CINXE.COM

<!DOCTYPE html> <html lang="en" dir="ltr"> <head>  <script async src="https://www.googletagmanager.com/gtag/js?id=G-P63WKM1TM1"></script> <script> window.dataLayer = window.dataLayer || []; function gtag(){dataLayer.push(arguments);} gtag('js', new Date()); gtag('config', 'G-P63WKM1TM1'); </script>  <script type="text/javascript" > (function(m,e,t,r,i,k,a){m[i]=m[i]||function(){(m[i].a=m[i].a||[]).push(arguments)}; m[i].l=1*new Date(); for (var j = 0; j < document.scripts.length; j++) {if (document.scripts[j].src === r) { return; }} k=e.createElement(t),a=e.getElementsByTagName(t)[0],k.async=1,k.src=r,a.parentNode.insertBefore(k,a)}) (window, document, "script", "https://mc.yandex.ru/metrika/tag.js", "ym"); ym(55165297, "init", { clickmap:false, trackLinks:true, accurateTrackBounce:true, webvisor:false }); </script> <noscript><div><img src="https://mc.yandex.ru/watch/55165297" style="position:absolute; left:-9999px;" alt="" /></div></noscript>    <title>Search results for: Thibault Lachard</title> <meta name="description" content="Search results for: Thibault Lachard"> <meta name="keywords" content="Thibault Lachard"> <meta name="viewport" content="width=device-width, initial-scale=1, minimum-scale=1, maximum-scale=1, user-scalable=no"> <meta charset="utf-8"> <link href="https://cdn.waset.org/favicon.ico" type="image/x-icon" rel="shortcut icon"> <link href="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/css/bootstrap.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/plugins/fontawesome/css/all.min.css" rel="stylesheet"> <link href="https://cdn.waset.org/static/css/site.css?v=150220211555" rel="stylesheet"> </head> <body> <header> <div class="container"> <nav class="navbar navbar-expand-lg navbar-light"> <a class="navbar-brand" href="https://waset.org"> <img src="https://cdn.waset.org/static/images/wasetc.png" alt="Open Science Research Excellence" title="Open Science Research Excellence" /> </a> <button class="d-block d-lg-none navbar-toggler ml-auto" type="button" data-toggle="collapse" data-target="#navbarMenu" aria-controls="navbarMenu" aria-expanded="false" aria-label="Toggle navigation"> <span class="navbar-toggler-icon"></span> </button> <div class="w-100"> <div class="d-none d-lg-flex flex-row-reverse"> <form method="get" action="https://waset.org/search" class="form-inline my-2 my-lg-0"> <input class="form-control mr-sm-2" type="search" placeholder="Search Conferences" value="Thibault Lachard" name="q" aria-label="Search"> <button class="btn btn-light my-2 my-sm-0" type="submit"><i class="fas fa-search"></i></button> </form> </div> <div class="collapse navbar-collapse mt-1" id="navbarMenu"> <ul class="navbar-nav ml-auto align-items-center" id="mainNavMenu"> <li class="nav-item"> <a class="nav-link" href="https://waset.org/conferences" title="Conferences in 2024/2025/2026">Conferences</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/disciplines" title="Disciplines">Disciplines</a> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/committees" rel="nofollow">Committees</a> </li> <li class="nav-item dropdown"> <a class="nav-link dropdown-toggle" href="#" id="navbarDropdownPublications" role="button" data-toggle="dropdown" aria-haspopup="true" aria-expanded="false"> Publications </a> <div class="dropdown-menu" aria-labelledby="navbarDropdownPublications"> <a class="dropdown-item" href="https://publications.waset.org/abstracts">Abstracts</a> <a class="dropdown-item" href="https://publications.waset.org">Periodicals</a> <a class="dropdown-item" href="https://publications.waset.org/archive">Archive</a> </div> </li> <li class="nav-item"> <a class="nav-link" href="https://waset.org/page/support" title="Support">Support</a> </li> </ul> </div> </div> </nav> </div> </header> <main> <div class="container mt-4"> <div class="row"> <div class="col-md-9 mx-auto"> <form method="get" action="https://publications.waset.org/abstracts/search"> <div id="custom-search-input"> <div class="input-group"> <i class="fas fa-search"></i> <input type="text" class="search-query" name="q" placeholder="Author, Title, Abstract, Keywords" value="Thibault Lachard"> <input type="submit" class="btn_search" value="Search"> </div> </div> </form> </div> </div> <div class="row mt-3"> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Commenced</strong> in January 2007</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Frequency:</strong> Monthly</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Edition:</strong> International</div> </div> </div> <div class="col-sm-3"> <div class="card"> <div class="card-body"><strong>Paper Count:</strong> 7</div> </div> </div> </div> <h1 class="mt-3 mb-3 text-center" style="font-size:1.6rem;">Search results for: Thibault Lachard</h1> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">7</span> Electrical Cardiac Remodeling in Triathletes: A Comparative Study in Elite Male and Female Athletes</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lingxia%20Li">Lingxia Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Fr%C3%A9d%C3%A9ric%20Schnell"> Frédéric Schnell</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Lachard"> Thibault Lachard</a>, <a href="https://publications.waset.org/abstracts/search?q=Anne-Charlotte%20Dupont"> Anne-Charlotte Dupont</a>, <a href="https://publications.waset.org/abstracts/search?q=Shuzhe%20Ding"> Shuzhe Ding</a>, <a href="https://publications.waset.org/abstracts/search?q=Sol%C3%A8ne%20Le%20Douairon%20Lahaye"> Solène Le Douairon Lahaye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Prolonged intensive endurance exercise is associated with cardiovascular adaptations in athletes. However, the sex differences in electrocardiographic (ECG) performance in triathletes are poorly understood. Methods: ECG results of male and female triathletes registered on the French ministerial lists of high-level athletes between 2015 and 2021 were involved. The ECG was evaluated according to commonly accepted criteria. Results: Eighty-six triathletes (male 50, female 36) were involved; the average age was 19.9 ± 4.8 years. The training volume was 21±6 hours/week in males and 19 ± 6 hours/week in females (p>0.05). Despite the relatively larger P wave (96.0 ± 12.0 vs. 89.9 ± 11.5 ms, p=0.02) and longer QRS complex (96.6 ± 11.1 vs. 90.3 ± 8.6 ms, p=0.005) in males than in females, all indicators were within normal ranges. The most common electrical manifestations were early repolarization (46.5%) and incomplete right bundle branch block (39.5%). No difference between sexes was found in electrical manifestations (p > 0.05). Conclusion: All ECG patterns were within normal limits under similar training volumes, but male triathletes were more susceptible to cardiovascular changes than females. The most common ECG manifestations in triathletes were early repolarization and incomplete right bundle branch block, with no disparity between males and females. Large samples involving both sexes are required. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiovascular%20remodeling" title="cardiovascular remodeling">cardiovascular remodeling</a>, <a href="https://publications.waset.org/abstracts/search?q=electrocardiography" title=" electrocardiography"> electrocardiography</a>, <a href="https://publications.waset.org/abstracts/search?q=triathlon" title=" triathlon"> triathlon</a>, <a href="https://publications.waset.org/abstracts/search?q=elite%20athletes" title=" elite athletes"> elite athletes</a> </p> <a href="https://publications.waset.org/abstracts/194894/electrical-cardiac-remodeling-in-triathletes-a-comparative-study-in-elite-male-and-female-athletes" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194894.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">6</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">6</span> Electrical Cardiac Remodeling in Elite Athletes: A Comparative Study between Triathletes and Cyclists</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Lingxia%20Li">Lingxia Li</a>, <a href="https://publications.waset.org/abstracts/search?q=Fr%C3%A9d%C3%A9ric%20Schnell"> Frédéric Schnell</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Lachard"> Thibault Lachard</a>, <a href="https://publications.waset.org/abstracts/search?q=Anne-Charlotte%20Dupont"> Anne-Charlotte Dupont</a>, <a href="https://publications.waset.org/abstracts/search?q=Shuzhe%20Ding"> Shuzhe Ding</a>, <a href="https://publications.waset.org/abstracts/search?q=Sol%C3%A8ne%20Le%20Douairon%20Lahaye"> Solène Le Douairon Lahaye</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Background: Repetitive participation in triathlon training results in significant myocardial changes. However, whether the cardiac remodeling in triathletes is related to the specificities of the sport (consisting of three sports) raises questions. Methods: Elite triathletes and cyclists registered on the French ministerial lists of high-level athletes were involved. The basic information and routine electrocardiogram records were obtained. Electrocardiograms were evaluated according to clinical criteria. Results: Of the 105 athletes included in the study, 42 were from the short-distance triathlon (40%), and 63 were from the road cycling (60%). The average age was 22.1±4.2 years. The P wave amplitude was significantly lower in triathletes than in cyclists (p=0.005), and no significant statistical difference was found in heart rate, RR interval, PR or PQ interval, QRS complex, QRS axe, QT interval, and QTc (p>0.05). All the measured parameters were within normal ranges. The most common electrical manifestations were early repolarization (60.95%) and incomplete right bundle branch block (43.81%); there was no statistical difference between the groups (p>0.05). Conclusions: Prolonged intensive endurance exercise training induces physiological cardiac remodeling in both triathletes and cyclists. The most common electrocardiogram manifestations were early repolarization and incomplete right bundle branch block. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=cardiac%20screening" title="cardiac screening">cardiac screening</a>, <a href="https://publications.waset.org/abstracts/search?q=electrocardiogram" title=" electrocardiogram"> electrocardiogram</a>, <a href="https://publications.waset.org/abstracts/search?q=triathlon" title=" triathlon"> triathlon</a>, <a href="https://publications.waset.org/abstracts/search?q=cycling" title=" cycling"> cycling</a>, <a href="https://publications.waset.org/abstracts/search?q=elite%20athletes" title=" elite athletes"> elite athletes</a> </p> <a href="https://publications.waset.org/abstracts/194909/electrical-cardiac-remodeling-in-elite-athletes-a-comparative-study-between-triathletes-and-cyclists" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/194909.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">4</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">5</span> Molecular Interactions Driving RNA Binding to hnRNPA1 Implicated in Neurodegeneration</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Sakina%20Fatima">Sakina Fatima</a>, <a href="https://publications.waset.org/abstracts/search?q=Joseph-Patrick%20W.%20E.%20Clarke"> Joseph-Patrick W. E. Clarke</a>, <a href="https://publications.waset.org/abstracts/search?q=Patricia%20A.%20Thibault"> Patricia A. Thibault</a>, <a href="https://publications.waset.org/abstracts/search?q=Subha%20Kalyaanamoorthy"> Subha Kalyaanamoorthy</a>, <a href="https://publications.waset.org/abstracts/search?q=Michael%20Levin"> Michael Levin</a>, <a href="https://publications.waset.org/abstracts/search?q=Aravindhan%20Ganesan"> Aravindhan Ganesan</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Heteronuclear ribonucleoprotein (hnRNPA1 or A1) is associated with the pathology of different diseases, including neurological disorders and cancers. In particular, the aggregation and dysfunction of A1 have been identified as a critical driver for neurodegeneration (NDG) in Multiple Sclerosis (MS). Structurally, A1 includes a low-complexity domain (LCD) and two RNA-recognition motifs (RRMs), and their interdomain coordination may play a crucial role in A1 aggregation. Previous studies propose that RNA-inhibitors or nucleoside analogs that bind to RRMs can potentially prevent A1 self-association. Therefore, molecular-level understanding of the structures, dynamics, and nucleotide interactions with A1 RRMs can be useful for developing therapeutics for NDG in MS. In this work, a combination of computational modelling and biochemical experiments were employed to analyze a set of RNA-A1 RRM complexes. Initially, the atomistic models of RNA-RRM complexes were constructed by modifying known crystal structures (e.g., PDBs: 4YOE and 5MPG), and through molecular docking calculations. The complexes were optimized using molecular dynamics simulations (200-400 ns), and their binding free energies were computed. The binding affinities of the selected complexes were validated using a thermal shift assay. Further, the most important molecular interactions that contributed to the overall stability of the RNA-A1 RRM complexes were deduced. The results highlight that adenine and guanine are the most suitable nucleotides for high-affinity binding with A1. These insights will be useful in the rational design of nucleotide-analogs for targeting A1 RRMs. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=hnRNPA1" title="hnRNPA1">hnRNPA1</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20docking" title=" molecular docking"> molecular docking</a>, <a href="https://publications.waset.org/abstracts/search?q=molecular%20dynamics" title=" molecular dynamics"> molecular dynamics</a>, <a href="https://publications.waset.org/abstracts/search?q=RNA-binding%20proteins" title=" RNA-binding proteins"> RNA-binding proteins</a> </p> <a href="https://publications.waset.org/abstracts/155246/molecular-interactions-driving-rna-binding-to-hnrnpa1-implicated-in-neurodegeneration" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/155246.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">119</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">4</span> Lexical Based Method for Opinion Detection on Tripadvisor Collection</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Faiza%20Belbachir">Faiza Belbachir</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Schienhinski"> Thibault Schienhinski</a> </p> <p class="card-text"><strong>Abstract:</strong></p> The massive development of online social networks allows users to post and share their opinions on various topics. With this huge volume of opinion, it is interesting to extract and interpret these information for different domains, e.g., product and service benchmarking, politic, system of recommendation. This is why opinion detection is one of the most important research tasks. It consists on differentiating between opinion data and factual data. The difficulty of this task is to determine an approach which returns opinionated document. Generally, there are two approaches used for opinion detection i.e. Lexical based approaches and Machine Learning based approaches. In Lexical based approaches, a dictionary of sentimental words is used, words are associated with weights. The opinion score of document is derived by the occurrence of words from this dictionary. In Machine learning approaches, usually a classifier is trained using a set of annotated document containing sentiment, and features such as n-grams of words, part-of-speech tags, and logical forms. Majority of these works are based on documents text to determine opinion score but dont take into account if these texts are really correct. Thus, it is interesting to exploit other information to improve opinion detection. In our work, we will develop a new way to consider the opinion score. We introduce the notion of trust score. We determine opinionated documents but also if these opinions are really trustable information in relation with topics. For that we use lexical SentiWordNet to calculate opinion and trust scores, we compute different features about users like (numbers of their comments, numbers of their useful comments, Average useful review). After that, we combine opinion score and trust score to obtain a final score. We applied our method to detect trust opinions in TRIPADVISOR collection. Our experimental results report that the combination between opinion score and trust score improves opinion detection. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=Tripadvisor" title="Tripadvisor">Tripadvisor</a>, <a href="https://publications.waset.org/abstracts/search?q=opinion%20detection" title=" opinion detection"> opinion detection</a>, <a href="https://publications.waset.org/abstracts/search?q=SentiWordNet" title=" SentiWordNet"> SentiWordNet</a>, <a href="https://publications.waset.org/abstracts/search?q=trust%20score" title=" trust score"> trust score</a> </p> <a href="https://publications.waset.org/abstracts/91179/lexical-based-method-for-opinion-detection-on-tripadvisor-collection" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/91179.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">198</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">3</span> Development of a Model for Predicting Radiological Risks in Interventional Cardiology</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Stefaan%20Carpentier">Stefaan Carpentier</a>, <a href="https://publications.waset.org/abstracts/search?q=Aya%20Al%20Masri"> Aya Al Masri</a>, <a href="https://publications.waset.org/abstracts/search?q=Fabrice%20Leroy"> Fabrice Leroy</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Julien"> Thibault Julien</a>, <a href="https://publications.waset.org/abstracts/search?q=Safoin%20Aktaou"> Safoin Aktaou</a>, <a href="https://publications.waset.org/abstracts/search?q=Malorie%20Martin"> Malorie Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Fouad%20Maaloul"> Fouad Maaloul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: During an 'Interventional Radiology (IR)' procedure, the patient's skin-dose may become very high for a burn, necrosis, and ulceration to appear. In order to prevent these deterministic effects, a prediction of the peak skin-dose for the patient is important in order to improve the post-operative care to be given to the patient. The objective of this study is to estimate, before the intervention, the patient dose for ‘Chronic Total Occlusion (CTO)’ procedures by selecting relevant clinical indicators. Materials and methods: 103 procedures were performed in the ‘Interventional Cardiology (IC)’ department using a Siemens Artis Zee image intensifier that provides the Air Kerma of each IC exam. Peak Skin Dose (PSD) was measured for each procedure using radiochromic films. Patient parameters such as sex, age, weight, and height were recorded. The complexity index J-CTO score, specific to each intervention, was determined by the cardiologist. A correlation method applied to these indicators allowed to specify their influence on the dose. A predictive model of the dose was created using multiple linear regressions. Results: Out of 103 patients involved in the study, 5 were excluded for clinical reasons and 2 for placement of radiochromic films outside the exposure field. 96 2D-dose maps were finally used. The influencing factors having the highest correlation with the PSD are the patient's diameter and the J-CTO score. The predictive model is based on these parameters. The comparison between estimated and measured skin doses shows an average difference of 0.85 ± 0.55 Gy for doses of less than 6 Gy. The mean difference between air-Kerma and PSD is 1.66 Gy ± 1.16 Gy. Conclusion: Using our developed method, a first estimate of the dose to the skin of the patient is available before the start of the procedure, which helps the cardiologist in carrying out its intervention. This estimation is more accurate than that provided by the Air-Kerma. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=chronic%20total%20occlusion%20procedures" title="chronic total occlusion procedures">chronic total occlusion procedures</a>, <a href="https://publications.waset.org/abstracts/search?q=clinical%20experimentation" title=" clinical experimentation"> clinical experimentation</a>, <a href="https://publications.waset.org/abstracts/search?q=interventional%20radiology" title=" interventional radiology"> interventional radiology</a>, <a href="https://publications.waset.org/abstracts/search?q=patient%27s%20peak%20skin%20dose" title=" patient's peak skin dose"> patient's peak skin dose</a> </p> <a href="https://publications.waset.org/abstracts/119029/development-of-a-model-for-predicting-radiological-risks-in-interventional-cardiology" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/119029.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">136</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">2</span> Skin-Dose Mapping for Patients Undergoing Interventional Radiology Procedures: Clinical Experimentations versus a Mathematical Model</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aya%20Al%20Masri">Aya Al Masri</a>, <a href="https://publications.waset.org/abstracts/search?q=Stefaan%20Carpentier"> Stefaan Carpentier</a>, <a href="https://publications.waset.org/abstracts/search?q=Fabrice%20Leroy"> Fabrice Leroy</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Julien"> Thibault Julien</a>, <a href="https://publications.waset.org/abstracts/search?q=Safoin%20Aktaou"> Safoin Aktaou</a>, <a href="https://publications.waset.org/abstracts/search?q=Malorie%20Martin"> Malorie Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Fouad%20Maaloul"> Fouad Maaloul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: During an 'Interventional Radiology (IR)' procedure, the patient's skin-dose may become very high for a burn, necrosis and ulceration to appear. In order to prevent these deterministic effects, an accurate calculation of the patient skin-dose mapping is essential. For most machines, the 'Dose Area Product (DAP)' and fluoroscopy time are the only information available for the operator. These two parameters are a very poor indicator of the peak skin dose. We developed a mathematical model that reconstructs the magnitude (delivered dose), shape, and localization of each irradiation field on the patient skin. In case of critical dose exceeding, the system generates warning alerts. We present the results of its comparison with clinical studies. Materials and methods: Two series of comparison of the skin-dose mapping of our mathematical model with clinical studies were performed: 1. At a first time, clinical tests were performed on patient phantoms. Gafchromic films were placed on the table of the IR machine under of PMMA plates (thickness = 20 cm) that simulate the patient. After irradiation, the film darkening is proportional to the radiation dose received by the patient's back and reflects the shape of the X-ray field. After film scanning and analysis, the exact dose value can be obtained at each point of the mapping. Four experimentation were performed, constituting a total of 34 acquisition incidences including all possible exposure configurations. 2. At a second time, clinical trials were launched on real patients during real 'Chronic Total Occlusion (CTO)' procedures for a total of 80 cases. Gafchromic films were placed at the back of patients. We performed comparisons on the dose values, as well as the distribution, and the shape of irradiation fields between the skin dose mapping of our mathematical model and Gafchromic films. Results: The comparison between the dose values shows a difference less than 15%. Moreover, our model shows a very good geometric accuracy: all fields have the same shape, size and location (uncertainty < 5%). Conclusion: This study shows that our model is a reliable tool to warn physicians when a high radiation dose is reached. Thus, deterministic effects can be avoided. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=clinical%20experimentation" title="clinical experimentation">clinical experimentation</a>, <a href="https://publications.waset.org/abstracts/search?q=interventional%20radiology" title=" interventional radiology"> interventional radiology</a>, <a href="https://publications.waset.org/abstracts/search?q=mathematical%20model" title=" mathematical model"> mathematical model</a>, <a href="https://publications.waset.org/abstracts/search?q=patient%27s%20skin-dose%20mapping." title=" patient's skin-dose mapping."> patient's skin-dose mapping.</a> </p> <a href="https://publications.waset.org/abstracts/118816/skin-dose-mapping-for-patients-undergoing-interventional-radiology-procedures-clinical-experimentations-versus-a-mathematical-model" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/118816.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">140</span> </span> </div> </div> <div class="card paper-listing mb-3 mt-3"> <h5 class="card-header" style="font-size:.9rem"><span class="badge badge-info">1</span> Calculation of Organ Dose for Adult and Pediatric Patients Undergoing Computed Tomography Examinations: A Software Comparison</h5> <div class="card-body"> <p class="card-text"><strong>Authors:</strong> <a href="https://publications.waset.org/abstracts/search?q=Aya%20Al%20Masri">Aya Al Masri</a>, <a href="https://publications.waset.org/abstracts/search?q=Naima%20Oubenali"> Naima Oubenali</a>, <a href="https://publications.waset.org/abstracts/search?q=Safoin%20Aktaou"> Safoin Aktaou</a>, <a href="https://publications.waset.org/abstracts/search?q=Thibault%20Julien"> Thibault Julien</a>, <a href="https://publications.waset.org/abstracts/search?q=Malorie%20Martin"> Malorie Martin</a>, <a href="https://publications.waset.org/abstracts/search?q=Fouad%20Maaloul"> Fouad Maaloul</a> </p> <p class="card-text"><strong>Abstract:</strong></p> Introduction: The increased number of performed 'Computed Tomography (CT)' examinations raise public concerns regarding associated stochastic risk to patients. In its Publication 102, the ‘International Commission on Radiological Protection (ICRP)’ emphasized the importance of managing patient dose, particularly from repeated or multiple examinations. We developed a Dose Archiving and Communication System that gives multiple dose indexes (organ dose, effective dose, and skin-dose mapping) for patients undergoing radiological imaging exams. The aim of this study is to compare the organ dose values given by our software for patients undergoing CT exams with those of another software named "VirtualDose". Materials and methods: Our software uses Monte Carlo simulations to calculate organ doses for patients undergoing computed tomography examinations. The general calculation principle consists to simulate: (1) the scanner machine with all its technical specifications and associated irradiation cases (kVp, field collimation, mAs, pitch ...) (2) detailed geometric and compositional information of dozens of well identified organs of computational hybrid phantoms that contain the necessary anatomical data. The mass as well as the elemental composition of the tissues and organs that constitute our phantoms correspond to the recommendations of the international organizations (namely the ICRP and the ICRU). Their body dimensions correspond to reference data developed in the United States. Simulated data was verified by clinical measurement. To perform the comparison, 270 adult patients and 150 pediatric patients were used, whose data corresponds to exams carried out in France hospital centers. The comparison dataset of adult patients includes adult males and females for three different scanner machines and three different acquisition protocols (Head, Chest, and Chest-Abdomen-Pelvis). The comparison sample of pediatric patients includes the exams of thirty patients for each of the following age groups: new born, 1-2 years, 3-7 years, 8-12 years, and 13-16 years. The comparison for pediatric patients were performed on the “Head” protocol. The percentage of the dose difference were calculated for organs receiving a significant dose according to the acquisition protocol (80% of the maximal dose). Results: Adult patients: for organs that are completely covered by the scan range, the maximum percentage of dose difference between the two software is 27 %. However, there are three organs situated at the edges of the scan range that show a slightly higher dose difference. Pediatric patients: the percentage of dose difference between the two software does not exceed 30%. These dose differences may be due to the use of two different generations of hybrid phantoms by the two software. Conclusion: This study shows that our software provides a reliable dosimetric information for patients undergoing Computed Tomography exams. <p class="card-text"><strong>Keywords:</strong> <a href="https://publications.waset.org/abstracts/search?q=adult%20and%20pediatric%20patients" title="adult and pediatric patients">adult and pediatric patients</a>, <a href="https://publications.waset.org/abstracts/search?q=computed%20tomography" title=" computed tomography"> computed tomography</a>, <a href="https://publications.waset.org/abstracts/search?q=organ%20dose%20calculation" title=" organ dose calculation"> organ dose calculation</a>, <a href="https://publications.waset.org/abstracts/search?q=software%20comparison" title=" software comparison"> software comparison</a> </p> <a href="https://publications.waset.org/abstracts/118810/calculation-of-organ-dose-for-adult-and-pediatric-patients-undergoing-computed-tomography-examinations-a-software-comparison" class="btn btn-primary btn-sm">Procedia</a> <a href="https://publications.waset.org/abstracts/118810.pdf" target="_blank" class="btn btn-primary btn-sm">PDF</a> <span class="bg-info text-light px-1 py-1 float-right rounded"> Downloads <span class="badge badge-light">162</span> </span> </div> </div> </div> </main> <footer> <div id="infolinks" class="pt-3 pb-2"> <div class="container"> <div style="background-color:#f5f5f5;" class="p-3"> <div class="row"> <div class="col-md-2"> <ul class="list-unstyled"> About <li><a href="https://waset.org/page/support">About Us</a></li> <li><a href="https://waset.org/page/support#legal-information">Legal</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/WASET-16th-foundational-anniversary.pdf">WASET celebrates its 16th foundational anniversary</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Account <li><a href="https://waset.org/profile">My Account</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Explore <li><a href="https://waset.org/disciplines">Disciplines</a></li> <li><a href="https://waset.org/conferences">Conferences</a></li> <li><a href="https://waset.org/conference-programs">Conference Program</a></li> <li><a href="https://waset.org/committees">Committees</a></li> <li><a href="https://publications.waset.org">Publications</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Research <li><a href="https://publications.waset.org/abstracts">Abstracts</a></li> <li><a href="https://publications.waset.org">Periodicals</a></li> <li><a href="https://publications.waset.org/archive">Archive</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Open Science <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Philosophy.pdf">Open Science Philosophy</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Science-Award.pdf">Open Science Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Open-Society-Open-Science-and-Open-Innovation.pdf">Open Innovation</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Postdoctoral-Fellowship-Award.pdf">Postdoctoral Fellowship Award</a></li> <li><a target="_blank" rel="nofollow" href="https://publications.waset.org/static/files/Scholarly-Research-Review.pdf">Scholarly Research Review</a></li> </ul> </div> <div class="col-md-2"> <ul class="list-unstyled"> Support <li><a href="https://waset.org/page/support">Support</a></li> <li><a href="https://waset.org/profile/messages/create">Contact Us</a></li> <li><a href="https://waset.org/profile/messages/create">Report Abuse</a></li> </ul> </div> </div> </div> </div> </div> <div class="container text-center"> <hr style="margin-top:0;margin-bottom:.3rem;"> <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" class="text-muted small">Creative Commons Attribution 4.0 International License</a> <div id="copy" class="mt-2">© 2024 World Academy of Science, Engineering and Technology</div> </div> </footer> <a href="javascript:" id="return-to-top"><i class="fas fa-arrow-up"></i></a> <div class="modal" id="modal-template"> <div class="modal-dialog"> <div class="modal-content"> <div class="row m-0 mt-1"> <div class="col-md-12"> <button type="button" class="close" data-dismiss="modal" aria-label="Close"><span aria-hidden="true">×</span></button> </div> </div> <div class="modal-body"></div> </div> </div> </div> <script src="https://cdn.waset.org/static/plugins/jquery-3.3.1.min.js"></script> <script src="https://cdn.waset.org/static/plugins/bootstrap-4.2.1/js/bootstrap.bundle.min.js"></script> <script src="https://cdn.waset.org/static/js/site.js?v=150220211556"></script> <script> jQuery(document).ready(function() { /*jQuery.get("https://publications.waset.org/xhr/user-menu", function (response) { jQuery('#mainNavMenu').append(response); });*/ jQuery.get({ url: "https://publications.waset.org/xhr/user-menu", cache: false }).then(function(response){ jQuery('#mainNavMenu').append(response); }); }); </script> </body> </html>