Cancer Pathways: R&D Systems

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</div> <div class="pw_header"> <h1>Cancer Pathways</h1> </div> <div class="FtPthwy"> <div class="container-fluid"> <div class="row"> <div class="col-xs-12 col-sm-12 col-md-6 col-md-push-6"> <div class="FtPthwyTn"> <a href="/pathways/fgf-signaling-pathways"><img width="100%" class="img-responsive" alt="FGF Family Signaling Pathways" src="//resources.rndsystems.com/images/Pathways/Thumbnails/dv_pathways_fgf-family-signaling-pathways-thumb.png?v=1"></a> </div> </div> <div class="col-xs-12 col-sm-12 col-md-6 col-md-pull-6"> <h4 class="FtPthwyH4"> Featured Pathway - FGF Family Signaling Pathways </h4> <p>The illustration shows the intracellular signaling pathways that are induced following FGF receptor activation. Interact with the illustration to see additional information about the members of the different FGF subfamilies, their reported receptor binding specificities and physiological functions, and the pathologies associated with mutation or amplification of different FGFs.</p> <p> <a class="btn btn-tertiary btn-ftpthwy" href="/pathways/fgf-signaling-pathways">View Pathway</a> </p> </div> </div> </div> </div> <div class="pw_categories"> <h2>Interactive Pathways by Category</h2> <div class="row"> <div class="col-xs-12"> <div class="pw_categories"> <div class="row PathwayViewCon"> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_autophagy_pathway" action="/pathways/autophagy-pathway" method="post"> <a href="/pathways/autophagy-pathway" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/autophagy-pathway.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_autophagy_pathway"> <h2 class="pw_category_title">Autophagy Pathway</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_chemokine_signaling_pathways" action="/pathways/chemokine-signaling-pathways" method="post"> <a href="/pathways/chemokine-signaling-pathways" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/chemokine-signaling-pathways-thumb.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_chemokine_signaling_pathways"> <h2 class="pw_category_title">Chemokine Signaling Pathways</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_fgf_family_signaling_pathways" action="/pathways/fgf-signaling-pathways" method="post"> <a href="/pathways/fgf-signaling-pathways" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/dv_pathways_fgf-family-signaling-pathways-thumb.png?v=1" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_fgf_family_signaling_pathways"> <h2 class="pw_category_title">FGF Family Signaling Pathways</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_hif_enhancer_pathways" action="/pathways/hif-enhancer-pathways" method="post"> <a href="/pathways/hif-enhancer-pathways" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/hif-enhancers.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_hif_enhancer_pathways"> <h2 class="pw_category_title">HIF Enhancer Pathways</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_hif_repressor_pathways" action="/pathways/hif-repress-pathways" method="post"> <a href="/pathways/hif-repress-pathways" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/hif-repressors.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_hif_repressor_pathways"> <h2 class="pw_category_title">HIF Repressor Pathways</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_hif_stability_and_activity_pathways" action="/pathways/hif-stability-activity-pathways" method="post"> <a href="/pathways/hif-stability-activity-pathways" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/hif-stability-activity.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_hif_stability_and_activity_pathways"> <h2 class="pw_category_title">HIF Stability and Activity Pathways</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_mdsc_mediated_mechanisms_of_immunosuppression" action="/pathways/mdsc-mediated-mechanisms-of-immunosuppression" method="post"> <a href="/pathways/mdsc-mediated-mechanisms-of-immunosuppression" data-src="http://resources.rndsystems.com/images/Pathways/Thumbnails/mdsc-pathways-700x305.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_mdsc_mediated_mechanisms_of_immunosuppression"> <h2 class="pw_category_title">MDSC-Mediated Mechanisms of Immunosuppression</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_mechanisms_of_regulatory_t_cell_mediated_suppression" action="/pathways/mechanisms-of-regulatory-t-cell-mediated-suppression" method="post"> <a href="/pathways/mechanisms-of-regulatory-t-cell-mediated-suppression" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/mechanisms-of-regulatory-t-cell-pathways-250x109-LG.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_mechanisms_of_regulatory_t_cell_mediated_suppression"> <h2 class="pw_category_title">Mechanisms of Regulatory T Cell-Mediated Suppression</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_mechanisms_of_tumor_associated_macrophage_tam_mediated_immunosuppression" action="/pathways/tumor-associated-macrophage-tam" method="post"> <a href="/pathways/tumor-associated-macrophage-tam" data-src="https://resources.rndsystems.com/images/Pathways/Thumbnails/tam-pathways-700x269.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_mechanisms_of_tumor_associated_macrophage_tam_mediated_immunosuppression"> <h2 class="pw_category_title">Mechanisms of Tumor-Associated Macrophage TAM-Mediated Immunosuppression</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_mechanisms_of_tumor_derived_exosome_tex_mediated_immunosuppression" action="/pathways/mechanisms-tumor-derived-exosome-tex-mediated-immunosuppression" method="post"> <a href="/pathways/mechanisms-tumor-derived-exosome-tex-mediated-immunosuppression" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/tex-pathway-700x269.jpg" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_mechanisms_of_tumor_derived_exosome_tex_mediated_immunosuppression"> <h2 class="pw_category_title">Mechanisms of Tumor-derived Exosome TEX-mediated Immunosuppression</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_mtor_signaling_pathway" action="/pathways/mtor-signaling-pathway" method="post"> <a href="/pathways/mtor-signaling-pathway" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/mtor-signaling.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_mtor_signaling_pathway"> <h2 class="pw_category_title">mTOR Signaling Pathway</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_natural_killer_cell_receptors__human_target_cell_–_nk_cell_ligand_receptor_interactions" action="/pathways/natural-killer-cell-receptors-human-target-cell-nk-cell-ligand-receptor-interactions-pathway" method="post"> <a href="/pathways/natural-killer-cell-receptors-human-target-cell-nk-cell-ligand-receptor-interactions-pathway" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/250x109_nkcells_tn.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_natural_killer_cell_receptors__human_target_cell_–_nk_cell_ligand_receptor_interactions"> <h2 class="pw_category_title">Natural Killer Cell Receptors: Human Target Cell – NK Cell Ligand-Receptor Interactions</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_organelle_markers_pathway__ihc_icc" action="/pathways/organelle-markers-pathway-ihc-icc" method="post"> <a href="/pathways/organelle-markers-pathway-ihc-icc" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/organelle-markers-ihc-icc.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_organelle_markers_pathway__ihc_icc"> <h2 class="pw_category_title">Organelle Markers Pathway: IHC/ICC</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_p53_pathway" action="/pathways/p53-pathway" method="post"> <a href="/pathways/p53-pathway" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/p53-pathway.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_p53_pathway"> <h2 class="pw_category_title">p53 Pathway</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_t_cell_co_signaling_pathway__ligand_receptor_interactions" action="/pathways/t-cell-co-signaling-pathway-lig-recept-interactions" method="post"> <a href="/pathways/t-cell-co-signaling-pathway-lig-recept-interactions" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/t-cell-co-signaling-tn4.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_t_cell_co_signaling_pathway__ligand_receptor_interactions"> <h2 class="pw_category_title">T Cell Co-Signaling Pathway: Ligand-Receptor Interactions</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_tgf_beta_signaling_pathways" action="/pathways/tgf-beta-signaling-pathways" method="post"> <a href="/pathways/tgf-beta-signaling-pathways" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/tgf-beta-signaling-pathways.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_tgf_beta_signaling_pathways"> <h2 class="pw_category_title">TGF-beta Signaling Pathways</h2> </a> <input type="hidden" name="pw_parent" value="Cancer"> </form> </div> </div> <div class="pw_category col-xs-12 col-sm-6"> <div class="pw_category_wrapper"> <form id="ind_pathways_vegf___vegf_r2_signaling_pathways" action="/pathways/vegf-vegf-r2-signaling-pathways" method="post"> <a href="/pathways/vegf-vegf-r2-signaling-pathways" data-src="//resources.rndsystems.com/images/Pathways/Thumbnails/vegf-vegf-r2-signaling-pathways.png" class="b-lazy toplevel pw_category_link pw_category_wrapper_single pathway_link" data-form="ind_pathways_vegf___vegf_r2_signaling_pathways"> <h2 class="pw_category_title">VEGF - VEGF R2 Signaling Pathways</h2> </a> <input 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