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BrIDGs Frequently Asked Questions | National Center for Advancing Translational Sciences
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class="usa-breadcrumb__link"><span>Research</span></a> </li> <li class="usa-breadcrumb__list-item"> <a href="/research/research-activities" class="usa-breadcrumb__link"><span>Research Activities</span></a> </li> <li class="usa-breadcrumb__list-item"> <a href="/research/research-activities/bridgs" class="usa-breadcrumb__link"><span>Bridging Interventional Development Gaps (BrIDGs)</span></a> </li> <li class="usa-breadcrumb__list-item"> <a href="/research/research-activities/bridgs/work" class="usa-breadcrumb__link"><span>Work With BrIDGs</span></a> </li> <li class="usa-breadcrumb__list-item"> <span>BrIDGs Frequently Asked Questions</span> </li> </ol> </nav> </div> <div class="block block-layout-builder block-field-blocknodelanding-page-new-field-metatag"> </div> </div> </div> <div class="layout layout--onecol"> <div class="layout__region layout__region--content"> <div class="block block-layout-builder block-extra-field-blocknodelanding-page-new-content-moderation-control"> </div> <div 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data-drupal-link-system-path="node/27696">How to Request a BrIDGs Collaboration</a> </li> <li> <a href="/research/research-activities/bridgs/work/intellectual-property" data-drupal-link-system-path="node/28431">Intellectual Property and BrIDGs</a> </li> <li class="last"> <a href="/research/research-activities/bridgs/work/prior-proposals" class="last" data-drupal-link-system-path="node/28440">Updates to Prior BrIDGs Proposals</a> </li> </ul> </nav> </div> <section> <div class="container news-content Advancing"> <h2 class="section-heading">BrIDGs Frequently Asked Questions</h2> <div class="paragraph paragraph--type--body-content paragraph--view-mode--default"> <div class="contact-box"><h4>Contact</h4><p><a href="mailto:BrIDGs@mail.nih.gov?subject=BrIDGs%20Information" title="Email BrIDGs staff">BrIDGs Program staff</a></p></div><h3>How long is the collaboration decision process?</h3><p>The decision to collaborate on a proposed project is based on an internal assessment of scientific merit, programmatic fit and the availability of NIH funds. A final decision may take several months to coordinate.</p><h3>Is an active NIH grant required to be eligible for BrIDGs?</h3><p>No.</p><h3>Are <em>in vivo</em> efficacy data required before collaborating with the program?</h3><p>Data from the most relevant <em>in vivo</em> models available should be obtained before submitting a proposal. Efficacy should be demonstrated via the intended clinical route of administration and preferably be published in a peer-reviewed journal or independently replicated. If efficacy studies have been conducted by a route that differs from that proposed for initial clinical trials, then data on these different routes must be available to compare exposure levels in target organs.</p><h3>Am I required to reveal the chemical structure of the proposed compound in the proposal?</h3><p>Yes. NCATS staff and external experts must have access to the chemical structure to assess the scientific merit of the proposal.</p><h3>Can I out-license the proposed compound and continue to collaborate with BrIDGs?</h3><p>Yes. A compound may be licensed before, during or after working with BrIDGs. The principal investigator from the partnering organization will continue to serve as the point of contact for the project. The licensee is welcome to participate in project meetings and decisions with the permission of the principal investigator.</p><h3>How does BrIDGs handle confidentiality?</h3><p>Information provided to BrIDGs during the collaboration decision phase is considered confidential. 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