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Glossary | IPRCC

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</fieldset> </div> <div class="col-12 col-md-auto title-search"> <button data-drupal-selector="edit-submit-glossary-terms" type="submit" id="views-exposed-form-glossary-terms-glossary-terms-edit-title-search" value="Search" class="button js-form-submit form-submit btn btn-ninds">Search</button> </div> <div class="col-auto toggle-subscribe-button"> <button class="btn btn-ninds collapsed" type="button" data-toggle="collapse" data-target=".view-footer" aria-expanded="false" aria-controls="view-footer"> <i class="fa fa-envelope" aria-hidden="true"></i> <div class="buttonText">Subscribe</div> </button> </div> </div> </form> </div> <div class="view-header"> <div class="a-z-header view view-glossary-terms view-id-glossary_terms view-display-id-block_1 js-view-dom-id-f6d4a9e43f57e68cf1dcd1a88fb7aa21c666e742c702bb591b7d3918f5ec29ef"> <div class="view-content"> <div class="col-12"> <span class="views-summary views-summary-unformatted"> <a href="/glossary/2">2</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/a">A</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/b">B</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/c">C</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/d">D</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/e">E</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/f">F</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/g">G</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/h">H</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/i">I</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/k">K</a> </span> <span class="views-summary views-summary-unformatted"> <a href="/glossary/m">M</a> </span> <span 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class="views-row col-12"> <h2 class="views-field views-field-name"><span class="field-content">NIH</span></h2><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">National Institutes of Health - A Federal agency whose mission is to improve the health of the people of the United States. NIH is a part of the Public Health Service, which is part of the U.S. Department of Health and Human Services. </div></div> </div> </div> </div> </div> <div class="view-content"> <div class="views-group-title col-12"> <h2>2</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="21st-century-cures">21st Century Cures</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">The 21st Century Cures Act (Cures Act), signed into law on December 13, 2016,provides multiyear funding to four highly innovative scientific initiatives, including the NIH BRAIN Initiative. </div></div> </div> <div class="views-group-title col-12"> <h2>A</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="awarding-ic">Awarding IC</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">The NIH Institute/Center (IC) responsible for the award, administration, and monitoring of grant supported activities.</div></div> </div> <div class="views-group-title col-12"> <h2>C</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="common-fund">Common Fund</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">The NIH Common Fund supports cross-cutting, trans-NIH programs, including those referred to as NIH Roadmap programs. See <a href="http://commonfund.nih.gov/">The NIH Common Fund</a>.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="competing-applications">Competing Applications</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><p>Competing applications are applications for a new, renewal, or resubmission&nbsp;<a href="http://grants.nih.gov/grants/glossary.htm%22%20%5Cl%20%22ResearchProjectGrant(RPG)">research project grants(RPG)</a>, including R01s, R21s, and related mechanisms, that require competitive peer review</p></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="contact-pd/pi">Contact PD/PI</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">When multiple PD/PIs are designated, NIH requires that the applicant organization identify one of the PD/PIs as the Contact PD/PI to serve as a primary point of contact. Serving as Contact PD/PI confers no special authorities or responsibilities within the project team. The Contact PD/PI must meet all eligibility requirements for PD/PI status. However, as with the single PD/PI model, if the Contact PD/PI is not an employee, the applicant organization must have a formal written agreement with the Contact PD/PI that specifies an official relationship between the parties. (See <a href="http://grants.nih.gov/grants/policy/nihgps/HTML5/section_9/9_multiple_program_director_principal_investigator_applications_and_awards.htm"><strong><em>NIH Grants Policy Statement</em></strong><strong>:</strong> <strong>9 </strong> Multiple Program director/Principal Investigator Applications and Awards</a>)</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="council-round">Council Round</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">At the NIH, there are at least three, and sometimes four, council rounds each fiscal year: October, January, May, and sometimes August. Application receipt dates, initial review dates, and council review dates all fall within one of these council rounds. </div></div> </div> <div class="views-group-title col-12"> <h2>D</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="data-and-safety-monitoring-board-(dsmb)">Data and Safety Monitoring Board (DSMB)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">A formal, independent board of experts including investigators and biostatisticians that advise study investigators regarding the safety progression of a study. In general, NIH requires the establishment of DSMBs for multi-site clinical trials involving interventions that entail potential risk to the participants and for all Phase III clinical trials. As necessary, a DSMB may be appropriate for Phase I and Phase II or other clinical trials if the studies are blinded (masked), employ high-risk interventions, or involve vulnerable populations.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="data-and-safety-monitoring-plan">Data and Safety Monitoring Plan</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">Prior to award, this plan must be approved by the applicant‚Äôs IRB and the NIH awarding IC prior to the accrual of human subjects. The reporting of Adverse Events must be reported to the IRB, the DSMB (if applicable) or other monitoring entity, the NIH funding Institute or Center, and other required entities. This policy requirement is in addition to any monitoring requirements imposed by <a href="https://www.hhs.gov/ohrp/regulations-and-policy/regulations/45-cfr-46/index.html">45 CFR part 46</a>.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="direct-costs">Direct Costs</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">Costs that can be identified specifically with a particular sponsored project, an instructional activity, or any other institutional activity, or that can be directly assigned to such activities relatively easily with a high degree of accuracy. (<em>See <a href="http://grants.nih.gov/grants/policy/nihgps/HTML5/section_7/7.3_direct_costs_and_facilities_and_administrative_costs.htm">NIH Grants Policy Statement 7.3 Direct Costs and Facilities and Administrative Costs</a></em>)</div></div> </div> <div class="views-group-title col-12"> <h2>E</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="early-established-investigator-(eei)">Early Established Investigator (EEI)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">A Program Director / Principal Investigator (PD/PI) who is within 10 years of receiving their first substantial, independent competing NIH <a href="#r0-equivalent-grant">R01 equivalent</a> research award as an <a href="#early-stage-investigator-(esi)">Early Stage Investigator (ESI)</a>.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="early-stage-investigator-(esi)">Early Stage Investigator (ESI)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><div> A Program Director / Principal Investigator (PD/PI) who has completed their terminal research degree or end of post-graduate clinical training, whichever date is later, within the past 10 years and who has not previously competed successfully as PD/PI for a substantial NIH independent research award. A list of NIH grants that a PD/PI can hold and still be considered an ESI can be found at <a href="https://grants.nih.gov/policy/early-investigators/list-smaller-grants.htm">https://grants.nih.gov/policy/early-investigators/list-smaller-grants.htm</a>. </div> <div> </div> <div> </div> <div> </div></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="early-stage-investigator-esi">Early Stage Investigator ESI</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><p>An Early Stage Investigator is a Program Director / Principal Investigator (PD/PI) who has completed their terminal research degree or end of post-graduate clinical training, whichever date is later, within the past 10 years and who has not previously competed successfully as PD/PI for a substantial NIH independent research award.&nbsp; See our <a href="http://grants.nih.gov/policy/early-investigators/list-smaller-grants.htm">list of NIH grants that a PD/PI can hold and still be considered an ESI.</a> For more information, please click <a href="https://grants.nih.gov/policy/early-investigators/index.htm">here</a>.<i> </i></p></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="extramural-awards">Extramural Awards</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">Funds provided by the NIH to researchers and organizations outside the NIH.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="extramural-research">Extramural Research</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">Research supported by NIH through a grant, contract, or cooperative agreement.</div></div> </div> <div class="views-group-title col-12"> <h2>F</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="fic">FIC</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><a href="http://www.fic.nih.gov/">NIH Fogarty International Center</a></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="freedom-of-information-act-(foia)">Freedom of Information Act (FOIA)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">Requires dissemination, upon request, of Government documents while ensuring protection of proprietary and other privacy act information. Go to <a href="http://www.nih.gov/icd/od/foia/index.htm">FOIA</a>.</div></div> </div> <div class="views-group-title col-12"> <h2>G</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="grant-number">Grant Number</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><ul> <li> <a href="#application-type-code">type of application</a> (1) </li> <li> <a href="#activity-code">activity code</a> (R01) </li> <li> <a href="#institute-or-center-(ic)">organization</a> to which it is assigned (AI) </li> <li> serial number assigned by the <a href="http://public.csr.nih.gov/Pages/default.aspx">Center for Scientific Review</a> (183723), </li> <li> suffix showing the support year for the grant (-01) </li> <li> other information identifying a<a href="#revision"> revision</a> (S1), <a href="#resubmission">resubmission</a> (A1), or a fellowship's institutional allowance. For contracts, the suffix is replaced by a modification number. </li> </ul> <p> <strong>Sample Grant Number </strong>1 R01 AI 183723 -01 A1 S1 </p></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="grant-or-grant-agreement">Grant or Grant Agreement</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><p> A legal instrument of financial assistance between a Federal awarding agency or pass-through entity and a non-Federal entity that, consistent with 31 U.S.C. 6302, 6304:<br> (1) Is used to enter into a relationship the principal purpose of which is to transfer anything of value from the Federal awarding agency or pass-through entity to the non-Federal entity to carry out a public purpose authorized by a law of the United States (see 31 U.S.C. 6101(3)); and not to acquire property or services for the Federal awarding agency or pass-through entity's direct benefit or use;<br> (2) Is distinguished from a cooperative agreement in that it does not provide for substantial involvement between the Federal awarding agency or pass-through entity and the non-Federal entity in carrying out the activity contemplated by the Federal award.<br> (3) Does not include an agreement that provides only: </p> <p> <br> (i) Direct United States Government cash assistance to an individual;<br> (ii) A subsidy;<br> (iii) A loan;<br> (iv) A loan guarantee; or<br> (v) Insurance. </p> See <a href="http://grants.nih.gov/grants/policy/nihgps/HTML5/section_1/1.2_definition_of_terms.htm#Cooperative_agreement"><strong><em>NIH Grants Policy Statement</em></strong>: 1.2 Definition of Terms Cooperative Agreement.</a></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="grants-management-officer-(gmo)">Grants Management Officer (GMO)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">An NIH official responsible for the business management aspects of grants and cooperative agreements, including review, negotiation, award, and administration, and for the interpretation of grants administration policies and provisions. GMOs are delegated the authority from the CGMO to obligate NIH to the expenditure of funds and permit changes to approved projects on behalf of NIH. Each NIH IC that awards grants has one or more GMOs with responsibility for particular programs or awards. See also <a href="http://grants.nih.gov/grants/policy/nihgps/HTML5/section_1/1.2_definition_of_terms.htm#Chief_Grants_Management_Officer">Chief Grants Management Officer</a> definition.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="grants-management-specialist-(gms)">Grants Management Specialist (GMS)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">A NIH staff member who oversees the business and other non-programmatic aspects of one or more grants and/or cooperative agreements. These activities include, but are not limited to, evaluating grant applications for administrative content and compliance with statutes, regulations, and guidelines; negotiating grants; providing consultation and technical assistance to grantees; and administering grants after award.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="grants-process">Grants Process</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">Go to <a href="http://grants.nih.gov/grants/grants_process.htm">Grants Process Overview</a>.</div></div> </div> <div class="views-group-title col-12"> <h2>H</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="health-professional-school-or-college">Health Professional School or College</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><p> In the context of NIH's <a href="https://grants.nih.gov/grants/funding/r15.htm">R15</a> program, health professional schools and colleges are accredited institutions that provide education and training leading to a health professional degree, including but not limited to: BSN, MSN, DNP, MD, DDS, DO, PharmD, DVM, OD, DPT, DC, ND, DPM, MOT, OTD, DPT, BME, MSEE, MS-SLP, CScD, SLPD, AuD, MSPO, MSAT, and MPH. Eligible health professional schools/colleges may include schools or colleges of nursing, medicine, dentistry, osteopathy, pharmacy, veterinary medicine, public health, optometry, allied health, chiropractic, naturopathy, podiatry, rehabilitation medicine, physical therapy, orthotics &amp; prosthetics, kinesiology, biomedical engineering, occupational therapy and psychology. Accreditation must be provided by a body approved for such purpose by the Secretary of Education. </p></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="high-risk/high-impact-(hr/hi)">High Risk/High Impact (HR/HI)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">A category of applications identified by a scientific review group as having a high degree of uncertainty in approach but also a high potential for impact. NIH tracks how many of these applications are identified and funded.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="human-subject">Human Subject</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">A living individual about whom an investigator (whether professional or student) conducting research obtains data through intervention or interaction with the individual or obtains identifiable private information. Regulations governing the use of human subjects in research extend to use of human organs, tissues, and body fluids from identifiable individuals as human subjects and to graphic, written, or recorded information derived from such individuals. (See <a href="http://grants.nih.gov/grants/policy/nihgps/HTML5/section_4/4.1_public_policy_requirements_and_objectives.htm#Human3">Public Policy Requirements and Objectives-Human Subjects Protections</a>).</div></div> </div> <div class="views-group-title col-12"> <h2>I</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="independent-clinical-trial">Independent Clinical Trial</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><p> An independent clinical trial is one for which the researcher proposing the study has primary or lead responsibility for conducting and executing the trial. NIH policy permits individual career development awardees and individuals appointed to institutional career development awards to be involved in a range of clinical trial activities, including leading independent clinical trials. For NRSA trainees or fellows, however, NIH policy precludes leading an independent clinical trial as part of their training experience. Instead, NRSA trainees and fellows interested in clinical trials may gain clinical trial research experience by working on a trial led by their mentor or another investigator. </p></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="institute-or-center-(ic)">Institute or Center (IC)</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><p> The NIH organizational component responsible for a particular grant program or set of activities. The terms "NIH IC" or "awarding IC" are used throughout this document to designate a point of contact for advice and interpretation of grant requirements and to establish the focal point for requesting necessary prior approvals or changes in the terms and conditions of award. </p> <div class="table-responsive"><table class="table"> <thead> <tr> <th> <strong>Acronym</strong> </th> <th> <strong>Full Name</strong> </th> <th> <strong>Organizational Code</strong> </th> </tr> </thead> <tbody> <tr> <td> CC </td> <td> <a href="http://clinicalcenter.nih.gov/">Clinical Center</a> </td> <td> CC </td> </tr> <tr> <td> CSR </td> <td> <a href="http://www.drg.nih.gov/">Center for Scientific Review</a> </td> <td> RG </td> </tr> <tr> <td> CIT </td> <td> <a href="http://www.cit.nih.gov/">Center for Information Technology</a> </td> <td> CIT </td> </tr> <tr> <td> FIC </td> <td> <a href="http://www.fic.nih.gov/">John E. Fogarty International Center </a> </td> <td> TW </td> </tr> <tr> <td> NCATS </td> <td> <a href="http://ncats.nih.gov/">National Center for Advancing Translational Sciences (NCATS)</a> </td> <td> TR </td> </tr> <tr> <td> NCCIH </td> <td> <a href="http://nccih.nih.gov/">National Center for Complementary and Integrative Health</a> </td> <td> AT </td> </tr> <tr> <td> NCI </td> <td> <a href="http://www.nci.nih.gov/">National Cancer Institute</a> </td> <td> CA </td> </tr> <tr> <td> NCRR </td> <td> National Center for Research Resources (dissolved 12/2011) </td> <td> RR </td> </tr> <tr> <td> NEI </td> <td> <a href="http://www.nei.nih.gov/">National Eye Institute</a> </td> <td> EY </td> </tr> <tr> <td> NHGRI </td> <td> <a href="http://www.nhgri.nih.gov/">National Human Genome Research Institute</a> </td> <td> HG </td> </tr> <tr> <td> NHLBI </td> <td> <a href="http://www.nhlbi.nih.gov/index.htm">National Heart, Lung, and Blood Institute</a> </td> <td> HL </td> </tr> <tr> <td> NIA </td> <td> <a href="https://www.nia.nih.gov/">National Institute on Aging</a> </td> <td> AG </td> </tr> <tr> <td> NIAAA </td> <td> <a href="http://www.niaaa.nih.gov/">National Institute on Alcohol Abuse and Alcoholism</a> </td> <td> AA </td> </tr> <tr> <td> NIAID </td> <td> <a href="http://www.niaid.nih.gov/">National Institute of Allergy and Infectious Diseases</a> </td> <td> AI </td> </tr> <tr> <td> NIAMS </td> <td> <a href="http://www.nih.gov/niams/">National Institute of Arthritis and Musculoskeletal and Skin Diseases</a> </td> <td> AR </td> </tr> <tr> <td> NIBIB </td> <td> <a href="http://www.nibib.nih.gov/">National Institute of Biomedical Imaging and Bioengineering</a> </td> <td> EB </td> </tr> <tr> <td> NICHD </td> <td> <em>Eunice Kennedy Shriver </em><a href="http://www.nichd.nih.gov/">National Institute of Child Health and Human Development</a> </td> <td> HD </td> </tr> <tr> <td> NIDA </td> <td> <a href="http://www.nida.nih.gov/">National Institute on Drug Abuse</a> </td> <td> DA </td> </tr> <tr> <td> NIDCD </td> <td> <a href="http://www.nidcd.nih.gov/">National Institute on Deafness and Other Communication Disorders</a> </td> <td> DC </td> </tr> <tr> <td> NIDCR </td> <td> <a href="http://www.nidcr.nih.gov/">National Institute of Dental and Craniofacial Research</a> </td> <td> DE </td> </tr> <tr> <td> NIDDK </td> <td> <a href="http://www.niddk.nih.gov/">National Institute of Diabetes and Digestive and Kidney Diseases</a> </td> <td> DK </td> </tr> <tr> <td> NIEHS </td> <td> <a href="http://www.niehs.nih.gov/">National Institute of Environmental Health Sciences</a> </td> <td> ES </td> </tr> <tr> <td> NIGMS </td> <td> <a href="http://www.nigms.nih.gov/">National Institute of General Medical Sciences</a> </td> <td> GM </td> </tr> <tr> <td> NIMH </td> <td> <a href="http://www.nimh.nih.gov/">National Institute of Mental Health</a> </td> <td> MH </td> </tr> <tr> <td> NIMHD </td> <td> <a href="https://www.nimhd.nih.gov/">National Institute on Minority Health and Health Disparities</a> </td> <td> MD </td> </tr> <tr> <td> NINDS </td> <td> <a href="http://www.ninds.nih.gov/">National Institute of Neurological Disorders and Stroke</a> </td> <td> NS </td> </tr> <tr> <td> NINR </td> <td> <a href="http://www.nih.gov/ninr/">National Institute of Nursing Research</a> </td> <td> NR </td> </tr> <tr> <td> NLM </td> <td> <a href="http://www.nlm.nih.gov/">National Library of Medicine</a> </td> <td> LM </td> </tr> <tr> <td> OD </td> <td> <a href="http://www.nih.gov/icd/od/index.htm">Office of the Director</a> </td> <td> OD </td> </tr> </tbody> </table></div></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="intramural-research">Intramural Research</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">Research conducted by, or in support of, employees of the NIH.</div></div> </div> <div class="views-group-title col-12"> <h2>N</h2> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nci">NCI</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Cancer Institute</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="ncrr">NCRR</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Center for Research Resources (dissolved 12/2011)</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="ned">NED</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH Enterprise Directory</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nei">NEI</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Eye Institute</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nhgri">NHGRI</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><a href="http://www.genome.gov/">NIH National Human Genome Research Institute</a></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nhlbi">NHLBI</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><a href="http://www.nhlbi.nih.gov/index.htm">NIH National Heart, Lung, and Blood Institute</a></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nia">NIA</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute on Aging</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="niaaa">NIAAA</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute on Alcohol Abuse and Alcoholism</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="niaid">NIAID</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of Allergy and Infectious Diseases</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="niams">NIAMS</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nibib">NIBIB</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of Biomedical Imaging and Bioengineering</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nida">NIDA</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute on Drug Abuse</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nidcd">NIDCD</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute on Deafness and Other Communication Disorders</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nidcr">NIDCR</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of Dental and Craniofacial Research</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="niddk">NIDDK</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of Diabetes and Digestive and Kidney Diseases</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="niehs">NIEHS</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of Environmental Health Sciences </div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nigms">NIGMS</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of General Medical Sciences</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nih">NIH</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">National Institutes of Health - A Federal agency whose mission is to improve the health of the people of the United States. NIH is a part of the Public Health Service, which is part of the U.S. Department of Health and Human Services. </div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nih-guide-for-grants-and-contracts">NIH Guide for Grants and Contracts</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">The official publication for NIH&#039;s medical and behavioral research grants policies, guidelines and funding opportunities.</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nih-defined-phase-iii-clinical-trial">NIH-Defined Phase III Clinical Trial</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><p> An NIH-defined Phase III clinical trial is a broadly based prospective Phase III clinical investigation, usually involving several hundred or more human subjects, for the purpose of evaluating an experimental intervention in comparison with a standard or controlled intervention or comparing two or more existing treatments. Often the aim of such investigation is to provide evidence leading to a scientific basis for consideration of a change in health policy or standard of care. The definition includes pharmacologic, non-pharmacologic, and behavioral interventions given for disease prevention, prophylaxis, diagnosis, or therapy. Community trials and other population-based intervention trials are also included. </p></div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nih/od">NIH/OD</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">National Institutes of Health, Office of the Director</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nimh">NIMH</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content">NIH National Institute of Mental Health</div></div> </div> <div class="views-row col-12"> <div class="views-field views-field-name"><span class="field-content"> <h3 class="glossary-term" id="nimhd">NIMHD</h3> </span></div><div class="views-field views-field-field-glossary-extended-definiti definition"><div class="field-content"><a href="https://www.nimhd.nih.gov/">NIH National Institute on Minority Health and Health Disparities</a></div></div> </div> </div> <nav aria-label="pagination-heading"> <h4 id="pagination-heading" class="sr-only">Pagination</h4> <ul class="pagination js-pager__items"> <li class="page-item active"> <span class="page-link">1</span> </li> <li class="page-item "> <a href="?title=NIH&amp;page=1" title="" class="page-link">2</a> </li> <li class="pager__item--next"> <a href="?title=NIH&amp;page=1" title="Go to next page" rel="next" class="page-link"> <span aria-hidden="true">Next ›</span> <span class="sr-only">Next page</span> </a> </li> <li class="page-item page-last"> <a href="?title=NIH&amp;page=1" title="Go to last page" class="page-link"> <span aria-hidden="true">Last »</span> <span class="sr-only">Last page</span> </a> </li> </ul> </nav> </div> </div> </div> </div> <div id="block-webform" class="block 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</section> </main> </div> </div> </div> <footer class="site-footer"> <div class="footer-spotlight"> <div class="container"> <div class="row"> <div class="col"> <h2>You Might Also Be Interested In </h2> <section class="region region-footer-spotlight"> <div id="block-footerinteragencypainresearchportfolio" class="block block-block-content block-block-content4b328f81-8270-42b6-8476-b687a3f3c95b"> <div class="content"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><div class="image default drupal-media-object"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <picture> <source srcset="/sites/default/files/styles/full_width_extra_large/public/2020-12/IPRP.png?itok=jstkU1th 1x" media="all and (min-width: 75em)" type="image/png" width="710" height="330"/> <source srcset="/sites/default/files/styles/full_width_/public/2020-12/IPRP.png?itok=HhB0z7fr 1x" media="all and (min-width: 62em) and (max-width: 74.99em)" type="image/png" width="660" height="307"/> <source srcset="/sites/default/files/styles/full_width_medium/public/2020-12/IPRP.png?itok=FjIgoMYa 1x" media="all and (min-width: 48em) and (max-width: 61.99em)" type="image/png" width="480" height="223"/> <source srcset="/sites/default/files/styles/full_width_small/public/2020-12/IPRP.png?itok=D6EFntk3 1x" media="all and (min-width: 34em) and (max-width: 47.99em)" type="image/png" width="440" height="205"/> <img loading="eager" src="/sites/default/files/styles/full_width_small/public/2020-12/IPRP.png?itok=D6EFntk3" width="440" height="205" alt="Interagency Pain Research Portfolio The Federal Government&#039;s Pain Research Database logo" /> </picture> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><h3>Interagency Pain Research Portfolio</h3> <p>The Interagency Pain <a href="/glossary?title=Research+Portfolio" class="glossary-tooltip" data-toggle="tooltip" title="The cohort of grants supported by a given NIH organization.">Research Portfolio</a> database provides information on pain research and training activities supported by the Federal government.</p></div> <div class="field field--name-field-link field--type-link field--label-hidden field__item"><a href="https://paindatabase.nih.gov/">View the IPRP database</a></div> </div> </div> <div id="block-footernationalpainstrategy" class="block block-block-content block-block-content758df7fe-aa88-4cad-b598-de52eb1c2a49"> <div class="content"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><div class="image default drupal-media-object"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <picture> <source srcset="/sites/default/files/styles/full_width_extra_large/public/2020-12/national-pain-strategy-2x_0.png?itok=oTN4BVll 1x" media="all and (min-width: 75em)" type="image/png" width="710" height="330"/> <source srcset="/sites/default/files/styles/full_width_/public/2020-12/national-pain-strategy-2x_0.png?itok=8cziDR7F 1x" media="all and (min-width: 62em) and (max-width: 74.99em)" type="image/png" width="660" height="307"/> <source srcset="/sites/default/files/styles/full_width_medium/public/2020-12/national-pain-strategy-2x_0.png?itok=k_StZVkN 1x" media="all and (min-width: 48em) and (max-width: 61.99em)" type="image/png" width="480" height="223"/> <source srcset="/sites/default/files/styles/full_width_small/public/2020-12/national-pain-strategy-2x_0.png?itok=4407G5dC 1x" media="all and (min-width: 34em) and (max-width: 47.99em)" type="image/png" width="440" height="205"/> <img loading="eager" src="/sites/default/files/styles/full_width_small/public/2020-12/national-pain-strategy-2x_0.png?itok=4407G5dC" width="440" height="205" alt="National Pain Strategy: A Comprehensive Population Health-Level Strategy for Pain banner/logo" /> </picture> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"> <html><body><h3>The National Pain Strategy</h3> <p>The National Pain Strategy (NPS) outlines a coordinated plan for reducing the burden of chronic pain that affects millions of Americans.</p> <div class="home-feature-link">&nbsp;</div> </body> </html></div> <div class="field field--name-field-link field--type-link field--label-hidden field__item"><a href="https://www.iprcc.nih.gov/national-pain-strategy-overview/national-pain-strategy-report">View the National Pain Strategy</a></div> </div> </div> <div id="block-footerfederalpainportfolioanalysis" class="block block-block-content block-block-content2d3847d9-18a4-408d-a544-d63924faec64"> <div class="content"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><div class="image default drupal-media-object"> <div class="field field--name-field-media-image field--type-image field--label-visually_hidden"> <div class="field__label visually-hidden">Image</div> <div class="field__item"> <picture> <source srcset="/sites/default/files/styles/full_width_extra_large/public/2020-12/federal-pain-research-strategy.png?itok=AtHO7lZz 1x" media="all and (min-width: 75em)" type="image/png" width="710" height="330"/> <source srcset="/sites/default/files/styles/full_width_/public/2020-12/federal-pain-research-strategy.png?itok=OQXzuH6i 1x" media="all and (min-width: 62em) and (max-width: 74.99em)" type="image/png" width="660" height="307"/> <source srcset="/sites/default/files/styles/full_width_medium/public/2020-12/federal-pain-research-strategy.png?itok=jth75niJ 1x" media="all and (min-width: 48em) and (max-width: 61.99em)" type="image/png" width="480" height="223"/> <source srcset="/sites/default/files/styles/full_width_small/public/2020-12/federal-pain-research-strategy.png?itok=r4S2837C 1x" media="all and (min-width: 34em) and (max-width: 47.99em)" type="image/png" width="440" height="205"/> <img loading="eager" src="/sites/default/files/styles/full_width_small/public/2020-12/federal-pain-research-strategy.png?itok=r4S2837C" width="440" height="205" alt="Federal Pain Research Strategy logo" /> </picture> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><h3>Federal Pain Research Strategy</h3> <p>The Federal Pain Research Strategy (FPRS) is an effort of the IPRCC and the National Institutes of Health, Office of Pain Policy to oversee development of a long-term strategic plan to advance the federal pain research agenda.</p></div> <div class="field field--name-field-link field--type-link field--label-hidden field__item"><a href="/federal-pain-research-strategy-overview/federal-research-pain-strategy">View Federal Pain Research Strategy Report</a></div> </div> </div> </section> </div> </div> </div> </div> <a id="back-to-top" class="btn btn-default btn-lg" role="button" title="Click to return on the top page" data-toggle="tooltip" data-placement="left"> <i class="fas fa-arrow-up"></i> </a> <div class="site-footer-top"> <div class="d-flex flex-column flex-lg-row justify-content-between align-items-start align-items-lg-center container"> <div><a href="/contact-us">Contact Us</a></div> <div><a href="https://painconsortium.nih.gov">Pain Consortium</a></div> <div><a href="https://list.nih.gov/cgi-bin/wa.exe?SUBED1=NIHPAINCONSORTIUM&A=1">Pain Consortium ListServ</a></div> <div><a href="https://twitter.com/NIHPainResearch?ref_src=twsrc%5Etfw" class="twitter-follow-button"><svg xmlns="http://www.w3.org/2000/svg" class="x-icon" viewBox="0 0 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