CINXE.COM
New study shows NICE Advice support can reduce appraisal timelines by 3 months | NICE
<!DOCTYPE html><html lang="en-GB" prefix="og: http://ogp.me/ns#"><head><meta charSet="utf-8"/><meta name="twitter:card" content="summary"/><meta name="twitter:site" content="@NICEComms"/><meta name="twitter:creator" content="@NICEComms"/><meta property="og:url" content="https://www.nice.org.uk/news/articles/new-study-shows-nice-advice-support-can-reduce-appraisal-timelines-by-3-months"/><meta property="og:type" content="website"/><meta property="og:image" content="/open-graph/open-graph-1200x630.png"/><meta property="og:image:alt" content="Logo for NICE (The National Institute for Health and Care Excellence)"/><meta property="og:image:width" content="1200"/><meta property="og:image:height" content="630"/><meta property="og:image" content="/open-graph/open-graph-1200x1200.png"/><meta property="og:image:alt" content="Logo for NICE (The National Institute for Health and Care Excellence)"/><meta property="og:image:width" content="1200"/><meta property="og:image:height" content="1200"/><meta property="og:locale" content="en_GB"/><meta property="og:site_name" content="NICE website: The National Institute for Health and Care Excellence"/><meta name="viewport" content="width=device-width, initial-scale=1, shrink-to-fit=no"/><meta name="application-name" content="NICE"/><meta name="DC:Publisher" content="NICE"/><meta name="DC.Rights.Copyright" content="All content on this site is NICE copyright unless otherwise stated. You can download material for private research, study or in-house use only. Do not distribute or publish any material from this site without first obtaining NICE's permission. Where Crown copyright applies, see the Office of Public Sector Information (formerly HMSO) website for information."/><meta name="DC.Language" content="eng"/><meta name="x-country" content="gb"/><meta name="apple-mobile-web-app-capable" content="yes"/><meta name="apple-mobile-web-app-title" content="NICE"/><meta name="theme-color" content="#004650"/><meta name="msapplication-TileColor" content="#004650"/><meta http-equiv="x-ua-compatible" content="IE=edge; chrome=1"/><link rel="icon" href="/favicon.ico"/><link rel="icon" type="image/png" sizes="16x16" href="/icons/icon-16x16.png"/><link rel="icon" type="image/png" sizes="32x32" href="/icons/icon-32x32.png"/><link rel="apple-touch-icon" sizes="120x120" href="/icons/icon-120x120.png"/><link rel="apple-touch-icon" sizes="152x152" href="/icons/icon-152x152.png"/><link rel="apple-touch-icon" sizes="167x167" href="/icons/icon-167x167.png"/><link rel="apple-touch-icon" sizes="180x180" href="/icons/icon-180x180.png"/><link rel="mask-icon" color="black" href="/icons/safari-pinned-tab.svg"/><link rel="canonical" href="https://www.nice.org.uk/news/articles/new-study-shows-nice-advice-support-can-reduce-appraisal-timelines-by-3-months"/><title>New study shows NICE Advice support can reduce appraisal timelines by 3 months | NICE</title><meta name="robots" content="index,follow"/><meta property="og:title" content="New study shows NICE Advice support can reduce appraisal timelines by 3 months"/><meta name="DC.Issued" content="2024-11-14T07:49:45.669Z"/><meta name="DC.Modified" content="2024-11-14T09:58:42.160Z"/><meta name="next-head-count" content="41"/><link rel="preload" href="/_next/static/media/a34f9d1faa5f3315-s.p.woff2" as="font" type="font/woff2" crossorigin="anonymous" data-next-font="size-adjust"/><link rel="preload" href="/_next/static/media/3a8dc5763a8ae4b2-s.p.woff2" as="font" type="font/woff2" crossorigin="anonymous" data-next-font="size-adjust"/><link rel="preload" href="/_next/static/css/8c329cb8c6555bb3.css" as="style"/><link rel="stylesheet" href="/_next/static/css/8c329cb8c6555bb3.css" data-n-g=""/><link rel="preload" href="/_next/static/css/798f6cad441bd639.css" as="style"/><link rel="stylesheet" href="/_next/static/css/798f6cad441bd639.css" data-n-p=""/><noscript data-n-css=""></noscript><script defer="" nomodule="" src="/_next/static/chunks/polyfills-c67a75d1b6f99dc8.js"></script><script id="cookieBanner" src="https://cdn.nice.org.uk/cookie-banner/cookie-banner.min.js" defer="" data-nscript="beforeInteractive"></script><script src="/_next/static/chunks/webpack-a8152f522ffbca5f.js" defer=""></script><script src="/_next/static/chunks/framework-ca706bf673a13738.js" defer=""></script><script src="/_next/static/chunks/main-ea26e5a44792708e.js" defer=""></script><script src="/_next/static/chunks/pages/_app-beadde1d6848e8e5.js" defer=""></script><script src="/_next/static/chunks/1664-e3df72ec02461a64.js" defer=""></script><script src="/_next/static/chunks/9739-fea7e13096f95c6e.js" defer=""></script><script src="/_next/static/chunks/3217-2d46a8ada9951dd7.js" defer=""></script><script src="/_next/static/chunks/4969-94d4d9ccb221a8e2.js" defer=""></script><script src="/_next/static/chunks/pages/news/articles/%5Bslug%5D-773f44e4c75d9978.js" defer=""></script><script src="/_next/static/nPtE9ZhzdAiprqYEkzKqu/_buildManifest.js" defer=""></script><script src="/_next/static/nPtE9ZhzdAiprqYEkzKqu/_ssgManifest.js" defer=""></script></head><body><div id="__next"><div class="__variable_d48d41 __variable_d65c78"><div><span id="scrim" aria-hidden="true"></span><div class="Header_header__xWXlb" data-tracking="Global nav" id="top"><header aria-label="Site header"><ul class="Header_a11yLinks__8L7qW" aria-label="Accessibility links"><li><a href="#content-start" class="SkipLink_link__RWkQR">Skip to content</a></li><li><a href="https://www.nice.org.uk/accessibility" class="SkipLink_link__RWkQR">Accessibility help</a></li></ul><div class="Header_container__ptUfU"><a href="https://www.nice.org.uk/" aria-label="Home" class="Header_home__QrJHW" data-tracking="Logo"><svg viewBox="0 0 4411 512" fill="none" xmlns="http://www.w3.org/2000/svg" class="Header_icon__2lJSt" aria-hidden="true" focusable="false"><path d="M395.255 39.65v434.318h-79.301l-188.91-273.361h-3.237v273.361H32V39.65h80.625l187.439 273.214h3.826V39.65h91.365ZM550.032 39.65h-91.807v434.318h91.807V39.65ZM996.266 191.779h-92.837c-1.765-12.064-5.149-22.657-10.446-32.073-5.296-9.416-11.917-17.361-20.156-24.129-8.239-6.621-17.655-11.77-28.248-15.301-10.741-3.531-22.216-5.297-34.722-5.297-22.511 0-42.078 5.591-58.704 16.626-16.625 11.034-29.572 27.218-38.841 48.404-9.122 21.186-13.83 46.786-13.83 76.947s4.561 56.938 13.83 77.977 22.216 36.929 38.841 47.669c16.626 10.74 36.046 16.037 57.968 16.037 12.359 0 23.688-1.618 34.281-4.855s19.862-7.945 28.101-14.271c8.239-6.327 15.007-13.977 20.45-22.952 5.444-8.975 9.269-19.421 11.329-30.897l92.837.442c-2.354 19.862-8.386 39.135-17.95 57.526-9.563 18.391-22.363 34.869-38.4 49.435-16.036 14.418-35.163 25.894-57.232 34.28-22.069 8.386-47.08 12.653-75.034 12.653-38.694 0-73.269-8.828-103.724-26.336s-54.437-42.961-72.092-76.064c-17.655-33.251-26.483-73.416-26.483-120.644 0-47.227 8.975-87.687 26.777-120.938 17.802-33.25 41.931-58.556 72.533-76.064 30.603-17.508 64.883-26.189 102.989-26.189 25.158 0 48.552 3.532 70.032 10.594 21.628 7.062 40.754 17.36 57.379 30.896 16.626 13.536 30.308 30.014 40.754 49.582 10.593 19.568 17.214 41.784 20.304 66.942M1049.53 473.968V39.65h292.63v75.771h-200.83V218.85h185.82v75.771h-185.82v103.724h201.71v75.623h-293.51ZM1599.34 168.68h-1.62l-89.6-128.882h-19.13v163.751h19.87V74.961h1.47l89.3 128.588h19.13V39.798h-19.42V168.68ZM1726.31 127.779c-2.21 1.177-5.59 2.06-10.3 2.649-4.71.441-10.74 1.177-18.25 2.207-5.73.735-11.32 1.765-17.06 2.942-5.59 1.324-10.74 3.09-15.45 5.591-4.71 2.501-8.39 5.885-11.18 10.299-2.8 4.413-4.12 10.151-4.12 17.213 0 7.945 1.91 14.86 5.59 20.451 3.68 5.591 8.83 9.858 15.15 12.8 6.33 2.943 13.39 4.414 21.19 4.414 7.21 0 13.24-1.03 18.1-3.237 5-2.06 8.97-4.708 11.91-7.798 2.95-3.089 5.15-5.885 6.33-8.533h1.03v16.625h18.83V122.63c0-9.71-1.62-17.508-4.85-23.393-3.24-5.885-7.21-10.152-12.07-13.094-4.85-2.943-9.85-4.856-15-5.738-5.15-.883-9.71-1.472-13.69-1.472-6.18 0-12.5.883-18.83 2.501-6.33 1.619-12.21 4.561-17.51 8.828-5.29 4.12-9.71 10.005-12.8 17.508l17.95 6.327c2.06-4.414 5.74-8.681 10.74-12.653 5.15-3.973 12.21-5.885 21.19-5.885 8.97 0 15.15 2.207 19.42 6.62 4.27 4.414 6.47 10.446 6.47 18.391v.589c0 3.089-1.03 5.149-3.23 6.326l.44.294Zm3.23 31.338c0 5.15-1.32 10.005-3.97 14.566-2.65 4.708-6.47 8.386-11.62 11.329-5.15 2.942-11.48 4.413-18.98 4.413s-13.68-1.618-18.54-5.002c-4.85-3.384-7.35-8.239-7.35-14.86 0-4.855 1.32-8.533 3.82-11.328 2.65-2.796 6.03-4.856 10.3-6.327 4.27-1.471 8.83-2.501 13.68-3.09 2.06-.294 4.71-.588 7.95-1.029 3.23-.442 6.62-.883 10.15-1.472 3.53-.588 6.62-1.177 9.27-2.06 2.65-.735 4.41-1.618 5.29-2.648v17.508ZM1791.19 173.536c0 7.209 1.62 13.094 5 17.802 3.39 4.708 7.51 8.239 12.66 10.446 5.15 2.207 10.3 3.384 15.59 3.384 3.53 0 6.48-.294 8.68-.736 2.21-.441 4.12-1.03 5.3-1.471l-3.83-16.92c-.73.147-1.91.295-3.23.589-1.33.294-3.09.294-5.15.294-2.8 0-5.45-.441-7.8-1.324-2.5-.883-4.56-2.648-6.03-5.297-1.62-2.648-2.36-6.62-2.36-11.917v-71.65h26.19V80.699h-26.19V51.274h-18.83v29.425h-18.54v16.037h18.54v76.8ZM1883.59 80.699h-18.84v122.85h18.84V80.699ZM1874.32 34.648c-3.68 0-6.77 1.324-9.42 3.825-2.65 2.502-3.97 5.591-3.97 8.975 0 3.384 1.32 6.474 3.97 8.975 2.65 2.501 5.74 3.825 9.42 3.825 3.68 0 6.77-1.177 9.41-3.825 2.65-2.648 3.98-5.59 3.98-8.975 0-3.384-1.33-6.473-3.98-8.974-2.64-2.502-5.73-3.826-9.41-3.826ZM1997.17 87.025c-8.39-5.296-18.1-7.945-29.13-7.945-11.04 0-20.75 2.649-29.13 7.945-8.39 5.297-14.86 12.653-19.57 22.216-4.71 9.564-7.06 20.745-7.06 33.545s2.35 23.835 7.06 33.251c4.71 9.563 11.18 16.919 19.57 22.216 8.38 5.296 18.09 7.945 29.13 7.945 11.03 0 20.74-2.649 29.13-7.945 8.38-5.297 14.86-12.653 19.57-22.216 4.7-9.563 7.06-20.598 7.06-33.251 0-12.653-2.36-23.981-7.06-33.545-4.71-9.563-11.19-16.92-19.57-22.216Zm3.68 78.566c-2.65 7.062-6.62 12.653-12.07 17.066-5.44 4.267-12.36 6.474-20.74 6.474-8.39 0-15.3-2.207-20.75-6.474-5.44-4.266-9.41-10.004-12.06-17.066-2.65-7.062-3.97-14.713-3.97-22.805s1.32-15.889 3.97-22.952c2.65-7.062 6.62-12.8 12.06-17.213 5.45-4.414 12.36-6.621 20.75-6.621 8.38 0 15.3 2.207 20.74 6.621 5.45 4.413 9.42 10.151 12.07 17.213 2.64 7.063 3.97 14.713 3.97 22.952 0 8.239-1.33 15.89-3.97 22.805ZM2130.02 84.23c-6.18-3.384-13.53-5.002-21.77-5.002-9.27 0-16.77 1.912-22.66 5.738-5.88 3.825-10.3 8.827-13.09 15.154h-1.62V80.846h-18.24V203.55h18.83v-73.858c0-7.209 1.32-13.241 4.12-18.244 2.65-5.002 6.47-8.827 11.18-11.475 4.71-2.649 10-3.973 16.04-3.973 8.68 0 15.59 2.648 20.59 8.092 5.01 5.444 7.51 12.947 7.51 22.658v76.8h18.83v-77.977c0-10.446-1.77-19.127-5.15-25.895-3.53-6.915-8.24-11.917-14.57-15.3v-.148ZM2256.99 186.924h1.03v16.625h18.84V122.63c0-9.71-1.62-17.508-4.86-23.393-3.24-5.885-7.21-10.152-12.06-13.094-4.86-2.943-9.86-4.856-15.01-5.738-5.15-.883-9.71-1.472-13.68-1.472-6.18 0-12.51.883-18.83 2.501-6.33 1.619-12.22 4.561-17.51 8.828-5.3 4.12-9.71 10.005-12.8 17.508l17.95 6.327c2.06-4.414 5.73-8.681 10.74-12.653 5.15-3.973 12.21-5.885 21.18-5.885 8.98 0 15.16 2.207 19.42 6.62 4.27 4.414 6.48 10.446 6.48 18.391v.589c0 3.089-1.03 5.149-3.24 6.326-2.21 1.177-5.59 2.06-10.3 2.648-4.71.442-10.74 1.177-18.24 2.207-5.74.736-11.33 1.766-17.07 2.943-5.59 1.324-10.74 3.089-15.45 5.591-4.7 2.501-8.38 5.885-11.18 10.298-2.79 4.414-4.12 10.152-4.12 17.214 0 7.945 1.91 14.86 5.59 20.451 3.68 5.591 8.83 9.857 15.16 12.8 6.32 2.942 13.39 4.414 21.18 4.414 7.21 0 13.24-1.03 18.1-3.237 5-2.06 8.97-4.708 11.92-7.798 2.94-3.09 5.15-5.885 6.32-8.533l.44.441Zm-14.71-1.912c-5.15 2.942-11.47 4.413-18.98 4.413-7.5 0-13.68-1.618-18.54-5.002-4.85-3.384-7.35-8.239-7.35-14.86 0-4.855 1.32-8.533 3.82-11.328 2.65-2.796 6.04-4.856 10.3-6.327 4.27-1.471 8.83-2.501 13.69-3.09 2.06-.294 4.7-.588 7.94-1.029 3.24-.442 6.62-.883 10.15-1.472 3.53-.588 6.62-1.177 9.27-2.06 2.65-.735 4.41-1.618 5.3-2.648v17.214c0 5.149-1.33 10.005-3.97 14.566-2.65 4.708-6.48 8.386-11.63 11.328v.295ZM2330.11 39.798h-18.83v163.751h18.83V39.798ZM2450.46 39.798h-19.86v163.751h19.86V39.798ZM2506.37 129.692c0-7.209 1.33-13.241 4.12-18.244 2.65-5.002 6.47-8.827 11.18-11.476 4.71-2.648 10.01-3.972 16.04-3.972 8.68 0 15.59 2.648 20.6 8.092 5 5.444 7.5 12.947 7.5 22.657v76.8h18.83v-77.977c0-10.446-1.76-19.126-5.15-25.894-3.53-6.915-8.24-11.917-14.56-15.301-6.18-3.384-13.54-5.002-21.78-5.002-9.27 0-16.77 1.912-22.65 5.738-5.89 3.825-10.3 8.827-13.1 15.154h-1.62V80.993h-18.24V203.55h18.83v-73.857ZM2700.43 148.23c-5.44-5.444-13.53-9.563-24.57-12.212l-18.24-4.413c-7.21-1.766-12.66-4.12-16.04-6.768-3.38-2.648-5.15-6.474-5.15-11.182 0-5.296 2.5-9.71 7.51-13.094 5-3.384 11.18-5.15 18.68-5.15 5.44 0 10 .883 13.54 2.649 3.53 1.765 6.32 3.972 8.38 6.62 2.06 2.649 3.68 5.444 4.71 8.24l16.92-4.856c-2.94-8.68-7.8-15.742-14.86-21.186-6.92-5.296-16.48-7.945-28.69-7.945-8.68 0-16.33 1.472-23.1 4.561-6.77 3.09-12.21 7.21-16.04 12.506-3.82 5.297-5.88 11.476-5.88 18.391 0 8.533 2.65 15.595 7.94 21.186 5.3 5.591 13.54 9.71 24.72 12.359l20.45 4.855c6.18 1.471 10.74 3.678 13.68 6.473 2.95 2.943 4.42 6.474 4.42 10.741 0 5.296-2.65 9.857-7.8 13.535-5.15 3.678-12.21 5.591-21.04 5.591-7.8 0-13.98-1.618-18.68-5.002-4.71-3.384-7.95-8.239-9.71-14.86l-17.95 4.414c2.2 10.446 7.35 18.391 15.59 23.834 8.24 5.444 18.54 8.092 31.05 8.092 9.56 0 17.95-1.618 25.15-4.855 7.21-3.237 12.8-7.651 16.78-13.094 3.97-5.591 6.03-11.77 6.03-18.832 0-8.534-2.65-15.596-8.09-21.039l.29.441ZM2745.31 173.536c0 7.209 1.62 13.094 5 17.802s7.5 8.239 12.65 10.446c5.15 2.207 10.3 3.384 15.6 3.384 3.53 0 6.47-.294 8.68-.736 2.21-.441 4.12-1.03 5.3-1.471l-3.83-16.92c-.74.147-1.91.295-3.24.589-1.32.294-3.09.294-5.15.294-2.79 0-5.44-.441-7.79-1.324-2.51-.883-4.56-2.648-6.04-5.297-1.61-2.648-2.35-6.62-2.35-11.917v-71.65h26.19V80.699h-26.19V51.274h-18.83v29.425h-18.54v16.037h18.54v76.8ZM2828.43 34.648c-3.67 0-6.76 1.324-9.41 3.825-2.65 2.502-3.97 5.591-3.97 8.975 0 3.384 1.32 6.474 3.97 8.975 2.65 2.501 5.74 3.825 9.41 3.825 3.68 0 6.77-1.177 9.42-3.825 2.65-2.648 3.97-5.59 3.97-8.975 0-3.384-1.32-6.473-3.97-8.974-2.65-2.502-5.74-3.826-9.42-3.826ZM2837.7 80.699h-18.83v122.85h18.83V80.699ZM2880.66 173.536c0 7.209 1.62 13.094 5.01 17.802 3.38 4.708 7.5 8.239 12.65 10.446 5.15 2.207 10.3 3.384 15.59 3.384 3.54 0 6.48-.294 8.68-.736 2.21-.441 4.12-1.03 5.3-1.471l-3.82-16.92c-.74.147-1.92.295-3.24.589-1.33.294-3.09.294-5.15.294-2.8 0-5.44-.441-7.8-1.324-2.5-.883-4.56-2.648-6.03-5.297-1.62-2.648-2.35-6.62-2.35-11.917v-71.65h26.18V80.699h-26.18V51.274h-18.84v29.425h-18.53v16.037h18.53v76.8ZM3030.29 182.805h1.33v20.744h18.83V80.699h-18.83v72.68c0 7.651-1.62 13.977-5.01 18.98-3.38 5.002-7.5 8.68-12.36 11.034-4.85 2.354-9.71 3.678-14.41 3.678-7.8 0-14.28-2.648-19.28-7.945-5-5.296-7.5-12.505-7.5-21.48V80.699h-18.83v77.977c0 10.446 1.76 19.126 5.15 25.894 3.38 6.915 8.09 11.917 14.12 15.301 6.03 3.384 12.8 5.15 20.45 5.15 9.27 0 16.92-2.207 23.1-6.474 6.03-4.267 10.59-9.71 13.39-15.89l-.15.148ZM3093.26 173.536c0 7.209 1.62 13.094 5 17.802 3.39 4.708 7.51 8.239 12.66 10.446 5.15 2.207 10.29 3.384 15.59 3.384 3.53 0 6.47-.294 8.68-.736 2.21-.441 4.12-1.03 5.3-1.471l-3.83-16.92c-.73.147-1.91.295-3.23.589-1.33.294-3.09.294-5.15.294-2.8 0-5.45-.441-7.8-1.324-2.5-.883-4.56-2.648-6.03-5.297-1.62-2.648-2.36-6.62-2.36-11.917v-71.65h26.19V80.699h-26.19V51.274h-18.83v29.425h-18.54v16.037h18.54v76.8ZM3251.13 92.763c-5.15-4.708-10.74-8.239-17.07-10.299-6.33-2.06-12.5-3.236-18.98-3.236-11.03 0-20.74 2.648-28.98 8.092-8.24 5.443-14.71 12.947-19.42 22.51-4.71 9.563-6.92 20.745-6.92 33.251 0 12.505 2.36 23.54 6.92 33.103 4.56 9.563 11.18 16.772 19.71 22.069 8.54 5.297 18.69 7.798 30.6 7.798 8.24 0 15.75-1.324 22.51-3.826 6.63-2.648 12.22-6.179 16.78-10.887 4.56-4.708 7.79-10.152 9.71-16.331l-18.25-5.149c-1.61 4.266-3.82 7.797-6.76 10.74-2.95 2.942-6.48 5.002-10.45 6.326-3.97 1.472-8.53 2.06-13.54 2.06-7.65 0-14.27-1.618-20.01-5.002-5.73-3.384-10.29-8.239-13.53-14.566-2.94-5.738-4.27-12.947-4.56-21.039h89.01v-7.945c0-11.476-1.47-21.186-4.56-28.984-3.09-7.797-7.06-14.124-12.21-18.979v.294Zm-72.09 39.577c.29-5.738 1.61-11.034 4.12-16.184 2.94-5.885 7.06-10.74 12.65-14.418 5.44-3.678 11.92-5.59 19.42-5.59 6.77 0 12.8 1.618 17.8 4.707 5 3.09 8.98 7.504 11.62 12.947 2.8 5.444 4.12 11.623 4.12 18.538h-69.73ZM3414.73 96.736V80.699h-27.51V68.193c0-6.032 1.32-10.74 4.12-13.83s7.21-4.708 13.54-4.708c2.64 0 4.85.294 6.62.736 1.76.441 2.94.883 3.97 1.177l5.44-16.331c-1.47-.589-3.68-1.324-6.62-2.06S3407.52 32 3402.96 32c-5.88 0-11.47 1.177-16.77 3.531-5.3 2.354-9.56 5.885-12.95 10.593-3.23 4.708-5 10.593-5 17.655V80.7h-19.86v16.037h19.86v106.813h18.83V96.736h27.66ZM3534.79 176.037c4.7-9.563 7.06-20.598 7.06-33.251 0-12.653-2.36-23.981-7.06-33.545-4.71-9.563-11.19-16.92-19.57-22.216-8.39-5.296-18.1-7.945-29.13-7.945-11.04 0-20.75 2.649-29.13 7.945-8.39 5.297-14.86 12.653-19.57 22.216-4.71 9.564-7.06 20.745-7.06 33.545s2.35 23.835 7.06 33.251c4.71 9.563 11.18 16.919 19.57 22.216 8.38 5.296 18.09 7.945 29.13 7.945 11.03 0 20.74-2.649 29.13-7.945 8.38-5.297 14.86-12.653 19.57-22.216Zm-15.75-10.446c-2.65 7.062-6.62 12.653-12.06 17.066-5.44 4.267-12.36 6.474-20.75 6.474-8.38 0-15.3-2.207-20.74-6.474-5.44-4.266-9.42-10.004-12.07-17.066-2.64-7.062-3.97-14.713-3.97-22.805s1.33-15.889 3.97-22.952c2.65-7.062 6.63-12.8 12.07-17.213 5.44-4.414 12.36-6.621 20.74-6.621 8.39 0 15.31 2.207 20.75 6.621 5.44 4.413 9.41 10.151 12.06 17.213 2.65 7.063 3.98 14.713 3.98 22.952 0 8.239-1.33 15.89-3.98 22.805ZM3622.03 78.786c-7.35 0-13.98 1.913-19.86 5.738-5.89 3.825-9.86 8.68-12.21 14.86h-1.33V80.846h-18.24v122.703h18.83v-77.682c0-5.591 1.33-10.446 3.98-14.86 2.64-4.267 6.32-7.798 11.03-10.299 4.71-2.501 10-3.678 15.89-3.678 2.5 0 4.85.147 7.21.588 2.35.442 3.68.589 4.41.736V79.228c-1.03 0-2.65-.148-4.71-.295h-5.15l.15-.147ZM1596.1 382.896h-87.24v-72.827h-19.87v163.752h19.87v-73.269h87.24v73.269h19.86V310.069h-19.86v72.827ZM1738.67 362.887c-5.15-4.708-10.74-8.239-17.07-10.299-6.33-2.059-12.51-3.236-18.98-3.236-11.03 0-20.74 2.648-28.98 8.092-8.24 5.443-14.72 12.947-19.42 22.51-4.71 9.563-6.92 20.745-6.92 33.25 0 12.506 2.36 23.541 6.92 33.104 4.56 9.563 11.18 16.772 19.71 22.069 8.53 5.296 18.69 7.798 30.6 7.798 8.24 0 15.75-1.325 22.51-3.826 6.62-2.648 12.22-6.179 16.78-10.887 4.56-4.708 7.79-10.152 9.71-16.331l-18.25-5.15c-1.62 4.267-3.82 7.798-6.76 10.741-2.95 2.942-6.48 5.002-10.45 6.326-3.97 1.471-8.53 2.06-13.54 2.06-7.65 0-14.27-1.618-20.01-5.002-5.73-3.384-10.29-8.239-13.53-14.566-2.94-5.738-4.27-12.947-4.56-21.039h89.01v-7.945c0-11.476-1.47-21.186-4.56-28.984-3.09-7.797-7.06-14.124-12.21-18.979v.294Zm-72.09 39.577c.29-5.738 1.61-11.034 4.11-16.184 2.95-5.885 7.07-10.74 12.66-14.418 5.44-3.678 11.91-5.591 19.42-5.591 6.77 0 12.8 1.619 17.8 4.708 5 3.09 8.98 7.504 11.62 12.947 2.8 5.444 4.12 11.623 4.12 18.538h-69.73ZM1859.75 356.561c-4.85-2.943-9.86-4.855-15.01-5.738s-9.71-1.471-13.68-1.471c-6.18 0-12.5.882-18.83 2.501-6.33 1.618-12.21 4.561-17.51 8.827-5.3 4.12-9.71 10.005-12.8 17.508l17.95 6.327c2.06-4.414 5.74-8.681 10.74-12.653 5.15-3.972 12.21-5.885 21.19-5.885 8.97 0 15.15 2.207 19.42 6.621 4.26 4.413 6.47 10.446 6.47 18.39v.589c0 3.09-1.03 5.149-3.24 6.326-2.2 1.177-5.59 2.06-10.29 2.649-4.71.441-10.75 1.177-18.25 2.207-5.74.735-11.33 1.765-17.07 2.942-5.59 1.324-10.74 3.09-15.44 5.591-4.71 2.501-8.39 5.885-11.19 10.299-2.79 4.413-4.11 10.151-4.11 17.213 0 7.945 1.91 14.86 5.59 20.451 3.67 5.591 8.82 9.858 15.15 12.8 6.33 2.943 13.39 4.414 21.19 4.414 7.21 0 13.24-1.03 18.09-3.237 5.01-2.06 8.98-4.708 11.92-7.798 2.94-3.089 5.15-5.885 6.33-8.533h1.03v16.625h18.83v-80.919c0-9.711-1.62-17.508-4.86-23.393-3.23-5.885-7.21-10.152-12.06-13.095l.44.442Zm-2.06 72.827c0 5.15-1.32 10.005-3.97 14.566-2.65 4.708-6.48 8.386-11.62 11.329-5.15 2.942-11.48 4.413-18.98 4.413-7.51 0-13.69-1.618-18.54-5.002-4.86-3.384-7.36-8.239-7.36-14.86 0-4.855 1.33-8.533 3.83-11.328 2.65-2.796 6.03-4.856 10.3-6.327 4.26-1.471 8.82-2.501 13.68-3.089 2.06-.295 4.71-.589 7.94-1.03 3.24-.442 6.62-.883 10.16-1.472 3.53-.588 6.62-1.177 9.26-2.059 2.65-.736 4.42-1.619 5.3-2.649v17.508ZM1929.93 310.069h-18.83v163.752h18.83V310.069ZM2013.2 456.754c-1.32.294-3.09.294-5.15.294-2.79 0-5.44-.441-7.79-1.324-2.51-.883-4.56-2.648-6.04-5.296-1.61-2.649-2.35-6.621-2.35-11.918v-71.65h26.19v-16.037h-26.19v-29.425h-18.83v29.425h-18.54v16.037h18.54v76.8c0 7.209 1.62 13.094 5 17.802s7.5 8.239 12.65 10.446c5.15 2.207 10.3 3.384 15.6 3.384 3.53 0 6.47-.294 8.68-.736 2.21-.441 4.12-1.03 5.3-1.471l-3.83-16.92c-.74.148-1.91.295-3.24.589ZM2127.67 354.354c-6.33-3.384-13.68-5.002-21.92-5.002-9.71 0-17.36 1.912-23.1 5.591-5.74 3.825-10.15 8.827-12.95 15.154h-1.62v-60.175h-18.83v163.752h18.83v-73.858c0-7.209 1.48-13.241 4.27-18.244 2.8-5.002 6.62-8.827 11.48-11.475 4.85-2.649 10.44-3.973 16.62-3.973 8.83 0 15.89 2.648 20.89 8.092 5.01 5.444 7.51 12.947 7.51 22.658v76.8h18.83v-77.977c0-10.594-1.77-19.274-5.3-26.042-3.53-6.768-8.38-11.917-14.71-15.301ZM2320.99 356.561c-4.85-2.943-9.85-4.855-15-5.738s-9.71-1.471-13.69-1.471c-6.18 0-12.5.882-18.83 2.501-6.32 1.618-12.21 4.561-17.51 8.827-5.29 4.12-9.71 10.005-12.8 17.508l17.95 6.327c2.06-4.414 5.74-8.681 10.74-12.653 5.15-3.972 12.21-5.885 21.19-5.885 8.97 0 15.15 2.207 19.42 6.621 4.27 4.413 6.47 10.446 6.47 18.39v.589c0 3.09-1.03 5.149-3.23 6.326-2.21 1.177-5.59 2.06-10.3 2.649-4.71.441-10.74 1.177-18.25 2.207-5.73.735-11.32 1.765-17.06 2.942-5.59 1.324-10.74 3.09-15.45 5.591-4.71 2.501-8.39 5.885-11.18 10.299-2.8 4.413-4.12 10.151-4.12 17.213 0 7.945 1.91 14.86 5.59 20.451 3.68 5.591 8.83 9.858 15.15 12.8 6.33 2.943 13.39 4.414 21.19 4.414 7.21 0 13.24-1.03 18.1-3.237 5-2.06 8.97-4.708 11.91-7.798 2.95-3.089 5.15-5.885 6.33-8.533h1.03v16.625h18.83v-80.919c0-9.711-1.62-17.508-4.85-23.393-3.24-5.885-7.21-10.152-12.07-13.095l.44.442Zm-2.06 72.827c0 5.15-1.32 10.005-3.97 14.566-2.65 4.708-6.47 8.386-11.62 11.329-5.15 2.942-11.48 4.413-18.98 4.413s-13.68-1.618-18.54-5.002c-4.85-3.384-7.36-8.239-7.36-14.86 0-4.855 1.33-8.533 3.83-11.328 2.65-2.796 6.03-4.856 10.3-6.327 4.27-1.471 8.83-2.501 13.68-3.089 2.06-.295 4.71-.589 7.95-1.03 3.23-.442 6.62-.883 10.15-1.472 3.53-.588 6.62-1.177 9.27-2.059 2.65-.736 4.41-1.619 5.29-2.649v17.508ZM2449.88 354.501c-6.18-3.384-13.54-5.002-21.78-5.002-9.27 0-16.77 1.912-22.66 5.738-5.88 3.825-10.29 8.827-13.09 15.154h-1.62v-19.274h-18.24v122.851h18.83V400.11c0-7.209 1.32-13.241 4.12-18.243 2.65-5.003 6.47-8.828 11.18-11.476 4.71-2.648 10.01-3.973 16.04-3.973 8.68 0 15.59 2.649 20.6 8.092 5 5.444 7.5 12.948 7.5 22.658v76.8h18.83v-77.977c0-10.446-1.76-19.127-5.15-25.894-3.53-6.915-8.24-11.918-14.56-15.302v-.294ZM2588.03 370.538h-1.62c-1.32-2.06-3.38-4.855-5.74-8.239-2.5-3.384-6.03-6.327-10.74-8.975-4.7-2.648-11.03-3.972-18.98-3.972-10.29 0-19.42 2.648-27.36 7.797-7.95 5.15-13.98 12.506-18.54 21.922-4.56 9.416-6.62 20.745-6.62 33.545s2.21 24.276 6.62 33.839c4.41 9.563 10.59 16.92 18.39 22.069 7.8 5.149 16.92 7.798 27.07 7.798 7.95 0 14.27-1.324 18.98-3.973 4.71-2.648 8.39-5.59 10.89-8.974 2.5-3.384 4.56-6.18 5.88-8.387h2.21v18.833h18.24V310.069h-18.83v60.469h.15Zm-3.83 66.354c-2.64 7.062-6.62 12.506-11.91 16.478-5.3 3.972-11.63 5.885-19.28 5.885s-14.41-2.06-19.71-6.326c-5.3-4.12-9.27-9.858-11.92-16.92-2.65-7.062-3.97-15.007-3.97-23.834 0-8.828 1.32-16.479 3.97-23.393 2.65-6.915 6.62-12.506 11.92-16.479 5.3-4.119 11.92-6.179 20.01-6.179 8.09 0 14.12 1.913 19.42 5.738 5.3 3.825 9.12 9.269 11.77 16.184 2.65 6.915 3.97 15.007 3.97 24.129 0 9.121-1.32 17.508-4.12 24.57l-.15.147ZM2748.84 333.904c7.94-5.003 17.06-7.504 26.92-7.504 5.45 0 10.6.736 15.6 2.207 5 1.471 9.56 3.678 13.68 6.621 4.12 2.942 7.65 6.62 10.59 10.887 2.95 4.267 5.01 9.269 6.18 15.007h19.86c-1.47-8.386-4.26-15.89-8.09-22.51-3.97-6.621-8.82-12.212-14.71-16.773-5.88-4.561-12.51-8.092-19.71-10.593-7.21-2.354-15.01-3.531-23.25-3.531-13.98 0-26.34 3.384-37.22 10.299-10.89 6.768-19.42 16.478-25.6 29.131-6.18 12.653-9.42 27.513-9.42 44.726 0 17.214 3.09 32.221 9.42 44.727 6.32 12.506 14.86 22.216 25.6 29.131 10.88 6.768 23.24 10.299 37.22 10.299 8.24 0 16.04-1.177 23.25-3.531a65.066 65.066 0 0 0 19.71-10.446c5.89-4.561 10.74-10.152 14.71-16.773 3.98-6.62 6.62-14.124 8.09-22.51h-19.86c-1.17 5.591-3.23 10.593-6.18 15.007-2.94 4.414-6.47 7.945-10.59 10.887-4.12 2.943-8.68 5.15-13.68 6.621s-10.3 2.207-15.6 2.207c-9.86 0-18.83-2.501-26.92-7.504-8.09-5.002-14.42-12.358-19.13-22.216-4.71-9.857-7.06-21.774-7.06-35.899 0-14.124 2.35-26.188 7.06-35.898 4.71-9.711 11.04-17.067 19.13-22.217v.148ZM2946.58 356.561c-4.86-2.943-9.86-4.855-15.01-5.738s-9.71-1.471-13.68-1.471c-6.18 0-12.51.882-18.84 2.501-6.32 1.618-12.21 4.561-17.5 8.827-5.3 4.12-9.71 10.005-12.8 17.508l17.94 6.327c2.06-4.414 5.74-8.681 10.74-12.653 5.15-3.972 12.22-5.885 21.19-5.885 8.98 0 15.16 2.207 19.42 6.621 4.27 4.413 6.48 10.446 6.48 18.39v.589c0 3.09-1.03 5.149-3.24 6.326-2.21 1.177-5.59 2.06-10.3 2.649-4.71.441-10.74 1.177-18.24 2.207-5.74.735-11.33 1.765-17.07 2.942-5.59 1.324-10.74 3.09-15.45 5.591-4.71 2.501-8.39 5.885-11.18 10.299-2.8 4.413-4.12 10.151-4.12 17.213 0 7.945 1.91 14.86 5.59 20.451 3.68 5.591 8.83 9.858 15.16 12.8 6.32 2.943 13.38 4.414 21.18 4.414 7.21 0 13.24-1.03 18.1-3.237 5-2.06 8.97-4.708 11.91-7.798 2.95-3.089 5.15-5.885 6.33-8.533h1.03v16.625h18.83v-80.919c0-9.711-1.61-17.508-4.85-23.393-3.24-5.885-7.21-10.152-12.07-13.095l.45.442Zm-2.06 72.827c0 5.15-1.33 10.005-3.98 14.566-2.65 4.708-6.47 8.386-11.62 11.329-5.15 2.942-11.48 4.413-18.98 4.413s-13.68-1.618-18.54-5.002c-4.85-3.384-7.35-8.239-7.35-14.86 0-4.855 1.32-8.533 3.82-11.328 2.65-2.796 6.03-4.856 10.3-6.327 4.27-1.471 8.83-2.501 13.68-3.089 2.06-.295 4.71-.589 7.95-1.03 3.23-.442 6.62-.883 10.15-1.472 3.53-.588 6.62-1.177 9.27-2.059 2.65-.736 4.41-1.619 5.3-2.649v17.508ZM3049.56 349.057c-7.35 0-13.97 1.913-19.86 5.738-5.88 3.826-9.86 8.681-12.21 14.86h-1.32v-18.538h-18.25v122.851h18.84v-77.683c0-5.591 1.32-10.446 3.97-14.86 2.65-4.266 6.32-7.797 11.03-10.299 4.71-2.501 10.01-3.678 15.89-3.678 2.5 0 4.86.147 7.21.589 2.36.441 3.68.588 4.41.735v-19.126c-1.03 0-2.64-.147-4.7-.294h-5.15l.14-.295ZM3163.59 362.887c-5.15-4.708-10.74-8.239-17.07-10.299-6.32-2.059-12.5-3.236-18.98-3.236-11.03 0-20.74 2.648-28.98 8.092-8.24 5.443-14.71 12.947-19.42 22.51-4.71 9.563-6.92 20.745-6.92 33.25 0 12.506 2.36 23.541 6.92 33.104 4.56 9.563 11.18 16.772 19.71 22.069 8.54 5.296 18.69 7.798 30.6 7.798 8.24 0 15.75-1.325 22.52-3.826 6.62-2.648 12.21-6.179 16.77-10.887 4.56-4.708 7.8-10.152 9.71-16.331l-18.25-5.15c-1.61 4.267-3.82 7.798-6.76 10.741-2.95 2.942-6.48 5.002-10.45 6.326-3.97 1.471-8.53 2.06-13.54 2.06-7.65 0-14.27-1.618-20-5.002-5.74-3.384-10.3-8.239-13.54-14.566-2.94-5.738-4.27-12.947-4.56-21.039h89.01v-7.945c0-11.476-1.47-21.186-4.56-28.984-3.09-7.797-7.06-14.124-12.21-18.979v.294Zm-72.09 39.577c.29-5.738 1.61-11.034 4.12-16.184 2.94-5.885 7.06-10.74 12.65-14.418 5.44-3.678 11.92-5.591 19.42-5.591 6.77 0 12.8 1.619 17.8 4.708 5 3.09 8.98 7.504 11.62 12.947 2.8 5.444 4.12 11.623 4.12 18.538h-69.73ZM3294.82 400.552h73.86v-17.656h-73.86v-55.319h79.01v-17.508h-98.87v163.752h100.19v-17.656h-80.33v-55.613ZM3480.06 350.97l-29.43 50.17-29.42-50.17h-21.78l38.99 61.352-38.99 61.499h21.78l29.42-47.669 29.43 47.669h21.77l-39.72-61.499 39.72-61.352h-21.77ZM3554.06 372.009c5.45-3.825 11.92-5.738 19.28-5.738 8.38 0 15 2.207 19.86 6.474 5 4.414 8.09 9.269 9.56 14.86h18.83c-1.03-7.651-3.82-14.419-8.24-20.157-4.41-5.738-10.15-10.299-17.06-13.388-6.92-3.237-14.72-4.855-23.4-4.855-11.03 0-20.74 2.648-28.98 8.092-8.24 5.443-14.71 12.947-19.42 22.51-4.56 9.563-6.92 20.598-6.92 33.103 0 12.506 2.21 23.099 6.77 32.662 4.42 9.564 10.89 17.067 19.13 22.511 8.24 5.443 18.24 8.092 29.72 8.092 9.12 0 17.06-1.766 23.83-5.15 6.92-3.384 12.36-7.945 16.48-13.683 4.12-5.737 6.77-12.358 7.95-19.567h-18.84c-1.17 4.413-3.09 8.239-5.88 11.476-2.8 3.236-6.18 5.59-10.15 7.356-3.98 1.765-8.39 2.501-13.39 2.501-7.51 0-13.98-1.913-19.42-5.885-5.59-3.825-9.71-9.416-12.8-16.331-2.94-7.062-4.56-15.301-4.56-24.864 0-9.564 1.47-17.361 4.56-24.276 3.09-6.915 7.35-12.212 12.94-16.037l.15.294ZM3734.88 362.887c-5.15-4.708-10.74-8.239-17.07-10.299-6.33-2.059-12.5-3.236-18.98-3.236-11.03 0-20.74 2.648-28.98 8.092-8.24 5.443-14.71 12.947-19.42 22.51-4.71 9.563-6.92 20.745-6.92 33.25 0 12.506 2.36 23.541 6.92 33.104 4.56 9.563 11.18 16.772 19.71 22.069 8.54 5.296 18.69 7.798 30.6 7.798 8.24 0 15.75-1.325 22.51-3.826 6.63-2.648 12.22-6.179 16.78-10.887 4.56-4.708 7.79-10.152 9.71-16.331l-18.25-5.15c-1.61 4.267-3.82 7.798-6.76 10.741-2.95 2.942-6.48 5.002-10.45 6.326-3.97 1.471-8.53 2.06-13.54 2.06-7.65 0-14.27-1.618-20-5.002-5.74-3.384-10.3-8.239-13.54-14.566-2.94-5.738-4.27-12.947-4.56-21.039h89.01v-7.945c0-11.476-1.47-21.186-4.56-28.984-3.09-7.797-7.06-14.124-12.21-18.979v.294Zm-72.09 39.577c.29-5.738 1.61-11.034 4.12-16.184 2.94-5.885 7.06-10.74 12.65-14.418 5.44-3.678 11.92-5.591 19.42-5.591 6.77 0 12.8 1.619 17.8 4.708 5 3.09 8.98 7.504 11.62 12.947 2.8 5.444 4.12 11.623 4.12 18.538h-69.73ZM3799.17 310.069h-18.83v163.752h18.83V310.069ZM3852.58 310.069h-18.83v163.752h18.83V310.069ZM3972.78 362.887c-5.15-4.708-10.74-8.239-17.06-10.299-6.33-2.059-12.51-3.236-18.98-3.236-11.04 0-20.75 2.648-28.99 8.092-8.24 5.443-14.71 12.947-19.42 22.51-4.71 9.563-6.91 20.745-6.91 33.25 0 12.506 2.35 23.541 6.91 33.104 4.56 9.563 11.18 16.772 19.72 22.069 8.53 5.296 18.68 7.798 30.6 7.798 8.24 0 15.74-1.325 22.51-3.826 6.62-2.648 12.21-6.179 16.77-10.887 4.56-4.708 7.8-10.152 9.71-16.331l-18.24-5.15c-1.62 4.267-3.83 7.798-6.77 10.741-2.94 2.942-6.47 5.002-10.44 6.326-3.98 1.471-8.54 2.06-13.54 2.06-7.65 0-14.27-1.618-20.01-5.002-5.74-3.384-10.3-8.239-13.54-14.566-2.94-5.738-4.26-12.947-4.56-21.039h89.02v-7.945c0-11.476-1.48-21.186-4.57-28.984-3.09-7.797-7.06-14.124-12.21-18.979v.294Zm-72.09 39.577c.3-5.738 1.62-11.034 4.12-16.184 2.94-5.885 7.06-10.74 12.65-14.418 5.45-3.678 11.92-5.591 19.42-5.591 6.77 0 12.8 1.619 17.81 4.708 5 3.09 8.97 7.504 11.62 12.947 2.79 5.444 4.12 11.623 4.12 18.538h-69.74ZM4095.78 354.501c-6.18-3.384-13.54-5.002-21.78-5.002-9.27 0-16.77 1.912-22.65 5.738-5.89 3.825-10.3 8.827-13.1 15.154h-1.62v-19.274h-18.24v122.851h18.83V400.11c0-7.209 1.33-13.241 4.12-18.243 2.65-5.003 6.47-8.828 11.18-11.476 4.71-2.648 10.01-3.973 16.04-3.973 8.68 0 15.6 2.649 20.6 8.092 5 5.444 7.5 12.948 7.5 22.658v76.8h18.83v-77.977c0-10.446-1.76-19.127-5.15-25.894-3.53-6.915-8.24-11.918-14.56-15.302v-.294ZM4180.67 372.009c5.45-3.825 11.92-5.738 19.27-5.738 8.39 0 15.01 2.207 19.87 6.474 5 4.414 8.09 9.269 9.56 14.86h18.83c-1.03-7.651-3.82-14.419-8.24-20.157-4.41-5.738-10.15-10.299-17.06-13.388-6.92-3.237-14.72-4.855-23.4-4.855-11.03 0-20.74 2.648-28.98 8.092-8.24 5.443-14.71 12.947-19.42 22.51-4.56 9.563-6.92 20.598-6.92 33.103 0 12.506 2.21 23.099 6.77 32.662 4.41 9.564 10.89 17.067 19.13 22.511 8.24 5.443 18.24 8.092 29.72 8.092 9.12 0 17.06-1.766 23.83-5.15 6.92-3.384 12.36-7.945 16.48-13.683 4.12-5.737 6.77-12.358 7.95-19.567h-18.84c-1.17 4.413-3.09 8.239-5.88 11.476-2.8 3.236-6.18 5.59-10.15 7.356-3.98 1.765-8.39 2.501-13.39 2.501-7.51 0-13.98-1.913-19.42-5.885-5.59-3.825-9.71-9.416-12.8-16.331-2.95-7.062-4.56-15.301-4.56-24.864 0-9.564 1.47-17.361 4.56-24.276 3.09-6.915 7.35-12.212 12.94-16.037l.15.294ZM4378.12 410.85c0-11.475-1.48-21.186-4.57-28.983-3.08-7.798-7.06-14.125-12.21-18.98-5.15-4.708-10.74-8.239-17.06-10.299-6.33-2.059-12.51-3.236-18.98-3.236-11.04 0-20.75 2.648-28.99 8.092-8.24 5.443-14.71 12.947-19.42 22.51-4.71 9.563-6.91 20.745-6.91 33.25 0 12.506 2.35 23.541 6.91 33.104 4.56 9.563 11.18 16.772 19.72 22.069 8.53 5.296 18.68 7.798 30.6 7.798 8.24 0 15.74-1.325 22.51-3.826 6.62-2.648 12.21-6.179 16.77-10.887 4.56-4.708 7.8-10.152 9.71-16.331l-18.24-5.15c-1.62 4.267-3.83 7.798-6.77 10.741-2.94 2.942-6.47 5.002-10.44 6.326-3.98 1.471-8.54 2.06-13.54 2.06-7.65 0-14.27-1.618-20.01-5.002-5.74-3.384-10.3-8.239-13.53-14.566-2.95-5.738-4.27-12.947-4.57-21.039h89.02v-7.945.294Zm-88.87-8.386c.3-5.738 1.62-11.034 4.12-16.184 2.94-5.885 7.06-10.74 12.65-14.418 5.45-3.678 11.92-5.591 19.42-5.591 6.77 0 12.8 1.619 17.81 4.708 5 3.09 8.97 7.504 11.62 12.947 2.8 5.444 4.12 11.623 4.12 18.538h-69.74Z" fill="currentColor"></path></svg></a><div class="Header_wrapper__8WbBA"><div class="Header_search__NacHH"><form id="global-nav-search-form" role="search" action="/search" class="Search_search__do5Gn"><label class="Search_label___vtvh" for="autocomplete">Search NICE…</label><div class="Autocomplete_ac__CP9eu"><div class="autocomplete__wrapper"><input type="search" id="autocomplete" name="q" class="autocomplete__input autocomplete__input--default" placeholder="Search NICE…" data-hj-allow="" maxLength="512" value=""/></div></div><button class="Search_button__54cGs" type="submit" aria-label="Perform search"><svg width="1em" height="1em" viewBox="0 0 512 512" fill="none" xmlns="http://www.w3.org/2000/svg" class="Search_icon___aEsS" aria-hidden="true" focusable="false"><path d="M83.784 476.472 197.112 363.16c30.144 20.32 65.056 30.528 100.032 30.528 45.904 0 91.776-17.488 126.8-52.528 70.064-70.064 70.064-183.584 0-253.616C388.936 52.504 343.048 35 297.144 35c-45.904 0-91.808 17.504-126.848 52.528-61.696 61.696-68.976 157.12-21.968 226.864L35 427.752l48.784 48.72Zm213.36-137.952c-33.168 0-64.352-12.896-87.792-36.368-48.416-48.448-48.416-127.2 0-175.616 23.44-23.44 54.64-36.352 87.792-36.352s64.336 12.912 87.776 36.368c23.44 23.456 36.384 54.64 36.384 87.792s-12.928 64.352-36.384 87.792c-23.456 23.472-54.624 36.368-87.776 36.368v.016Z" fill="currentColor"></path></svg></button><a href="#content-start" class="SkipLink_link__RWkQR">Skip to content</a></form></div><button class="Header_mobileMenuBtn__pbI_i" id="header-menu-button" type="button" aria-controls="header-menu" aria-expanded="false" aria-haspopup="menu" aria-label="Expand site menu">Menu</button><div class="Header_account___MDc2"><a data-tracking="Sign in" href="https://accounts.nice.org.uk/signin" class="Account_button__YKHtB">Sign in</a></div></div></div><div id="header-menu" class="Nav_wrapper__E2OlM"><nav class="Nav_nav__PR6Nm" aria-label="primary navigation" data-tracking="Primary navigation"><div class="Nav_menuWrapper__mGyWw"><ul class="NavLinks_menuList__Z3HaN" aria-labelledby="header-menu-button"><li data-tracking="Guidance"><a href="https://www.nice.org.uk/guidance" class="NavLinks_link___hLDV" id="navlink-guidance"><span>Guidance</span></a></li><li data-tracking="Standards and indicators"><a href="https://www.nice.org.uk/standards-and-indicators" class="NavLinks_link___hLDV" id="navlink-standards-and-indicators"><span>Standards and indicators</span></a></li><li data-tracking="Life sciences"><a href="https://www.nice.org.uk/about/what-we-do/life-sciences" class="NavLinks_link___hLDV" id="navlink-life-sciences"><span>Life sciences</span></a></li><li data-tracking="British National Formulary (BNF)"><a href="https://bnf.nice.org.uk/" class="NavLinks_link___hLDV" id="navlink-bnf" aria-label="false"><span>British National Formulary (BNF)</span></a></li><li data-tracking="British National Formulary for Children (BNFC)"><a href="https://bnfc.nice.org.uk/" class="NavLinks_link___hLDV" id="navlink-bnfc" aria-label="false"><span>British National Formulary for Children (BNFC)</span></a></li><li data-tracking="Clinical Knowledge Summaries (CKS)"><a href="https://cks.nice.org.uk/" class="NavLinks_link___hLDV" id="navlink-cks" aria-label="false"><span>Clinical Knowledge Summaries (CKS)</span></a></li><li data-tracking="About"><a href="https://www.nice.org.uk/about" class="NavLinks_link___hLDV" id="navlink-about"><span>About</span></a></li></ul></div></nav></div></header></div></div><main class="Main_main__quUAo Main_withPadding__DVea8"><div class="container" data-component="container"><article class="StoryblokNewsArticle_newsSectionArticle__q3t9A"><div class="grid"><div data-g="12" data-component="grid-item"><div class="page-header page-header--full-width-light page-header--vertical-padding-loose" data-component="page-header"><div class="page-header__full-width-container"><div class="page-header__breadcrumbs"><nav aria-label="Breadcrumbs" role="navigation" data-component="breadcrumbs" class=""><ol class="breadcrumbs"><li class="breadcrumbs__crumb"><a href="/">Home</a></li><li class="breadcrumbs__crumb"><a href="/news">News</a></li><li class="breadcrumbs__crumb"><a href="/news/articles">News articles</a></li></ol></nav><script type="application/ld+json">{"@context":"http://schema.org","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"/","name":"Home"}},{"@type":"ListItem","position":2,"item":{"@id":"/news","name":"News"}},{"@type":"ListItem","position":3,"item":{"@id":"/news/articles","name":"News articles"}}]}</script></div><h1 class="page-header__heading ">New study shows NICE Advice support can reduce appraisal timelines by 3 months</h1><p class="page-header__lead">Companies who receive scientific advice from our NICE Advice service may experience a faster path to guidance publication, a study has found. </p><div class="page-header__description"><div class="NewsPageHeaderFooter_footer__spxP_"><span class="tag tag--outline" data-component="tag" data-testid="pageTag">News</span><time dateTime="2024-11-14 00:00">14 November 2024</time></div></div></div></div></div><div data-g="12 md:7" data-component="grid-item"><picture><source srcSet="https://a.storyblok.com/f/243782/2495x1201/766442ac9a/perscription-being-delivered-to-a-patient-at-home.jpg/m/760x0/filters:format%28avif%29:quality%2880%29" type="image/avif"/><source srcSet="https://a.storyblok.com/f/243782/2495x1201/766442ac9a/perscription-being-delivered-to-a-patient-at-home.jpg/m/760x0/filters:format%28webp%29:quality%2880%29" type="image/webp"/><img class="StoryblokNewsArticle_featuredImage__ZTTnJ" height="428px" loading="eager" width="760px" role="presentation" src="https://a.storyblok.com/f/243782/2495x1201/766442ac9a/perscription-being-delivered-to-a-patient-at-home.jpg/m/760x0/filters:format%28jpeg%29:quality%2880%29" alt=""/></picture><div class="StoryblokRichText_storyblokRichTextWrapper__jAYnD " data-testid="storyblok-rich-text"><p><a href="https://www.ispor.org/conferences-education/conferences/upcoming-conferences/ispor-europe-2024/program/program/paper/euro2024-4008/19100/the-value-of-nice-scientific-advice"><span>The research</span></a><span>, which will be presented to delegates at the ISPOR conference in Barcelona, Spain, examined NICE technology appraisal and highly specialised technologies guidance published between June 2020 and May 2023. It found that products benefiting from NICE Advice’s scientific advice service had a shorter time from marketing authorisation to the publication of NICE guidance.</span><br/><br/><span>According to the study, technologies that received scientific advice took a median of 312 days to progress from marketing authorisation to NICE guidance publication. In contrast, those without such advice required a median of 400 days – a difference of nearly 3 months.</span><br/><br/><span>The analysis included 230 technology appraisal and highly specialised technologies guidance documents, of which 51 technologies had received scientific advice from NICE Advice. While the study acknowledges that various factors can influence the time to guidance publication, the majority of these would be expected to apply to technologies with or without scientific advice.</span></p><figure class="Blockquote_quote__Skftl"><blockquote><p>This study reinforces the value of engaging with NICE Advice’s scientific advice service early in the product development process. Our depth of knowledge and unique insights can help companies effectively prepare for their NICE evaluation, potentially streamlining their path through the process, and helping to get innovative technologies to patients faster.</p></blockquote><figcaption class="blockquote-footer">Andrew Walsh, associate director of NICE Advice</figcaption></figure><p>The results support <a href="https://www.valueinhealthjournal.com/article/S1098-3015(20)33008-4/fulltext">previous findings</a> on the benefits of NICE Advice’s scientific advice service. This earlier study showed that between 2009 and 2019, the median time from marketing authorisation to publication of NICE guidance was 296 days for products that used NICE Advice’s scientific advice service compared to 405 days for products that did not.<br/><br/>As the life sciences sector continues to innovate, our independent and highly confidential support service, <a href="https://www.nice.org.uk/about/what-we-do/life-sciences/nice-advice-service">NICE Advice</a>, offers a valuable resource to companies aiming to speed up the NICE appraisal process and get their new treatments to NHS patients faster. By partnering with NICE Advice, companies can ensure their technologies meet NHS needs from the early stages of development, guiding them in collecting high-quality evidence that resonates with decision-makers.</p></div></div><aside data-g="12 md:4 md:push:1" data-component="grid-item" class="StoryblokNewsArticle_articleSidebar__GEqbn"><div class="panel panel--primary" data-component="panel--primary"><h2 class="h5">Associated guidance and resources</h2><a href="https://www.nice.org.uk/about/what-we-do/life-sciences/nice-advice-service">NICE Advice</a><hr/><a href="https://www.ispor.org/conferences-education/conferences/upcoming-conferences/ispor-europe-2024/program/program/paper/euro2024-4008/19100/the-value-of-nice-scientific-advice">The value of NICE scientific advice</a></div></aside><div data-g="12" data-component="grid-item"><section class="action-banner" data-component="action-banner"><div class="action-banner__container"><div class="action-banner__inner"><div class="action-banner__text"><h2 class="action-banner__title">Sign up for our newsletters and alerts</h2><div class="action-banner__intro">Keeping you up to date with important developments at NICE.</div></div><div class="action-banner__actions"><a class="btn btn--cta NewsLetterSignUp_signupCta__9jRTZ" href="/nice-newsletters-and-alerts" data-component="button--cta">Sign up for newsletters and alerts</a></div></div></div></section></div></div></article></div><div class="BackToTop_wrapper__lWIkB"><nav aria-labelledby="back-to-top-link" class="BackToTop_nav__PkXNm"><a class="BackToTop_anchor__D_DFc" id="back-to-top-link" href="#top"><div class="container BackToTop_container__eSpc_" data-component="container"><svg width="1em" height="1em" viewBox="0 0 512 512" fill="none" xmlns="http://www.w3.org/2000/svg" class="icon" aria-hidden="true" focusable="false"><path d="M478.152 338.576c0 10.091-3.525 18.661-10.576 25.712l-21.424 21.424c-7.243 7.243-15.909 10.864-26 10.864-10.283 0-18.853-3.621-25.712-10.864L255.576 247.136 116.712 385.712c-6.859 7.243-15.429 10.864-25.712 10.864s-18.853-3.621-25.712-10.864l-21.424-21.424C36.621 357.429 33 348.859 33 338.576c0-10.091 3.621-18.757 10.864-26l186-186c7.051-7.051 15.621-10.576 25.712-10.576 9.909 0 18.576 3.525 26 10.576l185.712 186c7.243 7.243 10.864 15.909 10.864 26Z" fill="currentColor"></path></svg> Back to top</div></a></nav></div></main><noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-M55QTQ" height="0" width="0" style="display:none"></iframe></noscript><footer class="Footer_footer___AIsg" data-tracking="Global footer"><div class="Footer_container__r0Ib_"><a href="https://www.nice.org.uk/" class="Footer_logo__pKuR2" aria-label="Go to NICE home page"><svg width="1em" height="1em" viewBox="0 0 1381 512" fill="none" xmlns="http://www.w3.org/2000/svg" class="icon" aria-hidden="true" focusable="false"><path d="M396.692 37.908v436.036h-79.615L127.42 199.501h-3.25v274.443H32V37.908h80.944l188.181 274.295h3.84V37.908h91.727ZM552.082 37.908h-92.17v436.036h92.17V37.908ZM1000.08 190.639h-93.202c-1.773-12.112-5.17-22.747-10.488-32.2-5.317-9.454-11.964-17.43-20.236-24.225-8.271-6.647-17.725-11.816-28.36-15.361-10.782-3.545-22.304-5.318-34.859-5.318-22.599 0-42.245 5.613-58.936 16.691-16.691 11.078-29.689 27.326-38.995 48.596-9.158 21.27-13.884 46.972-13.884 77.252 0 30.28 4.579 57.163 13.884 78.285 9.306 21.123 22.304 37.075 38.995 47.858 16.691 10.783 36.189 16.1 58.198 16.1 12.407 0 23.781-1.625 34.416-4.874 10.635-3.25 19.94-7.976 28.212-14.328 8.272-6.351 15.066-14.032 20.531-23.042 5.466-9.011 9.306-19.498 11.374-31.019l93.204.443c-2.363 19.941-8.419 39.29-18.02 57.754-9.601 18.463-22.452 35.007-38.552 49.63-16.101 14.475-35.303 25.997-57.459 34.416C863.747 475.716 838.636 480 810.572 480c-38.848 0-73.559-8.863-104.135-26.44-30.575-17.577-54.652-43.131-72.377-76.365-17.725-33.382-26.588-73.707-26.588-121.121 0-47.415 9.011-88.034 26.883-121.417 17.873-33.382 42.097-58.788 72.821-76.365C737.899 40.715 772.315 32 810.572 32c25.258 0 48.744 3.545 70.309 10.635 21.713 7.09 40.915 17.43 57.606 31.019 16.691 13.589 30.428 30.132 40.916 49.778 10.635 19.645 17.281 41.949 20.383 67.207M1053.55 473.944V37.908h293.79v76.07h-201.62v103.839h186.56v76.07h-186.56v104.135h202.51v75.922h-294.68Z" fill="currentColor"></path></svg></a><nav class="Services_wrapper__xryL4" aria-label="Our services"><ul class="Services_list__GzZL_"><li><a href="https://www.nice.org.uk/guidance" class="Services_link__jcE9g">Guidance</a></li><li><a href="https://www.nice.org.uk/standards-and-indicators" class="Services_link__jcE9g">Standards and indicators</a></li><li><a href="https://www.nice.org.uk/about/what-we-do/life-sciences" class="Services_link__jcE9g">Life sciences</a></li><li><a href="https://bnf.nice.org.uk/" class="Services_link__jcE9g">British National Formulary (BNF)</a></li><li><a href="https://bnfc.nice.org.uk/" class="Services_link__jcE9g">British National Formulary for Children (BNFC)</a></li><li><a href="https://cks.nice.org.uk/" class="Services_link__jcE9g">Clinical Knowledge Summaries (CKS)</a></li><li><a href="https://www.nice.org.uk/about/what-we-do/evidence-services/journals-and-databases" class="Services_link__jcE9g">Knowledge resources</a></li></ul></nav><nav class="Pages_wrapper__CzYGw"><ul class="Pages_list__VPm2s"><li><a href="https://www.nice.org.uk/about">About NICE</a></li><li><a href="https://www.nice.org.uk/about/what-we-do/into-practice">Into practice</a></li><li><a href="https://www.nice.org.uk/get-involved">Get involved with NICE</a></li><li><a href="https://www.nice.org.uk/get-involved/jobs">Jobs</a></li><li><a href="https://www.nice.org.uk/news">News</a></li><li><a href="https://www.nice.org.uk/news/nice-newsletters-and-alerts">Newsletters and alerts</a></li><li><a href="https://www.nice.org.uk/get-involved/contact-us">Contact us</a></li><li><a href="https://www.nice.org.uk/forms/leave-feedback">Leave feedback</a></li><li><a href="https://www.nice.org.uk/re-using-our-content">Reusing our content</a></li><li><a href="https://www.nice.org.uk/forms/use-of-nice-content-in-the-uk">NICE UK Open Content Licence</a></li><li><a href="https://www.nice.org.uk/about/what-we-do/nice-syndication-api">Syndicate our content</a></li><li><a href="https://www.nice.org.uk/events">Events</a></li></ul></nav><div class="Social_wrapper__V3V_U"><ul class="Social_list__rfQom" aria-label="NICE on social media"><li><a href="https://en-gb.facebook.com/NationalInstituteforHealthandCareExcellence/"><svg width="1em" height="1em" viewBox="0 0 512 512" fill="none" xmlns="http://www.w3.org/2000/svg" class="icon" aria-hidden="true" focusable="false"><path d="M291.069 178.811H361l-8.168 77.197h-61.778V480h-92.789V256.008H152v-77.197h46.265V132.32c0-32.983 7.802-57.95 23.407-74.897C237.276 40.474 262.949 32 298.689 32h61.778v77.196h-38.646c-7.071 0-12.74.589-17.006 1.766-4.267 1.177-7.351 3.309-9.25 6.394-1.9 3.085-3.124 6.211-3.673 9.377-.549 3.167-.823 7.652-.823 13.457v38.621Z" fill="currentColor"></path></svg>Facebook</a></li><li><a href="https://x.com/NICEcomms"><svg width="1em" height="1em" viewBox="0 0 1200 1227" fill="none" xmlns="http://www.w3.org/2000/svg" class="icon" aria-hidden="true" focusable="false"><path d="M714.163 519.284 1160.89 0h-105.86L667.137 450.887 357.328 0H0l468.492 681.821L0 1226.37h105.866l409.625-476.152 327.181 476.152H1200L714.137 519.284h.026ZM569.165 687.828l-47.468-67.894-377.686-540.24h162.604l304.797 435.991 47.468 67.894 396.2 566.721H892.476L569.165 687.854v-.026Z" fill="currentColor"></path></svg>X</a></li><li><a href="https://www.youtube.com/user/NICEmedia"><svg width="1em" height="1em" viewBox="0 0 512 512" fill="none" xmlns="http://www.w3.org/2000/svg" class="icon" aria-hidden="true" focusable="false"><path d="M209.753 314.5 330.746 252l-120.993-63.25V314.5ZM256 99c27.998 0 55.039.375 81.12 1.125 26.082.75 45.206 1.542 57.372 2.375l18.249 1c.167 0 1.584.125 4.25.375 2.667.25 4.583.5 5.75.75 1.166.25 3.125.625 5.874 1.125 2.75.5 5.125 1.167 7.125 2s4.333 1.917 7 3.25a48.044 48.044 0 0 1 7.749 4.875c2.5 1.917 4.917 4.125 7.25 6.625 1 1 2.291 2.542 3.875 4.625 1.583 2.083 3.999 6.958 7.249 14.625 3.25 7.667 5.458 16.083 6.625 25.25 1.333 10.667 2.375 22.042 3.125 34.125.75 12.083 1.208 21.542 1.375 28.375v44a529.498 529.498 0 0 1-4.5 72.5c-1.167 9.167-3.25 17.458-6.25 24.875-3 7.417-5.666 12.542-7.999 15.375l-3.5 4.25c-2.333 2.5-4.75 4.708-7.25 6.625-2.5 1.917-5.083 3.5-7.749 4.75-2.667 1.25-5 2.292-7 3.125-2 .833-4.375 1.5-7.125 2-2.749.5-4.749.875-5.999 1.125s-3.167.5-5.75.75-3.958.375-4.125.375C370.91 412.417 318.663 414 256 414c-34.498-.333-64.455-.875-89.87-1.625-25.415-.75-42.123-1.375-50.122-1.875l-12.25-1-8.999-1c-6-.833-10.541-1.667-13.624-2.5s-7.333-2.583-12.75-5.25c-5.416-2.667-10.124-6.083-14.124-10.25-1-1-2.291-2.542-3.875-4.625-1.583-2.083-4-6.958-7.25-14.625-3.249-7.667-5.457-16.083-6.624-25.25-1.333-10.667-2.375-22.042-3.125-34.125-.75-12.083-1.208-21.542-1.374-28.375v-44a529.323 529.323 0 0 1 4.5-72.5c1.166-9.167 3.25-17.458 6.249-24.875 3-7.417 5.666-12.542 8-15.375l3.5-4.25c2.332-2.5 4.749-4.708 7.249-6.625A48.018 48.018 0 0 1 69.26 111c2.666-1.333 5-2.417 6.999-3.25 2-.833 4.375-1.5 7.125-2s4.708-.875 5.874-1.125c1.167-.25 3.084-.5 5.75-.75s4.083-.375 4.25-.375C141.09 100.5 193.337 99 256 99Z" fill="currentColor"></path></svg>YouTube</a></li><li><a href="https://www.linkedin.com/company/national-institute-for-health-and-clinical-excellence"><svg width="1em" height="1em" viewBox="0 0 512 512" fill="none" xmlns="http://www.w3.org/2000/svg" class="icon" aria-hidden="true" focusable="false"><path d="M134.024 181.394v289.59H37.565v-289.59h96.459Zm6.138-89.416c.196 14.226-4.725 26.112-14.764 35.658-10.039 9.546-23.243 14.319-39.612 14.319h-.589c-15.975 0-28.835-4.773-38.58-14.319C36.872 118.09 32 106.204 32 91.978c0-14.412 5.02-26.347 15.059-35.806C57.099 46.713 70.204 41.989 86.376 42c16.172.01 29.13 4.735 38.874 14.172 9.745 9.437 14.716 21.372 14.912 35.806Zm340.822 213.035V471H384.82V316.125c0-20.456-3.945-36.483-11.835-48.08-7.889-11.597-20.215-17.395-36.976-17.395-12.276 0-22.555 3.36-30.838 10.08-8.282 6.721-14.469 15.05-18.561 24.989-2.139 5.848-3.209 13.736-3.209 23.663v161.602h-96.164c.393-77.733.59-140.758.59-189.078 0-48.319-.099-77.154-.295-86.503l-.295-14.025h96.164v42.074h-.589c3.896-6.23 7.89-11.685 11.982-16.365 4.092-4.68 9.597-9.748 16.515-15.203 6.919-5.455 15.398-9.693 25.437-12.715 10.039-3.022 21.197-4.533 33.473-4.533 33.326 0 60.121 11.057 80.385 33.171C470.868 229.921 481 262.312 481 304.98l-.016.033Z" fill="currentColor"></path></svg>LinkedIn</a></li></ul></div></div><div class="Legal_wrapper__aXhHi"><div class="Legal_container__5nLdZ"><nav class="Legal_menu__L03tj" aria-label="Legal menu"><ul><li><a href="https://www.nice.org.uk/accessibility">Accessibility</a></li><li><a href="https://www.nice.org.uk/freedom-of-information">Freedom of information</a></li><li><a href="https://www.nice.org.uk/glossary">Glossary</a></li><li><a href="https://www.nice.org.uk/terms-and-conditions">Terms and conditions</a></li><li><a href="https://www.nice.org.uk/privacy-notice">Privacy notice</a></li><li><a href="https://www.nice.org.uk/cookies">Cookies</a></li></ul></nav><p class="Legal_copyright__Vn3GT">©<!-- --> <abbr title="National Institute for Health and Care Excellence">NICE</abbr> <!-- -->2024<!-- -->. All rights reserved. Subject to<!-- --> <a href="https://www.nice.org.uk/terms-and-conditions#notice-of-rights">Notice of rights</a>.</p></div></div></footer></div></div><script id="__NEXT_DATA__" type="application/json">{"props":{"pageProps":{"story":{"name":"New study shows NICE Advice support can reduce appraisal timelines by 3 months","created_at":"2024-11-14T07:49:45.669Z","published_at":"2024-11-14T09:58:42.160Z","alternates":[],"id":578772127,"uuid":"622fa496-a7dd-4375-94da-e19ccf3f6907","content":{"_uid":"3336a877-c03b-40a1-bfe6-49f75c00e267","date":"2024-11-14 00:00","image":{"id":18425808,"alt":"","name":"","focus":"","title":"","source":"","filename":"https://a.storyblok.com/f/243782/2495x1201/766442ac9a/perscription-being-delivered-to-a-patient-at-home.jpg","copyright":"","fieldtype":"asset","meta_data":{},"is_external_url":false},"title":"New study shows NICE Advice support can reduce appraisal timelines by 3 months","content":{"type":"doc","content":[{"type":"paragraph","content":[{"text":"The research","type":"text","marks":[{"type":"link","attrs":{"href":"https://www.ispor.org/conferences-education/conferences/upcoming-conferences/ispor-europe-2024/program/program/paper/euro2024-4008/19100/the-value-of-nice-scientific-advice","uuid":null,"anchor":null,"target":null,"linktype":"url"}},{"type":"textStyle","attrs":{"color":""}}]},{"text":", which will be presented to delegates at the ISPOR conference in Barcelona, Spain, examined NICE technology appraisal and highly specialised technologies guidance published between June 2020 and May 2023. It found that products benefiting from NICE Advice’s scientific advice service had a shorter time from marketing authorisation to the publication of NICE guidance.","type":"text","marks":[{"type":"textStyle","attrs":{"color":""}}]},{"type":"hard_break"},{"type":"hard_break"},{"text":"According to the study, technologies that received scientific advice took a median of 312 days to progress from marketing authorisation to NICE guidance publication. In contrast, those without such advice required a median of 400 days – a difference of nearly 3 months.","type":"text","marks":[{"type":"textStyle","attrs":{"color":""}}]},{"type":"hard_break"},{"type":"hard_break"},{"text":"The analysis included 230 technology appraisal and highly specialised technologies guidance documents, of which 51 technologies had received scientific advice from NICE Advice. While the study acknowledges that various factors can influence the time to guidance publication, the majority of these would be expected to apply to technologies with or without scientific advice.","type":"text","marks":[{"type":"textStyle","attrs":{"color":""}}]}]},{"type":"blok","attrs":{"id":"8316733d-835e-4a6f-936e-27ac0435434a","body":[{"_uid":"i-be244960-b69b-464e-8969-d4c937ac0ab8","component":"quote","quoteText":{"type":"doc","content":[{"type":"paragraph","content":[{"text":"This study reinforces the value of engaging with NICE Advice’s scientific advice service early in the product development process. Our depth of knowledge and unique insights can help companies effectively prepare for their NICE evaluation, potentially streamlining their path through the process, and helping to get innovative technologies to patients faster.","type":"text"}]}]},"quoteAuthor":"Andrew Walsh, associate director of NICE Advice"}]}},{"type":"paragraph","content":[{"text":"The results support ","type":"text"},{"text":"previous findings","type":"text","marks":[{"type":"link","attrs":{"href":"https://www.valueinhealthjournal.com/article/S1098-3015(20)33008-4/fulltext","uuid":null,"anchor":null,"target":null,"linktype":"url"}}]},{"text":" on the benefits of NICE Advice’s scientific advice service. This earlier study showed that between 2009 and 2019, the median time from marketing authorisation to publication of NICE guidance was 296 days for products that used NICE Advice’s scientific advice service compared to 405 days for products that did not.","type":"text"},{"type":"hard_break"},{"type":"hard_break"},{"text":"As the life sciences sector continues to innovate, our independent and highly confidential support service, ","type":"text"},{"text":"NICE Advice","type":"text","marks":[{"type":"link","attrs":{"href":"https://www.nice.org.uk/about/what-we-do/life-sciences/nice-advice-service","uuid":null,"anchor":null,"target":null,"linktype":"url"}}]},{"text":", offers a valuable resource to companies aiming to speed up the NICE appraisal process and get their new treatments to NHS patients faster. By partnering with NICE Advice, companies can ensure their technologies meet NHS needs from the early stages of development, guiding them in collecting high-quality evidence that resonates with decision-makers.","type":"text"}]}]},"metadata":[],"component":"newsArticle","introText":"Companies who receive scientific advice from our NICE Advice service may experience a faster path to guidance publication, a study has found. ","resources":[{"_uid":"3f064c04-f11b-4eca-9949-8b0af7de6c04","link":{"id":"","url":"https://www.nice.org.uk/about/what-we-do/life-sciences/nice-advice-service","linktype":"url","fieldtype":"multilink","cached_url":"https://www.nice.org.uk/about/what-we-do/life-sciences/nice-advice-service"},"title":"NICE Advice","component":"relatedLink"},{"_uid":"a0444453-7388-496d-92a2-c14ab504974a","link":{"id":"","url":"https://www.ispor.org/conferences-education/conferences/upcoming-conferences/ispor-europe-2024/program/program/paper/euro2024-4008/19100/the-value-of-nice-scientific-advice","linktype":"url","fieldtype":"multilink","cached_url":"https://www.ispor.org/conferences-education/conferences/upcoming-conferences/ispor-europe-2024/program/program/paper/euro2024-4008/19100/the-value-of-nice-scientific-advice"},"title":"The value of NICE scientific advice","component":"relatedLink"}],"relatedNews":[]},"slug":"new-study-shows-nice-advice-support-can-reduce-appraisal-timelines-by-3-months","full_slug":"news/articles/new-study-shows-nice-advice-support-can-reduce-appraisal-timelines-by-3-months","default_full_slug":null,"sort_by_date":null,"position":-2200,"tag_list":[],"is_startpage":false,"parent_id":420552799,"meta_data":null,"group_id":"e04b4626-7880-4a76-a1a4-bcd8cf42397b","first_published_at":"2024-11-14T07:54:04.336Z","release_id":null,"lang":"default","path":null,"translated_slugs":[]},"breadcrumbs":[{"title":"Home","path":"/"},{"title":"News","path":"/news"},{"title":"News articles","path":"/news/articles"}]},"__N_SSP":true},"page":"/news/articles/[slug]","query":{"slug":"new-study-shows-nice-advice-support-can-reduce-appraisal-timelines-by-3-months"},"buildId":"nPtE9ZhzdAiprqYEkzKqu","runtimeConfig":{"buildNumber":"10.0.2148+r5C25139","environment":"live","authEnvironment":"live","baseURL":"https://www.nice.org.uk","cookieBannerScriptURL":"https://cdn.nice.org.uk/cookie-banner/cookie-banner.min.js","publicBaseURL":"","search":{"baseURL":"https://search-api.nice.org.uk/api"},"cacheControl":{"defaultCacheHeader":"public, s-max-age=300, max-age=120, stale-while-revalidate=1800"},"jotForm":{"baseURL":"https://nice.jotform.com"},"storyblok":{"accessToken":"rFI0YRpDyqZpxXvUhbJB3gtt","ocelotEndpoint":"https://next-web-api.nice.org.uk/storyblok","enableRootCatchAll":false},"denyRobots":false,"nodeConfigServerKey":"server","nodeConfigPublicKey":"public"},"isFallback":false,"isExperimentalCompile":false,"gssp":true,"scriptLoader":[]}</script></body></html>