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class="js-react-on-rails-component" style="display:none" data-component-name="ProfileCheckPaperUpdate" data-props="{}" data-trace="false" data-dom-id="ProfileCheckPaperUpdate-react-component-e72e00ce-9127-40b9-86f8-607d66c2220d"></div> <div id="ProfileCheckPaperUpdate-react-component-e72e00ce-9127-40b9-86f8-607d66c2220d"></div> <div class="DesignSystem"><div class="onsite-ping" id="onsite-ping"></div></div><div class="profile-user-info DesignSystem"><div class="social-profile-container"><div class="left-panel-container"><div class="user-info-component-wrapper"><div class="user-summary-cta-container"><div class="user-summary-container"><div class="social-profile-avatar-container"><img class="profile-avatar u-positionAbsolute" border="0" alt="" src="//a.academia-assets.com/images/s200_no_pic.png" /></div><div class="title-container"><h1 class="ds2-5-heading-sans-serif-sm">Dr. Adriano Brasolin</h1><div class="affiliations-container fake-truncate js-profile-affiliations"><div><a class="u-tcGrayDarker" href="https://unifesp.academia.edu/">Universidade Federal de São Paulo (UNIFESP)</a>, <a class="u-tcGrayDarker" href="https://unifesp.academia.edu/Departments/CIRURGIA_PLASTICA/Documents">CIRURGIA PLASTICA</a>, <span class="u-tcGrayDarker">Faculty Member</span></div></div></div></div><div class="sidebar-cta-container"><button class="ds2-5-button hidden profile-cta-button grow js-profile-follow-button" data-broccoli-component="user-info.follow-button" data-click-track="profile-user-info-follow-button" data-follow-user-fname="Dr. Adriano" data-follow-user-id="98888080" data-follow-user-source="profile_button" data-has-google="false"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">add</span>Follow</button><button class="ds2-5-button hidden profile-cta-button grow js-profile-unfollow-button" data-broccoli-component="user-info.unfollow-button" data-click-track="profile-user-info-unfollow-button" data-unfollow-user-id="98888080"><span class="material-symbols-outlined" style="font-size: 20px" translate="no">done</span>Following</button></div></div><div class="user-stats-container"><a><div class="stat-container js-profile-followers"><p class="label">Followers</p><p class="data">6</p></div></a><a><div class="stat-container js-profile-followees" data-broccoli-component="user-info.followees-count" data-click-track="profile-expand-user-info-following"><p class="label">Following</p><p class="data">1</p></div></a><span><div class="stat-container"><p class="label"><span class="js-profile-total-view-text">Public Views</span></p><p class="data"><span class="js-profile-view-count"></span></p></div></span></div><div class="ri-section"><div class="ri-section-header"><span>Interests</span></div><div class="ri-tags-container"><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="98888080" href="https://www.academia.edu/Documents/in/Consumo_de_crack"><div id="js-react-on-rails-context" style="display:none" data-rails-context="{"inMailer":false,"i18nLocale":"en","i18nDefaultLocale":"en","href":"https://unifesp.academia.edu/DrAdrianoBrasolin","location":"/DrAdrianoBrasolin","scheme":"https","host":"unifesp.academia.edu","port":null,"pathname":"/DrAdrianoBrasolin","search":null,"httpAcceptLanguage":null,"serverSide":false}"></div> <div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Consumo de crack"]}" data-trace="false" data-dom-id="Pill-react-component-abc77153-5e23-4678-8bc7-3d59987ba1be"></div> <div id="Pill-react-component-abc77153-5e23-4678-8bc7-3d59987ba1be"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="98888080" href="https://www.academia.edu/Documents/in/Reconstruction"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Reconstruction"]}" data-trace="false" data-dom-id="Pill-react-component-09587698-9b43-426e-a5c8-ed35c5f6e5c0"></div> <div id="Pill-react-component-09587698-9b43-426e-a5c8-ed35c5f6e5c0"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="98888080" href="https://www.academia.edu/Documents/in/Crack"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Crack"]}" data-trace="false" data-dom-id="Pill-react-component-a1cc67dc-e90a-4c80-bf75-ae3df4301c15"></div> <div id="Pill-react-component-a1cc67dc-e90a-4c80-bf75-ae3df4301c15"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="98888080" href="https://www.academia.edu/Documents/in/Drogas"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Drogas"]}" data-trace="false" data-dom-id="Pill-react-component-d1d8244b-5da7-4ec6-97ce-8b230ecdaf29"></div> <div id="Pill-react-component-d1d8244b-5da7-4ec6-97ce-8b230ecdaf29"></div> </a><a data-click-track="profile-user-info-expand-research-interests" data-has-card-for-ri-list="98888080" href="https://www.academia.edu/Documents/in/Plastic_and_Reconstructive_Surgery"><div class="js-react-on-rails-component" style="display:none" data-component-name="Pill" data-props="{"color":"gray","children":["Plastic and Reconstructive Surgery"]}" data-trace="false" data-dom-id="Pill-react-component-c6c6b98f-36bd-42e1-96d8-03d0eee5fbcd"></div> <div id="Pill-react-component-c6c6b98f-36bd-42e1-96d8-03d0eee5fbcd"></div> </a></div></div></div></div><div class="right-panel-container"><div class="user-content-wrapper"><div class="uploads-container" id="social-redesign-work-container"><div class="upload-header"><h2 class="ds2-5-heading-sans-serif-xs">Uploads</h2></div><div class="documents-container backbone-social-profile-documents" style="width: 100%;"><div class="u-taCenter"></div><div class="profile--tab_content_container js-tab-pane tab-pane active" id="all"><div class="profile--tab_heading_container js-section-heading" data-section="Papers" id="Papers"><h3 class="profile--tab_heading_container">Papers by Dr. Adriano Brasolin</h3></div><div class="js-work-strip profile--work_container" data-work-id="97188871"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188871/Fortro_F%C3%B3rceps_Para_Trocarte"><img alt="Research paper thumbnail of Fortro - Fórceps Para Trocarte" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188871/Fortro_F%C3%B3rceps_Para_Trocarte">Fortro - Fórceps Para Trocarte</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team when used manually. The exit of the trocar by counter-incision may be distant from the surgical incision, increasing the difficulty of the procedure and the time of surgery. Objective: To create a surgical instrument to fasten and aid the passage of the trocar of drains through the tissues. Methods: Search of precedence described devices to aid the passage of drains and comparison with the design of the new device. Description of the main characteristics and functions of the instrument created to fasten the trocar of the drains, and assist in the passage through the tissues. Results: The search for precedence in the INPI, USPTO and Google Patents databases resulted, in the International patent classification, in two devices for the passage of trocars: a deposit in the INPI and WIPO, and another one in the USPTO, but none designed as forceps. Forceps analysis under study compared the pat...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188871"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188871"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188871; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188871]").text(description); $(".js-view-count[data-work-id=97188871]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188871; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188871']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188871, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=97188871]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188871,"title":"Fortro - Fórceps Para Trocarte","translated_title":"","metadata":{"abstract":"Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team when used manually. 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Results: The search for precedence in the INPI, USPTO and Google Patents databases resulted, in the International patent classification, in two devices for the passage of trocars: a deposit in the INPI and WIPO, and another one in the USPTO, but none designed as forceps. Forceps analysis under study compared the pat...","internal_url":"https://www.academia.edu/97188871/Fortro_F%C3%B3rceps_Para_Trocarte","translated_internal_url":"","created_at":"2023-02-19T19:12:26.637-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Fortro_Fórceps_Para_Trocarte","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team when used manually. 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Nesse contexto, é dever do médico estar preparado para um atendimento apropriado, sendo este de caráter primário ou para o encaminhamento às respectivas especialidades, demandando uma noção geral das necessidades que essa população possa ter.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188870"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188870"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188870; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188870]").text(description); $(".js-view-count[data-work-id=97188870]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188870; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188870']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188870, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=97188870]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188870,"title":"Abordagem clínica e cirúrgica de pessoas transgênero: para estudantes de Medicina","translated_title":"","metadata":{"abstract":"A população T é um grupo minoritário formado por pessoas que possuem uma identidade e/ou expressão de gênero diferente do sexo atribuído ao nascimento, o que pode causar um desconforto, um mal-estar, chamado “disforia de gênero”. Nesse contexto, é dever do médico estar preparado para um atendimento apropriado, sendo este de caráter primário ou para o encaminhamento às respectivas especialidades, demandando uma noção geral das necessidades que essa população possa ter.","publisher":"Editorial Casa"},"translated_abstract":"A população T é um grupo minoritário formado por pessoas que possuem uma identidade e/ou expressão de gênero diferente do sexo atribuído ao nascimento, o que pode causar um desconforto, um mal-estar, chamado “disforia de gênero”. 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Evidence from literature" class="work-thumbnail" src="https://attachments.academia-assets.com/98879506/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188869/Mammoplasty_steps_for_safe_surgery_Evidence_from_literature">Mammoplasty: steps for safe surgery. Evidence from literature</a></div><div class="wp-workCard_item"><span>Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Conflitos de interesse: não há. Artigo Especial Mamoplastia redutora: passos para uma cirurgia se...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Conflitos de interesse: não há. Artigo Especial Mamoplastia redutora: passos para uma cirurgia segura 367</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0ea8c9c3920e79936859b50eef634fcd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879506,"asset_id":97188869,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879506/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188869"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188869"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188869; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188869]").text(description); $(".js-view-count[data-work-id=97188869]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188869; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188869']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188869, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0ea8c9c3920e79936859b50eef634fcd" } } $('.js-work-strip[data-work-id=97188869]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188869,"title":"Mammoplasty: steps for safe surgery. Evidence from literature","translated_title":"","metadata":{"publisher":"GN1 Genesis Network","grobid_abstract":"Conflitos de interesse: não há. Artigo Especial Mamoplastia redutora: passos para uma cirurgia segura 367","publication_date":{"day":null,"month":null,"year":2021,"errors":{}},"publication_name":"Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery","grobid_abstract_attachment_id":98879506},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188869/Mammoplasty_steps_for_safe_surgery_Evidence_from_literature","translated_internal_url":"","created_at":"2023-02-19T19:12:26.378-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879506,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879506/thumbnails/1.jpg","file_name":"v36n3a21.pdf","download_url":"https://www.academia.edu/attachments/98879506/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Mammoplasty_steps_for_safe_surgery_Evide.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879506/v36n3a21-libre.pdf?1676863995=\u0026response-content-disposition=attachment%3B+filename%3DMammoplasty_steps_for_safe_surgery_Evide.pdf\u0026Expires=1733907619\u0026Signature=RzUmXf2Gr~fh0dwne-EdIfLc9aKvrlZBmEmzzlBVwMUBYzwd~tWFc1-vsbs-ZbC~WDC-2DpUUVR4ME-WpPSPxfaezyCwnoSBs9poQ-VVGkumtVHvzM28Zdi4keJl~~rEdXWFkhhPWO6NydXyvownXSyreG--yNNYFoiwF4jNHAtbL~vQiSVcqubT23c9jkY4hpK9UI7AM6zBa6Lj7-oPhn2~64WCuasnr8U2FYEV8EsCnRuNDnkF23hILiB9dZ9tdeTGHHLKxiuHw7yQEBHPUZ4HUsvPiflt98IeF5LUn6Tq8Aiy0Hc3Ml18zBC-yZIj5EvVBuXpEWWL9LzmACSzVA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Mammoplasty_steps_for_safe_surgery_Evidence_from_literature","translated_slug":"","page_count":7,"language":"pt","content_type":"Work","summary":"Conflitos de interesse: não há. Artigo Especial Mamoplastia redutora: passos para uma cirurgia segura 367","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879506,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879506/thumbnails/1.jpg","file_name":"v36n3a21.pdf","download_url":"https://www.academia.edu/attachments/98879506/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Mammoplasty_steps_for_safe_surgery_Evide.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879506/v36n3a21-libre.pdf?1676863995=\u0026response-content-disposition=attachment%3B+filename%3DMammoplasty_steps_for_safe_surgery_Evide.pdf\u0026Expires=1733907619\u0026Signature=RzUmXf2Gr~fh0dwne-EdIfLc9aKvrlZBmEmzzlBVwMUBYzwd~tWFc1-vsbs-ZbC~WDC-2DpUUVR4ME-WpPSPxfaezyCwnoSBs9poQ-VVGkumtVHvzM28Zdi4keJl~~rEdXWFkhhPWO6NydXyvownXSyreG--yNNYFoiwF4jNHAtbL~vQiSVcqubT23c9jkY4hpK9UI7AM6zBa6Lj7-oPhn2~64WCuasnr8U2FYEV8EsCnRuNDnkF23hILiB9dZ9tdeTGHHLKxiuHw7yQEBHPUZ4HUsvPiflt98IeF5LUn6Tq8Aiy0Hc3Ml18zBC-yZIj5EvVBuXpEWWL9LzmACSzVA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1406653,"name":"Mammoplasty","url":"https://www.academia.edu/Documents/in/Mammoplasty"}],"urls":[{"id":29121257,"url":"http://www.rbcp.org.br/detalhe_artigo.asp?id=2997"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188868"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188868/Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants"><img alt="Research paper thumbnail of Influence of postoperative complications on the failure of immediate breast reconstruction with silicone implants" class="work-thumbnail" src="https://attachments.academia-assets.com/98879505/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188868/Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants">Influence of postoperative complications on the failure of immediate breast reconstruction with silicone implants</a></div><div class="wp-workCard_item"><span>Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a si...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a simple method, but can develop complications culminating in implant removal. The aim of this study was to analyze postoperative complications and evaluate their correlation with implant removal. Method: In a period of 4 years, 323 cases of immediate breast reconstruction with silicone implants following total mastectomy were retrospectively studied in the Institut Gustave-Roussy, France. Results: The most frequent complication was lymphocele (34.9%), followed by cutaneous necrosis (22.9%), infection (19.3%), and hematoma (13.3%). Implant removal was more frequent when a surgical complication occurred, and even more frequent when there was more than one type of complication. The most frequent complication leading to implant removal was infection (75.0%). The expander was the implant that had the highest correlation with implant removal. The use of implants with a volume greater than 300 ml was associated with a significantly higher risk of implant removal. Conclusions: 1) The presence of postoperative complications was a risk factor for implant removal. 2) The risk of removal was higher when more than one complication was present. 3) Infection was the main type of complication associated with implant removal. 4) The expander presented a higher risk of complications and implant removal. 5) The use of implants with a volume greater than 300 ml had a greater risk of need for removal.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="36f07bd7933a9c335995a6160a5d58fc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879505,"asset_id":97188868,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879505/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188868"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188868"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188868; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188868]").text(description); $(".js-view-count[data-work-id=97188868]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188868; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188868']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188868, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "36f07bd7933a9c335995a6160a5d58fc" } } $('.js-work-strip[data-work-id=97188868]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188868,"title":"Influence of postoperative complications on the failure of immediate breast reconstruction with silicone implants","translated_title":"","metadata":{"publisher":"GN1 Genesis Network","ai_title_tag":"Postoperative Complications in Immediate Breast Reconstruction","grobid_abstract":"Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a simple method, but can develop complications culminating in implant removal. The aim of this study was to analyze postoperative complications and evaluate their correlation with implant removal. Method: In a period of 4 years, 323 cases of immediate breast reconstruction with silicone implants following total mastectomy were retrospectively studied in the Institut Gustave-Roussy, France. Results: The most frequent complication was lymphocele (34.9%), followed by cutaneous necrosis (22.9%), infection (19.3%), and hematoma (13.3%). Implant removal was more frequent when a surgical complication occurred, and even more frequent when there was more than one type of complication. The most frequent complication leading to implant removal was infection (75.0%). The expander was the implant that had the highest correlation with implant removal. The use of implants with a volume greater than 300 ml was associated with a significantly higher risk of implant removal. Conclusions: 1) The presence of postoperative complications was a risk factor for implant removal. 2) The risk of removal was higher when more than one complication was present. 3) Infection was the main type of complication associated with implant removal. 4) The expander presented a higher risk of complications and implant removal. 5) The use of implants with a volume greater than 300 ml had a greater risk of need for removal.","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery","grobid_abstract_attachment_id":98879505},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188868/Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants","translated_internal_url":"","created_at":"2023-02-19T19:12:26.284-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879505,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879505/thumbnails/1.jpg","file_name":"05b81beaa44a083c3c6348b92c1536b59402.pdf","download_url":"https://www.academia.edu/attachments/98879505/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Influence_of_postoperative_complications.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879505/05b81beaa44a083c3c6348b92c1536b59402-libre.pdf?1676863996=\u0026response-content-disposition=attachment%3B+filename%3DInfluence_of_postoperative_complications.pdf\u0026Expires=1733907619\u0026Signature=eS3r2KpIWEk~ZkOkSrX0ebaawy3bVcCIEAe-yJsiXpJVEmgu5lFw3y~a~UN-VnNsuX2KBfps35eoIX4e~Z1hbw9jJLqyDKsUQWMY8J7pZSEOKqKK3cpdfRgvlYq5-M0dg1HHC046Lg8ybhdeZZH~pE9zwbcCAL644HyZLrxdeIBXOcJQudiy9A20B~gRTxNbKFX71r~-6cRdDvnDlpLC0DBOuRyZrzOuOH7szADzi1AX~~IpW2ZhPznM8rPMTRhdZH1g-JJ3DnZEmfrC-bKE2s7oTUN7NnwPAIwnlWNzDDgMSzVMd64r7F8iu0S2YayzLwJ~YLlCeBoEDGHhJIcqyg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants","translated_slug":"","page_count":8,"language":"en","content_type":"Work","summary":"Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a simple method, but can develop complications culminating in implant removal. The aim of this study was to analyze postoperative complications and evaluate their correlation with implant removal. Method: In a period of 4 years, 323 cases of immediate breast reconstruction with silicone implants following total mastectomy were retrospectively studied in the Institut Gustave-Roussy, France. Results: The most frequent complication was lymphocele (34.9%), followed by cutaneous necrosis (22.9%), infection (19.3%), and hematoma (13.3%). Implant removal was more frequent when a surgical complication occurred, and even more frequent when there was more than one type of complication. The most frequent complication leading to implant removal was infection (75.0%). The expander was the implant that had the highest correlation with implant removal. The use of implants with a volume greater than 300 ml was associated with a significantly higher risk of implant removal. Conclusions: 1) The presence of postoperative complications was a risk factor for implant removal. 2) The risk of removal was higher when more than one complication was present. 3) Infection was the main type of complication associated with implant removal. 4) The expander presented a higher risk of complications and implant removal. 5) The use of implants with a volume greater than 300 ml had a greater risk of need for removal.","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879505,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879505/thumbnails/1.jpg","file_name":"05b81beaa44a083c3c6348b92c1536b59402.pdf","download_url":"https://www.academia.edu/attachments/98879505/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Influence_of_postoperative_complications.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879505/05b81beaa44a083c3c6348b92c1536b59402-libre.pdf?1676863996=\u0026response-content-disposition=attachment%3B+filename%3DInfluence_of_postoperative_complications.pdf\u0026Expires=1733907619\u0026Signature=eS3r2KpIWEk~ZkOkSrX0ebaawy3bVcCIEAe-yJsiXpJVEmgu5lFw3y~a~UN-VnNsuX2KBfps35eoIX4e~Z1hbw9jJLqyDKsUQWMY8J7pZSEOKqKK3cpdfRgvlYq5-M0dg1HHC046Lg8ybhdeZZH~pE9zwbcCAL644HyZLrxdeIBXOcJQudiy9A20B~gRTxNbKFX71r~-6cRdDvnDlpLC0DBOuRyZrzOuOH7szADzi1AX~~IpW2ZhPznM8rPMTRhdZH1g-JJ3DnZEmfrC-bKE2s7oTUN7NnwPAIwnlWNzDDgMSzVMd64r7F8iu0S2YayzLwJ~YLlCeBoEDGHhJIcqyg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":229577,"name":"Silicone","url":"https://www.academia.edu/Documents/in/Silicone"},{"id":1185895,"name":"Breast Reconstruction","url":"https://www.academia.edu/Documents/in/Breast_Reconstruction"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188867"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188867/Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline"><img alt="Research paper thumbnail of Histological modification in TRAM flap in rats treated with pentoxifylline" class="work-thumbnail" src="https://attachments.academia-assets.com/98879510/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188867/Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline">Histological modification in TRAM flap in rats treated with pentoxifylline</a></div><div class="wp-workCard_item"><span>Acta Cirurgica Brasileira</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pent...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS: 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After that, they were submitted to a caudal unipedicle TRAM flap. On the fifth postoperative day, percentages of flap necrosis were determined via the "paper template" method and Tram flap's zone IV skin biopsies were taken for histological analysis. RESULTS: the mean percentage of flap necrosis in group C was 58.7 % and in group P, 31.1 (Wilcoxon test; p = 0.003). Mean capillary vessels number in zone IV's skin in C group was 33.4 and in P group was 71.9 (p=0.008). CONCLUSIONS: Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV).</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b704ab61423a940d82ee739f5f69f21e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879510,"asset_id":97188867,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879510/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188867"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188867"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188867; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188867]").text(description); $(".js-view-count[data-work-id=97188867]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188867; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188867']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188867, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b704ab61423a940d82ee739f5f69f21e" } } $('.js-work-strip[data-work-id=97188867]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188867,"title":"Histological modification in TRAM flap in rats treated with pentoxifylline","translated_title":"","metadata":{"publisher":"FapUNIFESP (SciELO)","grobid_abstract":"To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS: 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After that, they were submitted to a caudal unipedicle TRAM flap. On the fifth postoperative day, percentages of flap necrosis were determined via the \"paper template\" method and Tram flap's zone IV skin biopsies were taken for histological analysis. RESULTS: the mean percentage of flap necrosis in group C was 58.7 % and in group P, 31.1 (Wilcoxon test; p = 0.003). Mean capillary vessels number in zone IV's skin in C group was 33.4 and in P group was 71.9 (p=0.008). CONCLUSIONS: Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV).","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Acta Cirurgica Brasileira","grobid_abstract_attachment_id":98879510},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188867/Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline","translated_internal_url":"","created_at":"2023-02-19T19:12:26.179-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879510,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879510/thumbnails/1.jpg","file_name":"0102-8650-acb-29-s2-00034.pdf","download_url":"https://www.academia.edu/attachments/98879510/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Histological_modification_in_TRAM_flap_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879510/0102-8650-acb-29-s2-00034-libre.pdf?1676863998=\u0026response-content-disposition=attachment%3B+filename%3DHistological_modification_in_TRAM_flap_i.pdf\u0026Expires=1733907619\u0026Signature=WJxp~kAAW0XALn~trDypcIG6DywR4Daj~CDPVEkPclGSldrMMWzsVEjxbs9gK0RKcd3DLtcMwBITlHPz5LZrDhUNHJXT8dE0roH~vmVKAMMRWm50-k2tT6PZxwzCtWrRbhN6YjrOGvkLJlXwG9x1LBcbJvTgHuc4rAj5MKTkdOuecEZQElH2AhXp5UF-7eLKy50yNXdrgE0QXEuOXgK1LnDHPNwHwq7NC2fi2QO5K6HVuIG-GiWcYoOzVwJvk8-QmaJjH70G4yZpgmEWpe7F-lcxqt0drASgCxfYfZYDEHycixwm~L~lRWqN8V~xiouAxIugk9Ay2lgAVlRFDenPrQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline","translated_slug":"","page_count":4,"language":"en","content_type":"Work","summary":"To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS: 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After that, they were submitted to a caudal unipedicle TRAM flap. On the fifth postoperative day, percentages of flap necrosis were determined via the \"paper template\" method and Tram flap's zone IV skin biopsies were taken for histological analysis. RESULTS: the mean percentage of flap necrosis in group C was 58.7 % and in group P, 31.1 (Wilcoxon test; p = 0.003). Mean capillary vessels number in zone IV's skin in C group was 33.4 and in P group was 71.9 (p=0.008). CONCLUSIONS: Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV).","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879510,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879510/thumbnails/1.jpg","file_name":"0102-8650-acb-29-s2-00034.pdf","download_url":"https://www.academia.edu/attachments/98879510/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Histological_modification_in_TRAM_flap_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879510/0102-8650-acb-29-s2-00034-libre.pdf?1676863998=\u0026response-content-disposition=attachment%3B+filename%3DHistological_modification_in_TRAM_flap_i.pdf\u0026Expires=1733907619\u0026Signature=WJxp~kAAW0XALn~trDypcIG6DywR4Daj~CDPVEkPclGSldrMMWzsVEjxbs9gK0RKcd3DLtcMwBITlHPz5LZrDhUNHJXT8dE0roH~vmVKAMMRWm50-k2tT6PZxwzCtWrRbhN6YjrOGvkLJlXwG9x1LBcbJvTgHuc4rAj5MKTkdOuecEZQElH2AhXp5UF-7eLKy50yNXdrgE0QXEuOXgK1LnDHPNwHwq7NC2fi2QO5K6HVuIG-GiWcYoOzVwJvk8-QmaJjH70G4yZpgmEWpe7F-lcxqt0drASgCxfYfZYDEHycixwm~L~lRWqN8V~xiouAxIugk9Ay2lgAVlRFDenPrQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy"},{"id":71421,"name":"Capillaries","url":"https://www.academia.edu/Documents/in/Capillaries"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin"},{"id":235677,"name":"Behavioral Animal Models","url":"https://www.academia.edu/Documents/in/Behavioral_Animal_Models"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":439784,"name":"Saline","url":"https://www.academia.edu/Documents/in/Saline"},{"id":448603,"name":"Necrosis","url":"https://www.academia.edu/Documents/in/Necrosis"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results"},{"id":564879,"name":"Wistar Rats","url":"https://www.academia.edu/Documents/in/Wistar_Rats"},{"id":1996229,"name":"Pentoxifylline","url":"https://www.academia.edu/Documents/in/Pentoxifylline"},{"id":2463495,"name":"Random Allocation","url":"https://www.academia.edu/Documents/in/Random_Allocation"},{"id":3103472,"name":"Rectus Abdominis","url":"https://www.academia.edu/Documents/in/Rectus_Abdominis"},{"id":3696980,"name":"Platelet Aggregation Inhibitors","url":"https://www.academia.edu/Documents/in/Platelet_Aggregation_Inhibitors"},{"id":3724721,"name":"Surgical Flaps","url":"https://www.academia.edu/Documents/in/Surgical_Flaps"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188866"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188866/Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes"><img alt="Research paper thumbnail of Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes" class="work-thumbnail" src="https://attachments.academia-assets.com/98879520/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188866/Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes">Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes</a></div><div class="wp-workCard_item"><span>Neuroscience Letters</span><span>, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In this study, we investigated agents that increased intracellular calcium levels and their corre...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In this study, we investigated agents that increased intracellular calcium levels and their correlation with apoptotic cell death induction. We used rat astrocytes to investigate the increase in cytosolic Ca 2+ (Ca c 2+) and apoptosis induction by drugs that mobilize Ca 2+ from different sources. We observed that thapsigargin (Thap), caffeine (Caff) and FCCP which caused similar increases in Ca c 2+ levels (30-40%), also induced similar apoptotic rates (30-35%). On the other hand, antimycin (Anti), staurosporine (STS) and ethanol (Eth) promoted higher increases in Ca c 2+ (55-65 %) and higher apoptotic rates (55-85%). Eth induced cell death in a concentration-and time-dependent manner. After treatment with Eth plus Caff for 6, 12 and 24 h, these effects were strongly potentiated. Results suggest that there might be a correlation between Ca c 2+ increase and the rate of apoptosis. It is possible that Eth induces cell death by activation of more than one pathway and Ca 2+ might be one of the elements involved. The present work indicates that Ca 2+ can potentiate death by ethanol in rat astrocytes.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7e9e2fe009dc848e407d210f4d5089c6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879520,"asset_id":97188866,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879520/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188866"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188866"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188866; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188866]").text(description); $(".js-view-count[data-work-id=97188866]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188866; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188866']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188866, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7e9e2fe009dc848e407d210f4d5089c6" } } $('.js-work-strip[data-work-id=97188866]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188866,"title":"Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes","translated_title":"","metadata":{"publisher":"Elsevier BV","grobid_abstract":"In this study, we investigated agents that increased intracellular calcium levels and their correlation with apoptotic cell death induction. We used rat astrocytes to investigate the increase in cytosolic Ca 2+ (Ca c 2+) and apoptosis induction by drugs that mobilize Ca 2+ from different sources. We observed that thapsigargin (Thap), caffeine (Caff) and FCCP which caused similar increases in Ca c 2+ levels (30-40%), also induced similar apoptotic rates (30-35%). On the other hand, antimycin (Anti), staurosporine (STS) and ethanol (Eth) promoted higher increases in Ca c 2+ (55-65 %) and higher apoptotic rates (55-85%). Eth induced cell death in a concentration-and time-dependent manner. After treatment with Eth plus Caff for 6, 12 and 24 h, these effects were strongly potentiated. Results suggest that there might be a correlation between Ca c 2+ increase and the rate of apoptosis. It is possible that Eth induces cell death by activation of more than one pathway and Ca 2+ might be one of the elements involved. The present work indicates that Ca 2+ can potentiate death by ethanol in rat astrocytes.","publication_date":{"day":null,"month":null,"year":2006,"errors":{}},"publication_name":"Neuroscience Letters","grobid_abstract_attachment_id":98879520},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188866/Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes","translated_internal_url":"","created_at":"2023-02-19T19:12:26.018-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879520,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879520/thumbnails/1.jpg","file_name":"j.neulet.2005.09.06620230220-1-1alncbk.pdf","download_url":"https://www.academia.edu/attachments/98879520/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptotic_effect_of_ethanol_is_potentiat.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879520/j.neulet.2005.09.06620230220-1-1alncbk-libre.pdf?1676863988=\u0026response-content-disposition=attachment%3B+filename%3DApoptotic_effect_of_ethanol_is_potentiat.pdf\u0026Expires=1733907619\u0026Signature=AZjdoKez0RqjQf0EOWp3g6lqb2W4gkJQmTJbwzAAb~xWfyc51F6lR4f8kd9WcowhzyXZuZjyPEJQ1XotEBLGNgOGE0lFDv71Vks3PwJK6RsTFIE-lXyYcL2OV6fPO~PgyD4yBPK0sh6mUsirnxH-mt0Jw4n8NzFbJcUy78PUPeYR3S5h9K7Rl7IHf8h54M1Jj3Og9dkU1DCy1dQ9nn71lEVUCqVG-ECu5fC3DXpf1TYN9InRL3bvwBY9eT9KDnIipObXkjBKjHEKZ7Q4mBNG0NN6rfViQtDt2tgsNkeS4hGWugrcHGy5gaPx-q5RuJNKs7D3sxgEqkPmu5Lk4Csf0w__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes","translated_slug":"","page_count":5,"language":"en","content_type":"Work","summary":"In this study, we investigated agents that increased intracellular calcium levels and their correlation with apoptotic cell death induction. We used rat astrocytes to investigate the increase in cytosolic Ca 2+ (Ca c 2+) and apoptosis induction by drugs that mobilize Ca 2+ from different sources. We observed that thapsigargin (Thap), caffeine (Caff) and FCCP which caused similar increases in Ca c 2+ levels (30-40%), also induced similar apoptotic rates (30-35%). On the other hand, antimycin (Anti), staurosporine (STS) and ethanol (Eth) promoted higher increases in Ca c 2+ (55-65 %) and higher apoptotic rates (55-85%). Eth induced cell death in a concentration-and time-dependent manner. After treatment with Eth plus Caff for 6, 12 and 24 h, these effects were strongly potentiated. Results suggest that there might be a correlation between Ca c 2+ increase and the rate of apoptosis. It is possible that Eth induces cell death by activation of more than one pathway and Ca 2+ might be one of the elements involved. The present work indicates that Ca 2+ can potentiate death by ethanol in rat astrocytes.","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879520,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879520/thumbnails/1.jpg","file_name":"j.neulet.2005.09.06620230220-1-1alncbk.pdf","download_url":"https://www.academia.edu/attachments/98879520/download_file?st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptotic_effect_of_ethanol_is_potentiat.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879520/j.neulet.2005.09.06620230220-1-1alncbk-libre.pdf?1676863988=\u0026response-content-disposition=attachment%3B+filename%3DApoptotic_effect_of_ethanol_is_potentiat.pdf\u0026Expires=1733907619\u0026Signature=AZjdoKez0RqjQf0EOWp3g6lqb2W4gkJQmTJbwzAAb~xWfyc51F6lR4f8kd9WcowhzyXZuZjyPEJQ1XotEBLGNgOGE0lFDv71Vks3PwJK6RsTFIE-lXyYcL2OV6fPO~PgyD4yBPK0sh6mUsirnxH-mt0Jw4n8NzFbJcUy78PUPeYR3S5h9K7Rl7IHf8h54M1Jj3Og9dkU1DCy1dQ9nn71lEVUCqVG-ECu5fC3DXpf1TYN9InRL3bvwBY9eT9KDnIipObXkjBKjHEKZ7Q4mBNG0NN6rfViQtDt2tgsNkeS4hGWugrcHGy5gaPx-q5RuJNKs7D3sxgEqkPmu5Lk4Csf0w__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science"},{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":9534,"name":"Calcium","url":"https://www.academia.edu/Documents/in/Calcium"},{"id":12981,"name":"Enzyme Inhibitors","url":"https://www.academia.edu/Documents/in/Enzyme_Inhibitors"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":67129,"name":"Caffeine","url":"https://www.academia.edu/Documents/in/Caffeine"},{"id":112576,"name":"Cell Death","url":"https://www.academia.edu/Documents/in/Cell_Death"},{"id":121705,"name":"Ethanol","url":"https://www.academia.edu/Documents/in/Ethanol"},{"id":122187,"name":"Endoplasmic Reticulum","url":"https://www.academia.edu/Documents/in/Endoplasmic_Reticulum"},{"id":130116,"name":"Astrocyte","url":"https://www.academia.edu/Documents/in/Astrocyte"},{"id":196442,"name":"Astrocytes","url":"https://www.academia.edu/Documents/in/Astrocytes"},{"id":891369,"name":"Manganese Compounds","url":"https://www.academia.edu/Documents/in/Manganese_Compounds"},{"id":1599862,"name":"Fura","url":"https://www.academia.edu/Documents/in/Fura"},{"id":1823382,"name":"Intracellular Calcium","url":"https://www.academia.edu/Documents/in/Intracellular_Calcium"},{"id":2260515,"name":"Chlorides","url":"https://www.academia.edu/Documents/in/Chlorides"},{"id":3428040,"name":"Central nervous system stimulants","url":"https://www.academia.edu/Documents/in/Central_nervous_system_stimulants"},{"id":3545627,"name":"Drug synergism","url":"https://www.academia.edu/Documents/in/Drug_synergism"},{"id":3950591,"name":"Antimycin A","url":"https://www.academia.edu/Documents/in/Antimycin_A"}],"urls":[{"id":29121256,"url":"https://api.elsevier.com/content/article/PII:S0304394005011109?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188862"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188862/Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health"><img alt="Research paper thumbnail of Experience Report on Setting Up a Transdisciplinary Outpatient Unit for Transgender Health" class="work-thumbnail" src="https://attachments.academia-assets.com/98879489/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188862/Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health">Experience Report on Setting Up a Transdisciplinary Outpatient Unit for Transgender Health</a></div><div class="wp-workCard_item"><span>The Journal of Sexual Medicine</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction & objectives: Voice is an important gender marker in the transition process as a tra...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction & objectives: Voice is an important gender marker in the transition process as a transgender individual accepts a new gender identity. Perceptive-auditory and acoustic analyses of the voices of these individuals have determined that vocal pitch is one of the most important markers of gender. The aim of this study was to describe and relate aspects of a perceptual-auditory analysis and the fundamental frequency of male-to-female (MPF) transsexual individuals. Population sample: A case-control study was carried out with individuals aged 19 to 52 years who attended the Gender Identity Program of the Hospital de Clínicas of Porto Alegre. Methods: Vocal recordings from the MPF transgender individuals (vowel / a: / and six phrases of Consensus Auditory Perceptual Evaluation Voice (CAPE-V)) were edited and randomly coded before storage in a Dropbox folder. The voices (vowel /a:/) were analyzed by consensus on the same day by two speech-language audiologists who had more than ten years of experience in the voice area using the GRBASI perceptualauditory vocal evaluation scale. Acoustic analysis of the glottic source was performed using the advanced Multi-Dimensional Voice Program software. The resonance focus and the degrees of masculinity and femininity for each voice recording were determined by listening to the CAPE-V phrases. Results: There were significant differences between the groups regarding a greater roughness (discrete degree) (p ¼ 0.031), greater frequency of subjects with F0 between 80e150 Hz (p ¼ 0.003), and a greater frequency of hypernasal resonant focus (p <0.001) in the MPF cases compared with the controls. Conclusion & recommendations: The MPF group of individuals showed greater roughness (discrete degree), altered vertical resonant focus, more masculine voices, and more severe fundamental frequencies than the controls. This information may contribute to better therapy planning and vocal feminization surgery for transgender women.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e41ac712fb3bc5a9925d104c16c044a8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879489,"asset_id":97188862,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879489/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188862"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188862"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188862; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188862]").text(description); $(".js-view-count[data-work-id=97188862]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188862; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188862']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188862, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "e41ac712fb3bc5a9925d104c16c044a8" } } $('.js-work-strip[data-work-id=97188862]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188862,"title":"Experience Report on Setting Up a Transdisciplinary Outpatient Unit for Transgender Health","translated_title":"","metadata":{"publisher":"Oxford University Press (OUP)","grobid_abstract":"Introduction \u0026 objectives: Voice is an important gender marker in the transition process as a transgender individual accepts a new gender identity. Perceptive-auditory and acoustic analyses of the voices of these individuals have determined that vocal pitch is one of the most important markers of gender. The aim of this study was to describe and relate aspects of a perceptual-auditory analysis and the fundamental frequency of male-to-female (MPF) transsexual individuals. Population sample: A case-control study was carried out with individuals aged 19 to 52 years who attended the Gender Identity Program of the Hospital de Clínicas of Porto Alegre. Methods: Vocal recordings from the MPF transgender individuals (vowel / a: / and six phrases of Consensus Auditory Perceptual Evaluation Voice (CAPE-V)) were edited and randomly coded before storage in a Dropbox folder. The voices (vowel /a:/) were analyzed by consensus on the same day by two speech-language audiologists who had more than ten years of experience in the voice area using the GRBASI perceptualauditory vocal evaluation scale. Acoustic analysis of the glottic source was performed using the advanced Multi-Dimensional Voice Program software. The resonance focus and the degrees of masculinity and femininity for each voice recording were determined by listening to the CAPE-V phrases. Results: There were significant differences between the groups regarding a greater roughness (discrete degree) (p ¼ 0.031), greater frequency of subjects with F0 between 80e150 Hz (p ¼ 0.003), and a greater frequency of hypernasal resonant focus (p \u003c0.001) in the MPF cases compared with the controls. Conclusion \u0026 recommendations: The MPF group of individuals showed greater roughness (discrete degree), altered vertical resonant focus, more masculine voices, and more severe fundamental frequencies than the controls. This information may contribute to better therapy planning and vocal feminization surgery for transgender women.","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"The Journal of Sexual Medicine","grobid_abstract_attachment_id":98879489},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188862/Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health","translated_internal_url":"","created_at":"2023-02-19T19:11:55.947-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879489,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879489/thumbnails/1.jpg","file_name":"jsm_14_5_supplement_4_e267.pdf","download_url":"https://www.academia.edu/attachments/98879489/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Experience_Report_on_Setting_Up_a_Transd.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879489/jsm_14_5_supplement_4_e267-libre.pdf?1676863995=\u0026response-content-disposition=attachment%3B+filename%3DExperience_Report_on_Setting_Up_a_Transd.pdf\u0026Expires=1733907619\u0026Signature=HuMJKLLmY3cAvxZ9zmaeGQKcqmJAgsLdMog-KHSQ5HnWK~wxnhmkmkHSU58lNX~xH1Z7aL8Fd18GVXperAVqpHZXRJoWmZ0FwfBgsgyxMcL5xrs8xXBivTnR5ixlsgFleXZATeCnB08YitofxRfNeA0HIzGGnQ2hoYWsGaTbRMgROO4~00RtrQYJ~dV92FxQFU2fYmIYZxdZ0Ra2kCW4-gAsNStXTMvLJxJXnP7gz9p3n4LCJfXsDnlsCk91fosqoJcnmfLIrIdfDaChCz~LTxEuZgXrUw-fsNzVRNSPi-enfqcD9zAGjshOb-UhiCNgAF2m~o4LloEA0hMlPgBYHg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health","translated_slug":"","page_count":1,"language":"en","content_type":"Work","summary":"Introduction \u0026 objectives: Voice is an important gender marker in the transition process as a transgender individual accepts a new gender identity. Perceptive-auditory and acoustic analyses of the voices of these individuals have determined that vocal pitch is one of the most important markers of gender. The aim of this study was to describe and relate aspects of a perceptual-auditory analysis and the fundamental frequency of male-to-female (MPF) transsexual individuals. Population sample: A case-control study was carried out with individuals aged 19 to 52 years who attended the Gender Identity Program of the Hospital de Clínicas of Porto Alegre. Methods: Vocal recordings from the MPF transgender individuals (vowel / a: / and six phrases of Consensus Auditory Perceptual Evaluation Voice (CAPE-V)) were edited and randomly coded before storage in a Dropbox folder. The voices (vowel /a:/) were analyzed by consensus on the same day by two speech-language audiologists who had more than ten years of experience in the voice area using the GRBASI perceptualauditory vocal evaluation scale. Acoustic analysis of the glottic source was performed using the advanced Multi-Dimensional Voice Program software. The resonance focus and the degrees of masculinity and femininity for each voice recording were determined by listening to the CAPE-V phrases. Results: There were significant differences between the groups regarding a greater roughness (discrete degree) (p ¼ 0.031), greater frequency of subjects with F0 between 80e150 Hz (p ¼ 0.003), and a greater frequency of hypernasal resonant focus (p \u003c0.001) in the MPF cases compared with the controls. Conclusion \u0026 recommendations: The MPF group of individuals showed greater roughness (discrete degree), altered vertical resonant focus, more masculine voices, and more severe fundamental frequencies than the controls. This information may contribute to better therapy planning and vocal feminization surgery for transgender women.","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879489,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879489/thumbnails/1.jpg","file_name":"jsm_14_5_supplement_4_e267.pdf","download_url":"https://www.academia.edu/attachments/98879489/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Experience_Report_on_Setting_Up_a_Transd.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879489/jsm_14_5_supplement_4_e267-libre.pdf?1676863995=\u0026response-content-disposition=attachment%3B+filename%3DExperience_Report_on_Setting_Up_a_Transd.pdf\u0026Expires=1733907620\u0026Signature=FAh2PMbm5frxVyU0gUug1lJX7QCkztw9HW6x9v5cjxodJscoebS3ZW67ZttsUkqqfiH1~wiHY4NZ0uT~NCk8Y2fd~biTrXgcg7fNCc16VpHMyFJdLXeIOvmIJsAnGKEqct1wI~LeLXntm1OhguDMfMDRa1dSPvf8sSqv3xGEIHuq2L~sWkVs~xlW9Bu8Vf3IZvdNkEWsP5~RxBLF9HFF2MW6hFT9SkvIDshawpHkxdx4Dp--pFJ2~0SVQJdFN~D9dEH4PJQUu01vSy07XG0KxmJsNS~iITV8McRBESI8R3M~d5JnqsvgXnls~CCP8eLqUCjX8yGpB6yoyAcAC0EoQA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"},{"id":98879490,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879490/thumbnails/1.jpg","file_name":"jsm_14_5_supplement_4_e267.pdf","download_url":"https://www.academia.edu/attachments/98879490/download_file","bulk_download_file_name":"Experience_Report_on_Setting_Up_a_Transd.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879490/jsm_14_5_supplement_4_e267-libre.pdf?1676863992=\u0026response-content-disposition=attachment%3B+filename%3DExperience_Report_on_Setting_Up_a_Transd.pdf\u0026Expires=1733907620\u0026Signature=KhLjmH-78Hpjfgtl01Ae8VMUSy~wIuZBd0NlTlMYJEzPUQqYwCSX2WkOsWbFtY-klOsFBEzQAuMDHVRKRdoyvvwMLhA-YnapT9WWj-HuMLxx~pe0JGqjuhUjTudNxNsWpU58OsKD~~U5ll1Lm5-AD6LvbeUNjQMq2Jk5R7X4X2LUFyPSulqMhaK~h07MSYso-5RuREXCMDvK3nyad9JcvUric5dRfplfjzR3QLCzP36blIgBq~05TwhKK7bIWcRtZyFu29s0RjtmG-QHY4Cl0ynx0H6KALOmSHZ1v3Aae2e5KUJg-Z1WZXzJYmpP0z71dpn9BsMTnP9bUzlhCI5yaQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":26798,"name":"Transgender","url":"https://www.academia.edu/Documents/in/Transgender"},{"id":84236,"name":"Sexual Medicine","url":"https://www.academia.edu/Documents/in/Sexual_Medicine"},{"id":2922956,"name":"Psychology and Cognitive Sciences","url":"https://www.academia.edu/Documents/in/Psychology_and_Cognitive_Sciences"},{"id":3763225,"name":"Medical and Health Sciences","url":"https://www.academia.edu/Documents/in/Medical_and_Health_Sciences"}],"urls":[{"id":29121253,"url":"https://academic.oup.com/jsm/article-pdf/14/Supplement_4b/e267/49152068/jsm_14_5_supplement_4_e267.pdf"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> </div><div class="profile--tab_content_container js-tab-pane tab-pane" data-section-id="17156793" id="papers"><div class="js-work-strip profile--work_container" data-work-id="97188871"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188871/Fortro_F%C3%B3rceps_Para_Trocarte"><img alt="Research paper thumbnail of Fortro - Fórceps Para Trocarte" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188871/Fortro_F%C3%B3rceps_Para_Trocarte">Fortro - Fórceps Para Trocarte</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team when used manually. The exit of the trocar by counter-incision may be distant from the surgical incision, increasing the difficulty of the procedure and the time of surgery. Objective: To create a surgical instrument to fasten and aid the passage of the trocar of drains through the tissues. Methods: Search of precedence described devices to aid the passage of drains and comparison with the design of the new device. Description of the main characteristics and functions of the instrument created to fasten the trocar of the drains, and assist in the passage through the tissues. Results: The search for precedence in the INPI, USPTO and Google Patents databases resulted, in the International patent classification, in two devices for the passage of trocars: a deposit in the INPI and WIPO, and another one in the USPTO, but none designed as forceps. Forceps analysis under study compared the pat...</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188871"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188871"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188871; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188871]").text(description); $(".js-view-count[data-work-id=97188871]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188871; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188871']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188871, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=97188871]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188871,"title":"Fortro - Fórceps Para Trocarte","translated_title":"","metadata":{"abstract":"Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team when used manually. The exit of the trocar by counter-incision may be distant from the surgical incision, increasing the difficulty of the procedure and the time of surgery. Objective: To create a surgical instrument to fasten and aid the passage of the trocar of drains through the tissues. Methods: Search of precedence described devices to aid the passage of drains and comparison with the design of the new device. Description of the main characteristics and functions of the instrument created to fasten the trocar of the drains, and assist in the passage through the tissues. Results: The search for precedence in the INPI, USPTO and Google Patents databases resulted, in the International patent classification, in two devices for the passage of trocars: a deposit in the INPI and WIPO, and another one in the USPTO, but none designed as forceps. Forceps analysis under study compared the pat...","publisher":"Universidade Federal de São Paulo (UNIFESP)","publication_date":{"day":29,"month":6,"year":2017,"errors":{}}},"translated_abstract":"Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team when used manually. The exit of the trocar by counter-incision may be distant from the surgical incision, increasing the difficulty of the procedure and the time of surgery. Objective: To create a surgical instrument to fasten and aid the passage of the trocar of drains through the tissues. Methods: Search of precedence described devices to aid the passage of drains and comparison with the design of the new device. Description of the main characteristics and functions of the instrument created to fasten the trocar of the drains, and assist in the passage through the tissues. Results: The search for precedence in the INPI, USPTO and Google Patents databases resulted, in the International patent classification, in two devices for the passage of trocars: a deposit in the INPI and WIPO, and another one in the USPTO, but none designed as forceps. Forceps analysis under study compared the pat...","internal_url":"https://www.academia.edu/97188871/Fortro_F%C3%B3rceps_Para_Trocarte","translated_internal_url":"","created_at":"2023-02-19T19:12:26.637-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Fortro_Fórceps_Para_Trocarte","translated_slug":"","page_count":null,"language":"en","content_type":"Work","summary":"Introduction: The insertion of surgical drains with trocars can jeopardize the safety of the team when used manually. 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Forceps analysis under study compared the pat...","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[],"research_interests":[{"id":340531,"name":"Sucção","url":"https://www.academia.edu/Documents/in/Succao"},{"id":862505,"name":"Suction","url":"https://www.academia.edu/Documents/in/Suction"},{"id":1286978,"name":"Equipment and Supplies","url":"https://www.academia.edu/Documents/in/Equipment_and_Supplies"},{"id":2257649,"name":"Surgical Instruments","url":"https://www.academia.edu/Documents/in/Surgical_Instruments"},{"id":3553080,"name":"Equipment safety","url":"https://www.academia.edu/Documents/in/Equipment_safety"}],"urls":[{"id":29121258,"url":"http://repositorio.unifesp.br/handle/11600/50153"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188870"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188870/Abordagem_cl%C3%ADnica_e_cir%C3%BArgica_de_pessoas_transg%C3%AAnero_para_estudantes_de_Medicina"><img alt="Research paper thumbnail of Abordagem clínica e cirúrgica de pessoas transgênero: para estudantes de Medicina" class="work-thumbnail" src="https://a.academia-assets.com/images/blank-paper.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188870/Abordagem_cl%C3%ADnica_e_cir%C3%BArgica_de_pessoas_transg%C3%AAnero_para_estudantes_de_Medicina">Abordagem clínica e cirúrgica de pessoas transgênero: para estudantes de Medicina</a></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">A população T é um grupo minoritário formado por pessoas que possuem uma identidade e/ou expressã...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">A população T é um grupo minoritário formado por pessoas que possuem uma identidade e/ou expressão de gênero diferente do sexo atribuído ao nascimento, o que pode causar um desconforto, um mal-estar, chamado “disforia de gênero”. Nesse contexto, é dever do médico estar preparado para um atendimento apropriado, sendo este de caráter primário ou para o encaminhamento às respectivas especialidades, demandando uma noção geral das necessidades que essa população possa ter.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188870"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188870"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188870; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188870]").text(description); $(".js-view-count[data-work-id=97188870]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188870; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188870']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188870, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (false){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "-1" } } $('.js-work-strip[data-work-id=97188870]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188870,"title":"Abordagem clínica e cirúrgica de pessoas transgênero: para estudantes de Medicina","translated_title":"","metadata":{"abstract":"A população T é um grupo minoritário formado por pessoas que possuem uma identidade e/ou expressão de gênero diferente do sexo atribuído ao nascimento, o que pode causar um desconforto, um mal-estar, chamado “disforia de gênero”. Nesse contexto, é dever do médico estar preparado para um atendimento apropriado, sendo este de caráter primário ou para o encaminhamento às respectivas especialidades, demandando uma noção geral das necessidades que essa população possa ter.","publisher":"Editorial Casa"},"translated_abstract":"A população T é um grupo minoritário formado por pessoas que possuem uma identidade e/ou expressão de gênero diferente do sexo atribuído ao nascimento, o que pode causar um desconforto, um mal-estar, chamado “disforia de gênero”. Nesse contexto, é dever do médico estar preparado para um atendimento apropriado, sendo este de caráter primário ou para o encaminhamento às respectivas especialidades, demandando uma noção geral das necessidades que essa população possa ter.","internal_url":"https://www.academia.edu/97188870/Abordagem_cl%C3%ADnica_e_cir%C3%BArgica_de_pessoas_transg%C3%AAnero_para_estudantes_de_Medicina","translated_internal_url":"","created_at":"2023-02-19T19:12:26.539-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[],"slug":"Abordagem_clínica_e_cirúrgica_de_pessoas_transgênero_para_estudantes_de_Medicina","translated_slug":"","page_count":null,"language":"pt","content_type":"Work","summary":"A população T é um grupo minoritário formado por pessoas que possuem uma identidade e/ou expressão de gênero diferente do sexo atribuído ao nascimento, o que pode causar um desconforto, um mal-estar, chamado “disforia de gênero”. Nesse contexto, é dever do médico estar preparado para um atendimento apropriado, sendo este de caráter primário ou para o encaminhamento às respectivas especialidades, demandando uma noção geral das necessidades que essa população possa ter.","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[],"research_interests":[{"id":951,"name":"Humanities","url":"https://www.academia.edu/Documents/in/Humanities"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188869"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188869/Mammoplasty_steps_for_safe_surgery_Evidence_from_literature"><img alt="Research paper thumbnail of Mammoplasty: steps for safe surgery. Evidence from literature" class="work-thumbnail" src="https://attachments.academia-assets.com/98879506/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188869/Mammoplasty_steps_for_safe_surgery_Evidence_from_literature">Mammoplasty: steps for safe surgery. Evidence from literature</a></div><div class="wp-workCard_item"><span>Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery</span><span>, 2021</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Conflitos de interesse: não há. Artigo Especial Mamoplastia redutora: passos para uma cirurgia se...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Conflitos de interesse: não há. Artigo Especial Mamoplastia redutora: passos para uma cirurgia segura 367</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="0ea8c9c3920e79936859b50eef634fcd" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879506,"asset_id":97188869,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879506/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188869"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188869"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188869; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188869]").text(description); $(".js-view-count[data-work-id=97188869]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188869; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188869']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188869, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "0ea8c9c3920e79936859b50eef634fcd" } } $('.js-work-strip[data-work-id=97188869]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188869,"title":"Mammoplasty: steps for safe surgery. Evidence from literature","translated_title":"","metadata":{"publisher":"GN1 Genesis Network","grobid_abstract":"Conflitos de interesse: não há. 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Artigo Especial Mamoplastia redutora: passos para uma cirurgia segura 367","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879506,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879506/thumbnails/1.jpg","file_name":"v36n3a21.pdf","download_url":"https://www.academia.edu/attachments/98879506/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Mammoplasty_steps_for_safe_surgery_Evide.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879506/v36n3a21-libre.pdf?1676863995=\u0026response-content-disposition=attachment%3B+filename%3DMammoplasty_steps_for_safe_surgery_Evide.pdf\u0026Expires=1733907619\u0026Signature=RzUmXf2Gr~fh0dwne-EdIfLc9aKvrlZBmEmzzlBVwMUBYzwd~tWFc1-vsbs-ZbC~WDC-2DpUUVR4ME-WpPSPxfaezyCwnoSBs9poQ-VVGkumtVHvzM28Zdi4keJl~~rEdXWFkhhPWO6NydXyvownXSyreG--yNNYFoiwF4jNHAtbL~vQiSVcqubT23c9jkY4hpK9UI7AM6zBa6Lj7-oPhn2~64WCuasnr8U2FYEV8EsCnRuNDnkF23hILiB9dZ9tdeTGHHLKxiuHw7yQEBHPUZ4HUsvPiflt98IeF5LUn6Tq8Aiy0Hc3Ml18zBC-yZIj5EvVBuXpEWWL9LzmACSzVA__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":1406653,"name":"Mammoplasty","url":"https://www.academia.edu/Documents/in/Mammoplasty"}],"urls":[{"id":29121257,"url":"http://www.rbcp.org.br/detalhe_artigo.asp?id=2997"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188868"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188868/Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants"><img alt="Research paper thumbnail of Influence of postoperative complications on the failure of immediate breast reconstruction with silicone implants" class="work-thumbnail" src="https://attachments.academia-assets.com/98879505/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188868/Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants">Influence of postoperative complications on the failure of immediate breast reconstruction with silicone implants</a></div><div class="wp-workCard_item"><span>Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery</span><span>, 2015</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a si...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a simple method, but can develop complications culminating in implant removal. The aim of this study was to analyze postoperative complications and evaluate their correlation with implant removal. Method: In a period of 4 years, 323 cases of immediate breast reconstruction with silicone implants following total mastectomy were retrospectively studied in the Institut Gustave-Roussy, France. Results: The most frequent complication was lymphocele (34.9%), followed by cutaneous necrosis (22.9%), infection (19.3%), and hematoma (13.3%). Implant removal was more frequent when a surgical complication occurred, and even more frequent when there was more than one type of complication. The most frequent complication leading to implant removal was infection (75.0%). The expander was the implant that had the highest correlation with implant removal. The use of implants with a volume greater than 300 ml was associated with a significantly higher risk of implant removal. Conclusions: 1) The presence of postoperative complications was a risk factor for implant removal. 2) The risk of removal was higher when more than one complication was present. 3) Infection was the main type of complication associated with implant removal. 4) The expander presented a higher risk of complications and implant removal. 5) The use of implants with a volume greater than 300 ml had a greater risk of need for removal.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="36f07bd7933a9c335995a6160a5d58fc" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879505,"asset_id":97188868,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879505/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188868"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188868"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188868; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188868]").text(description); $(".js-view-count[data-work-id=97188868]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188868; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188868']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188868, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "36f07bd7933a9c335995a6160a5d58fc" } } $('.js-work-strip[data-work-id=97188868]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188868,"title":"Influence of postoperative complications on the failure of immediate breast reconstruction with silicone implants","translated_title":"","metadata":{"publisher":"GN1 Genesis Network","ai_title_tag":"Postoperative Complications in Immediate Breast Reconstruction","grobid_abstract":"Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a simple method, but can develop complications culminating in implant removal. The aim of this study was to analyze postoperative complications and evaluate their correlation with implant removal. Method: In a period of 4 years, 323 cases of immediate breast reconstruction with silicone implants following total mastectomy were retrospectively studied in the Institut Gustave-Roussy, France. Results: The most frequent complication was lymphocele (34.9%), followed by cutaneous necrosis (22.9%), infection (19.3%), and hematoma (13.3%). Implant removal was more frequent when a surgical complication occurred, and even more frequent when there was more than one type of complication. The most frequent complication leading to implant removal was infection (75.0%). The expander was the implant that had the highest correlation with implant removal. The use of implants with a volume greater than 300 ml was associated with a significantly higher risk of implant removal. Conclusions: 1) The presence of postoperative complications was a risk factor for implant removal. 2) The risk of removal was higher when more than one complication was present. 3) Infection was the main type of complication associated with implant removal. 4) The expander presented a higher risk of complications and implant removal. 5) The use of implants with a volume greater than 300 ml had a greater risk of need for removal.","publication_date":{"day":null,"month":null,"year":2015,"errors":{}},"publication_name":"Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery","grobid_abstract_attachment_id":98879505},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188868/Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants","translated_internal_url":"","created_at":"2023-02-19T19:12:26.284-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879505,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879505/thumbnails/1.jpg","file_name":"05b81beaa44a083c3c6348b92c1536b59402.pdf","download_url":"https://www.academia.edu/attachments/98879505/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Influence_of_postoperative_complications.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879505/05b81beaa44a083c3c6348b92c1536b59402-libre.pdf?1676863996=\u0026response-content-disposition=attachment%3B+filename%3DInfluence_of_postoperative_complications.pdf\u0026Expires=1733907619\u0026Signature=eS3r2KpIWEk~ZkOkSrX0ebaawy3bVcCIEAe-yJsiXpJVEmgu5lFw3y~a~UN-VnNsuX2KBfps35eoIX4e~Z1hbw9jJLqyDKsUQWMY8J7pZSEOKqKK3cpdfRgvlYq5-M0dg1HHC046Lg8ybhdeZZH~pE9zwbcCAL644HyZLrxdeIBXOcJQudiy9A20B~gRTxNbKFX71r~-6cRdDvnDlpLC0DBOuRyZrzOuOH7szADzi1AX~~IpW2ZhPznM8rPMTRhdZH1g-JJ3DnZEmfrC-bKE2s7oTUN7NnwPAIwnlWNzDDgMSzVMd64r7F8iu0S2YayzLwJ~YLlCeBoEDGHhJIcqyg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Influence_of_postoperative_complications_on_the_failure_of_immediate_breast_reconstruction_with_silicone_implants","translated_slug":"","page_count":8,"language":"en","content_type":"Work","summary":"Introduction: Immediate breast reconstruction with silicone implants following mastectomy is a simple method, but can develop complications culminating in implant removal. The aim of this study was to analyze postoperative complications and evaluate their correlation with implant removal. Method: In a period of 4 years, 323 cases of immediate breast reconstruction with silicone implants following total mastectomy were retrospectively studied in the Institut Gustave-Roussy, France. Results: The most frequent complication was lymphocele (34.9%), followed by cutaneous necrosis (22.9%), infection (19.3%), and hematoma (13.3%). Implant removal was more frequent when a surgical complication occurred, and even more frequent when there was more than one type of complication. The most frequent complication leading to implant removal was infection (75.0%). The expander was the implant that had the highest correlation with implant removal. The use of implants with a volume greater than 300 ml was associated with a significantly higher risk of implant removal. Conclusions: 1) The presence of postoperative complications was a risk factor for implant removal. 2) The risk of removal was higher when more than one complication was present. 3) Infection was the main type of complication associated with implant removal. 4) The expander presented a higher risk of complications and implant removal. 5) The use of implants with a volume greater than 300 ml had a greater risk of need for removal.","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879505,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879505/thumbnails/1.jpg","file_name":"05b81beaa44a083c3c6348b92c1536b59402.pdf","download_url":"https://www.academia.edu/attachments/98879505/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Influence_of_postoperative_complications.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879505/05b81beaa44a083c3c6348b92c1536b59402-libre.pdf?1676863996=\u0026response-content-disposition=attachment%3B+filename%3DInfluence_of_postoperative_complications.pdf\u0026Expires=1733907619\u0026Signature=eS3r2KpIWEk~ZkOkSrX0ebaawy3bVcCIEAe-yJsiXpJVEmgu5lFw3y~a~UN-VnNsuX2KBfps35eoIX4e~Z1hbw9jJLqyDKsUQWMY8J7pZSEOKqKK3cpdfRgvlYq5-M0dg1HHC046Lg8ybhdeZZH~pE9zwbcCAL644HyZLrxdeIBXOcJQudiy9A20B~gRTxNbKFX71r~-6cRdDvnDlpLC0DBOuRyZrzOuOH7szADzi1AX~~IpW2ZhPznM8rPMTRhdZH1g-JJ3DnZEmfrC-bKE2s7oTUN7NnwPAIwnlWNzDDgMSzVMd64r7F8iu0S2YayzLwJ~YLlCeBoEDGHhJIcqyg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":229577,"name":"Silicone","url":"https://www.academia.edu/Documents/in/Silicone"},{"id":1185895,"name":"Breast Reconstruction","url":"https://www.academia.edu/Documents/in/Breast_Reconstruction"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188867"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188867/Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline"><img alt="Research paper thumbnail of Histological modification in TRAM flap in rats treated with pentoxifylline" class="work-thumbnail" src="https://attachments.academia-assets.com/98879510/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188867/Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline">Histological modification in TRAM flap in rats treated with pentoxifylline</a></div><div class="wp-workCard_item"><span>Acta Cirurgica Brasileira</span><span>, 2014</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pent...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS: 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After that, they were submitted to a caudal unipedicle TRAM flap. On the fifth postoperative day, percentages of flap necrosis were determined via the "paper template" method and Tram flap's zone IV skin biopsies were taken for histological analysis. RESULTS: the mean percentage of flap necrosis in group C was 58.7 % and in group P, 31.1 (Wilcoxon test; p = 0.003). Mean capillary vessels number in zone IV's skin in C group was 33.4 and in P group was 71.9 (p=0.008). CONCLUSIONS: Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV).</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="b704ab61423a940d82ee739f5f69f21e" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879510,"asset_id":97188867,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879510/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188867"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188867"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188867; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188867]").text(description); $(".js-view-count[data-work-id=97188867]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188867; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188867']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188867, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "b704ab61423a940d82ee739f5f69f21e" } } $('.js-work-strip[data-work-id=97188867]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188867,"title":"Histological modification in TRAM flap in rats treated with pentoxifylline","translated_title":"","metadata":{"publisher":"FapUNIFESP (SciELO)","grobid_abstract":"To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS: 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After that, they were submitted to a caudal unipedicle TRAM flap. On the fifth postoperative day, percentages of flap necrosis were determined via the \"paper template\" method and Tram flap's zone IV skin biopsies were taken for histological analysis. RESULTS: the mean percentage of flap necrosis in group C was 58.7 % and in group P, 31.1 (Wilcoxon test; p = 0.003). Mean capillary vessels number in zone IV's skin in C group was 33.4 and in P group was 71.9 (p=0.008). CONCLUSIONS: Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV).","publication_date":{"day":null,"month":null,"year":2014,"errors":{}},"publication_name":"Acta Cirurgica Brasileira","grobid_abstract_attachment_id":98879510},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188867/Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline","translated_internal_url":"","created_at":"2023-02-19T19:12:26.179-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879510,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879510/thumbnails/1.jpg","file_name":"0102-8650-acb-29-s2-00034.pdf","download_url":"https://www.academia.edu/attachments/98879510/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Histological_modification_in_TRAM_flap_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879510/0102-8650-acb-29-s2-00034-libre.pdf?1676863998=\u0026response-content-disposition=attachment%3B+filename%3DHistological_modification_in_TRAM_flap_i.pdf\u0026Expires=1733907619\u0026Signature=WJxp~kAAW0XALn~trDypcIG6DywR4Daj~CDPVEkPclGSldrMMWzsVEjxbs9gK0RKcd3DLtcMwBITlHPz5LZrDhUNHJXT8dE0roH~vmVKAMMRWm50-k2tT6PZxwzCtWrRbhN6YjrOGvkLJlXwG9x1LBcbJvTgHuc4rAj5MKTkdOuecEZQElH2AhXp5UF-7eLKy50yNXdrgE0QXEuOXgK1LnDHPNwHwq7NC2fi2QO5K6HVuIG-GiWcYoOzVwJvk8-QmaJjH70G4yZpgmEWpe7F-lcxqt0drASgCxfYfZYDEHycixwm~L~lRWqN8V~xiouAxIugk9Ay2lgAVlRFDenPrQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Histological_modification_in_TRAM_flap_in_rats_treated_with_pentoxifylline","translated_slug":"","page_count":4,"language":"en","content_type":"Work","summary":"To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS: 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After that, they were submitted to a caudal unipedicle TRAM flap. On the fifth postoperative day, percentages of flap necrosis were determined via the \"paper template\" method and Tram flap's zone IV skin biopsies were taken for histological analysis. RESULTS: the mean percentage of flap necrosis in group C was 58.7 % and in group P, 31.1 (Wilcoxon test; p = 0.003). Mean capillary vessels number in zone IV's skin in C group was 33.4 and in P group was 71.9 (p=0.008). CONCLUSIONS: Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV).","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879510,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879510/thumbnails/1.jpg","file_name":"0102-8650-acb-29-s2-00034.pdf","download_url":"https://www.academia.edu/attachments/98879510/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Histological_modification_in_TRAM_flap_i.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879510/0102-8650-acb-29-s2-00034-libre.pdf?1676863998=\u0026response-content-disposition=attachment%3B+filename%3DHistological_modification_in_TRAM_flap_i.pdf\u0026Expires=1733907619\u0026Signature=WJxp~kAAW0XALn~trDypcIG6DywR4Daj~CDPVEkPclGSldrMMWzsVEjxbs9gK0RKcd3DLtcMwBITlHPz5LZrDhUNHJXT8dE0roH~vmVKAMMRWm50-k2tT6PZxwzCtWrRbhN6YjrOGvkLJlXwG9x1LBcbJvTgHuc4rAj5MKTkdOuecEZQElH2AhXp5UF-7eLKy50yNXdrgE0QXEuOXgK1LnDHPNwHwq7NC2fi2QO5K6HVuIG-GiWcYoOzVwJvk8-QmaJjH70G4yZpgmEWpe7F-lcxqt0drASgCxfYfZYDEHycixwm~L~lRWqN8V~xiouAxIugk9Ay2lgAVlRFDenPrQ__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":647,"name":"Surgery","url":"https://www.academia.edu/Documents/in/Surgery"},{"id":26327,"name":"Medicine","url":"https://www.academia.edu/Documents/in/Medicine"},{"id":37826,"name":"Biopsy","url":"https://www.academia.edu/Documents/in/Biopsy"},{"id":71421,"name":"Capillaries","url":"https://www.academia.edu/Documents/in/Capillaries"},{"id":162553,"name":"Skin","url":"https://www.academia.edu/Documents/in/Skin"},{"id":235677,"name":"Behavioral Animal Models","url":"https://www.academia.edu/Documents/in/Behavioral_Animal_Models"},{"id":244814,"name":"Clinical Sciences","url":"https://www.academia.edu/Documents/in/Clinical_Sciences"},{"id":375054,"name":"Rats","url":"https://www.academia.edu/Documents/in/Rats"},{"id":439784,"name":"Saline","url":"https://www.academia.edu/Documents/in/Saline"},{"id":448603,"name":"Necrosis","url":"https://www.academia.edu/Documents/in/Necrosis"},{"id":549280,"name":"Reproducibility of Results","url":"https://www.academia.edu/Documents/in/Reproducibility_of_Results"},{"id":564879,"name":"Wistar Rats","url":"https://www.academia.edu/Documents/in/Wistar_Rats"},{"id":1996229,"name":"Pentoxifylline","url":"https://www.academia.edu/Documents/in/Pentoxifylline"},{"id":2463495,"name":"Random Allocation","url":"https://www.academia.edu/Documents/in/Random_Allocation"},{"id":3103472,"name":"Rectus Abdominis","url":"https://www.academia.edu/Documents/in/Rectus_Abdominis"},{"id":3696980,"name":"Platelet Aggregation Inhibitors","url":"https://www.academia.edu/Documents/in/Platelet_Aggregation_Inhibitors"},{"id":3724721,"name":"Surgical Flaps","url":"https://www.academia.edu/Documents/in/Surgical_Flaps"}],"urls":[]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188866"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188866/Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes"><img alt="Research paper thumbnail of Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes" class="work-thumbnail" src="https://attachments.academia-assets.com/98879520/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188866/Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes">Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes</a></div><div class="wp-workCard_item"><span>Neuroscience Letters</span><span>, 2006</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">In this study, we investigated agents that increased intracellular calcium levels and their corre...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">In this study, we investigated agents that increased intracellular calcium levels and their correlation with apoptotic cell death induction. We used rat astrocytes to investigate the increase in cytosolic Ca 2+ (Ca c 2+) and apoptosis induction by drugs that mobilize Ca 2+ from different sources. We observed that thapsigargin (Thap), caffeine (Caff) and FCCP which caused similar increases in Ca c 2+ levels (30-40%), also induced similar apoptotic rates (30-35%). On the other hand, antimycin (Anti), staurosporine (STS) and ethanol (Eth) promoted higher increases in Ca c 2+ (55-65 %) and higher apoptotic rates (55-85%). Eth induced cell death in a concentration-and time-dependent manner. After treatment with Eth plus Caff for 6, 12 and 24 h, these effects were strongly potentiated. Results suggest that there might be a correlation between Ca c 2+ increase and the rate of apoptosis. It is possible that Eth induces cell death by activation of more than one pathway and Ca 2+ might be one of the elements involved. The present work indicates that Ca 2+ can potentiate death by ethanol in rat astrocytes.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="7e9e2fe009dc848e407d210f4d5089c6" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879520,"asset_id":97188866,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879520/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188866"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188866"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188866; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188866]").text(description); $(".js-view-count[data-work-id=97188866]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188866; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188866']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188866, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "7e9e2fe009dc848e407d210f4d5089c6" } } $('.js-work-strip[data-work-id=97188866]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188866,"title":"Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes","translated_title":"","metadata":{"publisher":"Elsevier BV","grobid_abstract":"In this study, we investigated agents that increased intracellular calcium levels and their correlation with apoptotic cell death induction. We used rat astrocytes to investigate the increase in cytosolic Ca 2+ (Ca c 2+) and apoptosis induction by drugs that mobilize Ca 2+ from different sources. We observed that thapsigargin (Thap), caffeine (Caff) and FCCP which caused similar increases in Ca c 2+ levels (30-40%), also induced similar apoptotic rates (30-35%). On the other hand, antimycin (Anti), staurosporine (STS) and ethanol (Eth) promoted higher increases in Ca c 2+ (55-65 %) and higher apoptotic rates (55-85%). Eth induced cell death in a concentration-and time-dependent manner. After treatment with Eth plus Caff for 6, 12 and 24 h, these effects were strongly potentiated. Results suggest that there might be a correlation between Ca c 2+ increase and the rate of apoptosis. It is possible that Eth induces cell death by activation of more than one pathway and Ca 2+ might be one of the elements involved. The present work indicates that Ca 2+ can potentiate death by ethanol in rat astrocytes.","publication_date":{"day":null,"month":null,"year":2006,"errors":{}},"publication_name":"Neuroscience Letters","grobid_abstract_attachment_id":98879520},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188866/Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes","translated_internal_url":"","created_at":"2023-02-19T19:12:26.018-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879520,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879520/thumbnails/1.jpg","file_name":"j.neulet.2005.09.06620230220-1-1alncbk.pdf","download_url":"https://www.academia.edu/attachments/98879520/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptotic_effect_of_ethanol_is_potentiat.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879520/j.neulet.2005.09.06620230220-1-1alncbk-libre.pdf?1676863988=\u0026response-content-disposition=attachment%3B+filename%3DApoptotic_effect_of_ethanol_is_potentiat.pdf\u0026Expires=1733907619\u0026Signature=AZjdoKez0RqjQf0EOWp3g6lqb2W4gkJQmTJbwzAAb~xWfyc51F6lR4f8kd9WcowhzyXZuZjyPEJQ1XotEBLGNgOGE0lFDv71Vks3PwJK6RsTFIE-lXyYcL2OV6fPO~PgyD4yBPK0sh6mUsirnxH-mt0Jw4n8NzFbJcUy78PUPeYR3S5h9K7Rl7IHf8h54M1Jj3Og9dkU1DCy1dQ9nn71lEVUCqVG-ECu5fC3DXpf1TYN9InRL3bvwBY9eT9KDnIipObXkjBKjHEKZ7Q4mBNG0NN6rfViQtDt2tgsNkeS4hGWugrcHGy5gaPx-q5RuJNKs7D3sxgEqkPmu5Lk4Csf0w__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Apoptotic_effect_of_ethanol_is_potentiated_by_caffeine_induced_calcium_release_in_rat_astrocytes","translated_slug":"","page_count":5,"language":"en","content_type":"Work","summary":"In this study, we investigated agents that increased intracellular calcium levels and their correlation with apoptotic cell death induction. We used rat astrocytes to investigate the increase in cytosolic Ca 2+ (Ca c 2+) and apoptosis induction by drugs that mobilize Ca 2+ from different sources. We observed that thapsigargin (Thap), caffeine (Caff) and FCCP which caused similar increases in Ca c 2+ levels (30-40%), also induced similar apoptotic rates (30-35%). On the other hand, antimycin (Anti), staurosporine (STS) and ethanol (Eth) promoted higher increases in Ca c 2+ (55-65 %) and higher apoptotic rates (55-85%). Eth induced cell death in a concentration-and time-dependent manner. After treatment with Eth plus Caff for 6, 12 and 24 h, these effects were strongly potentiated. Results suggest that there might be a correlation between Ca c 2+ increase and the rate of apoptosis. It is possible that Eth induces cell death by activation of more than one pathway and Ca 2+ might be one of the elements involved. The present work indicates that Ca 2+ can potentiate death by ethanol in rat astrocytes.","owner":{"id":98888080,"first_name":"Dr. Adriano","middle_initials":null,"last_name":"Brasolin","page_name":"DrAdrianoBrasolin","domain_name":"unifesp","created_at":"2018-12-09T18:55:52.911-08:00","display_name":"Dr. Adriano Brasolin","url":"https://unifesp.academia.edu/DrAdrianoBrasolin"},"attachments":[{"id":98879520,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879520/thumbnails/1.jpg","file_name":"j.neulet.2005.09.06620230220-1-1alncbk.pdf","download_url":"https://www.academia.edu/attachments/98879520/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAxOSw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Apoptotic_effect_of_ethanol_is_potentiat.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879520/j.neulet.2005.09.06620230220-1-1alncbk-libre.pdf?1676863988=\u0026response-content-disposition=attachment%3B+filename%3DApoptotic_effect_of_ethanol_is_potentiat.pdf\u0026Expires=1733907619\u0026Signature=AZjdoKez0RqjQf0EOWp3g6lqb2W4gkJQmTJbwzAAb~xWfyc51F6lR4f8kd9WcowhzyXZuZjyPEJQ1XotEBLGNgOGE0lFDv71Vks3PwJK6RsTFIE-lXyYcL2OV6fPO~PgyD4yBPK0sh6mUsirnxH-mt0Jw4n8NzFbJcUy78PUPeYR3S5h9K7Rl7IHf8h54M1Jj3Og9dkU1DCy1dQ9nn71lEVUCqVG-ECu5fC3DXpf1TYN9InRL3bvwBY9eT9KDnIipObXkjBKjHEKZ7Q4mBNG0NN6rfViQtDt2tgsNkeS4hGWugrcHGy5gaPx-q5RuJNKs7D3sxgEqkPmu5Lk4Csf0w__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"research_interests":[{"id":237,"name":"Cognitive Science","url":"https://www.academia.edu/Documents/in/Cognitive_Science"},{"id":6599,"name":"Flow Cytometry","url":"https://www.academia.edu/Documents/in/Flow_Cytometry"},{"id":7710,"name":"Biology","url":"https://www.academia.edu/Documents/in/Biology"},{"id":9534,"name":"Calcium","url":"https://www.academia.edu/Documents/in/Calcium"},{"id":12981,"name":"Enzyme Inhibitors","url":"https://www.academia.edu/Documents/in/Enzyme_Inhibitors"},{"id":24731,"name":"Apoptosis","url":"https://www.academia.edu/Documents/in/Apoptosis"},{"id":67129,"name":"Caffeine","url":"https://www.academia.edu/Documents/in/Caffeine"},{"id":112576,"name":"Cell Death","url":"https://www.academia.edu/Documents/in/Cell_Death"},{"id":121705,"name":"Ethanol","url":"https://www.academia.edu/Documents/in/Ethanol"},{"id":122187,"name":"Endoplasmic Reticulum","url":"https://www.academia.edu/Documents/in/Endoplasmic_Reticulum"},{"id":130116,"name":"Astrocyte","url":"https://www.academia.edu/Documents/in/Astrocyte"},{"id":196442,"name":"Astrocytes","url":"https://www.academia.edu/Documents/in/Astrocytes"},{"id":891369,"name":"Manganese Compounds","url":"https://www.academia.edu/Documents/in/Manganese_Compounds"},{"id":1599862,"name":"Fura","url":"https://www.academia.edu/Documents/in/Fura"},{"id":1823382,"name":"Intracellular Calcium","url":"https://www.academia.edu/Documents/in/Intracellular_Calcium"},{"id":2260515,"name":"Chlorides","url":"https://www.academia.edu/Documents/in/Chlorides"},{"id":3428040,"name":"Central nervous system stimulants","url":"https://www.academia.edu/Documents/in/Central_nervous_system_stimulants"},{"id":3545627,"name":"Drug synergism","url":"https://www.academia.edu/Documents/in/Drug_synergism"},{"id":3950591,"name":"Antimycin A","url":"https://www.academia.edu/Documents/in/Antimycin_A"}],"urls":[{"id":29121256,"url":"https://api.elsevier.com/content/article/PII:S0304394005011109?httpAccept=text/xml"}]}, dispatcherData: dispatcherData }); $(this).data('initialized', true); } }); $a.trackClickSource(".js-work-strip-work-link", "profile_work_strip") }); </script> <div class="js-work-strip profile--work_container" data-work-id="97188862"><div class="profile--work_thumbnail hidden-xs"><a class="js-work-strip-work-link" data-click-track="profile-work-strip-thumbnail" href="https://www.academia.edu/97188862/Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health"><img alt="Research paper thumbnail of Experience Report on Setting Up a Transdisciplinary Outpatient Unit for Transgender Health" class="work-thumbnail" src="https://attachments.academia-assets.com/98879489/thumbnails/1.jpg" /></a></div><div class="wp-workCard wp-workCard_itemContainer"><div class="wp-workCard_item wp-workCard--title"><a class="js-work-strip-work-link text-gray-darker" data-click-track="profile-work-strip-title" href="https://www.academia.edu/97188862/Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health">Experience Report on Setting Up a Transdisciplinary Outpatient Unit for Transgender Health</a></div><div class="wp-workCard_item"><span>The Journal of Sexual Medicine</span><span>, 2017</span></div><div class="wp-workCard_item"><span class="js-work-more-abstract-truncated">Introduction & objectives: Voice is an important gender marker in the transition process as a tra...</span><a class="js-work-more-abstract" data-broccoli-component="work_strip.more_abstract" data-click-track="profile-work-strip-more-abstract" href="javascript:;"><span> more </span><span><i class="fa fa-caret-down"></i></span></a><span class="js-work-more-abstract-untruncated hidden">Introduction & objectives: Voice is an important gender marker in the transition process as a transgender individual accepts a new gender identity. Perceptive-auditory and acoustic analyses of the voices of these individuals have determined that vocal pitch is one of the most important markers of gender. The aim of this study was to describe and relate aspects of a perceptual-auditory analysis and the fundamental frequency of male-to-female (MPF) transsexual individuals. Population sample: A case-control study was carried out with individuals aged 19 to 52 years who attended the Gender Identity Program of the Hospital de Clínicas of Porto Alegre. Methods: Vocal recordings from the MPF transgender individuals (vowel / a: / and six phrases of Consensus Auditory Perceptual Evaluation Voice (CAPE-V)) were edited and randomly coded before storage in a Dropbox folder. The voices (vowel /a:/) were analyzed by consensus on the same day by two speech-language audiologists who had more than ten years of experience in the voice area using the GRBASI perceptualauditory vocal evaluation scale. Acoustic analysis of the glottic source was performed using the advanced Multi-Dimensional Voice Program software. The resonance focus and the degrees of masculinity and femininity for each voice recording were determined by listening to the CAPE-V phrases. Results: There were significant differences between the groups regarding a greater roughness (discrete degree) (p ¼ 0.031), greater frequency of subjects with F0 between 80e150 Hz (p ¼ 0.003), and a greater frequency of hypernasal resonant focus (p <0.001) in the MPF cases compared with the controls. Conclusion & recommendations: The MPF group of individuals showed greater roughness (discrete degree), altered vertical resonant focus, more masculine voices, and more severe fundamental frequencies than the controls. This information may contribute to better therapy planning and vocal feminization surgery for transgender women.</span></div><div class="wp-workCard_item wp-workCard--actions"><span class="work-strip-bookmark-button-container"></span><a id="e41ac712fb3bc5a9925d104c16c044a8" class="wp-workCard--action" rel="nofollow" data-click-track="profile-work-strip-download" data-download="{"attachment_id":98879489,"asset_id":97188862,"asset_type":"Work","button_location":"profile"}" href="https://www.academia.edu/attachments/98879489/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&s=profile"><span><i class="fa fa-arrow-down"></i></span><span>Download</span></a><span class="wp-workCard--action visible-if-viewed-by-owner inline-block" style="display: none;"><span class="js-profile-work-strip-edit-button-wrapper profile-work-strip-edit-button-wrapper" data-work-id="97188862"><a class="js-profile-work-strip-edit-button" tabindex="0"><span><i class="fa fa-pencil"></i></span><span>Edit</span></a></span></span><span id="work-strip-rankings-button-container"></span></div><div class="wp-workCard_item wp-workCard--stats"><span><span><span class="js-view-count view-count u-mr2x" data-work-id="97188862"><i class="fa fa-spinner fa-spin"></i></span><script>$(function () { var workId = 97188862; window.Academia.workViewCountsFetcher.queue(workId, function (count) { var description = window.$h.commaizeInt(count) + " " + window.$h.pluralize(count, 'View'); $(".js-view-count[data-work-id=97188862]").text(description); $(".js-view-count[data-work-id=97188862]").attr('title', description).tooltip(); }); });</script></span></span><span><span class="percentile-widget hidden"><span class="u-mr2x work-percentile"></span></span><script>$(function () { var workId = 97188862; window.Academia.workPercentilesFetcher.queue(workId, function (percentileText) { var container = $(".js-work-strip[data-work-id='97188862']"); container.find('.work-percentile').text(percentileText.charAt(0).toUpperCase() + percentileText.slice(1)); container.find('.percentile-widget').show(); container.find('.percentile-widget').removeClass('hidden'); }); });</script></span><span><script>$(function() { new Works.PaperRankView({ workId: 97188862, container: "", }); });</script></span></div><div id="work-strip-premium-row-container"></div></div></div><script> require.config({ waitSeconds: 90 })(["https://a.academia-assets.com/assets/wow_profile-f77ea15d77ce96025a6048a514272ad8becbad23c641fc2b3bd6e24ca6ff1932.js","https://a.academia-assets.com/assets/work_edit-ad038b8c047c1a8d4fa01b402d530ff93c45fee2137a149a4a5398bc8ad67560.js"], function() { // from javascript_helper.rb var dispatcherData = {} if (true){ window.WowProfile.dispatcher = window.WowProfile.dispatcher || _.clone(Backbone.Events); dispatcherData = { dispatcher: window.WowProfile.dispatcher, downloadLinkId: "e41ac712fb3bc5a9925d104c16c044a8" } } $('.js-work-strip[data-work-id=97188862]').each(function() { if (!$(this).data('initialized')) { new WowProfile.WorkStripView({ el: this, workJSON: {"id":97188862,"title":"Experience Report on Setting Up a Transdisciplinary Outpatient Unit for Transgender Health","translated_title":"","metadata":{"publisher":"Oxford University Press (OUP)","grobid_abstract":"Introduction \u0026 objectives: Voice is an important gender marker in the transition process as a transgender individual accepts a new gender identity. Perceptive-auditory and acoustic analyses of the voices of these individuals have determined that vocal pitch is one of the most important markers of gender. The aim of this study was to describe and relate aspects of a perceptual-auditory analysis and the fundamental frequency of male-to-female (MPF) transsexual individuals. Population sample: A case-control study was carried out with individuals aged 19 to 52 years who attended the Gender Identity Program of the Hospital de Clínicas of Porto Alegre. Methods: Vocal recordings from the MPF transgender individuals (vowel / a: / and six phrases of Consensus Auditory Perceptual Evaluation Voice (CAPE-V)) were edited and randomly coded before storage in a Dropbox folder. The voices (vowel /a:/) were analyzed by consensus on the same day by two speech-language audiologists who had more than ten years of experience in the voice area using the GRBASI perceptualauditory vocal evaluation scale. Acoustic analysis of the glottic source was performed using the advanced Multi-Dimensional Voice Program software. The resonance focus and the degrees of masculinity and femininity for each voice recording were determined by listening to the CAPE-V phrases. Results: There were significant differences between the groups regarding a greater roughness (discrete degree) (p ¼ 0.031), greater frequency of subjects with F0 between 80e150 Hz (p ¼ 0.003), and a greater frequency of hypernasal resonant focus (p \u003c0.001) in the MPF cases compared with the controls. Conclusion \u0026 recommendations: The MPF group of individuals showed greater roughness (discrete degree), altered vertical resonant focus, more masculine voices, and more severe fundamental frequencies than the controls. This information may contribute to better therapy planning and vocal feminization surgery for transgender women.","publication_date":{"day":null,"month":null,"year":2017,"errors":{}},"publication_name":"The Journal of Sexual Medicine","grobid_abstract_attachment_id":98879489},"translated_abstract":null,"internal_url":"https://www.academia.edu/97188862/Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health","translated_internal_url":"","created_at":"2023-02-19T19:11:55.947-08:00","preview_url":null,"current_user_can_edit":null,"current_user_is_owner":null,"owner_id":98888080,"coauthors_can_edit":true,"document_type":"paper","co_author_tags":[],"downloadable_attachments":[{"id":98879489,"title":"","file_type":"pdf","scribd_thumbnail_url":"https://attachments.academia-assets.com/98879489/thumbnails/1.jpg","file_name":"jsm_14_5_supplement_4_e267.pdf","download_url":"https://www.academia.edu/attachments/98879489/download_file?st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&st=MTczMzkwNDAyMCw4LjIyMi4yMDguMTQ2&","bulk_download_file_name":"Experience_Report_on_Setting_Up_a_Transd.pdf","bulk_download_url":"https://d1wqtxts1xzle7.cloudfront.net/98879489/jsm_14_5_supplement_4_e267-libre.pdf?1676863995=\u0026response-content-disposition=attachment%3B+filename%3DExperience_Report_on_Setting_Up_a_Transd.pdf\u0026Expires=1733907619\u0026Signature=HuMJKLLmY3cAvxZ9zmaeGQKcqmJAgsLdMog-KHSQ5HnWK~wxnhmkmkHSU58lNX~xH1Z7aL8Fd18GVXperAVqpHZXRJoWmZ0FwfBgsgyxMcL5xrs8xXBivTnR5ixlsgFleXZATeCnB08YitofxRfNeA0HIzGGnQ2hoYWsGaTbRMgROO4~00RtrQYJ~dV92FxQFU2fYmIYZxdZ0Ra2kCW4-gAsNStXTMvLJxJXnP7gz9p3n4LCJfXsDnlsCk91fosqoJcnmfLIrIdfDaChCz~LTxEuZgXrUw-fsNzVRNSPi-enfqcD9zAGjshOb-UhiCNgAF2m~o4LloEA0hMlPgBYHg__\u0026Key-Pair-Id=APKAJLOHF5GGSLRBV4ZA"}],"slug":"Experience_Report_on_Setting_Up_a_Transdisciplinary_Outpatient_Unit_for_Transgender_Health","translated_slug":"","page_count":1,"language":"en","content_type":"Work","summary":"Introduction \u0026 objectives: Voice is an important gender marker in the transition process as a transgender individual accepts a new gender identity. Perceptive-auditory and acoustic analyses of the voices of these individuals have determined that vocal pitch is one of the most important markers of gender. The aim of this study was to describe and relate aspects of a perceptual-auditory analysis and the fundamental frequency of male-to-female (MPF) transsexual individuals. Population sample: A case-control study was carried out with individuals aged 19 to 52 years who attended the Gender Identity Program of the Hospital de Clínicas of Porto Alegre. Methods: Vocal recordings from the MPF transgender individuals (vowel / a: / and six phrases of Consensus Auditory Perceptual Evaluation Voice (CAPE-V)) were edited and randomly coded before storage in a Dropbox folder. The voices (vowel /a:/) were analyzed by consensus on the same day by two speech-language audiologists who had more than ten years of experience in the voice area using the GRBASI perceptualauditory vocal evaluation scale. Acoustic analysis of the glottic source was performed using the advanced Multi-Dimensional Voice Program software. The resonance focus and the degrees of masculinity and femininity for each voice recording were determined by listening to the CAPE-V phrases. Results: There were significant differences between the groups regarding a greater roughness (discrete degree) (p ¼ 0.031), greater frequency of subjects with F0 between 80e150 Hz (p ¼ 0.003), and a greater frequency of hypernasal resonant focus (p \u003c0.001) in the MPF cases compared with the controls. Conclusion \u0026 recommendations: The MPF group of individuals showed greater roughness (discrete degree), altered vertical resonant focus, more masculine voices, and more severe fundamental frequencies than the controls. 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