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data-blazy=""> <div class="field__item"> <div data-b-token="b-aa06d0075cd" class="media media--blazy media--bundle--image media--image media--responsive media--ratio media--ratio--32 is-b-loading"> <picture> <source srcset="about:blank" media="(min-width: 768px)" type="image/webp" width="950" height="633" data-srcset="/sites/depreterlab.sites.vib.be/files/styles/3_2_medium/public/2022-11/KatleenDePreter.png.webp?itok=6xVbQYeW 1x"/> <source srcset="about:blank" media="(min-width: 0px)" type="image/webp" width="768" height="512" data-srcset="/sites/depreterlab.sites.vib.be/files/styles/3_2_small/public/2022-11/KatleenDePreter.png.webp?itok=zwEWYxXL 1x"/> <img decoding="async" class="media__element b-lazy b-responsive" loading="auto" data-src="/sites/depreterlab.sites.vib.be/files/2022-11/KatleenDePreter.png" width="768" height="512" src="data:image/svg+xml;charset=utf-8,%3Csvg%20xmlns%3D'http%3A%2F%2Fwww.w3.org%2F2000%2Fsvg'%20viewBox%3D'0%200%201%201'%2F%3E" alt="Katleen De Preter" /> </picture> </div> </div> </div> </div> <div class="layout__item layout__item-text aos-init" data-aos=fade-left> <h2 class="field field--name-field-title field--type-string title field__item">Katleen De Preter</h2> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><ul><li>Senior Full Research Professor, BOF-ZAP, Ghent University, Belgium & VIB Group Leader, 2022-present</li><li>Full Research Professor, BOF-ZAP, Ghent University, Belgium, 2019-2022</li><li>Full Professor 10%, Ghent University, Belgium, 2014-2019</li><li>Associate Professor 10%, Ghent University, Belgium, 2011-2014</li><li>Postdoc: Ghent University, Belgium, 2004-2019</li><li>PhD: Ghent University, Belgium, 2004</li></ul><p>In 2000, Katleen De Preter obtained a Master in Bioscience Engineering (Major Cell and Gene Biotechnology) at Ghent University. During her PhD (FWO) and post-doctoral fellowship (IWT and FWO), she was involved in genomics profiling of neuroblastoma tumors aiming to identify new vulnerable markers for therapy and better biomarkers for prognosis and prediction. Since 2011, Katleen became part-time professor at the Department of Biomolecular Medicine (Ghent University) and started the research lab of Translational Onco-genomics and Bio-informatics. In 2019, she obtained a position as full professor with a BOF-ZAP grant. That same year, in May 2019, her work on biomarkers for neuroblastoma was rewarded with the Antoine Faes price. In 2022, she obtained an ERC consolidator grant for the “EpiGuide” project. <span>Katleen was one of the CRIG co-founders and has been the chairperson of the CRIG Steering Committee since late 2022.</span></p></div> <div class="field field--name-field-link field--type-link field--label-hidden btn-wrapper field__item"> <a href="mailto: katleen.depreter@vib-ugent.be" class="btn btn--dark btn--invert">Contact</a> </div> </div> </div> </div> <div class="block block--layout-builder block--inline-blocktext-one-col aos-init" data-aos=fade-down id="text-one-col-8c3"> <h2 class="field field--name-field-title field--type-string title field__item">Intro research focus</h2> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>The major research theme of our lab is the development of analytical and bio-informatic pipelines for diagnostic, prognostic and predictive analysis enabling precision oncology. An important challenge in precision oncology is the heterogeneity of the tumor, including intertumoral and intra-tumoral heterogeneity as well as spatial and temporal heterogeneity. We aim to develop novel tools that allow mapping of this (epi)genetic tumor heterogeneity, further aiding in patient management and therapy stratification. To this end we can rely on a unique expertise that is positioned at the interface between technological/bioinformatic development and clinical validation/implementation. The tumor (epi)genetic heterogeneity is investigated by analyzing tumor tissue samples as well as minimally-invasive liquid biopsy samples that enable longitudinal monitoring of the heterogeneity. Over the past years, we have optimized the processing of liquid biopsy samples for the analysis of (epi)genetic biomarkers and has gained expertise in computational deconvolution and single-cell omics data mining. Previous research projects have already resulted in new biomarkers for the pediatric cancer, neuroblastoma. More recently, we have also started working on other pediatric cancers and adult cancers (i.e., lung, prostate, esophageal cancer, amongst others).</p></div> </div> <div class="block block--layout-builder block--inline-blocklogos logo_large" id="logos-e5b"> <div class="layout slider-on"> <div class="layout__item"> <h2 class="field field--name-field-title field--type-string title field__item">Awards and or funding</h2> <div class="field field--name-field-logo field--type-entity-reference-revisions field--label-hidden field__items"> <div class="field__item"> <div class="paragraph paragraph--type--logo paragraph--view-mode--default" id="logo-d2b"> <div class="logo-wrapper"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <img src="https://depreterlab.sites.vib.be/sites/depreterlab.sites.vib.be/files/styles/logo_large/public/2021-07/OIP%20%282%29.jpeg.webp?itok=PwXuCEZ4" alt="logo" /> </div> <a class="logo-link" target="_blank" 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