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The range includes libraries covering a diverse range of research areas and targets, as well as focused libraries for specific targets and drug repurposing.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/compound-libraries" > Explore Compound Libraries </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/research-areas/targeted-protein-degradation/protein-degraders" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/targeted-protein-degradation-hero.png" alt="Targeted protein degradation" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/research-areas/targeted-protein-degradation/protein-degraders" > <h3 class="card_title_htag"> <div><h3>Protein Degraders</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Small molecule protein Degraders (e.g. PROTAC® Degraders) are used to achieve selective knock-down of target proteins by harnessing the ubiquitin-proteasome system and without the requirement for genetic modification of cells. Bio-Techne provides a wide range of Protein Degraders and negative controls to help you investigate your target of interest.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/research-areas/targeted-protein-degradation/protein-degraders" > Browse Protein Degraders </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/small-molecules-and-peptides/lipid-nanoparticles" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/lipids-teaser-frontimg-v3.png" alt="LNP Teaser FrontImg" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/reagents/small-molecules-and-peptides/lipid-nanoparticles" > <h3 class="card_title_htag"> <div><h3>Lipid Nanoparticles (LNPs)</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>LNPs are non-viral drug delivery systems for a wide range of pharmaceutical cargoes, including small molecules, peptides, and nucleic acids, intended for delivery into target cells in vitro<em> </em>or in vivo. Bio-Techne offers all the essential components to help further your LNP research.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/small-molecules-and-peptides/lipid-nanoparticles" > Browse Lipid Nanoparticle Components </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/fluorescent-dyes-probes" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/fluorescent-probes-350x215.jpg" alt="Fluorescent probes and dyes" loading="lazy" > </div> </a> <a class="card_title_link" href="/reagents/fluorescent-dyes-probes" > <h3 class="card_title_htag"> <div><h3>Fluorescent Dyes and Probes</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Fluorescent dyes and probes allow visualization of intracellular structures and individual proteins, and determination of cell types, in live and fixed cells with high sensitivity and selectivity. Our range includes Janelia Fluor<sup>®</sup> Dyes, cytoskeletal and microtubule probes as well as innovative probes for imaging bacteria. </p></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/fluorescent-dyes-probes" > Explore Fluorescent Probes and Dyes </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/reagents/small-molecules-and-peptides/cept-cocktail" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/cept_cocktail_teaser_card.png" alt="Stem Cell Cluster" loading="lazy" > </div> </a> <a class="card_title_link" href="/reagents/small-molecules-and-peptides/cept-cocktail" > <h3 class="card_title_htag"> <div>CEPT Cocktail</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Improve the viability of PSCs with CEPT Cocktail. A combination of 4 small molecules, the CEPT Cocktail enhances cell survival in a wide range of experimental procedures, including routine long-term passaging, single-cell cloning, gene editing, differentiation and cryopreservation of PSCs.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/reagents/small-molecules-and-peptides/cept-cocktail" > Learn About CEPT Cocktail </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="bg-white border rounded flex-column d-flex h-100"> <a href="/applications/electrophysiology/chemogenetics" > <div class="teaser-card-image-crop mb-3"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/electrophysiology_teaser.png" alt="Neurons firing action potentials" loading="lazy" > </div> </a> <a class="card_title_link" href="/applications/electrophysiology/chemogenetics" > <h3 class="card_title_htag"> <div>Chemogenetics</div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Chemogenetic compounds, such as DREADD ligands and PSEMs, act at genetically modified GPCRs and ion channels, respectively. They enable control of neuronal activity, and investigation of downstream signaling pathways, by initiating a signal cascade from a GPCR or opening of an ion channel pore. </p></div> </div> <div class="card-bottom-link"> <div> <a href="/applications/electrophysiology/chemogenetics" > Explore DREADD Ligands and PSEMs </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--_-2-media-to-text mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_indv_media"> <div> <a href="https://www.bio-techne.com/reagents/tr-fret-and-fp-assay-reagents" title="Learn More" > <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/corafluor-emission-spectra.png" alt="CoraFluor emission spectral overlap with common acceptor dyes" loading="lazy" > </a> </div> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_media_to_text:field_header_2_global"> <div><h3>TR-FRET and FP Assay Reagents</h3></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_lg_sngl_frmtd_text_global"> <div><p> </p> <p>TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) and FP (Fluorescence Polarization) assays are widely used in biology and drug discovery to study target engagement. Discover our range of fluorescent probes, including CoraFluor™ terbium cryptate FRET donors, suitable for exploring ligand binding in TR-FRET and FP assays.</p></div> </div> <div class="field_block:paragraph:2_2_media_to_text:field_call_to_action_global"> <a href="/reagents/tr-fret-and-fp-assay-reagents" class="btn btn-primary" type="link"> Learn More </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="Featured New"></a>New Small Molecules & Peptides</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/research-areas/stem-cells" > </a> <a class="card_title_link" href="/research-areas/stem-cells" > <h3 class="card_title_htag"> <div><h3>Reagents in Solution</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>A range of convenient and ready-to-use reagents in solution to save time on your stem cell culture and CGT workflows. Supplied as a sterile-filtered 10 mM solution: </p><ul><li><a href="/p/small-molecules-peptides/chir-99021-in-solution_8170">CHIR 99021 in solution</a> (pre-dissolved in DMSO)</li><li><a href="/p/small-molecules-peptides/ldn-193189-in-solution_8150">LDN 193189 in solution</a> (pre-dissolved in water)</li><li><a href="/p/small-molecules-peptides/y-27632-in-solution_7000">Y-27632 in solution</a> (pre-dissolved in water)</li></ul></div> </div> <div class="card-bottom-link"> <div> <a href="/research-areas/stem-cells" > View all Stem Cell Products </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/p/small-molecules-peptides/sb-24011_8010" > </a> <a class="card_title_link" href="/p/small-molecules-peptides/sb-24011_8010" > <h3 class="card_title_htag"> <div><h3>SB 24011 | 8010</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><ul><li>Inhibitor of STING-TRIM29 interaction</li><li>Increases cellular STING levels</li><li>Co-administration with <a href="/p/small-molecules-peptides/2-3-cgamp-sodium-salt_5945">cGAMP</a> reduces CT26 and B16F10 tumor volumes in syngeneic mice</li></ul></div> </div> <div class="card-bottom-link"> <div> <a href="/p/small-molecules-peptides/sb-24011_8010" > View SB 24011 </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/p/fluorescent-probes-dyes/rna-imaging-probe-1c_8813" > </a> <a class="card_title_link" href="/p/fluorescent-probes-dyes/rna-imaging-probe-1c_8813" > <h3 class="card_title_htag"> <div><h3>RNA Imaging Probe 1c | 8813</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><ul><li>Fluorogenic RNA imaging probe with excellent photostability</li><li>High membrane permeability and strong fluorogenic response on binding RNA</li><li>Compatible with fluorescence lifetime imaging microscopy (FLIM)</li><li>Low cytotoxicity and suitable for live cell imaging </li></ul></div> </div> <div class="card-bottom-link"> <div> <a href="/p/fluorescent-probes-dyes/rna-imaging-probe-1c_8813" > View RNA Imaging Probe 1c </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <section class="paragraph paragraph--type--full-width-banner-with-image mb-4 paragraph--view-mode--default paragraph-background-color--dark"> <div class="banner_background_image" data-bgimage="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/recombinant_protein_banner_3.png" style="background-repeat: no-repeat;"> <div> <div> <div> <div class="paragraph paragraph--type--_-2-text-to-media mb-4 paragraph--view-mode--default"> <div class="container-fluid container-wide"> <div class="layout layout--twocol-section layout--twocol-section--50-50"> <div class="layout__region layout__region--first"> <div class="hero-content-wrap"> <div class="field_block:paragraph:2_2_text_to_media:field_header_2_global"> <div><h2>BromoTag<sup>®</sup> Degrader for Target Exploration and Validation</h2></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_lg_sngl_frmtd_text_global"> <div><p>Exclusive to Bio-Techne</p></div> </div> <div class="field_block:paragraph:2_2_text_to_media:field_call_to_action_global"> <a href="/t/tag-degradation-platforms/small-molecules-peptides" class="btn btn-primary" type="link"> Learn More </a> </div> </div> </div> <div class="layout__region layout__region--second"> <div class="hero-content-wrap"> </div> </div> </div> </div> </div> </div> </div> </div> </div> </section> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="Pharmacology"></a>Browse Products by Pharmacology</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--button-row paragraph--view-mode--default"> <div class="row"> <div class="col"> <div class="list-grid-wrap"> <div class="row"> <div class="col-md-4"> <a href="https://www.tocris.com/pharmacology/enzymes" class="btn btn-primary" type="link"> Enzymes </a> </div> <div class="col-md-4"> <a href="https://www.tocris.com/pharmacology/enzyme-linked-receptors" class="btn btn-primary" type="link"> Enzyme-linked Receptors </a> </div> <div class="col-md-4"> <a href="https://www.tocris.com/pharmacology/7-tm-receptors" class="btn btn-primary" type="link"> G Protein-coupled Receptors </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--button-row paragraph--view-mode--default"> <div class="row"> <div class="col"> <div class="list-grid-wrap"> <div class="row"> <div class="col-md-4"> <a href="https://www.tocris.com/pharmacology/ion-channels" class="btn btn-primary" type="link"> Ion Channels </a> </div> <div class="col-md-4"> <a href="https://www.tocris.com/pharmacology/nuclear-receptors" class="btn btn-primary" type="link"> Nuclear Receptors </a> </div> <div class="col-md-4"> <a 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h-100"> <a href="/resources/literature/angiogenesis-in-cancer-product-guide" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/literature/650x500-bt-literature-angiogenesis_in_cancer_brochure.png" alt="Angiogenesis in Cancer brochure thumbnail" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/angiogenesis-in-cancer-product-guide" > <h3 class="card_title_htag"> <div><h3>Angiogenesis in Cancer Research Product Guide</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Our Angiogenesis in Cancer Product Guide provides a background to angiogenesis in cancer and highlights products that can be used to investigate angiogenesis therapeutic targets.</p><p> </p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/angiogenesis-in-cancer-product-guide" > Download Angiogenesis in Cancer Product Guide </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/literature/alzheimer-disease-poster" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/literature/alzheimers_disease_poster.png" alt="Alzheimer Disease Poster" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/alzheimer-disease-poster" > <h3 class="card_title_htag"> <div><h3>Alzheimer’s Disease Poster</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>This poster provides an overview of some of the molecular and cellular mechanisms of Alzheimer's disease. Download a digital version of the poster or request a printed copy today.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/alzheimer-disease-poster" > Download or Request the Alzheimer's Disease Poster </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/literature/targeted-protein-degradation-research-guide" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/literature/bio-techne-tpd-brochure-thumb.jpg" alt="TPD Brochure FrontImg" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/literature/targeted-protein-degradation-research-guide" > <h3 class="card_title_htag"> <div><h3>Targeted Protein Degradation and Induced Proximity Product Guide</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>This brochure highlights the tools and services available from Bio-Techne to support your Targeted Protein Degradation and Induced Proximity research. Includes products for target validation, Degrader design, validated antibodies, assays for Degrader development, and tools for induced proximity research.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/literature/targeted-protein-degradation-research-guide" > Download TPD and Induced Proximity Product Guide </a> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--individual-button mb-4 paragraph--view-mode--default w-100"> <div class="row"> <div class="col"> <a href="/resources/literature?tid_2%5B151%5D=151" class="btn btn-primary float-left" type="link" > Find More Small Molecule Resources </a> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--section paragraph--view-mode--default mb-4"> <div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="Calculators"></a>Calculators</h2></div> </div> </div> </div> <div> <div class="paragraph paragraph--type--card-paragraph paragraph--view-mode--default card-para-default"> <div class="row card_row"> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/calculators/molarity-calculator" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/molarity-calculator.png" alt="Use our Molarity Calculator to plan your experiment" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/calculators/molarity-calculator" > <h3 class="card_title_htag"> <div><h3>Molarity Calculator</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Calculate the mass, volume or molar concentration required for a solution.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/calculators/molarity-calculator" > Molarity Calculator </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/calculators/dilution-calculator" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/dilution-calculator.png" alt="Use our Dilution Calculator to plan your experiment" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/calculators/dilution-calculator" > <h3 class="card_title_htag"> <div><h3>Dilution Calculator</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Calculate the dilution required to prepare a stock solution.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/calculators/dilution-calculator" > Dilution Calculator </a> </div> </div> </div> </div> </div> <div class="col-md-4"> <div class="h-100"> <div class="d-flex flex-column h-100"> <a href="/resources/calculators/reconstitution-calculator" > <div class="card-img-top text-center mb-3" style="background-repeat: no-repeat; background-color: ; height:200px; width: 100%;"> <div class="teaser-valign-container" style=""> <div class="valign"> <img src="https://resources.bio-techne.com/bio-techne-assets/images/research-areas/reconstitution-calculator.png" alt="Use our Reconstitution Calculator to plan your experiment" loading="lazy" > </div> </div> </div> </a> <a class="card_title_link" href="/resources/calculators/reconstitution-calculator" > <h3 class="card_title_htag"> <div><h3>Reconstitution Calculator</h3></div> </h3> </a> <div class="card_description flex-grow-1"> <div><p>Calculate the volume of solvent required to reconstitute the contents of your vial.</p></div> </div> <div class="card-bottom-link"> <div> <a href="/resources/calculators/reconstitution-calculator" > Reconstitution Calculator </a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--header"> <div> <div><h2><a name="Background"></a>Background Information</h2></div> </div> </div> </div> <div> <div class="paragraph accordion mb-4 paragraph--type--extendable-paragraph paragraph--view-mode--default"> <div class="card-header rounded-top bg-white"> <a class="collapsed" data-toggle="collapse" href="#expPara-about-small-molecules-amp-peptides10" role="button" aria-expanded="false" aria-controls="expPara"> <h5>About Small Molecules & Peptides</h5> </a> </div> <div class="collapse" id="expPara-about-small-molecules-amp-peptides10" aria-expanded="false" aria-controls="expPara"> <div class="card-body p-4"> <br/> <div><p>Small molecules are organic chemical compounds that have biological activity. They may be used in biological and biomedical research to regulate the activity of proteins such as enzymes, ion channels, receptors and transporters. Many commonly prescribed drugs are small molecules, as they are metabolically stable and can be orally active. Small molecules can be designed to be selective, potent, water-soluble and cell permeable, so have many advantages as research tools.</p> <p>Peptides are chains of amino acids linked by amide bonds. Bioactive peptides are found in all living organisms; examples include ghrelin, orexin, vasopressin and neuropeptide S. Endogenous peptides generally consist of the 20 naturally occurring L-amino acids. However, peptides as research tools can also incorporate D-amino acids or <a href="/t/unnatural-amino-acids">unnatural amino acids</a> and can have further chemical modifications.</p> <p>Small molecules and peptides are key tools in biological research as they can be used to modulate or degrade a target of interest to investigate the downstream consequences. Bioactive small molecules and peptides can be categorized according by pharmacological action, e.g. agonists, partial agonists, antagonists, activators, inhibitors and degraders. Our wide range of small molecules includes gold standard <a href="/research-areas/pharmacology">pharmacology</a> tools, as well as <a href="/reagents/fluorescent-dyes-probes">fluorescent dyes and probes</a>, molecular biology tools including <a href="/search?keywords=viral%20transduction%20enhancers">viral transduction enhancers</a> and <a href="/search?keywords=glycan%20detection%20reagents&brand=tocris">glycan detection reagents</a>, and biochemicals, such as buffers and chelators.</p></div> </div> </div> </div> </div> <div> <div class="paragraph accordion mb-4 paragraph--type--extendable-paragraph paragraph--view-mode--default"> <div class="card-header rounded-top bg-white"> <a class="collapsed" data-toggle="collapse" href="#expPara-faqs18" role="button" aria-expanded="false" aria-controls="expPara"> <h5>FAQs</h5> </a> </div> <div class="collapse" id="expPara-faqs18" aria-expanded="false" aria-controls="expPara"> <div class="card-body p-4"> <br/> <div><h4>What are small molecules?</h4> <p>In biological and biomedical research, a small molecule refers to an organic compound that modulates biological activity. Small molecules are generally chemically synthesized, however some small molecules are derived from natural resources, e.g. toxins. As research materials small molecules have advantages; they can be designed to act selectively at a target of interest, and to be potent, water soluble or cell permeable. Many commonly used medicines are small molecules.</p> <p>Small molecules may also be called biochemicals, chemical probes, and compounds.</p> <h4>What are peptides?</h4> <p>Peptides are short sequences of amino acids linked by amide bonds. Numerous endogenous peptides exist in all living organisms where they play a variety of roles, including within the cardiovascular, endocrine and metabolic systems. Peptides may be chemically synthesized, extracted from natural resources or manufactured recombinantly.</p> <h4>Are small molecules drugs?</h4> <p>Yes, many drugs, both clinically prescribed and illicit drugs, are small molecules. The range of small molecules offered by Tocris, a Bio-Techne brand, includes a large range of compounds that are currently approved for use as medicines. Our catalog also contains compounds that may have failed during clinical trial but are still useful research tools, and compounds that were developed to be tools for <em>in vitro</em> and <em>in vivo</em> research.</p> <p><em>Please note that all Bio-Techne products are strictly for use in biomedical research only. They are not intended for human or veterinary use.</em></p></div> </div> </div> </div> </div> <div> <div class="paragraph paragraph--type--freeform mb-4 paragraph--view-mode--default"> <div><p><em>PROTAC</em><em><sup>®</sup></em><em> is a registered trademark of Arvinas Operations, Inc., and is used under license</em>.</p></div> </div> </div> </div> </div> </article> </div> </div> </section> </main> </div> <div id="brandsbar-footer" class="bg-bt-primary"> <div class="container-wide container-fluid text-white"> <div class="row py-5"> <div class="footer-logo col-xl-3 col-lg-auto d-flex"> <img class="brand-bar-footer-logo" src="/themes/custom/bio_techne_global/logo.svg" alt="Bio-techne logo"> </div> <div class="col-xl-9 col-lg-auto"> <p class="ml-xl-4 bt-px_groteskbold footer-tagline">Global Developer, Manufacturer, and Supplier of High-Quality Reagents, Analytical Instruments, and Precision Diagnostics.</p> </div> <div class="included-brands col"> <span class="font-weight-bold mr-3 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