Phage Display Library Construction Services

<!DOCTYPE html> <html lang="en-us"> <head><meta http-equiv="Content-Type" content="text/html; charset=utf-8" /><meta charset="utf-8" /><meta http-equiv="X-UA-Compatible" content="IE=edge" /><meta name="viewport" content="width=device-width, initial-scale=1" /><title> Phage Display Library Construction Services - Creative Biolabs </title> <base href="/" /> <link rel="icon" href="static/images/favicon.png" type="image/x-icon" />  <link rel="stylesheet" type="text/css" href="static/css/key.css?t=D20190703" /><link rel="preconnect" href="https://www.googletagmanager.com" /><link rel="preconnect" href="https://bat.bing.com" /><link rel="preconnect" href="https://www.cblcdn.com" /><link rel="canonical" href="https://www.creative-biolabs.com/phage-display-library-construction.html" /> <link rel="stylesheet" type="text/css" href="static/css/style-services.min.css?t=D20190703" /> <link rel="stylesheet" type="text/css" href="static/css/style-podcast.min.css?t=D20190703" /> <link rel="stylesheet" type="text/css" href="static/css/style-inquiry.min.css?t=D20190703" /> <style> .inquiry_arera { padding-top: 30px; padding-bottom: 30px; background-color: #f2f2f2; display: block; } .inquiry_arera div[class*="col"] { padding-top: 5px; padding-bottom: 5px; } span.inq-icon-but { background: linear-gradient(to right, #c45160,#f0924c ) !important; color: #fff; text-align: center; font-weight: bold; padding:7px 50px 7px 10px; display: inline-block; cursor: pointer; position: relative; } span.inq-icon-but::after{ content:""; position: absolute; background-image: url('../static/images/5-120601154058-50.gif'); top:6px; right:10px; width:30px; height:30px; background-repeat: no-repeat; background-position: center; } .inqpagebut span.inq-icon-but::after{ content:"→" !important; background-image:none !important; top:8px !important; font-size:20px; } .inqpagebut{display: block;padding-top:30px !important;padding-bottom:30px !important; text-align: center;} span.inq-icon-but:hover { background-color: linear-gradient(to right, #f0924c,#c45160 ) !important; color: #fff; } .inq_bg { position: fixed; top: 0px; left: 0; background-color: rgba(0,0,0,0.7); width: 100%; height: 100%; z-index: 1100; align-items: center; justify-content: center; display: none; } .inq_bg .inqfor { background-color: #fff; padding: 20px; border-radius: 10px; position: relative; margin: 4% auto auto auto; } .inq_bg .inqfor .clos { width: 40px; height: 40px; top: 0; right: 0px; position: absolute; display: inline-block; line-height: 40px; text-align: center; font-size: 24px; z-index: 1000; cursor: pointer; } @media (min-width:769px) { .inq_bg .inqfor { width: 60%; } .inqfor div[class*="col-md"]:nth-child(1),.inqfor div[class*="col-md"]:nth-child(2),.inqfor div[class*="col-md"]:nth-child(3){ width:33.3% !important; } } @media (max-width:768px) { .inq_bg .inqfor { width: 90%; overflow-y: scroll; } } </style> <script>dataLayer = [{"ip":"8.222.208.146","c_session_id":"51A7D33C683A493E0C247B936BFF9E70","c_user_id":"51A7D33C683A493E0C247B936BFF9E70"}];</script>  <script>(function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start': new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0], j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src= 'https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f); })(window,document,'script','dataLayer','GTM-MD8987');</script> <meta name="description" content="Creative Biolabs is pleased to offer customized library construction services under a variety of phage display systems." /><meta name="keywords" content="phage display library construction, filamentous bacteriophages M13 T4 T7, peptide, protein, scaffold, cDNA" /></head> <body>  <noscript><iframe src="https://www.googletagmanager.com/ns.html?id=GTM-MD8987&ip=8.222.208.146&c_session_id=51A7D33C683A493E0C247B936BFF9E70&c_user_id=51A7D33C683A493E0C247B936BFF9E70" height="0" width="0" style="display:none;visibility:hidden"></iframe></noscript>  <div class="autoheader"> <div class="topad_pic" style="display: block;">  <a href="https://events.creative-biolabs.com" id="ad_exhibition" rel="nofollow" aria-label="Meet Us at the Upcoming Events"> <div class="source-img-box"> </div> </a> </div> <div id="header"> <a href="/"> <img src="static/images/biolabs.com-1921x690-color.png" srcset="static/images/biolabs.com-1921x690-color.webp 1x, static/images/biolabs.com-1921x690-color.webp 2x, static/images/biolabs.com-1921x690-color.webp 3x" id="logo" width="120" height="60" alt="Creative biolabs"></a> <div class="navMenu"> <span><i class="fa fa-bars"></i>MENU</span> <span><i class="fa fa-search"></i>SEARCH</span> </div> </div> </div> <div class="nav_bg" style="background-color: rgba(0,0,0,0.6);"></div> <div class="menuShow"> <span class="menuclosed"><i class="fa fa-times"></i>Close</span> <div class="mennav"> <ul style="position: relative;"> <li> <span>Discovery</span> <div class="secondMenu"> <div class="second-menu-area-box"> <ul style="margin-top:0;">  <li class="col-md-8 col-lg-8 col-sm-8"> <ul class="navi-menu-2 MenuList"><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="By Technology">By Technology</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/phage-display-service.html" title="Phage Display based Binder Discovery">Phage Display based Binder Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/phage-display-library-construction.html" title="Phage Display Library Construction">Phage Display Library Construction</a></li><li class="navi-menu-li-4"><a href="/phage-display-library-screening.html" title="Phage Display Library Screening">Phage Display Library Screening</a></li></ul></li><li class="navi-menu-li-3"><a href="/yeast-display-services.html" title="Yeast Display based Binder Discovery">Yeast Display based Binder Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/yeast-display-library-construction-services.html" title="Yeast Display Library Construction">Yeast Display Library Construction</a></li><li class="navi-menu-li-4"><a href="/yeast-display-library-screening-services.html" title="Yeast Display Library Screening">Yeast Display Library Screening</a></li></ul></li><li class="navi-menu-li-3"><a href="/premade-library-based-binder-discovery-services.html" title="Premade Library based Binder Discovery">Premade Library based Binder Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="javascript:void(0)" title="Premade Library Licensing">Premade Library Licensing</a><ul class="navi-menu-5 three_menu"><li class="navi-menu-li-5"><a href="/premade-human-and-mouse-antibody-libraries.html" title="Premade Antibody Library">Premade Antibody Library</a></li><li class="navi-menu-li-5"><a href="/premade-phage-display-peptide-libraries.html" title="Premade Peptide Library">Premade Peptide Library</a></li><li class="navi-menu-li-5"><a href="/Premade-single-domain-antibody-library.html" title="Premade SdAb Library">Premade SdAb Library</a></li><li class="navi-menu-li-5"><a href="/Immunized-Human-Antibody-Library.html" title="Immune Human Antibody Library">Immune Human Antibody Library</a></li></ul></li><li class="navi-menu-li-4"><a href="/premade-phage-display-antibody-library-screening-service.html" title="Premade Antibody Library Screening">Premade Antibody Library Screening</a></li><li class="navi-menu-li-4"><a href="/premade-single-domain-antibody-library-screening-service.html" title="Premade Single Domain Antibody (SdAb) Library Screening">Premade Single Domain Antibody (SdAb) Library Screening</a></li><li class="navi-menu-li-4"><a href="/premade-phage-display-peptide-library-screening-service.html" title="Premade Peptide Library Screening">Premade Peptide Library Screening</a></li></ul></li><li class="navi-menu-li-3"><a href="/Native-TM-Antibody-Discovery-Service.html" title="Single B Cell Sorting based Antibody Discovery">Single B Cell Sorting based Antibody Discovery</a></li><li class="navi-menu-li-3"><a href="/custom-antibody-development.html" title="Hybridoma based Antibody Discovery">Hybridoma based Antibody Discovery</a></li><li class="navi-menu-li-3"><a href="/Human-Antibody-Production-from-Transgenic-Mice.html" title="Transgenic Mice based Human Antibody Discovery">Transgenic Mice based Human Antibody Discovery</a></li><li class="navi-menu-li-3"><a href="/biomolecular-interaction-analysis-services.html" title="Biomolecular Interaction based Binder Discovery">Biomolecular Interaction based Binder Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/yeast-two-hybrid-y2h-service.html" title="Yeast Two-Hybrid (Y2H)">Yeast Two-Hybrid (Y2H)</a></li><li class="navi-menu-li-4"><a href="/bacterial-two-hybrid-b2h-service.html" title="Bacterial Two-Hybrid (B2H)">Bacterial Two-Hybrid (B2H)</a></li></ul></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="By Binder">By Binder</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/sdab-single-domain-antibody.html" title="Single Domain Antibody (SdAb) Discovery">Single Domain Antibody (SdAb) Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/single-domain-antibody-library-service.html" title="SdAb Library Construction & Screening">SdAb Library Construction & Screening</a></li><li class="navi-menu-li-4"><a href="/human-or-humanized-sdab-production.html" title="Human/Humanized SdAb Discovery">Human/Humanized SdAb Discovery</a></li><li class="navi-menu-li-4"><a href="/bispecific-sdab-production.html" title="Bispecific SdAb Discovery">Bispecific SdAb Discovery</a></li></ul></li><li class="navi-menu-li-3"><a href="/immune-antibody-library-services.html" title="Monoclonal Antibody Discovery">Monoclonal Antibody Discovery</a></li><li class="navi-menu-li-3"><a href="/discovery-services.html" title="Polyclonal Antibody Discovery">Polyclonal Antibody Discovery</a></li><li class="navi-menu-li-3"><a href="/Engineered-Protein-Scaffold-Library-Construction-Service.html" title="Scaffold Discovery">Scaffold Discovery</a></li><li class="navi-menu-li-3"><a href="/Magic-Bioactive-Peptides-Discovery-Service.htm" title="Peptide Discovery">Peptide Discovery</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="By Target">By Target</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/membrane-protein-service.html" title="Membrane Protein Specific Antibody Discovery">Membrane Protein Specific Antibody Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/membrane-protein-preparation-as-antigen-for-antibody-discovery.html" title="Membrane Protein Antigen Preparation">Membrane Protein Antigen Preparation</a></li><li class="navi-menu-li-4"><a href="/MemProArt-TM-anti-GPCR-Antibody-Production.html" title="GPCR Specific Antibody Discovery">GPCR Specific Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/MemProArt-TM-anti-Ion-Channel-Antibody-Production.html" title="Ion Channel Specific Antibody Discovery">Ion Channel Specific Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/MemProArt-TM-anti-transporter-Antibody-Production.html" title="Transporter Specific Antibody Discovery">Transporter Specific Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/sdab-discovery-against-membrane-proteins-by-dna-immunization.html" title="Membrane Protein Specific Single Domain Antibody (SdAb) Discovery">Membrane Protein Specific Single Domain Antibody (SdAb) Discovery</a></li></ul></li><li class="navi-menu-li-3"><a href="/Custom-antibody-services-for-post-translational-modification-specific-antibody-discovery.html" title="Post-Translational Modification (PTM) Specific Antibody Discovery">Post-Translational Modification (PTM) Specific Antibody Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/Phosphorylation-Specific-Antibody-Production-Services.html" title="Phosphorylation Specific Antibody Discovery">Phosphorylation Specific Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/Acetylation-Specific-Antibody-Production-Services.html" title="Acetylation Specific Antibody Discovery">Acetylation Specific Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/Methylation-Specific-Antibody-Production-Services.html" title="Methylation Specific Antibody Discovery">Methylation Specific Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/Ubiquitination-Specific-Antibody-Production-Service.html" title="Ubiquitination Specific Antibody Discovery">Ubiquitination Specific Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/fatty-acylation-specific-antibody-production-services.html" title="Fatty Acylation (Myristoylation, Palmitoylation) Specific Antibody Discovery">Fatty Acylation (Myristoylation, Palmitoylation) Specific Antibody Discovery</a></li></ul></li><li class="navi-menu-li-3"><a href="/Production-of-Anti-idiotype-Antibody.html" title="Idiotype Specific Antibody Discovery">Idiotype Specific Antibody Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/Anti-Idiotypic-Antibodies-Production-service-detecting-FREE-antibodies.html" title="FREE Antibody recognized Anti-ID Antibody Discovery">FREE Antibody recognized Anti-ID Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/Anti-Idiotypic-Antibodies-Prodution-detecting-TOTAL-antibodiese.html" title="TOTAL Antibody recognized Anti-ID Antibody Discovery">TOTAL Antibody recognized Anti-ID Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/Anti-Idiotypic-Antibodies-Production-service-detecting-BOUND-antibodies.html" title="BOUND Antibody recognized Anti-ID Antibody Discovery">BOUND Antibody recognized Anti-ID Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/Anti-Idiotypic-Antibodies-Production-service-detecting-T-cell-receptors.html" title="T Cell Receptor recognized Anti-ID Antibody Discovery">T Cell Receptor recognized Anti-ID Antibody Discovery</a></li><li class="navi-menu-li-4"><a href="/camel-anti-idiotypic-antibodies-sdabs-production-service.html" title="Idiotype Specific Single Domain Antibody (SdAb) Discovery">Idiotype Specific Single Domain Antibody (SdAb) Discovery</a></li></ul></li><li class="navi-menu-li-3"><a href="/anti-hapten-antibody-development-service.html" title="Hapten Specific Antibody Discovery">Hapten Specific Antibody Discovery</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="By Application">By Application</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="javascript:void(0)" title="Stable Binder Discovery">Stable Binder Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/thermal-stable-mabs-discovery-services.html" title="Thermal Stable mAb Discovery">Thermal Stable mAb Discovery</a></li><li class="navi-menu-li-4"><a href="/Thermal-Stable-scFv-Fab-Screening.html" title="Thermal Stable ScFv/Fab Discovery">Thermal Stable ScFv/Fab Discovery</a></li><li class="navi-menu-li-4"><a href="/thermal-stable-vhh-screening.html" title="Thermal Stable SdAb Discovery">Thermal Stable SdAb Discovery</a></li></ul></li><li class="navi-menu-li-3"><a href="/ph-sensitive-biomolecules-discovery-services.html" title="pH-Sensitive Binder Discovery">pH-Sensitive Binder Discovery</a></li><li class="navi-menu-li-3"><a href="/Screening-for-Internalizing-Antibodies-and-Peptides.html" title="Internalizing Antibody Discovery">Internalizing Antibody Discovery</a></li><li class="navi-menu-li-3"><a href="/Super-TM-Intrabody-Generation.html" title="Intrabody Discovery">Intrabody Discovery</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/intrabody-discovery-service.html" title="SdAb based Intrabody Discovery">SdAb based Intrabody Discovery</a></li></ul></li><li class="navi-menu-li-3"><a href="/Agonistic-Antibody-Discovery-Service.html" title="Agonistic/Antagonistic Antibody Discovery">Agonistic/Antagonistic Antibody Discovery</a></li></ul></li></ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit">Services</b> <p class="open-sans-light"> Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects. </p>  <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-1.jpg" srcset="static/images/Solutions-menu-lights-pic-1.webp 1x" width="201" height="131" loading="lazy"><a href="discovery-services.html" class="bannerbutton"><i class="fa fa-angle-right"></i>Discovery Services</a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-2.jpg" srcset="static/images/Solutions-menu-lights-pic-2.webp 1x" width="201" height="131" loading="lazy"><a href="engineering-services.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>Engineering Services </a> </li> </ul> </li> </ul> </div> </div> </li> <li> <span>Characterization</span> <div class="secondMenu"> <div class="second-menu-area-box"> <ul style="margin-top:0;">  <li class="col-md-8 col-lg-8 col-sm-8"> <ul class="navi-menu-2 MenuList"><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="Binding Analysis">Binding Analysis</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/Antibody-Affinity-Measurement.html" title="Affinity Measurement">Affinity Measurement</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/Affinity-Measurement-Services-for-Specific-Antibodies.html" title="Antibody Affinity Measurement">Antibody Affinity Measurement</a></li><li class="navi-menu-li-4"><a href="/Membrane-Proteins-Affinity-Measurement.html" title="Membrane Protein Affinity Measurement">Membrane Protein Affinity Measurement</a></li><li class="navi-menu-li-4"><a href="/Affinity-Measurement-Services-for-Small-Molecules.html" title="Small Molecule Affinity Measurement">Small Molecule Affinity Measurement</a></li></ul></li><li class="navi-menu-li-3"><a href="/precision-paratope-mapping-service.htm" title="Paratope Mapping">Paratope Mapping</a></li><li class="navi-menu-li-3"><a href="/Monoclonal-Antibody-Epitope-Binning.html" title="Epitope Binning">Epitope Binning</a></li><li class="navi-menu-li-3"><a href="/cremap.html" title="Epitope Mapping">Epitope Mapping</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/cremap-b-cell-epitope-mapping-service.html" title="B Cell Epitope Mapping">B Cell Epitope Mapping</a></li><li class="navi-menu-li-4"><a href="/cremap-t-cell-epitope-discovery-service.html" title="T Cell Epitope Discovery">T Cell Epitope Discovery</a></li></ul></li><li class="navi-menu-li-3"><a href="/high-throughput-membrane-protein-array-screening-services.html" title="Antibody Off-Target Identification & Specificity Profiling">Antibody Off-Target Identification & Specificity Profiling</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="Sequence Analysis">Sequence Analysis</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/next-generation-antibody-sequencing.html" title="<i>De Novo</i> Sequencing"><i>De Novo</i> Sequencing</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/De-Novo-Human-Humanized-Antibody-Sequencing-Service.html" title="Human/Humanized Antibody Sequencing">Human/Humanized Antibody Sequencing</a></li><li class="navi-menu-li-4"><a href="/De-Novo-Biosimilar-monoclonal-antibodies-Sequencing-Service.html" title="Biosimilar mAb Sequencing">Biosimilar mAb Sequencing</a></li><li class="navi-menu-li-4"><a href="/de-novo-sdab-sequencing-service.html" title="Single Domain Antibody (SdAb) Sequencing">Single Domain Antibody (SdAb) Sequencing</a></li><li class="navi-menu-li-4"><a href="/De-Novo-Rodent-Antibody-Sequencing-Service.html" title="Rodent Antibody Sequencing">Rodent Antibody Sequencing</a></li><li class="navi-menu-li-4"><a href="/De-Novo-Rabbit-Antibody-Sequencing-Service.html" title="Rabbit Antibody Sequencing">Rabbit Antibody Sequencing</a></li><li class="navi-menu-li-4"><a href="/De-Novo-Chicken-IgYs-Sequencing-Service.html" title="Chicken IgY Sequencing">Chicken IgY Sequencing</a></li><li class="navi-menu-li-4"><a href="/De-Novo-TCR-T-cell-Receptor-Sequencing-Service.html" title="T Cell Receptor (TCR) Sequencing">T Cell Receptor (TCR) Sequencing</a></li></ul></li><li class="navi-menu-li-3"><a href="/antibody-sequencing-service.html" title="Hybridoma Sequencing">Hybridoma Sequencing</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/immunologic-analysis-services.html" title="Immunogenicity Analysis">Immunogenicity Analysis</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/SIAT.html" title="Immunogenicity Assessment">Immunogenicity Assessment</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/in-silico-Immunogenicity-Assessment.html" title="<i>In Silico</i> Assessment"><i>In Silico</i> Assessment</a></li><li class="navi-menu-li-4"><a href="/ex-vivo-Immunogenicity-Assessment.html" title="<i>Ex Vivo</i> Assessment"><i>Ex Vivo</i> Assessment</a></li><li class="navi-menu-li-4"><a href="/in-vivo-Immunogenicity-Assessment.html" title="<i>In Vivo</i> Assessment"><i>In Vivo</i> Assessment</a></li><li class="navi-menu-li-4"><a href="/Anti-drug-Antibodies-ADA-Assays.html" title="Anti-Drug Antibodies (ADA) Assay">Anti-Drug Antibodies (ADA) Assay</a></li></ul></li><li class="navi-menu-li-3"><a href="/Magic-Therapeutic-Antibody-Discovery-Service.htm" title="Repertoire Analysis">Repertoire Analysis</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/magic-bcr-repertoire-analysis.html" title="BCR Repertoire Analysis">BCR Repertoire Analysis</a></li><li class="navi-menu-li-4"><a href="/magic-tcr-repertoire-sequencing-service.html" title="TCR Repertoire Analysis">TCR Repertoire Analysis</a></li></ul></li><li class="navi-menu-li-3"><a href="/ecia.html" title="Cellular Analysis">Cellular Analysis</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/hla-tissue-typing.html" title="HLA Tissue Typing">HLA Tissue Typing</a></li><li class="navi-menu-li-4"><a href="/ecia-b-cell-elispot-assay.html" title="B Cell ELISpot">B Cell ELISpot</a></li><li class="navi-menu-li-4"><a href="/ecia-t-cell-elispot-assay.html" title="T Cell ELISpot">T Cell ELISpot</a></li></ul></li><li class="navi-menu-li-3"><a href="/De-immunogenicity-De-immunization.html" title="De-immunization">De-immunization</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/Antibody-Analysis-Services.html" title="Property Analysis">Property Analysis</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/Isothermal-Titration-Calorimetry-ITC-Service.html" title="ITC Assessment">ITC Assessment</a></li><li class="navi-menu-li-3"><a href="/Differential-scanning-calorimetry-DSC-Service.html" title="DSC Assessment">DSC Assessment</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/drug-discovery/therapeutics/antibody-function-assays.htm" title="Functional Analysis">Functional Analysis</a></li></ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit">Services</b> <p class="open-sans-light"> Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects. </p>  <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-1.jpg" srcset="static/images/Solutions-menu-lights-pic-1.webp 1x" width="201" height="131" loading="lazy"><a href="discovery-services.html" class="bannerbutton"><i class="fa fa-angle-right"></i>Discovery Services</a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-2.jpg" srcset="static/images/Solutions-menu-lights-pic-2.webp 1x" width="201" height="131" loading="lazy"><a href="engineering-services.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>Engineering Services </a> </li> </ul> </li> </ul> </div> </div> </li> <li> <span>Engineering</span> <div class="secondMenu"> <div class="second-menu-area-box"> <ul style="margin-top:0;">  <li class="col-md-8 col-lg-8 col-sm-8"> <ul class="navi-menu-2 MenuList"><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/Antibody-Engineering-Services.html" title="Antibody Conversion">Antibody Conversion</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/Human-or-Humanized-Antibody-Services.html" title="Humanization (Convert to Human Ab)">Humanization (Convert to Human Ab)</a></li><li class="navi-menu-li-3"><a href="/Antibody-Camelization-Services.html" title="Camelization (Convert to Single Domain Ab)">Camelization (Convert to Single Domain Ab)</a></li><li class="navi-menu-li-3"><a href="/Antibody-Caninization-Service.html" title="Caninization (Convert to Dog Ab)">Caninization (Convert to Dog Ab)</a></li><li class="navi-menu-li-3"><a href="/Simianization-of-Non-monkey-Antibodies.html" title="Simianization (Convert to NHP Ab)">Simianization (Convert to NHP Ab)</a></li><li class="navi-menu-li-3"><a href="/Antibody-Murinization-Service.html" title="Murinization (Convert to Mouse Ab)">Murinization (Convert to Mouse Ab)</a></li><li class="navi-menu-li-3"><a href="/chimeric-IgG-generation.html" title="Chimeric Antibody Conversion">Chimeric Antibody Conversion</a></li><li class="navi-menu-li-3"><a href="/scfv-fab-generation.html" title="ScFv/Fab Conversion">ScFv/Fab Conversion</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/engineering-services.html" title="Property Optimization">Property Optimization</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/antibody-affinity-maturation.html" title="Affinity Maturation">Affinity Maturation</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/sdab-affinity-maturation.html" title="Single Domain Antibody (SdAb) Affinity Maturation">Single Domain Antibody (SdAb) Affinity Maturation</a></li></ul></li><li class="navi-menu-li-3"><a href="/Antibody-Stability-Improvement.html" title="Stability Improvement">Stability Improvement</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/single-domain-antibody-stability-improvement-service.html" title="Single Domain Antibody (SdAb) Stability Improvement">Single Domain Antibody (SdAb) Stability Improvement</a></li></ul></li><li class="navi-menu-li-3"><a href="/scaffold-specificity-optimization-service.html" title="Specificity Optimization">Specificity Optimization</a></li><li class="navi-menu-li-3"><a href="/Custom-Cysteine-Modification-in-Antibody.html" title="Cysteine Modification">Cysteine Modification</a></li><li class="navi-menu-li-3"><a href="/yeast-display-based-t-cell-receptor-engineering-service.html" title="T Cell Receptor Engineering">T Cell Receptor Engineering</a></li><li class="navi-menu-li-3"><a href="/drug-discovery/therapeutics/fc-engineering-service.htm" title="Fc Engineering">Fc Engineering</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/bioconjugation/" title="Labeling/Conjugation">Labeling/Conjugation</a></li></ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit">Services</b> <p class="open-sans-light"> Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects. </p>  <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-1.jpg" srcset="static/images/Solutions-menu-lights-pic-1.webp 1x" width="201" height="131" loading="lazy"><a href="discovery-services.html" class="bannerbutton"><i class="fa fa-angle-right"></i>Discovery Services</a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-2.jpg" srcset="static/images/Solutions-menu-lights-pic-2.webp 1x" width="201" height="131" loading="lazy"><a href="engineering-services.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>Engineering Services </a> </li> </ul> </li> </ul> </div> </div> </li> <li> <span>Custom Production & Manufacturing</span> <div class="secondMenu"> <div class="second-menu-area-box"> <ul style="margin-top:0;">  <li class="col-md-8 col-lg-8 col-sm-8"> <ul class="navi-menu-2 MenuList"><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="Custom Production">Custom Production</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="javascript:void(0)" title="Membrane Protein Preparation">Membrane Protein Preparation</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/Custom-GPCR-Production-Service.html" title="GPCR Preparation">GPCR Preparation</a></li><li class="navi-menu-li-4"><a href="/Custom-Ion-Channel-Protein-Production-Service.html" title="Ion Channel Preparation">Ion Channel Preparation</a></li><li class="navi-menu-li-4"><a href="/Membrane-Transport-Proteins.html" title="Transporter Preparation">Transporter Preparation</a></li><li class="navi-menu-li-4"><a href="/Membrane-Protein-Production.html" title="Custom Membrane Protein Production">Custom Membrane Protein Production</a></li><li class="navi-menu-li-4"><a href="/magic-membrane-protein-solubilization-and-stabilization.html" title="Custom Membrane Protein Solubilization and Stabilization">Custom Membrane Protein Solubilization and Stabilization</a></li><li class="navi-menu-li-4"><a href="/magic-membrane-protein-functional-validation.html" title="Custom Membrane Protein QC">Custom Membrane Protein QC</a></li></ul></li><li class="navi-menu-li-3"><a href="/Virus-like-Particles.html" title="Virus Like Particle (VLP) Production">Virus Like Particle (VLP) Production</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/virus-like-particles-vlps-production-in-insect-cell-system.html" title="Insect Cell based VLP Production">Insect Cell based VLP Production</a></li><li class="navi-menu-li-4"><a href="/virus-like-particles-vlps-production-in-mammalian-cell-system.html" title="Mammalian Cell based VLP Production">Mammalian Cell based VLP Production</a></li><li class="navi-menu-li-4"><a href="/virus-like-particles-vlps-production-in-e-coli-system.html" title="<i>E. coli</i> based VLP Production"><i>E. coli</i> based VLP Production</a></li><li class="navi-menu-li-4"><a href="/virus-like-particles-vlps-production-in-yeast-cell-system.html" title="Yeast Cell based VLP Production">Yeast Cell based VLP Production</a></li><li class="navi-menu-li-4"><a href="/virus-like-particles-vlps-production-in-plant-system.html" title="Plant Cell based VLP Production">Plant Cell based VLP Production</a></li></ul></li><li class="navi-menu-li-3"><a href="/Antibody-Production-Services.html" title="Recombinant Antibody Production">Recombinant Antibody Production</a></li><li class="navi-menu-li-3"><a href="/bulk-antibody-production-by-ascites.html" title="Ascites Fluid based Antibody Production">Ascites Fluid based Antibody Production</a></li><li class="navi-menu-li-3"><a href="/Stable-Cell-Line-Services.html" title="Stable Cell Line Construction">Stable Cell Line Construction</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/bio-manufacturing.html" title="Manufacturing">Manufacturing</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/Manufacturability-Assessment.htm" title="Manufacturability Assessment and Optimization">Manufacturability Assessment and Optimization</a><ul class="navi-menu-4 three_menu"><li class="navi-menu-li-4"><a href="/virtual-prediction-of-manufacturability-assessment-and-improvement.html" title="Virtual Prediction">Virtual Prediction</a></li><li class="navi-menu-li-4"><a href="/amino-acid-sequence-and-terminal-sequence-analysis.html" title="Amino Acid & Terminal Sequence Analysis">Amino Acid & Terminal Sequence Analysis</a></li></ul></li></ul></li></ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit">Services</b> <p class="open-sans-light"> Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects. </p>  <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-1.jpg" srcset="static/images/Solutions-menu-lights-pic-1.webp 1x" width="201" height="131" loading="lazy"><a href="discovery-services.html" class="bannerbutton"><i class="fa fa-angle-right"></i>Discovery Services</a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Solutions-menu-lights-pic-2.jpg" srcset="static/images/Solutions-menu-lights-pic-2.webp 1x" width="201" height="131" loading="lazy"><a href="engineering-services.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>Engineering Services </a> </li> </ul> </li> </ul> </div> </div> </li> <li> <span>Products</span> <div class="secondMenu"> <div class="second-menu-area-box"> <ul style="margin-top:0;"> <li class="col-md-8 col-lg-8 col-sm-8"> <ul class="navi-menu-2 MenuList"><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/category-premade-phage-display-library-ready-to-use-kits-4.htm" title="Phage Display Library Ready-To-Use Kits">Phage Display Library Ready-To-Use Kits</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/category-premade-yeast-display-library-ready-to-use-kits-6.htm" title="Yeast Display Library Ready-To-Use Kits">Yeast Display Library Ready-To-Use Kits</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/category-recombinant-antibody-products-2.htm" title="Recombinant Antibody Products">Recombinant Antibody Products</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/category-membrane-protein-products-11.htm" title="Membrane Protein Products">Membrane Protein Products</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/category-nativeextract-membrane-protein-products-38.htm" title="Full-Length Membrane Protein (Super Nanodisc)">Full-Length Membrane Protein (Super Nanodisc)</a></li><li class="navi-menu-li-3"><a href="/category-gpcrs-protein-products-20.htm" title="GPCR Protein">GPCR Protein</a></li><li class="navi-menu-li-3"><a href="/category-transporter-protein-products-21.htm" title="Transporter Protein">Transporter Protein</a></li><li class="navi-menu-li-3"><a href="/category-ion-channel-protein-products-22.htm" title="Ion Channel Protein">Ion Channel Protein</a></li><li class="navi-menu-li-3"><a href="/category-car-t-therapy-target-protein-products-23.htm" title="CAR-T Therapy Target Protein">CAR-T Therapy Target Protein</a></li><li class="navi-menu-li-3"><a href="/category-biomarkers-and-cd-protein-products-24.htm" title="Biomarkers and CD Protein">Biomarkers and CD Protein</a></li><li class="navi-menu-li-3"><a href="/category-fc-receptor-protein-products-25.htm" title="Fc Receptor Protein">Fc Receptor Protein</a></li><li class="navi-menu-li-3"><a href="/category-hla-protein-products-26.htm" title="HLA Protein">HLA Protein</a></li><li class="navi-menu-li-3"><a href="/category-cell-free-protein-products-27.htm" title="Cell-Free Protein">Cell-Free Protein</a></li><li class="navi-menu-li-3"><a href="/category-mp-vlps-products-28.htm" title="MP-VLP">MP-VLP</a></li><li class="navi-menu-li-3"><a href="/category-other-membrane-protein-products-29.htm" title="Other Membrane Protein">Other Membrane Protein</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/category-membrane-protein-expression-kits-30.htm" title="Membrane Protein Expression Kits">Membrane Protein Expression Kits</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/category-magic-cell-free-membrane-protein-expression-kits-32.htm" title="Cell-Free Membrane Protein Expression Kits">Cell-Free Membrane Protein Expression Kits</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/category-membrane-protein-solubilization-and-stabilization-reagents-33.htm" title="Membrane Protein Solubilization & Stabilization Reagents">Membrane Protein Solubilization & Stabilization Reagents</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/category-detergents-34.htm" title="Detergent">Detergent</a></li><li class="navi-menu-li-3"><a href="/category-phospholipids-35.htm" title="Phospholipid">Phospholipid</a></li><li class="navi-menu-li-3"><a href="/category-nanodiscs-36.htm" title="Nanodisc">Nanodisc</a></li><li class="navi-menu-li-3"><a href="/category-polymer-37.htm" title="Polymer">Polymer</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/category-membrane-protein-stable-cell-line-products-10.htm" title="Membrane Protein Stable Cell Line Products">Membrane Protein Stable Cell Line Products</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/adc/classify-products-5.htm" title="Antibody-Drug Conjugate (ADC) Products">Antibody-Drug Conjugate (ADC) Products</a></li></ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit">Products</b><p class="open-sans-light"> With over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. </p> <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Products-menu-lights-pic-1.jpg" srcset="static/images/Products-menu-lights-pic-1.webp 1x" width="200" height="131" loading="lazy"><a href="Premade-single-domain-antibody-library.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>sdAb Libraries </a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Products-menu-lights-pic-2.jpg" srcset="static/images/Products-menu-lights-pic-2.webp 1x" width="200" height="131" loading="lazy"><a href="Immunized-Human-Antibody-Library.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>Immunized hAb Libraries </a> </li> </ul> </li> </ul> </div> </div> </li> <li> <span>Platforms</span> <div class="secondMenu"> <div class="second-menu-area-box"> <ul style="margin-top:0;"> <li class="col-md-8 col-lg-8 col-sm-8"> <ul class="navi-menu-2 MenuList"><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/Phage-Display-Platform.html" title="Phage Display Platform">Phage Display Platform</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/yeast-display-platform.html" title="Yeast Display Platform">Yeast Display Platform</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/Hybridoma-Platform.html" title="Hybridoma Platform">Hybridoma Platform</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/b-cell-sorting-platform.html" title="Single B Cell Sorting Platform">Single B Cell Sorting Platform</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/Membrane-Protein-Platform.html" title="Membrane Protein Platform">Membrane Protein Platform</a></li></ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit"> Platforms </b> <p class="open-sans-light"> Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects. </p>  <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Platforms-menu-lights-pic-1.jpg" srcset="static/images/Platforms-menu-lights-pic-1.webp 1x" width="201" height="131" loading="lazy"><a href="b-cell-sorting-platform.html" class="bannerbutton"><i class="fa fa-angle-right"></i>B-Cell Sorting Platform</a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Platforms-menu-lights-pic-2.jpg" srcset="static/images/Platforms-menu-lights-pic-2.webp 1x" width="201" height="131" loading="lazy"><a href="Phage-Display-Platform.html" class="bannerbutton"><i class="fa fa-angle-right"></i>Phage Display Platform</a> </li> </ul> </li> </ul> </div> </div> </li> <li> <span>Resources</span> <div class="secondMenu"> <div class="second-menu-area-box">  <ul style="margin-top:0;"> <li class="col-md-8 col-lg-8 col-sm-8"> <ul class="navi-menu-2 MenuList"><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/Peer-reviewed-Publications.html" title="Peer-Reviewed Publications">Peer-Reviewed Publications</a></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/faq.htm" title="Frequently Asked Questions (FAQs)">Frequently Asked Questions (FAQs)</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/antibody-antigen-faq.htm" title="Antibody & Antigen FAQ">Antibody & Antigen FAQ</a></li><li class="navi-menu-li-3"><a href="/surface-technology-faq.html" title="Surface Technology FAQ">Surface Technology FAQ</a></li><li class="navi-menu-li-3"><a href="/antibody-service-faq.html" title="Antibody Service FAQ">Antibody Service FAQ</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="Resource Download">Resource Download</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/conference-resources.html" title="Conference Resources">Conference Resources</a></li><li class="navi-menu-li-3"><a href="/support-documents.html" title="Support Documents">Support Documents</a></li><li class="navi-menu-li-3"><a href="/newsletter.aspx" title="Newsletter">Newsletter</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/knowledge-center.html" title="Knowledge Hub">Knowledge Hub</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/protocol.html" title="Protocol Instances">Protocol Instances</a></li><li class="navi-menu-li-3"><a href="/technology-introductions.html" title="Technology Introductions">Technology Introductions</a></li><li class="navi-menu-li-3"><a href="/background-knowledges.html" title="Background Knowledges">Background Knowledges</a></li><li class="navi-menu-li-3"><a href="/antibody-overviews.html" title="Antibody Overviews">Antibody Overviews</a></li><li class="navi-menu-li-3"><a href="/membrane-protein-types-introduction.html" title="Membrane Protein Overviews">Membrane Protein Overviews</a></li><li class="navi-menu-li-3"><a href="/scaffold-overviews.html" title="Scaffold Overviews">Scaffold Overviews</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="javascript:void(0)" title="Host Spot Insight">Host Spot Insight</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/literature.html" title="Literature Review">Literature Review</a></li><li class="navi-menu-li-3"><a href="/hot-topics.html" title="Hot Topics">Hot Topics</a></li></ul></li><li class="navi-menu-li-2 col-md-4 col-lg-4 col-sm-4"><a href="/podcast.html" title="Podcast">Podcast</a><ul class="navi-menu-3 three_menu"><li class="navi-menu-li-3"><a href="/surface-display-technology-podcasts.html" title="Surface Display Technology">Surface Display Technology</a></li><li class="navi-menu-li-3"><a href="/recombinant-antibody.html" title="Recombinant Antibody">Recombinant Antibody</a></li><li class="navi-menu-li-3"><a href="/therapeutic-antibody.html" title="Therapeutic Antibody">Therapeutic Antibody</a></li><li class="navi-menu-li-3"><a href="/de-novo-antibody-sequencing.html" title="<i>De Novo</i> Antibody Sequencing"><i>De Novo</i> Antibody Sequencing</a></li><li class="navi-menu-li-3"><a href="/membrane-protein.html" title="Membrane Protein">Membrane Protein</a></li></ul></li></ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit"> Resources </b> <p class="open-sans-light"> With deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions. </p>  <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Resources-menu-lights-pic-1.jpg" srcset="static/images/Resources-menu-lights-pic-1.webp 1x" width="201" height="131" loading="lazy"><a href="Peer-reviewed-Publications.html" class="bannerbutton"><i class="fa fa-angle-right"></i>Peer-Reviewed Publications</a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Resources-menu-lights-pic-2.jpg" srcset="static/images/Resources-menu-lights-pic-2.webp 1x" width="201" height="131" loading="lazy"><a href="support-documents.html" class="bannerbutton"><i class="fa fa-angle-right"></i>Support Documents</a> </li> </ul> </li> </ul> </div> </div> </li> <li> <span>Company</span> <div class="secondMenu"> <div class="second-menu-area-box"> <ul style="margin-top:0;">  <li class="col-md-8 col-lg-8 col-sm-8"> <ul class=" MenuList"> <li class="col-md-4 col-lg-4 col-sm-4"><a href="aboutus.html" rel="nofollow">About Creative Biolabs</a> <ul class="navi-menu-2 three_menu"> <li class="navi-menu-li-2"><a href="/Licensing-and-Collaboration.html" title="Licensing and Collaboration">Licensing and Collaboration</a></li> </ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"><a href="contactus.html" rel="nofollow">Contact Us</a></li> <li class="col-md-4 col-lg-4 col-sm-4"><a href="Distributors.html" rel="nofollow">Distributors</a></li> <li class="col-md-4 col-lg-4 col-sm-4"><a href="feedback.aspx">Reviews & Endorsements</a></li> <li class="col-md-4 col-lg-4 col-sm-4"><a href="/career/career.aspx" rel="nofollow">Careers</a> </li> <li class="col-md-4 col-lg-4 col-sm-4"><a href="https://events.creative-biolabs.com" rel="nofollow">Events</a></li> <li class="col-md-4 col-lg-4 col-sm-4"><a href="scholarship-program.html">Scholarship Program</a></li> <li class="col-md-4 col-lg-4 col-sm-4"><a href="creative-biolabs-corporate-social-responsibility.html">Corporate Social Responsibility</a></li> </ul> </li> <li class="col-md-4 col-lg-4 col-sm-4"> <b class="Highlights_tit"> About Us </b> <p class="open-sans-light"> Get a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects. </p> <b class="Highlights_tit">Highlights</b> <ul class="HighlightsArea"> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Abouts-menu-lights-pic-1.jpg" srcset="static/images/Abouts-menu-lights-pic-1.webp 1x" width="200" height="131" loading="lazy"><a href="aboutus.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>About CBL </a> </li> <li class="col-md-6 col-lg-6 col-sm-6"> <img src="static/images/Abouts-menu-lights-pic-2.jpg" srcset="static/images/Abouts-menu-lights-pic-2.webp 1x" width="200" height="131" loading="lazy"><a href="contactus.html" class="bannerbutton"> <i class="fa fa-angle-right"></i>Contact Us </a> </li> </ul> </li> </ul> </div> </div> </li> </ul> <script> window.addEventListener('load',function(){ var arr = ['/drug-discovery/therapeutics/','/bioconjugation/','/adc/']; $('.mennav ul li a').each(function(){ var $this = $(this); var href = $this.attr("href").toLocaleLowerCase(); $.each(arr, function(index, value) { if (href && href.startsWith(value)) { $this.attr('target', '_blank'); } }); }); }); </script> </div> <div class="top-search search-group"> <div class="col-md-5 col-sm-6"> <label class="radio-inline"><input type="radio" name="search" class="rdo_productsearch" value="product" data-type="product" placeholder="Please input cat#, product name, abbr, or keywords."> Product</label> <label class="radio-inline"><input type="radio" name="search" class="rdo_servicesearch" value="service" data-type="service" placeholder="Please input your keywords."> Service</label> <label class="radio-inline"><input type="radio" name="search" class="rdo_googlesearch" value="google" data-type="google" placeholder="Please input your keywords." checked="checked"> Keyword</label> </div> <div class="col-md-7 col-sm-6 search-div"> <input id="keys" name="keys" placeholder="Please input your keywords." class="search-input"> <div class="selectItems"></div> <span class="search_btn"><i class="fa fa-search"></i></span> </div> </div> </div> <div class="searchShow"> <div class="searchtopbg"></div> <span class="searchclosed"><i class="fa fa-times"></i>Close</span> <div class="addsearch search-group"></div> </div> <div class="banner_inpage services_bg_2"> <div class="auto-container small_content-width about_container"> <ul class="bread-crumb clearfix"> <li><a href="/">Home</a></li> <li><a href="javascrpt:void(0)">Discovery</a></li><li><a href="javascrpt:void(0)">By Technology</a></li><li><a href="/phage-display-service.html">Phage Display based Binder Discovery</a></li> <li>Phage Display Library Construction</li> </ul> <p>"Creative Biolabs is committed to providing highly customized comprehensive solutions with the best quality to advance our global clients’ projects."</p> </div> </div> <script> window.addEventListener('load', function () { if (($('.bread-crumb li:last-child').text()) == "Peer-Reviewed Publications") { $(".banner_inpage").addClass("peer-reviewed-publications_bg").removeClass("services_bg_2"); } if ($(window).hasClass('bread-crumb')) { if ($(".bread-crumb").html().indexOf("RESOURCE") > -1) { $(".pronote").hide(); } if ($(".bread-crumb").html().indexOf("Careers") > -1) { $(".pronote").hide(); } } }); </script> <div class="small_content-width services-container"> <div class="col-md-12"> <div class="inpage_section_title"> <h1>Phage Display Library Construction Services</h1> </div> <div class="page-tab"> <span onclick="window.location.href=window.location.pathname+'#tab1'">Background</span> <span onclick="window.location.href=window.location.pathname+'#tab2'">Library Types</span> <span onclick="window.location.href=window.location.pathname+'#tab3'">Construction Process</span> <span onclick="window.location.href=window.location.pathname+'#tab4'">(Semi-)Synthetic Libraries</span> <span onclick="window.location.href=window.location.pathname+'#tab5'">Phage Display Systems</span> <span onclick="window.location.href=window.location.pathname+'#tab6'">Applications</span><span onclick="window.location.href=window.location.pathname+'#tab7'">Why Creative Biolabs?</span> <span onclick="window.location.href=window.location.pathname+'#tab8'">FAQ</span> <span onclick="window.location.href=window.location.pathname+'#tab9'">Resources</span> <span class="inq-icon-but">Online Inquiry </span> </div> <script>window.addEventListener('load',function(){page_tab_css();page_tab_margin();})</script> <p> <strong>Creative Biolabs</strong> offers advanced phage display library construction services, including the development of custom libraries for antibody, scaffold, peptide, and cDNA formats. With extensive experience in constructing high-diversity libraries, Creative Biolabs ensures efficient identification of high-affinity binders tailored for therapeutic, diagnostic, and research applications. Their services include immune and naïve libraries in formats such as Fab, scFv, and V<sub>H</sub>H. With a commitment to quality and innovation, Creative Biolabs delivers high-performance solutions designed to accelerate your antibody development pipeline. </p> <p class="inqpagebut"> <span class="inq-icon-but">Online Inquiry</span> </p> <h2 class="h2_tit page_tab_margin" id="tab1"> What is Phage Display Library? </h2> <p> Phage display library is a cutting-edge technique that allows for the expression of peptides, antibodies, or proteins on the surface of bacteriophages. By fusing genetic sequences of interest into the phage genome, the proteins are displayed on the outer surface, where they can interact with target molecules such as antigens or receptors. This technique is valuable for high-throughput screening, enabling the rapid identification of high-affinity binders for therapeutic, diagnostic, or research purposes. </p> <p> Phage display revolutionizes antibody discovery by linking the genotype of the displayed molecule with its phenotype, allowing for the efficient identification of specific binders. This has made it an indispensable tool in developing drugs, diagnostics, and other bioactive molecules. The diversity of phage display libraries, which can reach over 10 billion unique clones, ensures that the chance of discovering rare, high-affinity binders is significantly increased. </p> <p> In the pharmaceutical industry, phage display libraries accelerate drug discovery, allowing for the efficient identification of therapeutic antibodies. Similarly, in the field of diagnostics, phage display libraries can identify biomarkers that are vital for the early detection of diseases. This broad applicability has made phage display an indispensable tool in various sectors, from cancer research to infectious diseases. </p> <h2 class="h2_tit page_tab_margin" id="tab2"> Creative Biolabs' Phage Display Library Types </h2> <p> Creative Biolabs offers a range of phage display library construction services, each designed to meet the needs of different research areas: </p> <h3> <a href="immune-antibody-library-services.html">Antibody Libraries</a> (<a href="immune-antibody-library-introduction.html">Immune</a>, <a href="naive-antibody-library-introduction.html">Naïve</a>, <a href="semi-synthetic-antibody-library-introduction.html">Semi-Synthetic</a>, <a href="synthetic-antibody-library-introduction.html">Synthetic</a>) </h3> <p> Creative Biolabs can display the interested antibody in either scFv, Fab or V<sub>H</sub>H format to construct a high-quality antibody library. Due to the smaller size, V<sub>H</sub>H and scFv libraries are genetically more stable than Fab libraries, Fab libraries lack the tendency to form higher molecular weight species, such as dimers and trimers, which can simplify the selection and characterization. Moreover, both human plasma cells and splenocytes from naïve or immune animals can be accepted as repertoire sources for our antibody library construction service. In addition, Creative Biolabs is able to generate fully or semi-synthetic antibody libraries as well. </p> <ul class="ullist"> <li> <strong><a href="premade-human-and-mouse-antibody-libraries.html">ScFv (Single-Chain Variable Fragment) Libraries</a></strong> </li> </ul> <p> Creative Biolabs constructs scFv libraries that display antibody fragments consisting of the variable regions of both heavy and light chains connected by a short peptide linker. scFv libraries are particularly advantageous due to their small size, which enhances their genetic stability and allows for easier manipulation and expression. These libraries are ideal for discovering antibodies with high affinity and specificity, making them suitable for therapeutic, diagnostic, and research applications. The scFv fragments identified through Creative Biolabs' phage display services can also be easily engineered into full-length IgG, <a href="bispecific-antibody-services.html">bispecific antibodies</a>, <a href="antibody-discovery-for-car-t-therapy-from-premade-phage-displayed-antibody-library.html">CAR-T</a> constructs, or <a href="antibody-discovery-for-adc-therapy-from-premade-phage-displayed-antibody-library.html">ADCs</a>. </p> <ul class="ullist"> <li> <strong><a href="premade-human-and-mouse-antibody-libraries.html">Fab (Fragment Antigen-Binding) Libraries</a></strong> </li> </ul> <p> The Fab libraries provided by Creative Biolabs offer another powerful format for antibody discovery. Fab fragments consist of one light chain and one heavy chain fragment, retaining the antigen-binding specificity of a full antibody. Fab fragments are larger than scFvs, but they lack the Fc region, making them useful in applications where Fc-mediated effects, such as immune system activation, need to be avoided. Fab libraries are a preferred format for diagnostic applications and therapeutic development, particularly when high specificity and affinity are required. The Fab format simplifies selection, characterization, and engineering into other therapeutic formats. </p> <ul class="ullist"> <li> <strong><a href="sdab-single-domain-antibody.html">V<sub>H</sub>H (Single Domain Antibody) Libraries</a></strong> </li> </ul> <p> Creative Biolabs also offers single domain antibody (sdAb) libraries, which are derived from camelid antibodies. V<sub>H</sub>H are unique antibody fragments that possess several advantages due to their small size, high stability, and ability to bind to cryptic or challenging epitopes. These characteristics make V<sub>H</sub>Hs particularly useful in drug discovery, especially for targeting inaccessible antigens or in therapeutic areas where deep tissue penetration is essential. Creative Biolabs' V<sub>H</sub>H libraries provide a versatile platform for discovering sdAbs with high affinity and specificity for challenging targets. </p> <ul class="ullist"> <li> <strong>Fully Synthetic and Semi-Synthetic Antibody Libraries</strong> </li> </ul> <p> For projects requiring fully synthetic or semi-synthetic antibody libraries, Creative Biolabs employs cutting-edge techniques to design libraries with tailored diversity. These libraries can be constructed to explore specific sequences or to mimic natural antibody repertoires, making them ideal for discovering antibodies against novel or rare targets. With advanced randomization methods, these libraries offer high diversity and can be optimized for developability, including factors like thermostability and reduced immunogenicity. </p> <h3> <a href="Engineered-Protein-Scaffold-Library-Construction-Service.html">Scaffold Libraries</a> </h3> <p> Creative Biolabs is able to generate high-quality phage display libraries for a comprehensive list of scaffolds. Our scientists are devoted to offering customized services to design specific scaffolds based on clients' demands. In addition, to achieve 100% precise mutant and over 10<sup>10</sup> diversity, both trimer codon technology and NNK method are used in the library construction resulting in an increased randomicity, which enables the library to be more suitable for sorting and isolating the high-affinity protein or peptide targets. </p> <h3> <a href="Constrained-Peptide-Library-Construction.html">Peptide Libraries (Naïve, Semi-synthetic)</a> </h3> <p> To form a peptide library, Creative Biolabs can generate constrained structures with target-adapted cross-links for both naïve and semi-synthetic peptides. This structure contributes to maintaining or increasing a series of properties of peptides, such as stability, permeability, binding affinity, and resistance to protease activity. </p> <h3> <a href="cdna-library-construction-service.html">cDNA Libraries</a> </h3> <p> According to our advanced phage display platform, Creative Biolabs is capable of displaying entire cDNA products on the surface of appropriate phage system. Compared with conventional cDNA libraries, our high-quality libraries can achieve higher capacity, density, and correct orientation, which further contribute to the investigation of a lot of protein candidates. Moreover, there are various types of cDNA libraries, including standard library, full-length library, normalized library, and subtractive library, can be tailored to match our clients' demands. </p> <h2 class="h2_tit page_tab_margin" id="tab3"> Phage Display Library Construction & Screening Process </h2> <p> The process of phage display library construction and screening involves several key steps, which can be customized based on the specific needs of a project. Below is an overview of the general process involved in discovering a novel binder: </p> <ul class="ullist"> <li> <strong>Repertoire Sourcing</strong>: Sourcing the genetic material from either plasma cells, splenocytes, or synthetic DNA. </li> <li> <strong>Library Cloning</strong>: Inserting the DNA sequences into the phage genome for display on the phage surface. </li> <li> <strong>Panning</strong>: Repeated rounds of selection to enrich phages that bind to the target molecule. </li> <li> <strong>Screening</strong>: Identifying phages with the highest affinity and specificity to the target. </li> <li> <strong>Characterization</strong>: Further biochemical and structural characterization of the selected binders. </li> </ul> <p class="show-center"> <img loading="lazy" src="static/img/1-1-1-1-phage-display-library-construction-fig2.jpg" width="500" height="307" alt="Fig. 1 Phage display library construction process. (Creative Biolabs Original)" />Fig. 1 Phage display library construction and screening </p> <p> Creative Biolabs ensures the use of high-throughput screening methods to identify the most suitable candidates for the client's needs. Their use of advanced cloning and selection technologies guarantees the production of high-quality libraries with high diversity. </p> <h2 class="h2_tit page_tab_margin" id="tab4"> Diversity of Semi-synthetic/Synthetic Libraries </h2> <p> In general, Creative Biolabs employs three main approaches to design semi-synthetic or fully synthetic libraries with appropriate diversity. Our scientists normally generate libraries with a diversity of 108, while we are also able to generate libraries over 10<sup>10</sup> or follow our clients' specific requirements. </p> <ul class="ullist"> <li> <strong>Hard randomization:</strong> complete diversity is introduced by using degenerate codons encoding all twenty natural amino acids. </li> <li> <strong>Tailored randomization:</strong> incomplete or biased diversity is introduced by using degenerate codons encoding a subset of natural amino acids. </li> <li> <strong>Diversification:</strong> degenerate codons are synthesized using trimer phosphoramidites corresponding to 20 natural amino acids, which exclude stop codons. </li> </ul> <h2 class="h2_tit page_tab_margin" id="tab5"> Phage Display Systems </h2> <p> Based on the interest protein and specific project objective, Creative Biolabs is able to tailor the most suitable phage display system (M13, T4, or T7) for the library construction. </p> <ul class="ullist"> <li> <strong><a href="m13-phage-library-construction-service.html">M13 Phage Library Construction</a></strong> </li> <li> <strong><a href="t4-phage-library-construction-services.html">T4 Phage Library Construction</a></strong> </li> <li> <strong><a href="t7-phage-library-construction-service.html">T7 Phage Library Construction</a></strong> </li> </ul> <p class="show-center"> <img loading="lazy" src="static/img/1-1-1-1-phage-display-library-construction-fig1.jpg" width="600" height="223" alt="Fig. 2 Schematic diagram of phage structure. (Creative Biolabs Original)" />Fig. 2 Phage: Structure and genome </p> <p align="center"> Table 1. Typical phage display systems. </p> <div class=" table-responsive"> <table style="margin:auto;" class=" tableContentShow" width="80%" cellspacing="0" cellpadding="0" border="1"> <tbody> <tr> <td width="25%"> </td> <td width="25%"> <strong>M13</strong> </td> <td width="25%"> <strong>T4</strong> </td> <td width="25%"> <strong>T7</strong> </td> </tr> <tr> <td> <strong>Genome Size</strong> </td> <td> 6,407 bp </td> <td> 168,895 bp </td> <td> 39,937 bp </td> </tr> <tr> <td> <strong>Display Protein</strong> </td> <td> pIII & pVIII </td> <td> SOC & HOC </td> <td> gp10B </td> </tr> <tr> <td> <strong>Display Size</strong> </td> <td> >110 kDa on pIII<br /> <10 kDa on pVIII </td> <td> <710 kDa </td> <td> <132 kDa </td> </tr> <tr> <td> <strong>Display Density</strong> </td> <td> <5 copies on pIII<br /> <2,700 copies on pVIII </td> <td> <810 copies on SOC<br /> <155 copies on HOC </td> <td> <415 copies </td> </tr> <tr> <td> <strong>Lifecycle</strong> </td> <td> Non-lytic </td> <td> Lytic </td> <td> Lytic </td> </tr> </tbody> </table> </div> <br /> <p> <strong>λ Phage</strong> </p> <p> In addition to regular M13, T7 or T4 phage, λ phage is an ideal vehicle to carry the DNA fragments due to its simple structure and flexible DNA. By employing multiple lambda vectors, Creative Biolabs can offer specific <a href="genome-library-construction-service-via-lambda-phage.html">genome library construction service</a> to generate qualified genome library with over 95% coverage from either genomic DNA, chromosomes, or microbes. In addition, our professional scientists are also available to generate lambda-based cDNA library as an alternative service. </p> <div class=" table-responsive"> <table style="margin:auto;" class=" tableContentShow" width="80%" cellspacing="0" cellpadding="0" border="1"> <tbody> <tr> <td width="25%"> <strong>Phage Display System</strong> </td> <td width="25%"> <strong>Characteristics</strong> </td> <td width="25%"> <strong>Advantages</strong> </td> <td width="25%"> <strong>Applications</strong> </td> </tr> <tr> <td> <strong>M13 Phage Display</strong> </td> <td> Multivalent display of peptides and antibodies </td> <td> Ideal for screening small peptides and antibody fragments </td> <td> Antibody discovery, epitope mapping </td> </tr> <tr> <td> <strong>T4 Phage Display</strong> </td> <td> Efficient large protein display using head or tail </td> <td> High structural stability, suited for large antigens </td> <td> Vaccine development, multivalent antigen presentation </td> </tr> <tr> <td> <strong>T7 Phage Display</strong> </td> <td> Efficient display of large peptides and proteins </td> <td> High expression efficiency for complex antigens </td> <td> Vaccine development, therapeutic target identification </td> </tr> <tr> <td> <strong>Lambda Phage Display</strong> </td> <td> Large protein fragment display </td> <td> Best for protein-protein interaction studies </td> <td> Functional protein studies, large antigen screening </td> </tr> </tbody> </table> </div> <h2 class="h2_tit page_tab_margin" id="tab6"> Different Applications of Phage Display Library Construction Service </h2> <p> <strong>Therapeutic Antibody Discovery</strong>: Phage display libraries allow for the rapid identification of antibodies that specifically target disease-causing proteins, such as those found in cancer, autoimmune diseases, and infectious diseases. Creative Biolabs leverages both naïve and immune antibody libraries to provide tailored solutions, ensuring high diversity and developability. By using our advanced library construction technologies, we enable clients to rapidly progress from discovery to preclinical development, ensuring that therapeutic antibodies are ready for downstream applications. </p> <p> <strong>Diagnostic Development</strong>: Creative Biolabs' diagnostic-focused phage display services are tailored to ensure the development of high-affinity antibodies for diagnostic kits. Our expertise in antibody engineering ensures that the antibodies developed through phage display are optimized for diagnostic performance. </p> <p> <strong>Basic Research</strong>: Phage display libraries enable researchers to study protein-protein, protein-DNA, and protein-ligand interactions, contributing to a deeper understanding of cellular processes and disease mechanisms. This foundational research is crucial for the identification of novel therapeutic targets and biomarkers. Creative Biolabs supports basic research applications by offering customizable phage display services that meet the unique needs of research projects. Our high-diversity libraries, combined with expert guidance, allow researchers to explore complex biological interactions and advance the understanding of molecular mechanisms. </p> <h2 class="h2_tit page_tab_margin" id="tab7"> Why Choose Creative Biolabs? </h2> <p> Creative Biolabs offers unmatched expertise in phage display library construction, with over 20 years of experience in the field. Our team of specialists provides personalized service, working closely with clients to design and implement projects that meet their specific research needs. Our proprietary technologies, large-scale custom libraries, and full project support make us a trusted partner in the discovery and development of antibodies, peptides, and proteins for therapeutic and diagnostic applications. </p> <p class="inqpagebut"> <span class="inq-icon-but">Talk to Our Antibody Expert</span> </p> <h2 class="h2_tit page_tab_margin" id="tab8"> FAQ </h2> <script type="text/javascript"> window.addEventListener('load',function(){ faqlist(4); }); </script> <ol class="ollist faqlist"> <li> <span class="sFAQTit">What is the principle of phage display technology?</span> <p> Phage display technology fuses and displays exogenous peptides and phage capsid proteins on the surface of phages, performs high-throughput screening and enrichment, and conducts qualitative analysis of clones with required functions. The display objects of this technology are antibodies, antibody fragments, peptides, cDNA, and so on. </p> </li> <li> <span class="sFAQTit">What are the advantages of phage display in the construction of antibody libraries?</span> <p> In the study of antibody libraries, phage display technology can construct and screen the B cell antibody libraries of humans and other animals <em>in vitro</em>, avoiding the steps of immunity and cell fusion so as to shorten the experimental cycle and increase stability. The technology also has the advantages of large screening capacity, mass fermentation production, simple experimental method, and so on. </p> </li> <li> <span class="sFAQTit">What research directions can phage display technology be applied to?</span> <p> According to the different display molecules, it can be roughly divided into the following two categories:<br /> 1) Protein/antibody: diagnostics, drug navigation, protein structure analysis, humanized modification, and customization of scientific research antibodies.<br /> 2) Random peptide library: protein-protein (ligand receptor, information transmission, antagonist/inhibitor, <em>etc</em>.), protein-DNA, diagnostics, neutralization activity, drug and drug navigation, enzyme, and substrate. </p> </li> <li> <span class="sFAQTit">What are the screening methods for phage display?</span> <p> There are two main screening methods for phage display: magnetic bead labeling and immune tube screening. The difference between the two is that the former has more positive clones, while the latter has fewer positive clones but higher affinity. In general, the magnetic bead labeling method is preferred for screening, and then it is decided whether or not to increase the immune tube screening step according to the results. The basic principle of the two methods is the specific binding of antigens and antibodies. </p> </li> <li> <span class="sFAQTit">How can the screening process displayed by bacteriophages ensure that the antibodies that are screened for interference can retain the desired antibodies?</span> <p> The principle of selection is actually an experimental process based on the specific reaction between antigens and antibodies. Specifically, the specific binding between the antibody sequence displayed on the surface of the phage and the antigen makes the specific antibody sequence continuously enriched. However, in the process of screening, there must be non-specific binding between bacteriophages of 10<sup>12</sup> or higher and antigens, so after the screening is over, another ELISA identification will be carried out to exclude the non-specific binding antibody clones. Secondly, if there are several highly homologous targets that need to be distinguished at the same time, a closed group can be set up to seal off the cross-binding positive clones in advance, and the remaining phage library can be used to screen specific targets. </p> </li> <li> <span class="sFAQTit">How much will be detected by monoclonal clone sequencing in the phage antibody library?</span> <p> For the evaluation of the antibody library, 20–50 clones are randomly selected and sequenced to evaluate the diversity and titer of antibodies.<br /> For the positive clones after screening and ELISA detection, the 10-15 clones with the best ELISA results are generally selected for sequencing. </p> </li> <li> <span class="sFAQTit">What is the capacity of the phage antibody library finally obtained? How to ensure that the coverage meets the requirements after repackaging?</span> <p> Finally, the phage antibody library was 20–30 ml, and each tube of 1 ml was assembled separately. In general, as long as the number of clones in each tube is more than ten times the capacity of the library, all the sequences can be guaranteed. If the capacity of the immune antibody library is 10<sup>9</sup>, as long as the concentration of bacterial liquid in each tube is more than 10<sup>10</sup>, all antibody sequences can be covered. </p> </li> </ol> <h2 class="h2_tit page_tab_margin" id="tab9"> Resources </h2> <p> Use the resources in our library to help you understand your options and make critical decisions for your study. </p> <div class="tab_nav"> <span class="tab_choosebg">Videos</span> <span>Podcasts</span> <span>Infographic</span> <span>Flyer</span> <span>Case study</span> <span>Articles</span> </div>  <div class="tab_cont" style="display:block;"> <div class="row pagerow_pt"> <div class="col-md-4"> <div class="pagerow_pt_unit"> <img loading="lazy" src="../static/img/video-phage-display-technology.png" alt="Phage Display Technology" /> </div> <a href="https://youtu.be/mczJ3ZbpVW8" target="_blank">Phage Display Technology</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit"> <img loading="lazy" src="../static/img/video-development-of-monoclonal-antibodies-s.png" alt="Antibody Library Screening" /> </div> <a href="https://youtu.be/NGqipRkxXiY" target="_blank">Antibody Library Screening</a> </div> </div> </div>  <div class="tab_cont"> <div class="therapy_ad"> <a href="surface-display-technology-podcasts.html"> <img loading="lazy" src="../static/img/podcasts-ad.png" width="1600" height="300" srcset="../static/img/podcasts-ad.webp 1x,../static/img/podcasts-ad.webp 2x,../static/img/podcasts-ad.webp 3x" alt="In this brand new podcast series, we will show you everything you want to know about CAR-T therapy, including the mechanism, current applications, technology limitations, and potential strategies." /></a> </div> </div>  <div class="tab_cont"> <div class="row pagerow_pt"> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/paghe-display-1.jpg" width="600" height="500" alt="Phage Display Technology" /> </div> <a href="https://go.creative-biolabs.com/phage-display-infographic.html">Phage Display Technology</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/Antibody-Library-Screening-Creative-Biolabs.jpg" width="600" height="500" alt="Antibody Library Screening" /> </div> <a href="https://go.creative-biolabs.com/antibody-library-screening.html">Antibody Library Screening</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/Development-of-Monoclonal-Antibodies-1.jpg" width="600" height="500" alt="Development of Monoclonal Antibodies" /> </div> <a href="https://go.creative-biolabs.com/development-of-monoclonal-antibodies.html">Development of Monoclonal Antibodies</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/A-Brief-Introduction-to-Antibodies-1.jpg" width="600" height="500" alt="A Brief Introduction to Antibodies" /> </div> <a href="https://go.creative-biolabs.com/a-brief-introduction-to-antibodies.html">A Brief Introduction to Antibodies</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/Anti-idiotypic-Antibody.jpg" width="600" height="500" alt="Anti-idiotype Antibody Production" /> </div> <a href="https://go.creative-biolabs.com/anti-idiotype-antibody-production.html">Anti-idiotype Antibody Production</a> </div> </div> </div>  <div class="tab_cont"> <div class="row pagerow_pt"> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/Phage-Display-Technology-Flyer-Creative-Biolabs.jpg" width="600" height="500" alt="Phage Display Technology in Creative Biolabs" /> </div> <a href="/resource/pdf/com/flyers/Phage-Display-Technology-Flyer-Creative-Biolabs.pdf">Phage Display Technology in Creative Biolabs</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/Immune-Phage-Display-Library-Construction-and-Screening-Flyer-Creative-Biolabs.jpg" width="600" height="500" alt="Antibody Development by Immune Phage Library" /> </div> <a href="/resource/pdf/com/flyers/Immune-Phage-Display-Library-Construction-and-Screening-Flyer-Creative-Biolabs.pdf">Antibody Development by Immune Phage Library</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/Magic-Therapeutic-Antibody-Discovery-Platform-Flyer-Creative-Biolabs.jpg" width="600" height="500" alt="MagicTM Therapeutic Antibody Discovery Platform" /> </div> <a href="/resource/pdf/com/flyers/Magic-Therapeutic-Antibody-Discovery-Platform-Flyer-Creative-Biolabs.pdf">MagicTM Therapeutic Antibody Discovery Platform</a> </div> </div> </div>  <div class="tab_cont"> <div class="row pagerow_pt"> <div class="col-md-4"> <div class="pagerow_pt_unit_2"> <img loading="lazy" src="/resource/images/Antibody-Development-Case-Study-com.jpg" width="530" height="500" alt="Antibody Development Case Study" /> </div> <a href="https://go.creative-biolabs.com/antibody-development-case-study.html">Antibody Development Case Study</a> </div> </div> </div>  <div class="tab_cont"> <div class="row pagerow_pt"> <div class="col-md-4"> <div class="pagerow_pt_unit"> <img loading="lazy" src="../static/img/4-2-10-surface-display-overview-1.jpg" alt="Surface Display Overview" /> </div> <a href="surface-display-overview.html">Surface Display Overview</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit"> <img loading="lazy" src="../static/img/Phage-Display-Technology-as-a-Powerful-Platform-for-Antibody-Drug-Discovery-2.jpg" width="600" height="500" alt="Phage Display Technology as a Powerful Platform for Antibody Drug Discovery" /> </div> <a href="phage-display-technology-as-a-powerful-platform-for-antibody-drug-discovery.html">Phage Display Technology as a Powerful Platform for Antibody Drug Discovery</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit"> <img loading="lazy" src="../static/img/Basics-of-Antibody-Phage-Display-Technology-1.jpg" width="600" height="500" alt="Basics of Antibody Phage Display Technolog" /> </div> <a href="basics-of-antibody-phage-display-technology.html ">Basics of Antibody Phage Display Technolog</a> </div> <div class="col-md-4"> <div class="pagerow_pt_unit"> <img loading="lazy" src="../static/img/Immune-antibody-phage-libraries-1.jpg" width="600" height="500" alt="Immune Antibody Phage Libraries for the Production of Antibodies to Infectious Diseases" /> </div> <a href="immune-antibody-phage-libraries-for-the-production-of-antibodies-to-infectious-diseases.html ">Immune Antibody Phage Libraries for the Production of Antibodies to Infectious Diseases</a> </div> </div> </div> <script> window.addEventListener('load',function(){ // $(function () { $(".tab_nav span").click(function(){ var eqindex=$(this).index(); $(this).addClass("tab_choosebg"); $(this).siblings("span").removeClass("tab_choosebg"); $(".tab_cont").hide().eq(eqindex).show(); }) // }) }); </script> <style> .therapy_ad{position: relative;} .therapy_ad img{ max-width:100%; height:auto; display: block; margin:auto auto 20px auto; } </style><br> <p class="pronote"><i class="fa fa-exclamation-triangle"></i>All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.</p> <div class="related-sections"> <b>Related Sections</b> <b>Services</b> <ul class="related-sections-ul"> <li><a href="phage-display-service.html" >FAQ</a></li> <li><a href="/single-domain-antibody-library-service.html" >Single Domain Antibody (SdAb) Library Construction and Screening Service</a></li> <li><a href="/phage-display-library-screening.html" >Phage Display Library Screening Services</a></li> <li><a href="/antibody-humanization.html" >Rodent Antibody Humanization Service</a></li> <li><a href="/antibody-affinity-maturation.html" >Affinity Maturation Services</a></li> <li><a href="/High-Affi-TM-Human-Antibody-Discovery.html" >High-Affi™ Human Antibody Discovery Service</a></li> <li><a href="/full-human-antibody-from-humanized-mouse-derived-antibody-library.html" >Phage Display based Magic™ Human Antibody Discovery Service</a></li> <li><a href="/antibody-production-through-DNA-immunization-genetic-immunization.html" >DNA Immunization</a></li> </ul> <b>Products</b> <ul class="related-sections-ul"> <li><a href="/premade-phage-display-peptide-libraries.html" >Premade Peptide Library Licensing Service</a></li> <li><a href="/premade-human-and-mouse-antibody-libraries.html" >Premade Antibody Library Licensing Service</a></li> <li><a href="/Premade-single-domain-antibody-library.html" >Premade Single Domain Antibody (SdAb) Library Licensing Service</a></li> <li><a href="/Immunized-Human-Antibody-Library.html" >Immune Human Antibody Library Licensing Service</a></li> </ul> <b>Platform</b> <ul class="related-sections-ul"> <li><a href="/Phage-Display-Platform.html" >Phage Display Platform</a></li> </ul> </div> <div class="inq_bg"> <div class="inqfor"> <span class="clos">×</span> <div class="rig_tit">Online Inquiry</div> <link rel="preconnect" href="https://www.recaptcha.net" /> <style type="text/css">.grecaptcha-badge { opacity: 0; }</style> <script src="https://www.recaptcha.net/recaptcha/enterprise.js?render=6LdtbowmAAAAABp2LeBkVvRNBQvLXkSG5aExNWHk"></script> <script> function grecaptchaFormBinding(formName, callback, event, action='submit_form') { if (event != undefined) { event.preventDefault ? event.preventDefault() : (event.returnValue = false); } var _form = document.forms[formName]; if (_form != undefined) { grecaptcha.enterprise.ready(function () { grecaptcha.enterprise.execute('6LdtbowmAAAAABp2LeBkVvRNBQvLXkSG5aExNWHk', { action: action.length > 0 ? action : 'submit_form' }).then(function (token) { if (_form['g-recaptcha-response'] === undefined) { var _response_input = document.createElement('input'); _response_input.setAttribute('type', 'hidden'); _response_input.setAttribute('name', 'g-recaptcha-response'); _response_input.setAttribute('readonly', 'readonly'); _response_input.setAttribute('value', token); _form.appendChild(_response_input); } else { _form['g-recaptcha-response'].value = token; } if (callback != undefined) { callback(); } }); }); } } </script>  <script> window.addEventListener('load', function () { jQuery(document).ready(function () { jQuery("#formID").validationEngine("attach", { promptPosition: "bottomLeft", scroll: false, autoHidePrompt: true, autoHideDelay: 3000 }); // binds form submission and fields to the validation engine jQuery("#formID").validationEngine(); $("#formID").bind("jqv.form.validating", function (event) { $("#hookError").html(""); }); $("#formID").bind("jqv.form.result", function (event, errorFound) { if (errorFound) { $("#hookError").append("There is some problems with your form"); } }); $("#formID").submit(function (e) { if ($('#formID').validationEngine('validate')) { $(this).find(":submit").prop("disabled", true); grecaptchaFormBinding('orderform', function () { document.forms['orderform'].submit(); }, e); } //$(this).find(":submit").prop("disabled", false); e.preventDefault ? e.preventDefault() : (e.returnValue = false); return false; }); }); }); </script> <form role="form" id="formID" name="orderform" class="Inquiry_form" method="post" action="/form/pub.aspx" autocomplete="off"> <input type="hidden" id="inquirytoken" name="inquirytoken" value="2e1PwgtR" /> <input type="hidden" name="inquiryType" value="service"> <input type="hidden" name="cat" value=""> <input type="hidden" name="pn" value="" /> <input type="hidden" name="pn_url" value="" /> <div class="row"> <div class="col-md-12"> <label for="Phone">Name</label> <input type="text" placeholder="Name" name="I_Name" id="I_Name" /> </div> <div class="col-md-12"> <label for="Phone"><span class="red">*</span> Phone</label> <input type="text" name="I_Phone" id="I_Phone" placeholder="Phone" class="form-control input-md inputborderSecond validate[required] text-input" /> </div> <div class="col-md-12"> <label for="Email"><span class="red">*</span> Email</label> <input type="text" placeholder="Email" name="email" id="email" class="form-control input-md form-control inputborderSecond validate[required,custom[email]] text-input" /> </div> <div class="col-md-12"> <label><span class="red">*</span> Products or Services Interested:</label> <input type="text" name="I_Subject" id="I_Subject" placeholder="Products or Services Interested" value="Phage Display Library Construction Services" class="form-control input-md inputborderSecond validate[required] text-input" /> </div> <div class="col-md-12"> <label>Project Description</label> <textarea name="I_Message{EXT:[IEXT_Description]}" id="I_Message" placeholder="Project Description" cols="40" rows="4"></textarea> </div> <div class="col-md-12"> <input type="hidden" name="I_Codenumber" value="A" /> <input type="hidden" name="I_From Codenumber" value="" /> <button class="submit" type="submit">Send</button> <script src="https://static.creative-biolabs.com/_noindex/google-verification/verification.js" type="text/javascript"></script> <div style="clear: both;"></div> </div> </div> </form> </div> </div> <script> window.addEventListener('load', function () { function close_fun() { inqfor.slideUp("fast"); setTimeout(function () { inqbg.fadeOut("slow"); }, 400); } var inqbt = $(".inq-icon-but"); var inqbg = $(".inq_bg"); var inqfor = $(".inqfor"); var close_ = $(".clos"); inqbt.click(function () { inqbg.fadeIn(); setTimeout(function () { inqfor.slideDown(); }, 400); }) close_.click(function () { close_fun(); }) inqbg.click(function () { close_fun(); }) inqfor.on('click', function (event) { event.stopPropagation(); }); }) </script> </div> </div> <div class="promisebottom">Our customer service representatives are available 24 hours a day, 7 days a week. <a href="contactus.html" class="signup">Contact Us</a></div> <div class="contact_bottom"> <div class=" bottom_colum"> <div class="content-width"> <ul> <li> <b class="bottom_tit">Services<span></span></b> <ul> <li><a href="/phage-display-library-construction.html">Phage Display Library Construction</a></li> <li><a href="/phage-display-library-screening.html">Phage Display Library Screening</a></li> <li><a href="/Hybridoma-Services.html">Hybridoma Services</a></li> <li><a href="/Membrane-Protein-Service.html">Magic™ Anti-Membrane Protein Antibody Discovery</a></li> <li><a href="/Production-of-Anti-idiotype-Antibody.html">Anti-idiotype Antibody Discovery</a></li> <li><a href="/Nanobody-Single-Domain-Antibody.html">Single Domain Antibody (sdAb) Discovery</a></li> <li><a href="/Native-TM-Antibody-Discovery-Service.html">Native™ Antibody Discovery</a></li> <li><a href="/Next-Generation-Antibody-Sequencing.html"><em>De Novo</em> Antibody Sequencing</a></li> <li><a href="/antibody-humanization.html">Antibody Humanization</a></li> <li><a href="/antibody-affinity-maturation.html">Antibody Affinity Maturation</a></li> <li> <a href="/Custom-antibody-services-for-post-translational-modification-specific-antibody-discovery.html">Post-Translational Modification (PTM) Specific Antibody Discovery</a></li> </ul> </li> <li> <b class="bottom_tit">Platforms<span></span></b> <ul> <li><a href="Phage-Display-Platform.html">Phage Display Platform</a></li> <li><a href="Membrane-Protein-Platform.html">Membrane Protein Platform</a></li> <li><a href="hyperdoma-a-high-throughput-hybridoma-generation-platform.html">Hyperdoma™ Platform</a></li> <li><a href="b-cell-sorting-platform.html">B-Cell Sorting Platform</a></li> </ul> <b class="bottom_tit">Help & Support<span></span></b> <ul>  <li><a href="/faq.htm">Frequently Asked Questions (FAQs)</a></li> <li><a href="/support-documents.html">Support Documents</a></li> <li><a href="/knowledge-center.html">Knowledge Center</a></li> <li><a href="/newsletter.aspx">Newsletter</a></li> <li><a href="/protocol.html">Protocol</a></li> <li><a href="/literature.html">Literature</a></li> </ul> </li> <li class="bottom_contac_info"> <b class="bottom_tit">Contact us</b> <strong>USA</strong> <span cbl-addr-usa></span> <br> Tel: <span cbl-tel-usa1478></span> <br> Fax: <span cbl-fax></span> <br> Email: <a cbl-email class="a_link"></a> <strong>UK</strong> <span cbl-addr-uk></span> <br> Tel: <span cbl-tel-uk></span> <br> Email: <a cbl-email class="a_link"></a> <strong>Germany</strong> <span cbl-addr-germany></span> <br> Tel: <span cbl-tel-germany></span> <br> Email: <a cbl-email class="a_link"></a> </li> <li> <b class="bottom_tit">Subscribe to Our Newsletter for Updates:</b> <input type="text" class="letterinput" id="subscribeemail" placeholder="email@example.com"> <button type="button" class="newsletterbutton" onclick="javacript:subscribe('subscribeemail','Creative Biolabs','www.creative-biolabs.com')">Sign Up Now</button> <div class="iso"> <img src="https://www.cblcdn.com/images/ISO90012015.png" srcset="https://www.cblcdn.com/images/ISO90012015.webp 1x, https://www.cblcdn.com/images/ISO90012015.webp 2x, https://www.cblcdn.com/images/ISO90012015.webp 3x" width="200" alt="ISO 9001 Certified - Creative Biolabs Quality Management System" loading="lazy"> </div> </li> </ul> </div> </div> <script> window.addEventListener('load', function () { $(function () { var bottomspan=$(".bottom_tit span"); bottomspan.on("click",function(){ $(this).toggleClass("arrw"); $(this).parent(".bottom_tit").siblings("ul").toggle(100); }) }) }) </script> <div class="clear"></div> </div> <div class="indexfoot"> <div class="content-width"> <div class="col-md-9 col-sm-9 col-lg-9"> © 2024 Creative Biolabs. | <a href="contactus.html">Contact Us</a> </div> <link href="https://static.creative-biolabs.com/icon/style.css?v=1.0.202402" rel="stylesheet" type="text/css" /> <div class="col-md-3 col-sm-3 col-lg-3"> <span class="social-icon-two"> <a target="_blank" href="https://www.facebook.com/CreativeBiolabs" data-wow-duration="2s" aria-label="Learn more from facebook"><span class="icon-facebook"></span></a> <a target="_blank" href="https://twitter.com/CreativeBiolabs" aria-label="twitter"><span class="icon-twitter-x"></span></a> <a target="_blank" href="http://www.linkedin.com/company/creative-biolabs/" aria-label="Learn more from linkedin"><span class="icon-linkedin"></span></a> <a target="_blank" href="https://www.youtube.com/@CreativeBiolabs" aria-label="Learn more from youtube"><span class="icon-youtube"></span></a> <a target="_blank" href="/blog/" aria-label="Learn more from blog"><span class="icon-blogger"></span></a> </span> </div> </div> </div>  <link rel="stylesheet" type="text/css" href="static/css/public-new.css?t=D20190703" async> <link rel="stylesheet" type="text/css" href="static/css/bootstrap.min.css?t=D20190703" async> <link rel="stylesheet" type="text/css" href="static/css/fontawesome-all.min.css?t=D20190703" async> <script src="static/js/jquery-3.1.1.min.js"></script> <link href="/static/css/validationEngine.jquery.css" rel="stylesheet" async/> <script src="/static/js/jquery.validationEngine-en.js" async></script> <script src="/static/js/jquery.validationEngine.js" async></script> <script src="https://static.creative-biolabs.com/js/ahref.js" type="text/javascript" defer></script> <script> const loadContact = () => { if (typeof contactInformation !== 'undefined') new contactInformation({ opts: { messTags: ['cbl-addr-usa', 'cbl-tel-usa1478', 'cbl-tel-usa2254', 'cbl-tel-usa5530', 'cbl-tel-usa9819', 'cbl-fax', 'cbl-email', 'cbl-addr-uk', 'cbl-tel-uk', 'cbl-addr-germany', 'cbl-tel-germany' ], mainFix:"www.creative-biolabs.com" } }); } </script> <script src="https://www.cblcdn.com/_noindex/contact/base64Decryption.js" onload="loadContact();" async></script> <script src="static/js/navimenu.js" type="text/javascript" async></script> <script src="static/js/auto.js" type="text/javascript" async></script> <script src="static/js/base.js?v=1.0.05302" type="text/javascript" async></script> <script src="static/js/scrolltopcontrol.js" type="text/javascript" defer></script> <script> privacy_policy_config = {name: "3g7R9s", debug: true, url: "https://go.creative-biolabs.com/privacy-policy?website=com&domain=www.creative-biolabs.com&contact=marketemail_7b95a2ac8713cd7a3fdc04ba95ccdf9d"}; </script> <script src="https://www.cblcdn.com/_noindex/jquery.privacy.policy-v.js?v=1.0.202402" defer></script> </body> </html>

CINXE.COM

Phage Display Library Construction Services - Creative Biolabs