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title=\"Википедија:Уређивачки маратон Вики воли споменике 2024.\"\u003EУређивачки маратон Вики воли споменике 2024\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EУ току је такмичење у писању чланака на 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2024\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EУчествујте у \u003Cb\u003E\u003Ca href=\"https://sr.wikiquote.org/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D1%86%D0%B8%D1%82%D0%B0%D1%82:%D0%9A%D0%B0%D0%BC%D0%BF%D0%B0%D1%9A%D0%B0_SheSaid_2024\" class=\"extiw\" title=\"q:Викицитат:Кампања SheSaid 2024\"\u003Eкампањи писања цитата значајних жена\u003C/a\u003E\u003C/b\u003E на Викицитату.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\n\u003Cdiv class=\"noticebanner\"\u003E\u003Cdiv class=\"plainlinks\" style=\"background-color: #FBEBEA; border-radius:5px; margin-top:10px; position:relative; border: 1px solid #aaa; font-family: \u0026#39;Helvetica\u0026#39;, \u0026#39;Arial\u0026#39;, sans-serif; line-height: 18px; box-shadow: 0 1px 1px rgba( 0, 0, 0, 0.15 ); overflow:hidden;\"\u003E\u003Cdiv style=\"display:block; top:4px; width:100%; text-align:center;;\"\u003E\u003Cdiv style=\"color:#000085; font-size:25px; line-height:25px\"\u003E\u003Cdiv style=\"padding-left:50px;\"\u003E\u003C/div\u003E\u003C/div\u003E\u003Cdiv style=\"padding-top:2px; color:#444; font-size:1.15em; line-height:1.5;\"\u003E\u003Cdiv style=\"padding-left:8px; padding-right:8px;\"\u003EПридружите се \u003Cb\u003E\u003Ca href=\"/wiki/%D0%92%D0%B8%D0%BA%D0%B8%D0%BF%D0%B5%D0%B4%D0%B8%D1%98%D0%B0:%D0%90%D0%BA%D1%86%D0%B8%D1%98%D0%B0_%D0%BF%D1%80%D0%BE%D1%88%D0%B8%D1%80%D0%B8%D0%B2%D0%B0%D1%9A%D0%B0_%D0%BA%D0%BB%D0%B8%D1%86%D0%B0\" title=\"Википедија:Акција проширивања клица\"\u003Eакцији проширивања клица\u003C/a\u003E\u003C/b\u003E.\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E\u003C/div\u003E";}}());</script></div> </div> <div class="vector-column-start"> <div class="vector-main-menu-container"> <div id="mw-navigation"> <nav id="mw-panel" class="vector-main-menu-landmark" aria-label="Сајт"> <div id="vector-main-menu-pinned-container" class="vector-pinned-container"> </div> </nav> </div> </div> </div> <div class="mw-content-container"> <main id="content" class="mw-body"> <header class="mw-body-header vector-page-titlebar"> <h1 id="firstHeading" class="firstHeading mw-first-heading">Извор странице Amfotericin B</h1> <div id="p-lang-btn" class="vector-dropdown mw-portlet mw-portlet-lang" > <input type="checkbox" id="p-lang-btn-checkbox" role="button" aria-haspopup="true" data-event-name="ui.dropdown-p-lang-btn" class="vector-dropdown-checkbox mw-interlanguage-selector" aria-label="Овај чланак постоји само на овом језику. Додајте друге језике." > <label id="p-lang-btn-label" for="p-lang-btn-checkbox" class="vector-dropdown-label cdx-button cdx-button--fake-button cdx-button--fake-button--enabled cdx-button--weight-quiet cdx-button--action-progressive mw-portlet-lang-heading-0" aria-hidden="true" ><span class="vector-icon mw-ui-icon-language-progressive mw-ui-icon-wikimedia-language-progressive"></span> <span class="vector-dropdown-label-text">Додај језике</span> </label> <div class="vector-dropdown-content"> <div class="vector-menu-content"> <ul class="vector-menu-content-list"> </ul> <div class="after-portlet after-portlet-lang"><span class="uls-after-portlet-link"></span></div> </div> </div> </div> </header> <div class="vector-page-toolbar"> <div class="vector-page-toolbar-container"> <div id="left-navigation"> <nav aria-label="Именски простори"> <div id="p-associated-pages" class="vector-menu vector-menu-tabs mw-portlet mw-portlet-associated-pages" > <div class="vector-menu-content"> <ul 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Можете такође послати мејл <a href="https://meta.wikimedia.org/wiki/Special:MyLanguage/Stewards" class="extiw" title="m:Special:MyLanguage/Stewards">стјуардима</a> <a href="https://meta.wikimedia.org/wiki/Special:MyLanguage/VRT" class="extiw" title="m:Special:MyLanguage/VRT">VRT</a>-а на <kbd>stewards@wikimedia.org</kbd>; обавезно наведите све горње податке.</div></div><hr /> <p>Можете да видите и копирате извор ове странице. </p><textarea readonly="" accesskey="," id="wpTextbox1" cols="80" rows="25" style="" class="mw-editfont-monospace" lang="sr" dir="ltr" name="wpTextbox1">{{Drugbox-lat | IUPAC_name = | image = Amphotericin B new.svg | width = | alt = | image2 =Amphotericin_b.png | width2 = | alt2 = | caption = | drug_name = Amfotericin B | caption =  | tradename = -{Abelcet, ABLC, AmBisome, Ampho-Moronal}- | Drugs.com = {{drugs.com-lat|monograph|Amphotericin B}} | MedlinePlus = | licence_EU = | licence_US = | DailyMedID = | pregnancy_AU = | pregnancy_US = | pregnancy_category= | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | dependency_liability = | routes_of_administration = Intravenozno  | bioavailability = | protein_bound = | metabolism = | elimination_half-life = 15 dana | excretion =  | CAS_number_Ref = {{cascite|correct|}} | CAS_number = 1397-89-3 | CAS_supplemental = | ATCvet = | ATC_prefix = A01 | ATC_suffix = AB04 | ATC_supplemental = , {{ATC|J02|AA01}} | PubChem = 5280965 | PubChemSubstance = 46505473 | IUPHAR_ligand = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB00681 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 14245 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = C06573 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 267345 | synonyms =  |C=47 |H=73 |N=1 |O=17 | molecular_weight = 924,079 | smiles = [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2 | StdInChI = 1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChI_comment = | StdInChIKey = APKFDSVGJQXUKY-INPOYWNPSA-N | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | density = | melting_point = 170.0 | melting_high = | melting_notes = | boiling_point = | boiling_notes = | solubility = | specific_rotation = | sec_combustion = }} '''Amfotericin B''' je [[organsko jedinjenje]], koje sadrži 47 [[atom]]a [[ugljenik]]a i ima [[Молекулска маса|molekulsku masu]] od 924,079 [[Јединица атомске масе|-{Da}-]].<ref>{{Cite pmid|21059682|noedit}}</ref><ref>{{cite pmid|18048412|noedit}}</ref> == Osobine == {| class="wikitable sortable" |- ! Osobina !! Vrednost |- | [[Водонична веза|Broj akceptora vodonika]] || 18 |- | [[Водонична веза|Broj donora vodonika]] || 12 |- | [[Геометрија молекула|Broj rotacionih veza]] || 3 |- | [[Particioni koeficijent]]<ref>{{cite doi/10.1021/jp980230o|noedit}}</ref> (-{''ALogP'')}- || -2,6 |- | [[Rastvorljivost]]<ref>{{cite pmid|11749573|noedit}}</ref> (-{''logS'', log(''mol/L''}-)) || -7,8 |- | [[Polarna površina molekula|Polarna površina]]<ref>{{cite pmid|11020286|noedit}}</ref> (-{''PSA''}-, [[Ангстрем (јединица)|Å<sup>2</sup>]]) || 319,6 |} == Reference == {{reflist}} == Literatura == {{Литература}} * {{GoodmanGilman10th}} * {{FoyePrinciplesMedChem6th}} {{Литература крај}} == Spoljašnje veze == * [http://www.drugbank.ca/drugs/DB00681 -{Amphotericin B}-] {{Medicinsko upozorenje-lat}} {{Podnožje|lat=da|Medicina|Hemija}} {{СОРТИРАЊЕ:Амфотерицин Б}} [[Категорија:Антибиотици]] [[Категорија:Антимикотици]] [[Категорија:Антипротозоици]] [[Категорија:Алкохоли]] [[Категорија:Карбоксилне киселине‎]] 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