Beyond the Basics: Addressing Obesity in Your Patients with Type 2 Diabetes - CME Information

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One-third of adults in the United States are considered obese, having a body mass index (BMI) ≥ 30 kg/m², according to the US Centers for Disease Control and Prevention. 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</li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/meetings" title="Meetings" target=""> Meetings</a> <ul class="sub_menu"> <li class="first"> <a class="all" href="/web/20131120232719/http://www.healio.com/endocrinology/meetings" title="News" target=""> Meetings/Courses</a> </li> <li class="first"> <a class="all" href="/web/20131120232719/http://www.healio.com/endocrinology/meetings/meeting-news-coverage" title="News" target=""> Meeting News Coverage</a> </li> </ul> </li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/careers" title="Careers" target=""> Careers</a> <ul class="sub_menu"> </ul> </li> </ul> <script type="text/javascript"> jQuery(".nav>li:last>a").addClass("last"); //fix for IE last-child style </script>   <div id="main-content-2col" class="tab-container">  <p id="breadcrumbs"> <a href="/web/20131120232719/http://www.healio.com/"> Healio</a> <span>›</span> <a href="/web/20131120232719/http://www.healio.com/endocrinology"> Endocrinology</a> <span>›</span> <a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab"> Education Lab/CME</a> </p>  <ul xmlns="http://www.w3.org/1999/xhtml" class="ed-lab-list">  <li class="img"><img src="/web/20131120232719im_/http://www.healio.com/~/media/Images/Education Lab/Covers/2013/07_July/J289.gif" alt="" width="83" height="106"/></li> <li><span class="cme-flag-med">CME</span></li> <li><h4>Beyond the Basics: Addressing Obesity in Your Patients with Type 2 Diabetes</h4>  <span class="earn-cme-btn"><a id="layout_0_maincontent_0_ctl00_EarnCMECreditLink" href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/posttest">Earn CME Credit »</a></span> </li> <li> <table cellspacing="0" cellpadding="0" border="0" width="650" style=""> <tbody> <tr> <td colspan="2"> <strong>Author(s)/Faculty: </strong> Robert H. Eckel, MD; Ralph A. DeFronzo, MD; Samuel Klein, MD; Steven R. Smith, MD </td> </tr> <tr> <td colspan="2"> <strong>Source: </strong> Healio - Endocrinology Education Lab </td> </tr> <tr> <td width="195"> <strong>Type: </strong> Multimedia </td> <td width="195"> <strong>Articles/Items: </strong> 5 </td> </tr> <tr> <td width="195"> <strong>Release Date: </strong> 9/13/2013 </td> <td width="195"> <strong>Expiration Date: </strong> 9/12/2014 </td> </tr> <tr> <td width="195"> <strong>Credit Type: </strong> CME </td> <td width="195"> <strong>Number of Credit(s): </strong> 2 </td> </tr> <tr> <td width="195" class="last"> <strong>Cost: </strong> Free </td> <td width="195" class="last"> Provider: <img src="/web/20131120232719im_/http://www.healio.com/~/media/Images/Education Lab/Provider Logos/VindicoLogo4web.gif" alt="Vindico Medical Education" width="77" height="19"/> </td> </tr> </tbody> </table> </li> <li class="overview" style="">Obesity has increased dramatically in the past 20 years, and is considered a healthcare epidemic in the United States. One-third of adults in the United States are considered obese, having a body mass index (BMI) ≥ 30 kg/m², according to the US Centers for Disease Control and Prevention. Serious health concerns associated with obesity include increased risk for hypertension, stroke, coronary heart disease, dyslipidemia, type 2 diabetes (T2DM), depression, sleep apnea, osteoarthritis, infertility, as well as cancers of the colon, breast, and endometrium. A BMI of ≥ 35 kg/m², increased waist circumference, and waist-to-hip ratio are predictors of increased risk for mortality. Particular challenges exist in the management of the obese patient with T2DM. Staying current with evidence-based recommendations for treatment, including knowledge of the safety and efficacy of emerging therapeutic options, is vital to healthcare practitioners as they work with patients to develop optimal, individualized, long-term strategies for overcoming obesity. This CME program will feature an interactive, audience driven case-based approach to address the association between obesity and T2DM, overcoming barriers to determine the appropriate strategy for managing overweight patients with diabetes, and safety, efficacy, and the appropriate use of newly approved medications to treat obesity.</li> <li class="sponsor">This activity is supported by an educational grant from Vivus.</li> </ul> <script type="text/javascript"> </script> <div class="cme-tab-group"> <ul id="layout_0_maincontent_1_ctl00_tabs" class="cme-tabs tabs"><li><a class="current" href="javascript:void(0)">CME Information</a></li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/pretest">Pretest</a></li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/defronzo-presentation">Dr. DeFronzo's Presentation</a></li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/smith-presentation">Dr. Smith's Presentation</a></li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/klein-presentation">Dr. Klein's Presentation</a></li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/case-choice">Case Choice</a></li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/educational-tools">Educational Tools</a></li> <li><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/posttest">Posttest</a></li> <li><a class="disabled" href="javascript:void(0)">Evaluation</a></li> </ul> </div> <div class="top-btnbox"><div class="earn-cme-btn"><a href="/web/20131120232719/http://www.healio.com/endocrinology/education-lab/2013/08_august/beyond-the-basics-addressing-obesity-in-your-patients-with-type-2-diabetes/posttest"></a></div><span class="login-note">You must be logged in to Healio.com to see this activity.</span><input type="submit" name="layout_0$maincontent_2$ctl10" value="" class="btnNext" align="right" style="margin:1px 0;"/></div> <a name="content"></a><div class="content"><p><strong><span style="text-decoration: underline;">Sponsorship Statement:</span></strong> This continuing medical education activity is sponsored by <img width="77" height="19" src="/web/20131120232719im_/http://www.healio.com/~/media/Images/Education Lab/Provider Logos/VindicoLogo4web.gif" alt="Vindico Medical Education"/>.</p> <p><strong><span style="text-decoration: underline;">Support Statement:</span></strong> This activity is supported by an educational grant from <img alt="" width="77" height="50" src="/web/20131120232719im_/http://www.healio.com/~/media/Images/Education Lab/Provider Logos/Vivus.jpg"/>.</p> <p><strong><span style="text-decoration: underline;">Target Audience</span></strong>: The intended audience for this activity is endocrinologists, diabetologists, certified diabetes educators, cardiologists, internal medicine physicians and other healthcare professionals involved in the treatment of obese patients.</p> <p><strong><span style="text-decoration: underline;">Learning Objectives: </span></strong> At the conclusion of this activity participants should be able to:</p> <ul> <li>Select patients for weight loss interventions based upon evidence-based criteria for defining and treating obesity.</li> <li>Incorporate effective treatment strategies for obese patients with multiple comorbidities.</li> <li>Define the physiological systems of signaling involved in controlling food intake and assess how they can be targeted through weight controlling drugs.</li> <li>Evaluate the safety and efficacy profiles of current and emerging anti-obesity medications to better select agents that improve adherence while enhancing weight loss. </li> </ul> <p><strong><span style="text-decoration: underline;">Course Chair: </span></strong><br/> <strong>Robert H. Eckel, MD<br/> </strong>Professor of Medicine<br/> Division of Endocrinology, Metabolism and Diabetes<br/> Division of Cardiology<br/> Professor of Physiology and Biophysics<br/> Charles A. Boettcher II Chair in Atherosclerosis<br/> University of Colorado Denver<br/> Director Lipid Clinic, University Hospital<br/> <em>Aurora, CO</em></p> <p><strong><span style="text-decoration: underline;">Faculty:</span></strong><br/> <strong>Ralph A. DeFronzo, MD<br/> </strong>Professor of Medicine<br/> Chief, Diabetes Division<br/> University of Texas Health Science Center of San Antonio<br/> Deputy Director<br/> Texas Diabetes Institute<br/> <em>San Antonio, TX</em></p> <p><strong></strong></p> <p><strong>Samuel Klein, MD<br/> </strong>William H. Danforth Professor of Medicine and Nutritional Science<br/> Director, Center for Human Nutrition<br/> Chief, Division of Geriatrics and Nutritional Science<br/> Medical Director, Weight Management Center<br/> Director, Center for Applied Research Sciences<br/> Washington University School of Medicine<br/> <em>St. Louis, MO</em></p> <p><strong>Steven R. Smith, MD<br/> </strong>Professor<br/> Diabetes and Obesity Research Center<br/> Sanford-Burnham Medical Research Institute<br/> Scientific Director<br/> Translational Research Institute for Metabolism and Diabetes<br/> Florida Hospital<br/> <em>Orlando, FL</em></p> <p><strong style="text-align: left;"><span style="text-decoration: underline;">External Reviewer:</span></strong><br/> Mark H. Schutta, MD</p> <p><strong style="text-align: left;"><span style="text-decoration: underline;">Accreditation:</span></strong><br/> Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.</p> <p><strong><span style="text-decoration: underline;">Credit Designation:</span></strong><br/> Vindico Medical Education designates this enduring material for a maximum of 2.0<em> AMA PRA Category 1 Credit(s)</em>™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.</p> <p>This enduring material is approved for 1 year from the date of original release, September 13, 2013 to September 12, 2014.</p> <p><strong style="text-align: left;"><span style="text-decoration: underline;">How To Participate in this Activity and Obtain CME Credit:</span></strong><br/> To participate in this CME activity, you must read the objectives, answer the pretest questions, watch the presentations, complete the CME posttest, and fill in the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 3 out of 4 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an <em>AMA PRA Category 1 Credit(s)</em>™ certificate.</p> <p><strong style="text-align: left;"><span style="text-decoration: underline;">Disclosures:</span></strong><br/> In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the <strong>relevant financial relationships</strong> of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. </p> <p><span style="text-align: left;">The authors disclose that they do have significant financial interests in any products or class of products discussed directly or indirectly in this activity, including research support.</span></p> <p style="text-align: justify;"><span style="text-decoration: underline;">Planning Committee and Faculty members report the following relationship(s):</span><br/> <strong>Ralph A. DeFronzo, MD           </strong><br/> <em>Consulting Fees:</em> Amylin, Bristol Myers Squibb, Janssen, Lexicon, Nova Nordisk, Takeda<br/> <em>Contracted Research:</em> Amylin, Bristol Myers Squibb, Lexicon, Takeda<br/> <em>Speakers Bureau:</em> Amylin, Astra Zeneca, Bristol Myers Squibb, Janssen, Nova Nordisk </p> <p style="text-align: justify;"><strong>Robert H. Eckel, MD    </strong><br/> <em>Salary:</em> University of Colorado Anschutz Medical Campus, Aurora, CO<br/> <em>Consulting Fees:</em> Amarin, Amylin, Eli Lilly, Esperion, Essentialis, Genentech, Genfit, Haptocure, Johnson & Johnson, Novo Nordisk, Regulus, Sanofi-Aventis, Vivus<br/> <em>Contracted Research:</em> GlaxoSmithKline<br/> <em>Other CME Sponsored Events:</em> AccelMed, Cardiometabolic Health Congress, CMEducation, Consensus Medical, National Jewish Hospital, VoxMed </p> <p style="text-align: justify;"><strong>Samuel Klein, MD        </strong><br/> <em>Research Support /Grants:</em> NIH, Egg Nutrition Council<br/> <em>Stock/Equity (any amount):</em> Aspire Bariatrics<br/> <em>Consulting/Employment:</em> Aspire Bariatrics, Vivus, Novo Nordisk, Takeda, Dannon-Yakult, ExpressScripts<br/> <em>Speakers Bureau/Honoraria:</em> Merck<br/> <em>Endowments:</em> Atkins Foundation, Kilo Foundation </p> <p style="text-align: justify;"><strong>Steven R. Smith, MD   </strong><br/> <em>Salary:</em> Florida Hospital<br/> <em>Consulting Fees:</em> Amylin, Arena, AstraZeneca, Boehringer Ingelheim, Bristol-Meyers Squibb, Eisai, Elcelyx, Eli Lilly, Five Prime Therapeutics, GlaxoSmithKline, NGM, Novo Nordisk, Orexigen Therapeutics, Piramal Life Sciences, Takeda, Zafgen<br/> <em>Ownership Interest</em>: Jenrin Discovery, Zafgen</p> <p><span style="text-decoration: underline;">External Reviewer reports the following relationship(s):</span><br/> <strong>Mark H. Schutta, MD   </strong><br/> No real or apparent conflicts of interest to report.</p> <p><span style="text-decoration: underline;">Vindico Medical Education staff report the following relationship(s):</span><br/> No relevant financial relationships to disclose.</p> <p><span style="text-align: left;">Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.</span></p> <p><strong style="text-align: left;"><span style="text-decoration: underline;">Unlabeled and Investigational Usage:</span></strong><br/> The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.</p> <p><strong style="text-align: left;"><span style="text-decoration: underline;">Copyright Statement:</span></strong><br/> Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2013. Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.</p> <p><strong> </strong></p> <br/> <div id="radePasteHelper" style="position: absolute; width: 1px; height: 1px; overflow: hidden; top: 0px; left: -10000px; border: 0px solid red;"><strong><span style="font-size: 10pt; text-decoration: underline; font-family: arial,sans-serif;">Sponsorship Statement:</span></strong><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span>This continuing medical education activity is sponsored by (INSERT VME LOGO). <o:p _rdeditor_exists="1"></o:p> <p><strong><span style="font-size: 10pt; text-decoration: underline; font-family: arial,sans-serif;"> </span></strong></p> <strong><span style="font-size: 10pt; text-decoration: underline; font-family: arial,sans-serif;">Support Statement:</span></strong> This activity is supported by an educational grant from (INSERT VIVUS LOGO).<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> <strong><span style="font-size: 10pt; text-decoration: underline; font-family: arial,sans-serif;">Target Audience</span></strong>: The intended audience for this activity is endocrinologists, diabetologists, certified diabetes educators, cardiologists, internal medicine physicians and other healthcare professionals involved in the treatment of obese patients.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNormal"><strong><span style="font-size: 10pt; text-decoration: underline; font-family: arial,sans-serif;"> </span></strong></p> Learning Objectives: <o:p _rdeditor_exists="1"></o:p>At the conclusion of this activity participants should be able to:<o:p _rdeditor_exists="1"></o:p><span style="font-size: 10pt; font-family: symbol;">·<span style="font-size: 7pt; font-family: 'times new roman';">        </span></span>Select patients for weight loss interventions based upon evidence-based criteria for defining and treating obesity.<o:p _rdeditor_exists="1"></o:p><span style="font-size: 10pt; font-family: symbol;">·<span style="font-size: 7pt; font-family: 'times new roman';">        </span></span>Incorporate effective treatment strategies for obese patients with multiple comorbidities.<o:p _rdeditor_exists="1"></o:p><span style="font-size: 10pt; font-family: symbol;">·<span style="font-size: 7pt; font-family: 'times new roman';">        </span></span>Define the physiological systems of signaling involved in controlling food intake and assess how they can be targeted through weight controlling drugs.<o:p _rdeditor_exists="1"></o:p><span style="font-size: 10pt; font-family: symbol;">·<span style="font-size: 7pt; font-family: 'times new roman';">        </span></span>Evaluate the safety and efficacy profiles of current and emerging anti-obesity medications to better select agents that improve adherence while enhancing weight loss.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Course Chair: <o:p _rdeditor_exists="1"></o:p>Robert H. Eckel, MD<o:p _rdeditor_exists="1"></o:p>Professor of Medicine<o:p _rdeditor_exists="1"></o:p>Division of Endocrinology, Metabolism and Diabetes<o:p _rdeditor_exists="1"></o:p>Division of Cardiology<o:p _rdeditor_exists="1"></o:p>Professor of Physiology and Biophysics<o:p _rdeditor_exists="1"></o:p>Charles A. Boettcher II Chair in Atherosclerosis<o:p _rdeditor_exists="1"></o:p>University of Colorado Denver <o:p _rdeditor_exists="1"></o:p>Director Lipid Clinic, University Hospital<o:p _rdeditor_exists="1"></o:p>Aurora, CO<o:p _rdeditor_exists="1"></o:p> <p class="MsoNormal"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Faculty:<o:p _rdeditor_exists="1"></o:p>Ralph A. DeFronzo, MD<o:p _rdeditor_exists="1"></o:p>Professor of Medicine<o:p _rdeditor_exists="1"></o:p>Chief, Diabetes Division<o:p _rdeditor_exists="1"></o:p>University of Texas Health Science Center of San Antonio<o:p _rdeditor_exists="1"></o:p>Deputy Director<o:p _rdeditor_exists="1"></o:p>Texas Diabetes Institute<o:p _rdeditor_exists="1"></o:p>San Antonio, TX<o:p _rdeditor_exists="1"></o:p><o:p _rdeditor_exists="1"> </o:p>Samuel Klein, MD<o:p _rdeditor_exists="1"></o:p>William H. Danforth Professor of Medicine and Nutritional Science<o:p _rdeditor_exists="1"></o:p>Director, Center for Human Nutrition<o:p _rdeditor_exists="1"></o:p>Chief, Division of Geriatrics and Nutritional Science<o:p _rdeditor_exists="1"></o:p>Medical Director, Weight Management Center<o:p _rdeditor_exists="1"></o:p>Director, Center for Applied Research Sciences<o:p _rdeditor_exists="1"></o:p>Washington University School of Medicine<o:p _rdeditor_exists="1"></o:p>St. Louis, MI<o:p _rdeditor_exists="1"></o:p> <p class="MsoNormal"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Steven R. Smith, MD<o:p _rdeditor_exists="1"></o:p>Professor<o:p _rdeditor_exists="1"></o:p>Diabetes and Obesity Research Center<o:p _rdeditor_exists="1"></o:p>Sanford-Burnham Medical Research Institute<o:p _rdeditor_exists="1"></o:p>Scientific Director<o:p _rdeditor_exists="1"></o:p>Translational Research Institute for Metabolism and Diabetes <o:p _rdeditor_exists="1"></o:p>Florida Hospital<o:p _rdeditor_exists="1"></o:p>Orlando, FL<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> External Reviewer:<o:p _rdeditor_exists="1"></o:p>Mark H. Schutta, MD<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Accreditation:<o:p _rdeditor_exists="1"></o:p>Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.<o:p _rdeditor_exists="1"></o:p>Credit Designation:<o:p _rdeditor_exists="1"></o:p>Vindico Medical Education designates this enduring material for a maximum of 2.0<em> AMA PRA Category 1 Credit(s)</em>™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.<o:p _rdeditor_exists="1"></o:p><o:p _rdeditor_exists="1"> </o:p>This enduring material is approved for 1 year from the date of original release, August 1, 2013 to August 1, 2014<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> How To Participate in this Activity and Obtain CME Credit:<o:p _rdeditor_exists="1"></o:p>To participate in this CME activity, you must read the objectives, answer the pretest questions, watch the presentations, complete the CME posttest, and fill in the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 3 out of 4 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an <em>AMA PRA Category 1 Credit(s)</em>™ certificate.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><strong><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></strong></p> Disclosures:<o:p _rdeditor_exists="1"></o:p>In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the <strong>relevant financial relationships</strong> of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. <o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> The authors disclose that they do have significant financial interests in any products or class of products discussed directly or indirectly in this activity, including research support.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Planning Committee and Faculty members report the following relationship(s):<o:p _rdeditor_exists="1"></o:p>Ralph A. DeFronzo, MD           <o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Consulting Fees:</span></em> Amylin, Bristol Myers Squibb, Janssen, Lexicon, Nova Nordisk, Takeda<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Contracted Research:</span></em> Amylin, Bristol Myers Squibb, Lexicon, Takeda<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Speakers Bureau:</span></em> Amylin, Astra Zeneca, Bristol Myers Squibb, Janssen, Nova Nordisk <o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><strong><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></strong></p> Robert H. Eckel, MD    <o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Salary:</span></em> University of Colorado Anschutz Medical Campus, Aurora, CO<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Consulting Fees:</span></em> Amarin, Amylin, Eli Lilly, Esperion, Essentialis, Genentech, Genfit, Haptocure, Johnson & Johnson, Novo Nordisk, Regulus, Sanofi-Aventis, Vivus<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Contracted Research:</span></em> GlaxoSmithKline<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Other CME Sponsored Events:</span></em> AccelMed, Cardiometabolic Health Congress, CMEducation, Consensus Medical, National Jewish Hospital, VoxMed <o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><strong><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></strong></p> Samuel Klein, MD        <o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Consulting Fees:</span></em> Aspire Bariatrics, Dannon/Yakult, Express Scripts, Novo Nordisk, Takeda, Vivus<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Fees for Non-CME Services Received Directly from Commercial Interest or their Agents:</span></em> Merck<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Ownership Interest:</span></em> Apire Bariatrics<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Other:</span></em> Atkins Foundation Charitable Trust, Kilo Foundation<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><strong><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></strong></p> Steven R. Smith, MD   <o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Salary:</span></em> Florida Hospital<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Consulting Fees:</span></em> Amylin, Arena, AstraZeneca, Boehringer Ingelheim, Bristol-Meyers Squibb, Eisai, Elcelyx, Eli Lilly, Five Prime Therapeutics, GlaxoSmithKline, NGM, Novo Nordisk, Orexigen Therapeutics, Piramal Life Sciences, Takeda, Zafgen<o:p _rdeditor_exists="1"></o:p><em><span style="font-size: 10pt; font-family: arial,sans-serif;">Ownership Interest</span></em>: Jenrin Discovery, Zafgen<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> External Reviewer reports the following relationship(s):<o:p _rdeditor_exists="1"></o:p>Mark H. Schutta, MD   <o:p _rdeditor_exists="1"></o:p>No real or apparent conflicts of interest to report.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Vindico Medical Education staff report the following relationship(s):<o:p _rdeditor_exists="1"></o:p>No relevant financial relationships to disclose.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Signed disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> Unlabeled and Investigational Usage:<o:p _rdeditor_exists="1"></o:p>The audience is advised that this continuing medical education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.<o:p _rdeditor_exists="1"></o:p> <p class="MsoNoSpacing"><span style="font-size: 10pt; font-family: arial,sans-serif;"> </span></p> <strong><span style="font-size: 10pt; text-decoration: underline; font-family: arial,sans-serif;">Copyright Statement:</span></strong><o:p _rdeditor_exists="1"></o:p>Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-994-9400; Fax: 856-384-6680. Printed in the USA. Copyright © 2013. Vindico Medical Education. All rights reserved. No part of this publication may be reproduced without written permission from the publisher. The material presented at or in any of Vindico Medical Education<span style="font-variant: small-caps;"> </span>continuing medical education activities does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. 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Beyond the Basics: Addressing Obesity in Your Patients with Type 2 Diabetes - CME Information | Endocrinology Education Lab