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Michael Schulder (United States of America) - The 20th Biennial Meeting of the World Society for Stereotactic and Functional Neurosurgery
<!doctype html> <html lang="en"> <head> <meta charset="UTF-8"> <title>Michael Schulder (United States of America) - The 20th Biennial Meeting of the World Society for Stereotactic and Functional Neurosurgery</title> <meta name="viewport" content="width=device-width, initial-scale=1.0, user-scalable=0"/> <meta name="description" content=""/> <meta name="author" content="CTI Meeting Technology"/> <meta property="og:title" content="Michael Schulder (United States of America)"/> <meta property="og:url" content="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/1136"/> <meta property="og:image" content=""/> <link rel="shortcut icon" href="/images/favicon/favicon.ico"> <link rel="apple-touch-icon" sizes="180x180" href="/images/favicon/apple-touch-icon.png?v=wAdaPpJKvx"> <link rel="icon" type="image/png" sizes="32x32" href="/images/favicon/favicon-32x32.png?v=wAdaPpJKvx"> <link rel="icon" type="image/png" sizes="16x16" href="/images/favicon/favicon-16x16.png?v=wAdaPpJKvx"> <link 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class="details"> <div class="property-container"> <div class="card-title person-title"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/1136" class="item-expand-action extended">Michael Schulder<small> (United States of America)</small></a></div> </div> <div class="property-container"> </div> <div class="property-container"> </div> <div class="property-container"> </div> <div class="property-container"> </div> </div> </div> </div> <div> <div class="group-container"> <h4>Moderator of 1 Session</h4> <div class="app-link"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/confcal"><i class="fa fa-calendar"></i> Calendar</a></div> <div class="confcal list-view"> <div class="card item-container session st-1-bg" data-id="11" data-streaming="no" > <div class="card-header"> <div class="label-container"><div class="labels"></div> </div> <div class="expand-labels"><i class="fa fa-angle-double-down" aria-hidden="true"></i></div> <div class="actions hidden-xs"> <button 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PM - 06:15 PM</div> </div> <div class="property-container internal_room"> <div class="info">Room</div> <div class="property">Montreux 2+3</div> </div> <div class="property-container internal_moderators"> <div class="info">Chair(s)</div> <div class="property"><ul class="persons"> <li><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/1136" data-id="1136" class="" >Michael Schulder<small> (United States of America)</small></a></li> <li><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/315" data-id="315" class="" >Basant Raj Pant<small> (Nepal)</small></a></li> </ul> </div> </div> <div class="property-container internal_description"> <div class="info">Session Description</div> <div class="property">17 min\ presentation, plus 3 min of Q&A</div> </div> <div class="property-container cslide_SESSION_ICON"> <div class="info">Session Icon</div> <div class="property"><img src='/global_storage/media/content/wssfn24/property/_CTI_-_new_Ticket_gold.png' alt='Ticket'></div> </div> </div> <div class="additional-materials"> <ul class="nav nav-pills logged"> </ul> <div class="tab-content"> </div> </div> <div class="item-content"></div> </div> </div> </div> </div> <div class="group-container"> <h4>Presenter of 3 Presentations</h4> <div class="app-link"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/confcal"><i class="fa fa-calendar"></i> Calendar</a></div> <div class="confcal list-view"> <div class="card presentation" data-id="588"> <div class="card-header"> <div class="actions hidden-xs"> </div> </div> <div class="card-block"> <h4 class="card-title">Historical aspects of lesioning – From Cooper’s cryo-lesioning to HiFU</h4> <div class="details property-auto-width"> <div class="property-container internal s"> <div class="info">Session Name</div> <div class="property"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/confcal/show/session/11">0220 - Lesioning Procedures in Functional Neurosurgery Workshop <small>(ID 11)</small></a></div> </div> <div class="property-container internal s"> <div class="info">Session Type</div> <div class="property">Pre-Congress Workshops</div> </div> <div class="property-container internal s"> <div class="info">Date</div> <div class="property">09/03/2024</div> </div> <div class="property-container internal s"> <div class="info">Session Time</div> <div class="property">02:00 PM - 06:15 PM</div> </div> <div class="property-container internal s"> <div class="info">Room</div> <div class="property">Montreux 2+3</div> </div> <div class="property-container internal p"> <div class="info">Lecture Time</div> <div class="property">02:00 PM - 02:20 PM</div> </div> <div class="property-container internal p"> <div class="info">Presenter</div> <div class="property"><ul class="persons"> <li><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/1136" data-id="1136" class="" >Michael Schulder<small> (United States of America)</small></a></li> </ul> </div> </div> </div> <div class="item-content"><div class="additional-materials"> <ul class="nav nav-pills logged" data-module='confcal' data-log_entity_id="588" data-log_entity_type_id="25"> </ul> <div class="tab-content"> </div> </div> </div> </div> </div> <div class="card presentation" data-id="843"> <div class="card-header"> <div class="actions hidden-xs"> </div> </div> <div class="card-block"> <h4 class="card-title">The future of radiosurgery</h4> <div class="details property-auto-width"> <div class="property-container internal s"> <div class="info">Session Name</div> <div class="property"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/confcal/show/session/107">0760 - Plenary Session 03 <small>(ID 107)</small></a></div> </div> <div class="property-container internal s"> <div class="info">Session Type</div> <div class="property">Plenary Sessions</div> </div> <div class="property-container internal s"> <div class="info">Date</div> <div class="property">09/06/2024</div> </div> <div class="property-container internal s"> <div class="info">Session Time</div> <div class="property">08:15 AM - 10:35 AM</div> </div> <div class="property-container internal s"> <div class="info">Room</div> <div class="property">Vevey</div> </div> <div class="property-container internal p"> <div class="info">Lecture Time</div> <div class="property">09:15 AM - 09:35 AM</div> </div> <div class="property-container internal p"> <div class="info">Presenter</div> <div class="property"><ul class="persons"> <li><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/1136" data-id="1136" class="" >Michael Schulder<small> (United States of America)</small></a></li> </ul> </div> </div> </div> <div class="item-content"><div class="additional-materials"> <ul class="nav nav-pills logged" data-module='confcal' data-log_entity_id="843" data-log_entity_type_id="25"> </ul> <div class="tab-content"> </div> </div> </div> </div> </div> <div class="card presentation" data-id="304"> <div class="card-header"> <div class="actions hidden-xs"> </div> </div> <div class="card-block"> <h4 class="card-title">IMMUNOTHERAPY IMPROVES LOCAL CONTROL FOR LARGE (>4CC IN VOLUME) LUNG CANCER BRAIN METASTASES COMPARED TO RADIOSURGERY ALONE</h4> <div class="details property-auto-width"> <div class="property-container internal s"> <div class="info">Session Name</div> <div class="property"><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/confcal/show/session/128">0680 - Flash Presentation Session 05: Radiosurgery & Lesions <small>(ID 128)</small></a></div> </div> <div class="property-container internal s"> <div class="info">Session Type</div> <div class="property">Flash Presentations</div> </div> <div class="property-container internal s"> <div class="info">Date</div> <div class="property">09/05/2024</div> </div> <div class="property-container internal s"> <div class="info">Session Time</div> <div class="property">04:40 PM - 05:40 PM</div> </div> <div class="property-container internal s"> <div class="info">Room</div> <div class="property">St. Gallen 1+2</div> </div> <div class="property-container internal p"> <div class="info">Lecture Time</div> <div class="property">05:22 PM - 05:29 PM</div> </div> <div class="property-container internal p"> <div class="info">Presenter</div> <div class="property"><ul class="persons"> <li><a href="https://cslide.ctimeetingtech.com/wssfn24/attendee/person/1136" data-id="1136" class="" >Michael Schulder<small> (United States of America)</small></a></li> </ul> </div> </div> </div> <div class="item-content"><div class="additional-materials"> <ul class="nav nav-pills logged" data-module='confcal' data-log_entity_id="304" data-log_entity_type_id="25"> <li><a data-toggle="pill" href="#presentation-abstract-304586054509" data-log="ATTENDEE_CONFCAL_PRESENTATION_EXPAND_ABSTRACT">Abstract</a></li> </ul> <div class="tab-content"> <div id="presentation-abstract-304586054509" class="tab-pane"> <h4 class="pane-header">Abstract</h4> <div class="abstract"><div class='abstract-section' section-id='0b79795d3efc95b9976c7c5b933afce2'><h4 class='section-title'>Introduction</h4><p>Stereotactic radiosurgery (SRS) is a key pillar of treatment for patients with brain metastases (BM). However, rates of local control are worse for patients with large BMs despite advances in SRS. To this end, immune checkpoint inhibitors (ICIs) may provide synergistic effects when implemented alongside SRS, which may improve tumor local control. However, this paradigm has not been investigated for large BMs. We demonstrate our single-center, retrospective experience with SRS with and without ICI for the treatment of patients having lung and breast cancer BM greater than 4cc in volume.</p></div><div class='abstract-section' section-id='20c51b5f4e9aeb5334c90ff072e6f928'><h4 class='section-title'>Methods</h4><p>Patients who received SRS therapy for the treatment of lung cancer BMs greater than 4cc in volume at Northwell Health between January 2017 and June 2023 were retrospectively identified. Local failure events (LF) and utilization of immunotherapy agents were identified and collected. Rate of local control was compared between the subgroup receiving SRS+ICI compared to SRS alone.</p></div><div class='abstract-section' section-id='fd69c5cf902969e6fb71d043085ddee6'><h4 class='section-title'>Results</h4><p>A total of 155 large lung BMs (in 120 patients) greater than 4cc were identified. Of these, 17 patients (22 BMs) received SRS+ICI. There was no significant difference in the median BM volume (10.8cc for SRS only, 10.9cc for SRS+ICI; p=0.225) between subgroups. There was a significant difference in local control rate between SRS only and SRS+ICI (HR for SRS+ICI: 0.178; p=0.032). Six- and 12-month for LF rates were 6.1% and 8.7% for SRS only, and there were no LF events for patients receiving SRS+ICI.</p></div><div class='abstract-section' section-id='b651e8a99c4375feb982b7c2cad376e9'><h4 class='section-title'>Conclusions</h4><p>We present one of the few studies demonstrating clinical outcomes for SRS+ICI for patients with large lung BMs. ICI provided alongside SRS yields improved rates of local control compared to SRS only. Further investigation will identify optimal timing of ICI therapy relative to SRS and elucidate the molecular mechanisms underlying this synergy.</p></div></div> <a class="nav-pills-collapse" href="#">Hide</a> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div id="footer"> <div class="footer text-center"> <div class="footer_wrapper"> <i class="fa fa-chevron-up" aria-hidden="true" style="display: none;"></i> <p>Programme and Faculty are preliminary and subject to change.<br /> <b><a href="http://www.surveymonkey.com/r/MSHLPYT?c=7647_The 20th Biennial Meeting of the World Society for Stereotactic and Functional Neurosurgery_2024" target="_blank"><span>Give Feedback</span></a></b><br /> <span>© 2024 cSLIDE </span><a href="http://www.ctimeetingtech.com" target="_blank"><span>CTI MEETING TECHNOLOGY</span></a><span>. 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