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overflow: hidden; text-overflow: ellipsis; -webkit-line-clamp: 3; -webkit-box-orient: vertical; }</style><div class="col-xs-12 clearfix"><div class="u-floatLeft"><h1 class="PageHeader-title u-m0x u-fs30">Nuclear medicine</h1><div class="u-tcGrayDark">14,821 Followers</div><div class="u-tcGrayDark u-mt2x">Recent papers in <b>Nuclear medicine</b></div></div></div></div></div></div><div class="TabbedNavigation"><div class="container"><div class="row"><div class="col-xs-12 clearfix"><ul class="nav u-m0x u-p0x list-inline u-displayFlex"><li class="active"><a href="https://www.academia.edu/Documents/in/Nuclear_medicine">Top Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Nuclear_medicine/MostCited">Most Cited Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Nuclear_medicine/MostDownloaded">Most Downloaded Papers</a></li><li><a href="https://www.academia.edu/Documents/in/Nuclear_medicine/MostRecent">Newest Papers</a></li><li><a class="" href="https://www.academia.edu/People/Nuclear_medicine">People</a></li></ul></div><style type="text/css">ul.nav{flex-direction:row}@media(max-width: 567px){ul.nav{flex-direction:column}.TabbedNavigation li{max-width:100%}.TabbedNavigation li.active{background-color:var(--background-grey, #dddde2)}.TabbedNavigation li.active:before,.TabbedNavigation li.active:after{display:none}}</style></div></div></div><div class="container"><div class="row"><div class="col-xs-12"><div class="u-displayFlex"><div class="u-flexGrow1"><div class="works"><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23227070" data-work_id="23227070" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23227070/The_potential_impact_of_the_resource_based_relative_value_scale_on_the_practice_of_nuclear_medicine">The potential impact of the resource-based relative value scale on the practice of nuclear medicine</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The Resource-Based Relative Value Scale IRBRVS) is finally here. A system designed to equate physician work across the specialties, it has its own peculiar and unique problems. Modeling of the system was based on the single... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_23227070" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The Resource-Based Relative Value Scale IRBRVS) is finally here. A system designed to equate physician work across the specialties, it has its own peculiar and unique problems. Modeling of the system was based on the single physician-patient interaction; it may not work properly for laboratory specialties. There are other unique considerations concerning how the model was constructed. Although data were collected specifically for nuclear medicine, they were not used in the final computations. There is disagreement over whether those data would benefit or hurt nuclear medicine reimbursement. As presently implemented, the RBRVS poses grave dangers for the future of nuclear medicine. These dangers come not only in the professional reimbursement section of the rules but in the technical component areas as well. Estimates for reduction of income by 1996 range as high as 55% for nuclear medicine. When one factors the implementation of the RBRVS by independent insurance carriers into the equation, the entire economic future becomes muddy, A brief historical review of the RBRVS, as well as discussion of potential future implications of this type of reimbursement system, is presented. Prognostication is at least as inexact a science as reimbursement. Hopefully, the author's outlook on the future of nuclear medicine is more pessimistic than it need be.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23227070" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="9c4ff4e34273a42bc1dc647d81bc32b6" rel="nofollow" data-download="{"attachment_id":43713974,"asset_id":23227070,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43713974/download_file?st=MTc0MDU3MDk0OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="42736653" href="https://independent.academia.edu/RobertHenkin">Robert Henkin</a><script data-card-contents-for-user="42736653" type="text/json">{"id":42736653,"first_name":"Robert","last_name":"Henkin","domain_name":"independent","page_name":"RobertHenkin","display_name":"Robert Henkin","profile_url":"https://independent.academia.edu/RobertHenkin?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_23227070 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="23227070"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 23227070, container: ".js-paper-rank-work_23227070", }); });</script></li><li class="js-percentile-work_23227070 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 23227070; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_23227070"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_23227070 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="23227070"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 23227070; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=23227070]").text(description); $(".js-view-count-work_23227070").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_23227070").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="23227070"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="98134" rel="nofollow" href="https://www.academia.edu/Documents/in/United_States">United States</a>, <script data-card-contents-for-ri="98134" type="text/json">{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="218342" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicare">Medicare</a>, <script data-card-contents-for-ri="218342" type="text/json">{"id":218342,"name":"Medicare","url":"https://www.academia.edu/Documents/in/Medicare?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="235072" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicaid">Medicaid</a><script data-card-contents-for-ri="235072" type="text/json">{"id":235072,"name":"Medicaid","url":"https://www.academia.edu/Documents/in/Medicaid?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=23227070]'), work: {"id":23227070,"title":"The potential impact of the resource-based relative value scale on the practice of nuclear medicine","created_at":"2016-03-14T06:02:01.393-07:00","url":"https://www.academia.edu/23227070/The_potential_impact_of_the_resource_based_relative_value_scale_on_the_practice_of_nuclear_medicine?f_ri=10035","dom_id":"work_23227070","summary":"The Resource-Based Relative Value Scale IRBRVS) is finally here. A system designed to equate physician work across the specialties, it has its own peculiar and unique problems. Modeling of the system was based on the single physician-patient interaction; it may not work properly for laboratory specialties. There are other unique considerations concerning how the model was constructed. Although data were collected specifically for nuclear medicine, they were not used in the final computations. There is disagreement over whether those data would benefit or hurt nuclear medicine reimbursement. As presently implemented, the RBRVS poses grave dangers for the future of nuclear medicine. These dangers come not only in the professional reimbursement section of the rules but in the technical component areas as well. Estimates for reduction of income by 1996 range as high as 55% for nuclear medicine. When one factors the implementation of the RBRVS by independent insurance carriers into the equation, the entire economic future becomes muddy, A brief historical review of the RBRVS, as well as discussion of potential future implications of this type of reimbursement system, is presented. Prognostication is at least as inexact a science as reimbursement. Hopefully, the author's outlook on the future of nuclear medicine is more pessimistic than it need be.","downloadable_attachments":[{"id":43713974,"asset_id":23227070,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":42736653,"first_name":"Robert","last_name":"Henkin","domain_name":"independent","page_name":"RobertHenkin","display_name":"Robert Henkin","profile_url":"https://independent.academia.edu/RobertHenkin?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":98134,"name":"United States","url":"https://www.academia.edu/Documents/in/United_States?f_ri=10035","nofollow":true},{"id":218342,"name":"Medicare","url":"https://www.academia.edu/Documents/in/Medicare?f_ri=10035","nofollow":true},{"id":235072,"name":"Medicaid","url":"https://www.academia.edu/Documents/in/Medicaid?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":602889,"name":"Cost Control","url":"https://www.academia.edu/Documents/in/Cost_Control?f_ri=10035"},{"id":906536,"name":"Health Care Costs","url":"https://www.academia.edu/Documents/in/Health_Care_Costs?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17848654" data-work_id="17848654" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17848654/Enhanced_Detection_of_Viable_Myocardiumby_Technetium99m_MIBIImaging_after_Nitrate_Administration_in_Chronic_Coronary">Enhanced Detection of Viable Myocardiumby Technetium99m-MIBIImaging after Nitrate Administration in Chronic Coronary</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Theaimof this studywasto assesswhethernitrateadministra tion improvesthe imagingcapabilitiesof @Â°â€˜Tc-MlBl tomogra phy in detectingviablemyocardiumin coronaryarterydisease (CAD). Methods: Thirty-one patients withangiographically proven... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_17848654" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Theaimof this studywasto assesswhethernitrateadministra tion improvesthe imagingcapabilitiesof @Â°â€˜Tc-MlBl tomogra phy in detectingviablemyocardiumin coronaryarterydisease (CAD). Methods: Thirty-one patients withangiographically proven CADand chronicLV dysfunction(ejectionfraction39% Â±9%) underwenttwo @Â°â€˜Tc-MlBl studieson separatedays:oneunder rest conditionsand the other after nitroglycerine(0.005mg/kg per Os)administration.Within1 wk, all patientsalso underwent rest-redistribution 2o1@fl imaging. Eightpatients werealsostud ied by echocardiography before and 5 Â±3 mo after coronary revascularization. Results: On resting 99mTc.MlBl im ages, 302 segmentshad normal uptake, 183 segmentshad moderatelyreduceduptakeand 197 had severelyreducedup take. Of the segmentswith severelyreduceduptake,54 (27%) had increased uptake after nitroglycerineand were viable on 201fl images. Of the 143 (73%) segmentswith severely reduced @Â°Tc-MlBl uptakeand no changeafternitroglycerine, 81% werenonvi...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17848654" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7f0cda5dafca23ec66b20f25939ab5d0" rel="nofollow" data-download="{"attachment_id":39742582,"asset_id":17848654,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/39742582/download_file?st=MTc0MDU3MDk0OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37765334" href="https://independent.academia.edu/SimoneMaurea">Simone Maurea</a><script data-card-contents-for-user="37765334" type="text/json">{"id":37765334,"first_name":"Simone","last_name":"Maurea","domain_name":"independent","page_name":"SimoneMaurea","display_name":"Simone Maurea","profile_url":"https://independent.academia.edu/SimoneMaurea?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_17848654 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="17848654"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 17848654, container: ".js-paper-rank-work_17848654", }); });</script></li><li class="js-percentile-work_17848654 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17848654; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_17848654"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_17848654 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="17848654"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17848654; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17848654]").text(description); $(".js-view-count-work_17848654").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_17848654").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="17848654"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">11</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="46824" rel="nofollow" href="https://www.academia.edu/Documents/in/Echocardiography">Echocardiography</a>, <script data-card-contents-for-ri="46824" type="text/json">{"id":46824,"name":"Echocardiography","url":"https://www.academia.edu/Documents/in/Echocardiography?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="131495" rel="nofollow" href="https://www.academia.edu/Documents/in/Heart">Heart</a>, <script data-card-contents-for-ri="131495" type="text/json">{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="167876" rel="nofollow" href="https://www.academia.edu/Documents/in/Myocardial_Revascularization">Myocardial Revascularization</a><script data-card-contents-for-ri="167876" type="text/json">{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17848654]'), work: {"id":17848654,"title":"Enhanced Detection of Viable Myocardiumby Technetium99m-MIBIImaging after Nitrate Administration in Chronic Coronary","created_at":"2015-11-06T01:29:13.161-08:00","url":"https://www.academia.edu/17848654/Enhanced_Detection_of_Viable_Myocardiumby_Technetium99m_MIBIImaging_after_Nitrate_Administration_in_Chronic_Coronary?f_ri=10035","dom_id":"work_17848654","summary":"Theaimof this studywasto assesswhethernitrateadministra tion improvesthe imagingcapabilitiesof @Â°â€˜Tc-MlBl tomogra phy in detectingviablemyocardiumin coronaryarterydisease (CAD). Methods: Thirty-one patients withangiographically proven CADand chronicLV dysfunction(ejectionfraction39% Â±9%) underwenttwo @Â°â€˜Tc-MlBl studieson separatedays:oneunder rest conditionsand the other after nitroglycerine(0.005mg/kg per Os)administration.Within1 wk, all patientsalso underwent rest-redistribution 2o1@fl imaging. Eightpatients werealsostud ied by echocardiography before and 5 Â±3 mo after coronary revascularization. Results: On resting 99mTc.MlBl im ages, 302 segmentshad normal uptake, 183 segmentshad moderatelyreduceduptakeand 197 had severelyreducedup take. Of the segmentswith severelyreduceduptake,54 (27%) had increased uptake after nitroglycerineand were viable on 201fl images. Of the 143 (73%) segmentswith severely reduced @Â°Tc-MlBl uptakeand no changeafternitroglycerine, 81% werenonvi...","downloadable_attachments":[{"id":39742582,"asset_id":17848654,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37765334,"first_name":"Simone","last_name":"Maurea","domain_name":"independent","page_name":"SimoneMaurea","display_name":"Simone Maurea","profile_url":"https://independent.academia.edu/SimoneMaurea?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":46824,"name":"Echocardiography","url":"https://www.academia.edu/Documents/in/Echocardiography?f_ri=10035","nofollow":true},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=10035","nofollow":true},{"id":167876,"name":"Myocardial Revascularization","url":"https://www.academia.edu/Documents/in/Myocardial_Revascularization?f_ri=10035","nofollow":true},{"id":198747,"name":"Left Ventricular Dysfunction","url":"https://www.academia.edu/Documents/in/Left_Ventricular_Dysfunction?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":398808,"name":"Coronary heart disease","url":"https://www.academia.edu/Documents/in/Coronary_heart_disease?f_ri=10035"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=10035"},{"id":618800,"name":"Coronary Circulation","url":"https://www.academia.edu/Documents/in/Coronary_Circulation?f_ri=10035"},{"id":1941399,"name":"Nitroglycerin","url":"https://www.academia.edu/Documents/in/Nitroglycerin?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_80167142" data-work_id="80167142" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" rel="nofollow" href="https://www.academia.edu/80167142/Extraneural_dissemination_of_cerebellar_medulloblastoma_detected_by_18F_FDG_PET_CT_a_case_report_of_a_rare_situation_article_in_slovak_">Extraneural dissemination of cerebellar medulloblastoma detected by 18F-FDG PET/CT – a case report of a rare situation (article in slovak)</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In patients with medulloblastoma, extraneural metastases are well-known but very rare phenomenon. Herein we report a case of 11-year-old boy with medulloblastoma in cerebellar vermis, with early dissemination in spinal canal, treated by... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_80167142" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In patients with medulloblastoma, extraneural metastases are well-known but very rare phenomenon. Herein we report a case of 11-year-old boy with medulloblastoma in cerebellar vermis, with early dissemination in spinal canal, treated by surgery, craniospinal irradiation and high-dose chemotherapy. Three months after completion of treatment, the recurrent disease was identified in frontal lobe. The patient underwent surgery and radiotherapy; second-line chemotherapy was planned. After completion of radiotherapy the mass in left neck area appeared. Histology from lymph node excision confirmed metastasis of immature embryonal tumor, most likely anaplastic variant of medulloblastoma, however neuroblastoma was considered as well. To restage the disease 18F-FDG PET/CT and 123I-MIBG scans were performed. While 123I-MIBG study was completely negative, 18F-FDG PET/CT showed extensive metastatic disease with multiple FDG avid lesions through bone marrow, in lymph nodes and paranasal sinuses. MRI plays a major role in initial staging, grading and prognostic evaluation of medulloblastoma. 18F-FDG PET/CT is not routinely performed in re-staging of medulloblastoma, however, it may be useful to identify distant metastatic spread.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/80167142" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="160397309" href="https://dfnsp.academia.edu/RobertChrenko">Robert Chrenko</a><script data-card-contents-for-user="160397309" type="text/json">{"id":160397309,"first_name":"Robert","last_name":"Chrenko","domain_name":"dfnsp","page_name":"RobertChrenko","display_name":"Robert Chrenko","profile_url":"https://dfnsp.academia.edu/RobertChrenko?f_ri=10035","photo":"https://0.academia-photos.com/160397309/81979504/70579345/s65_robert.chrenko.jpeg"}</script></span></span></li><li class="js-paper-rank-work_80167142 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="80167142"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 80167142, container: ".js-paper-rank-work_80167142", }); });</script></li><li class="js-percentile-work_80167142 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 80167142; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_80167142"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_80167142 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="80167142"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 80167142; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=80167142]").text(description); $(".js-view-count-work_80167142").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_80167142").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="80167142"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="1646" rel="nofollow" href="https://www.academia.edu/Documents/in/Diagnostic_Radiography">Diagnostic Radiography</a>, <script data-card-contents-for-ri="1646" type="text/json">{"id":1646,"name":"Diagnostic Radiography","url":"https://www.academia.edu/Documents/in/Diagnostic_Radiography?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="19354" rel="nofollow" href="https://www.academia.edu/Documents/in/Radiotherapy">Radiotherapy</a><script data-card-contents-for-ri="19354" type="text/json">{"id":19354,"name":"Radiotherapy","url":"https://www.academia.edu/Documents/in/Radiotherapy?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=80167142]'), work: {"id":80167142,"title":"Extraneural dissemination of cerebellar medulloblastoma detected by 18F-FDG PET/CT – a case report of a rare situation (article in slovak)","created_at":"2022-05-29T01:47:37.711-07:00","url":"https://www.academia.edu/80167142/Extraneural_dissemination_of_cerebellar_medulloblastoma_detected_by_18F_FDG_PET_CT_a_case_report_of_a_rare_situation_article_in_slovak_?f_ri=10035","dom_id":"work_80167142","summary":"In patients with medulloblastoma, extraneural metastases are well-known but very rare phenomenon. Herein we report a case of 11-year-old boy with medulloblastoma in cerebellar vermis, with early dissemination in spinal canal, treated by surgery, craniospinal irradiation and high-dose chemotherapy. Three months after completion of treatment, the recurrent disease was identified in frontal lobe. The patient underwent surgery and radiotherapy; second-line chemotherapy was planned. After completion of radiotherapy the mass in left neck area appeared. Histology from lymph node excision confirmed metastasis of immature embryonal tumor, most likely anaplastic variant of medulloblastoma, however neuroblastoma was considered as well. To restage the disease 18F-FDG PET/CT and 123I-MIBG scans were performed. While 123I-MIBG study was completely negative, 18F-FDG PET/CT showed extensive metastatic disease with multiple FDG avid lesions through bone marrow, in lymph nodes and paranasal sinuses. MRI plays a major role in initial staging, grading and prognostic evaluation of medulloblastoma. 18F-FDG PET/CT is not routinely performed in re-staging of medulloblastoma, however, it may be useful to identify distant metastatic spread.","downloadable_attachments":[],"ordered_authors":[{"id":160397309,"first_name":"Robert","last_name":"Chrenko","domain_name":"dfnsp","page_name":"RobertChrenko","display_name":"Robert Chrenko","profile_url":"https://dfnsp.academia.edu/RobertChrenko?f_ri=10035","photo":"https://0.academia-photos.com/160397309/81979504/70579345/s65_robert.chrenko.jpeg"}],"research_interests":[{"id":1646,"name":"Diagnostic Radiography","url":"https://www.academia.edu/Documents/in/Diagnostic_Radiography?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":19354,"name":"Radiotherapy","url":"https://www.academia.edu/Documents/in/Radiotherapy?f_ri=10035","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_37389668" data-work_id="37389668" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/37389668/Radiopharmaceutical_Quality_Assurance_Pilot_Study">Radiopharmaceutical Quality Assurance—Pilot Study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">College of American Pathologists completed a pilot study to evaluate radiopharmaceutical quality assurance techniques. Thirty participants receivedfivevialseach, three for radiochemicalpurity assessment and two for the determination of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_37389668" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">College of American Pathologists completed a pilot study to evaluate radiopharmaceutical quality assurance techniques. Thirty participants receivedfivevialseach, three for radiochemicalpurity assessment and two for the determination of particle size and number. The first three vials showed chemical components that would produce >95% ofTc-99m Sn DTPA, @TcO4, or reduced hydrolyzed Tc-99m upon the addition of pertechnetate. The par</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/37389668" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="097f426e380194b4dc5d9f3bf0ab3cdd" rel="nofollow" data-download="{"attachment_id":57352865,"asset_id":37389668,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/57352865/download_file?st=MTc0MDU3MDk0OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51231238" href="https://independent.academia.edu/WilliamEckelman">William Eckelman</a><script data-card-contents-for-user="51231238" type="text/json">{"id":51231238,"first_name":"William","last_name":"Eckelman","domain_name":"independent","page_name":"WilliamEckelman","display_name":"William Eckelman","profile_url":"https://independent.academia.edu/WilliamEckelman?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_37389668 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="37389668"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 37389668, container: ".js-paper-rank-work_37389668", }); });</script></li><li class="js-percentile-work_37389668 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 37389668; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_37389668"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_37389668 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="37389668"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 37389668; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=37389668]").text(description); $(".js-view-count-work_37389668").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_37389668").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="37389668"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">4</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37306" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_Control">Quality Control</a>, <script data-card-contents-for-ri="37306" type="text/json">{"id":37306,"name":"Quality Control","url":"https://www.academia.edu/Documents/in/Quality_Control?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a>, <script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="967378" rel="nofollow" href="https://www.academia.edu/Documents/in/Radioisotopes">Radioisotopes</a><script data-card-contents-for-ri="967378" type="text/json">{"id":967378,"name":"Radioisotopes","url":"https://www.academia.edu/Documents/in/Radioisotopes?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=37389668]'), work: {"id":37389668,"title":"Radiopharmaceutical Quality Assurance—Pilot Study","created_at":"2018-09-12T04:50:38.360-07:00","url":"https://www.academia.edu/37389668/Radiopharmaceutical_Quality_Assurance_Pilot_Study?f_ri=10035","dom_id":"work_37389668","summary":"College of American Pathologists completed a pilot study to evaluate radiopharmaceutical quality assurance techniques. Thirty participants receivedfivevialseach, three for radiochemicalpurity assessment and two for the determination of particle size and number. The first three vials showed chemical components that would produce \u003e95% ofTc-99m Sn DTPA, @TcO4, or reduced hydrolyzed Tc-99m upon the addition of pertechnetate. The par","downloadable_attachments":[{"id":57352865,"asset_id":37389668,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51231238,"first_name":"William","last_name":"Eckelman","domain_name":"independent","page_name":"WilliamEckelman","display_name":"William Eckelman","profile_url":"https://independent.academia.edu/WilliamEckelman?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":37306,"name":"Quality Control","url":"https://www.academia.edu/Documents/in/Quality_Control?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":967378,"name":"Radioisotopes","url":"https://www.academia.edu/Documents/in/Radioisotopes?f_ri=10035","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_27166819" data-work_id="27166819" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/27166819/MR_imaging_in_the_triage_of_pregnant_patients_with_acute_abdominal_and_pelvic_pain">MR imaging in the triage of pregnant patients with acute abdominal and pelvic pain</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: To retrospectively assess the performance of MR imaging in the evaluation and triage of pregnant patients presenting with acute abdominal or pelvic pain. Method and materials: MRI studies of pregnant patients who were referred... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_27166819" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: To retrospectively assess the performance of MR imaging in the evaluation and triage of pregnant patients presenting with acute abdominal or pelvic pain. Method and materials: MRI studies of pregnant patients who were referred for acute abdominal pain between 2001 and 2007 were included. MR images were retrospectively reviewed and compared with surgical and pathologic findings and clinical follow-up data. Analysis of imaging findings included evaluation of the visceral organs, bowel and mesentery, appendix (for presence of appendicitis), ovaries (detection and adnexal masses were evaluated), focal inflammation, presence of abscesses, and any other abnormal findings. Results: A total of 118 pregnant patients were included. MR findings were inconclusive in 2 patients and were positive for acute appendicitis in 11 patients (n = 9 confirmed by surgery, n = 2 improved without surgery). One patient with inconclusive MR had surgically confirmed appendicitis; the other patient with inconclusive MR had surgically confirmed adnexal torsion. Other surgical/interventional diagnoses suggested by MR imaging were adnexal torsion (n = 4), abscess (n = 4), acute cholecystitis (n = 1), and gastric volvulus (n = 1). Two patients with MR diagnosis of torsion improved without surgery. One patient with MR diagnosis of abscess had biliary cystadenoma at surgery. The rest of the MR diagnoses above were confirmed surgically or interventionally. MR imaging was normal in 67 patients and demonstrated medically treatable etiology in 28 patients: adnexal lesions (n = 9), urinary pathology (n = 6), cholelithiasis (n = 4), degenerating fibroid (n = 3), DVT (n = 2), hernia (n = 1), colitis (n = 1), thick terminal ileum (n = 1), rectus hematoma (n = 1). Three of these patients had negative surgical exploration and one had adnexal mass excision during pregnancy. Other patients were discharged with medical treatment. The sensitivity, specificity, accuracy, positive predictive values (ppv), and negative predictive values (npv) of MR imaging for acute appendicitis, and surgical/ interventional diagnoses were 90.0% vs. 88.9%, 98.1% vs. 95.0%, 97.5% vs. 94.1%, 81.8% vs. 76.2%, 99.1% vs. 97.9%, respectively. Conclusion: MR imaging is an excellent modality for diagnosis of acute appendicitis and exclusion of diseases requiring surgical/interventional treatment. Therefore MR imaging is useful for triage of pregnant patients with acute abdominal and pelvic pain.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/27166819" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="1675a437678d6bb6a109dc28bfc72548" rel="nofollow" data-download="{"attachment_id":47414673,"asset_id":27166819,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47414673/download_file?st=MTc0MDU3MDk0OCw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="51234653" href="https://independent.academia.edu/RandyErnst">Randy Ernst</a><script data-card-contents-for-user="51234653" type="text/json">{"id":51234653,"first_name":"Randy","last_name":"Ernst","domain_name":"independent","page_name":"RandyErnst","display_name":"Randy Ernst","profile_url":"https://independent.academia.edu/RandyErnst?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_27166819 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="27166819"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 27166819, container: ".js-paper-rank-work_27166819", }); });</script></li><li class="js-percentile-work_27166819 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 27166819; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_27166819"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_27166819 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="27166819"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 27166819; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=27166819]").text(description); $(".js-view-count-work_27166819").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_27166819").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="27166819"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">22</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="3274" rel="nofollow" href="https://www.academia.edu/Documents/in/Gastroenterology">Gastroenterology</a>, <script data-card-contents-for-ri="3274" type="text/json">{"id":3274,"name":"Gastroenterology","url":"https://www.academia.edu/Documents/in/Gastroenterology?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4205" rel="nofollow" href="https://www.academia.edu/Documents/in/Data_Analysis">Data Analysis</a>, <script data-card-contents-for-ri="4205" type="text/json">{"id":4205,"name":"Data Analysis","url":"https://www.academia.edu/Documents/in/Data_Analysis?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a><script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=27166819]'), work: {"id":27166819,"title":"MR imaging in the triage of pregnant patients with acute abdominal and pelvic pain","created_at":"2016-07-21T16:35:38.002-07:00","url":"https://www.academia.edu/27166819/MR_imaging_in_the_triage_of_pregnant_patients_with_acute_abdominal_and_pelvic_pain?f_ri=10035","dom_id":"work_27166819","summary":"Purpose: To retrospectively assess the performance of MR imaging in the evaluation and triage of pregnant patients presenting with acute abdominal or pelvic pain. Method and materials: MRI studies of pregnant patients who were referred for acute abdominal pain between 2001 and 2007 were included. MR images were retrospectively reviewed and compared with surgical and pathologic findings and clinical follow-up data. Analysis of imaging findings included evaluation of the visceral organs, bowel and mesentery, appendix (for presence of appendicitis), ovaries (detection and adnexal masses were evaluated), focal inflammation, presence of abscesses, and any other abnormal findings. Results: A total of 118 pregnant patients were included. MR findings were inconclusive in 2 patients and were positive for acute appendicitis in 11 patients (n = 9 confirmed by surgery, n = 2 improved without surgery). One patient with inconclusive MR had surgically confirmed appendicitis; the other patient with inconclusive MR had surgically confirmed adnexal torsion. Other surgical/interventional diagnoses suggested by MR imaging were adnexal torsion (n = 4), abscess (n = 4), acute cholecystitis (n = 1), and gastric volvulus (n = 1). Two patients with MR diagnosis of torsion improved without surgery. One patient with MR diagnosis of abscess had biliary cystadenoma at surgery. The rest of the MR diagnoses above were confirmed surgically or interventionally. MR imaging was normal in 67 patients and demonstrated medically treatable etiology in 28 patients: adnexal lesions (n = 9), urinary pathology (n = 6), cholelithiasis (n = 4), degenerating fibroid (n = 3), DVT (n = 2), hernia (n = 1), colitis (n = 1), thick terminal ileum (n = 1), rectus hematoma (n = 1). Three of these patients had negative surgical exploration and one had adnexal mass excision during pregnancy. Other patients were discharged with medical treatment. The sensitivity, specificity, accuracy, positive predictive values (ppv), and negative predictive values (npv) of MR imaging for acute appendicitis, and surgical/ interventional diagnoses were 90.0% vs. 88.9%, 98.1% vs. 95.0%, 97.5% vs. 94.1%, 81.8% vs. 76.2%, 99.1% vs. 97.9%, respectively. Conclusion: MR imaging is an excellent modality for diagnosis of acute appendicitis and exclusion of diseases requiring surgical/interventional treatment. Therefore MR imaging is useful for triage of pregnant patients with acute abdominal and pelvic pain.","downloadable_attachments":[{"id":47414673,"asset_id":27166819,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":51234653,"first_name":"Randy","last_name":"Ernst","domain_name":"independent","page_name":"RandyErnst","display_name":"Randy Ernst","profile_url":"https://independent.academia.edu/RandyErnst?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3274,"name":"Gastroenterology","url":"https://www.academia.edu/Documents/in/Gastroenterology?f_ri=10035","nofollow":true},{"id":4205,"name":"Data Analysis","url":"https://www.academia.edu/Documents/in/Data_Analysis?f_ri=10035","nofollow":true},{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=10035"},{"id":37862,"name":"Abdominal Imaging","url":"https://www.academia.edu/Documents/in/Abdominal_Imaging?f_ri=10035"},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=10035"},{"id":69956,"name":"Triage","url":"https://www.academia.edu/Documents/in/Triage?f_ri=10035"},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":436755,"name":"Degeneration","url":"https://www.academia.edu/Documents/in/Degeneration?f_ri=10035"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=10035"},{"id":613632,"name":"Pelvic Pain","url":"https://www.academia.edu/Documents/in/Pelvic_Pain?f_ri=10035"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=10035"},{"id":987472,"name":"Gestation","url":"https://www.academia.edu/Documents/in/Gestation?f_ri=10035"},{"id":1024379,"name":"Nuclear Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Nuclear_Magnetic_Resonance_Imaging?f_ri=10035"},{"id":1122411,"name":"Mr Imaging","url":"https://www.academia.edu/Documents/in/Mr_Imaging?f_ri=10035"},{"id":1180715,"name":"Abdominal Pain","url":"https://www.academia.edu/Documents/in/Abdominal_Pain?f_ri=10035"},{"id":1259531,"name":"Acute Appendicitis","url":"https://www.academia.edu/Documents/in/Acute_Appendicitis?f_ri=10035"},{"id":1318938,"name":"Positive predictive value","url":"https://www.academia.edu/Documents/in/Positive_predictive_value?f_ri=10035"},{"id":1477805,"name":"Acute Abdomen","url":"https://www.academia.edu/Documents/in/Acute_Abdomen?f_ri=10035"},{"id":1881146,"name":"Medical Treatment","url":"https://www.academia.edu/Documents/in/Medical_Treatment?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20632281" data-work_id="20632281" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20632281/Damage_induced_by_stannous_chloride_in_plasmid_DNA">Damage induced by stannous chloride in plasmid DNA</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Stannous chloride (SnCl 2 ) is widely used in daily human life, for example, to conserve soft drinks, in food manufacturing and biocidal preparations. In nuclear medicine, stannous chloride is used as a reducing agent of Technetium-99m, a... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_20632281" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Stannous chloride (SnCl 2 ) is widely used in daily human life, for example, to conserve soft drinks, in food manufacturing and biocidal preparations. In nuclear medicine, stannous chloride is used as a reducing agent of Technetium-99m, a radionuclide used to label different cells and molecules. In spite of this, stannous chloride is able to generate reactive oxygen species (ROS) which can damage DNA. In this work, plasmid DNA (pUC 9.1) was incubated with SnCl 2 under different conditions and the results analyzed through DNA migration in agarose gel electrophoresis. Our data reinforce the powerful damaging effect induced by stannous ion and suggest that this salt can play a direct role in inducing DNA lesions.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20632281" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="db4892aa8a046c1112f3534e1a4314c7" rel="nofollow" data-download="{"attachment_id":41475908,"asset_id":20632281,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41475908/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="3504716" href="https://ufrj.academia.edu/ClaudiaLAGE">Claudia LAGE</a><script data-card-contents-for-user="3504716" type="text/json">{"id":3504716,"first_name":"Claudia","last_name":"LAGE","domain_name":"ufrj","page_name":"ClaudiaLAGE","display_name":"Claudia LAGE","profile_url":"https://ufrj.academia.edu/ClaudiaLAGE?f_ri=10035","photo":"https://0.academia-photos.com/3504716/3144088/3701651/s65_claudia.lage.jpg"}</script></span></span></li><li class="js-paper-rank-work_20632281 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="20632281"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 20632281, container: ".js-paper-rank-work_20632281", }); 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$(".js-view-count[data-work-id=20632281]").text(description); $(".js-view-count-work_20632281").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_20632281").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="20632281"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23066" rel="nofollow" href="https://www.academia.edu/Documents/in/DNA_damage">DNA damage</a>, <script data-card-contents-for-ri="23066" type="text/json">{"id":23066,"name":"DNA damage","url":"https://www.academia.edu/Documents/in/DNA_damage?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="48057" rel="nofollow" href="https://www.academia.edu/Documents/in/DNA">DNA</a>, <script data-card-contents-for-ri="48057" type="text/json">{"id":48057,"name":"DNA","url":"https://www.academia.edu/Documents/in/DNA?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="129749" rel="nofollow" href="https://www.academia.edu/Documents/in/Soft_Drinks">Soft Drinks</a><script data-card-contents-for-ri="129749" type="text/json">{"id":129749,"name":"Soft Drinks","url":"https://www.academia.edu/Documents/in/Soft_Drinks?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=20632281]'), work: {"id":20632281,"title":"Damage induced by stannous chloride in plasmid DNA","created_at":"2016-01-23T07:07:50.598-08:00","url":"https://www.academia.edu/20632281/Damage_induced_by_stannous_chloride_in_plasmid_DNA?f_ri=10035","dom_id":"work_20632281","summary":"Stannous chloride (SnCl 2 ) is widely used in daily human life, for example, to conserve soft drinks, in food manufacturing and biocidal preparations. In nuclear medicine, stannous chloride is used as a reducing agent of Technetium-99m, a radionuclide used to label different cells and molecules. In spite of this, stannous chloride is able to generate reactive oxygen species (ROS) which can damage DNA. In this work, plasmid DNA (pUC 9.1) was incubated with SnCl 2 under different conditions and the results analyzed through DNA migration in agarose gel electrophoresis. Our data reinforce the powerful damaging effect induced by stannous ion and suggest that this salt can play a direct role in inducing DNA lesions.","downloadable_attachments":[{"id":41475908,"asset_id":20632281,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":3504716,"first_name":"Claudia","last_name":"LAGE","domain_name":"ufrj","page_name":"ClaudiaLAGE","display_name":"Claudia LAGE","profile_url":"https://ufrj.academia.edu/ClaudiaLAGE?f_ri=10035","photo":"https://0.academia-photos.com/3504716/3144088/3701651/s65_claudia.lage.jpg"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":23066,"name":"DNA damage","url":"https://www.academia.edu/Documents/in/DNA_damage?f_ri=10035","nofollow":true},{"id":48057,"name":"DNA","url":"https://www.academia.edu/Documents/in/DNA?f_ri=10035","nofollow":true},{"id":129749,"name":"Soft Drinks","url":"https://www.academia.edu/Documents/in/Soft_Drinks?f_ri=10035","nofollow":true},{"id":190363,"name":"Plasmids","url":"https://www.academia.edu/Documents/in/Plasmids?f_ri=10035"},{"id":759403,"name":"Gel electrophoresis","url":"https://www.academia.edu/Documents/in/Gel_electrophoresis?f_ri=10035"},{"id":1320136,"name":"Plasmid DNA","url":"https://www.academia.edu/Documents/in/Plasmid_DNA?f_ri=10035"},{"id":1362652,"name":"Nucleic Acid Conformation","url":"https://www.academia.edu/Documents/in/Nucleic_Acid_Conformation?f_ri=10035"},{"id":1957240,"name":"ENVIRONMENTAL SCIENCE AND MANAGEMENT","url":"https://www.academia.edu/Documents/in/ENVIRONMENTAL_SCIENCE_AND_MANAGEMENT?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_76843694" data-work_id="76843694" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/76843694/Glypican_3_targeted_thorium_227_alpha_therapy_reduces_tumor_burden_in_an_orthotopic_xenograft_murine_model_of_hepatocellular_carcinoma">Glypican-3 targeted thorium-227 alpha therapy reduces tumor burden in an orthotopic xenograft murine model of hepatocellular carcinoma</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/76843694" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b0b234901e803b9f50e9147c8d6efacf" rel="nofollow" data-download="{"attachment_id":84416674,"asset_id":76843694,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/84416674/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="6983086" href="https://washington.academia.edu/DScottWilbur">D Scott Wilbur</a><script data-card-contents-for-user="6983086" type="text/json">{"id":6983086,"first_name":"D Scott","last_name":"Wilbur","domain_name":"washington","page_name":"DScottWilbur","display_name":"D Scott Wilbur","profile_url":"https://washington.academia.edu/DScottWilbur?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_76843694 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="76843694"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 76843694, container: ".js-paper-rank-work_76843694", }); 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$(".js-view-count[data-work-id=76843694]").text(description); $(".js-view-count-work_76843694").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_76843694").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="76843694"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=76843694]'), work: {"id":76843694,"title":"Glypican-3 targeted thorium-227 alpha therapy reduces tumor burden in an orthotopic xenograft murine model of hepatocellular carcinoma","created_at":"2022-04-18T09:23:04.492-07:00","url":"https://www.academia.edu/76843694/Glypican_3_targeted_thorium_227_alpha_therapy_reduces_tumor_burden_in_an_orthotopic_xenograft_murine_model_of_hepatocellular_carcinoma?f_ri=10035","dom_id":"work_76843694","summary":null,"downloadable_attachments":[{"id":84416674,"asset_id":76843694,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":6983086,"first_name":"D Scott","last_name":"Wilbur","domain_name":"washington","page_name":"DScottWilbur","display_name":"D Scott Wilbur","profile_url":"https://washington.academia.edu/DScottWilbur?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_76692869" data-work_id="76692869" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/76692869/Nuclear_medicine_in_primary_bone_tumors">Nuclear medicine in primary bone tumors</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Introduction: Conventional radiography is the method of choice to diagnose a primary bone tumor but in many cases it is necessary to integrate it with nuclear medicine scintigraphy using several radionuclides, including 67 Ga, 201 Tl, 99m... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_76692869" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Introduction: Conventional radiography is the method of choice to diagnose a primary bone tumor but in many cases it is necessary to integrate it with nuclear medicine scintigraphy using several radionuclides, including 67 Ga, 201 Tl, 99m Tc-MIBI and especially 99m Tc-diphosphonates. Recently a new technique has been recently introduced, that is positron emission tomography with 2(18 F) fluoro-2 deoxy-D-glucose as radiopharmaceutical. Objective: The specific purpose of this work is to show that nuclear medicine bone scanning is a very important method in the detection and diagnostic management of primary bone tumors. Diagnosis, staging and follow-up: Three-phase bone scintigraphy, integrated with SPECT, is clinically useful to confirm the radiologic diagnosis of bone tumor. These techniques conveniently related to each other and to radiographic findings, can evaluate the tumor's local aggressiveness, often differentiating benign from malignant lesions, to monitor treatment efficacy, to permit total body scanning for the detection of recurrences. Nuclear medicine diagnostic techniques are not in competition with radiographic tools as CT and MRI which are highly sensitive in detecting even small lesions thanks to their excellent anatomical resolution. In questionable cases, we can integrate radiologic imaging with dynamic studies, in particular with FDG-PET, increasing the specificity of diagnosis and permitting more accurate follow-up. Conclusions: Patient management optimization needs the integration between dynamic nuclear medicine findings and the anatomical patterns provided by conventional radiology to increase imaging sensitivity and specificity. Equipe work is determinant to customize the diagnostic work-up to the individual patient's needs to reduce the cost of patient management avoiding useless examinations.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/76692869" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fda127d04bd7898e9398272a7dc9c015" rel="nofollow" data-download="{"attachment_id":84315612,"asset_id":76692869,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/84315612/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="214976582" href="https://independent.academia.edu/RossellaLattanzi">Rossella Lattanzi</a><script data-card-contents-for-user="214976582" type="text/json">{"id":214976582,"first_name":"Rossella","last_name":"Lattanzi","domain_name":"independent","page_name":"RossellaLattanzi","display_name":"Rossella Lattanzi","profile_url":"https://independent.academia.edu/RossellaLattanzi?f_ri=10035","photo":"https://0.academia-photos.com/214976582/73598666/62082406/s65_rossella.lattanzi.png"}</script></span></span></li><li class="js-paper-rank-work_76692869 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="76692869"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 76692869, container: ".js-paper-rank-work_76692869", }); });</script></li><li class="js-percentile-work_76692869 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 76692869; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_76692869"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_76692869 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="76692869"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 76692869; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=76692869]").text(description); $(".js-view-count-work_76692869").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_76692869").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="76692869"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="137516" rel="nofollow" href="https://www.academia.edu/Documents/in/Follow-up_studies">Follow-up studies</a>, <script data-card-contents-for-ri="137516" type="text/json">{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="162159" rel="nofollow" href="https://www.academia.edu/Documents/in/Differential_Diagnosis">Differential Diagnosis</a><script data-card-contents-for-ri="162159" type="text/json">{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=76692869]'), work: {"id":76692869,"title":"Nuclear medicine in primary bone tumors","created_at":"2022-04-17T03:25:03.374-07:00","url":"https://www.academia.edu/76692869/Nuclear_medicine_in_primary_bone_tumors?f_ri=10035","dom_id":"work_76692869","summary":"Introduction: Conventional radiography is the method of choice to diagnose a primary bone tumor but in many cases it is necessary to integrate it with nuclear medicine scintigraphy using several radionuclides, including 67 Ga, 201 Tl, 99m Tc-MIBI and especially 99m Tc-diphosphonates. Recently a new technique has been recently introduced, that is positron emission tomography with 2(18 F) fluoro-2 deoxy-D-glucose as radiopharmaceutical. Objective: The specific purpose of this work is to show that nuclear medicine bone scanning is a very important method in the detection and diagnostic management of primary bone tumors. Diagnosis, staging and follow-up: Three-phase bone scintigraphy, integrated with SPECT, is clinically useful to confirm the radiologic diagnosis of bone tumor. These techniques conveniently related to each other and to radiographic findings, can evaluate the tumor's local aggressiveness, often differentiating benign from malignant lesions, to monitor treatment efficacy, to permit total body scanning for the detection of recurrences. Nuclear medicine diagnostic techniques are not in competition with radiographic tools as CT and MRI which are highly sensitive in detecting even small lesions thanks to their excellent anatomical resolution. In questionable cases, we can integrate radiologic imaging with dynamic studies, in particular with FDG-PET, increasing the specificity of diagnosis and permitting more accurate follow-up. Conclusions: Patient management optimization needs the integration between dynamic nuclear medicine findings and the anatomical patterns provided by conventional radiology to increase imaging sensitivity and specificity. Equipe work is determinant to customize the diagnostic work-up to the individual patient's needs to reduce the cost of patient management avoiding useless examinations.","downloadable_attachments":[{"id":84315612,"asset_id":76692869,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":214976582,"first_name":"Rossella","last_name":"Lattanzi","domain_name":"independent","page_name":"RossellaLattanzi","display_name":"Rossella Lattanzi","profile_url":"https://independent.academia.edu/RossellaLattanzi?f_ri=10035","photo":"https://0.academia-photos.com/214976582/73598666/62082406/s65_rossella.lattanzi.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=10035","nofollow":true},{"id":162159,"name":"Differential Diagnosis","url":"https://www.academia.edu/Documents/in/Differential_Diagnosis?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=10035"},{"id":1256683,"name":"Bone and Bones","url":"https://www.academia.edu/Documents/in/Bone_and_Bones?f_ri=10035"},{"id":3118074,"name":"Neoplasm staging","url":"https://www.academia.edu/Documents/in/Neoplasm_staging?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_72840692" data-work_id="72840692" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/72840692/Maternal_fetal_in_vivo_imaging_a_combined_PET_and_MRI_study">Maternal-fetal in vivo imaging: a combined PET and MRI study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">An understanding of how drugs are transferred between mother and fetus during the gestational period is an important medical issue of relevance to both therapeutic drugs and drugs of abuse. Though there are several in vitro and in vivo... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72840692" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">An understanding of how drugs are transferred between mother and fetus during the gestational period is an important medical issue of relevance to both therapeutic drugs and drugs of abuse. Though there are several in vitro and in vivo methods to examine this issue, all have limitations. Furthermore, ethical and safety considerations generally preclude such studies in pregnant humans. PET and appropriately labeled compounds have the ability to provide information on both maternal-fetal drug pharmacokinetics and pharmacodynamics. We present here a nonhuman primate animal model and the methodology for combining PET and MRI to identify fetal organs and to measure maternal and fetal isotope distribution using (18)F-FDG and a whole-body imaging protocol to demonstrate proof-of-principle.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72840692" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ad57bd2ae28e024de6514fae617b488f" rel="nofollow" data-download="{"attachment_id":81605428,"asset_id":72840692,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81605428/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39346729" href="https://independent.academia.edu/DavidSchlyer">David Schlyer</a><script data-card-contents-for-user="39346729" type="text/json">{"id":39346729,"first_name":"David","last_name":"Schlyer","domain_name":"independent","page_name":"DavidSchlyer","display_name":"David Schlyer","profile_url":"https://independent.academia.edu/DavidSchlyer?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_72840692 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72840692"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72840692, container: ".js-paper-rank-work_72840692", }); });</script></li><li class="js-percentile-work_72840692 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 72840692; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_72840692"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_72840692 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="72840692"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 72840692; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=72840692]").text(description); $(".js-view-count-work_72840692").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_72840692").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="72840692"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44507" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear">Nuclear</a><script data-card-contents-for-ri="44507" type="text/json">{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72840692]'), work: {"id":72840692,"title":"Maternal-fetal in vivo imaging: a combined PET and MRI study","created_at":"2022-03-02T15:35:25.174-08:00","url":"https://www.academia.edu/72840692/Maternal_fetal_in_vivo_imaging_a_combined_PET_and_MRI_study?f_ri=10035","dom_id":"work_72840692","summary":"An understanding of how drugs are transferred between mother and fetus during the gestational period is an important medical issue of relevance to both therapeutic drugs and drugs of abuse. Though there are several in vitro and in vivo methods to examine this issue, all have limitations. Furthermore, ethical and safety considerations generally preclude such studies in pregnant humans. PET and appropriately labeled compounds have the ability to provide information on both maternal-fetal drug pharmacokinetics and pharmacodynamics. We present here a nonhuman primate animal model and the methodology for combining PET and MRI to identify fetal organs and to measure maternal and fetal isotope distribution using (18)F-FDG and a whole-body imaging protocol to demonstrate proof-of-principle.","downloadable_attachments":[{"id":81605428,"asset_id":72840692,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39346729,"first_name":"David","last_name":"Schlyer","domain_name":"independent","page_name":"DavidSchlyer","display_name":"David Schlyer","profile_url":"https://independent.academia.edu/DavidSchlyer?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true},{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035","nofollow":true},{"id":62550,"name":"Pregnancy","url":"https://www.academia.edu/Documents/in/Pregnancy?f_ri=10035"},{"id":76061,"name":"Placenta","url":"https://www.academia.edu/Documents/in/Placenta?f_ri=10035"},{"id":96379,"name":"PET imaging","url":"https://www.academia.edu/Documents/in/PET_imaging?f_ri=10035"},{"id":100540,"name":"Feasibility Studies","url":"https://www.academia.edu/Documents/in/Feasibility_Studies?f_ri=10035"},{"id":123287,"name":"Three Dimensional Imaging","url":"https://www.academia.edu/Documents/in/Three_Dimensional_Imaging?f_ri=10035"},{"id":151951,"name":"Animal Model","url":"https://www.academia.edu/Documents/in/Animal_Model?f_ri=10035"},{"id":189685,"name":"In Vivo Imaging","url":"https://www.academia.edu/Documents/in/In_Vivo_Imaging?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":254060,"name":"General Anesthesia","url":"https://www.academia.edu/Documents/in/General_Anesthesia?f_ri=10035"},{"id":600780,"name":"Drugs of Abuse","url":"https://www.academia.edu/Documents/in/Drugs_of_Abuse?f_ri=10035"},{"id":770944,"name":"Fetus","url":"https://www.academia.edu/Documents/in/Fetus?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"},{"id":1122411,"name":"Mr Imaging","url":"https://www.academia.edu/Documents/in/Mr_Imaging?f_ri=10035"},{"id":2950651,"name":"Tissue distribution","url":"https://www.academia.edu/Documents/in/Tissue_distribution?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_72348165" data-work_id="72348165" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/72348165/Cerebral_perfusion_scanning_in_treating_AIDS_dementia_A_pilot_study">Cerebral perfusion scanning in treating AIDS dementia: A pilot study</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) is a common effect of the AIDS virus. We studied the regional cerebral blood flow of patients with early ADC and its response to atevirdine mesylate. Methods: Ten men with... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_72348165" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) is a common effect of the AIDS virus. We studied the regional cerebral blood flow of patients with early ADC and its response to atevirdine mesylate. Methods: Ten men with early ADC, who had failed or were intolerant to zidovudine or didanosine therapy, were treated with atevirdine mesylate for 12 wk. Cerebral perfusion SPECT using 99mTc-HMPAO was performed at Week 0 and Week 12. SPECT images were analyzed qualitatively and semiquantitatively. Results: The cerebral perfusion abnormalities in early ADC were usually mild and characteristically involved the cortices and periventricular regions bilaterally and symmetrically. Four patients were able to complete the protocol. Three of these patients re sponded to atevirdine clinically, two of whom showed improvement in their Week 12 SPECT images. The other responder had an essentially unchanged image. The patient who did not respond to atevirdine showed a definite deterioration in cerebral perfusion. Conclusion: Cerebral perfusion SPECT is useful in detecting and assessing therapeutic responses in ADC. The preliminary results of atevirdine in treating ADC are promising and need further investiga tion.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/72348165" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="cd8aa7dd0e11b58a9bc8b443582505df" rel="nofollow" data-download="{"attachment_id":81309672,"asset_id":72348165,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/81309672/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36307415" href="https://independent.academia.edu/JudithFreund">Judith Freund</a><script data-card-contents-for-user="36307415" type="text/json">{"id":36307415,"first_name":"Judith","last_name":"Freund","domain_name":"independent","page_name":"JudithFreund","display_name":"Judith Freund","profile_url":"https://independent.academia.edu/JudithFreund?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_72348165 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="72348165"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 72348165, container: ".js-paper-rank-work_72348165", }); });</script></li><li class="js-percentile-work_72348165 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 72348165; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_72348165"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_72348165 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="72348165"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 72348165; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=72348165]").text(description); $(".js-view-count-work_72348165").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_72348165").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="72348165"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="61474" rel="nofollow" href="https://www.academia.edu/Documents/in/Brain">Brain</a>, <script data-card-contents-for-ri="61474" type="text/json">{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=72348165]'), work: {"id":72348165,"title":"Cerebral perfusion scanning in treating AIDS dementia: A pilot study","created_at":"2022-02-23T13:18:52.945-08:00","url":"https://www.academia.edu/72348165/Cerebral_perfusion_scanning_in_treating_AIDS_dementia_A_pilot_study?f_ri=10035","dom_id":"work_72348165","summary":"Acquired immunodeficiency syndrome (AIDS) dementia complex (ADC) is a common effect of the AIDS virus. We studied the regional cerebral blood flow of patients with early ADC and its response to atevirdine mesylate. Methods: Ten men with early ADC, who had failed or were intolerant to zidovudine or didanosine therapy, were treated with atevirdine mesylate for 12 wk. Cerebral perfusion SPECT using 99mTc-HMPAO was performed at Week 0 and Week 12. SPECT images were analyzed qualitatively and semiquantitatively. Results: The cerebral perfusion abnormalities in early ADC were usually mild and characteristically involved the cortices and periventricular regions bilaterally and symmetrically. Four patients were able to complete the protocol. Three of these patients re sponded to atevirdine clinically, two of whom showed improvement in their Week 12 SPECT images. The other responder had an essentially unchanged image. The patient who did not respond to atevirdine showed a definite deterioration in cerebral perfusion. Conclusion: Cerebral perfusion SPECT is useful in detecting and assessing therapeutic responses in ADC. The preliminary results of atevirdine in treating ADC are promising and need further investiga tion.","downloadable_attachments":[{"id":81309672,"asset_id":72348165,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36307415,"first_name":"Judith","last_name":"Freund","domain_name":"independent","page_name":"JudithFreund","display_name":"Judith Freund","profile_url":"https://independent.academia.edu/JudithFreund?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":308908,"name":"Pilot study","url":"https://www.academia.edu/Documents/in/Pilot_study?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":493004,"name":"Regional Cerebral Blood Flow","url":"https://www.academia.edu/Documents/in/Regional_Cerebral_Blood_Flow?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"},{"id":945595,"name":"Pilot Projects","url":"https://www.academia.edu/Documents/in/Pilot_Projects?f_ri=10035"},{"id":988873,"name":"AIDS Dementia Complex","url":"https://www.academia.edu/Documents/in/AIDS_Dementia_Complex?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_70422015" data-work_id="70422015" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/70422015/Evaluation_of_Image_Registration_in_PET_CT_of_the_Liver_and_Recommendations_for_Optimized_Imaging">Evaluation of Image Registration in PET/CT of the Liver and Recommendations for Optimized Imaging</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Multimodality PET/CT of the liver can be performed with an integrated (hybrid) PET/CT scanner or with software fusion of dedicated PET and CT. Accurate anatomic correlation and good image quality of both modalities are important... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_70422015" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Multimodality PET/CT of the liver can be performed with an integrated (hybrid) PET/CT scanner or with software fusion of dedicated PET and CT. Accurate anatomic correlation and good image quality of both modalities are important prerequisites, regardless of the applied method. Registration accuracy is influenced by breathing motion differences on PET and CT, which may also have impact on (attenuation correction-related) artifacts, especially in the upper abdomen. The impact of these issues was evaluated for both hybrid PET/CT and software fusion, focused on imaging of the liver. Methods: Thirty patients underwent hybrid PET/CT, 20 with CT during expiration breathhold (EB) and 10 with CT during free breathing (FB). Ten additional patients underwent software fusion of dedicated PET and dedicated expiration breath-hold CT (SF). The image registration accuracy was evaluated at the location of liver borders on CT and uncorrected PET images and at the location of liver lesions. Attenuation-correction artifacts were evaluated by comparison of liver borders on uncorrected and attenuationcorrected PET images. CT images were evaluated for the presence of breathing artifacts. Results: In EB, 40% of patients had an absolute registration error of the diaphragm in the craniocaudal direction of .1 cm (range, 216 to 44 mm), and 45% of lesions were mispositioned .1 cm. In 50% of cases, attenuationcorrection artifacts caused a deformation of the liver dome on PET of .1 cm. Poor compliance to breath-hold instructions caused CT artifacts in 55% of cases. In FB, 30% had registration errors of .1 cm (range, 24 to 16 mm) and PET artifacts were less extensive, but all CT images had breathing artifacts. As SF allows independent alignment of PET and CT, no registration errors or artifacts of .1 cm of the diaphragm occurred. Conclusion: Hybrid PET/CT of the liver may have significant registration errors and artifacts related to breathing motion. The extent of these issues depends on the selected breathing protocol and the speed of the CT scanner. No protocol or scanner can guarantee perfect image fusion. On the basis of these findings, recommendations were formulated with regard to scanner requirements, breathing protocols, and reporting.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/70422015" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4a3176aaac021139eb7e6a4547d834ae" rel="nofollow" data-download="{"attachment_id":80181838,"asset_id":70422015,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80181838/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44848739" href="https://independent.academia.edu/FCorstens">F. Corstens</a><script data-card-contents-for-user="44848739" type="text/json">{"id":44848739,"first_name":"F.","last_name":"Corstens","domain_name":"independent","page_name":"FCorstens","display_name":"F. Corstens","profile_url":"https://independent.academia.edu/FCorstens?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_70422015 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="70422015"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 70422015, container: ".js-paper-rank-work_70422015", }); });</script></li><li class="js-percentile-work_70422015 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 70422015; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_70422015"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_70422015 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="70422015"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 70422015; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=70422015]").text(description); $(".js-view-count-work_70422015").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_70422015").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="70422015"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="626" rel="nofollow" href="https://www.academia.edu/Documents/in/Oncology">Oncology</a>, <script data-card-contents-for-ri="626" type="text/json">{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23518" rel="nofollow" href="https://www.academia.edu/Documents/in/Positron_Emission_Tomography">Positron Emission Tomography</a>, <script data-card-contents-for-ri="23518" type="text/json">{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=70422015]'), work: {"id":70422015,"title":"Evaluation of Image Registration in PET/CT of the Liver and Recommendations for Optimized Imaging","created_at":"2022-02-04T06:12:47.869-08:00","url":"https://www.academia.edu/70422015/Evaluation_of_Image_Registration_in_PET_CT_of_the_Liver_and_Recommendations_for_Optimized_Imaging?f_ri=10035","dom_id":"work_70422015","summary":"Multimodality PET/CT of the liver can be performed with an integrated (hybrid) PET/CT scanner or with software fusion of dedicated PET and CT. Accurate anatomic correlation and good image quality of both modalities are important prerequisites, regardless of the applied method. Registration accuracy is influenced by breathing motion differences on PET and CT, which may also have impact on (attenuation correction-related) artifacts, especially in the upper abdomen. The impact of these issues was evaluated for both hybrid PET/CT and software fusion, focused on imaging of the liver. Methods: Thirty patients underwent hybrid PET/CT, 20 with CT during expiration breathhold (EB) and 10 with CT during free breathing (FB). Ten additional patients underwent software fusion of dedicated PET and dedicated expiration breath-hold CT (SF). The image registration accuracy was evaluated at the location of liver borders on CT and uncorrected PET images and at the location of liver lesions. Attenuation-correction artifacts were evaluated by comparison of liver borders on uncorrected and attenuationcorrected PET images. CT images were evaluated for the presence of breathing artifacts. Results: In EB, 40% of patients had an absolute registration error of the diaphragm in the craniocaudal direction of .1 cm (range, 216 to 44 mm), and 45% of lesions were mispositioned .1 cm. In 50% of cases, attenuationcorrection artifacts caused a deformation of the liver dome on PET of .1 cm. Poor compliance to breath-hold instructions caused CT artifacts in 55% of cases. In FB, 30% had registration errors of .1 cm (range, 24 to 16 mm) and PET artifacts were less extensive, but all CT images had breathing artifacts. As SF allows independent alignment of PET and CT, no registration errors or artifacts of .1 cm of the diaphragm occurred. Conclusion: Hybrid PET/CT of the liver may have significant registration errors and artifacts related to breathing motion. The extent of these issues depends on the selected breathing protocol and the speed of the CT scanner. No protocol or scanner can guarantee perfect image fusion. On the basis of these findings, recommendations were formulated with regard to scanner requirements, breathing protocols, and reporting.","downloadable_attachments":[{"id":80181838,"asset_id":70422015,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44848739,"first_name":"F.","last_name":"Corstens","domain_name":"independent","page_name":"FCorstens","display_name":"F. Corstens","profile_url":"https://independent.academia.edu/FCorstens?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true},{"id":29731,"name":"Image Registration","url":"https://www.academia.edu/Documents/in/Image_Registration?f_ri=10035"},{"id":29916,"name":"PET","url":"https://www.academia.edu/Documents/in/PET?f_ri=10035"},{"id":30415,"name":"Image Quality","url":"https://www.academia.edu/Documents/in/Image_Quality?f_ri=10035"},{"id":71437,"name":"Liver","url":"https://www.academia.edu/Documents/in/Liver?f_ri=10035"},{"id":83038,"name":"Image fusion","url":"https://www.academia.edu/Documents/in/Image_fusion?f_ri=10035"},{"id":93817,"name":"Attenuation Correction","url":"https://www.academia.edu/Documents/in/Attenuation_Correction?f_ri=10035"},{"id":96379,"name":"PET imaging","url":"https://www.academia.edu/Documents/in/PET_imaging?f_ri=10035"},{"id":172678,"name":"Artifacts","url":"https://www.academia.edu/Documents/in/Artifacts?f_ri=10035"},{"id":202428,"name":"Respiration","url":"https://www.academia.edu/Documents/in/Respiration?f_ri=10035"},{"id":220049,"name":"Accuracy","url":"https://www.academia.edu/Documents/in/Accuracy?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=10035"},{"id":3562342,"name":"Liver neoplasms","url":"https://www.academia.edu/Documents/in/Liver_neoplasms?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_33898065" data-work_id="33898065" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/33898065/Validation_of_lactose_13C_ureide_breath_test_for_determination_of_orocecal_transit_time_by_scintigraphy">Validation of lactose-[13C] ureide breath test for determination of orocecal transit time by scintigraphy</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/33898065" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="3429102d015d78958b5f063253c2ea89" rel="nofollow" data-download="{"attachment_id":53870892,"asset_id":33898065,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53870892/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="31408899" href="https://independent.academia.edu/BennyGeypens">Benny Geypens</a><script data-card-contents-for-user="31408899" type="text/json">{"id":31408899,"first_name":"Benny","last_name":"Geypens","domain_name":"independent","page_name":"BennyGeypens","display_name":"Benny Geypens","profile_url":"https://independent.academia.edu/BennyGeypens?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_33898065 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="33898065"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 33898065, container: ".js-paper-rank-work_33898065", }); });</script></li><li class="js-percentile-work_33898065 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33898065; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_33898065"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_33898065 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="33898065"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33898065; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33898065]").text(description); $(".js-view-count-work_33898065").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_33898065").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="33898065"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">8</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="5769" rel="nofollow" href="https://www.academia.edu/Documents/in/Mass_Spectrometry">Mass Spectrometry</a>, <script data-card-contents-for-ri="5769" type="text/json">{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="44507" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear">Nuclear</a>, <script data-card-contents-for-ri="44507" type="text/json">{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=33898065]'), work: {"id":33898065,"title":"Validation of lactose-[13C] ureide breath test for determination of orocecal transit time by scintigraphy","created_at":"2017-07-16T06:30:10.661-07:00","url":"https://www.academia.edu/33898065/Validation_of_lactose_13C_ureide_breath_test_for_determination_of_orocecal_transit_time_by_scintigraphy?f_ri=10035","dom_id":"work_33898065","summary":null,"downloadable_attachments":[{"id":53870892,"asset_id":33898065,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":31408899,"first_name":"Benny","last_name":"Geypens","domain_name":"independent","page_name":"BennyGeypens","display_name":"Benny Geypens","profile_url":"https://independent.academia.edu/BennyGeypens?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":5769,"name":"Mass Spectrometry","url":"https://www.academia.edu/Documents/in/Mass_Spectrometry?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":336223,"name":"Digestive System","url":"https://www.academia.edu/Documents/in/Digestive_System?f_ri=10035"},{"id":402186,"name":"Mouth","url":"https://www.academia.edu/Documents/in/Mouth?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"},{"id":1129054,"name":"Gastrointestinal Transit Time","url":"https://www.academia.edu/Documents/in/Gastrointestinal_Transit_Time?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13318564" data-work_id="13318564" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/13318564/Quantitative_analysis_of_CT_perfusion_parameters_in_the_evaluation_of_brain_gliomas_and_metastases">Quantitative analysis of CT-perfusion parameters in the evaluation of brain gliomas and metastases</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The paper reports a quantitative analysis of the perfusion maps of 22 patients, affected by gliomas or by metastasis, with the aim of characterizing the malignant tissue with respect to the normal tissue. The gold standard was obtained by... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13318564" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The paper reports a quantitative analysis of the perfusion maps of 22 patients, affected by gliomas or by metastasis, with the aim of characterizing the malignant tissue with respect to the normal tissue. The gold standard was obtained by histological exam or nuclear medicine techniques. The perfusion scan provided 11 parametric maps, including Cerebral Blood Volume (CBV), Cerebral Blood Flow (CBF), Average Perfusion (P mean ) and Permeability-surface area product (PS).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13318564" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d4020df3145ad5fa79afbc4ee535e8fb" rel="nofollow" data-download="{"attachment_id":45474606,"asset_id":13318564,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45474606/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32564152" href="https://independent.academia.edu/AnnaDiNallo">Anna Di Nallo</a><script data-card-contents-for-user="32564152" type="text/json">{"id":32564152,"first_name":"Anna Di","last_name":"Nallo","domain_name":"independent","page_name":"AnnaDiNallo","display_name":"Anna Di Nallo","profile_url":"https://independent.academia.edu/AnnaDiNallo?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_13318564 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13318564"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13318564, container: ".js-paper-rank-work_13318564", }); 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The gold standard was obtained by histological exam or nuclear medicine techniques. The perfusion scan provided 11 parametric maps, including Cerebral Blood Volume (CBV), Cerebral Blood Flow (CBF), Average Perfusion (P mean ) and Permeability-surface area product (PS).","downloadable_attachments":[{"id":45474606,"asset_id":13318564,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32564152,"first_name":"Anna Di","last_name":"Nallo","domain_name":"independent","page_name":"AnnaDiNallo","display_name":"Anna Di Nallo","profile_url":"https://independent.academia.edu/AnnaDiNallo?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":3243,"name":"Nonparametric Statistics","url":"https://www.academia.edu/Documents/in/Nonparametric_Statistics?f_ri=10035","nofollow":true},{"id":5187,"name":"Statistical Analysis","url":"https://www.academia.edu/Documents/in/Statistical_Analysis?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":37434,"name":"Quantitative analysis","url":"https://www.academia.edu/Documents/in/Quantitative_analysis?f_ri=10035","nofollow":true},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=10035"},{"id":69841,"name":"Standard Deviation","url":"https://www.academia.edu/Documents/in/Standard_Deviation?f_ri=10035"},{"id":76383,"name":"Glioma","url":"https://www.academia.edu/Documents/in/Glioma?f_ri=10035"},{"id":161534,"name":"Perfusion","url":"https://www.academia.edu/Documents/in/Perfusion?f_ri=10035"},{"id":172827,"name":"Brain Ischemia","url":"https://www.academia.edu/Documents/in/Brain_Ischemia?f_ri=10035"},{"id":194916,"name":"ROC Curve","url":"https://www.academia.edu/Documents/in/ROC_Curve?f_ri=10035"},{"id":209591,"name":"Ct Scan","url":"https://www.academia.edu/Documents/in/Ct_Scan?f_ri=10035"},{"id":313752,"name":"Gold Standard","url":"https://www.academia.edu/Documents/in/Gold_Standard?f_ri=10035"},{"id":329844,"name":"Experimental","url":"https://www.academia.edu/Documents/in/Experimental?f_ri=10035"},{"id":386356,"name":"Surface Area","url":"https://www.academia.edu/Documents/in/Surface_Area?f_ri=10035"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=10035"},{"id":641216,"name":"Quantitative Analysis","url":"https://www.academia.edu/Documents/in/Quantitative_Analysis-1?f_ri=10035"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=10035"},{"id":970066,"name":"Cerebral Blood Flow","url":"https://www.academia.edu/Documents/in/Cerebral_Blood_Flow?f_ri=10035"},{"id":1159970,"name":"Brain Neoplasm","url":"https://www.academia.edu/Documents/in/Brain_Neoplasm?f_ri=10035"},{"id":1309706,"name":"Area Under Curve","url":"https://www.academia.edu/Documents/in/Area_Under_Curve?f_ri=10035"},{"id":1372278,"name":"Region of Interest","url":"https://www.academia.edu/Documents/in/Region_of_Interest?f_ri=10035"},{"id":1407305,"name":"Contrast Media","url":"https://www.academia.edu/Documents/in/Contrast_Media?f_ri=10035"},{"id":1425045,"name":"Brain Neoplasms","url":"https://www.academia.edu/Documents/in/Brain_Neoplasms?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_14163037 coauthored" data-work_id="14163037" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/14163037/Characterization_of_Japanese_standards_for_myocardial_sympathetic_and_metabolic_imaging_in_comparison_with_perfusion_imaging">Characterization of Japanese standards for myocardial sympathetic and metabolic imaging in comparison with perfusion imaging</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective The standard patterns of myocardial radiotracer distribution of 123 I-metaiodobenzylguanidine (MIBG) and 123 I-b-methyl-p-iodophenyl-pentadecanoic acid (BMIPP) should be defined in a Japanese population. The purpose of this... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_14163037" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective The standard patterns of myocardial radiotracer distribution of 123 I-metaiodobenzylguanidine (MIBG) and 123 I-b-methyl-p-iodophenyl-pentadecanoic acid (BMIPP) should be defined in a Japanese population. The purpose of this study was to present and provide data on the characteristics of MIBG and BMIPP with respect to myocardial single photon emission computed tomography. Methods The normal database included 123 I-MIBG and 123 I-BMIPP imaging and a 99m Tc-sestamibi/tetrofosmin myocardial perfusion study. The projection images were transferred by digital imaging and communications in medicine (DICOM) format and reconstructed and analyzed with polar maps.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/14163037" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="fe85453e5667609ee8b635f4a3626ff8" rel="nofollow" data-download="{"attachment_id":44550730,"asset_id":14163037,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44550730/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33148106" href="https://kanazawa-u.academia.edu/KenichiNakajima">Kenichi Nakajima</a><script data-card-contents-for-user="33148106" type="text/json">{"id":33148106,"first_name":"Kenichi","last_name":"Nakajima","domain_name":"kanazawa-u","page_name":"KenichiNakajima","display_name":"Kenichi Nakajima","profile_url":"https://kanazawa-u.academia.edu/KenichiNakajima?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-14163037">+1</span><div class="hidden js-additional-users-14163037"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://independent.academia.edu/KoichiOkuda">Koichi Okuda</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-14163037'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-14163037').html(); 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The purpose of this study was to present and provide data on the characteristics of MIBG and BMIPP with respect to myocardial single photon emission computed tomography. Methods The normal database included 123 I-MIBG and 123 I-BMIPP imaging and a 99m Tc-sestamibi/tetrofosmin myocardial perfusion study. The projection images were transferred by digital imaging and communications in medicine (DICOM) format and reconstructed and analyzed with polar maps.","downloadable_attachments":[{"id":44550730,"asset_id":14163037,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33148106,"first_name":"Kenichi","last_name":"Nakajima","domain_name":"kanazawa-u","page_name":"KenichiNakajima","display_name":"Kenichi Nakajima","profile_url":"https://kanazawa-u.academia.edu/KenichiNakajima?f_ri=10035","photo":"/images/s65_no_pic.png"},{"id":33209294,"first_name":"Koichi","last_name":"Okuda","domain_name":"independent","page_name":"KoichiOkuda","display_name":"Koichi Okuda","profile_url":"https://independent.academia.edu/KoichiOkuda?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=10035","nofollow":true},{"id":32696,"name":"Scientific Societies","url":"https://www.academia.edu/Documents/in/Scientific_Societies?f_ri=10035","nofollow":true},{"id":69841,"name":"Standard Deviation","url":"https://www.academia.edu/Documents/in/Standard_Deviation?f_ri=10035"},{"id":72314,"name":"Fatty acids","url":"https://www.academia.edu/Documents/in/Fatty_acids?f_ri=10035"},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":392828,"name":"Myocardium","url":"https://www.academia.edu/Documents/in/Myocardium?f_ri=10035"},{"id":675419,"name":"Sympathetic Nervous System","url":"https://www.academia.edu/Documents/in/Sympathetic_Nervous_System?f_ri=10035"},{"id":784087,"name":"Myocardial Perfusion Imaging","url":"https://www.academia.edu/Documents/in/Myocardial_Perfusion_Imaging?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_21420333" data-work_id="21420333" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/21420333/Components_of_a_Curriculum_for_Molecular_Imaging_Scientists">Components of a Curriculum for Molecular Imaging Scientists</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Molecular imaging is the visualization, characterization, and measurement of biologic processes at the molecular and cellular levels in humans and other living systems (1). It comprises an emerging set of technologies that builds on... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_21420333" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Molecular imaging is the visualization, characterization, and measurement of biologic processes at the molecular and cellular levels in humans and other living systems (1). It comprises an emerging set of technologies that builds on advances in imaging procedures (e.g., PET, SPECT, MRI, ultrasound, optical, and photoacoustic), improved understanding of biology, and the development of molecularly targeted agents. These continuously expanding sets of imaging methods are often used in combination, and advances in data acquisition and analyses facilitate a more complete understanding of biology. Molecular imaging aims to improve our understanding of mammalian biology and lead to advances in patient care by providing targeted therapies that will enable personalized medicine and the imaging tools to assess outcome. Implementation of these new technologies in clinical care has many educational, technical, and regulatory challenges that must be overcome before molecular imaging reaches its full potential. The impact of molecular imaging has been significant in several disciplines, because it represents a paradigm shift in how scientists and clinicians can observe biology in real time and in a relatively noninvasive manner to enable the power of repeated measures in living organisms.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/21420333" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8a6cdf3eb1ba769d29bdabf999cb527d" rel="nofollow" data-download="{"attachment_id":41863848,"asset_id":21420333,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41863848/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="42489775" href="https://mskcc.academia.edu/MichelleBradbury">Michelle Bradbury</a><script data-card-contents-for-user="42489775" type="text/json">{"id":42489775,"first_name":"Michelle","last_name":"Bradbury","domain_name":"mskcc","page_name":"MichelleBradbury","display_name":"Michelle Bradbury","profile_url":"https://mskcc.academia.edu/MichelleBradbury?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_21420333 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="21420333"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 21420333, container: ".js-paper-rank-work_21420333", }); });</script></li><li class="js-percentile-work_21420333 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 21420333; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_21420333"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_21420333 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="21420333"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 21420333; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=21420333]").text(description); $(".js-view-count-work_21420333").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_21420333").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="21420333"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">15</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="140" rel="nofollow" href="https://www.academia.edu/Documents/in/Pharmacology">Pharmacology</a>, <script data-card-contents-for-ri="140" type="text/json">{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="300" rel="nofollow" href="https://www.academia.edu/Documents/in/Mathematics">Mathematics</a>, <script data-card-contents-for-ri="300" type="text/json">{"id":300,"name":"Mathematics","url":"https://www.academia.edu/Documents/in/Mathematics?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="498" rel="nofollow" href="https://www.academia.edu/Documents/in/Physics">Physics</a>, <script data-card-contents-for-ri="498" type="text/json">{"id":498,"name":"Physics","url":"https://www.academia.edu/Documents/in/Physics?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="2513" rel="nofollow" href="https://www.academia.edu/Documents/in/Molecular_Biology">Molecular Biology</a><script data-card-contents-for-ri="2513" type="text/json">{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=21420333]'), work: {"id":21420333,"title":"Components of a Curriculum for Molecular Imaging Scientists","created_at":"2016-02-01T12:10:46.793-08:00","url":"https://www.academia.edu/21420333/Components_of_a_Curriculum_for_Molecular_Imaging_Scientists?f_ri=10035","dom_id":"work_21420333","summary":"Molecular imaging is the visualization, characterization, and measurement of biologic processes at the molecular and cellular levels in humans and other living systems (1). It comprises an emerging set of technologies that builds on advances in imaging procedures (e.g., PET, SPECT, MRI, ultrasound, optical, and photoacoustic), improved understanding of biology, and the development of molecularly targeted agents. These continuously expanding sets of imaging methods are often used in combination, and advances in data acquisition and analyses facilitate a more complete understanding of biology. Molecular imaging aims to improve our understanding of mammalian biology and lead to advances in patient care by providing targeted therapies that will enable personalized medicine and the imaging tools to assess outcome. Implementation of these new technologies in clinical care has many educational, technical, and regulatory challenges that must be overcome before molecular imaging reaches its full potential. The impact of molecular imaging has been significant in several disciplines, because it represents a paradigm shift in how scientists and clinicians can observe biology in real time and in a relatively noninvasive manner to enable the power of repeated measures in living organisms.","downloadable_attachments":[{"id":41863848,"asset_id":21420333,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":42489775,"first_name":"Michelle","last_name":"Bradbury","domain_name":"mskcc","page_name":"MichelleBradbury","display_name":"Michelle Bradbury","profile_url":"https://mskcc.academia.edu/MichelleBradbury?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":140,"name":"Pharmacology","url":"https://www.academia.edu/Documents/in/Pharmacology?f_ri=10035","nofollow":true},{"id":300,"name":"Mathematics","url":"https://www.academia.edu/Documents/in/Mathematics?f_ri=10035","nofollow":true},{"id":498,"name":"Physics","url":"https://www.academia.edu/Documents/in/Physics?f_ri=10035","nofollow":true},{"id":2513,"name":"Molecular Biology","url":"https://www.academia.edu/Documents/in/Molecular_Biology?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035"},{"id":13827,"name":"Cell Biology","url":"https://www.academia.edu/Documents/in/Cell_Biology?f_ri=10035"},{"id":39857,"name":"Molecular Imaging","url":"https://www.academia.edu/Documents/in/Molecular_Imaging?f_ri=10035"},{"id":44057,"name":"Curriculum","url":"https://www.academia.edu/Documents/in/Curriculum?f_ri=10035"},{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035"},{"id":144259,"name":"Goals","url":"https://www.academia.edu/Documents/in/Goals?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":704648,"name":"Clinical Competence","url":"https://www.academia.edu/Documents/in/Clinical_Competence?f_ri=10035"},{"id":772467,"name":"Competency Based Education","url":"https://www.academia.edu/Documents/in/Competency_Based_Education?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"},{"id":820718,"name":"Individualized Medicine","url":"https://www.academia.edu/Documents/in/Individualized_Medicine?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_70421992" data-work_id="70421992" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/70421992/Evaluation_of_image_registration_in_PET_CT_of_the_liver_and_recommendations_for_optimized_imaging">Evaluation of image registration in PET/CT of the liver and recommendations for optimized imaging</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Multimodality PET/CT of the liver can be performed with an integrated (hybrid) PET/CT scanner or with software fusion of dedicated PET and CT. Accurate anatomic correlation and good image quality of both modalities are important... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_70421992" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Multimodality PET/CT of the liver can be performed with an integrated (hybrid) PET/CT scanner or with software fusion of dedicated PET and CT. Accurate anatomic correlation and good image quality of both modalities are important prerequisites, regardless of the applied method. Registration accuracy is influenced by breathing motion differences on PET and CT, which may also have impact on (attenuation correction-related) artifacts, especially in the upper abdomen. The impact of these issues was evaluated for both hybrid PET/CT and software fusion, focused on imaging of the liver. Methods: Thirty patients underwent hybrid PET/CT, 20 with CT during expiration breathhold (EB) and 10 with CT during free breathing (FB). Ten additional patients underwent software fusion of dedicated PET and dedicated expiration breath-hold CT (SF). The image registration accuracy was evaluated at the location of liver borders on CT and uncorrected PET images and at the location of liver lesions. Attenuation-correction artifacts were evaluated by comparison of liver borders on uncorrected and attenuationcorrected PET images. CT images were evaluated for the presence of breathing artifacts. Results: In EB, 40% of patients had an absolute registration error of the diaphragm in the craniocaudal direction of .1 cm (range, 216 to 44 mm), and 45% of lesions were mispositioned .1 cm. In 50% of cases, attenuationcorrection artifacts caused a deformation of the liver dome on PET of .1 cm. Poor compliance to breath-hold instructions caused CT artifacts in 55% of cases. In FB, 30% had registration errors of .1 cm (range, 24 to 16 mm) and PET artifacts were less extensive, but all CT images had breathing artifacts. As SF allows independent alignment of PET and CT, no registration errors or artifacts of .1 cm of the diaphragm occurred. Conclusion: Hybrid PET/CT of the liver may have significant registration errors and artifacts related to breathing motion. The extent of these issues depends on the selected breathing protocol and the speed of the CT scanner. No protocol or scanner can guarantee perfect image fusion. On the basis of these findings, recommendations were formulated with regard to scanner requirements, breathing protocols, and reporting.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/70421992" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="d1da80de5ef76205d3f598fcc6ae9820" rel="nofollow" data-download="{"attachment_id":80181839,"asset_id":70421992,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/80181839/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44848739" href="https://independent.academia.edu/FCorstens">F. Corstens</a><script data-card-contents-for-user="44848739" type="text/json">{"id":44848739,"first_name":"F.","last_name":"Corstens","domain_name":"independent","page_name":"FCorstens","display_name":"F. Corstens","profile_url":"https://independent.academia.edu/FCorstens?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_70421992 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="70421992"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 70421992, container: ".js-paper-rank-work_70421992", }); });</script></li><li class="js-percentile-work_70421992 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 70421992; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_70421992"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_70421992 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="70421992"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 70421992; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=70421992]").text(description); $(".js-view-count-work_70421992").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_70421992").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="70421992"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">17</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="626" rel="nofollow" href="https://www.academia.edu/Documents/in/Oncology">Oncology</a>, <script data-card-contents-for-ri="626" type="text/json">{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23518" rel="nofollow" href="https://www.academia.edu/Documents/in/Positron_Emission_Tomography">Positron Emission Tomography</a>, <script data-card-contents-for-ri="23518" type="text/json">{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a><script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=70421992]'), work: {"id":70421992,"title":"Evaluation of image registration in PET/CT of the liver and recommendations for optimized imaging","created_at":"2022-02-04T06:12:42.735-08:00","url":"https://www.academia.edu/70421992/Evaluation_of_image_registration_in_PET_CT_of_the_liver_and_recommendations_for_optimized_imaging?f_ri=10035","dom_id":"work_70421992","summary":"Multimodality PET/CT of the liver can be performed with an integrated (hybrid) PET/CT scanner or with software fusion of dedicated PET and CT. Accurate anatomic correlation and good image quality of both modalities are important prerequisites, regardless of the applied method. Registration accuracy is influenced by breathing motion differences on PET and CT, which may also have impact on (attenuation correction-related) artifacts, especially in the upper abdomen. The impact of these issues was evaluated for both hybrid PET/CT and software fusion, focused on imaging of the liver. Methods: Thirty patients underwent hybrid PET/CT, 20 with CT during expiration breathhold (EB) and 10 with CT during free breathing (FB). Ten additional patients underwent software fusion of dedicated PET and dedicated expiration breath-hold CT (SF). The image registration accuracy was evaluated at the location of liver borders on CT and uncorrected PET images and at the location of liver lesions. Attenuation-correction artifacts were evaluated by comparison of liver borders on uncorrected and attenuationcorrected PET images. CT images were evaluated for the presence of breathing artifacts. Results: In EB, 40% of patients had an absolute registration error of the diaphragm in the craniocaudal direction of .1 cm (range, 216 to 44 mm), and 45% of lesions were mispositioned .1 cm. In 50% of cases, attenuationcorrection artifacts caused a deformation of the liver dome on PET of .1 cm. Poor compliance to breath-hold instructions caused CT artifacts in 55% of cases. In FB, 30% had registration errors of .1 cm (range, 24 to 16 mm) and PET artifacts were less extensive, but all CT images had breathing artifacts. As SF allows independent alignment of PET and CT, no registration errors or artifacts of .1 cm of the diaphragm occurred. Conclusion: Hybrid PET/CT of the liver may have significant registration errors and artifacts related to breathing motion. The extent of these issues depends on the selected breathing protocol and the speed of the CT scanner. No protocol or scanner can guarantee perfect image fusion. On the basis of these findings, recommendations were formulated with regard to scanner requirements, breathing protocols, and reporting.","downloadable_attachments":[{"id":80181839,"asset_id":70421992,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44848739,"first_name":"F.","last_name":"Corstens","domain_name":"independent","page_name":"FCorstens","display_name":"F. Corstens","profile_url":"https://independent.academia.edu/FCorstens?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":626,"name":"Oncology","url":"https://www.academia.edu/Documents/in/Oncology?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true},{"id":29731,"name":"Image Registration","url":"https://www.academia.edu/Documents/in/Image_Registration?f_ri=10035"},{"id":29916,"name":"PET","url":"https://www.academia.edu/Documents/in/PET?f_ri=10035"},{"id":30415,"name":"Image Quality","url":"https://www.academia.edu/Documents/in/Image_Quality?f_ri=10035"},{"id":71437,"name":"Liver","url":"https://www.academia.edu/Documents/in/Liver?f_ri=10035"},{"id":83038,"name":"Image fusion","url":"https://www.academia.edu/Documents/in/Image_fusion?f_ri=10035"},{"id":93817,"name":"Attenuation Correction","url":"https://www.academia.edu/Documents/in/Attenuation_Correction?f_ri=10035"},{"id":96379,"name":"PET imaging","url":"https://www.academia.edu/Documents/in/PET_imaging?f_ri=10035"},{"id":172678,"name":"Artifacts","url":"https://www.academia.edu/Documents/in/Artifacts?f_ri=10035"},{"id":202428,"name":"Respiration","url":"https://www.academia.edu/Documents/in/Respiration?f_ri=10035"},{"id":220049,"name":"Accuracy","url":"https://www.academia.edu/Documents/in/Accuracy?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=10035"},{"id":3562342,"name":"Liver neoplasms","url":"https://www.academia.edu/Documents/in/Liver_neoplasms?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_68476479" data-work_id="68476479" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/68476479/Diagnostic_value_of_99mTc_ubiquicidin_scintigraphy_for_osteomyelitis_and_comparisons_with_99mTc_methylene_diphosphonate_scintigraphy_and_magnetic_resonance_imaging">Diagnostic value of 99mTc-ubiquicidin scintigraphy for osteomyelitis and comparisons with 99mTc-methylene diphosphonate scintigraphy and magnetic resonance imaging</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Objective The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of inflammation. Currently available techniques cannot decisively address this issue. In this respect,... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_68476479" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Objective The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of inflammation. Currently available techniques cannot decisively address this issue. In this respect, antimicrobial peptide 99m Tc-ubiquicidin (UBI) 29-41 scans have been showing interesting results. The aim of this study was to determine the accuracy of 99m Tc-UBI scan in the detection of osteomyelitis and to compare it with 99m Tc-methylene diphosphonate scan and magnetic resonance imaging (MRI). Methods Twenty patients (mean age = 48.90 years) with suspected osteomyelitis were included in this study. After evaluation of each patient through history taking, physical examination, appropriate laboratory tests, and other processes including bone probing, wound culture, and plain film radiography, MRIs, 99m Tc-UBI scans, and 99m Tc-methylene diphosphonate scans were performed. For quantitative analysis, the mean count of abnormal-tonormal (A/N) region was calculated for images acquired at 15, 30, 45, 60, 120, and 240 min to obtain the most favorable time for imaging. Results In total, osteomyelitis was detected in the 99m Tc-UBI scans of 17 patients, indicating 100% accuracy, compared with an accuracy of 90% for osteomyelitis detected in three-phase bone scans. The maximum mean A/N was observed at 15 min after intravenous injection (median: 1.91; interquartile range: 1.54-2.94). MRI was performed in 12 cases only with 75% accuracy. In addition, the A/N ratios for the 99m Tc-UBI scans were not significantly different between patients with or without Staphylococcus aureus growth on wound cultures. Conclusion For fast imaging with high accuracy, 99m Tc-UBI 29-41 is a suitable choice for the detection of osteomyelitis. Nucl Med Commun 32:716-723 c 2011 Wolters Kluwer Health | Lippincott Williams & Wilkins.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/68476479" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="18ba8f21202b18a2b57d39534c6a1b14" rel="nofollow" data-download="{"attachment_id":78938111,"asset_id":68476479,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/78938111/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50992299" href="https://mums.academia.edu/KamranAryana">Kamran Aryana</a><script data-card-contents-for-user="50992299" type="text/json">{"id":50992299,"first_name":"Kamran","last_name":"Aryana","domain_name":"mums","page_name":"KamranAryana","display_name":"Kamran Aryana","profile_url":"https://mums.academia.edu/KamranAryana?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_68476479 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="68476479"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 68476479, container: ".js-paper-rank-work_68476479", }); 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$(".js-view-count[data-work-id=68476479]").text(description); $(".js-view-count-work_68476479").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_68476479").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="68476479"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">9</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="6200" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging">Magnetic Resonance Imaging</a>, <script data-card-contents-for-ri="6200" type="text/json">{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="26327" rel="nofollow" href="https://www.academia.edu/Documents/in/Medicine">Medicine</a>, <script data-card-contents-for-ri="26327" type="text/json">{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="100540" rel="nofollow" href="https://www.academia.edu/Documents/in/Feasibility_Studies">Feasibility Studies</a><script data-card-contents-for-ri="100540" type="text/json">{"id":100540,"name":"Feasibility Studies","url":"https://www.academia.edu/Documents/in/Feasibility_Studies?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=68476479]'), work: {"id":68476479,"title":"Diagnostic value of 99mTc-ubiquicidin scintigraphy for osteomyelitis and comparisons with 99mTc-methylene diphosphonate scintigraphy and magnetic resonance imaging","created_at":"2022-01-16T22:48:31.766-08:00","url":"https://www.academia.edu/68476479/Diagnostic_value_of_99mTc_ubiquicidin_scintigraphy_for_osteomyelitis_and_comparisons_with_99mTc_methylene_diphosphonate_scintigraphy_and_magnetic_resonance_imaging?f_ri=10035","dom_id":"work_68476479","summary":"Objective The discrimination of bacterial infections from sterile inflammatory processes is of great importance in the management of inflammation. Currently available techniques cannot decisively address this issue. In this respect, antimicrobial peptide 99m Tc-ubiquicidin (UBI) 29-41 scans have been showing interesting results. The aim of this study was to determine the accuracy of 99m Tc-UBI scan in the detection of osteomyelitis and to compare it with 99m Tc-methylene diphosphonate scan and magnetic resonance imaging (MRI). Methods Twenty patients (mean age = 48.90 years) with suspected osteomyelitis were included in this study. After evaluation of each patient through history taking, physical examination, appropriate laboratory tests, and other processes including bone probing, wound culture, and plain film radiography, MRIs, 99m Tc-UBI scans, and 99m Tc-methylene diphosphonate scans were performed. For quantitative analysis, the mean count of abnormal-tonormal (A/N) region was calculated for images acquired at 15, 30, 45, 60, 120, and 240 min to obtain the most favorable time for imaging. Results In total, osteomyelitis was detected in the 99m Tc-UBI scans of 17 patients, indicating 100% accuracy, compared with an accuracy of 90% for osteomyelitis detected in three-phase bone scans. The maximum mean A/N was observed at 15 min after intravenous injection (median: 1.91; interquartile range: 1.54-2.94). MRI was performed in 12 cases only with 75% accuracy. In addition, the A/N ratios for the 99m Tc-UBI scans were not significantly different between patients with or without Staphylococcus aureus growth on wound cultures. Conclusion For fast imaging with high accuracy, 99m Tc-UBI 29-41 is a suitable choice for the detection of osteomyelitis. Nucl Med Commun 32:716-723 c 2011 Wolters Kluwer Health | Lippincott Williams \u0026 Wilkins.","downloadable_attachments":[{"id":78938111,"asset_id":68476479,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50992299,"first_name":"Kamran","last_name":"Aryana","domain_name":"mums","page_name":"KamranAryana","display_name":"Kamran Aryana","profile_url":"https://mums.academia.edu/KamranAryana?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6200,"name":"Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Imaging?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035","nofollow":true},{"id":100540,"name":"Feasibility Studies","url":"https://www.academia.edu/Documents/in/Feasibility_Studies?f_ri=10035","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=10035"},{"id":228045,"name":"Osteomyelitis","url":"https://www.academia.edu/Documents/in/Osteomyelitis?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_63069421" data-work_id="63069421" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" rel="nofollow" href="https://www.academia.edu/63069421/A_dip_into_the_world_of_veterinary_nuclear_medicine_equine_lung_scintigraphy">A dip into the world of veterinary nuclear medicine: equine lung scintigraphy</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/63069421" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="375090c8fd5faa4df3aeab08a108a72a" rel="nofollow" data-download="{"attachment_id":75618450,"asset_id":63069421,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75618450/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="105890830" rel="nofollow" href="https://independent.academia.edu/DominiqueVotion">Dominique Votion</a><script data-card-contents-for-user="105890830" type="text/json">{"id":105890830,"first_name":"Dominique","last_name":"Votion","domain_name":"independent","page_name":"DominiqueVotion","display_name":"Dominique Votion","profile_url":"https://independent.academia.edu/DominiqueVotion?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_63069421 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="63069421"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 63069421, container: ".js-paper-rank-work_63069421", }); 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$(".js-view-count[data-work-id=63069421]").text(description); $(".js-view-count-work_63069421").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_63069421").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="63069421"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="35414" rel="nofollow" href="https://www.academia.edu/Documents/in/Veterinary">Veterinary</a>, <script data-card-contents-for-ri="35414" type="text/json">{"id":35414,"name":"Veterinary","url":"https://www.academia.edu/Documents/in/Veterinary?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="644860" rel="nofollow" href="https://www.academia.edu/Documents/in/Veterinary_Sciences">Veterinary Sciences</a><script data-card-contents-for-ri="644860" type="text/json">{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=63069421]'), work: {"id":63069421,"title":"A dip into the world of veterinary nuclear medicine: equine lung scintigraphy","created_at":"2021-12-03T00:29:27.429-08:00","url":"https://www.academia.edu/63069421/A_dip_into_the_world_of_veterinary_nuclear_medicine_equine_lung_scintigraphy?f_ri=10035","dom_id":"work_63069421","summary":null,"downloadable_attachments":[{"id":75618450,"asset_id":63069421,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":105890830,"first_name":"Dominique","last_name":"Votion","domain_name":"independent","page_name":"DominiqueVotion","display_name":"Dominique Votion","profile_url":"https://independent.academia.edu/DominiqueVotion?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":35414,"name":"Veterinary","url":"https://www.academia.edu/Documents/in/Veterinary?f_ri=10035","nofollow":true},{"id":644860,"name":"Veterinary Sciences","url":"https://www.academia.edu/Documents/in/Veterinary_Sciences?f_ri=10035","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_54063270" data-work_id="54063270" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/54063270/Comparison_of_high_resolution_MRI_and_SPECT_bone_scintigraphy_for_noninvasive_imaging_of_the_temporomandibular_joint">Comparison of high-resolution MRI and SPECT bone scintigraphy for noninvasive imaging of the temporomandibular joint</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Prospective evaluation by magnetic resonance imaging (MRI) and both single photon emission computed tomography (SPECT) and planar bone scintigraphy was undertaken in 31 temporomandibular joints (TMJs) of 21 symptomatic patients. When... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_54063270" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Prospective evaluation by magnetic resonance imaging (MRI) and both single photon emission computed tomography (SPECT) and planar bone scintigraphy was undertaken in 31 temporomandibular joints (TMJs) of 21 symptomatic patients. When compared with the results of subsequent arthrography, MRI (0.88) was more sensitive than SPECT (0.76) or planar (0.56) scintigraphy for detection of internal derangement of the TMJ. A diagnostic sensitivity of 0.96 was achieved when the results of either MRI or SPECT was considered evidence of internal joint derangement. Five symptomatic TMJs, clinically thought to be abnormal, were positive on SPECT but showed no evidence of anterior disk displacement at the time of arthrography. In such instances, SPECT may be detecting functionally significant altered joint mechanics that are not evident on anatomic imaging of the TMJ.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/54063270" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="30fe7428afa2e004a683bb0affe10f56" rel="nofollow" data-download="{"attachment_id":70608530,"asset_id":54063270,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/70608530/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="1912051" href="https://jagiellonian.academia.edu/WojciechFroncisz">Wojciech Froncisz</a><script data-card-contents-for-user="1912051" type="text/json">{"id":1912051,"first_name":"Wojciech","last_name":"Froncisz","domain_name":"jagiellonian","page_name":"WojciechFroncisz","display_name":"Wojciech Froncisz","profile_url":"https://jagiellonian.academia.edu/WojciechFroncisz?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_54063270 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="54063270"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 54063270, container: ".js-paper-rank-work_54063270", }); 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$(".js-view-count[data-work-id=54063270]").text(description); $(".js-view-count-work_54063270").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_54063270").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="54063270"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">10</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="9054" rel="nofollow" href="https://www.academia.edu/Documents/in/Temporomandibular_Joint">Temporomandibular Joint</a>, <script data-card-contents-for-ri="9054" type="text/json">{"id":9054,"name":"Temporomandibular Joint","url":"https://www.academia.edu/Documents/in/Temporomandibular_Joint?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="21732" rel="nofollow" href="https://www.academia.edu/Documents/in/Magnetic_Resonance_Spectroscopy">Magnetic Resonance Spectroscopy</a>, <script data-card-contents-for-ri="21732" type="text/json">{"id":21732,"name":"Magnetic Resonance Spectroscopy","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Spectroscopy?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a><script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=54063270]'), work: {"id":54063270,"title":"Comparison of high-resolution MRI and SPECT bone scintigraphy for noninvasive imaging of the temporomandibular joint","created_at":"2021-09-29T16:18:43.064-07:00","url":"https://www.academia.edu/54063270/Comparison_of_high_resolution_MRI_and_SPECT_bone_scintigraphy_for_noninvasive_imaging_of_the_temporomandibular_joint?f_ri=10035","dom_id":"work_54063270","summary":"Prospective evaluation by magnetic resonance imaging (MRI) and both single photon emission computed tomography (SPECT) and planar bone scintigraphy was undertaken in 31 temporomandibular joints (TMJs) of 21 symptomatic patients. When compared with the results of subsequent arthrography, MRI (0.88) was more sensitive than SPECT (0.76) or planar (0.56) scintigraphy for detection of internal derangement of the TMJ. A diagnostic sensitivity of 0.96 was achieved when the results of either MRI or SPECT was considered evidence of internal joint derangement. Five symptomatic TMJs, clinically thought to be abnormal, were positive on SPECT but showed no evidence of anterior disk displacement at the time of arthrography. In such instances, SPECT may be detecting functionally significant altered joint mechanics that are not evident on anatomic imaging of the TMJ.","downloadable_attachments":[{"id":70608530,"asset_id":54063270,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":1912051,"first_name":"Wojciech","last_name":"Froncisz","domain_name":"jagiellonian","page_name":"WojciechFroncisz","display_name":"Wojciech Froncisz","profile_url":"https://jagiellonian.academia.edu/WojciechFroncisz?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":9054,"name":"Temporomandibular Joint","url":"https://www.academia.edu/Documents/in/Temporomandibular_Joint?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":21732,"name":"Magnetic Resonance Spectroscopy","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance_Spectroscopy?f_ri=10035","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=10035","nofollow":true},{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":309086,"name":"High Resolution","url":"https://www.academia.edu/Documents/in/High_Resolution?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":1265784,"name":"Bone Scintigraphy","url":"https://www.academia.edu/Documents/in/Bone_Scintigraphy?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48406674" data-work_id="48406674" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48406674/Ventilation_perfusion_scintigraphy_in_the_PIOPED_study_Part_I_Data_collection_and_tabulation">Ventilation-perfusion scintigraphy in the PIOPED study. Part I. Data collection and tabulation</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study of more than 700 patients is the largest existing study of the accuracy of lung scintigraphy in the diagnosis of acute pulmonary embolism. Perfusion scans were... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48406674" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study of more than 700 patients is the largest existing study of the accuracy of lung scintigraphy in the diagnosis of acute pulmonary embolism. Perfusion scans were obtained in all patients and ventilation scans in almost all, using standardized techniques. Chest radiographs were obtained in all patients within 12 hr of the lung scan. Most patients underwent pulmonary arteriography. The images were interpreted according to a set of interpretive criteria which remained constant throughout the trial. A standardized, detailed description of each image set was derived by consensus of teams of two readers blinded to clinical and arteriographic findings. This communication reports the methods used to describe and categorize the ventilation-perfusion scintigrams obtained in patients who were enrolled in the PIOPED study. Scintigraphic technique is reviewed briefly, probability assessment is described and the scan descr...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48406674" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="ded1657499ebc309b36020f2665a8ed4" rel="nofollow" data-download="{"attachment_id":67035852,"asset_id":48406674,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67035852/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35178064" href="https://spanalumni.academia.edu/JerryFroelich">Jerry Froelich</a><script data-card-contents-for-user="35178064" type="text/json">{"id":35178064,"first_name":"Jerry","last_name":"Froelich","domain_name":"spanalumni","page_name":"JerryFroelich","display_name":"Jerry Froelich","profile_url":"https://spanalumni.academia.edu/JerryFroelich?f_ri=10035","photo":"https://0.academia-photos.com/35178064/10223107/11408645/s65_jerry.froelich.jpg"}</script></span></span></li><li class="js-paper-rank-work_48406674 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48406674"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48406674, container: ".js-paper-rank-work_48406674", }); 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Part I. Data collection and tabulation","created_at":"2021-05-04T17:30:05.145-07:00","url":"https://www.academia.edu/48406674/Ventilation_perfusion_scintigraphy_in_the_PIOPED_study_Part_I_Data_collection_and_tabulation?f_ri=10035","dom_id":"work_48406674","summary":"The Prospective Investigation of Pulmonary Embolism Diagnosis (PIOPED) study of more than 700 patients is the largest existing study of the accuracy of lung scintigraphy in the diagnosis of acute pulmonary embolism. Perfusion scans were obtained in all patients and ventilation scans in almost all, using standardized techniques. Chest radiographs were obtained in all patients within 12 hr of the lung scan. Most patients underwent pulmonary arteriography. The images were interpreted according to a set of interpretive criteria which remained constant throughout the trial. A standardized, detailed description of each image set was derived by consensus of teams of two readers blinded to clinical and arteriographic findings. This communication reports the methods used to describe and categorize the ventilation-perfusion scintigrams obtained in patients who were enrolled in the PIOPED study. Scintigraphic technique is reviewed briefly, probability assessment is described and the scan descr...","downloadable_attachments":[{"id":67035852,"asset_id":48406674,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35178064,"first_name":"Jerry","last_name":"Froelich","domain_name":"spanalumni","page_name":"JerryFroelich","display_name":"Jerry Froelich","profile_url":"https://spanalumni.academia.edu/JerryFroelich?f_ri=10035","photo":"https://0.academia-photos.com/35178064/10223107/11408645/s65_jerry.froelich.jpg"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=10035","nofollow":true},{"id":102587,"name":"Pulmonary Embolism","url":"https://www.academia.edu/Documents/in/Pulmonary_Embolism?f_ri=10035","nofollow":true},{"id":153168,"name":"Data Collection","url":"https://www.academia.edu/Documents/in/Data_Collection?f_ri=10035"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=10035"},{"id":197297,"name":"Lung","url":"https://www.academia.edu/Documents/in/Lung?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=10035"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=10035"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_9772388" data-work_id="9772388" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/9772388/New_Technologies_in_Radiation_Oncology">New Technologies in Radiation Oncology</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">New Technologies in Radiation Oncology provides an excellent overview of recent technologic developments in the field of radiation oncology. This book is intended for physicians and medical physicists who are working in radiation oncology... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_9772388" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">New Technologies in Radiation Oncology provides an excellent overview of recent technologic developments in the field of radiation oncology. This book is intended for physicians and medical physicists who are working in radiation oncology and those just entering the field. It encompasses a broad range of new technologies in radiation therapy-from image acquisition and processing to treatment planning to therapy-and helps the reader grasp the basic ideas of each new technology. If the reader wants more information than the book provides, each chapter includes a wealth of references for learning about a particular subject in detail.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/9772388" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="7fa01f26066129ce7a4780c36255c9e3" rel="nofollow" data-download="{"attachment_id":47651802,"asset_id":9772388,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/47651802/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="23528754" href="https://uaic.academia.edu/dandan">dan dan</a><script data-card-contents-for-user="23528754" type="text/json">{"id":23528754,"first_name":"dan","last_name":"dan","domain_name":"uaic","page_name":"dandan","display_name":"dan dan","profile_url":"https://uaic.academia.edu/dandan?f_ri=10035","photo":"https://0.academia-photos.com/23528754/6375861/7213863/s65_dan.dan.jpg_oh_722c7e869bc0c00accde4010ae7b96f7_oe_551026e4___gda___1426573537_231e064d9184650318a4014758b91df7"}</script></span></span></li><li class="js-paper-rank-work_9772388 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="9772388"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 9772388, container: ".js-paper-rank-work_9772388", }); 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This book is intended for physicians and medical physicists who are working in radiation oncology and those just entering the field. It encompasses a broad range of new technologies in radiation therapy-from image acquisition and processing to treatment planning to therapy-and helps the reader grasp the basic ideas of each new technology. If the reader wants more information than the book provides, each chapter includes a wealth of references for learning about a particular subject in detail.","downloadable_attachments":[{"id":47651802,"asset_id":9772388,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":23528754,"first_name":"dan","last_name":"dan","domain_name":"uaic","page_name":"dandan","display_name":"dan dan","profile_url":"https://uaic.academia.edu/dandan?f_ri=10035","photo":"https://0.academia-photos.com/23528754/6375861/7213863/s65_dan.dan.jpg_oh_722c7e869bc0c00accde4010ae7b96f7_oe_551026e4___gda___1426573537_231e064d9184650318a4014758b91df7"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":59546,"name":"New Technology","url":"https://www.academia.edu/Documents/in/New_Technology?f_ri=10035","nofollow":true},{"id":74754,"name":"3-D Imaging","url":"https://www.academia.edu/Documents/in/3-D_Imaging?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":737256,"name":"Treatment planning","url":"https://www.academia.edu/Documents/in/Treatment_planning?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_12209460" data-work_id="12209460" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/12209460/131_I_123_I_Metaiodobenzylguanidine_MIBG_scintigraphy_procedure_guidelines_for_tumour_imaging">131 I/ 123 I-Metaiodobenzylguanidine (MIBG) scintigraphy: procedure guidelines for tumour imaging</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">This guideline summarizes the views of the Oncology Committee of the EANM and reflects recommendations for which the EANM cannot be held responsible. The recommendations should be taken in the context of good practice of nuclear medicine... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_12209460" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">This guideline summarizes the views of the Oncology Committee of the EANM and reflects recommendations for which the EANM cannot be held responsible. The recommendations should be taken in the context of good practice of nuclear medicine and do not substitute for national and international legal or regulatory provisions.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/12209460" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2be44408a4573cd5c80e3a286b0cb500" rel="nofollow" data-download="{"attachment_id":46300322,"asset_id":12209460,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/46300322/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="30682131" href="https://independent.academia.edu/LorenzoMaffioli">Lorenzo Maffioli</a><script data-card-contents-for-user="30682131" type="text/json">{"id":30682131,"first_name":"Lorenzo","last_name":"Maffioli","domain_name":"independent","page_name":"LorenzoMaffioli","display_name":"Lorenzo Maffioli","profile_url":"https://independent.academia.edu/LorenzoMaffioli?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_12209460 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="12209460"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 12209460, container: ".js-paper-rank-work_12209460", }); 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The recommendations should be taken in the context of good practice of nuclear medicine and do not substitute for national and international legal or regulatory provisions.","downloadable_attachments":[{"id":46300322,"asset_id":12209460,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":30682131,"first_name":"Lorenzo","last_name":"Maffioli","domain_name":"independent","page_name":"LorenzoMaffioli","display_name":"Lorenzo Maffioli","profile_url":"https://independent.academia.edu/LorenzoMaffioli?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":44507,"name":"Nuclear","url":"https://www.academia.edu/Documents/in/Nuclear?f_ri=10035","nofollow":true},{"id":64900,"name":"Medical Oncology","url":"https://www.academia.edu/Documents/in/Medical_Oncology?f_ri=10035","nofollow":true},{"id":75826,"name":"Europe","url":"https://www.academia.edu/Documents/in/Europe?f_ri=10035","nofollow":true},{"id":173135,"name":"Radionuclide imaging","url":"https://www.academia.edu/Documents/in/Radionuclide_imaging?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":279027,"name":"European","url":"https://www.academia.edu/Documents/in/European?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":446717,"name":"Patient Care","url":"https://www.academia.edu/Documents/in/Patient_Care?f_ri=10035"},{"id":469018,"name":"Neoplasms","url":"https://www.academia.edu/Documents/in/Neoplasms?f_ri=10035"},{"id":532278,"name":"Cancer Patient","url":"https://www.academia.edu/Documents/in/Cancer_Patient?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"},{"id":1233105,"name":"Neuroendocrine Tumors","url":"https://www.academia.edu/Documents/in/Neuroendocrine_Tumors?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_16039580" data-work_id="16039580" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/16039580/99mTc_red_blood_cells_for_detection_of_gastrointestinal_bleeding_experience_with_80_patients">99mTc red blood cells for detection of gastrointestinal bleeding: experience with 80 patients</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Imaging was done in 80 patients with gastrointestinal hemorrhage using red blood cells labeled with 99mTc by a modified in vivo technique. Bleeding was detected in 65% of 40 patients with bright red blood per rectum, 71% of 35 patients... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_16039580" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Imaging was done in 80 patients with gastrointestinal hemorrhage using red blood cells labeled with 99mTc by a modified in vivo technique. Bleeding was detected in 65% of 40 patients with bright red blood per rectum, 71% of 35 patients with melena, and in none of the five patients with occult bleeding and chronic anemia. No clinical evidence of further</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/16039580" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="c114a86b9034df7be484f5c1c938da76" rel="nofollow" data-download="{"attachment_id":42775091,"asset_id":16039580,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/42775091/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35178064" href="https://spanalumni.academia.edu/JerryFroelich">Jerry Froelich</a><script data-card-contents-for-user="35178064" type="text/json">{"id":35178064,"first_name":"Jerry","last_name":"Froelich","domain_name":"spanalumni","page_name":"JerryFroelich","display_name":"Jerry Froelich","profile_url":"https://spanalumni.academia.edu/JerryFroelich?f_ri=10035","photo":"https://0.academia-photos.com/35178064/10223107/11408645/s65_jerry.froelich.jpg"}</script></span></span></li><li class="js-paper-rank-work_16039580 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="16039580"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 16039580, container: ".js-paper-rank-work_16039580", }); 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Bleeding was detected in 65% of 40 patients with bright red blood per rectum, 71% of 35 patients with melena, and in none of the five patients with occult bleeding and chronic anemia. No clinical evidence of further","downloadable_attachments":[{"id":42775091,"asset_id":16039580,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35178064,"first_name":"Jerry","last_name":"Froelich","domain_name":"spanalumni","page_name":"JerryFroelich","display_name":"Jerry Froelich","profile_url":"https://spanalumni.academia.edu/JerryFroelich?f_ri=10035","photo":"https://0.academia-photos.com/35178064/10223107/11408645/s65_jerry.froelich.jpg"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":92288,"name":"Beta decay","url":"https://www.academia.edu/Documents/in/Beta_decay?f_ri=10035","nofollow":true},{"id":151448,"name":"American","url":"https://www.academia.edu/Documents/in/American?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":336223,"name":"Digestive System","url":"https://www.academia.edu/Documents/in/Digestive_System?f_ri=10035"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=10035"},{"id":534035,"name":"Technetium","url":"https://www.academia.edu/Documents/in/Technetium?f_ri=10035"},{"id":537759,"name":"Gastrointestinal Tract","url":"https://www.academia.edu/Documents/in/Gastrointestinal_Tract?f_ri=10035"},{"id":579219,"name":"Red blood cell","url":"https://www.academia.edu/Documents/in/Red_blood_cell?f_ri=10035"},{"id":982534,"name":"Erythrocytes","url":"https://www.academia.edu/Documents/in/Erythrocytes?f_ri=10035"},{"id":1311469,"name":"Blood cells","url":"https://www.academia.edu/Documents/in/Blood_cells?f_ri=10035"},{"id":1341074,"name":"Isotope Labeling","url":"https://www.academia.edu/Documents/in/Isotope_Labeling?f_ri=10035"},{"id":1607851,"name":"Melena","url":"https://www.academia.edu/Documents/in/Melena?f_ri=10035"},{"id":1607852,"name":"Gastrointestinal bleeding","url":"https://www.academia.edu/Documents/in/Gastrointestinal_bleeding?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_63167114" data-work_id="63167114" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/63167114/Prostate_Cancer_Detection_of_Lymph_Node_Metastases_Outside_the_Routine_Surgical_Area_with_Ferumoxtran_10_enhanced_MR_Imaging_1">Prostate Cancer : Detection of Lymph Node Metastases Outside the Routine Surgical Area with Ferumoxtran-10 – enhanced MR Imaging 1</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Roel A. M. Heesakkers, MD Gerrit J. Jager, MD, PhD Anke M. Hövels, MSc Bartjan de Hoop, MD Harrie C. M. van den Bosch, MD Frank Raat, MD J. Alfred Witjes, MD, PhD Peter F. A. Mulders, MD, PhD Christina Hulsbergen van der Kaa, MD, PhD... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_63167114" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Roel A. M. Heesakkers, MD Gerrit J. Jager, MD, PhD Anke M. Hövels, MSc Bartjan de Hoop, MD Harrie C. M. van den Bosch, MD Frank Raat, MD J. Alfred Witjes, MD, PhD Peter F. A. Mulders, MD, PhD Christina Hulsbergen van der Kaa, MD, PhD Jelle O. Barentsz, MD, PhD Purpose: To prospectively evaluate the feasibility of magnetic resonance (MR) imaging with ferumoxtran-10 in patients with prostate cancer to depict lymph node metastases outside the routine pelvic lymph node dissection (PLND) area.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/63167114" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="0a2336961dd5239c61b5091e063264c7" rel="nofollow" data-download="{"attachment_id":75680306,"asset_id":63167114,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75680306/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="190838749" href="https://independent.academia.edu/Barentsz">Jelle Barentsz</a><script data-card-contents-for-user="190838749" type="text/json">{"id":190838749,"first_name":"Jelle","last_name":"Barentsz","domain_name":"independent","page_name":"Barentsz","display_name":"Jelle Barentsz","profile_url":"https://independent.academia.edu/Barentsz?f_ri=10035","photo":"https://0.academia-photos.com/190838749/53924243/42059011/s65_jelle.barentsz.jpeg"}</script></span></span></li><li class="js-paper-rank-work_63167114 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="63167114"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 63167114, container: ".js-paper-rank-work_63167114", }); 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M. Heesakkers, MD Gerrit J. Jager, MD, PhD Anke M. Hövels, MSc Bartjan de Hoop, MD Harrie C. M. van den Bosch, MD Frank Raat, MD J. Alfred Witjes, MD, PhD Peter F. A. Mulders, MD, PhD Christina Hulsbergen van der Kaa, MD, PhD Jelle O. Barentsz, MD, PhD Purpose: To prospectively evaluate the feasibility of magnetic resonance (MR) imaging with ferumoxtran-10 in patients with prostate cancer to depict lymph node metastases outside the routine pelvic lymph node dissection (PLND) area.","downloadable_attachments":[{"id":75680306,"asset_id":63167114,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":190838749,"first_name":"Jelle","last_name":"Barentsz","domain_name":"independent","page_name":"Barentsz","display_name":"Jelle Barentsz","profile_url":"https://independent.academia.edu/Barentsz?f_ri=10035","photo":"https://0.academia-photos.com/190838749/53924243/42059011/s65_jelle.barentsz.jpeg"}],"research_interests":[{"id":640,"name":"Radiology","url":"https://www.academia.edu/Documents/in/Radiology?f_ri=10035","nofollow":true},{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery?f_ri=10035","nofollow":true},{"id":6021,"name":"Cancer","url":"https://www.academia.edu/Documents/in/Cancer?f_ri=10035","nofollow":true},{"id":8562,"name":"Informed Consent","url":"https://www.academia.edu/Documents/in/Informed_Consent?f_ri=10035","nofollow":true},{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=10035"},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035"},{"id":12980,"name":"Prostate Cancer","url":"https://www.academia.edu/Documents/in/Prostate_Cancer?f_ri=10035"},{"id":119259,"name":"Magnetic Resonance","url":"https://www.academia.edu/Documents/in/Magnetic_Resonance?f_ri=10035"},{"id":1024379,"name":"Nuclear Magnetic Resonance Imaging","url":"https://www.academia.edu/Documents/in/Nuclear_Magnetic_Resonance_Imaging?f_ri=10035"},{"id":1122411,"name":"Mr Imaging","url":"https://www.academia.edu/Documents/in/Mr_Imaging?f_ri=10035"},{"id":1186440,"name":"Prostate Specific Antigen","url":"https://www.academia.edu/Documents/in/Prostate_Specific_Antigen?f_ri=10035"},{"id":3574523,"name":"High risk","url":"https://www.academia.edu/Documents/in/High_risk?f_ri=10035"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_62836750" data-work_id="62836750" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/62836750/Update_on_Guidelines">Update on Guidelines</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/62836750" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="8f2b1f7fb97f0bf7e7022f5910cf547e" rel="nofollow" data-download="{"attachment_id":75476173,"asset_id":62836750,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/75476173/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="71117083" href="https://independent.academia.edu/dominiquedelbeke">dominique delbeke</a><script data-card-contents-for-user="71117083" type="text/json">{"id":71117083,"first_name":"dominique","last_name":"delbeke","domain_name":"independent","page_name":"dominiquedelbeke","display_name":"dominique delbeke","profile_url":"https://independent.academia.edu/dominiquedelbeke?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_62836750 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="62836750"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 62836750, container: ".js-paper-rank-work_62836750", }); 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$(".js-view-count[data-work-id=62836750]").text(description); $(".js-view-count-work_62836750").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_62836750").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="62836750"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">6</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="23518" rel="nofollow" href="https://www.academia.edu/Documents/in/Positron_Emission_Tomography">Positron Emission Tomography</a>, <script data-card-contents-for-ri="23518" type="text/json">{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="32696" rel="nofollow" href="https://www.academia.edu/Documents/in/Scientific_Societies">Scientific Societies</a>, <script data-card-contents-for-ri="32696" type="text/json">{"id":32696,"name":"Scientific Societies","url":"https://www.academia.edu/Documents/in/Scientific_Societies?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="176555" rel="nofollow" href="https://www.academia.edu/Documents/in/Multimodal_imaging">Multimodal imaging</a><script data-card-contents-for-ri="176555" type="text/json">{"id":176555,"name":"Multimodal imaging","url":"https://www.academia.edu/Documents/in/Multimodal_imaging?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=62836750]'), work: {"id":62836750,"title":"Update on Guidelines","created_at":"2021-12-01T03:31:56.454-08:00","url":"https://www.academia.edu/62836750/Update_on_Guidelines?f_ri=10035","dom_id":"work_62836750","summary":null,"downloadable_attachments":[{"id":75476173,"asset_id":62836750,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":71117083,"first_name":"dominique","last_name":"delbeke","domain_name":"independent","page_name":"dominiquedelbeke","display_name":"dominique delbeke","profile_url":"https://independent.academia.edu/dominiquedelbeke?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true},{"id":32696,"name":"Scientific Societies","url":"https://www.academia.edu/Documents/in/Scientific_Societies?f_ri=10035","nofollow":true},{"id":176555,"name":"Multimodal imaging","url":"https://www.academia.edu/Documents/in/Multimodal_imaging?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":959921,"name":"X ray Computed Tomography","url":"https://www.academia.edu/Documents/in/X_ray_Computed_Tomography?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_51696614" data-work_id="51696614" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/51696614/PET_Instrumentation_and_Reconstruction_Algorithms_in_Whole_Body_Applications">PET Instrumentation and Reconstruction Algorithms in Whole-Body Applications</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The aim of this work is the presentation and comparison of state-of-the-art dedicated PET systems actually available on the market, in terms of physical performance and technical features. Particular attention has been given to evaluate... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_51696614" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The aim of this work is the presentation and comparison of state-of-the-art dedicated PET systems actually available on the market, in terms of physical performance and technical features. Particular attention has been given to evaluate the whole-body performance by sensitivity, spatial resolution, dead time, noise equivalent counting rate (NECR), and scatter fraction. PET/CT systems were also included as new proposals to improve diagnostic accuracy of PET, allowing effective anatomic integration to functional data. An overview of actually implemented reconstruction algorithms is also reported to fully understand all of the factors that contribute to image quality.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51696614" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a04bf96b283d030a1309144bf6721dad" rel="nofollow" data-download="{"attachment_id":69305807,"asset_id":51696614,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69305807/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="36291085" href="https://independent.academia.edu/FeliciaZito">Felicia Zito</a><script data-card-contents-for-user="36291085" type="text/json">{"id":36291085,"first_name":"Felicia","last_name":"Zito","domain_name":"independent","page_name":"FeliciaZito","display_name":"Felicia Zito","profile_url":"https://independent.academia.edu/FeliciaZito?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_51696614 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="51696614"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 51696614, container: ".js-paper-rank-work_51696614", }); 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$(".js-view-count[data-work-id=51696614]").text(description); $(".js-view-count-work_51696614").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_51696614").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="51696614"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">5</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71001" rel="nofollow" href="https://www.academia.edu/Documents/in/Image_Reconstruction">Image Reconstruction</a>, <script data-card-contents-for-ri="71001" type="text/json">{"id":71001,"name":"Image Reconstruction","url":"https://www.academia.edu/Documents/in/Image_Reconstruction?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a>, <script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="422089" rel="nofollow" href="https://www.academia.edu/Documents/in/Physical_Performance">Physical Performance</a><script data-card-contents-for-ri="422089" type="text/json">{"id":422089,"name":"Physical Performance","url":"https://www.academia.edu/Documents/in/Physical_Performance?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=51696614]'), work: {"id":51696614,"title":"PET Instrumentation and Reconstruction Algorithms in Whole-Body Applications","created_at":"2021-09-10T02:24:11.555-07:00","url":"https://www.academia.edu/51696614/PET_Instrumentation_and_Reconstruction_Algorithms_in_Whole_Body_Applications?f_ri=10035","dom_id":"work_51696614","summary":"The aim of this work is the presentation and comparison of state-of-the-art dedicated PET systems actually available on the market, in terms of physical performance and technical features. Particular attention has been given to evaluate the whole-body performance by sensitivity, spatial resolution, dead time, noise equivalent counting rate (NECR), and scatter fraction. PET/CT systems were also included as new proposals to improve diagnostic accuracy of PET, allowing effective anatomic integration to functional data. An overview of actually implemented reconstruction algorithms is also reported to fully understand all of the factors that contribute to image quality.","downloadable_attachments":[{"id":69305807,"asset_id":51696614,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":36291085,"first_name":"Felicia","last_name":"Zito","domain_name":"independent","page_name":"FeliciaZito","display_name":"Felicia Zito","profile_url":"https://independent.academia.edu/FeliciaZito?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":71001,"name":"Image Reconstruction","url":"https://www.academia.edu/Documents/in/Image_Reconstruction?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":422089,"name":"Physical Performance","url":"https://www.academia.edu/Documents/in/Physical_Performance?f_ri=10035","nofollow":true},{"id":1281407,"name":"Whole Body","url":"https://www.academia.edu/Documents/in/Whole_Body?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_51206265" data-work_id="51206265" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/51206265/Practical_SPECT_CT_in_Nuclear_Medicine">Practical SPECT/CT in Nuclear Medicine</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Today SPECT/CT has become standard in many imaging pathways, and thus there is a great need for information on how to achieve optimal SPECT/CT images. SPECT/CT can provide unique information that would otherwise be unavailable if SPECT... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_51206265" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Today SPECT/CT has become standard in many imaging pathways, and thus there is a great need for information on how to achieve optimal SPECT/CT images. SPECT/CT can provide unique information that would otherwise be unavailable if SPECT and CT were used in isolation from each other. This unique information can assist in important decision making about patient diagnosis and management. The technologic advances made for PET/CT have no doubt advantaged the progression of SPECT/CT technology and perhaps influenced clinicians in their purchasing decisions in relation to hybrid imaging more generally. Although intended primarily for radiographers and nuclear medicine technologists who work with SPECT/CT, this book is also valuable for other professionals within medical imaging. Practical insight is given into SPECT/CT, some of its uses are outlined, and how to perform some of the more common procedures is explained. For nuclear medicine professionals, a fairly large amount of material on or related to CT has been included, but a tremendous amount of information on nuclear medicine has purposely not been included. The book is divided into 5 parts and 13 chapters written by 16 experts, mostly from the United Kingdom. Part I, with 5 chapters, was written by physicists and diagnostic radiographers and considers the physics and equipment for the operation of a SPECT/CT system. Chapters 2 and 3 discuss basic electromagnetic radiation, beam characteristics, CT image quality, and radiation dose to the patient. Chapter 4 deals with basic g-camera SPECT, and chapter 5 is dedicated to CT instrumentation and quality control. Part II, with 2 chapters, considers practical information needed to implement a SPECT/CT system into a clinic. Chapter 6 elaborates on considerations in choosing a system, and chapter 7 advises on facility and room designs for housing a SPECT/CT system. Part III, with 1 chapter, addresses medical uses of SPECT/CT and includes many SPECT/CT cases and images. Part IV has 2 chapters. Chapter 9 deals with radiation protection within the hybrid SPECT/CT environment, and chapter 10 covers optimization of CT acquisition parameters. Part V, with 3 chapters, outlines a practical perspective on using SPECT/CT. Chapter 11 reviews cross-sectional anatomy for CT positioning purposes, and chapter 12 considers radiographic contrast media and injection systems used in CT. The final chapter, 13, outlines a range of common SPECT/CT procedures with suggested protocols for achieving a successful scan. This book is a practical guide to SPECT/CT imaging with good illustrations. The references are updated, and the index is helpful. I highly recommend this book to trainees and practitioners in nuclear medicine, radiology, and medical physics.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/51206265" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f7d620bb3c19ada2cb40f6fd5128426f" rel="nofollow" data-download="{"attachment_id":69025853,"asset_id":51206265,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/69025853/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="46204312" href="https://independent.academia.edu/HoggPeter">Peter Hogg</a><script data-card-contents-for-user="46204312" type="text/json">{"id":46204312,"first_name":"Peter","last_name":"Hogg","domain_name":"independent","page_name":"HoggPeter","display_name":"Peter Hogg","profile_url":"https://independent.academia.edu/HoggPeter?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_51206265 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="51206265"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 51206265, container: ".js-paper-rank-work_51206265", }); });</script></li><li class="js-percentile-work_51206265 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 51206265; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_51206265"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_51206265 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="51206265"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 51206265; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=51206265]").text(description); $(".js-view-count-work_51206265").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_51206265").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="51206265"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">2</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=51206265]'), work: {"id":51206265,"title":"Practical SPECT/CT in Nuclear Medicine","created_at":"2021-09-03T11:47:47.290-07:00","url":"https://www.academia.edu/51206265/Practical_SPECT_CT_in_Nuclear_Medicine?f_ri=10035","dom_id":"work_51206265","summary":"Today SPECT/CT has become standard in many imaging pathways, and thus there is a great need for information on how to achieve optimal SPECT/CT images. SPECT/CT can provide unique information that would otherwise be unavailable if SPECT and CT were used in isolation from each other. This unique information can assist in important decision making about patient diagnosis and management. The technologic advances made for PET/CT have no doubt advantaged the progression of SPECT/CT technology and perhaps influenced clinicians in their purchasing decisions in relation to hybrid imaging more generally. Although intended primarily for radiographers and nuclear medicine technologists who work with SPECT/CT, this book is also valuable for other professionals within medical imaging. Practical insight is given into SPECT/CT, some of its uses are outlined, and how to perform some of the more common procedures is explained. For nuclear medicine professionals, a fairly large amount of material on or related to CT has been included, but a tremendous amount of information on nuclear medicine has purposely not been included. The book is divided into 5 parts and 13 chapters written by 16 experts, mostly from the United Kingdom. Part I, with 5 chapters, was written by physicists and diagnostic radiographers and considers the physics and equipment for the operation of a SPECT/CT system. Chapters 2 and 3 discuss basic electromagnetic radiation, beam characteristics, CT image quality, and radiation dose to the patient. Chapter 4 deals with basic g-camera SPECT, and chapter 5 is dedicated to CT instrumentation and quality control. Part II, with 2 chapters, considers practical information needed to implement a SPECT/CT system into a clinic. Chapter 6 elaborates on considerations in choosing a system, and chapter 7 advises on facility and room designs for housing a SPECT/CT system. Part III, with 1 chapter, addresses medical uses of SPECT/CT and includes many SPECT/CT cases and images. Part IV has 2 chapters. Chapter 9 deals with radiation protection within the hybrid SPECT/CT environment, and chapter 10 covers optimization of CT acquisition parameters. Part V, with 3 chapters, outlines a practical perspective on using SPECT/CT. Chapter 11 reviews cross-sectional anatomy for CT positioning purposes, and chapter 12 considers radiographic contrast media and injection systems used in CT. The final chapter, 13, outlines a range of common SPECT/CT procedures with suggested protocols for achieving a successful scan. This book is a practical guide to SPECT/CT imaging with good illustrations. The references are updated, and the index is helpful. I highly recommend this book to trainees and practitioners in nuclear medicine, radiology, and medical physics.","downloadable_attachments":[{"id":69025853,"asset_id":51206265,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46204312,"first_name":"Peter","last_name":"Hogg","domain_name":"independent","page_name":"HoggPeter","display_name":"Peter Hogg","profile_url":"https://independent.academia.edu/HoggPeter?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_48366239" data-work_id="48366239" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/48366239/Consequences_of_using_a_simplified_kinetic_model_for_dynamic_PET_data">Consequences of using a simplified kinetic model for dynamic PET data</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">We compared a physiological model of 82Rb kinetics in the myocardium with two reduced-order models to determine their usefulness in assessing physiological parameters from dynamic PET data. A three-compartment model of 82Rb in the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_48366239" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">We compared a physiological model of 82Rb kinetics in the myocardium with two reduced-order models to determine their usefulness in assessing physiological parameters from dynamic PET data. A three-compartment model of 82Rb in the myocardium was used to simulate kinetic PET ROI data. Simulations were generated for eight different blood-flow rates reflecting the physiological range of interest. Two reduced-order models commonly used with myocardial PET studies were fit to the simulated data, and parameters of the reduced-order models were compared with the physiological parameters. Then all three models were fit to the simulated data with noise added. Monte Carlo simulations were used to evaluate and compare the diagnostic utility of the reduced-order models. A description length criterion was used to assess goodness of fit for each model. Finally, fits to simulated data were compared with fits to actual dynamic PET data. Fits of the reduced-order models to the three-compartment mode...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/48366239" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="de29e2b6b1eee9df2279bbe318ba62e8" rel="nofollow" data-download="{"attachment_id":67026551,"asset_id":48366239,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/67026551/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="39554629" href="https://independent.academia.edu/LBorland">L. Borland</a><script data-card-contents-for-user="39554629" type="text/json">{"id":39554629,"first_name":"L.","last_name":"Borland","domain_name":"independent","page_name":"LBorland","display_name":"L. Borland","profile_url":"https://independent.academia.edu/LBorland?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_48366239 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="48366239"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 48366239, container: ".js-paper-rank-work_48366239", }); });</script></li><li class="js-percentile-work_48366239 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 48366239; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_48366239"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_48366239 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="48366239"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 48366239; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=48366239]").text(description); $(".js-view-count-work_48366239").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_48366239").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="48366239"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1131" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomedical_Engineering">Biomedical Engineering</a>, <script data-card-contents-for-ri="1131" type="text/json">{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4392" rel="nofollow" href="https://www.academia.edu/Documents/in/Monte_Carlo_Simulation">Monte Carlo Simulation</a>, <script data-card-contents-for-ri="4392" type="text/json">{"id":4392,"name":"Monte Carlo Simulation","url":"https://www.academia.edu/Documents/in/Monte_Carlo_Simulation?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="4987" rel="nofollow" href="https://www.academia.edu/Documents/in/Kinetics">Kinetics</a>, <script data-card-contents-for-ri="4987" type="text/json">{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a><script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=48366239]'), work: {"id":48366239,"title":"Consequences of using a simplified kinetic model for dynamic PET data","created_at":"2021-05-04T15:28:29.955-07:00","url":"https://www.academia.edu/48366239/Consequences_of_using_a_simplified_kinetic_model_for_dynamic_PET_data?f_ri=10035","dom_id":"work_48366239","summary":"We compared a physiological model of 82Rb kinetics in the myocardium with two reduced-order models to determine their usefulness in assessing physiological parameters from dynamic PET data. A three-compartment model of 82Rb in the myocardium was used to simulate kinetic PET ROI data. Simulations were generated for eight different blood-flow rates reflecting the physiological range of interest. Two reduced-order models commonly used with myocardial PET studies were fit to the simulated data, and parameters of the reduced-order models were compared with the physiological parameters. Then all three models were fit to the simulated data with noise added. Monte Carlo simulations were used to evaluate and compare the diagnostic utility of the reduced-order models. A description length criterion was used to assess goodness of fit for each model. Finally, fits to simulated data were compared with fits to actual dynamic PET data. Fits of the reduced-order models to the three-compartment mode...","downloadable_attachments":[{"id":67026551,"asset_id":48366239,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":39554629,"first_name":"L.","last_name":"Borland","domain_name":"independent","page_name":"LBorland","display_name":"L. Borland","profile_url":"https://independent.academia.edu/LBorland?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=10035","nofollow":true},{"id":4392,"name":"Monte Carlo Simulation","url":"https://www.academia.edu/Documents/in/Monte_Carlo_Simulation?f_ri=10035","nofollow":true},{"id":4987,"name":"Kinetics","url":"https://www.academia.edu/Documents/in/Kinetics?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":11111,"name":"Pharmacokinetics","url":"https://www.academia.edu/Documents/in/Pharmacokinetics?f_ri=10035"},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=10035"},{"id":39920,"name":"Parameter estimation","url":"https://www.academia.edu/Documents/in/Parameter_estimation?f_ri=10035"},{"id":52438,"name":"Dogs","url":"https://www.academia.edu/Documents/in/Dogs?f_ri=10035"},{"id":93174,"name":"Goodness of Fit","url":"https://www.academia.edu/Documents/in/Goodness_of_Fit?f_ri=10035"},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":426588,"name":"Blood Flow","url":"https://www.academia.edu/Documents/in/Blood_Flow?f_ri=10035"},{"id":442575,"name":"Fitting","url":"https://www.academia.edu/Documents/in/Fitting?f_ri=10035"},{"id":618800,"name":"Coronary Circulation","url":"https://www.academia.edu/Documents/in/Coronary_Circulation?f_ri=10035"},{"id":1333436,"name":"Monte Carlo Method","url":"https://www.academia.edu/Documents/in/Monte_Carlo_Method?f_ri=10035"},{"id":3115840,"name":"Myocardial Blood Flow","url":"https://www.academia.edu/Documents/in/Myocardial_Blood_Flow?f_ri=10035"},{"id":3476481,"name":"Compartment Model","url":"https://www.academia.edu/Documents/in/Compartment_Model?f_ri=10035"},{"id":3849021,"name":"Kinetic model","url":"https://www.academia.edu/Documents/in/Kinetic_model?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_34404308" data-work_id="34404308" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/34404308/Ventilation_perfusion_lung_scanning_in_the_evaluation_of_pulmonary_hypertension">Ventilation-perfusion lung scanning in the evaluation of pulmonary hypertension</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The objective of this study was to define the sensitivity, specificity and accuracy of ventilation-perfusion (V/Q) lung scanning in distinguishing chronic thromboembolic pulmonary hypertension (PHT) from other nonembolic causes of PHT.... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_34404308" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The objective of this study was to define the sensitivity, specificity and accuracy of ventilation-perfusion (V/Q) lung scanning in distinguishing chronic thromboembolic pulmonary hypertension (PHT) from other nonembolic causes of PHT. The V/Q lung scans from 75 patients in whom a confirmed cause of PHT was established were retrospectively reviewed. Twenty-five patients (33%) had chronic thromboembolic PHT, whereas 35 patients (47%) and 15 patients (20%) suffered from primary PHT and secondary nonthromboembolic PHT, respectively. A high-probability V/Q scan interpretation had a sensitivity of 96% and a specificity of 94% for detecting patients with thromboembolic PHT. The combination of high- and intermediate-probability V/Q scan interpretations had a sensitivity of 100% for detecting patients with thromboembolic PH; however, the specificity decreased to 86%. Of the 35 patients with primary PHT, all but one patient had low-probability V/Q scan interpretations. In this series, a low-...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/34404308" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f4b157f56c45da69e2dcb58fbf57176d" rel="nofollow" data-download="{"attachment_id":54285658,"asset_id":34404308,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/54285658/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="35075800" href="https://independent.academia.edu/AbassAlavi">Abass Alavi</a><script data-card-contents-for-user="35075800" type="text/json">{"id":35075800,"first_name":"Abass","last_name":"Alavi","domain_name":"independent","page_name":"AbassAlavi","display_name":"Abass Alavi","profile_url":"https://independent.academia.edu/AbassAlavi?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_34404308 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="34404308"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 34404308, container: ".js-paper-rank-work_34404308", }); });</script></li><li class="js-percentile-work_34404308 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 34404308; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_34404308"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_34404308 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="34404308"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 34404308; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=34404308]").text(description); $(".js-view-count-work_34404308").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_34404308").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="34404308"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="22506" rel="nofollow" href="https://www.academia.edu/Documents/in/Adolescent">Adolescent</a>, <script data-card-contents-for-ri="22506" type="text/json">{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="31958" rel="nofollow" href="https://www.academia.edu/Documents/in/Pulmonary_Hypertension">Pulmonary Hypertension</a>, <script data-card-contents-for-ri="31958" type="text/json">{"id":31958,"name":"Pulmonary Hypertension","url":"https://www.academia.edu/Documents/in/Pulmonary_Hypertension?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="71308" rel="nofollow" href="https://www.academia.edu/Documents/in/Pulmonary_fibrosis">Pulmonary fibrosis</a><script data-card-contents-for-ri="71308" type="text/json">{"id":71308,"name":"Pulmonary fibrosis","url":"https://www.academia.edu/Documents/in/Pulmonary_fibrosis?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=34404308]'), work: {"id":34404308,"title":"Ventilation-perfusion lung scanning in the evaluation of pulmonary hypertension","created_at":"2017-08-29T18:52:30.812-07:00","url":"https://www.academia.edu/34404308/Ventilation_perfusion_lung_scanning_in_the_evaluation_of_pulmonary_hypertension?f_ri=10035","dom_id":"work_34404308","summary":"The objective of this study was to define the sensitivity, specificity and accuracy of ventilation-perfusion (V/Q) lung scanning in distinguishing chronic thromboembolic pulmonary hypertension (PHT) from other nonembolic causes of PHT. The V/Q lung scans from 75 patients in whom a confirmed cause of PHT was established were retrospectively reviewed. Twenty-five patients (33%) had chronic thromboembolic PHT, whereas 35 patients (47%) and 15 patients (20%) suffered from primary PHT and secondary nonthromboembolic PHT, respectively. A high-probability V/Q scan interpretation had a sensitivity of 96% and a specificity of 94% for detecting patients with thromboembolic PHT. The combination of high- and intermediate-probability V/Q scan interpretations had a sensitivity of 100% for detecting patients with thromboembolic PH; however, the specificity decreased to 86%. Of the 35 patients with primary PHT, all but one patient had low-probability V/Q scan interpretations. In this series, a low-...","downloadable_attachments":[{"id":54285658,"asset_id":34404308,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":35075800,"first_name":"Abass","last_name":"Alavi","domain_name":"independent","page_name":"AbassAlavi","display_name":"Abass Alavi","profile_url":"https://independent.academia.edu/AbassAlavi?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=10035","nofollow":true},{"id":31958,"name":"Pulmonary Hypertension","url":"https://www.academia.edu/Documents/in/Pulmonary_Hypertension?f_ri=10035","nofollow":true},{"id":71308,"name":"Pulmonary fibrosis","url":"https://www.academia.edu/Documents/in/Pulmonary_fibrosis?f_ri=10035","nofollow":true},{"id":97269,"name":"Chronic Disease","url":"https://www.academia.edu/Documents/in/Chronic_Disease?f_ri=10035"},{"id":102587,"name":"Pulmonary Embolism","url":"https://www.academia.edu/Documents/in/Pulmonary_Embolism?f_ri=10035"},{"id":176423,"name":"Thromboembolism","url":"https://www.academia.edu/Documents/in/Thromboembolism?f_ri=10035"},{"id":197297,"name":"Lung","url":"https://www.academia.edu/Documents/in/Lung?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=10035"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=10035"},{"id":2226523,"name":"Pulmonary circulation","url":"https://www.academia.edu/Documents/in/Pulmonary_circulation?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_33267721" data-work_id="33267721" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/33267721/Prognostic_value_of_myocardial_perfusion_and_ventricular_function_in_a_Japanese_multicenter_cohort_study_J_ACCESS_the_first_year_total_events_and_hard_events">Prognostic value of myocardial perfusion and ventricular function in a Japanese multicenter cohort study (J-ACCESS): the first-year total events and hard events</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest">Objective To determine the prognostic value of myocardial ischemia, function and coronary risk factors on total and hard cardiac events using myocardial perfusion imaging in a Japanese population.</div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/33267721" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="809adcc26fedc1b41388f625a45bfd91" rel="nofollow" data-download="{"attachment_id":53336481,"asset_id":33267721,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/53336481/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="33148106" href="https://kanazawa-u.academia.edu/KenichiNakajima">Kenichi Nakajima</a><script data-card-contents-for-user="33148106" type="text/json">{"id":33148106,"first_name":"Kenichi","last_name":"Nakajima","domain_name":"kanazawa-u","page_name":"KenichiNakajima","display_name":"Kenichi Nakajima","profile_url":"https://kanazawa-u.academia.edu/KenichiNakajima?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_33267721 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="33267721"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 33267721, container: ".js-paper-rank-work_33267721", }); });</script></li><li class="js-percentile-work_33267721 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 33267721; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_33267721"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_33267721 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="33267721"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 33267721; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=33267721]").text(description); $(".js-view-count-work_33267721").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_33267721").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="33267721"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">25</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="606" rel="nofollow" href="https://www.academia.edu/Documents/in/Cardiology">Cardiology</a>, <script data-card-contents-for-ri="606" type="text/json">{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="17158" rel="nofollow" href="https://www.academia.edu/Documents/in/Japan">Japan</a>, <script data-card-contents-for-ri="17158" type="text/json">{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="41482" rel="nofollow" href="https://www.academia.edu/Documents/in/Multivariate_Analysis">Multivariate Analysis</a><script data-card-contents-for-ri="41482" type="text/json">{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=33267721]'), work: {"id":33267721,"title":"Prognostic value of myocardial perfusion and ventricular function in a Japanese multicenter cohort study (J-ACCESS): the first-year total events and hard events","created_at":"2017-05-30T17:16:35.720-07:00","url":"https://www.academia.edu/33267721/Prognostic_value_of_myocardial_perfusion_and_ventricular_function_in_a_Japanese_multicenter_cohort_study_J_ACCESS_the_first_year_total_events_and_hard_events?f_ri=10035","dom_id":"work_33267721","summary":"Objective To determine the prognostic value of myocardial ischemia, function and coronary risk factors on total and hard cardiac events using myocardial perfusion imaging in a Japanese population.","downloadable_attachments":[{"id":53336481,"asset_id":33267721,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":33148106,"first_name":"Kenichi","last_name":"Nakajima","domain_name":"kanazawa-u","page_name":"KenichiNakajima","display_name":"Kenichi Nakajima","profile_url":"https://kanazawa-u.academia.edu/KenichiNakajima?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":606,"name":"Cardiology","url":"https://www.academia.edu/Documents/in/Cardiology?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":17158,"name":"Japan","url":"https://www.academia.edu/Documents/in/Japan?f_ri=10035","nofollow":true},{"id":41482,"name":"Multivariate Analysis","url":"https://www.academia.edu/Documents/in/Multivariate_Analysis?f_ri=10035","nofollow":true},{"id":49633,"name":"Heart Failure","url":"https://www.academia.edu/Documents/in/Heart_Failure?f_ri=10035"},{"id":123230,"name":"Regression Analysis","url":"https://www.academia.edu/Documents/in/Regression_Analysis?f_ri=10035"},{"id":131185,"name":"Cohort Study","url":"https://www.academia.edu/Documents/in/Cohort_Study?f_ri=10035"},{"id":137516,"name":"Follow-up studies","url":"https://www.academia.edu/Documents/in/Follow-up_studies?f_ri=10035"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=10035"},{"id":442734,"name":"First Year","url":"https://www.academia.edu/Documents/in/First_Year?f_ri=10035"},{"id":479871,"name":"Angina pectoris","url":"https://www.academia.edu/Documents/in/Angina_pectoris?f_ri=10035"},{"id":489727,"name":"Prognosis","url":"https://www.academia.edu/Documents/in/Prognosis?f_ri=10035"},{"id":493010,"name":"Sudden Cardiac Death","url":"https://www.academia.edu/Documents/in/Sudden_Cardiac_Death?f_ri=10035"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=10035"},{"id":659547,"name":"Ischemic Heart Disease","url":"https://www.academia.edu/Documents/in/Ischemic_Heart_Disease?f_ri=10035"},{"id":784087,"name":"Myocardial Perfusion Imaging","url":"https://www.academia.edu/Documents/in/Myocardial_Perfusion_Imaging?f_ri=10035"},{"id":878419,"name":"Ejection Fraction","url":"https://www.academia.edu/Documents/in/Ejection_Fraction?f_ri=10035"},{"id":1647706,"name":"Unstable Angina","url":"https://www.academia.edu/Documents/in/Unstable_Angina?f_ri=10035"},{"id":1819400,"name":"Cohort Studies","url":"https://www.academia.edu/Documents/in/Cohort_Studies?f_ri=10035"},{"id":2005416,"name":"Coronary Risk Factors","url":"https://www.academia.edu/Documents/in/Coronary_Risk_Factors?f_ri=10035"},{"id":2503388,"name":"Myocardial Ischemia","url":"https://www.academia.edu/Documents/in/Myocardial_Ischemia?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_29875932" data-work_id="29875932" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/29875932/Evaluation_of_the_genotoxic_effects_of_chronic_low_dose_ionizing_radiation_exposure_on_nuclear_medicine_workers">Evaluation of the genotoxic effects of chronic low-dose ionizing radiation exposure on nuclear medicine workers</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Nuclear medicine workers are occupationally exposed to chronic ionizing radiation. It is known that ionizing radiation may have damaging effects on chromosomes. In the present study, we investigated the genotoxic effects of ionizing... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_29875932" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Nuclear medicine workers are occupationally exposed to chronic ionizing radiation. It is known that ionizing radiation may have damaging effects on chromosomes. In the present study, we investigated the genotoxic effects of ionizing radiation on nuclear medicine workers. We used two different indicators of genotoxicity methods: sister chromatid exchange (SCE) and micronucleus (MN).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/29875932" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="2e9e8a150ad4f360629b703e8906a872" rel="nofollow" data-download="{"attachment_id":50343367,"asset_id":29875932,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/50343367/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="56725058" href="https://suleyman-demirel.academia.edu/SitkiOztas">Sitki Oztas</a><script data-card-contents-for-user="56725058" type="text/json">{"id":56725058,"first_name":"Sitki","last_name":"Oztas","domain_name":"suleyman-demirel","page_name":"SitkiOztas","display_name":"Sitki Oztas","profile_url":"https://suleyman-demirel.academia.edu/SitkiOztas?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_29875932 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="29875932"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 29875932, container: ".js-paper-rank-work_29875932", }); 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It is known that ionizing radiation may have damaging effects on chromosomes. In the present study, we investigated the genotoxic effects of ionizing radiation on nuclear medicine workers. We used two different indicators of genotoxicity methods: sister chromatid exchange (SCE) and micronucleus (MN).","downloadable_attachments":[{"id":50343367,"asset_id":29875932,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":56725058,"first_name":"Sitki","last_name":"Oztas","domain_name":"suleyman-demirel","page_name":"SitkiOztas","display_name":"Sitki Oztas","profile_url":"https://suleyman-demirel.academia.edu/SitkiOztas?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":72821,"name":"Low Dose","url":"https://www.academia.edu/Documents/in/Low_Dose?f_ri=10035","nofollow":true},{"id":99282,"name":"Holidays","url":"https://www.academia.edu/Documents/in/Holidays?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":295245,"name":"Micronucleus","url":"https://www.academia.edu/Documents/in/Micronucleus?f_ri=10035"},{"id":396914,"name":"Occupational Exposure","url":"https://www.academia.edu/Documents/in/Occupational_Exposure?f_ri=10035"},{"id":413195,"name":"Time Factors","url":"https://www.academia.edu/Documents/in/Time_Factors?f_ri=10035"},{"id":764258,"name":"Ionizing Radiation","url":"https://www.academia.edu/Documents/in/Ionizing_Radiation?f_ri=10035"},{"id":868560,"name":"Lymphocytes","url":"https://www.academia.edu/Documents/in/Lymphocytes?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8656574" data-work_id="8656574" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8656574/Infrared_spectra_of_new_Re_III_complexes_with_thiourea_derivatives">Infrared spectra of new Re(III) complexes with thiourea derivatives</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Complexes of the type [Re III L 6 ]X 3 , with L0/thiourea, N -methylthiourea, N -ethylthiourea or N ,N ?-dimethytlthiourea and X 0/Cl ( or PF 6 ( , were prepared as suitable precursors for the synthesis of new rhenium complexes... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8656574" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Complexes of the type [Re III L 6 ]X 3 , with L0/thiourea, N -methylthiourea, N -ethylthiourea or N ,N ?-dimethytlthiourea and X 0/Cl ( or PF 6 ( , were prepared as suitable precursors for the synthesis of new rhenium complexes potentially useful in nuclear medicine. The infrared (IR) spectra of these complexes were recorded and analyzed and a general vibrational pattern for Re(III) complexes with thiourea derivatives could be established. Approximate assignments for N -allylthiourea and N -ethylthiourea are also proposed for the first time. The synthesis of the new complex [Re III (N -allylthiourea) 6 ](PF 6 ) 3 is also reported, and information about its structural characteristics was obtained comparing its IR spectrum with those of the other complexes of the investigated series. #</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/8656574" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b746bb18bfcdd839cdc4f57bedbb05e6" rel="nofollow" data-download="{"attachment_id":48029418,"asset_id":8656574,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/48029418/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="18067201" href="https://independent.academia.edu/DinorahGambino">Dinorah Gambino</a><script data-card-contents-for-user="18067201" type="text/json">{"id":18067201,"first_name":"Dinorah","last_name":"Gambino","domain_name":"independent","page_name":"DinorahGambino","display_name":"Dinorah Gambino","profile_url":"https://independent.academia.edu/DinorahGambino?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_8656574 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="8656574"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 8656574, container: ".js-paper-rank-work_8656574", }); 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The infrared (IR) spectra of these complexes were recorded and analyzed and a general vibrational pattern for Re(III) complexes with thiourea derivatives could be established. Approximate assignments for N -allylthiourea and N -ethylthiourea are also proposed for the first time. The synthesis of the new complex [Re III (N -allylthiourea) 6 ](PF 6 ) 3 is also reported, and information about its structural characteristics was obtained comparing its IR spectrum with those of the other complexes of the investigated series. #","downloadable_attachments":[{"id":48029418,"asset_id":8656574,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":18067201,"first_name":"Dinorah","last_name":"Gambino","domain_name":"independent","page_name":"DinorahGambino","display_name":"Dinorah Gambino","profile_url":"https://independent.academia.edu/DinorahGambino?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":524,"name":"Analytical Chemistry","url":"https://www.academia.edu/Documents/in/Analytical_Chemistry?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":78842,"name":"Infrared spectroscopy","url":"https://www.academia.edu/Documents/in/Infrared_spectroscopy?f_ri=10035","nofollow":true},{"id":121912,"name":"Rhenium","url":"https://www.academia.edu/Documents/in/Rhenium?f_ri=10035","nofollow":true},{"id":229148,"name":"Thiourea","url":"https://www.academia.edu/Documents/in/Thiourea?f_ri=10035"},{"id":321836,"name":"Spectrum","url":"https://www.academia.edu/Documents/in/Spectrum?f_ri=10035"},{"id":335361,"name":"Infrared","url":"https://www.academia.edu/Documents/in/Infrared?f_ri=10035"},{"id":420706,"name":"Infrared spectra","url":"https://www.academia.edu/Documents/in/Infrared_spectra?f_ri=10035"},{"id":967378,"name":"Radioisotopes","url":"https://www.academia.edu/Documents/in/Radioisotopes?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_9152851" data-work_id="9152851" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div 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href="https://www.academia.edu/23142692/The_new_EANM_paediatric_dosage_card_additional_notes_with_respect_to_F_18">The new EANM paediatric dosage card: additional notes with respect to F-18</a></div></div><div class="u-pb4x u-mt3x"></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23142692" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="dc45935affa691a439e98cf285580b19" rel="nofollow" data-download="{"attachment_id":43630731,"asset_id":23142692,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm 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Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":335365,"name":"Radiometry","url":"https://www.academia.edu/Documents/in/Radiometry?f_ri=10035"},{"id":394423,"name":"Radionuclide","url":"https://www.academia.edu/Documents/in/Radionuclide?f_ri=10035"},{"id":599005,"name":"Dosimetry","url":"https://www.academia.edu/Documents/in/Dosimetry?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_19821303 coauthored" data-work_id="19821303" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/19821303/Scintigraphic_Assessment_of_Patellar_Viability_in_Total_Knee_Arthroplasty_After_Lateral_Release">Scintigraphic Assessment of Patellar Viability in Total Knee Arthroplasty After Lateral Release</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">To what extent lateral retinacular release done in total knee arthroplasty compromises patellar viability has been debated. This study is a prospective study to assess patellar viability using Technetium-99m methylene diphosphate (Tc-99m... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_19821303" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To what extent lateral retinacular release done in total knee arthroplasty compromises patellar viability has been debated. This study is a prospective study to assess patellar viability using Technetium-99m methylene diphosphate (Tc-99m MDP) scintigraphy. Between 2005 and 2006, 59 patients (72 knees) who underwent primary total knee arthroplasty were studied, of which 36 required lateral release. All patients underwent regional bone scan using Tc-99m MDP before and 1 to 3 weeks after the surgery. Two nuclear medicine consultants using both qualitative and quantitative assessment interpreted the scans independently. Fourteen knees with lateral release showed scintigraphic signs of hypovascularity in the early postoperative period that normalized in 8-week postoperative period. This study documents the greater incidence of transient patellar hypovascularity associated with lateral release.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/19821303" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="b46fc9220fbfde61a1a51df586484885" rel="nofollow" data-download="{"attachment_id":40863123,"asset_id":19821303,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/40863123/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="40579911" href="https://independent.academia.edu/UdayPawar">Uday Pawar</a><script data-card-contents-for-user="40579911" type="text/json">{"id":40579911,"first_name":"Uday","last_name":"Pawar","domain_name":"independent","page_name":"UdayPawar","display_name":"Uday Pawar","profile_url":"https://independent.academia.edu/UdayPawar?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span><span class="u-displayInlineBlock InlineList-item-text"> and <span class="u-textDecorationUnderline u-clickable InlineList-item-text js-work-more-authors-19821303">+1</span><div class="hidden js-additional-users-19821303"><div><span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a href="https://aimhospital.academia.edu/JaiThilak">Jai Thilak</a></span></div></div></span><script>(function(){ var popoverSettings = { el: $('.js-work-more-authors-19821303'), placement: 'bottom', hide_delay: 200, html: true, content: function(){ return $('.js-additional-users-19821303').html(); } } new HoverPopover(popoverSettings); })();</script></li><li class="js-paper-rank-work_19821303 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="19821303"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 19821303, container: ".js-paper-rank-work_19821303", }); });</script></li><li class="js-percentile-work_19821303 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 19821303; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_19821303"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_19821303 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="19821303"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 19821303; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=19821303]").text(description); $(".js-view-count-work_19821303").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_19821303").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="19821303"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">18</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="1131" rel="nofollow" href="https://www.academia.edu/Documents/in/Biomedical_Engineering">Biomedical Engineering</a>, <script data-card-contents-for-ri="1131" type="text/json">{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12426" rel="nofollow" href="https://www.academia.edu/Documents/in/Treatment_Outcome">Treatment Outcome</a>, <script data-card-contents-for-ri="12426" type="text/json">{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="12733" rel="nofollow" href="https://www.academia.edu/Documents/in/Rheumatoid_Arthritis">Rheumatoid Arthritis</a><script data-card-contents-for-ri="12733" type="text/json">{"id":12733,"name":"Rheumatoid Arthritis","url":"https://www.academia.edu/Documents/in/Rheumatoid_Arthritis?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=19821303]'), work: {"id":19821303,"title":"Scintigraphic Assessment of Patellar Viability in Total Knee Arthroplasty After Lateral Release","created_at":"2015-12-24T16:18:49.509-08:00","url":"https://www.academia.edu/19821303/Scintigraphic_Assessment_of_Patellar_Viability_in_Total_Knee_Arthroplasty_After_Lateral_Release?f_ri=10035","dom_id":"work_19821303","summary":"To what extent lateral retinacular release done in total knee arthroplasty compromises patellar viability has been debated. This study is a prospective study to assess patellar viability using Technetium-99m methylene diphosphate (Tc-99m MDP) scintigraphy. Between 2005 and 2006, 59 patients (72 knees) who underwent primary total knee arthroplasty were studied, of which 36 required lateral release. All patients underwent regional bone scan using Tc-99m MDP before and 1 to 3 weeks after the surgery. Two nuclear medicine consultants using both qualitative and quantitative assessment interpreted the scans independently. Fourteen knees with lateral release showed scintigraphic signs of hypovascularity in the early postoperative period that normalized in 8-week postoperative period. This study documents the greater incidence of transient patellar hypovascularity associated with lateral release.","downloadable_attachments":[{"id":40863123,"asset_id":19821303,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":40579911,"first_name":"Uday","last_name":"Pawar","domain_name":"independent","page_name":"UdayPawar","display_name":"Uday Pawar","profile_url":"https://independent.academia.edu/UdayPawar?f_ri=10035","photo":"/images/s65_no_pic.png"},{"id":40719657,"first_name":"Jai","last_name":"Thilak","domain_name":"aimhospital","page_name":"JaiThilak","display_name":"Jai Thilak","profile_url":"https://aimhospital.academia.edu/JaiThilak?f_ri=10035","photo":"https://0.academia-photos.com/40719657/11088578/12374300/s65_jai.thilak.jpg"}],"research_interests":[{"id":1131,"name":"Biomedical Engineering","url":"https://www.academia.edu/Documents/in/Biomedical_Engineering?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":12426,"name":"Treatment Outcome","url":"https://www.academia.edu/Documents/in/Treatment_Outcome?f_ri=10035","nofollow":true},{"id":12733,"name":"Rheumatoid Arthritis","url":"https://www.academia.edu/Documents/in/Rheumatoid_Arthritis?f_ri=10035","nofollow":true},{"id":62112,"name":"Prospective studies","url":"https://www.academia.edu/Documents/in/Prospective_studies?f_ri=10035"},{"id":82983,"name":"Ischemia","url":"https://www.academia.edu/Documents/in/Ischemia?f_ri=10035"},{"id":161176,"name":"The","url":"https://www.academia.edu/Documents/in/The?f_ri=10035"},{"id":173135,"name":"Radionuclide imaging","url":"https://www.academia.edu/Documents/in/Radionuclide_imaging?f_ri=10035"},{"id":192721,"name":"Risk factors","url":"https://www.academia.edu/Documents/in/Risk_factors?f_ri=10035"},{"id":206309,"name":"Arthroplasty","url":"https://www.academia.edu/Documents/in/Arthroplasty?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":457463,"name":"Knee Osteoarthritis","url":"https://www.academia.edu/Documents/in/Knee_Osteoarthritis?f_ri=10035"},{"id":620049,"name":"Risk Factors","url":"https://www.academia.edu/Documents/in/Risk_Factors-1?f_ri=10035"},{"id":1145265,"name":"Knee Joint","url":"https://www.academia.edu/Documents/in/Knee_Joint?f_ri=10035"},{"id":1312754,"name":"Prospective Study","url":"https://www.academia.edu/Documents/in/Prospective_Study?f_ri=10035"},{"id":1772577,"name":"Osteonecrosis","url":"https://www.academia.edu/Documents/in/Osteonecrosis?f_ri=10035"},{"id":1953423,"name":"Postoperative Period","url":"https://www.academia.edu/Documents/in/Postoperative_Period?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_17598961" data-work_id="17598961" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/17598961/Dynamic_heart_phantom_for_the_quality_control_of_SPECT_equipment">Dynamic heart phantom for the quality control of SPECT equipment</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A nuclear imaging of heart is a noninvasive procedure that reveals the cardiac structure and physiology enabling evaluation of cardiac function. According to the regulations published by the Polish Government and the Polish Ministry of... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_17598961" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A nuclear imaging of heart is a noninvasive procedure that reveals the cardiac structure and physiology enabling evaluation of cardiac function. According to the regulations published by the Polish Government and the Polish Ministry of Health, the nuclear medicine departments must follow the new legislation which has imposed quality assurance (QA) and quality control (QC) of equipment and medical testing procedures as compulsory.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/17598961" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e06c7dd03c5a6da592a90c9ced22994b" rel="nofollow" data-download="{"attachment_id":39604872,"asset_id":17598961,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/39604872/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="37436348" href="https://independent.academia.edu/MartaWasilewskaradwanska">Marta Wasilewska-radwanska</a><script data-card-contents-for-user="37436348" type="text/json">{"id":37436348,"first_name":"Marta","last_name":"Wasilewska-radwanska","domain_name":"independent","page_name":"MartaWasilewskaradwanska","display_name":"Marta Wasilewska-radwanska","profile_url":"https://independent.academia.edu/MartaWasilewskaradwanska?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_17598961 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="17598961"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 17598961, container: ".js-paper-rank-work_17598961", }); });</script></li><li class="js-percentile-work_17598961 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 17598961; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_17598961"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_17598961 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="17598961"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 17598961; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=17598961]").text(description); $(".js-view-count-work_17598961").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_17598961").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="17598961"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">13</a>  </div><span class="InlineList-item-text u-textTruncate u-pl10x"><a class="InlineList-item-text" data-has-card-for-ri="502" rel="nofollow" href="https://www.academia.edu/Documents/in/Biophysics">Biophysics</a>, <script data-card-contents-for-ri="502" type="text/json">{"id":502,"name":"Biophysics","url":"https://www.academia.edu/Documents/in/Biophysics?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="37306" rel="nofollow" href="https://www.academia.edu/Documents/in/Quality_Control">Quality Control</a>, <script data-card-contents-for-ri="37306" type="text/json">{"id":37306,"name":"Quality Control","url":"https://www.academia.edu/Documents/in/Quality_Control?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="47884" rel="nofollow" href="https://www.academia.edu/Documents/in/Biological_Sciences">Biological Sciences</a><script data-card-contents-for-ri="47884" type="text/json">{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=17598961]'), work: {"id":17598961,"title":"Dynamic heart phantom for the quality control of SPECT equipment","created_at":"2015-11-02T01:03:20.273-08:00","url":"https://www.academia.edu/17598961/Dynamic_heart_phantom_for_the_quality_control_of_SPECT_equipment?f_ri=10035","dom_id":"work_17598961","summary":"A nuclear imaging of heart is a noninvasive procedure that reveals the cardiac structure and physiology enabling evaluation of cardiac function. According to the regulations published by the Polish Government and the Polish Ministry of Health, the nuclear medicine departments must follow the new legislation which has imposed quality assurance (QA) and quality control (QC) of equipment and medical testing procedures as compulsory.","downloadable_attachments":[{"id":39604872,"asset_id":17598961,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":37436348,"first_name":"Marta","last_name":"Wasilewska-radwanska","domain_name":"independent","page_name":"MartaWasilewskaradwanska","display_name":"Marta Wasilewska-radwanska","profile_url":"https://independent.academia.edu/MartaWasilewskaradwanska?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":502,"name":"Biophysics","url":"https://www.academia.edu/Documents/in/Biophysics?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":37306,"name":"Quality Control","url":"https://www.academia.edu/Documents/in/Quality_Control?f_ri=10035","nofollow":true},{"id":47884,"name":"Biological Sciences","url":"https://www.academia.edu/Documents/in/Biological_Sciences?f_ri=10035","nofollow":true},{"id":59918,"name":"Quality Assurance","url":"https://www.academia.edu/Documents/in/Quality_Assurance?f_ri=10035"},{"id":88815,"name":"Legislation","url":"https://www.academia.edu/Documents/in/Legislation?f_ri=10035"},{"id":118582,"name":"Physical sciences","url":"https://www.academia.edu/Documents/in/Physical_sciences?f_ri=10035"},{"id":131495,"name":"Heart","url":"https://www.academia.edu/Documents/in/Heart?f_ri=10035"},{"id":329268,"name":"Medical Image","url":"https://www.academia.edu/Documents/in/Medical_Image?f_ri=10035"},{"id":375439,"name":"Single Photon Emission Computed Tomography","url":"https://www.academia.edu/Documents/in/Single_Photon_Emission_Computed_Tomography?f_ri=10035"},{"id":764258,"name":"Ionizing Radiation","url":"https://www.academia.edu/Documents/in/Ionizing_Radiation?f_ri=10035"},{"id":1329451,"name":"Ministry of Health","url":"https://www.academia.edu/Documents/in/Ministry_of_Health?f_ri=10035"},{"id":1572218,"name":"Left Ventricle","url":"https://www.academia.edu/Documents/in/Left_Ventricle?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_69030749" data-work_id="69030749" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/69030749/Small_animal_PET_imaging_of_pancreatic_cancer_xenografts_using_64Cu_labeled_monoclonal_antibody_MAb159">Small animal PET imaging of pancreatic cancer xenografts using 64Cu labeled monoclonal antibody MAb159</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">The overexpression of the GRP78 receptor on cell surface has been linked with the tumor growth, metastasis, and resistance to therapy. Based on a novel anti-GRP78 monoclonal antibody (MAb159), we developed a (64)Cu-labeled probe for... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_69030749" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">The overexpression of the GRP78 receptor on cell surface has been linked with the tumor growth, metastasis, and resistance to therapy. Based on a novel anti-GRP78 monoclonal antibody (MAb159), we developed a (64)Cu-labeled probe for positron emission tomography (PET) imaging of tumor GRP78 expression. MAb159 was conjugated with the (64)Cu-chelator DOTA through lysine&#39;s on the antibody. DOTA-hIgG was also prepared as a control, which did not bind to GRP78. The resulting PET probes were evaluated in BxPC-3 pancreatic cancer xenografts in athymic nude mice. The radiotracer was synthesized with a specific activity of 0.8MBq/µg antibody. In BxPC3 xenografts, (64)Cu-DOTA-MAb159 demonstrated prominent tumor accumulation (4.3 ± 1.2, 15.4 ± 2.6, and 18.3 ± 1.0%ID/g at 1, 17, and 48 post injection, respectively). In contrast, (64)Cu-DOTA-hIgG had low BxPC3 tumor accumulation (4.8 ± 0.5, 7.5 ± 0.7, and 4.6 ± 0.8ID/g at 1, 17, and 48 h post injection, respectively). We have demonstrated tha...</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/69030749" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="31c2a72788636e5c2fda0aebda210539" rel="nofollow" data-download="{"attachment_id":79286148,"asset_id":69030749,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/79286148/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="197100137" href="https://independent.academia.edu/ValeryKrasnoperov">Valery Krasnoperov</a><script data-card-contents-for-user="197100137" type="text/json">{"id":197100137,"first_name":"Valery","last_name":"Krasnoperov","domain_name":"independent","page_name":"ValeryKrasnoperov","display_name":"Valery Krasnoperov","profile_url":"https://independent.academia.edu/ValeryKrasnoperov?f_ri=10035","photo":"https://0.academia-photos.com/197100137/59254373/47496821/s65_valery.krasnoperov.png"}</script></span></span></li><li class="js-paper-rank-work_69030749 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="69030749"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 69030749, container: ".js-paper-rank-work_69030749", }); 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Based on a novel anti-GRP78 monoclonal antibody (MAb159), we developed a (64)Cu-labeled probe for positron emission tomography (PET) imaging of tumor GRP78 expression. MAb159 was conjugated with the (64)Cu-chelator DOTA through lysine\u0026#39;s on the antibody. DOTA-hIgG was also prepared as a control, which did not bind to GRP78. The resulting PET probes were evaluated in BxPC-3 pancreatic cancer xenografts in athymic nude mice. The radiotracer was synthesized with a specific activity of 0.8MBq/µg antibody. In BxPC3 xenografts, (64)Cu-DOTA-MAb159 demonstrated prominent tumor accumulation (4.3 ± 1.2, 15.4 ± 2.6, and 18.3 ± 1.0%ID/g at 1, 17, and 48 post injection, respectively). In contrast, (64)Cu-DOTA-hIgG had low BxPC3 tumor accumulation (4.8 ± 0.5, 7.5 ± 0.7, and 4.6 ± 0.8ID/g at 1, 17, and 48 h post injection, respectively). We have demonstrated tha...","downloadable_attachments":[{"id":79286148,"asset_id":69030749,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":197100137,"first_name":"Valery","last_name":"Krasnoperov","domain_name":"independent","page_name":"ValeryKrasnoperov","display_name":"Valery Krasnoperov","profile_url":"https://independent.academia.edu/ValeryKrasnoperov?f_ri=10035","photo":"https://0.academia-photos.com/197100137/59254373/47496821/s65_valery.krasnoperov.png"}],"research_interests":[{"id":7700,"name":"Fluorescence Microscopy","url":"https://www.academia.edu/Documents/in/Fluorescence_Microscopy?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true},{"id":84760,"name":"Mice","url":"https://www.academia.edu/Documents/in/Mice?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":588751,"name":"Heat Shock Proteins","url":"https://www.academia.edu/Documents/in/Heat_Shock_Proteins?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"},{"id":1716403,"name":"immunoglobulin G","url":"https://www.academia.edu/Documents/in/immunoglobulin_G?f_ri=10035"},{"id":2950651,"name":"Tissue distribution","url":"https://www.academia.edu/Documents/in/Tissue_distribution?f_ri=10035"},{"id":3521397,"name":"Pancreatic neoplasms","url":"https://www.academia.edu/Documents/in/Pancreatic_neoplasms?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_60015210" data-work_id="60015210" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/60015210/Limitation_of_the_long_lived_121Te_contaminant_in_production_of_123I_through_the_124Xe_p_x_route">Limitation of the long-lived 121Te contaminant in production of 123I through the 124Xe(p,x) route</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">production 121 I-121 Te contamination 122 Xe and 120m,g;119 I isotopes 124 Xe gas cells Cross sections Nuclear model calculations a b s t r a c t The 13.2 h half-life radioisotope 123 I is widely used in clinical nuclear medicine... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_60015210" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">production 121 I-121 Te contamination 122 Xe and 120m,g;119 I isotopes 124 Xe gas cells Cross sections Nuclear model calculations a b s t r a c t The 13.2 h half-life radioisotope 123 I is widely used in clinical nuclear medicine diagnosis. At present it is mostly produced in nca form by proton irradiation of highly enriched 124 Xe in dedicated gas target setups and relying on the decay chain 123 Cs-123 Xe-123 I. Depending on the irradiation conditions contamination with long-lived 121 Te, a daughter product of the co-produced rather short lived 121 I, occurs and can limit the useful shelf life of the 123 I solution. Excitation function of the 124 Xe(p,a) 121 I, 124 Xe(p,2n) 123 Cs and 124 Xe(p,2p) 123 Xe reactions are measured up to 35 MeV using the stacked gas cell technique and high-resolution gray spectrometry. The experimental data were compared with the earlier literature values, with new results of the ALICE-IPPE and EMPIRE-II codes and with the data taken from the TENDL-2009 database. Existing discrepancies in cross-section data are largely solved and new recommended values are proposed. From fits to the new excitation curves integral 123 I batch yields and 121 Te contaminations for realistic production conditions are derived. Optimization of irradiation and cooling times and energy degradation in the target can strongly influence the contamination level.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/60015210" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="746f7bf5a6d68c1fcd1f202941502afd" rel="nofollow" data-download="{"attachment_id":73647519,"asset_id":60015210,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/73647519/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="34686897" href="https://independent.academia.edu/AlexHermanne">Alex Hermanne</a><script data-card-contents-for-user="34686897" type="text/json">{"id":34686897,"first_name":"Alex","last_name":"Hermanne","domain_name":"independent","page_name":"AlexHermanne","display_name":"Alex Hermanne","profile_url":"https://independent.academia.edu/AlexHermanne?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_60015210 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="60015210"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 60015210, container: ".js-paper-rank-work_60015210", }); 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At present it is mostly produced in nca form by proton irradiation of highly enriched 124 Xe in dedicated gas target setups and relying on the decay chain 123 Cs-123 Xe-123 I. Depending on the irradiation conditions contamination with long-lived 121 Te, a daughter product of the co-produced rather short lived 121 I, occurs and can limit the useful shelf life of the 123 I solution. Excitation function of the 124 Xe(p,a) 121 I, 124 Xe(p,2n) 123 Cs and 124 Xe(p,2p) 123 Xe reactions are measured up to 35 MeV using the stacked gas cell technique and high-resolution gray spectrometry. The experimental data were compared with the earlier literature values, with new results of the ALICE-IPPE and EMPIRE-II codes and with the data taken from the TENDL-2009 database. Existing discrepancies in cross-section data are largely solved and new recommended values are proposed. From fits to the new excitation curves integral 123 I batch yields and 121 Te contaminations for realistic production conditions are derived. Optimization of irradiation and cooling times and energy degradation in the target can strongly influence the contamination level.","downloadable_attachments":[{"id":73647519,"asset_id":60015210,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":34686897,"first_name":"Alex","last_name":"Hermanne","domain_name":"independent","page_name":"AlexHermanne","display_name":"Alex Hermanne","profile_url":"https://independent.academia.edu/AlexHermanne?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":66912,"name":"SHELF LIFE","url":"https://www.academia.edu/Documents/in/SHELF_LIFE?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":309086,"name":"High 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itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/37087013/Survey_of_Orthopaedic_and_Sports_Medicine_Physicians_Regarding_Use_of_Medrol_Dosepak_for_Sports_Injuries">Survey of Orthopaedic and Sports Medicine Physicians Regarding Use of Medrol Dosepak for Sports Injuries</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: To study the use of a methylprednisolone taper (Medrol Dosepak; Pfizer, New York, NY) short-term oral corticosteroid treatment modality by sports medicine physicians; included is discussion on indications, perceived efficacy, and... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_37087013" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: To study the use of a methylprednisolone taper (Medrol Dosepak; Pfizer, New York, NY) short-term oral corticosteroid treatment modality by sports medicine physicians; included is discussion on indications, perceived efficacy, and complications. Methods: A survey specific to Medrol Dosepak (MDP) use was mailed to all members of the Arthroscopy Association of North America (AANA) and the American Orthopedic Society for Sports Medicine (AOSSM). Surveys were collected and data were collated and analyzed. Results: Total response rate was 41% (1,290/3,167), US response rate 43% (1,247/2,906), and international response rate 16% (43/261). Prescribing of MDP for sports injuries was significantly associated with average patient age Յ40 years ( square; P ϭ .001), but it was not associated with years in practice or patients seen per year. It was found that 47% of members (603/1,290) prescribe MDP. Postinjury disease was the most common indication. The most frequent complication was glucose intolerance (37%; 222/603). Of members who prescribe MDP, 8.5% (51/603) reported that they had seen 101 total cases of osteonecrosis, predominantly in the hip. Results revealed that 52% of members (672/1,290) do not prescribe MDP. The most frequent reasons for not prescribing included fear of osteonecrosis (30%; 201/672), fear of complications in general (27%; 183/672), lack of proven efficacy (27%; 180/672), and fear of malpractice (4.5%; 30/672). Of nonprescribing members (171/672), 25% had seen 500 cases of osteonecrosis, most often in the hip. Conclusions: The responding membership of AANA and AOSSM is evenly split regarding MDP use. Average patient age Յ40 years was associated with a greater likelihood that MDP would be prescribed for sports injuries. Postinjury disease is the most common indication; lack of proven efficacy and osteonecrosis are deterrents to prescription. Level of Evidence: Level V, expert opinion.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/37087013" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="02966153ee7d83282b62c199950ce37c" rel="nofollow" data-download="{"attachment_id":57038807,"asset_id":37087013,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/57038807/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="87627108" href="https://independent.academia.edu/MichaelHulstyn">Michael Hulstyn</a><script data-card-contents-for-user="87627108" type="text/json">{"id":87627108,"first_name":"Michael","last_name":"Hulstyn","domain_name":"independent","page_name":"MichaelHulstyn","display_name":"Michael Hulstyn","profile_url":"https://independent.academia.edu/MichaelHulstyn?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_37087013 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="37087013"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 37087013, container: ".js-paper-rank-work_37087013", }); 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Pfizer, New York, NY) short-term oral corticosteroid treatment modality by sports medicine physicians; included is discussion on indications, perceived efficacy, and complications. Methods: A survey specific to Medrol Dosepak (MDP) use was mailed to all members of the Arthroscopy Association of North America (AANA) and the American Orthopedic Society for Sports Medicine (AOSSM). Surveys were collected and data were collated and analyzed. Results: Total response rate was 41% (1,290/3,167), US response rate 43% (1,247/2,906), and international response rate 16% (43/261). Prescribing of MDP for sports injuries was significantly associated with average patient age Յ40 years ( square; P ϭ .001), but it was not associated with years in practice or patients seen per year. It was found that 47% of members (603/1,290) prescribe MDP. Postinjury disease was the most common indication. The most frequent complication was glucose intolerance (37%; 222/603). Of members who prescribe MDP, 8.5% (51/603) reported that they had seen 101 total cases of osteonecrosis, predominantly in the hip. Results revealed that 52% of members (672/1,290) do not prescribe MDP. The most frequent reasons for not prescribing included fear of osteonecrosis (30%; 201/672), fear of complications in general (27%; 183/672), lack of proven efficacy (27%; 180/672), and fear of malpractice (4.5%; 30/672). Of nonprescribing members (171/672), 25% had seen 500 cases of osteonecrosis, most often in the hip. Conclusions: The responding membership of AANA and AOSSM is evenly split regarding MDP use. Average patient age Յ40 years was associated with a greater likelihood that MDP would be prescribed for sports injuries. Postinjury disease is the most common indication; lack of proven efficacy and osteonecrosis are deterrents to prescription. Level of Evidence: Level V, expert opinion.","downloadable_attachments":[{"id":57038807,"asset_id":37087013,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":87627108,"first_name":"Michael","last_name":"Hulstyn","domain_name":"independent","page_name":"MichaelHulstyn","display_name":"Michael Hulstyn","profile_url":"https://independent.academia.edu/MichaelHulstyn?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":628,"name":"Orthopedic Surgery","url":"https://www.academia.edu/Documents/in/Orthopedic_Surgery?f_ri=10035","nofollow":true},{"id":640,"name":"Radiology","url":"https://www.academia.edu/Documents/in/Radiology?f_ri=10035","nofollow":true},{"id":646,"name":"Sports Medicine","url":"https://www.academia.edu/Documents/in/Sports_Medicine?f_ri=10035","nofollow":true},{"id":8942,"name":"Treatment","url":"https://www.academia.edu/Documents/in/Treatment?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine?f_ri=10035"},{"id":63890,"name":"Complication","url":"https://www.academia.edu/Documents/in/Complication?f_ri=10035"},{"id":66080,"name":"Age","url":"https://www.academia.edu/Documents/in/Age?f_ri=10035"},{"id":107083,"name":"Method","url":"https://www.academia.edu/Documents/in/Method?f_ri=10035"},{"id":113960,"name":"Orthopedics","url":"https://www.academia.edu/Documents/in/Orthopedics?f_ri=10035"},{"id":153168,"name":"Data Collection","url":"https://www.academia.edu/Documents/in/Data_Collection?f_ri=10035"},{"id":201844,"name":"Specialization","url":"https://www.academia.edu/Documents/in/Specialization?f_ri=10035"},{"id":204350,"name":"Anti-inflammatory agents","url":"https://www.academia.edu/Documents/in/Anti-inflammatory_agents?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":253469,"name":"North America","url":"https://www.academia.edu/Documents/in/North_America?f_ri=10035"},{"id":1364640,"name":"Short Term","url":"https://www.academia.edu/Documents/in/Short_Term?f_ri=10035"},{"id":2463781,"name":"Methylprednisolone","url":"https://www.academia.edu/Documents/in/Methylprednisolone?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_35871196" data-work_id="35871196" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/35871196/Temporomandibular_joint_arthrography_a_comparison_between_a_fluoroscopic_and_a_nonfluoroscopic_technique">Temporomandibular joint arthrography: a comparison between a fluoroscopic and a nonfluoroscopic technique</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">A nonfluoroscopic temporomandibular joint arthrographic technique is contrasted with a more widely employed fluoroscopically guided technique. The nonfluoroscopic technique uses a posterior approach to joint injection, as contrasted with... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_35871196" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">A nonfluoroscopic temporomandibular joint arthrographic technique is contrasted with a more widely employed fluoroscopically guided technique. The nonfluoroscopic technique uses a posterior approach to joint injection, as contrasted with the lateral injection approach of the fluoroscopically guided technique. The advantages of the nonfluoroscopic technique are less radiation dose to the patient, less expensive and less sophisticated imaging equipment, and less potential for neurovascular trauma. The fluoroscopic technique offers greater control of the procedure, less patient and operator time, and the capability for a dynamic videofluoroscopic study. Both techniques appear to be safe and efficacious. Differences in anatomy, imaging modalities, patient radiation exposure, and potential complications are also discussed as part of this comparison.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/35871196" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="a6b0a3c729b3f8867d7602d6018be1d5" rel="nofollow" data-download="{"attachment_id":55750607,"asset_id":35871196,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/55750607/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="50619749" href="https://independent.academia.edu/KennethAbramovitch">Kenneth Abramovitch</a><script data-card-contents-for-user="50619749" type="text/json">{"id":50619749,"first_name":"Kenneth","last_name":"Abramovitch","domain_name":"independent","page_name":"KennethAbramovitch","display_name":"Kenneth Abramovitch","profile_url":"https://independent.academia.edu/KennethAbramovitch?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_35871196 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="35871196"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 35871196, container: ".js-paper-rank-work_35871196", }); 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The nonfluoroscopic technique uses a posterior approach to joint injection, as contrasted with the lateral injection approach of the fluoroscopically guided technique. The advantages of the nonfluoroscopic technique are less radiation dose to the patient, less expensive and less sophisticated imaging equipment, and less potential for neurovascular trauma. The fluoroscopic technique offers greater control of the procedure, less patient and operator time, and the capability for a dynamic videofluoroscopic study. Both techniques appear to be safe and efficacious. Differences in anatomy, imaging modalities, patient radiation exposure, and potential complications are also discussed as part of this comparison.","downloadable_attachments":[{"id":55750607,"asset_id":35871196,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":50619749,"first_name":"Kenneth","last_name":"Abramovitch","domain_name":"independent","page_name":"KennethAbramovitch","display_name":"Kenneth Abramovitch","profile_url":"https://independent.academia.edu/KennethAbramovitch?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":9054,"name":"Temporomandibular Joint","url":"https://www.academia.edu/Documents/in/Temporomandibular_Joint?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":103404,"name":"Fluoroscopy","url":"https://www.academia.edu/Documents/in/Fluoroscopy?f_ri=10035","nofollow":true},{"id":336223,"name":"Digestive System","url":"https://www.academia.edu/Documents/in/Digestive_System?f_ri=10035","nofollow":true},{"id":389506,"name":"Radiation Dose","url":"https://www.academia.edu/Documents/in/Radiation_Dose?f_ri=10035"},{"id":1322049,"name":"Oral Surgery and Oral Medicine","url":"https://www.academia.edu/Documents/in/Oral_Surgery_and_Oral_Medicine?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_8090725" data-work_id="8090725" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/8090725/From_the_atomon_of_Democritus_to_the_therapeutic_nuclear_medicine_of_today">From the atomon of Democritus to the therapeutic nuclear medicine of today</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">By the beginning of the twentieth century, two of the fundamental laws in nature, those of gravity and electromagnetism, had been elucidated. The development of classical mechanics, from Galileo Galilei and Isaac Newton through to Joseph... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_8090725" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">By the beginning of the twentieth century, two of the fundamental laws in nature, those of gravity and electromagnetism, had been elucidated. The development of classical mechanics, from Galileo Galilei and Isaac Newton through to Joseph Louis Lagrange and William R. Hamilton, had proved the dominion of the law of gravity on earth and in the universe, while studies by Michael Faraday, James Clerk Maxwell and Heinrich R. Hertz on electromagnetic forces had made parallel potent contributions to scientific knowledge. The evolution of the kinetic theory of gases and thermodynamics had led scientists to consider matter in terms of molecular or atomic constituents. However, many properties of the basic building blocks of matter remained undiscovered or poorly understood.The quest for detailed knowledge of the fundamental constituents of matter dates back to the ancient world. In the 6th century B.C.E. 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The development of classical mechanics, from Galileo Galilei and Isaac Newton through to Joseph Louis Lagrange and William R. Hamilton, had proved the dominion of the law of gravity on earth and in the universe, while studies by Michael Faraday, James Clerk Maxwell and Heinrich R. Hertz on electromagnetic forces had made parallel potent contributions to scientific knowledge. The evolution of the kinetic theory of gases and thermodynamics had led scientists to consider matter in terms of molecular or atomic constituents. However, many properties of the basic building blocks of matter remained undiscovered or poorly understood.The quest for detailed knowledge of the fundamental constituents of matter dates back to the ancient world. In the 6th century B.C.E. (Before the Common Era), Kanada and Pakhuda Katyayana in ancient India had propounded ideas","downloadable_attachments":[{"id":48217391,"asset_id":8090725,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":15637945,"first_name":"GEORGIOS","last_name":"LIMOURIS","domain_name":"uoa","page_name":"GEORGIOSLIMOURIS","display_name":"GEORGIOS LIMOURIS","profile_url":"https://uoa.academia.edu/GEORGIOSLIMOURIS?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_13408281" data-work_id="13408281" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" rel="nofollow" href="https://www.academia.edu/13408281/Biological_evaluation_of_2_18F_fluoroflumazenil_18F_FFMZ_a_potential_GABA_receptor_ligand_for_PET">Biological evaluation of 2′-[18F]fluoroflumazenil ([18F]FFMZ), a potential GABA receptor ligand for PET</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">11 C]Flumazenil, a highly selective benzodiazepine antagonist is the most extensively used GABA A ligand for PET so far. To overcome half life disadvantages of 11 C a [ 18 F]-labeled flumazenil derivative, 2Ј-[ 18 F]fluoroflumazenil... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_13408281" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">11 C]Flumazenil, a highly selective benzodiazepine antagonist is the most extensively used GABA A ligand for PET so far. To overcome half life disadvantages of 11 C a [ 18 F]-labeled flumazenil derivative, 2Ј-[ 18 F]fluoroflumazenil (FFMZ) was developed and biologically evaluated with respect to the GABA A receptor. Organ with the highest uptake was the pituitary gland. Brain uptake was high and followed the order cortexϾthalamusϾcerebellumϾrest brain. Fluoroflumazenil displaced [ 3 H]flumazenil binding from membrane GABA A receptors with an IC 50 value (3.5 nM) comparable to that of Flumazenil (2.8 nM). The presented data confirm the potential of [ 18 F]FFMZ for PET imaging of the GABA-ergic system.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/13408281" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="f2a23e3ca4602ab6d9fd7e3cebf584d9" rel="nofollow" data-download="{"attachment_id":45375592,"asset_id":13408281,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/45375592/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32630027" rel="nofollow" href="https://meduniwien.academia.edu/WernerSieghart">Werner Sieghart</a><script data-card-contents-for-user="32630027" type="text/json">{"id":32630027,"first_name":"Werner","last_name":"Sieghart","domain_name":"meduniwien","page_name":"WernerSieghart","display_name":"Werner Sieghart","profile_url":"https://meduniwien.academia.edu/WernerSieghart?f_ri=10035","photo":"https://0.academia-photos.com/32630027/18245501/18220329/s65_werner.sieghart.jpg"}</script></span></span></li><li class="js-paper-rank-work_13408281 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="13408281"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 13408281, container: ".js-paper-rank-work_13408281", }); 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To overcome half life disadvantages of 11 C a [ 18 F]-labeled flumazenil derivative, 2Ј-[ 18 F]fluoroflumazenil (FFMZ) was developed and biologically evaluated with respect to the GABA A receptor. Organ with the highest uptake was the pituitary gland. Brain uptake was high and followed the order cortexϾthalamusϾcerebellumϾrest brain. Fluoroflumazenil displaced [ 3 H]flumazenil binding from membrane GABA A receptors with an IC 50 value (3.5 nM) comparable to that of Flumazenil (2.8 nM). The presented data confirm the potential of [ 18 F]FFMZ for PET imaging of the GABA-ergic system.","downloadable_attachments":[{"id":45375592,"asset_id":13408281,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32630027,"first_name":"Werner","last_name":"Sieghart","domain_name":"meduniwien","page_name":"WernerSieghart","display_name":"Werner Sieghart","profile_url":"https://meduniwien.academia.edu/WernerSieghart?f_ri=10035","photo":"https://0.academia-photos.com/32630027/18245501/18220329/s65_werner.sieghart.jpg"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035","nofollow":true},{"id":61474,"name":"Brain","url":"https://www.academia.edu/Documents/in/Brain?f_ri=10035","nofollow":true},{"id":89803,"name":"GABA receptors","url":"https://www.academia.edu/Documents/in/GABA_receptors?f_ri=10035","nofollow":true},{"id":96379,"name":"PET imaging","url":"https://www.academia.edu/Documents/in/PET_imaging?f_ri=10035"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035"},{"id":293670,"name":"Pituitary Gland","url":"https://www.academia.edu/Documents/in/Pituitary_Gland?f_ri=10035"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats?f_ri=10035"},{"id":784086,"name":"Radiopharmaceuticals","url":"https://www.academia.edu/Documents/in/Radiopharmaceuticals?f_ri=10035"},{"id":1222191,"name":"Ligands","url":"https://www.academia.edu/Documents/in/Ligands?f_ri=10035"},{"id":1715791,"name":"GABA receptor","url":"https://www.academia.edu/Documents/in/GABA_receptor?f_ri=10035"},{"id":2223059,"name":"Flumazenil","url":"https://www.academia.edu/Documents/in/Flumazenil?f_ri=10035"}]}, }) } 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obtained at the level of the carpal tunnel (CSAc) with those obtained more proximally (CSAp), at... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_24238675" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">To improve accuracy in the diagnosis of carpal tunnel syndrome (CTS) by comparing cross-sectional area (CSA) measurements of the median nerve obtained at the level of the carpal tunnel (CSAc) with those obtained more proximally (CSAp), at the level of the pronator quadratus muscle.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/24238675" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" 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muscle.","downloadable_attachments":[{"id":44572891,"asset_id":24238675,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":46713181,"first_name":"Tobias De","last_name":"Zordo","domain_name":"independent","page_name":"TobiasDeZordo","display_name":"Tobias De Zordo","profile_url":"https://independent.academia.edu/TobiasDeZordo?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":640,"name":"Radiology","url":"https://www.academia.edu/Documents/in/Radiology?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":22506,"name":"Adolescent","url":"https://www.academia.edu/Documents/in/Adolescent?f_ri=10035","nofollow":true},{"id":23890,"name":"Comparative Study","url":"https://www.academia.edu/Documents/in/Comparative_Study?f_ri=10035","nofollow":true},{"id":133057,"name":"Young Adult","url":"https://www.academia.edu/Documents/in/Young_Adult?f_ri=10035"},{"id":220450,"name":"Carpal Tunnel Syndrome","url":"https://www.academia.edu/Documents/in/Carpal_Tunnel_Syndrome?f_ri=10035"},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":325234,"name":"Compression","url":"https://www.academia.edu/Documents/in/Compression?f_ri=10035"},{"id":901876,"name":"Sensitivity and Specificity","url":"https://www.academia.edu/Documents/in/Sensitivity_and_Specificity?f_ri=10035"},{"id":1000427,"name":"Reference Values","url":"https://www.academia.edu/Documents/in/Reference_Values?f_ri=10035"},{"id":1292780,"name":"Median Nerve","url":"https://www.academia.edu/Documents/in/Median_Nerve?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_23991747" data-work_id="23991747" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/23991747/Single_photon_avalanche_photodiodes_with_integrated_quenching_resistor">Single-photon avalanche photodiodes with integrated quenching resistor</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">In this paper we present the results of the first electrical and optical characterization performed on STMicroelectronics new photosensor technology based on silicon single-photon avalanche photodiodes (SPAD). On the prospective of the... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_23991747" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">In this paper we present the results of the first electrical and optical characterization performed on STMicroelectronics new photosensor technology based on silicon single-photon avalanche photodiodes (SPAD). On the prospective of the design and the manufacturing of large-area silicon photomultipliers to be used as photodetectors for nuclear medicine imaging applications, we have modified our previous SPAD technology by means of the integration of a high-value quenching resistor to the photodiode. Moreover, an appropriate antireflective coating layer and the reduction of the quasi-neutral region thickness above the thin junction depletion layer have been introduced in the process flow of the device to enhance its spectral response in blue and near ultraviolet wavelength ranges. High gain, low leakage currents, low dark noise, very good quantum detection efficiency in blue-near UV ranges and a good linearity of the photodiode response to the incident luminous flux are the main characterization results. r</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/23991747" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="599dd9e1cf39ad264c55ad13f9220130" rel="nofollow" data-download="{"attachment_id":44380149,"asset_id":23991747,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/44380149/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="32235378" href="https://independent.academia.edu/PaoloFinocchiaro">Paolo Finocchiaro</a><script data-card-contents-for-user="32235378" type="text/json">{"id":32235378,"first_name":"Paolo","last_name":"Finocchiaro","domain_name":"independent","page_name":"PaoloFinocchiaro","display_name":"Paolo Finocchiaro","profile_url":"https://independent.academia.edu/PaoloFinocchiaro?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_23991747 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="23991747"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 23991747, container: ".js-paper-rank-work_23991747", }); 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$(".js-view-count[data-work-id=23991747]").text(description); $(".js-view-count-work_23991747").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_23991747").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="23991747"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">3</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="87546" rel="nofollow" href="https://www.academia.edu/Documents/in/Ultraviolet">Ultraviolet</a>, <script data-card-contents-for-ri="87546" type="text/json">{"id":87546,"name":"Ultraviolet","url":"https://www.academia.edu/Documents/in/Ultraviolet?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="121477" rel="nofollow" href="https://www.academia.edu/Documents/in/Leakage_Current">Leakage Current</a><script data-card-contents-for-ri="121477" type="text/json">{"id":121477,"name":"Leakage Current","url":"https://www.academia.edu/Documents/in/Leakage_Current?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=23991747]'), work: {"id":23991747,"title":"Single-photon avalanche photodiodes with integrated quenching resistor","created_at":"2016-04-04T01:33:51.460-07:00","url":"https://www.academia.edu/23991747/Single_photon_avalanche_photodiodes_with_integrated_quenching_resistor?f_ri=10035","dom_id":"work_23991747","summary":"In this paper we present the results of the first electrical and optical characterization performed on STMicroelectronics new photosensor technology based on silicon single-photon avalanche photodiodes (SPAD). On the prospective of the design and the manufacturing of large-area silicon photomultipliers to be used as photodetectors for nuclear medicine imaging applications, we have modified our previous SPAD technology by means of the integration of a high-value quenching resistor to the photodiode. Moreover, an appropriate antireflective coating layer and the reduction of the quasi-neutral region thickness above the thin junction depletion layer have been introduced in the process flow of the device to enhance its spectral response in blue and near ultraviolet wavelength ranges. High gain, low leakage currents, low dark noise, very good quantum detection efficiency in blue-near UV ranges and a good linearity of the photodiode response to the incident luminous flux are the main characterization results. r","downloadable_attachments":[{"id":44380149,"asset_id":23991747,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":32235378,"first_name":"Paolo","last_name":"Finocchiaro","domain_name":"independent","page_name":"PaoloFinocchiaro","display_name":"Paolo Finocchiaro","profile_url":"https://independent.academia.edu/PaoloFinocchiaro?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":87546,"name":"Ultraviolet","url":"https://www.academia.edu/Documents/in/Ultraviolet?f_ri=10035","nofollow":true},{"id":121477,"name":"Leakage Current","url":"https://www.academia.edu/Documents/in/Leakage_Current?f_ri=10035","nofollow":true}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_22865746" data-work_id="22865746" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/22865746/Long_term_results_of_post_operative_radiation_therapy_following_mastectomy_with_or_without_chemotherapy_in_stage_I_III_breast_cancer">Long-term results of post-operative radiation therapy following mastectomy with or without chemotherapy in stage I–III breast cancer</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Purpose: To determine the risk of local-regional failure following post-mastectomy radiotherapy and the incidence of complications associated with such treatment. Methods and Materials: We retrospectively analyzed the results in 309... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_22865746" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Purpose: To determine the risk of local-regional failure following post-mastectomy radiotherapy and the incidence of complications associated with such treatment. Methods and Materials: We retrospectively analyzed the results in 309 patients with Stage I-III invasive breast cancer treated with post-mastectomy radiation therapy between 1975 and 1985. The median radiotherapy dose was 45 Gy in 1.8 to 2.25 Gy fractions. One hundred forty-seven (48%) of the patients received adjuvant systemic chemotherapy with 115 (78%) of these receiving a CMF-based or doxorubicin-containing regimen. The median follow-up time of surviving patients was 130 months (range, 28 to 191 months) after mastectomy. Results: Seventeen patients (6%) developed a local-regional failure at an interval of 4 to 87 months after radiotherapy. Moderate or severe complications related to radiotherapy and requiring treatment were uncommon. Symptomatic radiation pneumonitis occurred in four patients (1.3%), arm edema in 18 (5.8%), and brachial plexopathy in 2 (0.6%).</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/22865746" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="4809b6bcd6905ef122056e5a723f9ed7" rel="nofollow" data-download="{"attachment_id":43405888,"asset_id":22865746,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/43405888/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="44523490" href="https://umassmed.academia.edu/BruceBornstein">Bruce Bornstein</a><script data-card-contents-for-user="44523490" type="text/json">{"id":44523490,"first_name":"Bruce","last_name":"Bornstein","domain_name":"umassmed","page_name":"BruceBornstein","display_name":"Bruce Bornstein","profile_url":"https://umassmed.academia.edu/BruceBornstein?f_ri=10035","photo":"/images/s65_no_pic.png"}</script></span></span></li><li class="js-paper-rank-work_22865746 InlineList-item InlineList-item--bordered hidden"><span class="js-paper-rank-view hidden u-tcGrayDark" data-paper-rank-work-id="22865746"><i class="u-m1x fa fa-bar-chart"></i><strong class="js-paper-rank"></strong></span><script>$(function() { new Works.PaperRankView({ workId: 22865746, container: ".js-paper-rank-work_22865746", }); });</script></li><li class="js-percentile-work_22865746 InlineList-item InlineList-item--bordered hidden u-tcGrayDark"><span class="percentile-widget hidden"><span class="u-mr2x percentile-widget" style="display: none">•</span><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 22865746; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-percentile-work_22865746"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></li><li class="js-view-count-work_22865746 InlineList-item InlineList-item--bordered hidden"><div><span><span class="js-view-count view-count u-mr2x" data-work-id="22865746"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 22865746; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=22865746]").text(description); $(".js-view-count-work_22865746").attr('title', description).tooltip(); }); });</script></span><script>$(function() { $(".js-view-count-work_22865746").removeClass('hidden') })</script></div></li><li class="InlineList-item u-positionRelative" style="max-width: 250px"><div class="u-positionAbsolute" data-has-card-for-ri-list="22865746"><i class="fa fa-tag InlineList-item-icon u-positionRelative"></i>  <a class="InlineList-item-text u-positionRelative">7</a>  </div><span class="InlineList-item-text u-textTruncate u-pl9x"><a class="InlineList-item-text" data-has-card-for-ri="6802" rel="nofollow" href="https://www.academia.edu/Documents/in/Breast_Cancer">Breast Cancer</a>, <script data-card-contents-for-ri="6802" type="text/json">{"id":6802,"name":"Breast Cancer","url":"https://www.academia.edu/Documents/in/Breast_Cancer?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10030" rel="nofollow" href="https://www.academia.edu/Documents/in/Radiation_Therapy">Radiation Therapy</a>, <script data-card-contents-for-ri="10030" type="text/json">{"id":10030,"name":"Radiation Therapy","url":"https://www.academia.edu/Documents/in/Radiation_Therapy?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="10035" rel="nofollow" href="https://www.academia.edu/Documents/in/Nuclear_medicine">Nuclear medicine</a>, <script data-card-contents-for-ri="10035" type="text/json">{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true}</script><a class="InlineList-item-text" data-has-card-for-ri="244814" rel="nofollow" href="https://www.academia.edu/Documents/in/Clinical_Sciences">Clinical Sciences</a><script data-card-contents-for-ri="244814" type="text/json">{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true}</script></span></li><script>(function(){ if (true) { new Aedu.ResearchInterestListCard({ el: $('*[data-has-card-for-ri-list=22865746]'), work: {"id":22865746,"title":"Long-term results of post-operative radiation therapy following mastectomy with or without chemotherapy in stage I–III breast cancer","created_at":"2016-03-05T17:32:15.834-08:00","url":"https://www.academia.edu/22865746/Long_term_results_of_post_operative_radiation_therapy_following_mastectomy_with_or_without_chemotherapy_in_stage_I_III_breast_cancer?f_ri=10035","dom_id":"work_22865746","summary":"Purpose: To determine the risk of local-regional failure following post-mastectomy radiotherapy and the incidence of complications associated with such treatment. Methods and Materials: We retrospectively analyzed the results in 309 patients with Stage I-III invasive breast cancer treated with post-mastectomy radiation therapy between 1975 and 1985. The median radiotherapy dose was 45 Gy in 1.8 to 2.25 Gy fractions. One hundred forty-seven (48%) of the patients received adjuvant systemic chemotherapy with 115 (78%) of these receiving a CMF-based or doxorubicin-containing regimen. The median follow-up time of surviving patients was 130 months (range, 28 to 191 months) after mastectomy. Results: Seventeen patients (6%) developed a local-regional failure at an interval of 4 to 87 months after radiotherapy. Moderate or severe complications related to radiotherapy and requiring treatment were uncommon. Symptomatic radiation pneumonitis occurred in four patients (1.3%), arm edema in 18 (5.8%), and brachial plexopathy in 2 (0.6%).","downloadable_attachments":[{"id":43405888,"asset_id":22865746,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":44523490,"first_name":"Bruce","last_name":"Bornstein","domain_name":"umassmed","page_name":"BruceBornstein","display_name":"Bruce Bornstein","profile_url":"https://umassmed.academia.edu/BruceBornstein?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":6802,"name":"Breast Cancer","url":"https://www.academia.edu/Documents/in/Breast_Cancer?f_ri=10035","nofollow":true},{"id":10030,"name":"Radiation Therapy","url":"https://www.academia.edu/Documents/in/Radiation_Therapy?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences?f_ri=10035","nofollow":true},{"id":289271,"name":"Aged","url":"https://www.academia.edu/Documents/in/Aged?f_ri=10035"},{"id":424295,"name":"Survival Rate","url":"https://www.academia.edu/Documents/in/Survival_Rate?f_ri=10035"},{"id":469105,"name":"Retrospective Studies","url":"https://www.academia.edu/Documents/in/Retrospective_Studies?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_20381894" data-work_id="20381894" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/20381894/Acceleration_and_filtering_in_the_generalized_Landweber_iteration_using_a_variable_shaping_matrix">Acceleration and filtering in the generalized Landweber iteration using a variable shaping matrix</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Abstruct-We use the generalized Landweber iteration with a variable shaping matrix to solve the large linear system of equations arising in the image reconstruction problem of emission tomography. Our method is based on the property that... <a class="more_link u-tcGrayDark u-linkUnstyled" data-container=".work_20381894" data-show=".complete" data-hide=".summarized" data-more-link-behavior="true" href="#">more</a></div><div class="complete hidden">Abstruct-We use the generalized Landweber iteration with a variable shaping matrix to solve the large linear system of equations arising in the image reconstruction problem of emission tomography. Our method is based on the property that once a spatial frequency image component is almost recovered within E in the generalized Landweber iteration, this component will still stay within E during subsequent iterations with a different shaping matrix, as long as this shaping matrix satisfies the convergence criterion for the component. Two different shaping matrices are used: the first recovers low-frequency image components; and the second may be used either to accelerate the reconstruction of high-frequency image components, or to attenuate these components to filter the image. The variable shaping matrix gives results similar to truncated inverse filtering, but requires much less computation and memory, since it does not rely on the singular value decomposition.</div></div></div><ul class="InlineList u-ph0x u-fs13"><li class="InlineList-item logged_in_only"><div class="share_on_academia_work_button"><a class="academia_share Button Button--inverseBlue Button--sm js-bookmark-button" data-academia-share="Work/20381894" data-share-source="work_strip" data-spinner="small_white_hide_contents"><i class="fa fa-plus"></i><span class="work-strip-link-text u-ml1x" data-content="button_text">Bookmark</span></a></div></li><li class="InlineList-item"><div class="download"><a id="e1802c367cb80ce9894dab2b6665aeed" rel="nofollow" data-download="{"attachment_id":41963505,"asset_id":20381894,"asset_type":"Work","always_allow_download":false,"track":null,"button_location":"work_strip","source":null,"hide_modal":null}" class="Button Button--sm Button--inverseGreen js-download-button prompt_button doc_download" href="https://www.academia.edu/attachments/41963505/download_file?st=MTc0MDU3MDk0OSw4LjIyMi4yMDguMTQ2&s=work_strip"><i class="fa fa-arrow-circle-o-down fa-lg"></i><span class="u-textUppercase u-ml1x" data-content="button_text">Download</span></a></div></li><li class="InlineList-item"><ul class="InlineList InlineList--bordered u-ph0x"><li class="InlineList-item InlineList-item--bordered"><span class="InlineList-item-text">by <span itemscope="itemscope" itemprop="author" itemtype="https://schema.org/Person"><a class="u-tcGrayDark u-fw700" data-has-card-for-user="41739210" href="https://umich.academia.edu/AYagle">A.E. Yagle</a><script data-card-contents-for-user="41739210" type="text/json">{"id":41739210,"first_name":"A.E.","last_name":"Yagle","domain_name":"umich","page_name":"AYagle","display_name":"A.E. 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Our method is based on the property that once a spatial frequency image component is almost recovered within E in the generalized Landweber iteration, this component will still stay within E during subsequent iterations with a different shaping matrix, as long as this shaping matrix satisfies the convergence criterion for the component. Two different shaping matrices are used: the first recovers low-frequency image components; and the second may be used either to accelerate the reconstruction of high-frequency image components, or to attenuate these components to filter the image. The variable shaping matrix gives results similar to truncated inverse filtering, but requires much less computation and memory, since it does not rely on the singular value decomposition.","downloadable_attachments":[{"id":41963505,"asset_id":20381894,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":41739210,"first_name":"A.E.","last_name":"Yagle","domain_name":"umich","page_name":"AYagle","display_name":"A.E. Yagle","profile_url":"https://umich.academia.edu/AYagle?f_ri=10035","photo":"/images/s65_no_pic.png"}],"research_interests":[{"id":48,"name":"Engineering","url":"https://www.academia.edu/Documents/in/Engineering?f_ri=10035","nofollow":true},{"id":1185,"name":"Image Processing","url":"https://www.academia.edu/Documents/in/Image_Processing?f_ri=10035","nofollow":true},{"id":5057,"name":"Iterative Methods","url":"https://www.academia.edu/Documents/in/Iterative_Methods?f_ri=10035","nofollow":true},{"id":10035,"name":"Nuclear medicine","url":"https://www.academia.edu/Documents/in/Nuclear_medicine?f_ri=10035","nofollow":true},{"id":15124,"name":"Convergence","url":"https://www.academia.edu/Documents/in/Convergence?f_ri=10035"},{"id":23518,"name":"Positron Emission Tomography","url":"https://www.academia.edu/Documents/in/Positron_Emission_Tomography?f_ri=10035"},{"id":30372,"name":"Low Frequency","url":"https://www.academia.edu/Documents/in/Low_Frequency?f_ri=10035"},{"id":36022,"name":"Tomography","url":"https://www.academia.edu/Documents/in/Tomography?f_ri=10035"},{"id":48458,"name":"High Frequency","url":"https://www.academia.edu/Documents/in/High_Frequency?f_ri=10035"},{"id":71001,"name":"Image Reconstruction","url":"https://www.academia.edu/Documents/in/Image_Reconstruction?f_ri=10035"},{"id":85880,"name":"Singular value decomposition","url":"https://www.academia.edu/Documents/in/Singular_value_decomposition?f_ri=10035"},{"id":144046,"name":"Frequency","url":"https://www.academia.edu/Documents/in/Frequency?f_ri=10035"},{"id":155840,"name":"Spatial Frequency","url":"https://www.academia.edu/Documents/in/Spatial_Frequency?f_ri=10035"},{"id":201957,"name":"Acceleration","url":"https://www.academia.edu/Documents/in/Acceleration?f_ri=10035"},{"id":350706,"name":"Linear Systems","url":"https://www.academia.edu/Documents/in/Linear_Systems?f_ri=10035"},{"id":370219,"name":"Matrix Decomposition","url":"https://www.academia.edu/Documents/in/Matrix_Decomposition?f_ri=10035"},{"id":604200,"name":"Spatial resolution","url":"https://www.academia.edu/Documents/in/Spatial_resolution?f_ri=10035"},{"id":679783,"name":"Boolean Satisfiability","url":"https://www.academia.edu/Documents/in/Boolean_Satisfiability?f_ri=10035"},{"id":728952,"name":"Filtering","url":"https://www.academia.edu/Documents/in/Filtering?f_ri=10035"}]}, }) } })();</script></ul></li></ul></div></div><div class="u-borderBottom1 u-borderColorGrayLighter"><div class="clearfix u-pv7x u-mb0x js-work-card work_77324621" data-work_id="77324621" itemscope="itemscope" itemtype="https://schema.org/ScholarlyArticle"><div class="header"><div class="title u-fontSerif u-fs22 u-lineHeight1_3"><a class="u-tcGrayDarkest js-work-link" href="https://www.academia.edu/77324621/1st_International_Symposium_on_Radionuclide_Therapy_and_Radiopharmaceutical_Dosimetry">1st International Symposium on Radionuclide Therapy and Radiopharmaceutical Dosimetry</a></div></div><div class="u-pb4x u-mt3x"><div class="summary u-fs14 u-fw300 u-lineHeight1_5 u-tcGrayDarkest"><div class="summarized">Das Werk ist urheberrechtlich geschützt. 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Die dadurch begründeten Rechte, insbesondere die der Übersetzung, des Nachdrucks, des Vortrages, der Entnahme von Abbildungen, der Funksendung, der Wiedergabe auf photomechanischem oder ähnlichem Wege und der Speicherung in Datenverarbeitungsanlagen, bleiben bei auch nur auszugsweiser Verwertung vorbehalten. Eine Vervielfältigung dieses Werkes oder von Teilen dieses Werkes ist auch im Einzelfall nur in den Grenzen der gesetzlichen Bestimmungen des Urheberrechtsgesetzes der Bundesrepublik Deutschland vom 9. September 1965 in der Fassung vom 24. Juni 1985 zulässig. Sie ist grundsätzlich vergütungspfl ichtig. Zuwiderhandlungen unterliegen den Strafbestimmungen des Urheberrechtsgesetzes.","downloadable_attachments":[{"id":84731613,"asset_id":77324621,"asset_type":"Work","always_allow_download":false}],"ordered_authors":[{"id":12215381,"first_name":"Cristiano","last_name":"Fragassa","domain_name":"unibo","page_name":"CristianoFragassa","display_name":"Cristiano Fragassa","profile_url":"https://unibo.academia.edu/CristianoFragassa?f_ri=10035","photo":"https://0.academia-photos.com/12215381/3506921/4118629/s65_cristiano.fragassa.jpg"}],"research_interests":[{"id":1011,"name":"Library Science","url":"https://www.academia.edu/Documents/in/Library_Science?f_ri=10035","nofollow":true},{"id":2513,"name":"Molecular 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