_blank" rel="noopener noreferrer"><img src="http://www.worldpharmatoday.com/images/WPTLogo.jpg" alt="World Pharma Today" width="145" height="65" border="0" /></a></p> </td> <td width="5%"> </td> </tr> </tbody> </table> </td> </tr> </tbody> </table> </div>