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style="padding-right:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)">The world’s best preclinical neuroscience</p> <p class="has-medium-font-size" style="padding-right:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--40)">For more than 30 years, in collaboration with some of the best partners in the world, <a href="https://atuka.com/research-milestones/" data-type="page" data-id="1274">Atuka’s scientists have continued to advance both knowledge and research techniques</a> in the field of Parkinson’s disease and beyond. </p> </div> </div> <div class="wp-block-group has-global-padding is-layout-constrained wp-container-core-group-is-layout-17 wp-block-group-is-layout-constrained" style="padding-top:var(--wp--preset--spacing--30);padding-right:var(--wp--preset--spacing--40);padding-bottom:var(--wp--preset--spacing--30);padding-left:var(--wp--preset--spacing--40)"> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex" style="padding-top:0;padding-right:0;padding-bottom:0;padding-left:0"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="flex-basis:50%"> <div class="wp-block-group is-layout-flow wp-block-group-is-layout-flow" style="padding-top:var(--wp--preset--spacing--20);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--20);padding-left:var(--wp--preset--spacing--20)"> <p class="has-jacarta-50-color has-text-color has-link-color has-small-font-size wp-elements-da7f8ad6b2b80cac2f5b9cecbba12809">BEHIND THE SCIENCE</p> <div class="wp-block-query alignfull is-layout-flow wp-block-query-is-layout-flow"><ul class="wp-block-post-template is-layout-flow wp-container-core-post-template-is-layout-1 wp-block-post-template-is-layout-flow"><li class="wp-block-post post-1429 post type-post status-publish format-standard has-post-thumbnail hentry category-behind-the-science"> <div style="height:var(--wp--preset--spacing--10)" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group is-vertical is-nowrap is-layout-flex wp-container-core-group-is-layout-5 wp-block-group-is-layout-flex"><figure class="wp-block-post-featured-image"><img fetchpriority="high" decoding="async" width="1280" height="720" src="https://atuka.com/wp-content/uploads/2024/11/1730305195778.png" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" style="border-radius:0px;object-fit:cover;" srcset="https://atuka.com/wp-content/uploads/2024/11/1730305195778.png 1280w, https://atuka.com/wp-content/uploads/2024/11/1730305195778-300x169.png 300w, https://atuka.com/wp-content/uploads/2024/11/1730305195778-1024x576.png 1024w, https://atuka.com/wp-content/uploads/2024/11/1730305195778-768x432.png 768w" sizes="(max-width: 1280px) 100vw, 1280px" /></figure> <h3 class="has-link-color wp-elements-969502d439f94ba61f659ed7cf26586d wp-block-post-title has-text-color has-jacarta-color has-x-large-font-size"><a href="https://atuka.com/highlights-from-neuroscience-2024-advances-in-parkinsons-disease-research/" target="_self" >Highlights from Neuroscience 2024</a></h3> <div class="has-link-color wp-elements-5338d5936f7b36a200cdc8cc08a867ab wp-block-post-excerpt has-text-color has-jacarta-color has-medium-font-size"><p class="wp-block-post-excerpt__excerpt">At the annual summit of the Society for Neuroscience in Chicago, it was clearer than ever that collaboration and advancing technologies are central to moving the field forward. </p></div> <div class="wp-block-template-part"> <div class="wp-block-group is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-group is-content-justification-left is-layout-flex wp-container-core-group-is-layout-3 wp-block-group-is-layout-flex"><div class="wp-block-post-date"><time datetime="2024-11-08T14:31:00+00:00"><a href="https://atuka.com/highlights-from-neuroscience-2024-advances-in-parkinsons-disease-research/">Nov 8, 2024</a></time></div> <p class="has-contrast-2-color has-text-color">—</p> <div class="taxonomy-category wp-block-post-terms"><a href="https://atuka.com/category/behind-the-science/" rel="tag">Behind the Science</a></div></div> </div> </div> <div style="height:24px" aria-hidden="true" class="wp-block-spacer wp-container-content-5"></div> </div> </li><li class="wp-block-post post-1387 post type-post status-publish format-standard has-post-thumbnail hentry category-behind-the-science"> <div style="height:var(--wp--preset--spacing--10)" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group is-vertical is-nowrap is-layout-flex wp-container-core-group-is-layout-8 wp-block-group-is-layout-flex"><figure class="wp-block-post-featured-image"><img decoding="async" width="1397" height="730" src="https://atuka.com/wp-content/uploads/2024/09/20240911_1625333.jpg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" style="border-radius:0px;object-fit:cover;" srcset="https://atuka.com/wp-content/uploads/2024/09/20240911_1625333.jpg 1397w, https://atuka.com/wp-content/uploads/2024/09/20240911_1625333-300x157.jpg 300w, https://atuka.com/wp-content/uploads/2024/09/20240911_1625333-1024x535.jpg 1024w, https://atuka.com/wp-content/uploads/2024/09/20240911_1625333-768x401.jpg 768w" sizes="(max-width: 1397px) 100vw, 1397px" /></figure> <h3 class="has-link-color wp-elements-969502d439f94ba61f659ed7cf26586d wp-block-post-title has-text-color has-jacarta-color has-x-large-font-size"><a href="https://atuka.com/new-frontiers-in-inflammasome-therapeutics-insights-from-the-6th-annual-summit/" target="_self" >New frontiers in inflammasome therapeutics</a></h3> <div class="has-link-color wp-elements-5338d5936f7b36a200cdc8cc08a867ab wp-block-post-excerpt has-text-color has-jacarta-color has-medium-font-size"><p class="wp-block-post-excerpt__excerpt">Insights from Atuka’s recent visit to the 6th Annual Inflammasome Summit in Boston. </p></div> <div class="wp-block-template-part"> <div class="wp-block-group is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-group is-content-justification-left is-layout-flex wp-container-core-group-is-layout-6 wp-block-group-is-layout-flex"><div class="wp-block-post-date"><time datetime="2024-09-24T15:51:55+00:00"><a href="https://atuka.com/new-frontiers-in-inflammasome-therapeutics-insights-from-the-6th-annual-summit/">Sep 24, 2024</a></time></div> <p class="has-contrast-2-color has-text-color">—</p> <div class="taxonomy-category wp-block-post-terms"><a href="https://atuka.com/category/behind-the-science/" rel="tag">Behind the Science</a></div></div> </div> </div> <div style="height:24px" aria-hidden="true" class="wp-block-spacer wp-container-content-6"></div> </div> </li><li class="wp-block-post post-280 post type-post status-publish format-standard has-post-thumbnail hentry category-behind-the-science tag-als tag-round-table"> <div style="height:var(--wp--preset--spacing--10)" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group is-vertical is-nowrap is-layout-flex wp-container-core-group-is-layout-11 wp-block-group-is-layout-flex"><figure class="wp-block-post-featured-image"><img decoding="async" width="1276" height="720" src="https://atuka.com/wp-content/uploads/2024/07/1717080993243-2.jpeg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" style="border-radius:0px;object-fit:cover;" srcset="https://atuka.com/wp-content/uploads/2024/07/1717080993243-2.jpeg 1276w, https://atuka.com/wp-content/uploads/2024/07/1717080993243-2-300x169.jpeg 300w, https://atuka.com/wp-content/uploads/2024/07/1717080993243-2-1024x578.jpeg 1024w, https://atuka.com/wp-content/uploads/2024/07/1717080993243-2-768x433.jpeg 768w" sizes="(max-width: 1276px) 100vw, 1276px" /></figure> <h3 class="has-link-color wp-elements-969502d439f94ba61f659ed7cf26586d wp-block-post-title has-text-color has-jacarta-color has-x-large-font-size"><a href="https://atuka.com/what-the-market-overlooked-in-seeloss-recent-trehalose-study/" target="_self" >What the market overlooked in Seelos’s recent trehalose study</a></h3> <div class="has-link-color wp-elements-5338d5936f7b36a200cdc8cc08a867ab wp-block-post-excerpt has-text-color has-jacarta-color has-medium-font-size"><p class="wp-block-post-excerpt__excerpt">Atuka’s Jonathan Brotchie and Patrick Howson take a deeper look at the top-line results for IV trehalose, an ALS treatment, and see signs of potential for the compound that the market may have missed. </p></div> <div class="wp-block-template-part"> <div class="wp-block-group is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-group is-content-justification-left is-layout-flex wp-container-core-group-is-layout-9 wp-block-group-is-layout-flex"><div class="wp-block-post-date"><time datetime="2024-05-31T18:02:38+00:00"><a href="https://atuka.com/what-the-market-overlooked-in-seeloss-recent-trehalose-study/">May 31, 2024</a></time></div> <p class="has-contrast-2-color has-text-color">—</p> <div class="taxonomy-category wp-block-post-terms"><a href="https://atuka.com/category/behind-the-science/" rel="tag">Behind the Science</a></div></div> </div> </div> <div style="height:24px" aria-hidden="true" class="wp-block-spacer wp-container-content-7"></div> </div> </li><li class="wp-block-post post-288 post type-post status-publish format-standard has-post-thumbnail hentry category-behind-the-science"> <div style="height:var(--wp--preset--spacing--10)" aria-hidden="true" class="wp-block-spacer"></div> <div class="wp-block-group is-vertical is-nowrap is-layout-flex wp-container-core-group-is-layout-14 wp-block-group-is-layout-flex"><figure class="wp-block-post-featured-image"><img loading="lazy" decoding="async" width="1079" height="720" src="https://atuka.com/wp-content/uploads/2024/07/1715356691132.jpeg" class="attachment-post-thumbnail size-post-thumbnail wp-post-image" alt="" style="border-radius:0px;object-fit:cover;" srcset="https://atuka.com/wp-content/uploads/2024/07/1715356691132.jpeg 1079w, https://atuka.com/wp-content/uploads/2024/07/1715356691132-300x200.jpeg 300w, https://atuka.com/wp-content/uploads/2024/07/1715356691132-1024x683.jpeg 1024w, https://atuka.com/wp-content/uploads/2024/07/1715356691132-768x512.jpeg 768w" sizes="(max-width: 1079px) 100vw, 1079px" /></figure> <h3 class="has-link-color wp-elements-969502d439f94ba61f659ed7cf26586d wp-block-post-title has-text-color has-jacarta-color has-x-large-font-size"><a href="https://atuka.com/tavapodon-offers-great-promise-as-a-new-therapeutic-for-parkinsons-disease/" target="_self" >Tavapodon offers great promise as a new therapeutic for Parkinson’s disease</a></h3> <div class="has-link-color wp-elements-5338d5936f7b36a200cdc8cc08a867ab wp-block-post-excerpt has-text-color has-jacarta-color has-medium-font-size"><p class="wp-block-post-excerpt__excerpt">On the encouraging topline results from Cerevel Therapeutics’ Phase III TEMPO-3 trial for tavapadon, a D1/D5 dopamine receptor partial agonist. </p></div> <div class="wp-block-template-part"> <div class="wp-block-group is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-group is-content-justification-left is-layout-flex wp-container-core-group-is-layout-12 wp-block-group-is-layout-flex"><div class="wp-block-post-date"><time datetime="2024-05-10T18:13:00+00:00"><a href="https://atuka.com/tavapodon-offers-great-promise-as-a-new-therapeutic-for-parkinsons-disease/">May 10, 2024</a></time></div> <p class="has-contrast-2-color has-text-color">—</p> <div class="taxonomy-category wp-block-post-terms"><a href="https://atuka.com/category/behind-the-science/" rel="tag">Behind the Science</a></div></div> </div> </div> <div style="height:24px" aria-hidden="true" class="wp-block-spacer wp-container-content-8"></div> </div> </li></ul></div> </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="flex-basis:33.33%"> <div class="wp-block-group animated fadeIn has-bluebell-5-background-color has-background is-vertical is-layout-flex wp-container-core-group-is-layout-16 wp-block-group-is-layout-flex" style="padding-top:var(--wp--preset--spacing--10);padding-right:var(--wp--preset--spacing--20);padding-bottom:var(--wp--preset--spacing--10);padding-left:var(--wp--preset--spacing--20)"> <p class="has-jacarta-50-color has-text-color has-link-color has-small-font-size wp-elements-df3140b3037eb83f6ea35ce182099bd6">WHITE PAPER</p> <figure class="wp-block-image size-large"><a href="https://atuka.com/paper/the-future-of-gene-therapy/"><img loading="lazy" decoding="async" width="790" height="1024" src="https://atuka.com/wp-content/uploads/2024/05/Screenshot-2024-07-11-at-2.30.28 PM-790x1024.png" alt="" class="wp-image-303" srcset="https://atuka.com/wp-content/uploads/2024/05/Screenshot-2024-07-11-at-2.30.28 PM-790x1024.png 790w, https://atuka.com/wp-content/uploads/2024/05/Screenshot-2024-07-11-at-2.30.28 PM-232x300.png 232w, https://atuka.com/wp-content/uploads/2024/05/Screenshot-2024-07-11-at-2.30.28 PM-768x995.png 768w, https://atuka.com/wp-content/uploads/2024/05/Screenshot-2024-07-11-at-2.30.28 PM.png 818w" sizes="(max-width: 790px) 100vw, 790px" /></a></figure> <h4 class="wp-block-heading has-link-color has-x-large-font-size wp-elements-f45dd0b66003621de58875cfb7a26eba"><a href="https://atuka.com/paper/the-future-of-gene-therapy/" data-type="paper" data-id="310">The future of gene therapy from a pre-clinical perspective</a></h4> <p class="has-small-font-size">The potential of gene therapies is finally being realized and these therapies can deliver life-changing treatments for a broad range of disorders. </p> <p class="has-medium-font-size"><span style="text-decoration: underline;">Atuka’s Chief Innovation Officer Dr Patrick A. Howson explores the past, present, and future of gene therapy.</span></p> </div> </div> </div> </div> <div class="wp-block-group alignfull has-tangerine-5-background-color has-background has-global-padding is-layout-constrained wp-container-core-group-is-layout-19 wp-block-group-is-layout-constrained" style="margin-top:0;margin-bottom:0;padding-top:var(--wp--preset--spacing--40);padding-right:var(--wp--preset--spacing--50);padding-bottom:var(--wp--preset--spacing--40);padding-left:var(--wp--preset--spacing--50)"> <h3 class="wp-block-heading alignwide has-xx-large-font-size" style="margin-top:0;margin-bottom:0;line-height:1">Published papers</h3> <p class="i">Atuka’s scientists have been publishing groundbreaking neuroscience research for many decades, often in collaboration with other renowned leaders in our field. The peer-reviewed papers collected below track the evolution of both our ongoing research and the field more broadly. </p> <div class="wp-block-group alignwide is-layout-flow wp-block-group-is-layout-flow"> <div class="wp-block-query alignwide is-layout-flow wp-block-query-is-layout-flow"> <p></p> <ul class="wp-block-post-template is-layout-flow wp-container-core-post-template-is-layout-2 wp-block-post-template-is-layout-flow"><li class="wp-block-post post-1087 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1016/j.neuropharm.2024.109880">Using artificial intelligence to identify drugs for repurposing to treat l-DOPA-induced dyskinesia</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Neuropharmacology</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1016/j.neuropharm.2024.109880">10.1016/j.neuropharm.2024.109880</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2024-05-01T12:00:00+00:00">May 2024</time> / 1 Citation </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Tom H. Johnston, Alix M.B. Lacoste, Paula Ravenscroft, Jin Su, Sahar Tamadon, Mahtab Seifi, Anthony E. Lang, Susan H. Fox, Jonathan M. Brotchie, Naomi P. Visanji</div> </div> </div> </div> </li><li class="wp-block-post post-1089 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1038/s41467-023-43224-z">Brain-to-gut trafficking of alpha-synuclein by CD11c+ cells in a mouse model of Parkinson’s disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Nature Communications</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1038/s41467-023-43224-z">10.1038/s41467-023-43224-z</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2023-11-20T12:00:00+00:00">November 2023</time> / 6 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Rhonda L. McFleder, Anastasiia Makhotkina, Janos Groh, Ursula Keber, Fabian Imdahl, Josefina Peña Mosca, Alina Peteranderl, Jingjing Wu, Sawako Tabuchi, Jan Hoffmann, Ann-Kathrin Karl, Axel Pagenstecher, Jörg Vogel, Andreas Beilhack, James B. Koprich, Jonathan M. Brotchie, Antoine-Emmanuel Saliba, Jens Volkmann, Chi Wang Ip</div> </div> </div> </div> </li><li class="wp-block-post post-1088 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1186/s12974-023-02759-0">Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Journal of Neuroinflammation</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1186/s12974-023-02759-0">10.1186/s12974-023-02759-0</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2023-03-21T12:00:00+00:00">March 2023</time> / 10 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Alexander Grotemeyer, Judith F. Fischer, James B. Koprich, Jonathan M. Brotchie, Robert Blum, Jens Volkmann, Chi Wang Ip</div> </div> </div> </div> </li><li class="wp-block-post post-1058 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1038/s41531-023-00445-9">Alterations in the LRRK2-Rab pathway in urinary extracellular vesicles as Parkinson’s disease and pharmacodynamic biomarkers</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">npj Parkinson’s Disease</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1038/s41531-023-00445-9">10.1038/s41531-023-00445-9</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2023-02-07T12:00:00+00:00">February 2023</time> / 12 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Jean-Marc Taymans, Eugénie Mutez, William Sibran, Laurine Vandewynckel, Claire Deldycke, Séverine Bleuse, Antoine Marchand, Alessia Sarchione, Coline Leghay, Alexandre Kreisler, Clémence Simonin, James Koprich, Guillaume Baille, Luc Defebvre, Kathy Dujardin, Alain Destée, Marie-Christine Chartier-Harlin</div> </div> </div> </div> </li><li class="wp-block-post post-1037 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1186/s12974-022-02685-7">Expansion of regulatory T cells by CD28 superagonistic antibodies attenuates neurodegeneration in A53T-α-synuclein Parkinson’s disease mice</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Journal of Neuroinflammation</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1186/s12974-022-02685-7">10.1186/s12974-022-02685-7</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2022-12-31T12:00:00+00:00">December 2022</time> / 12 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Mohammad Badr, Rhonda L. McFleder, Jingjing Wu, Susanne Knorr, James B. Koprich, Thomas Hünig, Jonathan M. Brotchie, Jens Volkmann, Manfred B. Lutz, Chi Wang Ip</div> </div> </div> </div> </li><li class="wp-block-post post-1064 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1016/j.bbr.2022.113968">Temporal, spatial and molecular pattern of dopaminergic neurodegeneration in the AAV-A53T α-synuclein rat model of Parkinson’s disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Behavioural Brain Research</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1016/j.bbr.2022.113968">10.1016/j.bbr.2022.113968</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2022-08-01T12:00:00+00:00">August 2022</time> / 5 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Thomas Musacchio, Jing Yin, Fabian Kremer, James B. Koprich, Jonathan M. Brotchie, Jens Volkmann, Chi Wang Ip</div> </div> </div> </div> </li><li class="wp-block-post post-1061 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1186/s13550-022-00915-w">Toward in vivo proof of binding of 18F-labeled inhibitor [18F]TRACK to peripheral tropomyosin receptor kinases</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">EJNMMI Research</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1186/s13550-022-00915-w">10.1186/s13550-022-00915-w</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2022-07-30T12:00:00+00:00">July 2022</time> / 1 Citation </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Melinda Wuest, Justin J. Bailey, Jennifer Dufour, Darryl Glubrecht, Vanessa Omana, Tom H. Johnston, Jonathan M. Brotchie, Ralf Schirrmacher</div> </div> </div> </div> </li><li class="wp-block-post post-1091 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1016/j.neuropharm.2022.108998">Special Issue on new therapeutic approaches to Parkinson disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Neuropharmacology</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1016/j.neuropharm.2022.108998">10.1016/j.neuropharm.2022.108998</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2022-05-01T12:00:00+00:00">May 2022</time> / 2 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">S.H. Fox, J.M. Brotchie</div> </div> </div> </div> </li><li class="wp-block-post post-1092 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1007/s12325-022-02097-2">P2B001 (Extended Release Pramipexole and Rasagiline): A New Treatment Option in Development for Parkinson’s Disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Advances in Therapy</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1007/s12325-022-02097-2">10.1007/s12325-022-02097-2</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2022-03-10T12:00:00+00:00">March 2022</time> / 6 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Robert A. Hauser, Nir Giladi, Werner Poewe, Jonathan Brotchie, Hadas Friedman, Sheila Oren, Pninit Litman</div> </div> </div> </div> </li><li class="wp-block-post post-1066 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1016/j.bbi.2022.01.007">Neurodegeneration by α-synuclein-specific T cells in AAV-A53T-α-synuclein Parkinson’s disease mice</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Brain, Behavior, and Immunity</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1016/j.bbi.2022.01.007">10.1016/j.bbi.2022.01.007</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2022-03-01T12:00:00+00:00">March 2022</time> / 41 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Akua A. Karikari, Rhonda L. McFleder, Eliana Ribechini, Robert Blum, Valentin Bruttel, Susanne Knorr, Mona Gehmeyr, Jens Volkmann, Jonathan M. Brotchie, Fadhil Ahsan, Beatrice Haack, Camelia-Maria Monoranu, Ursula Keber, Rima Yeghiazaryan, Axel Pagenstecher, Tobias Heckel, Thorsten Bischler, Jörg Wischhusen, James B. Koprich, Manfred B. Lutz, Chi Wang Ip</div> </div> </div> </div> </li><li class="wp-block-post post-1090 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1038/s41598-022-06832-1">Enhanced firing of locus coeruleus neurons and SK channel dysfunction are conserved in distinct models of prodromal Parkinson’s disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Scientific Reports</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1038/s41598-022-06832-1">10.1038/s41598-022-06832-1</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2022-02-24T12:00:00+00:00">February 2022</time> / 11 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Lina A. Matschke, Marlene A. Komadowski, Annette Stöhr, Bolam Lee, Martin T. Henrich, Markus Griesbach, Susanne Rinné, Fanni F. Geibl, Wei-Hua Chiu, James B. Koprich, Jonathan M. Brotchie, Aytug K. Kiper, Amalia M. Dolga, Wolfgang H. Oertel, Niels Decher</div> </div> </div> </div> </li><li class="wp-block-post post-1093 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1126/sciadv.abd3994">α-Synuclein–induced Kv4 channelopathy in mouse vagal motoneurons drives nonmotor parkinsonian symptoms</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Science Advances</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1126/sciadv.abd3994">10.1126/sciadv.abd3994</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2021-03-12T12:00:00+00:00">March 2021</time> / 12 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Wei-Hua Chiu, Lora Kovacheva, Ruth E. Musgrove, Hadar Arien-Zakay, James B. Koprich, Jonathan M. Brotchie, Rami Yaka, Danny Ben-Zvi, Menachem Hanani, Jochen Roeper, Joshua A. Goldberg</div> </div> </div> </div> </li><li class="wp-block-post post-1045 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1016/j.expneurol.2020.113514">A novel dopamine D3R agonist SK609 with norepinephrine transporter inhibition promotes improvement in cognitive task performance in rodent and non-human primate models of Parkinson’s disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Experimental Neurology</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1016/j.expneurol.2020.113514">10.1016/j.expneurol.2020.113514</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2021-01-01T12:00:00+00:00">January 2021</time> / 19 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Jay S. Schneider, Courtney A. Marshall, Lauren Keibel, Nathaniel W. Snyder, Michael P. Hill, Jonathan M. Brotchie, Tom H. Johnston, Barry D. Waterhouse, Sandhya Kortagere</div> </div> </div> </div> </li><li class="wp-block-post post-1035 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1038/s41531-020-00138-7">Exosome markers of LRRK2 kinase inhibition</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">npj Parkinson’s Disease</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1038/s41531-020-00138-7">10.1038/s41531-020-00138-7</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2020-11-13T12:00:00+00:00">November 2020</time> / 18 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Shijie Wang, Kaela Kelly, Jonathan M. Brotchie, James B. Koprich, Andrew B. West</div> </div> </div> </div> </li><li class="wp-block-post post-1072 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1016/j.parkreldis.2020.08.009">The selective 5-HT1A receptor agonist, NLX-112, exerts anti-dyskinetic effects in MPTP-treated macaques</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Parkinsonism & Related Disorders</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1016/j.parkreldis.2020.08.009">10.1016/j.parkreldis.2020.08.009</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2020-09-01T12:00:00+00:00">September 2020</time> / 21 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">R. Depoortere, T.H. Johnston, S.H. Fox, J.M. Brotchie, A. Newman-Tancredi</div> </div> </div> </div> </li><li class="wp-block-post post-1094 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.3390/cells9040841">The Promise and Challenges of Developing miRNA-Based Therapeutics for Parkinson’s Disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Cells</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.3390/cells9040841">10.3390/cells9040841</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2020-03-31T12:00:00+00:00">March 2020</time> / 49 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Simoneide S. Titze-de-Almeida, Cristina Soto-Sánchez, Eduardo Fernandez, James B. Koprich, Jonathan M. Brotchie, Ricardo Titze-de-Almeida</div> </div> </div> </div> </li><li class="wp-block-post post-1040 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1186/s40478-020-0894-0">Early-onset impairment of the ubiquitin-proteasome system in dopaminergic neurons caused by α-synuclein</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Acta Neuropathologica Communications</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1186/s40478-020-0894-0">10.1186/s40478-020-0894-0</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2020-02-14T12:00:00+00:00">February 2020</time> / 74 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Chris McKinnon, Mitchell L. De Snoo, Elise Gondard, Clemens Neudorfer, Hien Chau, Sophie G. Ngana, Darren M. O’Hara, Jonathan M. Brotchie, James B. Koprich, Andres M. Lozano, Lorraine V. Kalia, Suneil K. Kalia</div> </div> </div> </div> </li><li class="wp-block-post post-1033 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1002/mds.27962">NYX‐458 Improves Cognitive Performance in a Primate Parkinson’s Disease Model</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Movement Disorders</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1002/mds.27962">10.1002/mds.27962</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2020-01-22T12:00:00+00:00">January 2020</time> / 20 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">A.L Barth, J.S. Schneider, T.H. Johnston, M.P. Hill, J.M. Brotchie, J.R. Moskal, Cassia N. Cearley</div> </div> </div> </div> </li><li class="wp-block-post post-1096 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1038/s41598-019-42847-x">GM1 Ganglioside Modifies α-Synuclein Toxicity and is Neuroprotective in a Rat α-Synuclein Model of Parkinson’s Disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Scientific Reports</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1038/s41598-019-42847-x">10.1038/s41598-019-42847-x</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2019-06-10T12:00:00+00:00">June 2019</time> / 51 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Jay S. Schneider, Radha Aras, Courtney K. Williams, James B. Koprich, Jonathan M. Brotchie, Vikrant Singh</div> </div> </div> </div> </li><li class="wp-block-post post-1095 resource type-resource status-publish hentry"> <hr class="wp-block-separator has-text-color has-contrast-3-color has-alpha-channel-opacity has-contrast-3-background-color has-background alignwide is-style-wide"/> <p><a target="_blank" href="https://doi.org/10.1124/jpet.118.255695">Beneficial Effects of Trehalose on Striatal Dopaminergic Deficits in Rodent and Primate Models of Synucleinopathy in Parkinson’s Disease</a></p> <div class="wp-block-columns is-layout-flex wp-container-core-columns-is-layout-2 wp-block-columns-is-layout-flex"> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-text-field wp-block-mfb-meta-field-block"> <div class="value">Journal of Pharmacology and Experimental Therapeutics</div> </div> <div style="font-size:10px;" class="is-acf-field is-url-field wp-block-mfb-meta-field-block"> <div class="value"><a target="_blank" href="https://doi.org/10.1124/jpet.118.255695">10.1124/jpet.118.255695</a></div> </div> <div style="font-size:10px;" class="wp-block-post-date"><time datetime="2019-03-27T12:00:00+00:00">March 2019</time> / 19 Citations </div> </div> <div class="wp-block-column is-layout-flow wp-block-column-is-layout-flow" style="font-size:0.8rem"> <div class="is-acf-field is-textarea-field wp-block-mfb-meta-field-block"> <div class="value">Patrick A. Howson, Tom H. Johnston, Paula Ravenscroft, Michael P. Hill, Jin Su, Jonathan M. Brotchie, James B. Koprich</div> </div> </div> </div> </li></ul> <div style="height:var(--wp--preset--spacing--30)" aria-hidden="true" class="wp-block-spacer"></div> <nav class="wp-block-query-pagination is-content-justification-space-between is-layout-flex wp-container-core-query-pagination-is-layout-1 wp-block-query-pagination-is-layout-flex" aria-label="Pagination"> <div class="wp-block-query-pagination-numbers has-medium-font-size"><span aria-current="page" class="page-numbers current">1</span> <a class="page-numbers" href="?query-16-page=2">2</a> <a class="page-numbers" href="?query-16-page=3">3</a> <a class="page-numbers" href="?query-16-page=4">4</a> <a class="page-numbers" href="?query-16-page=5">5</a> <a class="page-numbers" href="?query-16-page=6">6</a> <span class="page-numbers dots">…</span> <a class="page-numbers" href="?query-16-page=11">11</a></div> <a href="/our-science/?query-16-page=2" class="wp-block-query-pagination-next">Next Page<span class='wp-block-query-pagination-next-arrow 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