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Tom Brown (chemist) - Wikipedia

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.infobox-table>caption{display:table-caption!important}body.skin--responsive .mw-parser-output .infobox-table>tbody{display:table-row-group}body.skin--responsive .mw-parser-output .infobox-table tr{display:table-row!important}body.skin--responsive .mw-parser-output .infobox-table th,body.skin--responsive .mw-parser-output .infobox-table td{padding-left:inherit;padding-right:inherit}}</style><table class="infobox biography vcard"><tbody><tr><th colspan="2" class="infobox-above" style="font-size:125%;"><div class="fn">Tom Brown</div></th></tr><tr><th scope="row" class="infobox-label">Born</th><td class="infobox-data"><span style="display:none"> (<span class="bday">1952-11-10</span>) </span>10 November 1952<span class="noprint ForceAgeToShow"> (age&#160;72)</span><sup id="cite_ref-debretts_5-0" class="reference"><a href="#cite_note-debretts-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup><br /><div style="display:inline" class="birthplace"><a href="/wiki/Barnsley" title="Barnsley">Barnsley</a>, <a href="/wiki/West_Riding_of_Yorkshire" title="West Riding of Yorkshire">West Riding of Yorkshire</a>, England</div></td></tr><tr><th scope="row" class="infobox-label">Nationality</th><td class="infobox-data category">British</td></tr><tr><th scope="row" class="infobox-label">Alma&#160;mater</th><td class="infobox-data"><a href="/wiki/University_of_Bradford" title="University of Bradford">University of Bradford</a></td></tr><tr><th scope="row" class="infobox-label">Known&#160;for</th><td class="infobox-data"><a href="/wiki/DNA_Repair" class="mw-redirect" title="DNA Repair">DNA Repair</a>,<br /><a href="/wiki/Molecular_genetics" title="Molecular genetics">Molecular genetics</a>,<br /> <a href="/wiki/DNA" title="DNA">DNA</a> <a href="/wiki/Click_chemistry" title="Click chemistry">Click chemistry</a>, <a href="/wiki/Primerdesign" title="Primerdesign">Primerdesign</a></td></tr><tr><th scope="row" class="infobox-label">Awards</th><td class="infobox-data"><style data-mw-deduplicate="TemplateStyles:r1126788409">.mw-parser-output .plainlist ol,.mw-parser-output .plainlist ul{line-height:inherit;list-style:none;margin:0;padding:0}.mw-parser-output .plainlist ol li,.mw-parser-output .plainlist ul li{margin-bottom:0}</style><div class="plainlist"> <ul><li><a href="/wiki/Fellow_of_the_Royal_Society_of_Chemistry" title="Fellow of the Royal Society of Chemistry">FRSC</a><sup id="cite_ref-RSC_Award_1-0" class="reference"><a href="#cite_note-RSC_Award-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup></li> <li><a href="/wiki/FRSE" class="mw-redirect" title="FRSE">FRSE</a> (1993)<sup id="cite_ref-FRSE_2-0" class="reference"><a href="#cite_note-FRSE-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup></li> <li><a href="/wiki/Makdougall_Brisbane_Prize" class="mw-redirect" title="Makdougall Brisbane Prize">Makdougall Brisbane Prize</a> (1992)<sup id="cite_ref-RSE_Prize_3-0" class="reference"><a href="#cite_note-RSE_Prize-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup></li> <li><a href="/wiki/List_of_Royal_Society_of_Chemistry_medals_and_awards" title="List of Royal Society of Chemistry medals and awards">RSC Interdisciplinary Award</a>(2009)<sup id="cite_ref-RSC_Award_1-1" class="reference"><a href="#cite_note-RSC_Award-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup></li> <li><a href="/wiki/Chemistry_World" title="Chemistry World">Chemistry World</a> Entrepreneur of the Year(2014)<sup id="cite_ref-RSC_Entrepreneur_Award_4-0" class="reference"><a href="#cite_note-RSC_Entrepreneur_Award-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup></li></ul> </div></td></tr><tr><td colspan="2" class="infobox-full-data"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1257001546"><b>Scientific career</b></td></tr><tr><th scope="row" class="infobox-label">Fields</th><td class="infobox-data category"><a href="/wiki/Chemical_biology" title="Chemical biology">Chemical biology</a>, <a href="/wiki/Nanotechnology" title="Nanotechnology">Nanotechnology</a></td></tr><tr><th scope="row" class="infobox-label">Institutions</th><td class="infobox-data"><a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a><br /><a href="/wiki/University_of_Southampton" title="University of Southampton">University of Southampton</a><br /><a href="/wiki/University_of_Edinburgh" title="University of Edinburgh">University of Edinburgh</a></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Thesis" title="Thesis">Thesis</a></th><td class="infobox-data"><i><a rel="nofollow" class="external text" href="https://ethos.bl.uk/OrderDetails.do?did=4&amp;uin=uk.bl.ethos.480249">The chemistry of some imidazoles.</a></i>&#160;<span style="font-size:97%;">(1979)</span></td></tr><tr><th scope="row" class="infobox-label"><a href="/wiki/Doctoral_advisor" title="Doctoral advisor">Doctoral advisor</a></th><td class="infobox-data">Gordon Shaw</td></tr><tr><th scope="row" class="infobox-label">Other&#160;academic advisors</th><td class="infobox-data"><a href="/wiki/Olga_Kennard" title="Olga Kennard">Olga Kennard</a> <a href="/wiki/OBE" class="mw-redirect" title="OBE">OBE</a> <a href="/wiki/Fellow_of_the_Royal_Society" title="Fellow of the Royal Society">FRS</a></td></tr><tr style="display:none"><td colspan="2"> </td></tr><tr><th scope="row" class="infobox-label">Website</th><td class="infobox-data"><span class="url"><a rel="nofollow" class="external text" href="http://browngroupnucleicacidsresearch.org.uk/">browngroupnucleicacidsresearch<wbr />.org<wbr />.uk</a></span></td></tr></tbody></table> <p><b>Tom Brown</b> <a href="/wiki/Fellow_of_the_Royal_Society_of_Chemistry" title="Fellow of the Royal Society of Chemistry">FRSC</a><sup id="cite_ref-RSC_Award_1-2" class="reference"><a href="#cite_note-RSC_Award-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/FRSE" class="mw-redirect" title="FRSE">FRSE</a><sup id="cite_ref-FRSE_2-1" class="reference"><a href="#cite_note-FRSE-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> (born 10 November 1952) is a British <a href="/wiki/Chemist" title="Chemist">chemist</a>, <a href="/wiki/Biotechnology" title="Biotechnology">biotechnologist</a>, and entrepreneur. He is the Professor of <a href="/wiki/Nucleic_acid" title="Nucleic acid">Nucleic acid</a> chemistry at the <a href="/wiki/Department_of_Chemistry,_University_of_Oxford" title="Department of Chemistry, University of Oxford">Department of Chemistry</a><sup id="cite_ref-Oxford_Chemistry_6-0" class="reference"><a href="#cite_note-Oxford_Chemistry-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup> and Department of <a href="/wiki/Oncology" title="Oncology">Oncology</a><sup id="cite_ref-Oxford_Oncology_7-0" class="reference"><a href="#cite_note-Oxford_Oncology-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> at the <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a>. Currently, he is serving as the President of the <a href="/wiki/Royal_Society_of_Chemistry#Divisions" title="Royal Society of Chemistry">Chemical Biology Interface Division</a> of the <a href="/wiki/Royal_Society_of_Chemistry" title="Royal Society of Chemistry">Royal Society of Chemistry</a>.<sup id="cite_ref-CBID_RSC_8-0" class="reference"><a href="#cite_note-CBID_RSC-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup> He is best known for his contribution in the field of <a href="/wiki/DNA_Repair" class="mw-redirect" title="DNA Repair">DNA Repair</a>,<sup id="cite_ref-nature1_9-0" class="reference"><a href="#cite_note-nature1-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-pnas1_10-0" class="reference"><a href="#cite_note-pnas1-10"><span class="cite-bracket">&#91;</span>10<span class="cite-bracket">&#93;</span></a></sup> <a href="/wiki/DNA" title="DNA">DNA</a> <a href="/wiki/Click_chemistry" title="Click chemistry">Click chemistry</a>,<sup id="cite_ref-physorg_11-0" class="reference"><a href="#cite_note-physorg-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-chemsocrev_12-0" class="reference"><a href="#cite_note-chemsocrev-12"><span class="cite-bracket">&#91;</span>12<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-chemrev_13-0" class="reference"><a href="#cite_note-chemrev-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup> and in the application of <a href="/wiki/Molecular_genetics" title="Molecular genetics">Molecular genetics</a> in forensics and diagnostics.<sup id="cite_ref-newsci_14-0" class="reference"><a href="#cite_note-newsci-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-nar1_15-0" class="reference"><a href="#cite_note-nar1-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-natbio_16-0" class="reference"><a href="#cite_note-natbio-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> </p><p>He co-founded three biotechnology companies: Oswel Research Products, ATDBio, and <a href="/wiki/Primerdesign" title="Primerdesign">Primerdesign</a>.<sup id="cite_ref-ChemistryWorld_17-0" class="reference"><a href="#cite_note-ChemistryWorld-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Bloomberg_18-0" class="reference"><a href="#cite_note-Bloomberg-18"><span class="cite-bracket">&#91;</span>18<span class="cite-bracket">&#93;</span></a></sup> As of January 2016, he is in the board of directors of last two.<sup id="cite_ref-ATDBio_19-0" class="reference"><a href="#cite_note-ATDBio-19"><span class="cite-bracket">&#91;</span>19<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Primerdesign_20-0" class="reference"><a href="#cite_note-Primerdesign-20"><span class="cite-bracket">&#91;</span>20<span class="cite-bracket">&#93;</span></a></sup> </p> <meta property="mw:PageProp/toc" /> <div class="mw-heading mw-heading2"><h2 id="Education_and_career">Education and career</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tom_Brown_(chemist)&amp;action=edit&amp;section=1" title="Edit section: Education and career"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Brown was born in <a href="/wiki/Barnsley" title="Barnsley">Barnsley</a>, <a href="/wiki/West_Riding_of_Yorkshire" title="West Riding of Yorkshire">West Riding of Yorkshire</a>, and attended Broadway Grammar School there. As an undergraduate student, he attended <a href="/wiki/University_of_Bradford" title="University of Bradford">University of Bradford</a> to study chemistry where he obtained his bachelor's degree with first class honours, and was awarded the Griffin and George Prize for being the most outstanding graduate. In 1979, he earned his PhD from the same university, under the supervision of Prof Gordon Shaw. He then carried out his post-doctoral research at the <a href="/wiki/University_of_Nottingham" title="University of Nottingham">University of Nottingham</a> (with Leslie Crombie and Gerry Pattenden), <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a> (with John Jones), and at the <a href="/wiki/University_of_Cambridge" title="University of Cambridge">University of Cambridge</a> (with <a href="/wiki/Olga_Kennard" title="Olga Kennard">Olga Kennard</a> <a href="/wiki/OBE" class="mw-redirect" title="OBE">OBE</a> <a href="/wiki/Fellow_of_the_Royal_Society" title="Fellow of the Royal Society">FRS</a>).<sup id="cite_ref-debretts_5-1" class="reference"><a href="#cite_note-debretts-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-RSC_Entrepreneur_Award_4-1" class="reference"><a href="#cite_note-RSC_Entrepreneur_Award-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup> </p><p>After these post-doctoral stints, he was appointed as a Lecturer at the <a href="/wiki/University_of_Edinburgh" title="University of Edinburgh">University of Edinburgh</a> where he was subsequently promoted to the rank of <a href="/wiki/Reader_(academic_rank)" title="Reader (academic rank)">Reader</a> and then to Professor. In 1995, he moved to the <a href="/wiki/University_of_Southampton" title="University of Southampton">University of Southampton</a> where he worked as a Professor of <a href="/wiki/Chemical_Biology" class="mw-redirect" title="Chemical Biology">Chemical Biology</a>.<sup id="cite_ref-soton_21-0" class="reference"><a href="#cite_note-soton-21"><span class="cite-bracket">&#91;</span>21<span class="cite-bracket">&#93;</span></a></sup> In 2013, Brown again moved, to take up position of the Professor of <a href="/wiki/Nucleic_acid" title="Nucleic acid">Nucleic acid</a> chemistry at the <a href="/wiki/University_of_Oxford" title="University of Oxford">University of Oxford</a> where he now holds a joint position at the Department of Chemistry and Department of Oncology.<sup id="cite_ref-debretts_5-2" class="reference"><a href="#cite_note-debretts-5"><span class="cite-bracket">&#91;</span>5<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-RSC_Entrepreneur_Award_4-2" class="reference"><a href="#cite_note-RSC_Entrepreneur_Award-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Oxford_Chemistry_6-1" class="reference"><a href="#cite_note-Oxford_Chemistry-6"><span class="cite-bracket">&#91;</span>6<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Oxford_Oncology_7-1" class="reference"><a href="#cite_note-Oxford_Oncology-7"><span class="cite-bracket">&#91;</span>7<span class="cite-bracket">&#93;</span></a></sup> In 2014, he was elected as the President of the <a href="/wiki/Royal_Society_of_Chemistry#Divisions" title="Royal Society of Chemistry">Chemical Biology Interface Division</a> of the <a href="/wiki/Royal_Society_of_Chemistry" title="Royal Society of Chemistry">Royal Society of Chemistry</a> for a term of three years.<sup id="cite_ref-CBID_RSC_8-1" class="reference"><a href="#cite_note-CBID_RSC-8"><span class="cite-bracket">&#91;</span>8<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Research">Research</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tom_Brown_(chemist)&amp;action=edit&amp;section=2" title="Edit section: Research"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>In early part of his academic career, Brown studied base-pair mismatch and <a href="/wiki/DNA_repair" title="DNA repair">DNA repair</a>.<sup id="cite_ref-22" class="reference"><a href="#cite_note-22"><span class="cite-bracket">&#91;</span>22<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-23" class="reference"><a href="#cite_note-23"><span class="cite-bracket">&#91;</span>23<span class="cite-bracket">&#93;</span></a></sup> Later he worked on the mutagenic effect of chemically modified DNA bases. In collaboration with <a href="/wiki/Laurence_Pearl" title="Laurence Pearl">Laurence Pearl</a>, he elucidated the structural basis of <a href="/wiki/Base_excision_repair" title="Base excision repair">excision repair</a> by <a href="/wiki/Uracil-DNA_glycosylase" title="Uracil-DNA glycosylase">Uracil-DNA glycosylase</a>.<sup id="cite_ref-nature1_9-1" class="reference"><a href="#cite_note-nature1-9"><span class="cite-bracket">&#91;</span>9<span class="cite-bracket">&#93;</span></a></sup> His group is also well known for rapid mutation analysis and for the application of <a href="/wiki/Molecular_genetics" title="Molecular genetics">Molecular genetics</a> in forensics<sup id="cite_ref-newsci_14-1" class="reference"><a href="#cite_note-newsci-14"><span class="cite-bracket">&#91;</span>14<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-24" class="reference"><a href="#cite_note-24"><span class="cite-bracket">&#91;</span>24<span class="cite-bracket">&#93;</span></a></sup> and diagnostics.<sup id="cite_ref-nar1_15-1" class="reference"><a href="#cite_note-nar1-15"><span class="cite-bracket">&#91;</span>15<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-natbio_16-1" class="reference"><a href="#cite_note-natbio-16"><span class="cite-bracket">&#91;</span>16<span class="cite-bracket">&#93;</span></a></sup> In collaboration with <a href="/wiki/AstraZeneca" title="AstraZeneca">AstraZeneca</a>, they invented <i>Scorpion Primers system</i>, a fluorescence-based <a href="/wiki/Real-time_polymerase_chain_reaction" title="Real-time polymerase chain reaction">real-time PCR</a> method that can identify mutations and <a href="/wiki/Single-nucleotide_polymorphism" title="Single-nucleotide polymorphism">Single-nucleotide polymorphism</a> in human genome.<sup id="cite_ref-25" class="reference"><a href="#cite_note-25"><span class="cite-bracket">&#91;</span>25<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-26" class="reference"><a href="#cite_note-26"><span class="cite-bracket">&#91;</span>26<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-27" class="reference"><a href="#cite_note-27"><span class="cite-bracket">&#91;</span>27<span class="cite-bracket">&#93;</span></a></sup> Most recently, his group is focusing on the <a href="/wiki/Click_chemistry" title="Click chemistry">Click chemistry</a> based chemical modification of DNA and its application in <a href="/wiki/Bionanotechnology" class="mw-redirect" title="Bionanotechnology">bionanotechnology</a> sector.<sup id="cite_ref-physorg_11-1" class="reference"><a href="#cite_note-physorg-11"><span class="cite-bracket">&#91;</span>11<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-chemsocrev_12-1" class="reference"><a href="#cite_note-chemsocrev-12"><span class="cite-bracket">&#91;</span>12<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-chemrev_13-1" class="reference"><a href="#cite_note-chemrev-13"><span class="cite-bracket">&#91;</span>13<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-28" class="reference"><a href="#cite_note-28"><span class="cite-bracket">&#91;</span>28<span class="cite-bracket">&#93;</span></a></sup> </p><p>As of January 2016, Brown has published more than 300 articles in <a href="/wiki/Peer_review" title="Peer review">peer-reviewed</a> journals, with many of his papers appearing in highly selective journals like <a href="/wiki/Nature_(journal)" title="Nature (journal)">Nature</a>, <a href="/wiki/Nature_Biotechnology" title="Nature Biotechnology">Nature Biotechnology</a>, <a href="/wiki/Cell_(journal)" title="Cell (journal)">Cell</a>, <a href="/wiki/Nucleic_Acids_Research" title="Nucleic Acids Research">Nucleic Acids Research</a>, <a href="/wiki/Journal_of_the_American_Chemical_Society" title="Journal of the American Chemical Society">JACS</a>, and <a href="/wiki/Proceedings_of_the_National_Academy_of_Sciences_of_the_United_States_of_America" title="Proceedings of the National Academy of Sciences of the United States of America">PNAS</a>. His papers have been cited over 18,000 times and he has an <a href="/wiki/H-index" title="H-index">h-index</a> 68.<sup id="cite_ref-gs_29-0" class="reference"><a href="#cite_note-gs-29"><span class="cite-bracket">&#91;</span>29<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="Awards_and_honours">Awards and honours</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tom_Brown_(chemist)&amp;action=edit&amp;section=3" title="Edit section: Awards and honours"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>Brown was elected as a <b>fellow</b> of the <a href="/wiki/Royal_Society_of_Chemistry" title="Royal Society of Chemistry">Royal Society of Chemistry</a><sup id="cite_ref-RSC_Award_1-3" class="reference"><a href="#cite_note-RSC_Award-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup> and <a href="/wiki/Royal_Society_of_Edinburgh" title="Royal Society of Edinburgh">Royal Society of Edinburgh</a>.<sup id="cite_ref-FRSE_2-2" class="reference"><a href="#cite_note-FRSE-2"><span class="cite-bracket">&#91;</span>2<span class="cite-bracket">&#93;</span></a></sup> </p><p>Apart from that, he has received the following major honours in recognition of his research work: </p> <ul><li>1992: Brown received <a href="/wiki/Makdougall_Brisbane_Prize" class="mw-redirect" title="Makdougall Brisbane Prize">Makdougall Brisbane Prize</a> from the <a href="/wiki/Royal_Society_of_Edinburgh" title="Royal Society of Edinburgh">Royal Society of Edinburgh</a>.<sup id="cite_ref-RSE_Prize_3-1" class="reference"><a href="#cite_note-RSE_Prize-3"><span class="cite-bracket">&#91;</span>3<span class="cite-bracket">&#93;</span></a></sup></li> <li>1992: Brown was awarded Josef Loschmidt Award by the <a href="/wiki/Royal_Society_of_Chemistry" title="Royal Society of Chemistry">Royal Society of Chemistry</a><sup id="cite_ref-30" class="reference"><a href="#cite_note-30"><span class="cite-bracket">&#91;</span>30<span class="cite-bracket">&#93;</span></a></sup></li> <li>2004: Brown received Leverhulme Trust Senior Research Fellowship from the <a href="/wiki/Royal_Society" title="Royal Society">Royal Society</a>.<sup id="cite_ref-31" class="reference"><a href="#cite_note-31"><span class="cite-bracket">&#91;</span>31<span class="cite-bracket">&#93;</span></a></sup></li> <li>2008: Brown delivered <a href="/wiki/Keynote" title="Keynote">Keynote</a> Lecture at the <a href="/wiki/Molecular_Frontiers_Foundation" title="Molecular Frontiers Foundation">Molecular Frontiers Symposium</a>, in the Institute of Bioengineering and Nanotechnology, <a href="/wiki/Agency_for_Science,_Technology_and_Research" title="Agency for Science, Technology and Research">A*STAR</a>.<sup id="cite_ref-32" class="reference"><a href="#cite_note-32"><span class="cite-bracket">&#91;</span>32<span class="cite-bracket">&#93;</span></a></sup></li> <li>2009: Brown received <a href="/wiki/List_of_Royal_Society_of_Chemistry_medals_and_awards" title="List of Royal Society of Chemistry medals and awards">RSC Interdisciplinary Award</a> from the <a href="/wiki/Royal_Society_of_Chemistry" title="Royal Society of Chemistry">Royal Society of Chemistry</a><sup id="cite_ref-RSC_Award_1-4" class="reference"><a href="#cite_note-RSC_Award-1"><span class="cite-bracket">&#91;</span>1<span class="cite-bracket">&#93;</span></a></sup></li> <li>2014: Brown received <a href="/wiki/Chemistry_World" title="Chemistry World">Chemistry World</a> Entrepreneur of the Year Award.<sup id="cite_ref-RSC_Entrepreneur_Award_4-3" class="reference"><a href="#cite_note-RSC_Entrepreneur_Award-4"><span class="cite-bracket">&#91;</span>4<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-ChemistryWorld_17-1" class="reference"><a href="#cite_note-ChemistryWorld-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup></li> <li>2015: Brown delivered the invited lecture at the <a href="/wiki/Nobel_Prize" title="Nobel Prize">Nobel</a> workshop, organised by the <a href="/wiki/Royal_Swedish_Academy_of_Sciences" title="Royal Swedish Academy of Sciences">Royal Swedish Academy of Sciences</a> and <a href="/wiki/Chalmers_University_of_Technology" title="Chalmers University of Technology">Chalmers</a>.<sup id="cite_ref-33" class="reference"><a href="#cite_note-33"><span class="cite-bracket">&#91;</span>33<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-34" class="reference"><a href="#cite_note-34"><span class="cite-bracket">&#91;</span>34<span class="cite-bracket">&#93;</span></a></sup></li> <li>2015: Brown was awarded MPLS Impact lifetime Award by the <a href="/wiki/Divisions_of_the_University_of_Oxford#Mathematical,_Physical_and_Life_Sciences_Division_(MPLS)" title="Divisions of the University of Oxford">Mathematical, Physical and Life Sciences Division (MPLS)</a> of the University of Oxford<sup id="cite_ref-35" class="reference"><a href="#cite_note-35"><span class="cite-bracket">&#91;</span>35<span class="cite-bracket">&#93;</span></a></sup></li> <li>2016: Brown received the <a href="/wiki/BBSRC" class="mw-redirect" title="BBSRC">BBSRC</a> Commercial Innovator of the Year 2016 award and <a href="/wiki/BBSRC" class="mw-redirect" title="BBSRC">BBSRC</a> Innovator of the Year 2016 award.<sup id="cite_ref-36" class="reference"><a href="#cite_note-36"><span class="cite-bracket">&#91;</span>36<span class="cite-bracket">&#93;</span></a></sup></li></ul> <div class="mw-heading mw-heading2"><h2 id="Companies">Companies</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tom_Brown_(chemist)&amp;action=edit&amp;section=4" title="Edit section: Companies"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <p>While working at the <a href="/wiki/University_of_Edinburgh" title="University of Edinburgh">University of Edinburgh</a>, Brown founded Oswel Research Products (the name 'Oswel' came from "<a href="/wiki/Oligonucleotide_synthesis" title="Oligonucleotide synthesis">Oligonucleotide synthesis</a>" and "<a href="/wiki/Wellcome_Trust" title="Wellcome Trust">Wellcome Trust</a>"), a company which was dedicated to automated DNA synthesis.<sup id="cite_ref-ChemistryWorld_17-2" class="reference"><a href="#cite_note-ChemistryWorld-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup> Later, in 1995, the company moved to Southampton, along with Brown. In the year 1999, when the company had turnover of GBP 2.2&#160;million and a profit of GBP 0.7&#160;million, <a href="/wiki/Eurogentec" title="Eurogentec">Eurogentec</a> acquired Oswel.<sup id="cite_ref-37" class="reference"><a href="#cite_note-37"><span class="cite-bracket">&#91;</span>37<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-38" class="reference"><a href="#cite_note-38"><span class="cite-bracket">&#91;</span>38<span class="cite-bracket">&#93;</span></a></sup> </p><p>In 2004, Brown co-founded (along with two of his <a href="/wiki/University_of_Southampton" title="University of Southampton">University of Southampton</a> colleagues) <a href="/wiki/Primerdesign" title="Primerdesign">Primerdesign</a>, a company which designs and manufactures products for quantitative <a href="/wiki/Real-time_polymerase_chain_reaction" title="Real-time polymerase chain reaction">Real-time polymerase chain reaction</a>.<sup id="cite_ref-39" class="reference"><a href="#cite_note-39"><span class="cite-bracket">&#91;</span>39<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-ChemistryWorld_17-3" class="reference"><a href="#cite_note-ChemistryWorld-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-Primerdesign_20-1" class="reference"><a href="#cite_note-Primerdesign-20"><span class="cite-bracket">&#91;</span>20<span class="cite-bracket">&#93;</span></a></sup> The company is best known for creating rapid <a href="/wiki/Swine_Flu" class="mw-redirect" title="Swine Flu">Swine Flu</a> detection kit in 2009, and for creating a test for the <a href="/wiki/SARS-CoV-2" title="SARS-CoV-2">SARS-CoV-2</a> virus strain in 2020.<sup id="cite_ref-40" class="reference"><a href="#cite_note-40"><span class="cite-bracket">&#91;</span>40<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-41" class="reference"><a href="#cite_note-41"><span class="cite-bracket">&#91;</span>41<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-42" class="reference"><a href="#cite_note-42"><span class="cite-bracket">&#91;</span>42<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-43" class="reference"><a href="#cite_note-43"><span class="cite-bracket">&#91;</span>43<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-44" class="reference"><a href="#cite_note-44"><span class="cite-bracket">&#91;</span>44<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-45" class="reference"><a href="#cite_note-45"><span class="cite-bracket">&#91;</span>45<span class="cite-bracket">&#93;</span></a></sup> </p><p>In 2005, Brown founded ATDBio with an aim to synthesize chemically modified oligonucleotides for technical applications. As of June 2014, this company maintains two different labs at Southampton and Oxford.<sup id="cite_ref-ChemistryWorld_17-4" class="reference"><a href="#cite_note-ChemistryWorld-17"><span class="cite-bracket">&#91;</span>17<span class="cite-bracket">&#93;</span></a></sup><sup id="cite_ref-ATDBio_19-1" class="reference"><a href="#cite_note-ATDBio-19"><span class="cite-bracket">&#91;</span>19<span class="cite-bracket">&#93;</span></a></sup> </p> <div class="mw-heading mw-heading2"><h2 id="References">References</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tom_Brown_(chemist)&amp;action=edit&amp;section=5" title="Edit section: References"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <style data-mw-deduplicate="TemplateStyles:r1239543626">.mw-parser-output .reflist{margin-bottom:0.5em;list-style-type:decimal}@media screen{.mw-parser-output .reflist{font-size:90%}}.mw-parser-output .reflist .references{font-size:100%;margin-bottom:0;list-style-type:inherit}.mw-parser-output .reflist-columns-2{column-width:30em}.mw-parser-output .reflist-columns-3{column-width:25em}.mw-parser-output .reflist-columns{margin-top:0.3em}.mw-parser-output .reflist-columns ol{margin-top:0}.mw-parser-output .reflist-columns li{page-break-inside:avoid;break-inside:avoid-column}.mw-parser-output .reflist-upper-alpha{list-style-type:upper-alpha}.mw-parser-output .reflist-upper-roman{list-style-type:upper-roman}.mw-parser-output .reflist-lower-alpha{list-style-type:lower-alpha}.mw-parser-output .reflist-lower-greek{list-style-type:lower-greek}.mw-parser-output .reflist-lower-roman{list-style-type:lower-roman}</style><div class="reflist"> <div class="mw-references-wrap mw-references-columns"><ol class="references"> <li id="cite_note-RSC_Award-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-RSC_Award_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-RSC_Award_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-RSC_Award_1-2"><sup><i><b>c</b></i></sup></a> <a href="#cite_ref-RSC_Award_1-3"><sup><i><b>d</b></i></sup></a> <a href="#cite_ref-RSC_Award_1-4"><sup><i><b>e</b></i></sup></a></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1238218222">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free.id-lock-free a{background:url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited.id-lock-limited a,.mw-parser-output .id-lock-registration.id-lock-registration a{background:url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription.id-lock-subscription a{background:url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-free a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-limited a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-registration a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .id-lock-subscription a,body:not(.skin-timeless):not(.skin-minerva) .mw-parser-output .cs1-ws-icon a{background-size:contain;padding:0 1em 0 0}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:var(--color-error,#d33)}.mw-parser-output .cs1-visible-error{color:var(--color-error,#d33)}.mw-parser-output .cs1-maint{display:none;color:#085;margin-left:0.3em}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}@media screen{.mw-parser-output .cs1-format{font-size:95%}html.skin-theme-clientpref-night .mw-parser-output .cs1-maint{color:#18911f}}@media screen and (prefers-color-scheme:dark){html.skin-theme-clientpref-os .mw-parser-output .cs1-maint{color:#18911f}}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.rsc.org/ScienceAndTechnology/Awards/InterdisciplinaryPrize/2009winner1.asp">"Interdisciplinary Award 2009 Winner"</a>. <a href="/wiki/Royal_Society_of_Chemistry" title="Royal Society of Chemistry">Royal Society of Chemistry</a><span class="reference-accessdate">. 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Retrieved <span class="nowrap">27 February</span> 2016</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=unknown&amp;rft.btitle=About+Primerdesign&amp;rft.pub=Primerdesign&amp;rft_id=http%3A%2F%2Fwww.primerdesign.co.uk%2Fabout%2Fabout-primerdesign&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ATom+Brown+%28chemist%29" class="Z3988"></span></span> </li> <li id="cite_note-soton-21"><span class="mw-cite-backlink"><b><a href="#cite_ref-soton_21-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite class="citation web cs1"><a rel="nofollow" class="external text" href="http://www.southampton.ac.uk/chemistry/research/staff/tb2.page">"Tom Brown&#160;: Chemistry"</a>. <a href="/wiki/University_of_Southampton" title="University of Southampton">University of Southampton</a><span class="reference-accessdate">. Retrieved <span class="nowrap">4 March</span> 2016</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&amp;rft.genre=unknown&amp;rft.btitle=Tom+Brown+%3A+Chemistry&amp;rft.pub=University+of+Southampton&amp;rft_id=http%3A%2F%2Fwww.southampton.ac.uk%2Fchemistry%2Fresearch%2Fstaff%2Ftb2.page&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ATom+Brown+%28chemist%29" class="Z3988"></span></span> </li> <li id="cite_note-22"><span class="mw-cite-backlink"><b><a href="#cite_ref-22">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1238218222"><cite id="CITEREFBrownKennardKnealeRabinovich1985" class="citation journal cs1">Brown, Tom; Kennard, Olga; Kneale, Geoff; Rabinovich, Dov (13 June 1985). 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Retrieved <span class="nowrap">8 February</span> 2020</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&amp;rft.genre=unknown&amp;rft.jtitle=The+Times&amp;rft.atitle=Novacyt+in+prime+position+with+coronavirus+test&amp;rft_id=https%3A%2F%2Fwww.thetimes.co.uk%2Farticle%2Fuk-listed-biotech-seeks-fast-track-approval-for-virus-test-z03xm556b&amp;rfr_id=info%3Asid%2Fen.wikipedia.org%3ATom+Brown+%28chemist%29" class="Z3988"></span></span> </li> </ol></div></div> <div class="mw-heading mw-heading2"><h2 id="External_links">External links</h2><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=Tom_Brown_(chemist)&amp;action=edit&amp;section=6" title="Edit section: External links"><span>edit</span></a><span class="mw-editsection-bracket">]</span></span></div> <ul><li><a rel="nofollow" class="external text" href="http://research.chem.ox.ac.uk/professor-tom-brown.aspx">Faculty Page on University of Oxford Website</a></li> <li><a rel="nofollow" class="external text" href="http://www.browngroupnucleicacidsresearch.org.uk">Brown Research Group Website</a></li></ul> <div class="navbox-styles"><style data-mw-deduplicate="TemplateStyles:r1129693374">.mw-parser-output .hlist dl,.mw-parser-output .hlist ol,.mw-parser-output .hlist ul{margin:0;padding:0}.mw-parser-output .hlist dd,.mw-parser-output .hlist dt,.mw-parser-output .hlist li{margin:0;display:inline}.mw-parser-output .hlist.inline,.mw-parser-output .hlist.inline dl,.mw-parser-output .hlist.inline ol,.mw-parser-output .hlist.inline ul,.mw-parser-output .hlist dl dl,.mw-parser-output .hlist dl ol,.mw-parser-output .hlist dl ul,.mw-parser-output .hlist ol dl,.mw-parser-output .hlist ol ol,.mw-parser-output .hlist ol ul,.mw-parser-output .hlist ul dl,.mw-parser-output .hlist ul ol,.mw-parser-output .hlist ul ul{display:inline}.mw-parser-output .hlist .mw-empty-li{display:none}.mw-parser-output .hlist dt::after{content:": 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