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Mouse Models of Human Cancer Database (MMHCdb)
<!doctype html> <html> <head> <meta charset="UTF-8"> <meta http-equiv="X-UA-Compatible" content="IE=edge,chrome=1"> <meta name="keywords" content="mtb, mmhc, mouse, tumor, biology, jax, lab, laboratory, jackson, mgi, genome, informatics"> <meta name="description" content="MMHCdb has been designed to aid researchers in such areas as choosing experimental models, reviewing patterns of mutations in specific cancers, and identifying genes that are commonly mutated across a spectrum of cancers."> <title>Mouse Models of Human Cancer Database (MMHCdb)</title> <link rel="stylesheet" type="text/css" href="//maxcdn.bootstrapcdn.com/font-awesome/4.7.0/css/font-awesome.min.css"> <link rel="stylesheet" type="text/css" href="/_res/css/fonts.css"/> <link rel="stylesheet" type="text/css" href="/_res/css/tool-base.css"/> <script src="https://code.jquery.com/jquery-3.6.3.min.js" integrity="sha256-pvPw+upLPUjgMXY0G+8O0xUf+/Im1MZjXxxgOcBQBXU=" crossorigin="anonymous"></script> <!--<script 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class="dropdown"><span>Searches/Tools</span> <ul> <li><a href="/mtbwi/dynamicGrid.do">Tumor Frequency Grid (inbred strains)</a></li> <li><a href="/mtbwi/pdxSearch.do">Patient Derived Xenograft (PDX) Search</a></li> <li><a href="/mtbwi/pdxLikeMe.do">PDX Like Me</a></li> <li><a class="link-external" href="http://www.cancermodels.org" target="_new">CancerModels.org</a></li> </ul> </li> <li class="dropdown"><span>About</span> <ul> <li><a href="/mtbwi/about-us.jsp">About Us</a></li> <li><a href="/mtbwi/publications.jsp">Publications</a></li> <li><a href="/mtbwi/help.jsp">Help</a></li> <li><a href="/mtbwi/news-events.jsp">News & Events</a></li> </ul> </li> </ul></nav> </header> <main> <header class="container"> <h1>Mouse Models of Human Cancer Database (MMHCdb)</h1> <div id="subnav"> </div></header> <section class="container" id="mmhc-summary"> <p>MMHCdb is a comprehensive, expertly curated resource of diverse mouse models of human cancer.</p> <p>We focus on:</p> <ul><li>spontaneous and induced tumors in mice</li><li>genetically defined mouse models of cancer (inbred, hybrid, mutant, and genetically engineered strains of mice)</li><li>Patient Derived Xenograft (PDX) models</li></ul> </section> <section class="container" id="mmhc-detail"> <div id="model-counts" style="overflow:visible"> <table> <caption> <h2>Top Mouse Models of Human Cancer</h2> </caption> <thead> <tr> <th></th> <th colspan="2"><a href="https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2024/2024-cancer-facts-and-figures-acs.pdf" target="_blank">American Cancer Society Facts & Figures 2024</a></th> <th colspan="4" data-tip="Human Models exclude tumors classified as : Atypia, Cyst, Dysplasia, Foci, Hyperplasia, Lesion, Metaplasia, Preneoplastic lesion, Squamous cell hyperplasia, Nevus and Transitional cell hyperplasia">Mouse Models</th> </tr> <tr> <th>Cancer Site</th> <th data-tip="Data: American Cancer Society Facts & Figures">Mortality Rank</th> <th data-tip="Data: American Cancer Society Facts & Figures">Estimated deaths USA</th> <th data-tip="Mutant strains: targeted, transgenic, gene trapped, chemically induced, radiation induced, etc.">Mutant Strains</th> <th data-tip="Non mutant strains: inbred, hybrid, outbred, fostered, chimeric, etc.">Other Strains</th> <th>All Strains</th> <th data-tip="PDX Models: Patient derived xenograft">PDX Models</th> </tr> </thead> <tbody><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Lung, Bronchus, Larynx, Paranasal sinus, Trachea">Lung & other respiratory</td> <td>[1]</td> <td>130,450</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Lung"">59</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Lung"">116</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Lung"">175</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Lung&">79</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Intestine, Small Intestine, Large Intestine, Duodenum, Jejunum, Ileum, Ileocecal Junction, Cecum, Colon, Rectum, Anus">Colon & other intestine</td> <td>[2]</td> <td>57,290</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Colon+and+other+intestine"">116</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Colon+and+other+intestine"">4</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Colon+and+other+intestine"">120</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Anal&primarySites=Appendix&primarySites=Cecum&primarySites=Colon&primarySites=Duodenum&primarySites=Rectum&primarySites=Ampulla+of+Vater&">81</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Leukemia, Lymphoma, Myeloma, Leukocyte, Blood, Bone marrow, Dendritic cell, Erythroblast, Erythrocyte, Hematopoietic stem cell, Lymph node, Lymphatic vessel, Lymphoid tissue, Peyer's patch, Reticular cell, Reticulocyte, Spleen, Thymus">Lymphohematopoietic</td> <td>[3]</td> <td>57,260</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Lymphohematopoietic"">142</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Lymphohematopoietic"">43</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Lymphohematopoietic"">185</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Blood&primarySites=Bone+marrow&primarySites=Lymph+node&">30</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Pancreas">Pancreas</td> <td>[4]</td> <td>51,750</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Pancreas"">38</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Pancreas"">2</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Pancreas"">40</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Pancreas&">15</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Mammary gland">Breast</td> <td>[5]</td> <td>42,780</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Breast"">183</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Breast"">33</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Breast"">216</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Breast&">46</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Prostate gland">Prostate</td> <td>[6]</td> <td>35,250</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Prostate"">55</a></td> <td>0</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Prostate"">55</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Prostate+gland&">2</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Liver, Bile duct">Liver & bile duct</td> <td>[7]</td> <td>29,840</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Liver+and+bile+duct"">25</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Liver+and+bile+duct"">24</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Liver+and+bile+duct"">49</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Liver&primarySites=Bile+duct&">2</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Brain, Meninges, Spinal cord, Nerve, Neuroblast, Neuroectoderm, Ganglion, Nerve sheath, Schwann cell">Brain & other nervous system</td> <td>[8]</td> <td>18,760</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Brain+and+other+nervous+system"">42</a></td> <td>0</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Brain+and+other+nervous+system"">42</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Brain&">25</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Uterus, Cervix">Uterus & cervix</td> <td>[9]</td> <td>17,610</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Uterus+and+cervix"">7</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Uterus+and+cervix"">3</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Uterus+and+cervix"">10</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Uterus&primarySites=Endometrium&">6</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Urinary bladder">Urinary bladder</td> <td>[10]</td> <td>16,840</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Urinary+bladder"">7</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Urinary+bladder"">1</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Urinary+bladder"">8</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Bladder&">27</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Esophagus">Esophagus</td> <td>[11]</td> <td>16,130</td> <td>0</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Esophagus"">8</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Esophagus"">8</a></td> <td>0</td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Kidney, Renal pelvis">Kidney & renal pelvis</td> <td>[12]</td> <td>14,390</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Kidney+and+renal+pelvis"">5</a></td> <td>0</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Kidney+and+renal+pelvis"">5</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Kidney&">8</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Skin, Skin gland">Skin</td> <td>[13]</td> <td>13,120</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Skin"">26</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Skin"">13</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Skin"">39</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Skin&">20</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Ovary">Ovary</td> <td>[14]</td> <td>12,740</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Ovary"">9</a></td> <td>0</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Ovary"">9</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Ovary&">12</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Oral cavity, Pharynx, Gingiva, Mouth, Salivary gland, Tongue, Tooth">Oral cavity & pharynx</td> <td>[15]</td> <td>12,230</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Oral+cavity"">3</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Oral+cavity"">3</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Oral+cavity"">6</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Salivary+gland&primarySites=Tonsil&">3</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Stomach, Forestomach (mouse-specific)">Stomach</td> <td>[16]</td> <td>10,880</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Stomach"">17</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Stomach"">7</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Stomach"">24</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Stomach&">1</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Abdominal cavity, Abdominal wall, Adipose tissue, Connective tissue, Mediastinum, Mesodermal cell/mesoblast, Mesothelium, Muscle, Myoepithelial cell, Notochord, Pericardium, Pericyte, Periosteum, Perirenal tissue, Peritoneal cavity, Peritoneum, Pleura, Pleural cavity, Retroperitoneum, Thoracic cavity, Blood vessel, Heart">Soft tissue including heart</td> <td>[17]</td> <td>5,200</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Soft+tissue+including+heart"">27</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Soft+tissue+including+heart"">20</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Soft+tissue+including+heart"">47</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Soft+tissue&primarySites=Pleural+cavity&">28</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Gallbladder">Gallbladder & other biliary</td> <td>[18]</td> <td>4,530</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Gallbladder"">2</a></td> <td>0</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Gallbladder"">2</a></td> <td>0</td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Adrenal gland, Parathyroid gland, Pineal gland, Pituitary gland, Thyroid gland">Endocrine system</td> <td>[19]</td> <td>3,300</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Endocrine+system"">66</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:false&fq=humanTissue%3A"Endocrine+system"">2</a></td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Endocrine+system"">68</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Adrenal+gland&">1</a></td> </tr><tr> <td data-tip="Corresponding mouse tissues in MMHCdb: Bone, Cartilage, Ligament, Synovium, Tendon">Bones & joints</td> <td>[20]</td> <td>2,050</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=mutant:true&fq=humanTissue%3A"Bone+and+joint"">5</a></td> <td>0</td> <td><a target="_blank" href="/mtbwi/facetedSearch.do#fq=minFC:1&fq=humanTissue%3A"Bone+and+joint"">5</a></td> <td><a target="_blank" href="/mtbwi/pdxSearchResults.do?primarySites=Bone&">11</a></td> </tr></tbody></table> </div> <div id="updates" class="col-md-3 col-xs-12"> <h2>News & Events</h2> <ul> <li>MMHCdb has launched a <a href="https://www.youtube.com/@MMHCdb" target="_blank">YouTube</a> page with tutorial videos covering multiple aspects of the database. Tutorials for the Advanced Search Page, the Tumor Frequency Grid and the Patient Derived Xenograft Search Page as well as a general overview of the entire database have been posted. More videos will be posted periodically.</li> <li>Read our latest publication about MMHCdb: <a href="https://journals.biologists.com/dmm/article-lookup/doi/10.1242/dmm.050001" target="_blank">Begley DA, Disease Models & Mechanisms, 2023 Mar 27.</a> </li> <li>Stop by our <a href="/mtbwi/live/www/html/AACRPoster_MMHCDB_2023_FINAL.pdf" target="_blank">poster</a> at the AACR annual meeting 2023, 14-19 April, Orlando on Sunday April 16<sup>th</sup>.</li> <li>PDXFinder has become <a target="_blank" href="https://www.cancermodels.org">PDCMFinder.</a> It now includes organoids and cell lines and has a new URL <a target="_blank" href="https://www.cancermodels.org">www.cancermodels.org</a></li> <li>New mini-grids have been added to MMHCdb on select Reference Summary pages for studies that emphasize the differences in tumor frequencies observed in mice with the same genotype on a variety of genetic backgrounds. <a href="/mtbwi/referenceDetails.do?accId=33376133">Example.</a> (November 2022)</li> <li>MMHCdb now contains over 110,000 tumor frequency records! (April 2022)</li> <li>MMHCdb will present a poster at the AACR annual meeting, April 8-13, 2022, New Orleans.</li> <li>MMHCdb is featured as the primary repository for data from The Jackson Laboratory's lung cancer PDX resource published in bioRxiv (Woo, X.Y., et al.) <a href="https://www.biorxiv.org/content/10.1101/2022.03.06.483171v1" target="_blank">A Genomically and Clinically Annotated Patient Derived Xenograft (PDX) Resource for Preclinical Research in Non-Small Cell Lung Cancer</a>. Data about the models in this resource are also accessible from PDX Finder. (March 2022)</li> <li>MMHCdb is highlighted in Chapter 2 of Pathology of genetically engineered mice and other mutants. Sundberg JP, Vogel P, and Ward JM, eds., Wiley. Begley D, Schofield PN, Sundberg JP. The Mouse Online: Open Mouse Biology and Pathology Data Resources for Biomedical Research. (2022) 6-21.</li> <li>MMHCdb presented at the 19th Annual Workshop on the Pathology of Mouse Models for Human Disease, "Mouse Genome Informatics (MGI) and Mouse Models of Human Cancer Databases". (September 2021)</li> </ul> (<a href="whatsNew.jsp">View all...</a>) </div> </section> </main> <footer> <div class="container"> <div> <div class="footer-logo"> <p>Hosted by</p> <a href="https://www.jax.org"> <img src="/_res/img/logo-mono.png" alt="The Jackson Laboratory"> </a> </div> <div class="footer-logo"> <p>Part of Mouse Genome Informatics</p> <a href="http://www.informatics.jax.org" style="top:-10px;"><img src="/_res/img/mgi-logo-2.png" alt="Mouse Genome Informatics" style="max-width:170px;"></a> </div> <div> <p><a href="/mtbwi/citation.jsp">Citing This Resource</a></p> <p><a href="/mtbwi/funding.jsp">Funding Information</a></p> <p><a href="/mtbwi/copyright.jsp">Warranty Disclaimer & Copyright Notice</a></p> <p>Send questions and comments to <a href="http://www.informatics.jax.org/mgihome/support/mgi_inbox.shtml">MGI User Support</a>.</p> </div> <div> <h6>Last Software Update</h6> <p>2023-01-04 | version Date: 2024-06-20 Version: 6.0 RockyOS Public </p> <h6>Last Data Update</h6> <p>2025-02-16</p> </div></div> </div> </footer> <script type="text/javascript" id="mod-loader"> (function () { var i, l, u, s, c, modLoader, jp, cp, modLoader = document.getElementById('mod-loader'), docHead = document.getElementsByTagName('head')[0], jsPath = '/_res/js/', cssPath = '/_res/css/', sf = [], cf = []; if (typeof mods !== 'undefined' && Array.isArray(mods) && mods.length > 0) { u = {}; for (i = 0, l = mods.length; i < l; i += 1) { if (!u.hasOwnProperty(mods[i])) { if (/^[\.\/]/.test(mods[i])) { jp = ''; cp = ''; } else { jp = jsPath; cp = cssPath; } if (/\.js$/.test(mods[i])) { sf.push(jp + mods[i]); } else if (/\.css$/.test(mods[i])) { cf.push(cp + mods[i]); } else { sf.push(jp + mods[i] + '.js'); cf.push(cp + mods[i] + '.css'); } u[mods[i]] = 1; } } } for (i = 0, l = sf.length; i < l; i += 1) { s = document.createElement('script'); s.type = 'text/javascript'; s.async = false; s.src = sf[i]; modLoader.parentNode.insertBefore(s, modLoader); } for (i = 0, l = cf.length; i < l; i += 1) { c = document.createElement('link'); c.type = 'text/css'; c.rel = 'stylesheet'; c.href = cf[i]; docHead.appendChild(c); } })(); </script> </body> </html>