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Jean-Marie Lehn | Biography, Nobel Prize, & Facts | Britannica
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Please refer to the appropriate style manual or other sources if you have any questions. </div> <div class="label mt-20 mb-10">Select Citation Style</div> <select class="js-citation-format-select form-select"> <option selected value="mla">MLA</option> <option value="apa">APA</option> <option value="chicago">Chicago Manual of Style</option> </select> <div class="citation font-serif border rounded p-15 mt-20" data-authors="The Editors of Encyclopaedia Britannica" data-title="Jean-Marie Lehn" data-published-date="26 Sep. 2024" data-url="https://www.britannica.com/biography/Jean-Marie-Lehn" > <div class="citation-text"></div> </div> <button class="js-copy-citation-button mt-20 btn btn-xs btn-outline-blue border shadow-sm pr-10" > <em class="material-icons md-icon ml-n10 my-n5 mr-5" data-icon="file_copy"></em> <span class="js-citation-status-text">Copy Citation</span> </button> </div> </div> </div> <div> <button class="js-share-modal-button js-modal btn btn-sm btn-link gtm-topic-tool font-weight-bold btn-link" data-modal="[data-topic-id=335218] .md-share-modal"> <em class="material-icons mr-5 ml-n10 my-n5 md-icon" data-icon="share"></em> Share </button> <div class="md-share-modal size-lg d-none qa-share-modal"> <div class="md-modal-body"> <div class="h2 font-serif d-flex align-items-center pb-15 border-bottom"> <em class="material-icons text-blue mr-10" data-icon="share"></em> Share </div> <div class="label my-20">Share to social media</div> <div class="md-social-toolbar-circle d-flex align-items-start inverted" data-value="share" title="Jean-Marie Lehn" data-url="https://www.britannica.com/biography/Jean-Marie-Lehn" > <a class="social-icon facebook justify-content-center d-flex align-items-center align-self-center" data-provider="facebook" href="https://www.facebook.com/BRITANNICA/" target="_blank" rel="noopener"><span>Facebook</span></a> <a class="social-icon x justify-content-center d-flex align-items-center align-self-center" data-provider="x" href="https://x.com/britannica" target="_blank" rel="noopener"><span>X</span></a> </div> <div class="label pt-20 mt-20 mb-5 border-top">URL</div> <a class="font-serif text-truncate d-inline-block" href="https://www.britannica.com/biography/Jean-Marie-Lehn">https://www.britannica.com/biography/Jean-Marie-Lehn</a> </div> </div> </div> <div> <button class="js-feedback-modal-button js-modal btn btn-sm btn-link gtm-topic-tool font-weight-bold btn-link" data-modal=".md-feedback-modal"> <em class="material-icons mr-5 ml-n10 my-n5 md-icon" data-icon="message"></em> Feedback </button> </div> <div> <button class="qa-external-website-modal-button js-modal btn btn-sm btn-link gtm-topic-tool font-weight-bold btn-link" data-modal="[data-topic-id=335218] .md-websites-modal"> <em class="material-icons md-icon ml-n10 mr-5" data-icon="link"></em> External Websites </button> </div> </div> <div class="md-feedback-modal size-lg d-none"> <div class="md-modal-body"> <div class="h2 font-serif pb-15 border-bottom"> Feedback </div> <form method="post" action="/submission/feedback/335218"> <div class="my-20"> Corrections? 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They write new content and verify and edit content received from contributors.</div> </a> <div data-popper-arrow></div> </div> <span class="btn btn-link editor-link p-0 qa-byline-link gtm-byline font-12 byline-contributor text-decoration-underline"> The Editors of Encyclopaedia Britannica</span></div> <div class="last-updated font-12 font-serif"> <a class="byline-edit-history" href="https://www.britannica.com/biography/Jean-Marie-Lehn/additional-info#history" rel="nofollow">Article History</a> </div></div> </div> <button class="d-flex d-lg-none btn btn-outline-blue border rounded-sm shadow-sm mobile-toc-button gtm-mobile-toc-inline-button d-none d-sm-block js-sections-inline-button module-spacing btn d-lg-none"> <em class="material-icons mr-5 ml-n10 my-n5 md-icon" data-icon="toc"></em> Table of Contents </button> <div class="d-flex d-sm-none flex-row"> <button class="d-flex d-lg-none btn btn-outline-blue border rounded-sm shadow-sm mobile-toc-button gtm-mobile-toc-inline-button js-sections-inline-button module-spacing"> <em class="material-icons mr-5 ml-n10 my-n5 md-icon" data-icon="toc"></em> Table of Contents </button> <button class="ai-ask-button btn border-2 ai-ask-button btn border-2 module-spacing btn-sm js-inline-ai-ask-button btn-outline-red-400 border-red-400 p-10 ml-5"> Ask the Chatbot a Question </button> </div> <div class="js-qf-module qf-module px-40 px-sm-20 py-15 mx-auto module-spacing font-14 bg-gray-50 rounded"> <div class="qf-title font-weight-bold font-14 mb-10 text-center"> Quick Facts</div> <div class="facts-list mt-10"> <div class=""> <div class="js-fact mb-10 line-clamp clamp-3"> <dl> <dt>Born: </dt> <dd>September 30, 1939, Rosheim, <a href="/place/France">France</a> (age 85)</dd> </dl> <button class="js-more-btn d-none btn btn-unstyled font-12 bg-gray-50" aria-label="Toggle more/less fact data"> <em class="js-content link-blue">(Show more)</em> </button> </div> </div> <div class=""> <div class="js-fact mb-10 line-clamp clamp-3"> <dl> <dt>Awards And Honors: </dt> <dd><a href="/topic/Nobel-Prize">Nobel Prize (1987)</a></dd> </dl> <button class="js-more-btn d-none btn btn-unstyled font-12 bg-gray-50" aria-label="Toggle more/less fact data"> <em class="js-content link-blue">(Show more)</em> </button> </div> </div> <div class=""> <div class="js-fact mb-10 line-clamp clamp-3"> <dl> <dt>Subjects Of Study: </dt> <dd><a href="/science/chemical-synthesis">chemical synthesis</a></dd> <dd><a href="/science/crown-ether">crown ether</a></dd> </dl> <button class="js-more-btn d-none btn btn-unstyled font-12 bg-gray-50" aria-label="Toggle more/less fact data"> <em class="js-content link-blue">(Show more)</em> </button> </div> <div class="text-center"> <a class="btn btn-sm btn-link p-0" href="/facts/Jean-Marie-Lehn"> See all related content </a> </div> </div> </div> </div><!--[BEFORE-ARTICLE]--><span class="marker before-article"></span><section data-level="1" id="ref1"><!--[PREMOD1]--><span class="marker PREMOD1 mod-inline"></span><p class="topic-paragraph"><strong><span id="ref619468"></span>Jean-Marie Lehn</strong> (born September 30, 1939, Rosheim, France) is a French chemist who, together with <a href="https://www.britannica.com/biography/Charles-J-Pedersen" class="md-crosslink " data-show-preview="true">Charles J. Pedersen</a> and <a href="https://www.britannica.com/biography/Donald-J-Cram" class="md-crosslink " data-show-preview="true">Donald J. Cram</a>, was awarded the <a href="https://www.britannica.com/topic/Winners-of-the-Nobel-Prize-for-Chemistry-1846695" class="md-crosslink " data-show-preview="true">Nobel Prize for Chemistry</a> in 1987 for his contribution to the laboratory synthesis of molecules that mimic the vital chemical functions of molecules in living organisms.</p><!--[MOD1]--><span class="marker MOD1 mod-inline"></span><!--[PREMOD2]--><span class="marker PREMOD2 mod-inline"></span><p class="topic-paragraph">Lehn earned a Ph.D. in chemistry from the <a href="https://www.britannica.com/topic/University-of-Strasbourg" class="md-crosslink autoxref " data-show-preview="true">University of Strasbourg</a> in 1963, and in 1970 he became a professor of chemistry at Louis Pasteur University in <a href="https://www.britannica.com/place/Strasbourg" class="md-crosslink autoxref " data-show-preview="true">Strasbourg</a>. From 1979 to 2010 he was a professor at the <span id="ref1268318"></span><a href="https://www.britannica.com/topic/College-de-France" class="md-crosslink " data-show-preview="true">Collège de France</a> in Paris.</p><div class="one-good-fact-module"> </div><!--[MOD2]--><span class="marker MOD2 mod-inline"></span><!--[PREMOD3]--><span class="marker PREMOD3 mod-inline"></span><p class="topic-paragraph">Lehn expanded on Pedersen’s achievement in creating <span id="ref9827"></span><a href="https://www.britannica.com/science/crown-ether" class="md-crosslink ">crown ethers</a>, a class of two-dimensional ring-shaped organic <a class="md-dictionary-link md-dictionary-tt-off mw" data-term="compounds" href="https://www.merriam-webster.com/dictionary/compounds" data-type="MW">compounds</a> that are capable of selectively recognizing and combining with other molecules. In the course of his efforts to synthesize three-dimensional molecules that would possess similar reactive characteristics, Lehn created a molecule that combines with the chemical acetylcholine, which is an important neurotransmitter in the brain. His work raised the possibility of creating totally artificial <span id="ref9828"></span><a href="https://www.britannica.com/science/enzyme" class="md-crosslink " data-show-preview="true">enzymes</a> that would have characteristics superior to their natural counterparts in the <a href="https://www.britannica.com/science/human-body" class="md-crosslink autoxref " data-show-preview="true">human body</a>.</p><a class="link-module shadow-sm d-block qa-quiz-module" href="/quiz/faces-of-science" data-link-module-iframe-link=""> <img loading="lazy" src="https://cdn.britannica.com/88/144788-131-ADACA20E/Michael-Faraday-John-Frederic-Daniell.jpg" alt="Michael Faraday (L) English physicist and chemist (electromagnetism) and John Frederic Daniell (R) British chemist and meteorologist who invented the Daniell cell." class="rounded-sm mr-15" width="70" /> <div class="line-clamp clamp-5"> <div class="module-title bg-green">Britannica Quiz</div> <div class="font-weight-semi-bold mt-5">Faces of Science</div> </div> </a><!--[MOD3]--><span class="marker MOD3 mod-inline"></span></section> <span class="md-signature"><a href="/editor/The-Editors-of-Encyclopaedia-Britannica/4419">The Editors of Encyclopaedia Britannica</a></span><span class="md-signature">This article was most recently revised and updated by <a href="/contributor/encyclopaedia-britannica/12989892">Encyclopaedia Britannica</a>.</span><!--[END-OF-CONTENT]--><span class="marker end-of-content"></span><!--[AFTER-ARTICLE]--><span class="marker after-article"></span></div> <div id="chatbot-root"></div> </div> </div> </div> <div class="ai-dialog-placeholder"></div> </div> </div> <aside class="col-md-da-320"></aside> </div> </div> </div> </div> </article></div> </div></div> </div> </main> <div id="md-footer"></div> <noscript><iframe src="//www.googletagmanager.com/ns.html?id=GTM-5W6NC8" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript> <script type="text/javascript" id="_informizely_script_tag"> var IzWidget = IzWidget || {}; (function (d) { var scriptElement = d.createElement('script'); scriptElement.type = 'text/javascript'; scriptElement.async = true; scriptElement.src = "https://insitez.blob.core.windows.net/site/f780f33e-a610-4ac2-af81-3eb184037547.js"; var node = d.getElementById('_informizely_script_tag'); node.parentNode.insertBefore(scriptElement, node); } )(document); </script> <!-- Ortto ebmwprod capture code --> <script> window.ap3c = window.ap3c || {}; var ap3c = window.ap3c; ap3c.cmd = ap3c.cmd || []; ap3c.cmd.push(function() { ap3c.init('ZO4siT4cLwnykPnzZWJtd3Byb2Q', 'https://engage.email.britannica.com/'); ap3c.track({v: 0}); }); ap3c.activity = function(act) { ap3c.act = (ap3c.act || []); ap3c.act.push(act); }; var s, t; s = document.createElement('script'); s.type = 'text/javascript'; s.src = "https://engage.email.britannica.com/app.js"; t = document.getElementsByTagName('script')[0]; t.parentNode.insertBefore(s, t); </script> <script class="marketing-page-info" type="application/json"> {"pageType":"Topic","templateName":"DESKTOP","pageNumber":1,"pagesTotal":1,"pageId":335218,"pageLength":172,"initialLoad":true,"lastPageOfScroll":false} </script> <script class="marketing-content-info" type="application/json"> [] </script> <script src="https://cdn.britannica.com/mendel-resources/3-130/js/libs/jquery-3.5.0.min.js?v=3.130.38"></script> <script type="text/javascript" data-type="Init Mendel Code Splitting"> (function() { $.ajax({ dataType: 'script', cache: true, url: 'https://cdn.britannica.com/mendel-resources/3-130/dist/topic-page.js?v=3.130.38' }); })(); </script> <script class="analytics-metadata" type="application/json"> {"leg":"A","adLeg":"A","userType":"ANONYMOUS","pageType":"Topic","pageSubtype":null,"articleTemplateType":"BIO_SMALL","gisted":false,"pageNumber":1,"hasSummarizeButton":false,"hasAskButton":true} </script> <script type="text/javascript"> EBStat={accountId:-1,hostnameOverride:'webstats.eb.com',domain:'www.britannica.com', json:''}; </script> <script type="text/javascript"> ( function() { $.ajax( { dataType: 'script', cache: true, url: '//www.britannica.com/webstats/mendelstats.js?v=1' } ) .done( function() { try {writeStat(null,EBStat);} catch(err){} } ); })(); </script> <div id="bc-fixed-dialogue"></div> </body> </html>