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CD8</span></div></div></header><div class="site-inner"><div class="content-sidebar-wrap"><main class="content"><article class="post-3379 post type-post status-publish format-standard has-post-thumbnail category-bioprocessing tag-active-release-dynabeads tag-cd4-and-cd8-cells tag-cts-detachable-dynabeads-cd4-and-cd8 entry" aria-label="Boost Cell Therapy Processes with CTS Detachable Dynabeads CD4 and CD8"><header class="entry-header"><h1 class="entry-title">Boost Cell Therapy Processes with CTS Detachable Dynabeads CD4 and CD8</h1> <span class="post-info-author"> By <a href="https://www.thermofisher.com/blog/author/lifeinthelabstaff/" title="Posts by Life in the Lab Staff" rel="author">Life in the Lab Staff</a> </span> <span class="post-info-date"> 09.30.2024 </span> </header><div class="entry-content"><p><a href="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/header-image-dynabeads.jpg"><img decoding="async" class="alignnone wp-image-3472" src="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/header-image-dynabeads-300x196.jpg" alt="Enhance Cell Therapy Development with CTS Detachable Dynabeads CD4 and CD8" width="996" height="651" srcset="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/header-image-dynabeads-300x196.jpg 300w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/header-image-dynabeads-1024x668.jpg 1024w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/header-image-dynabeads-768x501.jpg 768w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/header-image-dynabeads-1536x1002.jpg 1536w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/header-image-dynabeads.jpg 1570w" sizes="(max-width: 996px) 100vw, 996px" /></a></p> <p>Cell therapy has emerged as a promising approach for the treatment of various diseases, including blood cancers and autoimmune disorders. The success of cell therapy heavily relies on the isolation of highly pure and functional T-cells. Our newest innovative technology, <a href="https://www.thermofisher.com/us/en/home/life-science/bioproduction/gibco-bioprocessing/cell-therapy/reagents.html">CTS Detachable Dynabeads CD4 and CD8 magnetic Dynabeads</a>, offers a reliable and scalable solution for T-cell isolation and downstream applications.</p> <h2>Addressing challenges in T-cell isolation</h2> <table style="width: 100%;border: none"> <tbody style="border: none"> <tr style="border: none"> <td style="width: 65%;border: none">One of the key challenges in cell therapy research is obtaining highly pure T-cell sub-populations. The CTS Detachable Dynabeads CD4 and CD8 magnetic Dynabeads are specifically designed to address this issue. With their specific binding properties, these Dynabeads enable efficient isolation of CD4+ and CD8+ T-cells, helping to drive high purity and yield of the desired cell populations. This purity is crucial for downstream applications where the presence of contaminating cells could compromise research outcomes or clinical efficacy.</td> <td style="width: 30%;border: none;text-align: center"><a href="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-4-bottle-1.jpg"><img decoding="async" class="wp-image-3403 aligncenter" src="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-4-bottle-1-300x300.jpg" alt="Dynabeads CD4 " width="224" height="224" srcset="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-4-bottle-1-300x300.jpg 300w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-4-bottle-1-150x150.jpg 150w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-4-bottle-1-80x80.jpg 80w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-4-bottle-1.jpg 400w" sizes="(max-width: 224px) 100vw, 224px" /></a><strong>CTS Detachable Dynabeads CD4</strong></td> </tr> <tr style="border: none"> <td style="border: none"></td> <td style="border: none"></td> </tr> <tr style="border: none"> <td style="width: 65%;border: none">Preserving cell viability and functionality during the isolation process is important for successful cell therapy applications as well as maintaining naïve and early memory phenotype prior to activation. The detachable nature of the CTS Detachable Dynabeads CD4 and CD8 magnetic Dynabeads allow for easy and gentle removal, helping minimizing cell stress and allowing optimal cell viability and functionality. This feature is particularly important for downstream processes such as cell expansion, gene editing, and adoptive cell therapy, where the quality of isolated T-cells directly impacts the success of the therapy.</td> <td style="width: 30%;border: none;text-align: center"><a href="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-8-bottle-1.jpg"><img loading="lazy" decoding="async" class="wp-image-3404" src="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-8-bottle-1-300x300.jpg" alt="Dynabeads CD48" width="224" height="224" srcset="https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-8-bottle-1-300x300.jpg 300w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-8-bottle-1-150x150.jpg 150w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-8-bottle-1-80x80.jpg 80w, https://www.thermofisher.com/blog/life-in-the-lab/wp-content/uploads/sites/10/2024/09/cd-8-bottle-1.jpg 400w" sizes="(max-width: 224px) 100vw, 224px" /></a><strong>CTS Detachable Dynabeads CD8</strong></td> </tr> </tbody> </table> <h2 style="text-align: left">Navigating the complexities</h2> <p>The CTS Detachable Dynabeads CD4 and CD8 products offer innovative solutions for the isolation of highly pure, viable, and functional T-cell sub-populations. With their specific binding, detachable feature, regulatory compliance, scalability, and comprehensive support, these beads are poised to enhance cell therapy research and development. By utilizing these advanced technologies, researchers and clinicians can unlock the full potential of T-cell-based therapies, ultimately improving patient outcomes and transforming the landscape of modern medicine.</p> <p>We understand that navigating the complexities of cell therapy research and process development can be challenging. That is why Thermo Fisher Scientific provides comprehensive technical support for our customers. This includes <a href="https://www.thermofisher.com/us/en/home/life-science/bioproduction/gibco-bioprocessing/cell-therapy/reagents.html">application notes</a>, <a href="https://assets.thermofisher.com/TFS-Assets/BPD/Technical-Notes/quantification-residual-magnetic-beads-technical-note.pdf" target="_blank" rel="noopener">protocols</a>, and access to a team of technical experts who can assist with experimental optimization and troubleshooting. Our goal is to facilitate a seamless integration of the CTS Detachable Dynabeads CD4 and CD8 magnetic Dynabeads into your research or clinical workflow, helping to empower you to achieve your scientific objectives.</p> <p>Learn more about CTS Detachable Dynabeads CD4 and CD8 magnetic Dynabeads and how they can elevate your cell therapy research and applications.</p> <p><button style="font-size: 16px" type="button"><a href="https://www.thermofisher.com/us/en/home/global/forms/bioprocessing/cell-culture-cell-therapy-reagents.html">Contact Us</a></button></p> <aside class="mashsb-container mashsb-main "><div class="mashsb_above_buttons">Share this article </div><div class="mashsb-box"><div class="mashsb-buttons"><a class="mashicon-facebook mash-large mashsb-noshadow" href="https://www.facebook.com/sharer.php?u=https%3A%2F%2Fwww.thermofisher.com%2Fblog%2Flife-in-the-lab%2Fbioprocessing-enhance-cell-therapy-development-cd4-cd8%2F" target="_top" rel="nofollow"><span class="icon"></span><span 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